AutismKB 2.0

Annotation Detail for UBR3


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Basic Information Top
Gene Symbol:UBR3 ( DKFZp434P117,DKFZp686N10185,FLJ37422,KIAA2024,MGC126489,ZNF650 )
Gene Full Name: ubiquitin protein ligase E3 component n-recognin 3 (putative)
Band: 2q31.1
Quick LinksEntrez ID:130507; OMIM: NA; Uniprot ID:UBR3_HUMAN; ENSEMBL ID: ENSG00000144357; HGNC ID: 30467
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of UBR3 mRNAaffects expression 17562736
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 5.2610982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.8610977129
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6915619225 19420014 16177239 14986274 19085960 19739265 19164858 12153990 12594235 11743745 16109766 18713872 12958197 10663392 19370779 15968718 12392966 11739529 16081117 11287661 16393943 17522070 16485898 11421492 10774834 11834606 17562736 16227642 19923254 12540782 2444490 10915739 14725611 18071297 11461765 16781746 11529661 14550746 19416960 12705907 17906064
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.5119426721
MESH:D005756 Gastritis Acetaminophen 5.0916983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1516870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4712587719 15629191
MESH:D008107 Liver Diseases Acetaminophen 1.7212969438 16610002 16611625 12587719 19014921 11587558 19784758 19460945
MESH:D017114 Liver Failure, Acute Acetaminophen 3.8116871587 17185352
MESH:D008546 Melanoma, Experimental Acetaminophen 4.4719513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3618514411
MESH:D010146 Pain Acetaminophen 2.8716870215
MESH:D014581 Urticaria Acetaminophen 3.6710982225
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018