AutismKB 2.0

Annotation Detail for FAM173B


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Basic Information Top
Gene Symbol:FAM173B ( FLJ20667 )
Gene Full Name: family with sequence similarity 173, member B
Band: 5p15.2
Quick LinksEntrez ID:134145; OMIM: NA; Uniprot ID:F173B_HUMAN; ENSEMBL ID: ENSG00000150756; HGNC ID: 27029
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of FAM173B mRNAaffects expression 17562736
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of FAM173B mRNAdecreases expression 20018196
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of FAM173B mRNAaffects expression 17555576
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.8117505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8914692618
MESH:D000799 Angioedema Acetaminophen 4.7110982225
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 4.1211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.9115885639
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.8110977129
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 3.0120889678
MESH:D002779 Cholestasis Ethinyl Estradiol 3.2017110522 17681005 11677210 16105132 17333356 16919318 15861022
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6816177239 17522070 16109766 12392966 19085960 19420014 11743745 11421492 14725611 12958197 16081117 15619225 19416960 12153990 15968718 2444490 16227642 12540782 17906064 14550746 10915739 17562736 18713872 19370779 11287661 19923254 18071297 10774834 11834606 16485898 14986274 10663392 11461765 19164858 12705907 16393943 16781746 12594235 11739529 11529661 19739265
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.9619426721
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.7712538720
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1520426865
MESH:D005234 Fatty Liver Ethinyl Estradiol 3.2915345470
MESH:D005756 Gastritis Acetaminophen 4.5416983495
MESH:D006930 Hyperalgesia Acetaminophen 3.0616870215
MESH:D007021 Hypospadias Ethinyl Estradiol 4.4616945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.9912013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.7617937319
MESH:D007674 Kidney Diseases Acetaminophen 2.4215629191 12587719
MESH:D008107 Liver Diseases Acetaminophen 1.7116611625 19784758 12587719 19014921 11587558 12969438 16610002 19460945
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6816871587 17185352
MESH:D008546 Melanoma, Experimental Acetaminophen 4.2219513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2618514411
MESH:D010146 Pain Acetaminophen 2.7716870215
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.2211578682
MESH:D011537 Pruritus Ethinyl Estradiol 4.0516919318 15861022
MESH:D013088 Spermatocele Ethinyl Estradiol 4.8116709447
MESH:D019851 Thrombophilia Ethinyl Estradiol 4.1511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.5715669648
MESH:D014581 Urticaria Acetaminophen 3.5010982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.8814692618
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 4.0214671159 15869587
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018