AutismKB 2.0

Annotation Detail for H1FOO


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Basic Information Top
Gene Symbol:H1FOO ( MGC50807,osH1 )
Gene Full Name: H1 histone family, member O, oocyte-specific
Band: 3q22.1
Quick LinksEntrez ID:132243; OMIM: NA; Uniprot ID:H1FOO_HUMAN; ENSEMBL ID: ENSG00000178804; HGNC ID: 18463
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C014347 decitabine decitabine affects the methylation of H1FOO promoteraffects methylation 18184919
D014028 Tobacco Smoke Pollution Tobacco Smoke Pollution results in decreased expression of H1FOO mRNAdecreases expression 18087596
D014212 Tretinoin Tretinoin results in increased expression of H1FOO mRNAincreases expression 16604517
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Tobacco Smoke Pollution 6.4015814487
MESH:D000505 Alopecia Tretinoin 3.9815955085
MESH:D001169 Arthritis, Experimental Tretinoin 3.3216412693
MESH:D001172 Arthritis, Rheumatoid Tobacco Smoke Pollution 5.1719898480
MESH:D001172 Arthritis, Rheumatoid Tretinoin 5.1716292516
MESH:D001249 Asthma Tretinoin 2.4416456186
MESH:D001471 Barrett Esophagus Tretinoin 4.9916935849
MESH:D001778 Blood Coagulation Disorders Tretinoin 4.0916197459 16206674
MESH:D001943 Breast Neoplasms decitabine 2.2619208741 18320071
MESH:D001943 Breast Neoplasms Tretinoin 2.2616873071 16443354 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 5.3316813970
MESH:D018236 Carcinoma, Embryonal Tretinoin 6.0316168501
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 1.921917145
MESH:D002289 Carcinoma, Non-Small-Cell Lung Tobacco Smoke Pollution 3.5411212258
MESH:D002294 Carcinoma, Squamous Cell decitabine 8.2919215824
MESH:D002294 Carcinoma, Squamous Cell Tobacco Smoke Pollution 8.2911212258
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 8.2916096774 16051514
MESH:D002386 Cataract Tretinoin 3.3217460283
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 5.3316129372
MESH:D002822 Choriocarcinoma Tretinoin 6.0316461808
MESH:D002972 Cleft Palate Tretinoin 2.819407595
MESH:D003092 Colitis Tretinoin 4.3517035595
MESH:D003110 Colonic Neoplasms decitabine 2.3917616700
MESH:D015179 Colorectal Neoplasms decitabine 2.1118981723
MESH:D019465 Craniofacial Abnormalities Tretinoin 1.8316925845 9211117 17551590 9664655 10589399 9142499 8800419 9125849 14991402 9224671
MESH:D004489 Edema, Cardiac Tretinoin 5.3318230668
MESH:D004701 Endocrine Gland Neoplasms decitabine 5.9819294695
MESH:D016889 Endometrial Neoplasms Tretinoin 3.3716569247
MESH:D005124 Eye Abnormalities Tretinoin 3.909664655 16938888
MESH:D005355 Fibrosis Tretinoin 4.1617994277
MESH:D005909 Glioblastoma Tretinoin 3.2717312396
MESH:D006258 Head and Neck Neoplasms decitabine 8.7819215824
MESH:D006258 Head and Neck Neoplasms Tretinoin 8.7816096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 6.0316084493
MESH:D006330 Heart Defects, Congenital Tretinoin 3.0914991402 9664655
MESH:D006930 Hyperalgesia Tretinoin 3.5716870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 5.2216778211
MESH:D007248 Infertility, Male decitabine 3.4817581917
MESH:D007249 Inflammation Tobacco Smoke Pollution 3.5318590791
MESH:D007410 Intestinal Diseases Tretinoin 4.4217994277
MESH:D007569 Jaw Abnormalities Tretinoin 4.3917551590 15992940
MESH:D007938 Leukemia decitabine 7.0518980019 19235587
MESH:D007938 Leukemia Tretinoin 7.0517143497
MESH:D007951 Leukemia, Myeloid decitabine 11.2218454857 19117987 17236224
MESH:D007951 Leukemia, Myeloid Tretinoin 11.2219285840 16482212 16932348
MESH:D015470 Leukemia, Myeloid, Acute decitabine 4.1719010910 19387464 17679729 18206229 18460780 18704418
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 4.1717596541 16294345 19850784
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 6.3318055864
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.4217339181 17301526 16823087 17368321 17107899 16766008 16140955 12679006 19642359 15748426 9834237 16331271 19035177 16935935 17712046 17506722 16891316 17217047 17361223 19225113 17294898 19029980 19075265 16788101 17649720
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.629224671
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 1.8116248980 18397230
MESH:D008175 Lung Neoplasms Tobacco Smoke Pollution 2.7312111688 16288123 3440675 11091918
MESH:D008223 Lymphoma decitabine 3.7319470736
MESH:D008527 Medulloblastoma Tretinoin 2.9217453147
MESH:D008545 Melanoma decitabine 3.6016505122 17785578
MESH:D008545 Melanoma Tretinoin 3.6016752155
MESH:D008591 Meningomyelocele Tretinoin 5.0816940565
MESH:D009062 Mouth Neoplasms Tobacco Smoke Pollution 4.6915006635
MESH:D009101 Multiple Myeloma decitabine 3.6518172295
MESH:D009190 Myelodysplastic Syndromes decitabine 8.2219157545 18608210 19010910 16882708
MESH:D009190 Myelodysplastic Syndromes Tretinoin 8.2217596541
MESH:D009369 Neoplasms decitabine 5.8119470736 19116145 17925555
MESH:D009369 Neoplasms Tretinoin 5.8116946489 16594593
MESH:D009421 Nervous System Malformations Tretinoin 4.369125849
MESH:D009436 Neural Tube Defects Tretinoin 3.329142499
MESH:D010051 Ovarian Neoplasms decitabine 5.3219259094 19331143
MESH:D010051 Ovarian Neoplasms Tretinoin 5.3216936753
MESH:D010146 Pain Tretinoin 3.2816870215
MESH:D010190 Pancreatic Neoplasms decitabine 5.8019294695
MESH:D010190 Pancreatic Neoplasms Tretinoin 5.8015976015
MESH:D055728 Primary Myelofibrosis decitabine 5.3817616702
MESH:D011507 Proteinuria Tretinoin 4.1316636307
MESH:D011625 Pterygium Tretinoin 5.5416723453
MESH:D012135 Respiratory Sounds Tobacco Smoke Pollution 5.2718410779
MESH:D012208 Rhabdomyosarcoma decitabine 12.7719155313
MESH:D012208 Rhabdomyosarcoma Tretinoin 12.7716283617 16116481
MESH:D012878 Skin Neoplasms Tobacco Smoke Pollution 6.6918590791
MESH:D012878 Skin Neoplasms Tretinoin 6.6916467112
MESH:D013274 Stomach Neoplasms decitabine 2.6219037991
MESH:D013274 Stomach Neoplasms Tretinoin 2.6217261132
MESH:D013964 Thyroid Neoplasms decitabine 8.4517967635
MESH:D013964 Thyroid Neoplasms Tretinoin 8.4517045167 16026305
MESH:D014062 Tongue Neoplasms Tretinoin 4.2416051514
MESH:D014376 Tuberculosis Tretinoin 3.4716040207
MESH:D001749 Urinary Bladder Neoplasms decitabine 6.0217616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Tobacco Smoke Pollution 6.0212846360
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 4.1216129372
MESH:D014604 Uveal Neoplasms decitabine 15.9417785578
MESH:D014604 Uveal Neoplasms Tretinoin 15.9416752155
MESH:D014820 Vitiligo Tretinoin 4.6416761959
MESH:D009396 Wilms Tumor Tretinoin 4.3916287080
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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