AutismKB 2.0

Annotation Detail for TPRA1


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Basic Information Top
Gene Symbol:TPRA1 ( FLJ32197,GPR175,TMEM227,TPRA40 )
Gene Full Name: transmembrane protein, adipocyte asscociated 1
Band: 3q21.3
Quick LinksEntrez ID:131601; OMIM: 608336; Uniprot ID:TPRA1_HUMAN; ENSEMBL ID: ENSG00000163870; HGNC ID: 30413
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of TPRA1 mRNAaffects expression 16483693
D010126 Ozone Ozone results in decreased expression of TPRA1 mRNAdecreases expression 12763052
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.4418287403
MESH:D000544 Alzheimer Disease Ozone 2.5115513908
MESH:D001172 Arthritis, Rheumatoid Ozone 2.6415570426
MESH:D001249 Asthma Ozone 2.7517854713 16373670
MESH:D016535 Bronchial Hyperreactivity Ozone 4.0814754758 15516495 19059883 18315731 17626835 16777450 18417511
MESH:D002100 Cachexia Ozone 5.6316183385
MESH:D008171 Lung Diseases Ozone 3.688266340 19066396
MESH:D055370 Lung Injury Ozone 4.6120417186
MESH:D008175 Lung Neoplasms Ozone 2.107614698 8597069
MESH:D008679 Metaplasia Ozone 6.1810496685
MESH:D010538 Peritonitis Ozone 4.8916369182
MESH:D011014 Pneumonia Ozone 5.2818007984 18929643 18381685
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018