AutismKB 2.0

Annotation Detail for COL13A1


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Basic Information Top
Gene Symbol:COL13A1 ( COLXIIIA1,FLJ42485 )
Gene Full Name: collagen, type XIII, alpha 1
Band: 10q22.1
Quick LinksEntrez ID:1305; OMIM: 120350; Uniprot ID:CODA1_HUMAN; ENSEMBL ID: ENSG00000197467; HGNC ID: 2190
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
P00034Integrin signalling pathway
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of COL13A1 mRNAincreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of COL13A1 mRNAaffects expression 17562736
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of COL13A1 mRNAdecreases expression 20064835
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of COL13A1 mRNAincreases expression 15336504
D002117 Calcitriol Calcitriol results in increased expression of COL13A1 mRNAincreases expression 16002434
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of COL13A1 mRNAaffects cotreatment|increases expression 17942748
C051890 irinotecan irinotecan analog results in increased expression of COL13A1 mRNAincreases expression 18927307
D007529 Isoflavones Isoflavones affects the expression of COL13A1 mRNAaffects expression 16365062
C030110 oxaliplatin oxaliplatin results in decreased expression of COL13A1 mRNAdecreases expression 16510598
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of COL13A1 mRNAincreases expression 20106945
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of COL13A1 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of COL13A1 mRNAincreases expression 16120747
D014212 Tretinoin Tretinoin results in increased expression of COL13A1 mRNAincreases expression 16604517
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.0411752688 15322242 14514962
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.1617505938
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.2820127859 20464547
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.2814692618
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 6.853712494
MESH:D000236 Adenoma Benzo(a)pyrene 6.856695378
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.5716835633
MESH:D000505 Alopecia Isoflavones 9.9517569567
MESH:D000505 Alopecia Tretinoin 9.9515955085
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.0811748828
MESH:D000799 Angioedema Acetaminophen 4.0610982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.2519183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.6411256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.4815885639
MESH:D001169 Arthritis, Experimental Tretinoin 7.4816412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2916292516
MESH:D001249 Asthma Tretinoin 2.3816456186
MESH:D001321 Autistic Disorder Acetaminophen 1.4118445737
MESH:D001471 Barrett Esophagus Tretinoin 4.5616935849
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.241440618 11289319
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 9.4112125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 9.4116206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.0115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.8515746008
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.9620146248 17474063
MESH:D001943 Breast Neoplasms Calcitriol 1.9611237771
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9620435547
MESH:D001943 Breast Neoplasms Tretinoin 1.9616166294 16443354 16873071
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.7816813970
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.9116835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.3816168501
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 4.633581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.633084413
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 4.631917145
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.737296757
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 7.7620419170
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 7.7611237771
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 7.7616096774 16051514
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.4416120746 18670907 18850075
MESH:D002318 Cardiovascular Diseases Isoflavones 4.2417689850
MESH:D002386 Cataract Acetaminophen 7.4810977129
MESH:D002386 Cataract Tretinoin 7.4817460283
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 2.857505956
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.7816129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.2916835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 8.2119486331 9022650
MESH:D002779 Cholestasis Ethinyl Estradiol 8.2116105132 11677210 16919318 17110522 17681005 17333356 15861022
MESH:D002822 Choriocarcinoma Tretinoin 5.3816461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.9412621046 15340226 15668235 16354765 8697196
MESH:D002972 Cleft Palate Tretinoin 5.949407595
MESH:D003092 Colitis Tretinoin 3.8817035595
MESH:D003110 Colonic Neoplasms irinotecan 4.3917287894 17725105
MESH:D003110 Colonic Neoplasms oxaliplatin 4.3916510598 16004971 16024531
MESH:D015179 Colorectal Neoplasms irinotecan 3.8416391804 18259882 18509181 17159606 15273666 17454858 16303861
MESH:D015179 Colorectal Neoplasms Isoflavones 3.8417116718
MESH:D015179 Colorectal Neoplasms oxaliplatin 3.8417695437 17255274 18509181 18448328 17401013 17594712
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.1817141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4815322242 10048152 20055451
MESH:D019465 Craniofacial Abnormalities Tretinoin 2.489142499 17551590 9211117 16925845 9224671 10589399 14991402 8800419 9664655 9125849
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.9718759878 11298694 8156756 8970840 12868966 11906362 2524372 14531868
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.642952479 3621924
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6917107852
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 6.3316192314 18692083 7440962 18289764 6482804 9022650 11289319 8291058 18648102 9653073 6679447 1440618 9328219
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.3310663392 12705907 19923254 19085960 11529661 15968718 12153990 10915739 16393943 16177239 14986274 11421492 17562736 11287661 19420014 17522070 12594235 16081117 10774834 17906064 11743745 18071297 12958197 16109766 14550746 16781746 16485898 19739265 19164858 11461765 15619225 11739529 12540782 18713872 12392966 19416960 16227642 14725611 2444490 19370779 11834606
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 6.3320420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.3219426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.8611462148
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.5111000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 12.6818230668 15322242 16714409
MESH:D004489 Edema, Cardiac Tretinoin 12.6818230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 9.6415138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 9.6412538720
MESH:D016889 Endometrial Neoplasms Tretinoin 3.1916569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.1510568697 9294722
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 4.473581430
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.4716530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 9.1811564622
MESH:D005124 Eye Abnormalities Tretinoin 9.189664655 16938888
MESH:D005234 Fatty Liver Ethinyl Estradiol 2.9515345470
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.6311858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.246705139
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 9.2120067830
MESH:D005355 Fibrosis Tretinoin 9.2117994277
MESH:D005756 Gastritis Acetaminophen 3.8916983495
MESH:D005909 Glioblastoma Tretinoin 3.0917312396
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.197505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.8110696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.2716096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.3816084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 11.4920471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 11.4911294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 11.4914991402 9664655
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.4811000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.676705139
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.0715340226 16120746 12621046
MESH:D019584 Hot Flashes Isoflavones 5.2014716179 17290160
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.2615340226 16354765 8697196 18606429 16959395
MESH:D006930 Hyperalgesia Acetaminophen 13.8216870215
MESH:D006930 Hyperalgesia oxaliplatin 13.8217418472
MESH:D006930 Hyperalgesia Tretinoin 13.8216870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.7416778211
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.1115034207
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9518850075 18670907
MESH:D007021 Hypospadias Ethinyl Estradiol 3.9816945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.6112013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.5717937319
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 1.9212200463 12878042
MESH:D007410 Intestinal Diseases Tretinoin 3.9417994277
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.248074119 9022650
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 10.4016580747
MESH:D007569 Jaw Abnormalities Tretinoin 10.4015992940 17551590
MESH:D007674 Kidney Diseases Acetaminophen 2.2712587719 15629191
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 3.086582329
MESH:D007938 Leukemia Tretinoin 2.8317143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.8416932348 19285840 16482212
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.1019850784 17596541 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.2417712046 19029980 17649720 16331271 19035177 17217047 19642359 16140955 16823087 17506722 17294898 17301526 17339181 16766008 9834237 15748426 16788101 17368321 17107899 12679006 16891316 17361223 19075265 16935935 19225113
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.419224671
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.2815034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 2.3412878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 2.3418397230 16248980
MESH:D008107 Liver Diseases Acetaminophen 1.6616610002 12969438 11587558 16611625 12587719 19784758 19014921 19460945
MESH:D017114 Liver Failure, Acute Acetaminophen 3.3717185352 16871587
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 4.4920195826 21137059
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 4.4916984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 6.011399818 598648 6587162 3712494
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 6.0112151625
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 2.2220869020 18816296 17053015 6695378 20064080 20135361 18520028 20464547 18569708
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 2.2211884234 19555203
MESH:D008527 Medulloblastoma Tretinoin 2.8317453147
MESH:D008545 Melanoma Tretinoin 1.9616752155
MESH:D008546 Melanoma, Experimental Acetaminophen 3.7419513568
MESH:D008591 Meningomyelocele Tretinoin 4.6016940565
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.3016381670
MESH:D052016 Mucositis irinotecan 5.2017159606
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.1517596541
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.1312213967
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 6.093581430
MESH:D009362 Neoplasm Metastasis irinotecan 6.0918259882
MESH:D009369 Neoplasms Benzo(a)pyrene 5.2011141357
MESH:D009369 Neoplasms Tretinoin 5.2016946489 16594593
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 10.0614600291
MESH:D009421 Nervous System Malformations Tretinoin 10.069125849
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 7.526679447
MESH:D009436 Neural Tube Defects Tretinoin 7.529142499
MESH:D009447 Neuroblastoma irinotecan 3.548761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.9918514411
MESH:D017599 Neuroectodermal Tumors irinotecan 4.928761367
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.556482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.243988306
MESH:D010024 Osteoporosis Isoflavones 4.1816562857
MESH:D010051 Ovarian Neoplasms Tretinoin 2.3816936753
MESH:D010146 Pain Acetaminophen 6.9816870215
MESH:D010146 Pain Tretinoin 6.9816870215
MESH:D010190 Pancreatic Neoplasms Tretinoin 2.5015976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.8411578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.667296757
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.4712520081
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.696228378
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.7218163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.3811896295 11118676 11222880 11399792
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.9715572423
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.7017292933
MESH:D011471 Prostatic Neoplasms Calcitriol 2.7012479363 15754350 16644109 18247401 16289102
MESH:D011471 Prostatic Neoplasms Isoflavones 2.7017374662 16365062 17571952 17219775
MESH:D011507 Proteinuria Tretinoin 3.7516636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.5115861022 16919318
MESH:D011625 Pterygium Tretinoin 4.9916723453
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.0018990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.483692021
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.2516116481 16283617
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 14.0519755658 10029692
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 14.058532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 14.0516192470
MESH:D012878 Skin Neoplasms Tretinoin 14.0516467112
MESH:D013088 Spermatocele Ethinyl Estradiol 4.1616709447
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 3.472093021 20155912
MESH:D013274 Stomach Neoplasms irinotecan 3.4715723263
MESH:D013274 Stomach Neoplasms Tretinoin 3.4717261132
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.7711994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.2815669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.1212697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 7.493712494 7505956 1399818 6582329 6587162
MESH:D013964 Thyroid Neoplasms Tretinoin 7.4917045167 16026305
MESH:D014062 Tongue Neoplasms Tretinoin 3.9216051514
MESH:D014376 Tuberculosis Tretinoin 3.3116040207
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 5.138074119
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 5.1317053015
MESH:D014581 Urticaria Acetaminophen 3.1210982225
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.8116129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.4614692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.8316752155
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.8112125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.6815869587 14671159
MESH:D014820 Vitiligo Tretinoin 4.2216761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.4715886252
MESH:D009396 Wilms Tumor Tretinoin 4.0916287080
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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