AutismKB 2.0

Annotation Detail for CSF2RB


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Basic Information Top
Gene Symbol:CSF2RB ( CD131,CDw131,IL3RB,IL5RB )
Gene Full Name: colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
Band: 22q12.3
Quick LinksEntrez ID:1439; OMIM: 138981; Uniprot ID:IL3RB_HUMAN; ENSEMBL ID: ENSG00000100368; HGNC ID: 2436
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04630Jak-STAT signaling pathway
hsa04060Cytokine-cytokine receptor interaction
hsa04210Apoptosis
Pathway IDPathway Name
Signaling in Immune system
Pathway IDPathway Name
200015GMCSF-mediated signaling events
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CSF2RB mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in increased expression of CSF2RB mRNAincreases expression 15070760
C055162 clopidogrel clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of CSF2RB mRNA]decreases reaction|increases expression 19172522
D003474 Curcumin Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CSF2RB mRNA]decreases reaction|increases expression 18200517
D003907 Dexamethasone Dexamethasone results in decreased expression of CSF2RB mRNAdecreases expression 11758170
D004958 Estradiol Estradiol results in increased expression of CSF2RB mRNAincreases expression 12469912
D005419 Flavonoids Flavonoids results in increased expression of CSF2RB mRNAincreases expression 15465739
D006581 Hexachlorobenzene Hexachlorobenzene results in increased expression of CSF2RB mRNAincreases expression 15159207
D008070 Lipopolysaccharides clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of CSF2RB mRNA]decreases reaction|increases expression 19172522
C006253 pirinixic acid pirinixic acid results in increased expression of CSF2RB mRNAincreases expression 18301758
D010936 Plant Extracts Plant Extracts results in increased expression of CSF2RB mRNAincreases expression 15465739
C025299 polyphenols polyphenols results in increased expression of CSF2RB mRNAincreases expression 15465739
C017947 sodium arsenite sodium arsenite results in increased expression of CSF2RB mRNAincreases expression 20308225
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of CSF2RB mRNAincreases expression 11879969
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of CSF2RB proteinincreases expression 11879969
D013864 Thioglycolates CSF2RB protein affects the susceptibility to Thioglycolatesaffects response to substance 8916939
D014028 Tobacco Smoke Pollution Tobacco Smoke Pollution results in decreased expression of CSF2RB mRNAdecreases expression 18087596
D014302 Trinitrobenzenesulfonic Acid Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CSF2RB mRNA]decreases reaction|increases expression 18200517
D014302 Trinitrobenzenesulfonic Acid Trinitrobenzenesulfonic Acid results in increased expression of CSF2RB mRNAincreases expression 18200517
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.8411752688 15322242 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.5518287403
MESH:D054058 Acute Coronary Syndrome clopidogrel 5.9919106084
MESH:D055371 Acute Lung Injury Lipopolysaccharides 8.9811850527 18653653
MESH:D055371 Acute Lung Injury pirinixic acid 8.9818653653
MESH:D000210 Acute-Phase Reaction Thioglycolates 6.349464241
MESH:D000230 Adenocarcinoma arsenic trioxide 4.3819825857 11798837
MESH:D000230 Adenocarcinoma Estradiol 4.3811473722
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Tobacco Smoke Pollution 5.5315814487
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.8716434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.8716835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.7015276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.9017306315 16712894
MESH:D019973 Alcohol-Related Disorders Curcumin 5.0817887948
MESH:D000544 Alzheimer Disease Curcumin 4.6015590663
MESH:D000544 Alzheimer Disease Plant Extracts 4.6016962711
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9311748828
MESH:D001169 Arthritis, Experimental Dexamethasone 7.8017659584
MESH:D001169 Arthritis, Experimental Plant Extracts 7.8014686799
MESH:D001172 Arthritis, Rheumatoid Curcumin 5.0616807698
MESH:D001172 Arthritis, Rheumatoid Tobacco Smoke Pollution 5.0619898480
MESH:D050197 Atherosclerosis Curcumin 3.3118704882
MESH:D001327 Autoimmune Diseases Curcumin 4.4819761891
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 15.1816206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 15.1819483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 15.1812125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7515746008
MESH:D002545 Brain Ischemia Curcumin 10.4616770732
MESH:D002545 Brain Ischemia Plant Extracts 10.4616041641
MESH:D001932 Brain Neoplasms Curcumin 3.9217596214
MESH:D001943 Breast Neoplasms Curcumin 2.0019250217 16243823 18593918 18462866
MESH:D001943 Breast Neoplasms Estradiol 2.0016675129 12948864 17261762 17289903 19861407 14630087 17018787 18497071
MESH:D001943 Breast Neoplasms Hexachlorobenzene 2.0012709520 15061365
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.0020435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.3111589617
MESH:D002057 Burns, Chemical Plant Extracts 5.349625245
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.4516111702
MESH:D002277 Carcinoma Curcumin 8.2318593918
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 8.2316835633
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 6.6116217749 15073043 15553829 14691202 11135700
MESH:D006528 Carcinoma, Hepatocellular Estradiol 6.6116924424
MESH:D006528 Carcinoma, Hepatocellular Plant Extracts 6.6118834353
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 6.6116507464 15276417 17306315
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 5.9018414057
MESH:D002289 Carcinoma, Non-Small-Cell Lung Tobacco Smoke Pollution 5.9011212258
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.8719014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.1012490120
MESH:D002294 Carcinoma, Squamous Cell Curcumin 7.7018462866
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 7.7018572023
MESH:D002294 Carcinoma, Squamous Cell Tobacco Smoke Pollution 7.7011212258
MESH:D006332 Cardiomegaly Plant Extracts 6.9417645561
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.9418850075 16120746 18670907
MESH:D002318 Cardiovascular Diseases clopidogrel 4.5920180610
MESH:D002471 Cell Transformation, Neoplastic Estradiol 6.6918566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 6.6919524636 20056578
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1416835633
MESH:D002779 Cholestasis pirinixic acid 2.8119176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0916354765 15340226 12621046 8697196 15668235
MESH:D003092 Colitis Curcumin 9.9118200517 16804969 16782535
MESH:D003092 Colitis Trinitrobenzenesulfonic Acid 9.9118023891 16474422 16867261 16782535 17991707 18200517 11698051 16804969 17936198
MESH:D003093 Colitis, Ulcerative Trinitrobenzenesulfonic Acid 3.4317276891
MESH:D003103 Coloboma Curcumin 4.5318809619
MESH:D003110 Colonic Neoplasms Curcumin 5.9819359593 16340194
MESH:D003110 Colonic Neoplasms Dexamethasone 5.9815824018
MESH:D003110 Colonic Neoplasms polyphenols 5.9816293270
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0414669216 17141729
MESH:D016510 Corneal Neovascularization Curcumin 4.8818497527
MESH:D023903 Coronary Restenosis arsenic trioxide 4.1712609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.8110525206
MESH:D019465 Craniofacial Abnormalities Dexamethasone 3.8117728286
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.8110048152 15322242 20055451
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.0815213294
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 3.3912438553
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4118249437
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 4.3918403477
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.3917107852
MESH:D003928 Diabetic Nephropathies Curcumin 15.0618204486
MESH:D003928 Diabetic Nephropathies Estradiol 15.0619279558
MESH:D003928 Diabetic Nephropathies Plant Extracts 15.0619706694
MESH:D003967 Diarrhea Dexamethasone 3.687237001
MESH:D056486 Drug-Induced Liver Injury polyphenols 3.9619370779
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.9620420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7411462148
MESH:D004381 Duodenal Ulcer Curcumin 4.0317351913
MESH:D004485 Eczema Dexamethasone 4.4412438553
MESH:D004487 Edema Dexamethasone 16.3319703484
MESH:D004487 Edema pirinixic acid 16.3312083418
MESH:D004487 Edema Plant Extracts 16.3312787963
MESH:D004487 Edema Tetrachlorodibenzodioxin 16.3311000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.9016714409 15322242 18230668
MESH:D016889 Endometrial Neoplasms Estradiol 2.9711473722 19148513 18566989
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.009294722 10568697
MESH:D004719 Endomyocardial Fibrosis Plant Extracts 5.6815268973
MESH:D019446 Endotoxemia Lipopolysaccharides 4.3915328337 15821434 17637181
MESH:D004827 Epilepsy Plant Extracts 3.7219439326 19700373
MESH:D004938 Esophageal Neoplasms arsenic trioxide 2.3012903497
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.0011564622
MESH:D005234 Fatty Liver arsenic trioxide 18.7015073043
MESH:D005234 Fatty Liver Curcumin 18.7019297423
MESH:D005234 Fatty Liver pirinixic acid 18.7020131406 19236843
MESH:D005234 Fatty Liver Plant Extracts 18.7015975614
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.4411858732
MESH:D005334 Fever Lipopolysaccharides 3.9911852909 9205823
MESH:D005355 Fibrosis Curcumin 14.8718705752
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 14.8720067830
MESH:D005355 Fibrosis Trinitrobenzenesulfonic Acid 14.8717994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.2416904648
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.6818462866
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.6716452187
MESH:D005909 Glioblastoma Curcumin 3.4617596214
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5910696789
MESH:D006258 Head and Neck Neoplasms Curcumin 3.6418462866 18829502
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.3211294989 10048152
MESH:D006333 Heart Failure pirinixic acid 7.2020558911
MESH:D006333 Heart Failure Plant Extracts 7.2018097624
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 4.3616366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3211000095
MESH:D006529 Hepatomegaly pirinixic acid 8.2216221962 18467677 19176532 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 8.2215340226 16120746 12621046
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 5.0317701891
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 3.067520565
MESH:D006558 Herpes Genitalis Estradiol 5.0315709030
MESH:D006561 Herpes Simplex Plant Extracts 4.6210715843
MESH:D015658 HIV Infections Plant Extracts 3.6712878215
MESH:D006689 Hodgkin Disease sodium arsenite 3.1312676792
MESH:D019584 Hot Flashes Estradiol 10.3417088409
MESH:D019584 Hot Flashes Plant Extracts 10.3416566672 17454163 14716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.058697196 15340226 16959395 18606429 16354765
MESH:D006937 Hypercholesterolemia Curcumin 4.0318704882
MESH:D006943 Hyperglycemia pirinixic acid 3.1620558911
MESH:D020138 Hyperhomocysteinemia Plant Extracts 4.4416484555
MESH:D006949 Hyperlipidemias Plant Extracts 4.4515975614 15268973
MESH:D006973 Hypertension Dexamethasone 5.2317042910
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.2318850075 18670907
MESH:D007248 Infertility, Male sodium arsenite 2.9715346721 12646999
MESH:D007249 Inflammation Curcumin 28.5816956363 17151092 18403477
MESH:D007249 Inflammation Dexamethasone 28.5811099482 8960868
MESH:D007249 Inflammation Flavonoids 28.5817296493
MESH:D007249 Inflammation Lipopolysaccharides 28.5817963957 17237260 17255318 12878042 9205823
MESH:D007249 Inflammation Plant Extracts 28.5816366677 19332304 15997105 12787963
MESH:D007249 Inflammation polyphenols 28.5816366677
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 28.5812200463 12878042
MESH:D007249 Inflammation Tobacco Smoke Pollution 28.5818590791
MESH:D015212 Inflammatory Bowel Diseases Curcumin 6.6618596194 18200517
MESH:D015212 Inflammatory Bowel Diseases Trinitrobenzenesulfonic Acid 6.6618200517
MESH:D007333 Insulin Resistance Estradiol 7.1516627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 7.1516306350
MESH:D007410 Intestinal Diseases Trinitrobenzenesulfonic Acid 4.5917994277
MESH:D007414 Intestinal Neoplasms Curcumin 10.0510783313
MESH:D007414 Intestinal Neoplasms Plant Extracts 10.0512351151 12584176 12628509
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.6117255318
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.3216580747
MESH:D007674 Kidney Diseases Estradiol 6.0615618244
MESH:D007674 Kidney Diseases sodium arsenite 6.0620008137
MESH:D007680 Kidney Neoplasms Estradiol 2.9615610895
MESH:D007889 Leiomyoma Curcumin 4.5518555241
MESH:D007938 Leukemia arsenic trioxide 6.4815070760
MESH:D007938 Leukemia Curcumin 6.4818462866
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 9.7017077332 12560223
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 9.7016106398
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.3016972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.4114633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.7419077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1319850784 16467208 16968895 17050201 20471514
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.2016823087 15622746 16891316 17869043 15213294 12018890 17649720 19225113 12712474 16966277 16112521 12679006 17107899 11161223 16330433 17217047 15336539 19642359 11468182 19035177 16331271 17712046 15748426 9834237 19075265
MESH:D015458 Leukemia, T-Cell arsenic trioxide 11.6616882451
MESH:D015458 Leukemia, T-Cell Curcumin 11.6616106398
MESH:D007970 Leukopenia Lipopolysaccharides 4.6915821434
MESH:D008103 Liver Cirrhosis Plant Extracts 3.7217157831
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 10.9117355460 18705752 18006644
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 10.9116718785
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 10.9114716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 10.9112878042
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 10.9115474484
MESH:D008106 Liver Cirrhosis, Experimental Plant Extracts 10.9115479170
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 10.9112878042
MESH:D008107 Liver Diseases Curcumin 6.7916956363
MESH:D008107 Liver Diseases Plant Extracts 6.7917034775
MESH:D008107 Liver Diseases polyphenols 6.7916698588
MESH:D008113 Liver Neoplasms arsenic trioxide 14.1714682389
MESH:D008113 Liver Neoplasms pirinixic acid 14.1715890375 20007298 16377806
MESH:D008113 Liver Neoplasms Plant Extracts 14.1719168119
MESH:D008113 Liver Neoplasms sodium arsenite 14.1715276417 16712894
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 14.1716984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 9.8920377131
MESH:D008114 Liver Neoplasms, Experimental Hexachlorobenzene 9.891423854
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 9.8912151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.3315213294
MESH:D008171 Lung Diseases sodium arsenite 3.1619095001
MESH:D055370 Lung Injury Lipopolysaccharides 3.9921114838
MESH:D008175 Lung Neoplasms arsenic trioxide 10.6911798837 19825857
MESH:D008175 Lung Neoplasms Curcumin 10.6919359593 16243823 18462866
MESH:D008175 Lung Neoplasms Dexamethasone 10.6915824018 11195469
MESH:D008175 Lung Neoplasms Plant Extracts 10.6920869020
MESH:D008175 Lung Neoplasms sodium arsenite 10.6915276417 17077188 16712894 19931552 17306315
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 10.6911884234 19555203
MESH:D008175 Lung Neoplasms Tobacco Smoke Pollution 10.6911091918 3440675 12111688 16288123
MESH:D008223 Lymphoma Curcumin 3.5718462866
MESH:D016399 Lymphoma, T-Cell Curcumin 4.6816173963
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.5411807958 17203775 11408345 16891317
MESH:D020149 Manganese Poisoning Estradiol 4.4819453300
MESH:D008545 Melanoma Curcumin 3.5018462866 17885582
MESH:D008545 Melanoma sodium arsenite 3.5016487513 19082730
MESH:D008569 Memory Disorders Curcumin 4.1417263510
MESH:D009062 Mouth Neoplasms Tobacco Smoke Pollution 4.3315006635
MESH:D009101 Multiple Myeloma arsenic trioxide 12.1219549372 15949261 11468182 14977855 19417148
MESH:D009101 Multiple Myeloma Curcumin 12.1219372569
MESH:D009101 Multiple Myeloma Dexamethasone 12.1216118317 15867202 15744524
MESH:D009134 Muscular Atrophy, Spinal Curcumin 4.9117962980
MESH:D009135 Muscular Diseases pirinixic acid 3.4916239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.6718349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 7.5216105982 16882451
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 7.529809623
MESH:D009203 Myocardial Infarction pirinixic acid 2.1319151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0012213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 8.1916810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 8.1916411023
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 10.2716624393
MESH:D009361 Neoplasm Invasiveness Curcumin 10.2718495463
MESH:D009362 Neoplasm Metastasis clopidogrel 4.1511875746
MESH:D009369 Neoplasms pirinixic acid 4.9117405874
MESH:D009369 Neoplasms sodium arsenite 4.9111559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.6520056578
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 4.5312497104
MESH:D009389 Neovascularization, Pathologic Estradiol 3.7217289903
MESH:D009421 Nervous System Malformations Estradiol 9.4111399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.4114600291
MESH:D009423 Nervous System Neoplasms Curcumin 5.6318462866
MESH:D009436 Neural Tube Defects arsenic trioxide 7.2910525206
MESH:D009436 Neural Tube Defects sodium arsenite 7.2912854658
MESH:D019954 Neurobehavioral Manifestations Plant Extracts 5.1717168769
MESH:D009765 Obesity Curcumin 7.5219297423
MESH:D009765 Obesity pirinixic acid 7.5220558911
MESH:D009765 Obesity Plant Extracts 7.5220132043 19056576
MESH:D010024 Osteoporosis Curcumin 3.4618719352
MESH:D010051 Ovarian Neoplasms arsenic trioxide 11.2612452020 19769630 16624393
MESH:D010051 Ovarian Neoplasms Curcumin 11.2618462866 19020741
MESH:D010051 Ovarian Neoplasms Estradiol 11.2619401270
MESH:D010051 Ovarian Neoplasms sodium arsenite 11.2617306315 15276417
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 5.4415580305
MESH:D010190 Pancreatic Neoplasms Curcumin 5.4419401701 17440100 19196508
MESH:D010195 Pancreatitis Trinitrobenzenesulfonic Acid 4.1817698068
MESH:D010212 Papilloma Plant Extracts 4.4815173996 16517061
MESH:D010235 Paraganglioma arsenic trioxide 4.1419927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.2512520081
MESH:D010538 Peritonitis Thioglycolates 5.7311985352 19804847 15707874 16751407 18628355 19641140 19180231
MESH:D011014 Pneumonia Lipopolysaccharides 4.5512224865 11605937
MESH:D017119 Porphyria Cutanea Tarda Hexachlorobenzene 11.059918132
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 11.0518163543
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.5321297632
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.1811399792 11118676 11222880 11896295
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.8720887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 1.8819131511
MESH:D011471 Prostatic Neoplasms Curcumin 1.8812497104 18226269 18156803 11398177 15129424 10851300 18769126
MESH:D011471 Prostatic Neoplasms Estradiol 1.8816740699
MESH:D011471 Prostatic Neoplasms Plant Extracts 1.8817804756 14666653
MESH:D011471 Prostatic Neoplasms sodium arsenite 1.8816039940
MESH:D011656 Pulmonary Emphysema Curcumin 4.5119168576
MESH:D015427 Reperfusion Injury pirinixic acid 2.3819058328
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 9.2518379247 10666014
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 9.2511700416 18379247
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.7210835634
MESH:D012135 Respiratory Sounds Tobacco Smoke Pollution 4.6118410779
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8218990726
MESH:D012170 Retinal Vein Occlusion clopidogrel 6.1119371211
MESH:D012509 Sarcoma Curcumin 4.1018462866
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.9416646077
MESH:D018805 Sepsis Curcumin 4.0618389075
MESH:D012878 Skin Neoplasms Plant Extracts 13.5716517061 15173996
MESH:D012878 Skin Neoplasms sodium arsenite 13.5719524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 13.5716192470
MESH:D012878 Skin Neoplasms Tobacco Smoke Pollution 13.5718590791
MESH:D016135 Spinal Dysraphism sodium arsenite 3.7812854658
MESH:D013272 Stomach Diseases Dexamethasone 4.3115472012
MESH:D013274 Stomach Neoplasms arsenic trioxide 1.8617007042
MESH:D013276 Stomach Ulcer Curcumin 12.1316631530 19188055
MESH:D013276 Stomach Ulcer Dexamethasone 12.1315138204
MESH:D013276 Stomach Ulcer Plant Extracts 12.1315255614 17135157 18237397 18193104 12787963
OMIM:265120 SURFACTANT METABOLISM DYSFUNCTION, PULMONARY, 1 marker/mechanism
MESH:D013705 Temporomandibular Joint Disorders Plant Extracts 13.2717997062
MESH:D013705 Temporomandibular Joint Disorders polyphenols 13.2717997062
MESH:D013921 Thrombocytopenia Lipopolysaccharides 4.1515821434
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.9012697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.0719014326
MESH:D013978 Tibial Fractures Estradiol 4.6919048282
MESH:D016171 Torsades de Pointes arsenic trioxide 3.9515213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 11.9520435036 12973940 12845720 11780464
MESH:D001749 Urinary Bladder Neoplasms Curcumin 11.9518593936
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 11.9511723127 17306315 16712894 16452187
MESH:D001749 Urinary Bladder Neoplasms Tobacco Smoke Pollution 11.9512846360
MESH:D014565 Urogenital Neoplasms Curcumin 5.2618462866
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 3.7511813266
MESH:D014605 Uveitis Dexamethasone 4.821336536
MESH:D014652 Vascular Diseases sodium arsenite 4.4217056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5912125929
MESH:D018487 Ventricular Dysfunction, Left Plant Extracts 4.7318097624
MESH:D020257 Ventricular Remodeling Plant Extracts 5.3118097624
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.2515886252
MESH:D014947 Wounds and Injuries Plant Extracts 4.2320213670 19894650
Pathway ID Pathway Name
KEGG:04210 Apoptosis
KEGG:04060 Cytokine-cytokine receptor interaction
KEGG:04630 Jak-STAT signaling pathway
REACT:6900 Signaling in Immune system
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA26939
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00020 agonist Sargramostim Antineoplastic Agents;Immunomodulatory Agents;Anti-Infective Agents
    DB02944 - Alpha-D-Mannose
    DB03965 - Fucose
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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