AutismKB 2.0

Annotation Detail for CREM


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Basic Information Top
Gene Symbol:CREM ( ICER,MGC111110,MGC17881,MGC41893,hCREM-2 )
Gene Full Name: cAMP responsive element modulator
Band: 10p11.21
Quick LinksEntrez ID:1390; OMIM: 123812; Uniprot ID:CREM_HUMAN; ENSEMBL ID: ENSG00000095794; HGNC ID: 2352
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
P00026Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
P00006Apoptosis signaling pathway
P00055Transcription regulation by bZIP transcription factor
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Related Diseases/Disorders Top
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Desease IDDesease Name
1800Lupus vulgaris
1836Panic disorder
1823Infertility, Male
2146Lupus erythematosus
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of CREM mRNAaffects expression 21346803
C518576 2-methylbutyric acid 4-((1,3)dioxan-5-ylmethoxyimino)-8-(2-(4-hydroxy-6-oxo-tetrahydropyran-2-yl)ethyl -7-methyl-6-oxo-1,2,3,4,6,7,8,8a-octahydronaphthyl)heptanoate 2-methylbutyric acid 4-((1,3)dioxan-5-ylmethoxyimino)-8-(2-(4-hydroxy-6-oxo-tetrahydropyran-2-yl)ethyl -7-methyl-6-oxo-1,2,3,4,6,7,8,8a-octahydronaphthyl)heptanoate results in decreased expression of CREM mRNAdecreases expression 17327690
C023035 3,4,5,3',4'-pentachlorobiphenyl 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CREM protein alternative formincreases expression 16081525
D000082 Acetaminophen Acetaminophen affects the expression of CREM mRNAaffects expression 17562736
D000638 Amiodarone Amiodarone affects the expression of CREM mRNAaffects expression 19483382
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CREM mRNAaffects expression 16483693
D003913 Dextroamphetamine Dextroamphetamine results in increased expression of CREM mRNAincreases expression 12558987
19194377
D000661 Amphetamine CREM protein results in increased susceptibility to Amphetamineincreases response to substance 16899718
D000661 Amphetamine Amphetamine results in increased expression of CREM mRNAincreases expression 16899718
D001151 Arsenic Arsenic results in decreased expression of CREM mRNAdecreases expression 19654921
C006632 arsenic trioxide arsenic trioxide results in increased expression of CREM mRNAincreases expression 20458559
D001553 Benzbromarone Benzbromarone affects the expression of CREM mRNAaffects expression 19483382
D001554 Benzene Benzene results in increased expression of CREM mRNAincreases expression 15929907
D019324 beta-Naphthoflavone beta-Naphthoflavone results in increased expression of CREM mRNAincreases expression 19737606
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CREM mRNAaffects cotreatment|increases expression 18164116
C005961 bis(tri-n-butyltin)oxide bis(tri-n-butyltin)oxide results in increased expression of CREM mRNAincreases expression 17553608
D002994 Clofibrate Clofibrate affects the expression of CREM mRNAaffects expression 19483382
D003520 Cyclophosphamide Cyclophosphamide results in decreased expression of CREM mRNAdecreases expression 17624719
D003520 Cyclophosphamide Cyclophosphamide results in decreased expression of CREM proteindecreases expression 17624719
D003520 Cyclophosphamide Drugs, Chinese Herbal inhibits the reaction [Cyclophosphamide results in decreased expression of CREM mRNA]decreases expression|decreases reaction 17624719
D003520 Cyclophosphamide Drugs, Chinese Herbal inhibits the reaction [Cyclophosphamide results in decreased expression of CREM protein]decreases expression|decreases reaction 17624719
D016572 Cyclosporine Cyclosporine results in increased expression of CREM mRNAincreases expression 20106945
D004041 Dietary Fats Dietary Fats results in decreased expression of CREM mRNAdecreases expression 18042831
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CREM mRNAaffects cotreatment|increases expression 18164116
D004280 Dobutamine CREM protein affects the susceptibility to Dobutamineaffects response to substance 12475904
D004365 Drugs, Chinese Herbal Drugs, Chinese Herbal inhibits the reaction [Cyclophosphamide results in decreased expression of CREM mRNA]decreases expression|decreases reaction 17624719
D004365 Drugs, Chinese Herbal Drugs, Chinese Herbal inhibits the reaction [Cyclophosphamide results in decreased expression of CREM protein]decreases expression|decreases reaction 17624719
D004958 Estradiol Estradiol results in increased expression of CREM mRNAincreases expression 20106945
D000431 Ethanol Ethanol results in increased expression of CREM mRNAincreases expression 15353170
16098508
D005001 Ethionine Ethionine affects the expression of CREM mRNAaffects expression 19483382
D005047 Etoposide CREM protein affects the susceptibility to Etoposideaffects response to substance 16217747
D005576 Forskolin Forskolin results in increased expression of CREM mRNAincreases expression 12791704
D007545 Isoproterenol CREM protein inhibits the reaction [Isoproterenol results in increased activity of CREB1 protein]decreases reaction|increases activity 12791704
D007545 Isoproterenol CREM protein inhibits the reaction [Isoproterenol results in increased expression of FOS mRNA]decreases reaction|increases expression 12791704
D007545 Isoproterenol CREM protein inhibits the reaction [Isoproterenol results in increased expression of NPPA protein]decreases reaction|increases expression 12791704
D007545 Isoproterenol Isoproterenol affects the localization of CREM proteinaffects localization 12791704
D007545 Isoproterenol Isoproterenol results in increased expression of CREM mRNAincreases expression 12791704
D007545 Isoproterenol Isoproterenol results in increased expression of CREM proteinincreases expression 12791704
D008770 Methylnitrosourea Methylnitrosourea results in increased expression of CREM mRNAincreases expression 17412507
C029938 nickel sulfate nickel sulfate results in increased expression of CREM mRNAincreases expression 16780908
D009853 Omeprazole Omeprazole affects the expression of CREM mRNAaffects expression 19483382
C041786 palm oil palm oil results in decreased expression of CREM mRNAdecreases expression 18042831
D010656 Phenylephrine Phenylephrine results in increased expression of CREM mRNAincreases expression 12791704
18158353
C006253 pirinixic acid pirinixic acid affects the expression of CREM mRNAaffects expression 19483382
C045950 propiconazole propiconazole results in decreased expression of CREM mRNAdecreases expression 19423681
D011441 Propylthiouracil Propylthiouracil affects the expression of CREM mRNAaffects expression 19483382
C009250 sevoflurane sevoflurane affects the expression of CREM mRNAaffects expression 15967596
C017947 sodium arsenite sodium arsenite results in increased expression of and results in increased activity of CREM protein alternative formincreases activity|increases expression 14523996
C446685 systhane systhane results in decreased expression of CREM mRNAdecreases expression 19423681
D013853 Thioacetamide Thioacetamide affects the expression of CREM mRNAaffects expression 19483382
C032910 triadimefon triadimefon results in decreased expression of CREM mRNAdecreases expression 19423681
D014241 Trichloroethylene Trichloroethylene results in decreased expression of CREM mRNAdecreases expression 17905399
C081489 valsartan valsartan results in decreased expression of CREM mRNAdecreases expression 19027736
C025643 vinclozolin vinclozolin affects the expression of CREM mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Ethanol 3.4718926900 17676605
MESH:D000038 Abscess Drugs, Chinese Herbal 5.8515043669
MESH:D000138 Acidosis Ammonium Chloride 8.9618287403
MESH:D000138 Acidosis Ethanol 8.9611192467
MESH:D055371 Acute Lung Injury nickel sulfate 7.7611954676 16100012 19131640 12718980
MESH:D055371 Acute Lung Injury pirinixic acid 7.7618653653
MESH:D000230 Adenocarcinoma arsenic trioxide 6.4319825857 11798837
MESH:D000230 Adenocarcinoma Estradiol 6.4311473722
MESH:D000230 Adenocarcinoma Methylnitrosourea 6.4315688392 15113128
MESH:D000236 Adenoma beta-Naphthoflavone 5.9719389873
MESH:D000236 Adenoma Diethylnitrosamine 5.976695378 10737359
MESH:D018248 Adenoma, Liver Cell 3,4,5,3',4'-pentachlorobiphenyl 14.9016628245
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 14.9016434500 17620307 19052882 19061943 18056438 17162532
MESH:D018248 Adenoma, Liver Cell pirinixic acid 14.9016434500
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.2415276417
MESH:D018246 Adrenocortical Adenoma Arsenic 12.2517306315
MESH:D018246 Adrenocortical Adenoma sodium arsenite 12.2516712894 17306315
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.8615451040 15451039
MESH:D019969 Amphetamine-Related Disorders Amphetamine 5.6016916582 15010207 18475255 16459022
MESH:D000740 Anemia Drugs, Chinese Herbal 4.2717963324 15504547
MESH:D000741 Anemia, Aplastic Benzene 4.0217661222 11369114 14761424
MESH:D000787 Angina Pectoris Drugs, Chinese Herbal 4.9511477813
MESH:D000799 Angioedema Acetaminophen 3.3810982225
MESH:D000853 Anophthalmos Ethanol 4.3815513904
MESH:D000855 Anorexia Amphetamine 4.6216101753 16084549 12005258 12183048
MESH:D001004 Anus Diseases Drugs, Chinese Herbal 5.5015043669
MESH:D001008 Anxiety Disorders Ethanol 7.8211141031
MESH:D001008 Anxiety Disorders vinclozolin 7.8219015723
MESH:D001145 Arrhythmias, Cardiac Amiodarone 7.8418057881 20041841 18218290
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 7.8417460149
MESH:D020261 Arsenic Poisoning Arsenic 2.7316251483 12569548 16835338 18414634
MESH:D001161 Arteriosclerosis Cyclophosphamide 8.8515014928
MESH:D001161 Arteriosclerosis Dietary Fats 8.8515238619
MESH:D015210 Arthritis, Gouty Drugs, Chinese Herbal 5.3019655406
MESH:D050197 Atherosclerosis Arsenic 2.9812928151 19371607
MESH:D001281 Atrial Fibrillation Amiodarone 3.5618651412 19698954
MESH:D001321 Autistic Disorder Acetaminophen 1.4718445737
MESH:D001778 Blood Coagulation Disorders Amiodarone 50.2219483382
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 50.2216206674
MESH:D001778 Blood Coagulation Disorders Benzbromarone 50.2219483382
MESH:D001778 Blood Coagulation Disorders Clofibrate 50.2219483382
MESH:D001778 Blood Coagulation Disorders Ethionine 50.2219483382
MESH:D001778 Blood Coagulation Disorders Omeprazole 50.2219483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 50.2219483382
MESH:D001778 Blood Coagulation Disorders Propylthiouracil 50.2219483382
MESH:D001778 Blood Coagulation Disorders Thioacetamide 50.2219483382
MESH:D001855 Bone Marrow Diseases Benzene 4.7716183116
MESH:D019046 Bone Marrow Neoplasms Etoposide 4.7014601052
MESH:D001862 Bone Resorption Drugs, Chinese Herbal 4.429881647
MESH:D001919 Bradycardia Isoproterenol 9.456740701
MESH:D001919 Bradycardia Phenylephrine 9.4515306635
MESH:D001943 Breast Neoplasms Benzene 4.2811921183 17162533
MESH:D001943 Breast Neoplasms Cyclophosphamide 4.2815136595 11325840 15093573 18323546 17020986 17388661 18234424 12006526 16978400
MESH:D001943 Breast Neoplasms Dietary Fats 4.2820435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 4.2817474063
MESH:D001943 Breast Neoplasms Estradiol 4.2817289903 16675129 12948864 19861407 14630087 18497071 17261762 17018787
MESH:D001943 Breast Neoplasms Etoposide 4.2816322251
MESH:D001943 Breast Neoplasms Methylnitrosourea 4.2816253758 11306469 14633655
MESH:D001943 Breast Neoplasms Trichloroethylene 4.2815986119
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.9111589617
MESH:D002056 Burns Ethanol 4.2116374292
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.0116111702
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.3317687452 15504454
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 23.9716705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 23.973084413
MESH:D006528 Carcinoma, Hepatocellular Arsenic 23.9716507464 17306315
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 23.9715073043 16217749 15553829 14691202 11135700
MESH:D006528 Carcinoma, Hepatocellular Benzbromarone 23.971701930
MESH:D006528 Carcinoma, Hepatocellular Cyclophosphamide 23.9719701751
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 23.973084413 18665156 19701751 18971187 16502159 16779866 20727157 3581430 20007298 19394651 20524982 19335982 19539802 16681979 19171122 20084675 17761372 18691550 16569478 10737359 19822196 19519916 20214788 20432363 17978847 21159647 16328049 16807293 19208518 18785209 16288022 19418558 18393292 20935162 17173139 17428255 17138121 11831363 18506893 18978308 16935385 18056438 19052882 18494052 18210153 16830150 20512989 16540662 20101231 17162532 18788625 20514400 10672840 19383236 16878318 19919837 16698587 17055752 19107877
MESH:D006528 Carcinoma, Hepatocellular Estradiol 23.9716924424
MESH:D006528 Carcinoma, Hepatocellular Ethanol 23.9715289165 15763234 18788625
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 23.9717306315 15276417 16507464
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 23.9717997003
MESH:D018827 Carcinoma, Lewis Lung Cyclophosphamide 4.4416152834
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.4119014326
MESH:D002292 Carcinoma, Renal Cell Cyclophosphamide 3.3116201981
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.7212490120
MESH:D002294 Carcinoma, Squamous Cell Arsenic 4.3318922899 15504454 17687452
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 4.3318572023
MESH:D002295 Carcinoma, Transitional Cell Arsenic 3.6818640142
MESH:D006332 Cardiomegaly Ethanol 14.3219332462
MESH:D006332 Cardiomegaly Isoproterenol 14.3211179087 7544033
MESH:D006332 Cardiomegaly Phenylephrine 14.3211754973 11179087 17124262 16170337 15728586 17287366
MESH:D006332 Cardiomegaly valsartan 14.3219597038
MESH:D009202 Cardiomyopathies valsartan 4.1316247790
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.7215710769 19225199
MESH:D002318 Cardiovascular Diseases Arsenic 6.8115738583 19152805 17938729
MESH:D002318 Cardiovascular Diseases valsartan 6.8111230374
MESH:D002340 Carotid Artery Diseases Arsenic 3.9318022660 16973168
MESH:D002341 Carotid Artery Thrombosis Amiodarone 4.6318974383
MESH:D002386 Cataract Acetaminophen 6.6310977129
MESH:D002386 Cataract Methylnitrosourea 6.6312484553
MESH:D002471 Cell Transformation, Neoplastic Clofibrate 22.241399818
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 22.2412371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 22.2417174075 2727394 7505956 21159647
MESH:D002471 Cell Transformation, Neoplastic Estradiol 22.2418566989
MESH:D002471 Cell Transformation, Neoplastic Methylnitrosourea 22.247505956 2727394
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 22.2419524636 20056578
MESH:D002637 Chest Pain Omeprazole 4.6415447763
MESH:D054506 Chloracne marker/mechanism 17101203
MESH:D018281 Cholangiocarcinoma 3,4,5,3',4'-pentachlorobiphenyl 14.1616628245
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 14.1619052882
MESH:D018281 Cholangiocarcinoma Thioacetamide 14.1618291259
MESH:D002779 Cholestasis Cyclosporine 6.6319486331
MESH:D002779 Cholestasis pirinixic acid 6.6319176532
MESH:D002971 Cleft Lip Ethanol 3.3415513904
MESH:D002972 Cleft Palate Ethanol 5.8615513904
MESH:D002972 Cleft Palate triadimefon 5.8616781842
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8520501625
MESH:D003324 Coronary Artery Disease valsartan 3.7217719468
MESH:D023903 Coronary Restenosis arsenic trioxide 3.7512609071
MESH:D003384 Coxsackievirus Infections valsartan 5.3920392896
MESH:D019465 Craniofacial Abnormalities 3,4,5,3',4'-pentachlorobiphenyl 6.7217686920
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 6.7210525206
MESH:D019465 Craniofacial Abnormalities Benzene 6.7215643154
MESH:D019465 Craniofacial Abnormalities Ethanol 6.7210194807 15451039 15451040 19302082 11873399 11198716 15513904
MESH:D019465 Craniofacial Abnormalities triadimefon 6.7215834900 16875885
MESH:D003456 Cryptorchidism vinclozolin 3.9114966744
MESH:D003490 Cyanosis 2,4-dinitrotoluene 3.5718551238
MESH:D003556 Cystitis Cyclophosphamide 4.5217979934 18093676 17010015 11948286 16651033 16413132 18295254 16989017 12161096 15276878 15643279 10498854 10700343 12388444 18710439 18372110 18483878 12913760 18433785 16614059
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.6815213294
MESH:D003872 Dermatitis Benzene 4.3215902427
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 3.2611298694 16823706 16780908
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2018249437
MESH:D003921 Diabetes Mellitus, Experimental Cyclophosphamide 7.7615331540 10990075 11751995
MESH:D003921 Diabetes Mellitus, Experimental valsartan 7.7611508273
MESH:D003922 Diabetes Mellitus, Type 1 Cyclophosphamide 3.0718772604
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 2.0720387270
MESH:D003928 Diabetic Nephropathies Estradiol 8.0619279558
MESH:D003928 Diabetic Nephropathies valsartan 8.0611427623 18630688
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 19.4718551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 19.4712705907 16081117 11739529 11287661 11743745 19739265 17906064 16109766 18071297 14986274 18713872 11834606 10774834 19416960 16485898 14725611 16393943 16781746 19370779 19085960 12540782 15968718 12392966 11461765 12958197 16177239 12153990 10915739 19420014 16227642 19923254 10663392 19164858 17562736 2444490 11421492 17522070 15619225 14550746 12594235 11529661
MESH:D056486 Drug-Induced Liver Injury Amiodarone 19.4715265979 18218290
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 19.4719107877
MESH:D056486 Drug-Induced Liver Injury Drugs, Chinese Herbal 19.4715027814
MESH:D056486 Drug-Induced Liver Injury Ethanol 19.4711566570
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 19.4712963478
MESH:D056486 Drug-Induced Liver Injury Trichloroethylene 19.477120509
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.6319426721
MESH:D004381 Duodenal Ulcer Omeprazole 3.9017151854 16613094 15991576 21218061
MESH:D050171 Dyslipidemias Clofibrate 7.7216707586
MESH:D050171 Dyslipidemias Dietary Fats 7.7218367378
MESH:D004487 Edema pirinixic acid 2.1012083418
MESH:D004489 Edema, Cardiac 3,4,5,3',4'-pentachlorobiphenyl 5.2917686920
MESH:D016889 Endometrial Neoplasms Estradiol 2.6811473722 19148513 18566989
MESH:D004802 Eosinophilia Cyclophosphamide 3.7811006010
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.6516302075
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.2612903497
MESH:D004938 Esophageal Neoplasms Ethanol 4.2616704527
MESH:D005221 Fatigue Amphetamine 5.1419890266
MESH:D005218 Fat Necrosis Thioacetamide 5.2616456712
MESH:D005234 Fatty Liver Amiodarone 36.2214986274
MESH:D005234 Fatty Liver arsenic trioxide 36.2215073043
MESH:D005234 Fatty Liver Clofibrate 36.2219224547
MESH:D005234 Fatty Liver Cyclosporine 36.2219224547
MESH:D005234 Fatty Liver Dietary Fats 36.2219551842 18296743 17967931 19004024
MESH:D005234 Fatty Liver Diethylnitrosamine 36.2221071580 20387270
MESH:D005234 Fatty Liver Ethanol 36.2218620774 19236843 16409862
MESH:D005234 Fatty Liver pirinixic acid 36.2220131406 19236843
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.2017920746
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.8416946407 15513904 15451040 10194807
MESH:D005354 Fibrosarcoma Methylnitrosourea 4.7811555667
MESH:D005355 Fibrosis Cyclosporine 12.4112639820 12168785
MESH:D005355 Fibrosis Dietary Fats 12.4118296743
MESH:D005355 Fibrosis valsartan 12.4116893502
MESH:D005534 Foot Diseases Arsenic 5.096392382
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.8316904648
MESH:D005756 Gastritis Acetaminophen 9.5916983495
MESH:D005756 Gastritis Ethanol 9.5915046732
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.4816973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.8416417039
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.2216452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.768708960
MESH:D005910 Glioma Methylnitrosourea 3.379825942
MESH:D018316 Gliosarcoma Cyclophosphamide 5.0611389073
MESH:D015432 Glomerulonephritis, Membranoproliferative valsartan 5.1116928621
MESH:D006086 Graft vs Host Disease Cyclophosphamide 4.5911014644 16376943 15172196
MESH:D006330 Heart Defects, Congenital 3,4,5,3',4'-pentachlorobiphenyl 3.9417686920 20471113
MESH:D006333 Heart Failure Dobutamine 14.6617440445
MESH:D006333 Heart Failure Isoproterenol 14.6618097624
MESH:D006333 Heart Failure pirinixic acid 14.6620558911
MESH:D006333 Heart Failure valsartan 14.6619027736
MESH:D006402 Hematologic Diseases Benzene 4.2416183116
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.9715720958
MESH:D006467 Hemophilia A Cyclophosphamide 4.8511918545
MESH:D006501 Hepatic Encephalopathy Thioacetamide 4.1717276928 15929193 18665440
MESH:D006504 Hepatic Veno-Occlusive Disease Cyclophosphamide 5.0714986274
MESH:D006505 Hepatitis Drugs, Chinese Herbal 8.5018339527
MESH:D006505 Hepatitis Thioacetamide 8.5016456712
MESH:D006529 Hepatomegaly Amiodarone 22.5015265979
MESH:D006529 Hepatomegaly pirinixic acid 22.5016221962 19772884 19176532 18467677
MESH:D006529 Hepatomegaly propiconazole 22.5017178689 17178688
MESH:D006529 Hepatomegaly systhane 22.5017178689 17178688
MESH:D006529 Hepatomegaly triadimefon 22.5017178689 17178688
MESH:D006558 Herpes Genitalis Estradiol 4.5715709030
MESH:D006561 Herpes Simplex Etoposide 4.1110809021
MESH:D006689 Hodgkin Disease Cyclophosphamide 10.2417606976 16135485
MESH:D006689 Hodgkin Disease Etoposide 10.2415147373 18180244 16135485 17606976 16200630
MESH:D006689 Hodgkin Disease sodium arsenite 10.2412676792
MESH:D019584 Hot Flashes Estradiol 3.2917088409
MESH:D006930 Hyperalgesia Acetaminophen 6.6216870215
MESH:D006930 Hyperalgesia Ethanol 6.6218783367
MESH:D006937 Hypercholesterolemia Amiodarone 7.828137927 9751232
MESH:D006937 Hypercholesterolemia Dietary Fats 7.8221332399
MESH:D006943 Hyperglycemia pirinixic acid 2.7920558911
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.0617050553
MESH:D006948 Hyperkinesis Amphetamine 4.981977408 14960337
MESH:D006949 Hyperlipidemias Dietary Fats 3.2021332399
MESH:D006973 Hypertension Arsenic 14.3916076760 11953799 9931084
MESH:D006973 Hypertension Benzene 14.3917940673
MESH:D006973 Hypertension Cyclosporine 14.3910903974
MESH:D006973 Hypertension Phenylephrine 14.398949925 12717712
MESH:D006973 Hypertension valsartan 14.3910903974 18344623 11427623 20102058 12850387 16475468 18390891 12692753
MESH:D006974 Hypertension, Malignant valsartan 5.9511560862
MESH:D006984 Hypertrophy therapeutic 12791704
MESH:D006984 Hypertrophy Isoproterenol 9.6512791704
MESH:D006984 Hypertrophy Phenylephrine 9.6518502941 12791704
MESH:D006987 Hypesthesia Arsenic 5.0916093927
MESH:D007022 Hypotension Isoproterenol 4.386740701
MESH:D007037 Hypothyroidism Amiodarone 10.1418020914 17991464
MESH:D007037 Hypothyroidism Propylthiouracil 10.148137927 18031379
MESH:D007154 Immune System Diseases Cyclophosphamide 4.8716076520
MESH:D007248 Infertility, Male Cyclophosphamide 13.597193160 16517039
MESH:D007248 Infertility, Male Methylnitrosourea 13.597193160
MESH:D007248 Infertility, Male sodium arsenite 13.5912646999 15346721
MESH:D007248 Infertility, Male vinclozolin 13.5916467254
MESH:D007249 Inflammation Dietary Fats 4.2920412841
MESH:D007249 Inflammation Diethylnitrosamine 4.2918785209
MESH:D007333 Insulin Resistance Dietary Fats 10.5318457598 11836018
MESH:D007333 Insulin Resistance Estradiol 10.5316393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 10.5316306350
MESH:D007569 Jaw Abnormalities Ethanol 9.3715513904
MESH:D007569 Jaw Abnormalities triadimefon 9.3715834900 15992940
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.9815604871
MESH:D007642 Keratosis Arsenic 4.5416930632 12749816
MESH:D007674 Kidney Diseases Acetaminophen 16.1715629191 12587719
MESH:D007674 Kidney Diseases Cyclosporine 16.1718776723 8314463 10903974
MESH:D007674 Kidney Diseases Estradiol 16.1715618244
MESH:D007674 Kidney Diseases sodium arsenite 16.1720008137
MESH:D007674 Kidney Diseases valsartan 16.1712164870 10903974 16893502
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 10.2416705839
MESH:D007680 Kidney Neoplasms Cyclosporine 10.2412371664
MESH:D007680 Kidney Neoplasms Estradiol 10.2415610895
MESH:D007859 Learning Disorders Ethanol 8.5815451040
MESH:D007859 Learning Disorders sevoflurane 8.5819212262
MESH:D016773 Leishmaniasis, Cutaneous Omeprazole 3.7319248655
MESH:D007938 Leukemia arsenic trioxide 9.2415070760
MESH:D007938 Leukemia Benzene 9.2418335105 17119257 14694614 15935818
MESH:D007938 Leukemia Cyclophosphamide 9.2410602166
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Cyclophosphamide 6.3317802794 18172266 17658394 18587576 17296974 17008537
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Drugs, Chinese Herbal 6.3315802533
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.3917077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.8516972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 7.4914633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Cyclophosphamide 7.4910373061
MESH:D007951 Leukemia, Myeloid arsenic trioxide 8.3519077051
MESH:D007951 Leukemia, Myeloid Benzene 8.3517506065
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.7817050201 16968895 19850784 16467208 20471514
MESH:D015470 Leukemia, Myeloid, Acute Benzene 3.7819478238
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 6.7717339181
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 6.7715622746 15748426 12679006 11161223 17869043 19225113 16823087 17217047 9834237 16966277 17712046 11468182 12712474 16330433 17649720 16331271 19075265 12018890 16891316 16112521 19035177 19642359 15213294 15336539 17107899
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.9216882451
MESH:D007970 Leukopenia Cyclophosphamide 4.5110052129 11830472
MESH:D007984 Leydig Cell Tumor vinclozolin 4.2816417039
MESH:D017880 Limb Deformities, Congenital Ethanol 7.5517676605
MESH:D017880 Limb Deformities, Congenital Methylnitrosourea 7.5515526292
MESH:D008064 Lipidoses Amiodarone 3.1815342952 17567588
MESH:D008103 Liver Cirrhosis Dietary Fats 13.6818296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 13.6820032147 18407596 18522880 19638242 18665156
MESH:D008103 Liver Cirrhosis Drugs, Chinese Herbal 13.6817163593
MESH:D008103 Liver Cirrhosis Ethanol 13.6815289165
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.6418295389
MESH:D008106 Liver Cirrhosis, Experimental Drugs, Chinese Herbal 7.8417881167 17666798 15754396 15383259 18237412 15849816 18567088 17036385 12632512 18606216 15641146 16610055 15339415 15744066 17629604 15763062 15864749 18371158 15818738 17348192
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 7.8414716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 7.8418166357
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 7.8415474484
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 7.8415158331 12531686 18031379 18263696 18458672 17127702 15465738 10677585 16511523 12175628 16489207 12085344 15716488 12679928 16248980 18606216 18615449 14739098 12557150 15362042 17292413 16097051 18380797 15334695 11172339 18416461 11682029 16098781 18032466 11481614 15288472 15288473 15095483 15075984 18295389 12891558 16126171 17629604 18395095 15316131 17355460 16343077 15474484 17050028 15078482
MESH:D008106 Liver Cirrhosis, Experimental valsartan 7.8415619341 16872305 15504291
MESH:D008107 Liver Diseases Acetaminophen 17.2612587719 16611625 11587558 19460945 16610002 12969438 19784758 19014921
MESH:D008107 Liver Diseases Arsenic 17.2611134558
MESH:D008107 Liver Diseases Diethylnitrosamine 17.2617034775
MESH:D008107 Liver Diseases Drugs, Chinese Herbal 17.2617207593
MESH:D008107 Liver Diseases propiconazole 17.2619363144
MESH:D008107 Liver Diseases Thioacetamide 17.2618374380 16337175 15158337
MESH:D008107 Liver Diseases triadimefon 17.2619363144
MESH:D008108 Liver Diseases, Alcoholic Ethanol 4.2117207112 17347304
MESH:D017114 Liver Failure, Acute Acetaminophen 8.3316871587 17185352
MESH:D017114 Liver Failure, Acute Thioacetamide 8.3315313186 15633222 12479984 17276928
MESH:D008113 Liver Neoplasms Arsenic 26.3416368122
MESH:D008113 Liver Neoplasms arsenic trioxide 26.3414682389
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 26.3421295105 19389873
MESH:D008113 Liver Neoplasms Diethylnitrosamine 26.342422723 20452335 10737359 19638242 20492335 18648771 20405173 20137499 19073162 12112319 21047994 18644402 20118626 21278145 21071580 16942905 18978307 19690152 21167192 20101389 19642983 18977376 19256749 15175105 20501860 19427195 19833225 12771043 9163691 19812893 19551842 19426721 2862719 19254457 19090486 19499222 20583210 19294768 19850985 18754104 15885732 19255062 19996281 20434301
MESH:D008113 Liver Neoplasms Drugs, Chinese Herbal 26.3418339527
MESH:D008113 Liver Neoplasms pirinixic acid 26.3416377806 20007298 15890375
MESH:D008113 Liver Neoplasms propiconazole 26.3419028983
MESH:D008113 Liver Neoplasms sodium arsenite 26.3415276417 16712894
MESH:D008113 Liver Neoplasms triadimefon 26.3419028983
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 28.1620377131
MESH:D008114 Liver Neoplasms, Experimental Benzene 28.1612562636
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 28.1618164116
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 28.1618282651 18079962 17854601 19126423 21159647 18775883 19539802 18253720 16267830 18164116 19009564 18544905 16842330 17942915 19004024 3124819 18308698 17174075 19519916 2563599 9362446 18093689
MESH:D008114 Liver Neoplasms, Experimental propiconazole 28.1617178689
MESH:D008114 Liver Neoplasms, Experimental systhane 28.1617178689
MESH:D008114 Liver Neoplasms, Experimental triadimefon 28.1617178689
MESH:D008114 Liver Neoplasms, Experimental Trichloroethylene 28.167955063
MESH:D008133 Long QT Syndrome Amiodarone 11.7415350150 11989578 17391786
MESH:D008133 Long QT Syndrome arsenic trioxide 11.7415213294
MESH:D008133 Long QT Syndrome Dobutamine 11.7419353679
MESH:D038061 Lower Extremity Deformities, Congenital Methylnitrosourea 5.0216080182
MESH:D008171 Lung Diseases Amiodarone 10.7512587719
MESH:D008171 Lung Diseases Dobutamine 10.7516638327
MESH:D008171 Lung Diseases sodium arsenite 10.7519095001
MESH:D017563 Lung Diseases, Interstitial Amiodarone 9.9218516814
MESH:D017563 Lung Diseases, Interstitial Benzene 9.9214698565
MESH:D008175 Lung Neoplasms Arsenic 9.6317976673 19168569 17306315
MESH:D008175 Lung Neoplasms arsenic trioxide 9.6319825857 11798837
MESH:D008175 Lung Neoplasms Benzene 9.6312562636
MESH:D008175 Lung Neoplasms Diethylnitrosamine 9.6320970405 6695378 20512841 21163286
MESH:D008175 Lung Neoplasms Drugs, Chinese Herbal 9.6318339527
MESH:D008175 Lung Neoplasms Methylnitrosourea 9.6318062963
MESH:D008175 Lung Neoplasms sodium arsenite 9.6315276417 17306315 16712894 17077188 19931552
MESH:D008223 Lymphoma Benzene 15.3017119257 17584886
MESH:D008223 Lymphoma Cyclophosphamide 15.3012854902
MESH:D008223 Lymphoma Etoposide 15.3012556972 12854902
MESH:D008223 Lymphoma Methylnitrosourea 15.3016257854 11418001
MESH:D016393 Lymphoma, B-Cell Cyclophosphamide 9.2616675587
MESH:D016393 Lymphoma, B-Cell Methylnitrosourea 9.2614633661
MESH:D008228 Lymphoma, Non-Hodgkin Cyclophosphamide 3.8011911406
MESH:D015674 Mammary Neoplasms, Animal Benzene 3.9912562636
MESH:D008325 Mammary Neoplasms, Experimental Benzene 11.9311921183
MESH:D008325 Mammary Neoplasms, Experimental Drugs, Chinese Herbal 11.9314758024
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 11.9316891317 11807958 17203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental Methylnitrosourea 11.9315313902 19196723 11751437 17020996 15113128 15688392 10767621 17131329 10838139 16944150 16619500 14633655 11807958 16827153 14999141 12931682 16051031
MESH:D020149 Manganese Poisoning Estradiol 4.0219453300
MESH:D008545 Melanoma sodium arsenite 1.9719082730 16487513
MESH:D008546 Melanoma, Experimental Acetaminophen 9.3619513568
MESH:D008546 Melanoma, Experimental Cyclophosphamide 9.3616388313
MESH:D008569 Memory Disorders Ethanol 8.5418411066 15451040
MESH:D008569 Memory Disorders sevoflurane 8.5419212262
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.3216801185
MESH:D009041 Motion Sickness Dextroamphetamine 5.061613127
MESH:D009101 Multiple Myeloma arsenic trioxide 6.4119417148 15949261 19549372 11468182 14977855
MESH:D009101 Multiple Myeloma Benzene 6.4117119195
MESH:D009135 Muscular Diseases pirinixic acid 3.0616239165
MESH:D009181 Mycoses Amiodarone 4.4417974566 12754197
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.2118349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 2.8716105982 16882451
MESH:D009203 Myocardial Infarction marker/mechanism 19027736
MESH:D009203 Myocardial Infarction Isoproterenol 5.3516538859 16584858 16697266 19172585 19595682 15740881 17052832
MESH:D009203 Myocardial Infarction pirinixic acid 5.3519151258
MESH:D017202 Myocardial Ischemia Arsenic 8.5415371236
MESH:D017202 Myocardial Ischemia Dobutamine 8.5412447174
MESH:D015428 Myocardial Reperfusion Injury Estradiol 7.0916810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 7.0916411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.4118551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.5316624393
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.373581430 9029167
MESH:D009369 Neoplasms Cyclophosphamide 13.2218854779
MESH:D009369 Neoplasms Methylnitrosourea 13.2215533788
MESH:D009369 Neoplasms pirinixic acid 13.2217405874
MESH:D009369 Neoplasms sodium arsenite 13.2211559025
MESH:D009369 Neoplasms Trichloroethylene 13.2211911487
MESH:D009374 Neoplasms, Experimental Methylnitrosourea 7.9312696579
MESH:D009374 Neoplasms, Experimental sodium arsenite 7.9320056578
MESH:D009389 Neovascularization, Pathologic Estradiol 3.2817289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.9817954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 2.9019348381 18481113
MESH:D009421 Nervous System Malformations Estradiol 3.2216427766 11399458
MESH:D009436 Neural Tube Defects Arsenic 14.8916620997
MESH:D009436 Neural Tube Defects arsenic trioxide 14.8910525206
MESH:D009436 Neural Tube Defects Benzene 14.8915643154
MESH:D009436 Neural Tube Defects sodium arsenite 14.8912854658
MESH:D009442 Neurilemmoma Methylnitrosourea 5.0311555667
MESH:D009447 Neuroblastoma Cyclophosphamide 3.408761367 15176712 16115947
MESH:D019636 Neurodegenerative Diseases Acetaminophen 12.0318514411
MESH:D019636 Neurodegenerative Diseases Amphetamine 12.0315183010
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 12.0320387270
MESH:D017599 Neuroectodermal Tumors Cyclophosphamide 4.4412837982 8761367
MESH:D020078 Neurogenic Inflammation Arsenic 3.9617056641
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.6520387270
MESH:D009503 Neutropenia Cyclophosphamide 3.918291058
MESH:D052556 Niemann-Pick Disease, Type C Clofibrate 4.499802331
MESH:D009765 Obesity Dietary Fats 3.9916723640 21332399 18457598 17217161 18674790 20132043 20518802 11836018 19632207
MESH:D009765 Obesity pirinixic acid 3.9920558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 7.8512819281 16049721
MESH:D009784 Occupational Diseases Benzene 7.8515576619 16737584 15612468 15913788 17119257 17178637 15727169 15935809 17479406
MESH:D009845 Oligospermia Cyclophosphamide 4.2616517039
MESH:D015663 Osteoporosis, Postmenopausal Drugs, Chinese Herbal 4.5716548355
MESH:D010051 Ovarian Neoplasms Arsenic 13.2517306315
MESH:D010051 Ovarian Neoplasms arsenic trioxide 13.2516624393 19769630 12452020
MESH:D010051 Ovarian Neoplasms Benzene 13.2512562636
MESH:D010051 Ovarian Neoplasms Estradiol 13.2519401270
MESH:D010051 Ovarian Neoplasms sodium arsenite 13.2515276417 17306315
MESH:D010146 Pain Acetaminophen 5.6516870215
MESH:D010146 Pain Cyclophosphamide 5.6512161096 18093676
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 18.1415580305
MESH:D010190 Pancreatic Neoplasms Cyclophosphamide 18.1411332152
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 18.1416540662
MESH:D010190 Pancreatic Neoplasms Ethanol 18.1412384795
MESH:D010190 Pancreatic Neoplasms Etoposide 18.1419003803
MESH:D010190 Pancreatic Neoplasms Methylnitrosourea 18.1416965848
MESH:D010235 Paraganglioma arsenic trioxide 3.7419927285
MESH:D010523 Peripheral Nervous System Diseases Arsenic 3.7516093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 4.546392382 15371236 16905509
MESH:D011230 Precancerous Conditions Cyclosporine 7.6712371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 7.672563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Cyclophosphamide 3.5421297632
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 3.4519015723 18042343 18220299
MESH:D011469 Prostatic Diseases vinclozolin 4.4818220299
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.4820887781
MESH:D011471 Prostatic Neoplasms Arsenic 2.0216140617
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.0219131511
MESH:D011471 Prostatic Neoplasms Cyclophosphamide 2.0217136230
MESH:D011471 Prostatic Neoplasms Estradiol 2.0216740699
MESH:D011471 Prostatic Neoplasms Etoposide 2.0217172428
MESH:D011471 Prostatic Neoplasms Methylnitrosourea 2.0212376480 15682402
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.0216039940
MESH:D011472 Prostatitis vinclozolin 4.4818629315
MESH:D011507 Proteinuria Arsenic 8.3521343184
MESH:D011507 Proteinuria valsartan 8.3512164870 18344623 17664856
MESH:D011565 Psoriasis Cyclosporine 2.0616882103
MESH:D011654 Pulmonary Edema Isoproterenol 4.7910903255
MESH:D011658 Pulmonary Fibrosis Amiodarone 11.7512832656 12490602 11597910
MESH:D011658 Pulmonary Fibrosis Cyclophosphamide 11.7516636934
MESH:D011658 Pulmonary Fibrosis Drugs, Chinese Herbal 11.7516987627
MESH:D011658 Pulmonary Fibrosis valsartan 11.7517241526
MESH:D012003 Rectal Fistula Drugs, Chinese Herbal 5.5015043669
MESH:D015427 Reperfusion Injury pirinixic acid 2.1519058328
MESH:D012162 Retinal Degeneration Methylnitrosourea 4.0718172121 18155124
MESH:D012175 Retinoblastoma Methylnitrosourea 5.0311555667
MESH:D012221 Rhinitis, Allergic, Perennial Drugs, Chinese Herbal 4.8115015336
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 9.0216646077
MESH:D012512 Sarcoma, Ewing's Etoposide 9.0214601052
MESH:D012595 Scleroderma, Systemic Cyclophosphamide 4.4016636934
MESH:D012640 Seizures 2,4-dinitrotoluene 5.0718551238
MESH:D012640 Seizures Ethanol 5.079754883
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 4.6318724381
MESH:D012852 Sinusitis Phenylephrine 4.257327846
MESH:D012871 Skin Diseases Arsenic 2.6218709164 17548696 16353154 19834688 17938729 6392382 16702368 16759981 17050553 17453740 15952646
MESH:D012878 Skin Neoplasms Arsenic 5.1917029826 15504454 17976673 19538983 16251483 17050553
MESH:D012878 Skin Neoplasms sodium arsenite 5.1918572023 19524636
OMIM:102530 SPERMATOGENIC FAILURE 6 Cyclophosphamide 5.0616517039
MESH:D016135 Spinal Dysraphism sodium arsenite 3.4412854658
MESH:D019956 Stereotypic Movement Disorder Amphetamine 5.961977408
MESH:D013272 Stomach Diseases Omeprazole 4.1618545984
MESH:D013274 Stomach Neoplasms arsenic trioxide 7.5617007042
MESH:D013274 Stomach Neoplasms Benzene 7.5612562636
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 7.5618456281
MESH:D013274 Stomach Neoplasms Drugs, Chinese Herbal 7.5618339527
MESH:D013274 Stomach Neoplasms Ethanol 7.5618456281
MESH:D013274 Stomach Neoplasms Methylnitrosourea 7.5616257854 18593901 15930296
MESH:D013276 Stomach Ulcer Amiodarone 9.8818087811
MESH:D013276 Stomach Ulcer Ethanol 9.8811906479 17189318 16755016 9211565 17918041 9562338
MESH:D013276 Stomach Ulcer Omeprazole 9.8810750652 16755016 17977527 18237397 11906479 15991576
MESH:D013345 Subarachnoid Hemorrhage Drugs, Chinese Herbal 5.3017634840
MESH:D013375 Substance Withdrawal Syndrome Ethanol 3.869754883
MESH:D015173 Supratentorial Neoplasms Cyclophosphamide 4.6012837982
MESH:D013610 Tachycardia Amiodarone 3.8611238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 3.7619225199
MESH:D013953 Thymus Neoplasms Benzene 10.7110850423
MESH:D013953 Thymus Neoplasms Methylnitrosourea 10.7111418001
MESH:D013959 Thyroid Diseases Amiodarone 4.2919731979
MESH:D013964 Thyroid Neoplasms arsenic trioxide 18.8419014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 18.847505956
MESH:D013964 Thyroid Neoplasms Methylnitrosourea 18.843078959 7505956
MESH:D013964 Thyroid Neoplasms Propylthiouracil 18.8415710170
MESH:D013964 Thyroid Neoplasms triadimefon 18.8417178689
MESH:D013971 Thyrotoxicosis Amiodarone 4.4219584973 18020914
MESH:D013978 Tibial Fractures Estradiol 4.2219048282
MESH:D016171 Torsades de Pointes Amiodarone 14.7717467628 11989578
MESH:D016171 Torsades de Pointes arsenic trioxide 14.7715213294
MESH:D016171 Torsades de Pointes Dobutamine 14.7719353679
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 13.7316049721
MESH:D001749 Urinary Bladder Neoplasms Arsenic 13.7311144890 19429237 15987713 18640142 19322015 17306315 17976673
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 13.7320435036 12845720 12973940 11780464
MESH:D001749 Urinary Bladder Neoplasms Cyclophosphamide 13.7314692829
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 13.7316712894 17306315 11723127 16452187
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 3.8610091137
MESH:D014581 Urticaria Acetaminophen 2.5610982225
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 3.3711813266
MESH:D014594 Uterine Neoplasms Benzene 3.9012562636
MESH:D014605 Uveitis Cyclosporine 3.521336536
MESH:D014652 Vascular Diseases Arsenic 10.3417056641
MESH:D014652 Vascular Diseases sodium arsenite 10.3417056641
MESH:D018487 Ventricular Dysfunction, Left Isoproterenol 4.6818097624
MESH:D020257 Ventricular Remodeling Isoproterenol 11.4918097624
MESH:D020257 Ventricular Remodeling valsartan 11.4919027736
MESH:D015430 Weight Gain Dietary Fats 3.3616723640
MESH:D014947 Wounds and Injuries Drugs, Chinese Herbal 4.1716313111
MESH:D014985 Xerophthalmia Cyclosporine 3.9817120751
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA26871
    • No data
    Releated disease ID Related disease Name
    PA447278Depression
    Releated drug ID Related drug Name
    PA164743471adenosine triphosphate
    PA449233desipramine
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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