AutismKB 2.0

Annotation Detail for SLC2A14


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Basic Information Top
Gene Symbol:SLC2A14 ( DKFZp564K1672,GLUT14,SLC2A3P3 )
Gene Full Name: solute carrier family 2 (facilitated glucose transporter), member 14
Band: 12p13.31
Quick LinksEntrez ID:144195; OMIM: 611039; Uniprot ID:GTR14_HUMAN; ENSEMBL ID: ENSG00000173262; HGNC ID: 18301
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D003035 Cobalt [tungsten carbide binds to Cobalt] which results in increased expression of SLC2A14 mRNAaffects binding|increases expression 20105288
C018021 cobaltous chloride cobaltous chloride results in increased expression of SLC2A14 mRNAincreases expression 20105288
D005472 Fluorouracil SLC2A14 protein affects the susceptibility to Fluorouracilaffects response to substance 16217747
C056507 gemcitabine gemcitabine results in increased expression of SLC2A14 mRNAincreases expression 17039268
D007501 Iron Iron deficiency results in increased expression of SLC2A14 mRNAincreases expression 20368581
C452423 N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine results in increased expression of SLC2A14 mRNAincreases expression 16052530
C004648 testosterone enanthate testosterone enanthate affects the expression of SLC2A14 mRNAaffects expression 17440010
C002802 tungsten carbide [tungsten carbide binds to Cobalt] which results in increased expression of SLC2A14 mRNAaffects binding|increases expression 20105288
D014807 Vitamin D Vitamin D affects the expression of SLC2A14 mRNAaffects expression 20368581
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Fluorouracil 2.4717638652
MESH:D019896 alpha 1-Antitrypsin Deficiency Iron 5.9416640825
MESH:D000544 Alzheimer Disease Iron 3.0416563566 16640825
MESH:D000740 Anemia Fluorouracil 9.8615504547 17963324 16511603
MESH:D000740 Anemia Iron 9.8616566752 16434484
MESH:D018798 Anemia, Iron-Deficiency Iron 4.8417163184 16569441 17162259 17147795 17375513
MESH:D000756 Anemia, Sideroblastic Iron 5.0216910769
MESH:D001145 Arrhythmias, Cardiac Iron 4.5616604332
MESH:D001260 Ataxia Telangiectasia Iron 5.7315336622
MESH:D050197 Atherosclerosis Iron 3.8216632123 16640825
MESH:D001321 Autistic Disorder Iron 2.7817352947
MESH:D001424 Bacterial Infections Iron 5.4816640825
MESH:D001943 Breast Neoplasms Cobalt 2.2815986119
MESH:D001943 Breast Neoplasms Fluorouracil 2.2818357371 16110121 15136595 16595493 16557594 19217205 18608205
MESH:D001943 Breast Neoplasms gemcitabine 2.2818382427 17039268
MESH:D002276 Carcinoid Tumor Fluorouracil 4.9916051944
MESH:D002277 Carcinoma Fluorouracil 3.7317121937
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 2.1117088986 17971768 17045692 18930000 16799960 16332177
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 3.1018695887
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 2.5418986760 16280240 16757204 17066447
MESH:D009202 Cardiomyopathies Iron 4.1716640825
MESH:D002311 Cardiomyopathy, Dilated Iron 3.5216604332
MESH:D003110 Colonic Neoplasms Fluorouracil 4.1817172411 17725105 17018589 15001691 16340194 18772588 17169374 16510598 17016597 17287894
MESH:D003110 Colonic Neoplasms Iron 4.1816640825
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.0018448328 17401013 17016601 17695437 18509181 16391804 17094418 20501625 15289873 16331619 17454858 18802399 18949393 16524972 17594712 15148649 18383874 16282729 17255274 14970324 18288408 16303861
MESH:D007644 Darier Disease Fluorouracil 5.0816733453
MESH:D017449 Dermatitis, Allergic Contact cobaltous chloride 4.2815059100 11298694 16823706
MESH:D003920 Diabetes Mellitus Iron 4.6316640825 16604332
MESH:D003922 Diabetes Mellitus, Type 1 Iron 3.4116506275
MESH:D003924 Diabetes Mellitus, Type 2 Iron 3.1316506275
MESH:D004938 Esophageal Neoplasms Fluorouracil 2.4917638652 16481741 16337965 16785472 15173087
MESH:D005234 Fatty Liver Iron 4.2916640825
MESH:D005621 Friedreich Ataxia Iron 5.6916640825 16604332
MESH:D005910 Glioma Fluorouracil 2.9416145905
MESH:D006258 Head and Neck Neoplasms Fluorouracil 3.5215102660 15162350 18337622
MESH:D006432 Hemochromatosis Iron 4.6316574947 16640825 17236123 16604332 17255318 17053826
MESH:D006486 Hemosiderosis Iron 5.5316604332
MESH:D006525 Hepatitis, Viral, Human Iron 5.7916640825
MESH:D006527 Hepatolenticular Degeneration Iron 5.2017182432
MESH:D006529 Hepatomegaly Iron 4.5716890145
MESH:D015658 HIV Infections Iron 3.7716597321
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 6.0617440010
MESH:D006973 Hypertension Cobalt 3.9717039479
MESH:D007006 Hypogonadism Iron 4.5416640825
MESH:D007037 Hypothyroidism Iron 5.3416640825
MESH:D019189 Iron Metabolism Disorders Iron 5.2617163184
MESH:D007680 Kidney Neoplasms Fluorouracil 3.4816985049
MESH:D015470 Leukemia, Myeloid, Acute Vitamin D 3.8220368581
MESH:D020961 Lewy Body Disease Iron 5.6916563566
MESH:D008103 Liver Cirrhosis Iron 3.8316640825
MESH:D008108 Liver Diseases, Alcoholic Iron 5.2617207112 16737972
MESH:D008113 Liver Neoplasms Fluorouracil 5.2417045692 16603448 18383874 15113037
MESH:D008113 Liver Neoplasms Iron 5.2416640825 20302851
MESH:D008173 Lung Diseases, Obstructive Cobalt 6.126434250
MESH:D008175 Lung Neoplasms Fluorouracil 2.9215246190
MESH:D008175 Lung Neoplasms Iron 2.9216640825
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 5.0815086387
MESH:D008268 Macular Degeneration Iron 4.0816640825
MESH:D009062 Mouth Neoplasms Fluorouracil 3.7916757204 18986760
MESH:D020528 Multiple Sclerosis, Chronic Progressive Iron 5.9917086897
MESH:D009181 Mycoses Iron 5.7916640825
MESH:D017202 Myocardial Ischemia Iron 4.6116604332
MESH:D015428 Myocardial Reperfusion Injury Iron 4.4216604332
MESH:D009369 Neoplasms Fluorouracil 2.7018239605 18600527 16928823
MESH:D009404 Nephrotic Syndrome Iron 4.7017178036
MESH:D019636 Neurodegenerative Diseases Iron 4.4117296847 16604332
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.5716436463
MESH:D010003 Osteoarthritis Iron 4.0816640825
MESH:D010024 Osteoporosis Iron 8.4416640825 16648989
MESH:D010024 Osteoporosis Vitamin D 8.4417882678
MESH:D010190 Pancreatic Neoplasms Fluorouracil 5.9515113037 16929163 16500647 19003803
MESH:D010190 Pancreatic Neoplasms gemcitabine 5.9511504793 16929163 18383843 18992248 17440100
MESH:D010212 Papilloma Iron 4.7412065085
MESH:D020447 Parasomnias Iron 6.3417352947
MESH:D010300 Parkinson Disease Iron 3.3816640825 16563566
MESH:D010900 Pituitary Diseases Iron 5.9916604332
MESH:D011041 Poisoning Iron 4.5116604332
MESH:D017119 Porphyria Cutanea Tarda Iron 5.2216640825
MESH:D011225 Pre-Eclampsia Iron 4.5816640825
MESH:D011471 Prostatic Neoplasms Fluorouracil 3.3819082440 18626508
MESH:D011528 Protozoan Infections Iron 6.3416640825
MESH:D011658 Pulmonary Fibrosis Cobalt 4.066434250
MESH:D012004 Rectal Neoplasms Fluorouracil 4.1918722050 18286688 15538739 16160472
MESH:D012148 Restless Legs Syndrome Iron 4.7016930377
MESH:D012878 Skin Neoplasms Iron 3.5512065085
MESH:D013274 Stomach Neoplasms Fluorouracil 2.0017172411 18396642 17522103 16424979 16951190 19015929 19084572 17498489 15786421 18567086
MESH:D013398 Sudden Infant Death Iron 5.7316640825
MESH:D013964 Thyroid Neoplasms N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine 5.0016940797
MESH:D014062 Tongue Neoplasms Fluorouracil 4.1816280240
MESH:D014376 Tuberculosis Iron 4.2016597321
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 4.0716803524
Pathway ID Pathway Name
KEGG:04920 Adipocytokine signaling pathway
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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