AutismKB 2.0

Annotation Detail for FBXL14


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Basic Information Top
Gene Symbol:FBXL14 ( Fbl14,MGC40195 )
Gene Full Name: F-box and leucine-rich repeat protein 14
Band: 12p13.33
Quick LinksEntrez ID:144699; OMIM: 609081; Uniprot ID:FXL14_HUMAN; ENSEMBL ID: ENSG00000171823; HGNC ID: 28624
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of FBXL14 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of FBXL14 mRNAaffects expression 16483693
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.4418287403
MESH:D000799 Angioedema Acetaminophen 4.9110982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.8310977129
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6814550746 10663392 12540782 19370779 11529661 11739529 10915739 19420014 11287661 12153990 19739265 11743745 11421492 16393943 19416960 10774834 16227642 16485898 16781746 12594235 14725611 19164858 18071297 12392966 15968718 15619225 16177239 18713872 19085960 2444490 11461765 17562736 16109766 19923254 14986274 11834606 12705907 12958197 17906064 16081117 17522070
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.1719426721
MESH:D005756 Gastritis Acetaminophen 4.7416983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1116870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4412587719 15629191
MESH:D008107 Liver Diseases Acetaminophen 1.7111587558 19460945 16611625 19784758 12587719 12969438 16610002 19014921
MESH:D017114 Liver Failure, Acute Acetaminophen 3.7416871587 17185352
MESH:D008546 Melanoma, Experimental Acetaminophen 4.3319513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3118514411
MESH:D010146 Pain Acetaminophen 2.8216870215
MESH:D014581 Urticaria Acetaminophen 3.5810982225
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018