AutismKB 2.0

Annotation Detail for SPTY2D1


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Basic Information Top
Gene Symbol:SPTY2D1 ( DKFZp686F1942,DKFZp686I068,FLJ39441 )
Gene Full Name: SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
Band: 11p15.1
Quick LinksEntrez ID:144108; OMIM: NA; Uniprot ID:SPT2_HUMAN; ENSEMBL ID: ENSG00000179119; HGNC ID: 26818
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of SPTY2D1 mRNAaffects expression 17562736
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of SPTY2D1 mRNAdecreases expression 20018196
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.9110982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.8310977129
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 3.0420889678
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6811834606 12153990 16109766 19164858 15968718 19416960 12958197 19739265 16081117 14550746 19420014 12594235 19923254 11739529 19085960 11529661 11421492 16781746 16485898 11743745 12705907 18713872 17522070 10663392 10774834 12540782 17906064 11461765 15619225 19370779 11287661 14986274 18071297 16177239 16393943 17562736 12392966 10915739 14725611 16227642 2444490
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.1719426721
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1620426865
MESH:D005756 Gastritis Acetaminophen 4.7416983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1116870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4415629191 12587719
MESH:D008107 Liver Diseases Acetaminophen 1.7116610002 19460945 19014921 16611625 11587558 19784758 12587719 12969438
MESH:D017114 Liver Failure, Acute Acetaminophen 3.7416871587 17185352
MESH:D008546 Melanoma, Experimental Acetaminophen 4.3319513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3118514411
MESH:D010146 Pain Acetaminophen 2.8216870215
MESH:D014581 Urticaria Acetaminophen 3.5810982225
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018