AutismKB 2.0

Annotation Detail for FBLN7


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:FBLN7 ( DKFZp547D0610,FLJ37440,TM14 )
Gene Full Name: fibulin 7
Band: 2q13
Quick LinksEntrez ID:129804; OMIM: 611551; Uniprot ID:FBLN7_HUMAN; ENSEMBL ID: ENSG00000144152; HGNC ID: 26740
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of FBLN7 mRNAaffects expression 17562736
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of FBLN7 proteinaffects expression 20106945
C015001 arsenite arsenite results in increased expression of FBLN7 mRNAincreases expression 18929588
C015001 arsenite TRP53 protein affects the reaction [arsenite results in increased expression of FBLN7 mRNA]affects reaction|increases expression 18929588
D016572 Cyclosporine Cyclosporine results in decreased expression of FBLN7 mRNAdecreases expression 20106945
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.5710982225
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 3.033084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 3.0312907637 12619106 21507988
MESH:D002386 Cataract Acetaminophen 2.7910977129
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.7912371664
MESH:D002779 Cholestasis Cyclosporine 3.2119486331
MESH:D003110 Colonic Neoplasms arsenite 2.6315037631
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6716781746 19164858 19739265 19923254 19416960 14550746 14725611 11834606 11461765 16227642 17906064 12392966 18071297 11743745 11421492 10774834 16177239 11529661 19085960 17562736 15968718 15619225 11287661 10663392 10915739 18713872 17522070 19420014 16081117 14986274 12705907 11739529 12958197 12594235 16109766 12540782 2444490 16485898 12153990 16393943 19370779
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.8219426721
MESH:D005234 Fatty Liver arsenite 9.3818296743
MESH:D005234 Fatty Liver Cyclosporine 9.3819224547
MESH:D005355 Fibrosis arsenite 10.8318296743
MESH:D005355 Fibrosis Cyclosporine 10.8312639820 12168785
MESH:D005756 Gastritis Acetaminophen 4.4016983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.858708960
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 5.0515720958
MESH:D006930 Hyperalgesia Acetaminophen 3.0216870215
MESH:D006973 Hypertension Cyclosporine 2.2110903974
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.1615604871
MESH:D007674 Kidney Diseases Acetaminophen 6.4815629191 12587719
MESH:D007674 Kidney Diseases Cyclosporine 6.4818776723 8314463 10903974
MESH:D007680 Kidney Neoplasms Cyclosporine 3.0812371664
MESH:D008103 Liver Cirrhosis arsenite 3.6118296743
MESH:D008107 Liver Diseases Acetaminophen 1.7016611625 19784758 16610002 12587719 12969438 11587558 19460945 19014921
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6316871587 17185352
MESH:D008113 Liver Neoplasms Aflatoxin B1 2.4615890375 2125692 18177683 9163691
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 2.968603461
MESH:D008175 Lung Neoplasms Aflatoxin B1 2.8014755239
MESH:D008175 Lung Neoplasms arsenite 2.8016809336
MESH:D008546 Melanoma, Experimental Acetaminophen 4.1319513568
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.5116801185
MESH:D009389 Neovascularization, Pathologic arsenite 5.0415738583
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.1617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.6519348381 18481113
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2118514411
MESH:D010146 Pain Acetaminophen 2.7316870215
MESH:D011230 Precancerous Conditions Cyclosporine 3.5912371664
MESH:D011565 Psoriasis Cyclosporine 2.3316882103
MESH:D014581 Urticaria Acetaminophen 3.4410982225
MESH:D014605 Uveitis Cyclosporine 4.711336536
MESH:D014985 Xerophthalmia Cyclosporine 5.1617120751
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018