AutismKB 2.0

Annotation Detail for FAM81A


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Basic Information Top
Gene Symbol:FAM81A ( MGC26690 )
Gene Full Name: family with sequence similarity 81, member A
Band: 15q22.2
Quick LinksEntrez ID:145773; OMIM: NA; Uniprot ID:FA81A_HUMAN; ENSEMBL ID: ENSG00000157470; HGNC ID: 28379
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
D000638 Amiodarone Amiodarone results in increased expression of FAM81A mRNAincreases expression 19774075
D016047 Zalcitabine [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of FAM81A mRNAaffects cotreatment|decreases expression 18606552
C514793 gp120 protein, Human immunodeficiency virus 1 [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of FAM81A mRNAaffects cotreatment|decreases expression 18606552
D010634 Phenobarbital Phenobarbital results in decreased expression of FAM81A mRNAdecreases expression 19270015
C025643 vinclozolin vinclozolin affects the expression of FAM81A mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 3.986195326
MESH:D018248 Adenoma, Liver Cell Phenobarbital 4.5117620307
MESH:D001008 Anxiety Disorders vinclozolin 3.9319015723
MESH:D001145 Arrhythmias, Cardiac Amiodarone 4.1520041841 18057881 18218290
MESH:D001281 Atrial Fibrillation Amiodarone 4.1618651412 19698954
MESH:D001778 Blood Coagulation Disorders Amiodarone 4.2719483382
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 1.9417173139 1701930 20935162 20007298 6705139
MESH:D009202 Cardiomyopathies Zalcitabine 4.9210591146
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.9915710769 19225199
MESH:D002341 Carotid Artery Thrombosis Amiodarone 5.6218974383
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.744080065
MESH:D003456 Cryptorchidism vinclozolin 4.7814966744
MESH:D056486 Drug-Induced Liver Injury Amiodarone 2.4615265979 18218290
MESH:D004362 Drug Toxicity Zalcitabine 5.117515130
MESH:D004421 Dystonia Phenobarbital 4.411851702
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.593659116
MESH:D004828 Epilepsies, Partial Phenobarbital 4.483922381 11558140
MESH:D004827 Epilepsy Phenobarbital 3.0420417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.876401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.747750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 4.563659116
MESH:D005234 Fatty Liver Amiodarone 9.8014986274
MESH:D005234 Fatty Liver Zalcitabine 9.8018299183
MESH:D030342 Genetic Diseases, Inborn vinclozolin 5.4716973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.9116417039
MESH:D006529 Hepatomegaly Amiodarone 10.4215265979
MESH:D006529 Hepatomegaly Phenobarbital 10.4216109766
MESH:D015658 HIV Infections Zalcitabine 4.4917457083
MESH:D006937 Hypercholesterolemia Amiodarone 4.259751232 8137927
MESH:D007037 Hypothyroidism Amiodarone 5.0017991464 18020914
MESH:D007248 Infertility, Male vinclozolin 3.2616467254
MESH:D007984 Leydig Cell Tumor vinclozolin 5.2716417039
MESH:D008064 Lipidoses Amiodarone 3.7617567588 15342952
MESH:D008103 Liver Cirrhosis Phenobarbital 3.0721047994
MESH:D008107 Liver Diseases Phenobarbital 2.2319363144
MESH:D008113 Liver Neoplasms Phenobarbital 2.4119812893 8742319 19073162 19482888 15975961 21047994
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 2.9018308698 1399818 17172636 6150874 2563599
MESH:D008133 Long QT Syndrome Amiodarone 3.8517391786 11989578 15350150
MESH:D008171 Lung Diseases Amiodarone 3.6012587719
MESH:D017563 Lung Diseases, Interstitial Amiodarone 5.0918516814
MESH:D008223 Lymphoma Zalcitabine 4.8817941976 8840982 18798262 8764131 9488045 9205081 11980663
MESH:D009181 Mycoses Amiodarone 5.5112754197 17974566
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 5.0217484760
MESH:D009374 Neoplasms, Experimental Zalcitabine 5.589205081 9488045 8764131
MESH:D009437 Neuralgia Zalcitabine 6.8617292584
MESH:D010018 Osteomalacia Phenobarbital 4.9017016548
MESH:D010190 Pancreatic Neoplasms Phenobarbital 2.5916965848
MESH:D010523 Peripheral Nervous System Diseases gp120 protein, Human immunodeficiency virus 1 12.4418606552
MESH:D010523 Peripheral Nervous System Diseases Zalcitabine 12.4418606552
MESH:D011230 Precancerous Conditions Phenobarbital 3.952563599
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 4.4418220299 18042343 19015723
MESH:D011469 Prostatic Diseases vinclozolin 5.4718220299
MESH:D011472 Prostatitis vinclozolin 5.4718629315
MESH:D019310 Pseudolymphoma Phenobarbital 5.1112752131
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.9612490602 12832656 11597910
MESH:D012640 Seizures Phenobarbital 2.9216876388 3137016 11442880 4039156
MESH:D003294 Seizures, Febrile Phenobarbital 5.366407741
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 5.6218724381
MESH:D013276 Stomach Ulcer Amiodarone 3.6818087811
MESH:D013610 Tachycardia Amiodarone 4.7311238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.6319225199
MESH:D013959 Thyroid Diseases Amiodarone 5.3719731979
MESH:D013964 Thyroid Neoplasms Phenobarbital 3.321399818
MESH:D013971 Thyrotoxicosis Amiodarone 5.3418020914 19584973
MESH:D016171 Torsades de Pointes Amiodarone 4.7311989578 17467628
No data
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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