AutismKB 2.0

Annotation Detail for IL17RE


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Basic Information Top
Gene Symbol:IL17RE ( FLJ23658,MGC71884 )
Gene Full Name: interleukin 17 receptor E
Band: 3p25.3
Quick LinksEntrez ID:132014; OMIM: NA; Uniprot ID:I17RE_HUMAN; ENSEMBL ID: ENSG00000163701; HGNC ID: 18439
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
C404910 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of IL17RE mRNA]affects expression|affects reaction 19414516
C404910 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [FSHB protein affects the expression of IL17RE mRNA]affects expression|affects reaction 19414516
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane affects the expression of IL17RE mRNAaffects expression 18648102
D000242 Cyclic AMP 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of IL17RE mRNA]affects expression|affects reaction 19414516
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of IL17RE mRNAdecreases expression 16239168
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.963712494
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.741440618 11289319
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 4.343786805 15673190 16050911 16227642 16192424 15700767 10355542 15721981 16124888 18705752 16011737 16097048
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 3.123581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 3.1218788625
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.837296757
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 3.027505956
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 3.449022650 19486331
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 3.352524372 18759878 14531868 12868966 11906362 8156756 11298694 8970840
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.953621924 2952479
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 4.1818692083 6679447 18289764 9653073 1440618 16192314 11289319 9328219 7440962 6482804 8291058 9022650 18648102
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 4.183786805 21278145 3732212 16227642 15027814 15968718 7179309 4309450 19336974 10915739 11566570 7440962 7120509 16177239 10092053 2869522 6884620 17522070 15998439 19085960 6623471 9327722
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.183581430
MESH:D005234 Fatty Liver Carbon Tetrachloride 3.5961145 15959796 16045604 12795759 17595544 12631006 16239168 19224547
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.746705139
MESH:D005355 Fibrosis Carbon Tetrachloride 4.0118705752
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.507505956
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 10.966705139
MESH:D006505 Hepatitis Carbon Tetrachloride 10.9619900420 19110552
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 5.1616899240
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.5015034207
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.6515338365
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.749022650 8074119
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 3.316582329
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 3.0016239168 16221502 11408273 11903743 16943688 21278145 17334410 17157831 17174718
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.4215034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 1.7518187930 17698563 18418968 17714472 17565644 15818738 18166357 12649538 16097048 15730626 16027843 18251166 17944888 18277467 17766677 18376398 12586293 18472094 15362042 12546737 13678700 14716496 12632512 14748882 15123356 18472332 16011737 17869086 16116963 12632514 12958196 17481882 20821823 12389079 15057751 17823541 10355542 15370692 18429990 15925388 15893842 17557913 12445421 18006644 17525996 14620537 16192424 17922224 14724832 18412020 18205269 16638106 12609069 18395914 18395095 14512876 17976157 16015684 18317297 18054572 18339082 12445418 15996030 16136751 17708605 15931870 11481614 12898905 18481824 12666154 15052691 17805973 12667390 15338365 15959796 16248980 12741479 15673190 15650968 18210741 17721639 17761835 18263696 17631135 18279442 17640975 17900296 18705752 18420326 14716833 15876570 18156304 16033810
MESH:D008107 Liver Diseases Carbon Tetrachloride 2.1515830285 15720792 16246199 17285989 16964402
MESH:D017093 Liver Failure Carbon Tetrachloride 4.7315123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 4.0814706259 16899240
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 2.3419294768
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 6.681399818 6587162 598648 3712494
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 6.6812014681 15583823
MESH:D020326 Migraine without Aura Cyclic AMP 5.6611304026
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.593581430
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 3.156679447
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.816482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.743988306
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 4.047296757
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 5.196228378
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.673692021
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 3.191399818 6582329 3712494 7505956 6587162
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 2.408074119
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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