AutismKB 2.0

Annotation Detail for FBXO36


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Basic Information Top
Gene Symbol:FBXO36 ( FLJ37592,FLJ41090,Fbx36 )
Gene Full Name: F-box protein 36
Band: 2q36.3
Quick LinksEntrez ID:130888; OMIM: 609105; Uniprot ID:FBX36_HUMAN; ENSEMBL ID: ENSG00000153832; HGNC ID: 27020
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of FBXO36 mRNAincreases expression 19933214
D000082 Acetaminophen Acetaminophen affects the expression of FBXO36 mRNAaffects expression 17562736
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.9110982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.8310977129
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6811287661 15619225 11529661 12392966 19739265 17562736 10915739 12594235 12540782 19164858 14550746 16393943 10774834 19420014 14986274 18713872 11834606 16485898 17906064 11739529 16177239 11743745 12705907 19370779 14725611 19923254 19416960 2444490 16081117 12153990 11421492 10663392 11461765 15968718 17522070 16109766 16227642 19085960 16781746 12958197 18071297
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.1719426721
MESH:D005756 Gastritis Acetaminophen 4.7416983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1116870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4412587719 15629191
MESH:D008107 Liver Diseases Acetaminophen 1.7116610002 19460945 12587719 19784758 11587558 19014921 16611625 12969438
MESH:D017114 Liver Failure, Acute Acetaminophen 3.7416871587 17185352
MESH:D008546 Melanoma, Experimental Acetaminophen 4.3319513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3118514411
MESH:D010146 Pain Acetaminophen 2.8216870215
MESH:D014581 Urticaria Acetaminophen 3.5810982225
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018