AutismKB 2.0

Annotation Detail for TMEM42


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Basic Information Top
Gene Symbol:TMEM42 ( MGC29956 )
Gene Full Name: transmembrane protein 42
Band: 3p21.31
Quick LinksEntrez ID:131616; OMIM: NA; Uniprot ID:TMM42_HUMAN; ENSEMBL ID: ENSG00000169964; HGNC ID: 28444
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
D016572 Cyclosporine Cyclosporine results in decreased expression of TMEM42 mRNAdecreases expression 20106945
D004041 Dietary Fats Dietary Fats results in increased expression of TMEM42 mRNAincreases expression 18042831
C041786 palm oil palm oil results in increased expression of TMEM42 mRNAincreases expression 18042831
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D001161 Arteriosclerosis Dietary Fats 4.5415238619
MESH:D001943 Breast Neoplasms Dietary Fats 2.2420435547
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.8212371664
MESH:D002779 Cholestasis Cyclosporine 3.2419486331
MESH:D050171 Dyslipidemias Dietary Fats 3.7618367378
MESH:D005234 Fatty Liver Cyclosporine 9.3819224547
MESH:D005234 Fatty Liver Dietary Fats 9.3817967931 18296743 19551842 19004024
MESH:D005355 Fibrosis Cyclosporine 10.9612639820 12168785
MESH:D005355 Fibrosis Dietary Fats 10.9618296743
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.968708960
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 5.1615720958
MESH:D006937 Hypercholesterolemia Dietary Fats 4.0821332399
MESH:D006949 Hyperlipidemias Dietary Fats 4.1421332399
MESH:D006973 Hypertension Cyclosporine 2.2310903974
MESH:D007249 Inflammation Dietary Fats 2.6220412841
MESH:D007333 Insulin Resistance Dietary Fats 3.3718457598 11836018
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.3115604871
MESH:D007674 Kidney Diseases Cyclosporine 2.568314463 10903974 18776723
MESH:D007680 Kidney Neoplasms Cyclosporine 3.1212371664
MESH:D008103 Liver Cirrhosis Dietary Fats 3.0918296743
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.6516801185
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.3117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.7018481113 19348381
MESH:D009765 Obesity Dietary Fats 2.3621332399 17217161 18674790 11836018 16723640 18457598 19632207 20132043 20518802
MESH:D011230 Precancerous Conditions Cyclosporine 3.6412371664
MESH:D011565 Psoriasis Cyclosporine 2.3416882103
MESH:D014605 Uveitis Cyclosporine 4.851336536
MESH:D015430 Weight Gain Dietary Fats 4.1516723640
MESH:D014985 Xerophthalmia Cyclosporine 5.3117120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018