AutismKB 2.0

Annotation Detail for DCAF12L1


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Basic Information Top
Gene Symbol:DCAF12L1 ( KIAA1892L,WDR40B )
Gene Full Name: DDB1 and CUL4 associated factor 12-like 1
Band: Xq25
Quick LinksEntrez ID:139170; OMIM: NA; Uniprot ID:DC121_HUMAN; ENSEMBL ID: ENSG00000198889; HGNC ID: 29395
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of DCAF12L1 mRNAdecreases expression 18648102
C006253 pirinixic acid pirinixic acid results in increased expression of DCAF12L1 mRNAincreases expression 18301758
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055371 Acute Lung Injury pirinixic acid 3.7218653653
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 3.003712494
MESH:D018248 Adenoma, Liver Cell pirinixic acid 4.3716434500
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 6.0911289319 1440618
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.7019483382
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 1.787296757 3581430
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.867296757
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 3.087505956
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 9.0719486331 9022650
MESH:D002779 Cholestasis pirinixic acid 9.0719176532
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 3.5514531868 8156756 11906362 12868966 2524372 18759878 8970840 11298694
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.6118249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 4.103621924 2952479
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 2.069328219 18289764 18692083 16192314 1440618 18648102 6482804 9022650 8291058 6679447 7440962 9653073 11289319
MESH:D004487 Edema pirinixic acid 3.0212083418
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.193581430
MESH:D005234 Fatty Liver pirinixic acid 3.3119236843 20131406
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 6.096705139
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.647505956
MESH:D006333 Heart Failure pirinixic acid 2.8120558911
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 4.196705139
MESH:D006529 Hepatomegaly pirinixic acid 3.7619772884 19176532 16221962 18467677
MESH:D006943 Hyperglycemia pirinixic acid 3.6920558911
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.7015034207
MESH:D007333 Insulin Resistance pirinixic acid 2.9316306350
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 6.098074119 9022650
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 3.406582329
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.479327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008113 Liver Neoplasms pirinixic acid 1.9515890375 16377806 20007298
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 2.806587162 598648 1399818 3712494
MESH:D009135 Muscular Diseases pirinixic acid 4.2716239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.3019151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.3316411023
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.623581430
MESH:D009369 Neoplasms pirinixic acid 2.1417405874
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 3.216679447
MESH:D009765 Obesity pirinixic acid 1.9020558911
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.924026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 6.093988306
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 4.247296757
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 5.546228378
MESH:D015427 Reperfusion Injury pirinixic acid 2.5819058328
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.743692021
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 3.266582329 6587162 1399818 3712494 7505956
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 2.428074119
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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