AutismKB 2.0

Annotation Detail for CREBBP


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Basic Information Top
Gene Symbol:CREBBP ( CBP,KAT3A,RSTS )
Gene Full Name: CREB binding protein
Band: 16p13.3
Quick LinksEntrez ID:1387; OMIM: 600140; Uniprot ID:CBP_HUMAN; ENSEMBL ID: ENSG00000005339; HGNC ID: 2348
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04916Melanogenesis
hsa04720Long-term potentiation
hsa04310Wnt signaling pathway
hsa05016Huntington's disease
hsa04630Jak-STAT signaling pathway
hsa04330Notch signaling pathway
hsa04350TGF-beta signaling pathway
hsa05211Renal cell carcinoma
hsa04110Cell cycle
hsa04520Adherens junction
hsa05215Prostate cancer
hsa05200Pathways in cancer
Pathway IDPathway Name
Gene Expression
Metabolism of lipids and lipoproteins
Pathway IDPathway Name
200030HIF-2-alpha transcription factor network
200070Signaling events mediated by HDAC Class I
200002Regulation of nuclear SMAD2/3 signaling
200027E2F transcription factor network
200130C-MYB transcription factor network
200156Signaling events mediated by Stem cell factor receptor (c-Kit)
200020Signaling events mediated by HDAC Class III
200120FOXM1 transcription factor network
200065Signaling events mediated by TCPTP
200091FoxO family signaling
200172HIF-1-alpha transcription factor network
200175p53 pathway
200077Glucocorticoid receptor regulatory network
200076Role of Calcineurin-dependent NFAT signaling in lymphocytes
200147Hedgehog signaling events mediated by Gli proteins
200110IFN-gamma pathway
200045Validated targets of C-MYC transcriptional activation
200101Direct p53 effectors
200102Regulation of Androgen receptor activity
200191Regulation of retinoblastoma protein
200196Notch-mediated HES/HEY network
200197IL12 signaling mediated by STAT4
200194FOXA1 transcription factor network
200052Presenilin action in Notch and Wnt signaling
Pathway IDPathway Name
P00026Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
P00052TGF-beta signaling pathway
P00025Hedgehog signaling pathway
P00029Huntington disease
P00030Hypoxia response via HIF activation
P00059p53 pathway
P00055Transcription regulation by bZIP transcription factor
P00057Wnt signaling pathway
Pathway IDPathway Name
500905Notch-HLH transcription pathway
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1831Prostate cancer
1977Rheumatism
1993Esophagus cancer
2011Leukoencephalopathy
2051Leukemia
2066Lung cancer
2151Neuroblastoma
2163Mucopolysaccharidosis
2232Aseptic necrosis of bone
No data
No data
Desease Name
Rubenstein-Taybi syndrome
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of CREBBP mRNAaffects expression 21346803
C027576 4-hydroxy-2-nonenal CREBBP protein inhibits the reaction [4-hydroxy-2-nonenal results in decreased expression of BDNF mRNA]decreases expression|decreases reaction 16337876
D000082 Acetaminophen Acetaminophen affects the expression of CREBBP mRNAaffects expression 17562736
D000171 Acrolein CREBBP protein inhibits the reaction [Acrolein results in decreased expression of BDNF mRNA]decreases expression|decreases reaction 16337876
D000242 Cyclic AMP CREBBP protein promotes the reaction [Cyclic AMP results in increased activity of ESR1 protein]increases activity|increases reaction 20360387
D000450 Aldosterone Aldosterone promotes the reaction [NR3C2 protein binds to CREBBP protein]affects binding|increases reaction 19966502
D000450 Aldosterone Aldosterone results in increased expression of and results in increased localization of CREBBP proteinincreases expression|increases localization 19966502
C095512 alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [IL6 protein results in decreased expression of CREBBP protein]decreases expression|decreases reaction 15378487
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CREBBP mRNAaffects expression 16483693
D000728 Androgens CREBBP protein promotes the reaction [Androgens results in increased activity of AR protein]increases activity|increases reaction 15378487
C006632 arsenic trioxide arsenic trioxide promotes the reaction [CREBBP protein binds to CDKN1A promoter]affects binding|increases reaction 18822310
C006632 arsenic trioxide arsenic trioxide promotes the reaction [[CREBBP protein binds to CDKN1A promoter] which results in increased expression of CDKN1A mRNA]affects binding|increases expression|increases reaction 18822310
C006632 arsenic trioxide arsenic trioxide promotes the reaction [CREBBP protein results in increased expression of VCP mRNA]increases expression|increases reaction 18822310
D001241 Aspirin Aspirin results in increased expression of CREBBP mRNAincreases expression 11906190
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of CREBBP mRNAdecreases expression 19150397
D001629 Bezafibrate Bezafibrate affects the reaction [PPARA protein binds to CREBBP protein]affects binding|affects reaction 19263263
C053541 bicalutamide bicalutamide inhibits the reaction [Metribolone results in decreased expression of CREBBP protein]decreases expression|decreases reaction 15378487
D002166 Camptothecin Camptothecin inhibits the reaction [RELA protein binds to CREBBP protein]affects binding|decreases reaction 13679428
D002166 Camptothecin Camptothecin promotes the reaction [TP53 protein binds to CREBBP protein]affects binding|increases reaction 13679428
D002166 Camptothecin pifithrin inhibits the reaction [Camptothecin inhibits the reaction [RELA protein binds to CREBBP protein]]affects binding|decreases reaction 13679428
D002166 Camptothecin pifithrin inhibits the reaction [Camptothecin promotes the reaction [TP53 protein binds to CREBBP protein]]affects binding|decreases reaction|increases reaction 13679428
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of CREBBP mRNAincreases expression 18395914
D002251 Carbon Tetrachloride oxymatrine inhibits the reaction [Carbon Tetrachloride results in increased expression of CREBBP mRNA]decreases reaction|increases expression 18395914
D003474 Curcumin Curcumin results in decreased expression of CREBBPdecreases expression 18462866
D017373 Cyproterone Acetate [Cyproterone Acetate binds to AR protein] promotes the reaction [CREBBP protein binds to KLK3 enhancer]affects binding|increases reaction 15308689
D017373 Cyproterone Acetate [Cyproterone Acetate binds to AR protein] promotes the reaction [CREBBP protein binds to KLK3 promoter]affects binding|increases reaction 15308689
D002945 Cisplatin Cisplatin results in decreased expression of CREBBP proteindecreases expression 17498666
D002117 Calcitriol Calcitriol affects the localization of CREBBP proteinaffects localization 15647825
D002117 Calcitriol Calcitriol promotes the reaction [CREBBP protein binds to SPP1 promoter]affects binding|increases reaction 15647825
D004317 Doxorubicin Doxorubicin promotes the reaction [CREBBP protein binds to ESR1 promoter]affects binding|increases reaction 19351845
D004317 Doxorubicin Doxorubicin promotes the reaction [TP53 protein binds to CREBBP protein]affects binding|increases reaction 19351845
D004317 Doxorubicin Doxorubicin results in decreased expression of CREBBP proteindecreases expression 17498666
D004365 Drugs, Chinese Herbal Drugs, Chinese Herbal promotes the reaction [CREBBP protein binds to KRT19 promoter]affects binding|increases reaction 17095596
C044101 endotoxin, Escherichia coli endotoxin, Escherichia coli results in decreased expression of CREBBP mRNAdecreases expression 15919760
D004958 Estradiol Estradiol promotes the reaction [CREBBP protein binds to ESR1 promoter]affects binding|increases reaction 19620290
D004958 Estradiol Estradiol promotes the reaction [CREBBP protein binds to IGF1 promoter]affects binding|increases reaction 17872375
D004958 Estradiol Estradiol promotes the reaction [CREBBP protein binds to PTGS2 promoter]affects binding|increases reaction 17872375
D004958 Estradiol Estradiol promotes the reaction [CREBBP protein binds to TTF1 promoter]affects binding|increases reaction 19698761
D004958 Estradiol Estradiol promotes the reaction [ESR1 protein binds to CREBBP protein binds to BRCA1 protein]affects binding|increases reaction 16417649
D004958 Estradiol Estradiol results in decreased expression of CREBBP mRNAdecreases expression 20068009
D019307 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Phenylephrine results in increased expression of CREBBP mRNA]decreases reaction|increases expression 11705990
C051890 irinotecan irinotecan analog results in decreased expression of CREBBP mRNAdecreases expression 18927307
C051890 irinotecan irinotecan metabolite results in decreased expression of CREBBP mRNAdecreases expression 15956246
C051890 irinotecan irinotecan results in decreased expression of CREBBP mRNAdecreases expression 15956246
D008070 Lipopolysaccharides Lipopolysaccharides results in decreased expression of CREBBP mRNAdecreases expression 15919760
16847310
D015741 Metribolone bicalutamide inhibits the reaction [Metribolone results in decreased expression of CREBBP protein]decreases expression|decreases reaction 15378487
D015741 Metribolone Metribolone inhibits the reaction [CREBBP protein results in increased activity of AR protein]decreases reaction|increases activity 11981028
D015741 Metribolone Metribolone results in decreased expression of CREBBP mRNAdecreases expression 15378487
D015741 Metribolone Metribolone results in decreased expression of CREBBP proteindecreases expression 15378487
C517398 MF101 extract MF101 extract promotes the reaction [CREBBP protein binds to KRT19 promoter]affects binding|increases reaction 17095596
D015735 Mifepristone [Mifepristone binds to AR protein] promotes the reaction [CREBBP protein binds to KLK3 enhancer]affects binding|increases reaction 15308689
D015735 Mifepristone [Mifepristone binds to AR protein] promotes the reaction [CREBBP protein binds to KLK3 promoter]affects binding|increases reaction 15308689
C044387 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [HIF1A protein binds to CREBBP protein]affects binding|decreases reaction 16579968
D019787 Linoleic Acid Linoleic Acid affects the reaction [PPARA protein binds to CREBBP protein]affects binding|affects reaction 19263263
D019319 Okadaic Acid Okadaic Acid results in increased phosphorylation of CREBBP proteinincreases phosphorylation 16059639
C037573 oxymatrine oxymatrine inhibits the reaction [Carbon Tetrachloride results in increased expression of CREBBP mRNA]decreases reaction|increases expression 18395914
C093973 PD 98059 PD 98059 inhibits the reaction [Phenylephrine results in increased expression of CREBBP mRNA]decreases reaction|increases expression 11705990
C093973 PD 98059 PD 98059 results in decreased expression of CREBBP mRNAdecreases expression 11705990
D010656 Phenylephrine CREBBP protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]affects reaction|increases expression 11705990
D010656 Phenylephrine CREBBP protein results in increased susceptibility to Phenylephrineincreases response to substance 12477714
D010656 Phenylephrine Phenylephrine promotes the reaction [CREB1 protein binds to CREBBP protein]affects binding|increases reaction 15522277
D010656 Phenylephrine Phenylephrine promotes the reaction [NR3C2 protein binds to CREBBP protein]affects binding|increases reaction 19966502
D010656 Phenylephrine [Phenylephrine results in increased activity of CREBBP protein] which results in increased expression of NPPA proteinincreases activity|increases expression 12477714
D010656 Phenylephrine Phenylephrine results in increased expression of and results in increased localization of CREBBP proteinincreases expression|increases localization 19966502
D010656 Phenylephrine Phenylephrine results in increased phosphorylation of and results in increased activity of CREBBP proteinincreases activity|increases phosphorylation 15006641
D010656 Phenylephrine 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Phenylephrine results in increased expression of CREBBP mRNA]decreases reaction|increases expression 11705990
D010656 Phenylephrine MAPK1 protein promotes the reaction [Phenylephrine results in increased expression of CREBBP mRNA]increases expression|increases reaction 11705990
D010656 Phenylephrine PD 98059 inhibits the reaction [Phenylephrine results in increased expression of CREBBP mRNA]decreases reaction|increases expression 11705990
D010656 Phenylephrine Phenylephrine results in increased expression of CREBBP mRNAincreases expression 11705990
D010656 Phenylephrine Prazosin inhibits the reaction [Phenylephrine results in increased expression of CREBBP mRNA]decreases reaction|increases expression 11705990
C121565 pifithrin pifithrin inhibits the reaction [Camptothecin inhibits the reaction [RELA protein binds to CREBBP protein]]affects binding|decreases reaction 13679428
C121565 pifithrin pifithrin inhibits the reaction [Camptothecin promotes the reaction [TP53 protein binds to CREBBP protein]]affects binding|decreases reaction|increases reaction 13679428
C121565 pifithrin pifithrin promotes the reaction [RELA protein binds to CREBBP protein]affects binding|increases reaction 13679428
C006253 pirinixic acid pirinixic acid affects the reaction [PPARA protein binds to CREBBP protein]affects binding|affects reaction 19263263
D011224 Prazosin Prazosin inhibits the reaction [Phenylephrine results in increased expression of CREBBP mRNA]decreases reaction|increases expression 11705990
D011794 Quercetin Quercetin results in increased expression of CREBBP mRNAincreases expression 14715546
D011794 Quercetin Quercetin inhibits the reaction [TNF protein promotes the reaction [CREBBP protein binds to CXCL10 promoter]]affects binding|decreases reaction|increases reaction 17449583
D011794 Quercetin Quercetin inhibits the reaction [TNF protein promotes the reaction [CREBBP protein binds to CXCL2 promoter]]affects binding|decreases reaction|increases reaction 17449583
D011794 Quercetin Quercetin affects the activity of CREBBP modified formaffects activity 19423323
D020849 Raloxifene Raloxifene promotes the reaction [CREBBP protein binds to IGF1 promoter]affects binding|increases reaction 17872375
D020849 Raloxifene Raloxifene promotes the reaction [CREBBP protein binds to PTGS2 promoter]affects binding|increases reaction 17872375
C059514 resveratrol BCL2 protein inhibits the reaction [resveratrol promotes the reaction [PML protein binds to CREBBP protein]]affects binding|decreases reaction|increases reaction 19631782
C059514 resveratrol resveratrol promotes the reaction [PML protein binds to CREBBP protein]affects binding|increases reaction 19631782
C059514 resveratrol resveratrol promotes the reaction [TP53 protein binds to PML protein binds to CREBBP protein]affects binding|increases reaction 19631782
C059514 resveratrol resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to RELA protein]]affects binding|decreases reaction|increases reaction 16474181
D012643 Selenium Selenium results in decreased expression of CREBBP mRNAdecreases expression 19244175
C017947 sodium arsenite sodium arsenite results in decreased expression of CREBBP mRNAdecreases expression 12377979
C017947 sodium arsenite sodium arsenite results in increased expression of CREBBP mRNAincreases expression 19822182
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin promotes the reaction [CREBBP protein binds to CYP1A1 promoter]affects binding|increases reaction 15964790
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of CREBBP mRNAincreases expression 19465110
D013755 Tetradecanoylphorbol Acetate resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to RELA protein]]affects binding|decreases reaction|increases reaction 16474181
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to RELA protein]affects binding|increases reaction 16474181
D014212 Tretinoin Tretinoin inhibits the reaction [[CREBBP protein binds to MAPK3 promoter] which affects the expression of MAPK3 mRNA]affects binding|affects expression|decreases reaction 16050810
D014212 Tretinoin Tretinoin promotes the reaction [CREBBP protein binds to HAS2 promoter]affects binding|increases reaction 17307735
D014212 Tretinoin Tretinoin promotes the reaction [CREBBP protein binds to PDK4 promoter]affects binding|increases reaction 16757381
D014212 Tretinoin Tretinoin promotes the reaction [CREBBP protein binds to RARA protein]affects binding|increases reaction 16417649
D014212 Tretinoin Tretinoin inhibits the reaction [CREBBP protein binds to RETN promoter]affects binding|decreases reaction 15047602
C012589 trichostatin A trichostatin A promotes the reaction [CREBBP protein binds to PDK4 promoter]affects binding|increases reaction 16757381
D014635 Valproic Acid Valproic Acid results in decreased expression of CREBBP mRNAdecreases expression 19101580
D014810 Vitamin E Vitamin E results in decreased expression of CREBBP mRNAdecreases expression 19244175
C111237 vorinostat vorinostat promotes the reaction [PML protein binds to CREBBP protein]affects binding|increases reaction 19631782
C111237 vorinostat vorinostat promotes the reaction [TP53 protein binds to PML protein binds to CREBBP protein]affects binding|increases reaction 19631782
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 6.5415322242 14514962 11752688
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 6.548875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.4519490988
MESH:D000038 Abscess Drugs, Chinese Herbal 5.7615043669
MESH:D000138 Acidosis Ammonium Chloride 3.0218287403
MESH:D058186 Acute Kidney Injury Cisplatin 11.8817670903 12690470 15814532
MESH:D058186 Acute Kidney Injury pifithrin 11.8817670903
MESH:D058186 Acute Kidney Injury resveratrol 11.8816538975
MESH:D055371 Acute Lung Injury Acrolein 12.5220525806 21297076
MESH:D055371 Acute Lung Injury Lipopolysaccharides 12.5218653653 11850527
MESH:D055371 Acute Lung Injury pirinixic acid 12.5218653653
MESH:D000230 Adenocarcinoma arsenic trioxide 8.8211798837 19825857
MESH:D000230 Adenocarcinoma Cisplatin 8.8211798837 17638652
MESH:D000230 Adenocarcinoma Doxorubicin 8.8217418594
MESH:D000230 Adenocarcinoma Estradiol 8.8211473722
MESH:D000236 Adenoma resveratrol 2.9915688382
MESH:D018248 Adenoma, Liver Cell pirinixic acid 8.1216434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 8.1216835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.1515276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.3516712894 17306315
MESH:D000419 Albuminuria Doxorubicin 9.7621441931
MESH:D000419 Albuminuria Raloxifene 9.7617308373 17451421
MESH:D019973 Alcohol-Related Disorders Curcumin 4.5317887948
MESH:D000505 Alopecia Tretinoin 3.1815955085
MESH:D000544 Alzheimer Disease Acrolein 10.9414715435 17570602 15207723
MESH:D000544 Alzheimer Disease Androgens 10.9417182789 17917157
MESH:D000544 Alzheimer Disease Curcumin 10.9415590663
MESH:D000544 Alzheimer Disease Raloxifene 10.9415800139
MESH:D000544 Alzheimer Disease resveratrol 10.9416162502 16183991
MESH:D000550 Amblyopia Valproic Acid 4.6817688650
MESH:D000690 Amyotrophic Lateral Sclerosis 4-hydroxy-2-nonenal 3.7510965797
MESH:D000740 Anemia Drugs, Chinese Herbal 7.4817963324 15504547
MESH:D000740 Anemia Tetrachlorodibenzodioxin 7.4811748828
MESH:D000743 Anemia, Hemolytic Quercetin 3.7617084956
MESH:D000787 Angina Pectoris Drugs, Chinese Herbal 4.8711477813
MESH:D000799 Angioedema Acetaminophen 3.3010982225
MESH:D001004 Anus Diseases Drugs, Chinese Herbal 5.4215043669
MESH:D001008 Anxiety Disorders Valproic Acid 3.1417497229
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 3.6517460149
MESH:D001161 Arteriosclerosis Acrolein 4.4815014928
MESH:D001169 Arthritis, Experimental resveratrol 6.3517115116
MESH:D001169 Arthritis, Experimental Tretinoin 6.3516412693
MESH:D015210 Arthritis, Gouty Drugs, Chinese Herbal 5.2119655406
MESH:D001172 Arthritis, Rheumatoid Curcumin 4.2116807698
MESH:D001172 Arthritis, Rheumatoid Tretinoin 4.2116292516
MESH:D001249 Asthma Tretinoin 2.1616456186
MESH:D055963 Asthma, Aspirin-Induced Aspirin 4.2520485159 12372130
MESH:D001260 Ataxia Telangiectasia Quercetin 4.4415336622
MESH:D050197 Atherosclerosis Acrolein 9.2317363696 16126721 16037261
MESH:D050197 Atherosclerosis Curcumin 9.2318704882
MESH:D050197 Atherosclerosis resveratrol 9.2317967414 16873680
MESH:D001321 Autistic Disorder Acetaminophen 2.2018445737
MESH:D001321 Autistic Disorder Linoleic Acid 2.2018582451
MESH:D001321 Autistic Disorder Valproic Acid 2.2019460635 18177632 19232924 18558336 18775368 18316065 16609825 18985861 17688650 20603192 18940202 15238991 18396377 17157402 17507914
MESH:D001327 Autoimmune Diseases Curcumin 9.1219761891
MESH:D001327 Autoimmune Diseases Quercetin 9.1219761891
MESH:D001471 Barrett Esophagus Tretinoin 3.8916935849
MESH:D001714 Bipolar Disorder Valproic Acid 2.7817594078 20046352
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 18.0016206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 18.0019483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 18.0012125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 18.0016206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.2415340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 6.8215746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 6.828888407
MESH:D019046 Bone Marrow Neoplasms Cisplatin 10.2314601052
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 10.2314601052
MESH:D001862 Bone Resorption Drugs, Chinese Herbal 4.349881647
MESH:D001919 Bradycardia Phenylephrine 4.0115306635
MESH:D001930 Brain Injuries Raloxifene 3.9516580743
MESH:D002545 Brain Ischemia Curcumin 8.5416770732
MESH:D002545 Brain Ischemia resveratrol 8.5417600658
MESH:D001932 Brain Neoplasms Aspirin 12.1015481559
MESH:D001932 Brain Neoplasms Curcumin 12.1017596214
MESH:D001932 Brain Neoplasms Doxorubicin 12.1017150277
MESH:D001943 Breast Neoplasms Androgens 10.0517018787
MESH:D001943 Breast Neoplasms Aspirin 10.0515161893
MESH:D001943 Breast Neoplasms Calcitriol 10.0511237771
MESH:D001943 Breast Neoplasms Cisplatin 10.0519526202 18382427
MESH:D001943 Breast Neoplasms Curcumin 10.0518462866 19250217 16243823 18593918
MESH:D001943 Breast Neoplasms Doxorubicin 10.0519526202 17426702 15136595 18382427 15939500 15668708 16595493 18628466 18695136 16096432 16322301 17983394 16264153 16826403 16935488 18234424 15634643 16115903 15567936 15994142 17369602 11325840 15692762 15993339
MESH:D001943 Breast Neoplasms Estradiol 10.0512948864 14630087 18497071 17018787 17261762 17289903 19861407 16675129
MESH:D001943 Breast Neoplasms Quercetin 10.0518628248
MESH:D001943 Breast Neoplasms Raloxifene 10.0517440819 15572757 17261762 16912660 17242785 17595753 17893378 16837676 15775269 17049068 17952589 15758505
MESH:D001943 Breast Neoplasms resveratrol 10.0517534123 16393696 17651959
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 10.0520435547
MESH:D001943 Breast Neoplasms Tretinoin 10.0516166294 16443354 16873071
MESH:D001943 Breast Neoplasms vorinostat 10.0516144943
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.0516813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.8311589617
MESH:D002105 Cadmium Poisoning Quercetin 5.0016962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.9216111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 8.1915673190 16097048 15700767 18705752 15721981 16124888 16227642 16011737 3786805 10355542 16050911 16192424
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 8.1916050911
MESH:D002276 Carcinoid Tumor Doxorubicin 4.2616051944
MESH:D002277 Carcinoma Curcumin 6.8618593918
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 6.8616835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.6116168501
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 23.3716705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 23.373084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 23.3715553829 14691202 16217749 11135700 15073043
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 23.3718788625
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 23.3717982673
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 23.3716023760 18059187 17876044 16234567
MESH:D006528 Carcinoma, Hepatocellular Estradiol 23.3716924424
MESH:D006528 Carcinoma, Hepatocellular Quercetin 23.3719519916 12508355
MESH:D006528 Carcinoma, Hepatocellular resveratrol 23.3719321006 16227395
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 23.3716507464 17306315 15276417
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 23.371917145
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.0516675471
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 5.0616685392 12023789
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 5.0618414057
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.4317234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.3319014326
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 2.8916201981 1485588
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.6512490120
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 22.7211237771
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 22.7217066447 6189445 18337622
MESH:D002294 Carcinoma, Squamous Cell Curcumin 22.7218462866
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 22.726189445
MESH:D002294 Carcinoma, Squamous Cell resveratrol 22.7216227395
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 22.7218572023
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 22.7218922899
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 22.7216051514 16096774
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 3.6117572228
MESH:D006332 Cardiomegaly Phenylephrine 9.6211179087 17124262 17287366 15728586 16170337 11754973
MESH:D006332 Cardiomegaly Quercetin 9.6219794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 9.6216120746 18850075 18670907
MESH:D009202 Cardiomyopathies Doxorubicin 3.1617351982 17519947 17131338 17308081 16731534 16612575 16278810 15476868 15811867 17007740 16651473 16455267 15792986 16242529 18627295 17924179 15505089 17382496 17928571 17974986 17329180 16269455 16952015 16109756 16364871
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.7417334414 16243910
MESH:D002318 Cardiovascular Diseases Aldosterone 10.2211230374
MESH:D002318 Cardiovascular Diseases Raloxifene 10.2215775269
MESH:D002318 Cardiovascular Diseases resveratrol 10.2215458977
MESH:D002386 Cataract Acetaminophen 6.1110977129
MESH:D002386 Cataract Tretinoin 6.1117460283
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 12.896135515
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 12.8920889678
MESH:D002471 Cell Transformation, Neoplastic Estradiol 12.8918566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 12.8920056578 19524636
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.0516129372
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.4920734317
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.7116835633
MESH:D002779 Cholestasis pirinixic acid 2.4219176532
MESH:D002822 Choriocarcinoma Tretinoin 4.6116461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 4.9215340226 8697196 15668235 12621046 16354765
MESH:D002972 Cleft Palate Tretinoin 4.929407595
MESH:D003072 Cognition Disorders Raloxifene 4.0915800139
MESH:D003092 Colitis Curcumin 18.5616804969 18200517 16782535
MESH:D003092 Colitis resveratrol 18.5616474422
MESH:D003092 Colitis Selenium 18.5617936198
MESH:D003092 Colitis Tretinoin 18.5617035595
MESH:D003103 Coloboma Curcumin 4.0718809619
MESH:D003110 Colonic Neoplasms Aspirin 9.7112411196
MESH:D003110 Colonic Neoplasms Curcumin 9.7119359593 16340194
MESH:D003110 Colonic Neoplasms irinotecan 9.7117287894 17725105
MESH:D003110 Colonic Neoplasms Quercetin 9.7115741050 19056647 17191121 11134977 16640504 17148506 19440933
MESH:D003110 Colonic Neoplasms resveratrol 9.7116338953
MESH:D015179 Colorectal Neoplasms Acrolein 11.4617597105
MESH:D015179 Colorectal Neoplasms arsenic trioxide 11.4620501625
MESH:D015179 Colorectal Neoplasms Aspirin 11.4617047198
MESH:D015179 Colorectal Neoplasms Cisplatin 11.4615273666
MESH:D015179 Colorectal Neoplasms Doxorubicin 11.4618259882 18802399
MESH:D015179 Colorectal Neoplasms irinotecan 11.4618509181 18259882 16303861 16391804 17454858 17159606 15273666
MESH:D015179 Colorectal Neoplasms Quercetin 11.4618095365 18852136
MESH:D015179 Colorectal Neoplasms resveratrol 11.4616550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.6117141729 14669216
MESH:D016510 Corneal Neovascularization Curcumin 4.3718497527
MESH:D003327 Coronary Disease resveratrol 3.3916507316
MESH:D023903 Coronary Restenosis arsenic trioxide 3.6712609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 6.4710525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 6.4710048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 6.4716925845 9664655 10589399 14991402 17551590 8800419 9142499 9224671 9211117 9125849
MESH:D019465 Craniofacial Abnormalities Valproic Acid 6.4717688650 8888407 16575769
MESH:D019465 Craniofacial Abnormalities Vitamin E 6.4719769572
MESH:D016638 Critical Illness Androgens 5.5216670151
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.4918551238
MESH:D003556 Cystitis Acrolein 4.8512161096
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.6015213294
MESH:D003865 Depressive Disorder, Major Raloxifene 3.7117474826
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.1518249437
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 7.0919496084
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 7.0916873680
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 3.8718403477
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 3.8717107852
MESH:D003928 Diabetic Nephropathies Curcumin 17.7418204486
MESH:D003928 Diabetic Nephropathies Estradiol 17.7419279558
MESH:D003928 Diabetic Nephropathies Raloxifene 17.7417308373 17451421 15920148
MESH:D003928 Diabetic Nephropathies resveratrol 17.7416286809
MESH:D003967 Diarrhea vorinostat 4.0020479100
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 22.0521346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 22.0510774834 11287661 19164858 12958197 12392966 16227642 19420014 11834606 18713872 11529661 11743745 12705907 11739529 14986274 10663392 19739265 15619225 12153990 12594235 11461765 16081117 14550746 16177239 17906064 16393943 10915739 15968718 16781746 17562736 17522070 16485898 12540782 2444490 19416960 19370779 14725611 19923254 11421492 16109766 18071297 19085960
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 22.0521278145 6884620 3786805 2869522 9327722 11566570 6623471 19336974 16177239 3732212 10915739 7179309 7440962 15027814 15998439 10092053 4309450 19085960 17522070 7120509 16227642 15968718
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 22.0517416283
MESH:D056486 Drug-Induced Liver Injury Drugs, Chinese Herbal 22.0515027814
MESH:D056486 Drug-Induced Liver Injury Prazosin 22.0518071297
MESH:D056486 Drug-Induced Liver Injury Selenium 22.0515131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 22.0520420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 22.051733752 19641884
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.5519426721
MESH:D004362 Drug Toxicity Cisplatin 11.4212649298 15033597 19839026 12231392
MESH:D004362 Drug Toxicity Doxorubicin 11.4218602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 11.4211462148
MESH:D004381 Duodenal Ulcer Curcumin 3.5417351913
MESH:D004421 Dystonia Valproic Acid 3.551851702
MESH:C538011 Eales disease Vitamin E 4.169068938
MESH:D004487 Edema Aspirin 20.8717259670
MESH:D004487 Edema pirinixic acid 20.8712083418
MESH:D004487 Edema Raloxifene 20.8715860553
MESH:D004487 Edema resveratrol 20.878985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 20.8711000095 12711302
MESH:D004487 Edema Tetradecanoylphorbol Acetate 20.878113982 9599246 8273558 15177302 16716910 11698051 7812673
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.1215322242 16714409 18230668
MESH:D004489 Edema, Cardiac Tretinoin 10.1218230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 12.5715138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 12.5715845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 12.5717872969
MESH:D004701 Endocrine Gland Neoplasms trichostatin A 5.0919294695
MESH:D016889 Endometrial Neoplasms Doxorubicin 10.3617359293
MESH:D016889 Endometrial Neoplasms Estradiol 10.3618566989 11473722 19148513
MESH:D016889 Endometrial Neoplasms Tretinoin 10.3616569247
MESH:D004715 Endometriosis Mifepristone 7.6016134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 7.609294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.6118037988
MESH:D019446 Endotoxemia endotoxin, Escherichia coli 9.2718509659 17637181
MESH:D019446 Endotoxemia Lipopolysaccharides 9.2715328337 17637181 15821434
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.3217923197
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 3.6317275665 3659116
MESH:D004828 Epilepsies, Partial Valproic Acid 3.373922381 16628512
MESH:D004827 Epilepsy Valproic Acid 2.6418234410 20417680
MESH:D004832 Epilepsy, Absence Valproic Acid 3.146254150 7562514 6426943
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 3.777750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 3.533659116
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 6.3120426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 6.3112903497
MESH:D004938 Esophageal Neoplasms Cisplatin 6.3116481741 16785472 17638652 15464296 15173087
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.4811564622
MESH:D005124 Eye Abnormalities Tretinoin 7.489664655 16938888
MESH:D005221 Fatigue vorinostat 5.0620479100
MESH:D005234 Fatty Liver arsenic trioxide 24.5115073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 24.5115959796 61145 12795759 19224547 17595544 16239168 12631006 16045604
MESH:D005234 Fatty Liver Curcumin 24.5119297423
MESH:D005234 Fatty Liver pirinixic acid 24.5119236843 20131406
MESH:D005234 Fatty Liver Raloxifene 24.5117473493
MESH:D005234 Fatty Liver Valproic Acid 24.5114986274 19224547
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.9311858732
MESH:D005315 Fetal Diseases Valproic Acid 4.3416575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 3.6218558336 8888407
MESH:D005334 Fever endotoxin, Escherichia coli 8.2016997862
MESH:D005334 Fever Lipopolysaccharides 8.209205823 11852909
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 4.0519069698
MESH:D005355 Fibrosis Carbon Tetrachloride 22.2118705752
MESH:D005355 Fibrosis Curcumin 22.2118705752
MESH:D005355 Fibrosis Quercetin 22.2119474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 22.2120067830
MESH:D005355 Fibrosis Tretinoin 22.2117994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.7516904648
MESH:D005756 Gastritis Acetaminophen 3.1316983495
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.1718462866
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.1416452187
MESH:D005909 Glioblastoma Aspirin 27.8712870263
MESH:D005909 Glioblastoma Curcumin 27.8717596214
MESH:D005909 Glioblastoma Doxorubicin 27.8717150277
MESH:D005909 Glioblastoma Okadaic Acid 27.8717312396
MESH:D005909 Glioblastoma Quercetin 27.8719804834
MESH:D005909 Glioblastoma Tretinoin 27.8717312396
MESH:D005909 Glioblastoma trichostatin A 27.8718801729
MESH:D005910 Glioma Quercetin 2.8217643826
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.0510696789
MESH:D006261 Headache Aspirin 4.4115240983
MESH:D006258 Head and Neck Neoplasms Cisplatin 15.4015464296 15102660
MESH:D006258 Head and Neck Neoplasms Curcumin 15.4018829502 18462866
MESH:D006258 Head and Neck Neoplasms Doxorubicin 15.4015692506
MESH:D006258 Head and Neck Neoplasms Tretinoin 15.4016096774
MESH:D034381 Hearing Loss Cisplatin 3.8419898482
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.6116084493
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 3.9715464296
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 9.3511294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 9.3514991402 9664655
MESH:D006330 Heart Defects, Congenital Vitamin E 9.3516080930
MESH:D006331 Heart Diseases Doxorubicin 10.7116330681 17888722 18674790 16707910 16244371 12587719 16144979 14766674 17875725 18006777 16879835 16244372 16495754
MESH:D006331 Heart Diseases pifithrin 10.7114766674
MESH:D006331 Heart Diseases Raloxifene 10.7111110106
MESH:D006333 Heart Failure Doxorubicin 9.7817481944
MESH:D006333 Heart Failure pirinixic acid 9.7820558911
MESH:D006333 Heart Failure Selenium 9.7817162251
MESH:D006394 Hemangiosarcoma Doxorubicin 3.4215692506
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 3.9116366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.8511000095
MESH:D006505 Hepatitis Carbon Tetrachloride 8.0119900420 19110552
MESH:D006505 Hepatitis Drugs, Chinese Herbal 8.0118339527
MESH:D006529 Hepatomegaly pirinixic acid 6.5319176532 19772884 16221962 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 6.5312621046 16120746 15340226
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.5117701891
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.4916863852 16490937
MESH:D006558 Herpes Genitalis Estradiol 4.4815709030
MESH:D006561 Herpes Simplex resveratrol 3.6516876885
MESH:D006628 Hirsutism Androgens 5.5316914592 17019078
MESH:D006689 Hodgkin Disease Cisplatin 9.7316200630 16170182
MESH:D006689 Hodgkin Disease Doxorubicin 9.7317606976 15147373 18501091
MESH:D006689 Hodgkin Disease sodium arsenite 9.7312676792
MESH:D019584 Hot Flashes Estradiol 8.2317088409
MESH:D019584 Hot Flashes Vitamin E 8.2314716179
MESH:D006849 Hydrocephalus Valproic Acid 4.3317688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.508697196 16354765 18606429 16959395 15340226
MESH:D012001 Hyperacusis Aspirin 5.2115240983
MESH:D006930 Hyperalgesia Acetaminophen 10.7516870215
MESH:D006930 Hyperalgesia Prazosin 10.7512727271
MESH:D006930 Hyperalgesia Tretinoin 10.7516870215
MESH:D017588 Hyperandrogenism Androgens 5.1917019078
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.9916899240
MESH:D006937 Hypercholesterolemia Curcumin 7.7918704882
MESH:D006937 Hypercholesterolemia resveratrol 7.7917188708
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.0416778211
MESH:D006943 Hyperglycemia pirinixic acid 7.6920558911
MESH:D006943 Hyperglycemia Quercetin 7.6918262572 11834736
MESH:D006949 Hyperlipidemias resveratrol 3.5416873680
MESH:D006973 Hypertension Phenylephrine 10.488949925 12717712
MESH:D006973 Hypertension Quercetin 10.4818356687
MESH:D006973 Hypertension Raloxifene 10.4815787275 17577099
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 10.4818850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.5615338365
MESH:D006984 Hypertrophy Phenylephrine 4.0718502941 12791704
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 3.8317488730
MESH:D020244 Infarction, Middle Cerebral Artery pifithrin 10.2119475672
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 10.2117600658
MESH:D007248 Infertility, Male sodium arsenite 2.6315346721 12646999
MESH:D007249 Inflammation Curcumin 12.6616956363 18403477 17151092
MESH:D007249 Inflammation Lipopolysaccharides 12.6617237260 12878042 17255318 9205823 17963957
MESH:D007249 Inflammation resveratrol 12.6616366677
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 12.6612200463 12878042
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 12.667562506 8273558 11698051 15177302 7812673
MESH:D015212 Inflammatory Bowel Diseases Curcumin 2.9718200517 18596194
MESH:D007251 Influenza, Human Quercetin 22.1416624496
MESH:D007251 Influenza, Human resveratrol 22.1416624496
MESH:D007251 Influenza, Human Selenium 22.1416624496
MESH:D007251 Influenza, Human Vitamin E 22.1416624496
MESH:D007333 Insulin Resistance Estradiol 5.9816627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 5.9816306350
MESH:D007410 Intestinal Diseases Tretinoin 3.2517994277
MESH:D007414 Intestinal Neoplasms Curcumin 3.7510783313
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.1317255318
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 8.3316580747
MESH:D007569 Jaw Abnormalities Tretinoin 8.3315992940 17551590
MESH:D007627 Keloid Quercetin 4.4317086741
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.5915464296
MESH:D007674 Kidney Diseases Acetaminophen 28.1612587719 15629191
MESH:D007674 Kidney Diseases Acrolein 28.1612488133
MESH:D007674 Kidney Diseases Cisplatin 28.1619839026 15190930 18289764 12649298 12231392
MESH:D007674 Kidney Diseases Doxorubicin 28.1615369732 16775033 15699352
MESH:D007674 Kidney Diseases Estradiol 28.1615618244
MESH:D007674 Kidney Diseases Quercetin 28.1616962696
MESH:D007674 Kidney Diseases sodium arsenite 28.1620008137
MESH:D007674 Kidney Diseases Vitamin E 28.1612488133
MESH:D007676 Kidney Failure, Chronic Doxorubicin 8.3816707910
MESH:D007676 Kidney Failure, Chronic Selenium 8.3816518626
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 5.9116705839
MESH:D007680 Kidney Neoplasms Estradiol 5.9115610895
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 4.2511231351
MESH:D007889 Leiomyoma Curcumin 9.5018555241
MESH:D007889 Leiomyoma Raloxifene 9.5016973256
MESH:D007938 Leukemia arsenic trioxide 12.5715070760
MESH:D007938 Leukemia Curcumin 12.5718462866
MESH:D007938 Leukemia Quercetin 12.5717468513
MESH:D007938 Leukemia Tretinoin 12.5717143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.6116085563
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Drugs, Chinese Herbal 3.6815802533
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 8.1612560223 17077332
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 8.1616106398
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 9.9416972261
MESH:D007948 Leukemia, Monocytic, Acute PD 98059 9.9416972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.0214633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 7.8719077051
MESH:D007951 Leukemia, Myeloid Tretinoin 7.8716482212 19285840 16932348
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 7.7116467208 17050201 19850784 20471514 16968895
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 7.7117596541 16294345 19850784
MESH:D015470 Leukemia, Myeloid, Acute trichostatin A 7.7118206229
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 7.7117596541 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 10.6616823087 12712474 16112521 15336539 16966277 9834237 19035177 12018890 19075265 17712046 19642359 15748426 19225113 16331271 17107899 16330433 17649720 12679006 11468182 17217047 16891316 17869043 15213294 15622746 11161223
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 10.6616087638
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 10.6619225113 17361223 16935935 16891316 16331271 9834237 17301526 19035177 19029980 17712046 15748426 16788101 16766008 19075265 16140955 17294898 17339181 17506722 17368321 17649720 17217047 16823087 19642359 12679006 17107899
MESH:D015458 Leukemia, T-Cell arsenic trioxide 10.0116882451
MESH:D015458 Leukemia, T-Cell Curcumin 10.0116106398
MESH:D007970 Leukopenia Lipopolysaccharides 4.1615821434
MESH:D017880 Limb Deformities, Congenital Tretinoin 2.919224671
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 5.9916221502 17157831 11408273 11903743 16943688 21278145 16239168 17174718 17334410
MESH:D008103 Liver Cirrhosis Drugs, Chinese Herbal 5.9917163593
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 21.2815893842 17869086 15362042 18472332 16027843 17698563 16192424 16136751 18418968 17557913 15996030 12632514 18156304 12898905 12958196 14748882 17708605 18006644 18395095 18054572 15959796 12546737 18205269 15730626 18376398 18472094 18279442 15370692 12632512 14512876 17976157 14620537 18339082 15818738 12741479 15673190 17714472 18277467 12445421 12389079 16097048 15931870 18429990 12649538 16033810 12445418 17721639 18210741 12609069 17761835 14716833 16248980 17525996 18395914 18263696 16638106 16011737 15925388 18187930 17922224 17631135 15338365 17766677 18412020 15052691 17481882 12586293 17805973 17900296 17565644 17640975 20821823 13678700 12666154 12667390 16015684 18251166 14724832 15123356 18317297 18420326 15057751 15876570 18481824 10355542 16116963 18166357 11481614 17823541 18705752 14716496 17944888 15650968
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 21.2817355460 18705752 18006644
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 21.2816439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Drugs, Chinese Herbal 21.2815383259 17881167 12632512 15818738 18567088 17666798 15754396 18237412 17629604 16610055 17348192 15744066 15864749 18606216 18371158 17036385 15339415 15849816 15641146 15763062
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 21.2814659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 21.2812878042
MESH:D008106 Liver Cirrhosis, Experimental oxymatrine 21.2818395914 15633229
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 21.2815474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 21.2812741479
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 21.2812878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 21.2818397230 16248980
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 21.2816169303
MESH:D008107 Liver Diseases Acetaminophen 8.0119784758 16610002 19014921 12587719 12969438 11587558 19460945 16611625
MESH:D008107 Liver Diseases Carbon Tetrachloride 8.0117285989 15720792 16964402 15830285 16246199
MESH:D008107 Liver Diseases Curcumin 8.0116956363
MESH:D008107 Liver Diseases Drugs, Chinese Herbal 8.0117207593
MESH:D017093 Liver Failure Carbon Tetrachloride 3.6415123358
MESH:D017114 Liver Failure, Acute Acetaminophen 7.8517185352 16871587
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 7.8516899240 14706259
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 25.457678174
MESH:D008113 Liver Neoplasms arsenic trioxide 25.4514682389
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 25.4519294768
MESH:D008113 Liver Neoplasms Drugs, Chinese Herbal 25.4518339527
MESH:D008113 Liver Neoplasms pirinixic acid 25.4520007298 15890375 16377806
MESH:D008113 Liver Neoplasms Quercetin 25.4518980244
MESH:D008113 Liver Neoplasms resveratrol 25.4519321006 19812893 20405173 19073162
MESH:D008113 Liver Neoplasms sodium arsenite 25.4516712894 15276417
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 25.4516984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 18.802876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 18.8020377131
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 18.8012014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 18.8017085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Quercetin 18.8019519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 18.8012151625
MESH:D008133 Long QT Syndrome arsenic trioxide 2.9415213294
MESH:D008171 Lung Diseases Acrolein 10.3111504702
MESH:D008171 Lung Diseases sodium arsenite 10.3119095001
MESH:D008171 Lung Diseases Vitamin E 10.3116863852
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 3.7117228818
MESH:D055370 Lung Injury Lipopolysaccharides 3.4921114838
MESH:D008175 Lung Neoplasms arsenic trioxide 15.9411798837 19825857
MESH:D008175 Lung Neoplasms Cisplatin 15.9411798837 6189445 17225452
MESH:D008175 Lung Neoplasms Curcumin 15.9419359593 18462866 16243823
MESH:D008175 Lung Neoplasms Doxorubicin 15.946189445 17418594
MESH:D008175 Lung Neoplasms Drugs, Chinese Herbal 15.9418339527
MESH:D008175 Lung Neoplasms Quercetin 15.9416280456
MESH:D008175 Lung Neoplasms sodium arsenite 15.9417077188 19931552 15276417 17306315 16712894
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 15.9411884234 19555203
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 15.9411807781
MESH:D008175 Lung Neoplasms Vitamin E 15.9411062179
MESH:D008223 Lymphoma Curcumin 6.4818462866
MESH:D008223 Lymphoma Doxorubicin 6.4816098063
MESH:D016393 Lymphoma, B-Cell resveratrol 3.8017088997
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 7.4117654614
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 7.4114749477
MESH:D016399 Lymphoma, T-Cell Curcumin 9.8216173963
MESH:D016399 Lymphoma, T-Cell Doxorubicin 9.8215621674
MESH:D016410 Lymphoma, T-Cell, Cutaneous vorinostat 5.1620479100
MESH:D015674 Mammary Neoplasms, Animal resveratrol 3.7115688416
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 18.9115458769
MESH:D008325 Mammary Neoplasms, Experimental Drugs, Chinese Herbal 18.9114758024
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 18.9111807958 17203775 16891317 11408345
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 18.9111606380 8985016
MESH:D008325 Mammary Neoplasms, Experimental Selenium 18.9115318939
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 18.918985016
MESH:D020149 Manganese Poisoning Estradiol 3.9319453300
MESH:D008527 Medulloblastoma Tretinoin 2.5517453147
MESH:D008545 Melanoma Cisplatin 13.4712374674 18176117 11135225 15577323 12883367 16248763 18332650 17023156 12393984 16432458 17761969 18505091 16809738
MESH:D008545 Melanoma Curcumin 13.4718462866 17885582
MESH:D008545 Melanoma Doxorubicin 13.4716827129
MESH:D008545 Melanoma resveratrol 13.4717992120
MESH:D008545 Melanoma sodium arsenite 13.4716487513 19082730
MESH:D008545 Melanoma Tretinoin 13.4716752155
MESH:D008545 Melanoma trichostatin A 13.4716505122
MESH:D018328 Melanoma, Amelanotic Cisplatin 4.2415990972
MESH:D008546 Melanoma, Experimental Acetaminophen 9.2419513568
MESH:D008546 Melanoma, Experimental Acrolein 9.2410803710
MESH:D008569 Memory Disorders Curcumin 3.6517263510
MESH:D008591 Meningomyelocele Tretinoin 3.9016940565
MESH:D008654 Mesothelioma Cisplatin 8.8417638057
MESH:D008654 Mesothelioma Doxorubicin 8.8417638057
MESH:D008654 Mesothelioma Selenium 8.8415107826
MESH:D008659 Metabolic Diseases resveratrol 3.8917112576
MESH:D008881 Migraine Disorders Aspirin 6.5615240983
MESH:D008881 Migraine Disorders Valproic Acid 6.5618803445 18765137
MESH:D020326 Migraine without Aura Cyclic AMP 4.6511304026
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.0115792986
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.0115863610
MESH:D052016 Mucositis Doxorubicin 10.6317415656
MESH:D052016 Mucositis irinotecan 10.6317159606
MESH:D009101 Multiple Myeloma arsenic trioxide 18.5214977855 19417148 15949261 11468182 19549372
MESH:D009101 Multiple Myeloma Curcumin 18.5219372569
MESH:D009101 Multiple Myeloma Raloxifene 18.5216497877
MESH:D009101 Multiple Myeloma resveratrol 18.5217164350 17935668 16267019 14749477 17049120 16490592
MESH:D009101 Multiple Myeloma trichostatin A 18.5218172295
MESH:D009134 Muscular Atrophy, Spinal Curcumin 10.6317962980
MESH:D009134 Muscular Atrophy, Spinal resveratrol 10.6317962980
MESH:D009135 Muscular Diseases Bezafibrate 8.9916239165
MESH:D009135 Muscular Diseases pirinixic acid 8.9916239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 3.548888407
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.1218349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 10.4016882451 16105982
MESH:D009190 Myelodysplastic Syndromes Tretinoin 10.4017596541
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 10.4017596541
MESH:D009203 Myocardial Infarction Aspirin 15.2112692751
MESH:D009203 Myocardial Infarction Doxorubicin 15.2119429709 15857846
MESH:D009203 Myocardial Infarction pirinixic acid 15.2119151258
MESH:D009203 Myocardial Infarction Quercetin 15.2119595682
MESH:D009203 Myocardial Infarction resveratrol 15.2116456233 17125593 17015251 16525036 16317513 17188708
MESH:D017202 Myocardial Ischemia resveratrol 7.5817015251 17125593
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 7.5812213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 11.7716810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 11.7716411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 11.7719207477
MESH:D009205 Myocarditis resveratrol 4.2217322642
MESH:D009232 Myxoma Raloxifene 5.0116343187
MESH:D009325 Nausea Aspirin 10.4015240983
MESH:D009325 Nausea vorinostat 10.4020479100
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.3318551238 7678174
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 8.6316624393
MESH:D009361 Neoplasm Invasiveness Curcumin 8.6318495463
MESH:D009362 Neoplasm Metastasis Doxorubicin 5.2918259882
MESH:D009362 Neoplasm Metastasis irinotecan 5.2918259882
MESH:D009369 Neoplasms Acrolein 16.0117329238
MESH:D009369 Neoplasms Cisplatin 16.0116773208
MESH:D009369 Neoplasms pirinixic acid 16.0117405874
MESH:D009369 Neoplasms Quercetin 16.0115185748
MESH:D009369 Neoplasms sodium arsenite 16.0111559025
MESH:D009369 Neoplasms Tretinoin 16.0116946489 16594593
MESH:D009374 Neoplasms, Experimental resveratrol 7.498985016
MESH:D009374 Neoplasms, Experimental sodium arsenite 7.4920056578
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 3.9912497104
MESH:D009389 Neovascularization, Pathologic Estradiol 3.2017289903
MESH:D009393 Nephritis Acrolein 5.7412653641
MESH:D009395 Nephritis, Interstitial Cisplatin 3.9515464296
MESH:D009401 Nephrosis Doxorubicin 4.2416899518 16636307
MESH:D009404 Nephrotic Syndrome Doxorubicin 3.5515640375 16889571
MESH:D009421 Nervous System Malformations Estradiol 13.3816427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 13.3814600291
MESH:D009421 Nervous System Malformations Tretinoin 13.389125849
MESH:D009423 Nervous System Neoplasms Curcumin 5.0818462866
MESH:D009436 Neural Tube Defects arsenic trioxide 14.3310525206
MESH:D009436 Neural Tube Defects sodium arsenite 14.3312854658
MESH:D009436 Neural Tube Defects Tretinoin 14.339142499
MESH:D009436 Neural Tube Defects Valproic Acid 14.3316359493 8888407
MESH:D009447 Neuroblastoma Cisplatin 9.788761367
MESH:D009447 Neuroblastoma Doxorubicin 9.7815555623
MESH:D009447 Neuroblastoma irinotecan 9.788761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 11.6618514411
MESH:D019636 Neurodegenerative Diseases Acrolein 11.6611342003
MESH:D019636 Neurodegenerative Diseases resveratrol 11.6617652729
MESH:D017599 Neuroectodermal Tumors Cisplatin 9.688761367
MESH:D017599 Neuroectodermal Tumors irinotecan 9.688761367
MESH:D020078 Neurogenic Inflammation Quercetin 9.0517929310
MESH:D020078 Neurogenic Inflammation resveratrol 9.0517929310
MESH:D009765 Obesity Curcumin 4.0619297423
MESH:D009765 Obesity pirinixic acid 4.0620558911
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 2.9716049721
MESH:D010003 Osteoarthritis Aspirin 3.727009135
MESH:D010024 Osteoporosis Curcumin 6.2518719352
MESH:D010024 Osteoporosis Raloxifene 6.2517882678 19059307 15775268
MESH:D015663 Osteoporosis, Postmenopausal Drugs, Chinese Herbal 20.0016548355
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 20.0019495926
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 20.0017893378 17823083 15579764 15758505
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 20.0017513867
MESH:D012516 Osteosarcoma Doxorubicin 3.6815930896
MESH:D010051 Ovarian Neoplasms arsenic trioxide 27.4819769630 12452020 16624393
MESH:D010051 Ovarian Neoplasms Cisplatin 27.4819769630 6897625 17225452 15464296
MESH:D010051 Ovarian Neoplasms Curcumin 27.4818462866 19020741
MESH:D010051 Ovarian Neoplasms Estradiol 27.4819401270
MESH:D010051 Ovarian Neoplasms Mifepristone 27.4816525653
MESH:D010051 Ovarian Neoplasms Quercetin 27.4819005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 27.4815276417 17306315
MESH:D010051 Ovarian Neoplasms Tretinoin 27.4816936753
MESH:D010051 Ovarian Neoplasms trichostatin A 27.4819331143
MESH:D010146 Pain Acetaminophen 8.8116870215
MESH:D010146 Pain Aspirin 8.816363464 6995502
MESH:D010146 Pain Tretinoin 8.8116870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 21.4215580305
MESH:D010190 Pancreatic Neoplasms Cisplatin 21.4219003803
MESH:D010190 Pancreatic Neoplasms Curcumin 21.4217440100 19196508 19401701
MESH:D010190 Pancreatic Neoplasms Quercetin 21.4216965848
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 21.4215976015
MESH:D010190 Pancreatic Neoplasms Tretinoin 21.4215976015
MESH:D010190 Pancreatic Neoplasms trichostatin A 21.4219294695
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 3.7718404319 8330346 18922899 12065085
MESH:D010235 Paraganglioma arsenic trioxide 3.6619927285
MESH:D010300 Parkinson Disease Acrolein 3.3717690948
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.7012520081
MESH:D010438 Peptic Ulcer Hemorrhage Aspirin 5.0011156591
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 3.8015464296
MESH:D020795 Photophobia Aspirin 5.2115240983
MESH:D010787 Photosensitivity Disorders 4-hydroxy-2-nonenal 11.6411550810
MESH:D010787 Photosensitivity Disorders Acrolein 11.6411550810
MESH:D003557 Phyllodes Tumor Doxorubicin 4.6117983394
MESH:D010954 Plasmacytoma Selenium 4.3415087411
MESH:D010997 Pleural Neoplasms Cisplatin 12.1117638057
MESH:D010997 Pleural Neoplasms Doxorubicin 12.1117638057
MESH:D011014 Pneumonia Lipopolysaccharides 4.0211605937 12224865
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.0518163543
MESH:D011230 Precancerous Conditions Quercetin 3.5319056647
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 13.1716679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 13.1711399792 11896295 11118676 11222880
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 13.1720603192
MESH:D055728 Primary Myelofibrosis trichostatin A 4.7317616702
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.2415572423
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.4020887781
MESH:D011471 Prostatic Neoplasms marker/mechanism 15378487
MESH:D011471 Prostatic Neoplasms Androgens 6.2616998812 15389811 17909013
MESH:D011471 Prostatic Neoplasms arsenic trioxide 6.2619131511
MESH:D011471 Prostatic Neoplasms bicalutamide 6.2617914592 18487222 19011039 19240160 15638997
MESH:D011471 Prostatic Neoplasms Calcitriol 6.2618247401 15754350 16644109 16289102 12479363
MESH:D011471 Prostatic Neoplasms Curcumin 6.2611398177 18769126 15129424 18156803 10851300 12497104 18226269
MESH:D011471 Prostatic Neoplasms Doxorubicin 6.2615897917 15749863 16868541 18437689 16888761 16729912
MESH:D011471 Prostatic Neoplasms Estradiol 6.2616740699
MESH:D011471 Prostatic Neoplasms Quercetin 6.2617292933 14715546
MESH:D011471 Prostatic Neoplasms Raloxifene 6.2616536755 15731164 16220300
MESH:D011471 Prostatic Neoplasms resveratrol 6.2617636462 17804756 17718901 17675339 15767336 16731767
MESH:D011471 Prostatic Neoplasms sodium arsenite 6.2616039940
MESH:D011471 Prostatic Neoplasms trichostatin A 6.2619789329 18798265
MESH:D011471 Prostatic Neoplasms Vitamin E 6.2615084515
MESH:D011471 Prostatic Neoplasms vorinostat 6.2617218635
MESH:D011507 Proteinuria Tretinoin 3.1116636307
MESH:D019310 Pseudolymphoma Valproic Acid 3.9912752131 11422049
MESH:D011625 Pterygium Tretinoin 4.2516723453
MESH:D011656 Pulmonary Emphysema Curcumin 4.0619168576
MESH:D011658 Pulmonary Fibrosis Drugs, Chinese Herbal 3.4916987627
MESH:D011693 Purpura Raloxifene 5.0115770314
MESH:D012003 Rectal Fistula Drugs, Chinese Herbal 5.4215043669
MESH:D051437 Renal Insufficiency Acrolein 14.2712732208
MESH:D051437 Renal Insufficiency Cisplatin 14.2715464296
MESH:D051437 Renal Insufficiency Doxorubicin 14.2717922066
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.0316325855
MESH:D015427 Reperfusion Injury pirinixic acid 5.6119058328
MESH:D015427 Reperfusion Injury resveratrol 5.6116314181 16317513 15827377 17520802 17058453
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 3.5318379247 10666014
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.3610835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.3318990726
MESH:D012208 Rhabdomyosarcoma Tretinoin 9.2116116481 16283617
MESH:D012208 Rhabdomyosarcoma Valproic Acid 9.2119155313
MESH:D012220 Rhinitis Aspirin 3.9112372130
MESH:D012221 Rhinitis, Allergic, Perennial Drugs, Chinese Herbal 4.7315015336
MESH:D012415 Rubinstein-Taybi Syndrome marker/mechanism
MESH:D012509 Sarcoma Curcumin 8.0118462866
MESH:D012509 Sarcoma Doxorubicin 8.0116767912 18313854 17203757 17710206 15675481 15625365
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 14.3416646077
MESH:D012512 Sarcoma, Ewing's Cisplatin 14.3414601052
MESH:D012512 Sarcoma, Ewing's Doxorubicin 14.3414601052 16326096
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.2517846226
MESH:D012554 Schistosomiasis japonica Quercetin 5.0016862918
MESH:D012559 Schizophrenia Valproic Acid 1.9919110320 15737665
MESH:D012640 Seizures 2,6-dinitrotoluene 4.7118551238
MESH:D012640 Seizures Valproic Acid 4.7111738929 14763951 11044598 3137016 1511512 17978042 15475178 16876388
MESH:D018805 Sepsis Curcumin 3.6318389075
MESH:D012772 Shock, Septic endotoxin, Escherichia coli 5.1018063050
MESH:D012852 Sinusitis Phenylephrine 4.177327846
MESH:D012851 Sinus Thrombosis, Intracranial Aspirin 4.7412269725
MESH:D012871 Skin Diseases Vitamin E 2.2818709164
MESH:D012878 Skin Neoplasms Doxorubicin 22.9215692506
MESH:D012878 Skin Neoplasms Okadaic Acid 22.9212628509
MESH:D012878 Skin Neoplasms resveratrol 22.9215837718 8985016
MESH:D012878 Skin Neoplasms sodium arsenite 22.9218572023 19524636
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 22.9216192470
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 22.928330346 11807781 18404319 8985016 12065085
MESH:D012878 Skin Neoplasms Tretinoin 22.9216467112
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 4.7915464296
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.0416767912 15625365 17203757
MESH:D016135 Spinal Dysraphism sodium arsenite 8.1512854658
MESH:D016135 Spinal Dysraphism Valproic Acid 8.1519490988
MESH:D013226 Status Epilepticus Valproic Acid 3.9912833885
MESH:D013274 Stomach Neoplasms arsenic trioxide 5.6517007042
MESH:D013274 Stomach Neoplasms Cisplatin 5.6518396642 17522103 15958060
MESH:D013274 Stomach Neoplasms Drugs, Chinese Herbal 5.6518339527
MESH:D013274 Stomach Neoplasms irinotecan 5.6515723263
MESH:D013274 Stomach Neoplasms Tretinoin 5.6517261132
MESH:D013276 Stomach Ulcer Curcumin 3.0419188055 16631530
MESH:D020521 Stroke Acrolein 17.0616269634
MESH:D020521 Stroke Aspirin 17.0616403987
MESH:D020521 Stroke Raloxifene 17.0616837676
MESH:D020521 Stroke Vitamin E 17.0616517955
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.0116321402
MESH:D013345 Subarachnoid Hemorrhage Drugs, Chinese Herbal 11.8517634840
MESH:D013345 Subarachnoid Hemorrhage pifithrin 11.8518364113
MESH:D024801 Tauopathies Camptothecin 5.0916930453
MESH:D013736 Testicular Neoplasms Cisplatin 4.1317225452 15464296
MESH:D013921 Thrombocytopenia Lipopolysaccharides 8.5715821434
MESH:D013921 Thrombocytopenia vorinostat 8.5720479100
MESH:D013927 Thrombosis Aspirin 4.0617672075
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.3512697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 9.6319014326
MESH:D013964 Thyroid Neoplasms Doxorubicin 9.6317909728 16010429
MESH:D013964 Thyroid Neoplasms Tretinoin 9.6317045167 16026305
MESH:D013978 Tibial Fractures Estradiol 11.8919048282
MESH:D013978 Tibial Fractures Raloxifene 11.8919048282
MESH:D014062 Tongue Neoplasms resveratrol 8.3516227395
MESH:D014062 Tongue Neoplasms Tretinoin 8.3516051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.4315213294
MESH:D014178 Translocation, Genetic Valproic Acid 4.6817262798
MESH:D014376 Tuberculosis Tretinoin 2.8816040207
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 3.983119515
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 24.2816049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 24.2820435036 12845720 11780464 12973940
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 24.2815464296 12973940 17225452
MESH:D001749 Urinary Bladder Neoplasms Curcumin 24.2818593936
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 24.2817653716
MESH:D001749 Urinary Bladder Neoplasms Quercetin 24.2816720314
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 24.2817572228
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 24.2811723127 17306315 16712894 16452187
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.128888407
MESH:D014565 Urogenital Neoplasms Curcumin 4.7318462866
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 3.7810091137
MESH:D014581 Urticaria Acetaminophen 7.2610982225
MESH:D014581 Urticaria Aspirin 7.2620485159 10982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 18.8116803524
MESH:D002583 Uterine Cervical Neoplasms resveratrol 18.8117473185
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 18.8111813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 18.8116129372
MESH:D014594 Uterine Neoplasms resveratrol 3.6317044934
MESH:D014604 Uveal Neoplasms Tretinoin 4.0616752155
MESH:D014625 Vaginal Neoplasms Cisplatin 4.0915577323
MESH:D014652 Vascular Diseases sodium arsenite 3.8917056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.0512125929
MESH:D020301 Vasospasm, Intracranial pifithrin 5.0818364113
MESH:D054556 Venous Thromboembolism Raloxifene 4.6616837676
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 8.6017678736 17638931 17334414 16364871
MESH:D018487 Ventricular Dysfunction, Left resveratrol 8.6017488730
MESH:D014820 Vitiligo Tretinoin 3.5516761959
MESH:D014839 Vomiting Cisplatin 4.1711897121
MESH:D014846 Vulvar Neoplasms Raloxifene 5.0116343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.7015886252
MESH:D009396 Wilms Tumor Tretinoin 3.5116287080
MESH:D014947 Wounds and Injuries Drugs, Chinese Herbal 4.1016313111
Pathway ID Pathway Name
KEGG:04520 Adherens junction
KEGG:04110 Cell cycle
REACT:15380 Diabetes pathways
REACT:71 Gene Expression
KEGG:05016 Huntington's disease
KEGG:04630 Jak-STAT signaling pathway
KEGG:04720 Long-term potentiation
KEGG:04916 Melanogenesis
REACT:22258 Metabolism of lipids and lipoproteins
KEGG:04330 Notch signaling pathway
KEGG:05200 Pathways in cancer
KEGG:05215 Prostate cancer
KEGG:05211 Renal cell carcinoma
REACT:6900 Signaling in Immune system
KEGG:04350 TGF-beta signaling pathway
KEGG:05152 Tuberculosis
KEGG:04310 Wnt signaling pathway
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA26866
    • Releated gene ID Related gene Name
    PA27807EP300
    Releated disease ID Related disease Name
    PA447066Spinocerebellar Ataxias
    Releated drug ID Related drug Name
    PA151958596curcumin
    PA449167cyclosporine
    PA10804imatinib
    PA449247dexamethasone
    PA451578tacrolimus
    PA164743471adenosine triphosphate
    PA164768822chlorotrianisene
    PA164754789conjugated estrogens
    PA164745534dienestrol
    PA449307diethylstilbestrol
    PA449503estradiol
    PA449509estrogens
    PA449512estrone
    PA449527ethinyl estradiol
    PA151929741trichostatin A
    PA452347glucocorticoids
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB08655 - 9-ACETYL-2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-ONE
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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