AutismKB 2.0

Annotation Detail for COX6A2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:COX6A2 ( COX6AH,COXVIAH )
Gene Full Name: cytochrome c oxidase subunit VIa polypeptide 2
Band: 16p11.2
Quick LinksEntrez ID:1339; OMIM: 602009; Uniprot ID:CX6A2_HUMAN; ENSEMBL ID: ENSG00000156885; HGNC ID: 2279
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa05016Huntington's disease
hsa05010Alzheimer's disease
hsa05012Parkinson's disease
hsa00190Oxidative phosphorylation
hsa01100Metabolic pathways
hsa04260Cardiac muscle contraction
No data
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of COX6A2 mRNAaffects expression 16483693
D000968 Antimycin A Antimycin A results in increased expression of COX6A2 mRNAincreases expression 19304788
D001151 Arsenic Arsenic affects the expression of COX6A2 mRNAaffects expression 18315880
D001151 Arsenic Arsenic results in increased expression of COX6A2 mRNAincreases expression 18315880
C006632 arsenic trioxide arsenic trioxide results in decreased expression of COX6A2 mRNAdecreases expression 19422848
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of COX6A2 mRNAdecreases expression 20106945
C055494 caffeic acid phenethyl ester [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of COX6A2 mRNAaffects cotreatment|decreases expression 20360939
D002330 Carmustine Carmustine results in decreased expression of COX6A2 mRNAdecreases expression 15980968
D016572 Cyclosporine Cyclosporine results in decreased expression of COX6A2 mRNAdecreases expression 20106945
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of COX6A2 mRNAaffects cotreatment|decreases expression 20360939
D000431 Ethanol Ethanol results in decreased expression of COX6A2 mRNAdecreases expression 15353170
D012402 Rotenone Rotenone results in increased expression of COX6A2 mRNAincreases expression 19304788
C017947 sodium arsenite sodium arsenite results in increased expression of COX6A2 mRNAincreases expression 16014739
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of COX6A2 mRNAdecreases expression 20399798
D014212 Tretinoin Tretinoin results in increased expression of COX6A2 mRNAincreases expression 16788091
16604517
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Ethanol 8.7517676605 18926900
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.7511752688 15322242 14514962
MESH:D000138 Acidosis Ammonium Chloride 10.7518287403
MESH:D000138 Acidosis Ethanol 10.7511192467
MESH:D000230 Adenocarcinoma arsenic trioxide 4.3911798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.3920127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 6.736695378
MESH:D000236 Adenoma Diethylnitrosamine 6.736695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 10.3317620307 19052882 19061943 16434500 17162532 18056438
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 10.3316835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.8015276417
MESH:D018246 Adrenocortical Adenoma Arsenic 14.1217306315
MESH:D018246 Adrenocortical Adenoma sodium arsenite 14.1217306315 16712894
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 5.4215451039 15451040
MESH:D000505 Alopecia Tretinoin 3.6615955085
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.0011748828
MESH:D000853 Anophthalmos Ethanol 4.8915513904
MESH:D001008 Anxiety Disorders Ethanol 4.0511141031
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.1519183758
MESH:D020261 Arsenic Poisoning Arsenic 2.8816835338 12569548 16251483 18414634
MESH:D001169 Arthritis, Experimental Tretinoin 3.1116412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2716292516
MESH:D001249 Asthma Tretinoin 2.3616456186
MESH:D050197 Atherosclerosis Arsenic 3.2812928151 19371607
MESH:D001471 Barrett Esophagus Tretinoin 4.4716935849
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 15.6716206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 15.6712125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 15.6716206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.8915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.8015746008
MESH:D001932 Brain Neoplasms Carmustine 4.4416187019
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.9320146248 17474063
MESH:D001943 Breast Neoplasms Diethylnitrosamine 1.9317474063
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9320435547
MESH:D001943 Breast Neoplasms Tretinoin 1.9316873071 16443354 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.6716813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.3911589617
MESH:D002056 Burns Ethanol 4.7216374292
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8416835633
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.6217687452 15504454
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.2616168501
MESH:D006528 Carcinoma, Hepatocellular Arsenic 11.5217306315 16507464
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 11.5215073043 16217749 11135700 14691202 15553829
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 11.5219418558 17173139 16807293 17978847 19822196 19539802 18785209 18393292 20084675 21159647 3581430 16569478 19394651 20524982 19335982 11831363 18665156 20727157 18978308 19052882 19519916 19171122 16681979 16935385 18691550 18506893 18056438 17761372 20432363 20007298 20935162 3084413 18971187 19208518 10737359 16328049 17428255 20214788 16878318 16502159 17162532 18210153 20514400 16288022 16540662 19701751 18788625 16779866 17055752 17138121 10672840 16698587 20101231 16830150 20512989 19107877 19919837 19383236 18494052
MESH:D006528 Carcinoma, Hepatocellular Ethanol 11.5215763234 15289165 18788625
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 11.5217306315 16507464 15276417
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 11.521917145
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.9719014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.1712490120
MESH:D002294 Carcinoma, Squamous Cell Arsenic 10.9317687452 18922899 15504454
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 10.9320419170
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 10.9318572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 10.9316051514 16096774
MESH:D002295 Carcinoma, Transitional Cell Arsenic 4.1318640142
MESH:D006332 Cardiomegaly Ethanol 6.9419332462
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.9418850075 18670907 16120746
MESH:D002318 Cardiovascular Diseases Arsenic 3.4815738583 19152805 17938729
MESH:D002340 Carotid Artery Diseases Arsenic 4.3618022660 16973168
MESH:D002386 Cataract Tretinoin 3.1217460283
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 11.4012371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 11.4017174075 7505956 2727394 21159647
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 11.4019524636 20056578
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.6716129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 9.4919052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 9.4916835633
MESH:D002779 Cholestasis Cyclosporine 2.9519486331
MESH:D002822 Choriocarcinoma Tretinoin 5.2616461808
MESH:D002971 Cleft Lip Ethanol 3.6115513904
MESH:D002972 Cleft Palate Ethanol 9.9715513904
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 9.9712621046 8697196 15668235 15340226 16354765
MESH:D002972 Cleft Palate Tretinoin 9.979407595
MESH:D003092 Colitis Tretinoin 3.7817035595
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.1117141729 14669216
MESH:D023903 Coronary Restenosis arsenic trioxide 4.2512609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 5.4710525206
MESH:D019465 Craniofacial Abnormalities Ethanol 5.4715451040 15451039 15513904 19302082 11873399 10194807 11198716
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 5.4720055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 5.4714991402 10589399 9664655 16925845 9211117 17551590 9125849 8800419 9224671 9142499
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.1515213294
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.2620387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.2617107852
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 6.3519107877
MESH:D056486 Drug-Induced Liver Injury Ethanol 6.3511566570
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 6.3520420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.8011462148
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.4312711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 12.2715322242 18230668 16714409
MESH:D004489 Edema, Cardiac Tretinoin 12.2718230668
MESH:D016889 Endometrial Neoplasms Tretinoin 3.1416569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.079294722 10568697
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.2116302075
MESH:D004938 Esophageal Neoplasms arsenic trioxide 7.3812903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 7.3816530937
MESH:D004938 Esophageal Neoplasms Ethanol 7.3816704527
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.9711564622
MESH:D005124 Eye Abnormalities Tretinoin 8.9716938888 9664655
MESH:D005234 Fatty Liver arsenic trioxide 19.2815073043
MESH:D005234 Fatty Liver Cyclosporine 19.2819224547
MESH:D005234 Fatty Liver Diethylnitrosamine 19.2821071580 20387270
MESH:D005234 Fatty Liver Ethanol 19.2816409862 19236843 18620774
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.7617920746
MESH:D005310 Fetal Alcohol Syndrome Ethanol 5.3816946407 15451040 15513904 10194807
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5311858732
MESH:D005355 Fibrosis Cyclosporine 15.1612639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 15.1620067830
MESH:D005355 Fibrosis Tretinoin 15.1617994277
MESH:D005534 Foot Diseases Arsenic 5.666392382
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.3316904648
MESH:D005756 Gastritis Ethanol 4.7915046732
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.7616452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.308708960
MESH:D005909 Glioblastoma Carmustine 7.5716187019
MESH:D005909 Glioblastoma Tretinoin 7.5717312396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.6910696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.2216096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.2616084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 11.2520471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 11.2510048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 11.259664655 14991402
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.5015720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3911000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.9615340226 16120746 12621046
MESH:D006689 Hodgkin Disease sodium arsenite 3.2012676792
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.1416959395 8697196 18606429 15340226 16354765
MESH:D006930 Hyperalgesia Ethanol 8.1418783367
MESH:D006930 Hyperalgesia Tretinoin 8.1416870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.6416778211
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.5117050553
MESH:D006973 Hypertension Arsenic 8.6916076760 11953799 9931084
MESH:D006973 Hypertension Cyclosporine 8.6910903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.6918670907 18850075
MESH:D006987 Hypesthesia Arsenic 5.6616093927
MESH:D007248 Infertility, Male sodium arsenite 3.0215346721 12646999
MESH:D007249 Inflammation Diethylnitrosamine 4.9818785209
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.9812878042 12200463
MESH:D007410 Intestinal Diseases Tretinoin 3.8417994277
MESH:D007414 Intestinal Neoplasms caffeic acid phenethyl ester 4.6410783313
MESH:D007569 Jaw Abnormalities Ethanol 17.5115513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 17.5116580747
MESH:D007569 Jaw Abnormalities Tretinoin 17.5115992940 17551590
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.5415604871
MESH:D007642 Keratosis Arsenic 5.0712749816 16930632
MESH:D007674 Kidney Diseases caffeic acid phenethyl ester 10.3615369732
MESH:D007674 Kidney Diseases Cyclosporine 10.368314463 10903974 18776723
MESH:D007674 Kidney Diseases sodium arsenite 10.3620008137
MESH:D007680 Kidney Neoplasms Cyclosporine 2.7812371664
MESH:D007859 Learning Disorders Ethanol 4.2815451040
MESH:D007938 Leukemia arsenic trioxide 6.4315070760
MESH:D007938 Leukemia Tretinoin 6.4317143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.8517077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.3916972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.4714633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 9.6619077051
MESH:D007951 Leukemia, Myeloid Tretinoin 9.6616482212 19285840 16932348
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.9119850784 17050201 16467208 16968895 20471514
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 3.9117596541 19850784 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 18.5117339181
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 18.5117649720 17107899 12712474 17217047 19075265 15748426 19642359 16966277 19035177 19225113 9834237 15622746 15213294 16112521 16891316 15336539 17712046 12018890 16823087 11468182 12679006 11161223 16331271 17869043 16330433
MESH:D015473 Leukemia, Promyelocytic, Acute caffeic acid phenethyl ester 18.5116766008
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 18.5116935935 15748426 19029980 17368321 19225113 16140955 17649720 16331271 17301526 17712046 16823087 16766008 17294898 9834237 17107899 17506722 16891316 12679006 16788101 17217047 17339181 17361223 19075265 19035177 19642359
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.4216882451
MESH:D017880 Limb Deformities, Congenital Ethanol 8.4517676605
MESH:D017880 Limb Deformities, Congenital Tretinoin 8.459224671
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.9120032147 19638242 18522880 18665156 18407596
MESH:D008103 Liver Cirrhosis Ethanol 6.9115289165
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 5.1818295389
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 3.5618166357
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.5612878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 3.5618397230 16248980
MESH:D008107 Liver Diseases Arsenic 4.2811134558
MESH:D008107 Liver Diseases Diethylnitrosamine 4.2817034775
MESH:D008108 Liver Diseases, Alcoholic Ethanol 4.7217207112 17347304
MESH:D008113 Liver Neoplasms Arsenic 18.2516368122
MESH:D008113 Liver Neoplasms arsenic trioxide 18.2514682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 18.2521137059 20195826
MESH:D008113 Liver Neoplasms Diethylnitrosamine 18.2519833225 20583210 18978307 19850985 19642983 19996281 20118626 19255062 2422723 20434301 21047994 15885732 21167192 12771043 21071580 18977376 20501860 21278145 20405173 19499222 2862719 19812893 10737359 18644402 20492335 18648771 19551842 20452335 19090486 19426721 19256749 19254457 9163691 19294768 18754104 20101389 19638242 19427195 15175105 20137499 12112319 16942905 19073162 19690152
MESH:D008113 Liver Neoplasms sodium arsenite 18.2515276417 16712894
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 18.2516984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 10.0020377131
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 10.0018253720 18282651 18164116 16267830 18079962 17854601 19539802 19009564 18544905 21159647 18775883 17174075 19126423 18308698 3124819 17942915 16842330 9362446 19004024 2563599 18093689 19519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 10.0012151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.3915213294
MESH:D008171 Lung Diseases sodium arsenite 3.2119095001
MESH:D008175 Lung Neoplasms Arsenic 8.6417306315 19168569 17976673
MESH:D008175 Lung Neoplasms arsenic trioxide 8.6411798837 19825857
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 8.6420464547 18569708 18816296 6695378 18520028 20135361 20869020 17053015 20064080
MESH:D008175 Lung Neoplasms Diethylnitrosamine 8.646695378 21163286 20512841 20970405
MESH:D008175 Lung Neoplasms sodium arsenite 8.6417306315 16712894 17077188 19931552 15276417
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 8.6419555203 11884234
MESH:D008527 Medulloblastoma Tretinoin 2.8017453147
MESH:D008545 Melanoma Carmustine 5.2812393984
MESH:D008545 Melanoma sodium arsenite 5.2819082730 16487513
MESH:D008545 Melanoma Tretinoin 5.2816752155
MESH:D008569 Memory Disorders Ethanol 4.2518411066 15451040
MESH:D008591 Meningomyelocele Tretinoin 4.5016940565
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.8816801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.2316381670
MESH:D009101 Multiple Myeloma arsenic trioxide 3.1419417148 19549372 15949261 14977855 11468182
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.7718349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 7.4916105982 16882451
MESH:D009190 Myelodysplastic Syndromes Tretinoin 7.4917596541
MESH:D017202 Myocardial Ischemia Arsenic 9.1515371236
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 9.1512213967
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.0216624393
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.593581430 9029167
MESH:D009369 Neoplasms Benzo(a)pyrene 8.4211141357
MESH:D009369 Neoplasms sodium arsenite 8.4211559025
MESH:D009369 Neoplasms Tretinoin 8.4216946489 16594593
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.7420056578
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.5417954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.3318481113 19348381
MESH:D009410 Nerve Degeneration Rotenone 3.9215790535 17356569 18619942
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.7314600291
MESH:D009421 Nervous System Malformations Tretinoin 9.739125849
MESH:D009436 Neural Tube Defects Arsenic 17.6416620997
MESH:D009436 Neural Tube Defects arsenic trioxide 17.6410525206
MESH:D009436 Neural Tube Defects sodium arsenite 17.6412854658
MESH:D009436 Neural Tube Defects Tretinoin 17.649142499
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.3920387270
MESH:D020078 Neurogenic Inflammation Arsenic 4.4317056641
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.2120387270
MESH:D010051 Ovarian Neoplasms Arsenic 11.4517306315
MESH:D010051 Ovarian Neoplasms arsenic trioxide 11.4516624393 19769630 12452020
MESH:D010051 Ovarian Neoplasms sodium arsenite 11.4515276417 17306315
MESH:D010051 Ovarian Neoplasms Tretinoin 11.4516936753
MESH:D010146 Pain Tretinoin 2.9516870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 12.5115580305
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 12.5116540662
MESH:D010190 Pancreatic Neoplasms Ethanol 12.5112384795
MESH:D010190 Pancreatic Neoplasms Tretinoin 12.5115976015
MESH:D010235 Paraganglioma arsenic trioxide 4.2219927285
MESH:D010300 Parkinson Disease Rotenone 2.9915451049 16140633 18619942 16412576 11535288 18191903 11445065 19232380 19114014
MESH:D020734 Parkinsonian Disorders Rotenone 4.1315574749 15795934 18197244 15927086
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.3512520081
MESH:D010523 Peripheral Nervous System Diseases Arsenic 4.2416093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 5.076392382 16905509 15371236
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.6218163543
MESH:D011230 Precancerous Conditions Cyclosporine 9.1012371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 9.102563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.2711118676 11896295 11222880 11399792
MESH:D011471 Prostatic Neoplasms Arsenic 2.0816140617
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.0819131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.0817292933
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.0816039940
MESH:D011507 Proteinuria Arsenic 9.4821343184
MESH:D011507 Proteinuria Tretinoin 9.4816636307
MESH:D011565 Psoriasis Cyclosporine 2.2416882103
MESH:D011625 Pterygium Tretinoin 4.8816723453
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.9018990726
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.1616283617 16116481
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.0216646077
MESH:D012640 Seizures Ethanol 3.209754883
MESH:D012871 Skin Diseases Arsenic 2.7617548696 18709164 19834688 17453740 16353154 17938729 17050553 6392382 16759981 16702368 15952646
MESH:D012878 Skin Neoplasms Arsenic 18.1917976673 19538983 17029826 15504454 16251483 17050553
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 18.1910029692 19755658
MESH:D012878 Skin Neoplasms sodium arsenite 18.1919524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 18.1916192470
MESH:D012878 Skin Neoplasms Tretinoin 18.1916467112
MESH:D016135 Spinal Dysraphism sodium arsenite 3.8412854658
MESH:D013274 Stomach Neoplasms arsenic trioxide 6.4617007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 6.462093021 20155912
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 6.4618456281
MESH:D013274 Stomach Neoplasms Ethanol 6.4618456281
MESH:D013274 Stomach Neoplasms Tretinoin 6.4617261132
MESH:D013276 Stomach Ulcer Ethanol 3.5811906479 9211565 17918041 17189318 16755016 9562338
MESH:D013375 Substance Withdrawal Syndrome Ethanol 4.309754883
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.0012697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 12.2219014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 12.227505956
MESH:D013964 Thyroid Neoplasms Tretinoin 12.2216026305 17045167
MESH:D014062 Tongue Neoplasms Tretinoin 3.8416051514
MESH:D016171 Torsades de Pointes arsenic trioxide 4.0415213294
MESH:D014376 Tuberculosis Tretinoin 3.2616040207
MESH:D001749 Urinary Bladder Neoplasms Arsenic 12.1219429237 19322015 18640142 15987713 17306315 11144890 17976673
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 12.1220435036 11780464 12973940 12845720
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 12.1217053015
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 12.1217306315 16712894 11723127 16452187
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 9.5811813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 9.5816129372
MESH:D014604 Uveal Neoplasms Tretinoin 4.7116752155
MESH:D014605 Uveitis Cyclosporine 4.081336536
MESH:D014652 Vascular Diseases Arsenic 12.1317056641
MESH:D014652 Vascular Diseases sodium arsenite 12.1317056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.6912125929
MESH:D014820 Vitiligo Tretinoin 4.1216761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.3515886252
MESH:D009396 Wilms Tumor Tretinoin 4.0216287080
MESH:D014985 Xerophthalmia Cyclosporine 4.5417120751
Pathway ID Pathway Name
KEGG:05010 Alzheimer's disease
KEGG:04260 Cardiac muscle contraction
KEGG:05016 Huntington's disease
KEGG:01100 Metabolic pathways
KEGG:00190 Oxidative phosphorylation
KEGG:05012 Parkinson's disease
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB02659 - Cholic Acid
DB04464 - N-Formylmethionine
No data
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved