AutismKB 2.0

Annotation Detail for CSNK1E


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Basic Information Top
Gene Symbol:CSNK1E ( HCKIE,MGC10398 )
Gene Full Name: casein kinase 1, epsilon
Band: 22q13.1
Quick LinksEntrez ID:1454; OMIM: 600863; Uniprot ID:KC1E_HUMAN; ENSEMBL ID: ENSG00000213923; HGNC ID: 2453
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04710Circadian rhythm - mammal
hsa04310Wnt signaling pathway
hsa04340Hedgehog signaling pathway
Pathway IDPathway Name
Cell Cycle, Mitotic
Pathway IDPathway Name
200068Circadian rhythm pathway
200091FoxO family signaling
200175p53 pathway
200147Hedgehog signaling events mediated by Gli proteins
Pathway IDPathway Name
P00015Circadian clock system
P00025Hedgehog signaling pathway
P00049Parkinson disease
P00057Wnt signaling pathway
Pathway IDPathway Name
500383Loss of proteins required for interphase microtubule organization from the centrosome
500384Loss of Nlp from mitotic centrosomes
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1848Embryoma
1841Stomach cancer
Desease Name
NORMALVARIATION
sleep disorders
D-amphetamine response
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of CSNK1E mRNAaffects expression 21346803
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of CSNK1E mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of CSNK1E mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CSNK1E mRNAaffects expression 16483693
D000661 Amphetamine CSNK1E gene polymorphism affects the susceptibility to Amphetamineaffects response to substance 16237383
D000661 Amphetamine CSNK1E protein results in increased susceptibility to Amphetamineincreases response to substance 16237383
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of CSNK1E mRNAdecreases expression 19150397
C006780 bisphenol A bisphenol A results in decreased expression of CSNK1E mRNAdecreases expression 20678512
C005961 bis(tri-n-butyltin)oxide bis(tri-n-butyltin)oxide results in increased expression of CSNK1E mRNAincreases expression 17553608
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of CSNK1E mRNAdecreases expression 17484886
D004041 Dietary Fats Dietary Fats results in increased expression of CSNK1E mRNAincreases expression 18042831
D005472 Fluorouracil Fluorouracil affects the expression of CSNK1E mRNAaffects expression 16584549
C411652 IC 261 IC 261 results in increased expression of CSNK1E proteinincreases expression 16027726
C041786 palm oil palm oil results in increased expression of CSNK1E mRNAincreases expression 18042831
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of CSNK1E mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of CSNK1E mRNAincreases expression 19482888
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of CSNK1E mRNAaffects binding|decreases expression|increases activity 19710929
D012643 Selenium [Selenium co-treated with Vitamin E] results in decreased expression of CSNK1E mRNAaffects cotreatment|decreases expression 19244175
D012643 Selenium Selenium results in increased expression of CSNK1E mRNAincreases expression 19244175
D018038 Sodium Selenite Sodium Selenite results in increased expression of CSNK1E mRNAincreases expression 18175754
D013974 Thyroxine Thyroxine affects the expression of CSNK1E mRNAaffects expression 17403546
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of CSNK1E mRNAincreases expression 18495758
D014810 Vitamin E [Selenium co-treated with Vitamin E] results in decreased expression of CSNK1E mRNAaffects cotreatment|decreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 13.777525203
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 13.776195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 13.7714514962 15322242 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.4718287403
MESH:D055371 Acute Lung Injury pirinixic acid 3.0318653653
MESH:D000230 Adenocarcinoma Fluorouracil 2.4117638652
MESH:D018248 Adenoma, Liver Cell Phenobarbital 16.8017620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 16.8016434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 16.8016835633
MESH:D019969 Amphetamine-Related Disorders Amphetamine 5.9715010207 16459022 16916582 18475255
MESH:D000740 Anemia Fluorouracil 8.4215504547 17963324 16511603
MESH:D000740 Anemia Tetrachlorodibenzodioxin 8.4211748828
MESH:D000799 Angioedema Acetaminophen 3.7610982225
MESH:D000855 Anorexia Amphetamine 4.9316084549 12005258 16101753 12183048
MESH:D001161 Arteriosclerosis Dietary Fats 3.8015238619
MESH:D001321 Autistic Disorder Acetaminophen 1.4318445737
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.4919483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.4912125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7115746008
MESH:D001862 Bone Resorption bisphenol A 3.7811985600
MESH:D001943 Breast Neoplasms bisphenol A 1.9417123778
MESH:D001943 Breast Neoplasms Dietary Fats 1.9420435547
MESH:D001943 Breast Neoplasms Fluorouracil 1.9418357371 15136595 18608205 16595493 16557594 19217205 16110121
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9420435547
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 9.6415673190 16097048 15721981 16192424 10355542 16050911 16227642 16011737 15700767 16124888 3786805 18705752
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 9.6416050911
MESH:D002276 Carcinoid Tumor Fluorouracil 4.5916051944
MESH:D002277 Carcinoma Fluorouracil 7.9517121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.9516835633
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 8.7216705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 8.723084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 8.7218788625
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 8.7216332177 16799960 17045692 17971768 18930000 17088986
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 8.721701930 6705139 20007298 17173139 20935162
MESH:D002278 Carcinoma in Situ bisphenol A 4.9017123778
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 2.9818695887
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 2.4716757204 16280240 18986760 17066447
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.9316120746 18670907 18850075
MESH:D006332 Cardiomegaly Thyroxine 6.9318093424
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 7.2514694615
MESH:D002386 Cataract Acetaminophen 7.2510977129
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.6620889678
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.164080065
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.0816835633
MESH:D002779 Cholestasis pirinixic acid 2.7619176532
MESH:D019457 Chromosome Breakage Sodium Selenite 4.6615894690
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0712621046 15340226 16354765 8697196 15668235
MESH:D003092 Colitis Selenium 3.6917936198
MESH:D003110 Colonic Neoplasms Fluorouracil 2.2216510598 17725105 15001691 17169374 18772588 17018589 16340194 17016597 17287894 17172411
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.0017016601 16524972 15289873 17695437 17594712 20501625 16282729 18802399 18383874 16391804 16331619 14970324 18509181 17255274 15148649 18448328 16303861 18949393 17401013 18288408 17454858 17094418
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 8.9315095906
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 8.9314669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4515322242 20055451 10048152
MESH:D019465 Craniofacial Abnormalities Vitamin E 2.4519769572
MESH:D003490 Cyanosis 2,4-dinitrotoluene 3.9318551238
MESH:D007644 Darier Disease Fluorouracil 4.7116733453
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3818249437
MESH:D003920 Diabetes Mellitus Sodium Selenite 3.7016285004
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6517107852
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 18.3018551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 18.3021346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 18.3012958197 16781746 14986274 19739265 11287661 11529661 16081117 14725611 11834606 10663392 16227642 12540782 18071297 12153990 11461765 14550746 19416960 18713872 12705907 16393943 17522070 17562736 11421492 12594235 17906064 11739529 10915739 10774834 12392966 11743745 19420014 16485898 16177239 16109766 19164858 19923254 19085960 15619225 2444490 19370779 15968718
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 18.3021278145 7179309 16227642 6884620 10915739 10092053 16177239 6623471 7440962 11566570 19085960 15027814 2869522 19336974 7120509 15968718 17522070 15998439 3732212 9327722 3786805 4309450
MESH:D056486 Drug-Induced Liver Injury Selenium 18.3015131321
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 18.3015131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 18.3020420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.0219426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6911462148
MESH:D050171 Dyslipidemias Dietary Fats 3.3918367378
MESH:D004421 Dystonia Phenobarbital 3.921851702
MESH:C538011 Eales disease Vitamin E 4.629068938
MESH:D004487 Edema pirinixic acid 6.2712083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.2712711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.8215322242 18230668 16714409
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.9410568697 9294722
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.023659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.793922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.8420417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.466401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.167750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.933659116
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.4420426865
MESH:D004938 Esophageal Neoplasms Fluorouracil 4.4417638652 15173087 16785472 16337965 16481741
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9511564622
MESH:D005221 Fatigue Amphetamine 5.5119890266
MESH:D005234 Fatty Liver Carbon Tetrachloride 12.6261145 15959796 16239168 12795759 16045604 12631006 19224547 17595544
MESH:D005234 Fatty Liver Dietary Fats 12.6219551842 19004024 18296743 17967931
MESH:D005234 Fatty Liver pirinixic acid 12.6220131406 19236843
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3711858732
MESH:D005355 Fibrosis Carbon Tetrachloride 14.2618705752
MESH:D005355 Fibrosis Dietary Fats 14.2618296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 14.2620067830
MESH:D005756 Gastritis Acetaminophen 3.5916983495
MESH:D005910 Glioma Fluorouracil 2.8316145905
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5110696789
MESH:D006258 Head and Neck Neoplasms Fluorouracil 3.3318337622 15162350 15102660
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.4210048152 11294989
MESH:D006330 Heart Defects, Congenital Vitamin E 6.4216080930
MESH:D006333 Heart Failure pirinixic acid 6.7720558911
MESH:D006333 Heart Failure Selenium 6.7717162251
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2511000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.5119900420 19110552
MESH:D006529 Hepatomegaly Phenobarbital 13.8816109766
MESH:D006529 Hepatomegaly pirinixic acid 13.8818467677 16221962 19772884 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 13.8812621046 15340226 16120746
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.6716863852 16490937
MESH:D019584 Hot Flashes Vitamin E 3.8914716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.9616354765 18606429 16959395 15340226 8697196
MESH:D006930 Hyperalgesia Acetaminophen 2.6316870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.4516899240
MESH:D006937 Hypercholesterolemia Dietary Fats 3.5121332399
MESH:D006943 Hyperglycemia pirinixic acid 3.1020558911
MESH:D006948 Hyperkinesis Amphetamine 5.3514960337 1977408
MESH:D006949 Hyperlipidemias Dietary Fats 3.5321332399
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.8718850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.0015338365
MESH:D007249 Inflammation Dietary Fats 4.7620412841
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.7612200463 12878042
MESH:D007251 Influenza, Human Selenium 10.6916624496
MESH:D007251 Influenza, Human Vitamin E 10.6916624496
MESH:D007333 Insulin Resistance bisphenol A 17.1816393666
MESH:D007333 Insulin Resistance Dietary Fats 17.1811836018 18457598
MESH:D007333 Insulin Resistance pirinixic acid 17.1816306350
MESH:D007333 Insulin Resistance Sodium Selenite 17.1814714311
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2516580747
MESH:D007674 Kidney Diseases Acetaminophen 5.8015629191 12587719
MESH:D007674 Kidney Diseases Vitamin E 5.8012488133
MESH:D007676 Kidney Failure, Chronic Selenium 3.8016518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 7.2416705839
MESH:D007680 Kidney Neoplasms Fluorouracil 7.2416985049
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 10.7517174718 16943688 17157831 11408273 21278145 16221502 17334410 16239168 11903743
MESH:D008103 Liver Cirrhosis Dietary Fats 10.7518296743
MESH:D008103 Liver Cirrhosis Phenobarbital 10.7521047994
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 4.8417481882 16027843 18054572 17565644 15730626 18705752 17557913 14716833 15673190 18263696 17805973 18429990 16015684 15959796 15893842 15362042 12632514 18156304 12445418 17976157 18166357 17525996 18395914 16011737 12389079 12667390 16136751 18339082 12898905 18420326 15370692 18418968 16638106 15057751 12649538 18205269 15338365 16116963 18472332 12609069 14724832 18395095 14620537 17944888 18210741 18317297 14716496 15876570 15650968 12586293 18412020 17640975 17823541 12445421 16248980 16097048 18006644 17900296 14748882 15123356 17922224 18481824 15931870 18279442 11481614 16033810 15925388 10355542 12666154 17721639 20821823 12741479 14512876 15052691 18277467 15996030 17698563 18251166 18472094 17766677 17869086 12632512 12546737 12958196 16192424 17708605 17631135 18187930 17714472 18376398 13678700 17761835 15818738
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.8415474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.8412878042
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 4.8416169303
MESH:D008107 Liver Diseases Acetaminophen 6.3519460945 16611625 12969438 16610002 19014921 11587558 19784758 12587719
MESH:D008107 Liver Diseases Carbon Tetrachloride 6.3516246199 15830285 17285989 16964402 15720792
MESH:D008107 Liver Diseases Phenobarbital 6.3519363144
MESH:D017093 Liver Failure Carbon Tetrachloride 4.0815123358
MESH:D017114 Liver Failure, Acute Acetaminophen 9.1417185352 16871587
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 9.1416899240 14706259
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 13.8819294768
MESH:D008113 Liver Neoplasms Fluorouracil 13.8815113037 17045692 16603448 18383874
MESH:D008113 Liver Neoplasms Phenobarbital 13.8819482888 19073162 8742319 15975961 21047994 19812893
MESH:D008113 Liver Neoplasms pirinixic acid 13.8815890375 16377806 20007298
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 13.8816984957
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 9.4812014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 9.481399818 2563599 18308698 6150874 17172636
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 9.4812151625
MESH:D008171 Lung Diseases Vitamin E 3.1216863852
MESH:D008175 Lung Neoplasms Fluorouracil 3.3715246190
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.3711884234 19555203
MESH:D008175 Lung Neoplasms Vitamin E 3.3711062179
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.7115086387
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 3.9714737004
MESH:D008325 Mammary Neoplasms, Experimental Selenium 2.7115318939
MESH:D008546 Melanoma, Experimental Acetaminophen 3.4819513568
MESH:D008654 Mesothelioma Selenium 2.7615107826
MESH:D009062 Mouth Neoplasms Fluorouracil 3.5616757204 18986760
MESH:D009135 Muscular Diseases pirinixic acid 3.4216239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.1119151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9512213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.8816411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.3917484760
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.7718551238
MESH:D009369 Neoplasms Fluorouracil 4.8418600527 16928823 18239605
MESH:D009369 Neoplasms pirinixic acid 4.8417405874
MESH:D009421 Nervous System Malformations bisphenol A 9.3016427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.3014600291
MESH:D019636 Neurodegenerative Diseases Acetaminophen 8.4118514411
MESH:D019636 Neurodegenerative Diseases Amphetamine 8.4115183010
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.3816436463
MESH:D009765 Obesity Dietary Fats 4.3621332399 16723640 19632207 18457598 18674790 20132043 17217161 11836018 20518802
MESH:D009765 Obesity pirinixic acid 4.3620558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 8.8716049721 12819281
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 8.8714694615
MESH:D010018 Osteomalacia Phenobarbital 4.2817016548
MESH:D010049 Ovarian Diseases bisphenol A 4.9011985600
MESH:D010146 Pain Acetaminophen 2.3216870215
MESH:D010190 Pancreatic Neoplasms Fluorouracil 5.2515113037 19003803 16500647 16929163
MESH:D010190 Pancreatic Neoplasms Phenobarbital 5.2516965848
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1712520081
MESH:D010954 Plasmacytoma Selenium 4.8115087411
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4718163543
MESH:D011230 Precancerous Conditions Phenobarbital 3.552563599
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 9.2210548101
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 9.2211399792 11896295 11222880 11118676
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 4.1220887781
MESH:D011471 Prostatic Neoplasms bisphenol A 2.1216740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 2.1218626508 19082440
MESH:D011471 Prostatic Neoplasms Sodium Selenite 2.1218760546
MESH:D011471 Prostatic Neoplasms Vitamin E 2.1215084515
MESH:D019310 Pseudolymphoma Phenobarbital 4.4112752131
MESH:D011629 Puberty, Precocious bisphenol A 4.7010548101
MESH:D012004 Rectal Neoplasms Fluorouracil 3.9316160472 15538739 18722050 18286688
MESH:D015427 Reperfusion Injury pirinixic acid 2.3419058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7518990726
MESH:D012640 Seizures 2,4-dinitrotoluene 5.7218551238
MESH:D012640 Seizures Phenobarbital 5.7216876388 11442880 3137016 4039156
MESH:D003294 Seizures, Febrile Phenobarbital 4.746407741
MESH:D012871 Skin Diseases Vitamin E 2.4218709164
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.0016192470
MESH:D019956 Stereotypic Movement Disorder Amphetamine 6.341977408
MESH:D013274 Stomach Neoplasms Fluorouracil 2.0018567086 19015929 15786421 17498489 17522103 16951190 18396642 17172411 16424979 19084572
MESH:D020521 Stroke Vitamin E 3.4516517955
MESH:D019966 Substance-Related Disorders bisphenol A 3.9016684133 16045194
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 12.1012697716
MESH:D013959 Thyroid Diseases Thyroxine 12.1019910387
MESH:D013964 Thyroid Neoplasms Phenobarbital 2.991399818
MESH:D014062 Tongue Neoplasms Fluorouracil 3.9116280240
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 2.2516049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.2310091137
MESH:D014581 Urticaria Acetaminophen 2.8910982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 3.8016803524
MESH:D014591 Uterine Diseases bisphenol A 4.9314652134
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5112125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1715886252
MESH:D015430 Weight Gain Dietary Fats 3.6616723640
Pathway ID Pathway Name
REACT:152 Cell Cycle, Mitotic
REACT:24941 Circadian Clock
REACT:24972 Circadian Clock (mouse)
KEGG:04711 Circadian rhythm - fly
KEGG:04710 Circadian rhythm - mammal
KEGG:04340 Hedgehog signaling pathway
KEGG:04310 Wnt signaling pathway
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA26953
    • No data
    Releated disease ID Related disease Name
    PA443560Breast Neoplasms
    No data
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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