AutismKB 2.0

Annotation Detail for VCAN


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:VCAN ( CSPG2,DKFZp686K06110,ERVR,GHAP,PG-M,WGN,WGN1 )
Gene Full Name: versican
Band: 5q14.2-q14.3
Quick LinksEntrez ID:1462; OMIM: 118661; Uniprot ID:CSPG2_HUMAN; ENSEMBL ID: ENSG00000038427; HGNC ID: 2464
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04514Cell adhesion molecules (CAMs)
No data
Pathway IDPathway Name
200106Regulation of Wnt-mediated beta catenin signaling and target gene transcription
200177Endogenous TLR signaling
200101Direct p53 effectors
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1770Melanoma
1801Intracranial aneurysm
1831Prostate cancer
1843Metastasis to lymph nodes
1850Herpes
1860Brain tumor
1944Breast cancer
1961Endometrium cancer
1986Eating disorder
2044Pre-Eclampsia
2076Spondylarthropathies
2122Protein-energy malnutrition
1855Prostatic hypertrophy, Benign
No data
Desease Name
Major depressive disorder
Desease Name
Wagner syndrome 1
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of VCAN mRNAincreases expression 19933214
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of VCAN proteinaffects expression 20106945
D016589 Astemizole Astemizole results in decreased expression of VCAN mRNAdecreases expression 20221588
D001564 Benzo(a)pyrene Benzo(a)pyrene affects the expression of VCAN mRNAaffects expression 20106945
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of VCAN mRNAdecreases expression 15336504
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of VCAN mRNAaffects expression 12734012
D003345 Corticosterone Corticosterone results in decreased expression of VCAN mRNAdecreases expression 15755911
D003474 Curcumin Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAN mRNA]decreases reaction|increases expression 18200517
D003907 Dexamethasone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of VCAN mRNAaffects cotreatment|increases expression 16054899
D005047 Etoposide VCAN protein affects the susceptibility to Etoposideaffects response to substance 16217747
D006820 Hyaluronic Acid VCAN protein binds to and results in increased stability of Hyaluronic Acidaffects binding|increases stability 15836955
D015056 1-Methyl-3-isobutylxanthine [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of VCAN mRNAaffects cotreatment|increases expression 16054899
C000873 methylprednisolone acetate methylprednisolone acetate results in decreased expression of VCAN mRNAdecreases expression 15693093
D008942 Mitoxantrone VCAN protein affects the susceptibility to Mitoxantroneaffects response to substance 16217747
D010656 Phenylephrine Phenylephrine results in increased expression of VCAN mRNAincreases expression 18158353
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of VCAN mRNAaffects binding|decreases expression|increases activity 19710929
C116926 rofecoxib rofecoxib results in decreased expression of VCAN mRNAdecreases expression 17070997
C089730 rosiglitazone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of VCAN mRNAaffects cotreatment|increases expression 16054899
C017947 sodium arsenite sodium arsenite results in increased expression of VCAN mRNAincreases expression 20308225
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of VCAN mRNAdecreases expression 20106945
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin affects the expression of VCAN mRNAaffects expression 18691609
D019772 Topotecan VCAN protein affects the susceptibility to Topotecanaffects response to substance 16217747
D014302 Trinitrobenzenesulfonic Acid Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAN mRNA]decreases reaction|increases expression 18200517
D014302 Trinitrobenzenesulfonic Acid Trinitrobenzenesulfonic Acid results in increased expression of VCAN mRNAincreases expression 18200517
D014415 Tunicamycin Tunicamycin results in decreased expression of VCAN mRNAdecreases expression 17127020
D014415 Tunicamycin Tunicamycin results in increased expression of VCAN mRNAincreases expression 17127020
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.7014514962 15322242 11752688
MESH:D055371 Acute Lung Injury pirinixic acid 2.9718653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 1.9520464547 20127859
MESH:D000236 Adenoma Benzo(a)pyrene 2.576695378
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.3916434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.3916835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.5515276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.7517306315 16712894
MESH:D019973 Alcohol-Related Disorders Curcumin 4.9317887948
MESH:D000544 Alzheimer Disease Curcumin 4.4415590663
MESH:D000544 Alzheimer Disease rosiglitazone 4.4419621015
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8111748828
MESH:D000799 Angioedema Astemizole 5.512883202
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.9219183758
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 3.9817460149
MESH:D001169 Arthritis, Experimental Dexamethasone 7.6917659584
MESH:D001169 Arthritis, Experimental rofecoxib 7.6916690336
MESH:D001172 Arthritis, Rheumatoid Curcumin 2.7016807698
MESH:D050197 Atherosclerosis Curcumin 3.2318704882
MESH:D001327 Autoimmune Diseases Curcumin 4.3419761891
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.3119483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.3112125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6415340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6715746008
MESH:D019046 Bone Marrow Neoplasms Etoposide 5.0114601052
MESH:D001919 Bradycardia Phenylephrine 4.3915306635
MESH:D002545 Brain Ischemia Curcumin 4.1816770732
MESH:D001932 Brain Neoplasms Curcumin 3.8017596214
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.9620146248 17474063
MESH:D001943 Breast Neoplasms Curcumin 1.9618462866 19250217 18593918 16243823
MESH:D001943 Breast Neoplasms Etoposide 1.9616322251
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9620435547
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.6316124888 15673190 16097048 15721981 10355542 16192424 3786805 16050911 18705752 15700767 16011737 16227642
MESH:D002277 Carcinoma Curcumin 7.8818593918
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.8816835633
MESH:D003528 Carcinoma, Adenoid Cystic marker/mechanism 16762588
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 4.4921507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 4.4918788625
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 4.4917306315 15276417 16507464
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 2.9318414057
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 7.3120419170
MESH:D002294 Carcinoma, Squamous Cell Curcumin 7.3118462866
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 7.3118572023
MESH:D006332 Cardiomegaly Phenylephrine 6.6016170337 17124262 11754973 17287366 11179087 15728586
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.6018850075 18670907 16120746
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 2.8919524636 20056578
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.0316835633
MESH:D002779 Cholestasis pirinixic acid 2.7119176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0416354765 12621046 15668235 15340226 8697196
MESH:D003092 Colitis Curcumin 9.4516804969 18200517 16782535
MESH:D003092 Colitis Trinitrobenzenesulfonic Acid 9.4517936198 16804969 17991707 16474422 11698051 16782535 18200517 16867261 18023891
MESH:D003093 Colitis, Ulcerative Trinitrobenzenesulfonic Acid 3.3917276891
MESH:D003103 Coloboma Curcumin 4.4118809619
MESH:D003110 Colonic Neoplasms Curcumin 5.9119359593 16340194
MESH:D003110 Colonic Neoplasms Dexamethasone 5.9115824018
MESH:D003110 Colonic Neoplasms rofecoxib 5.9112902858
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9314669216 17141729
MESH:D016510 Corneal Neovascularization Curcumin 4.7518497527
MESH:D019465 Craniofacial Abnormalities Dexamethasone 2.5717728286
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.5710048152 15322242 20055451
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 3.2612438553
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3618249437
MESH:D003920 Diabetes Mellitus rosiglitazone 4.1717446233
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 7.0118403477
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 7.0112642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 7.0117107852
MESH:D003928 Diabetic Nephropathies Curcumin 3.8818204486
MESH:D003967 Diarrhea Dexamethasone 3.557237001
MESH:D004244 Dizziness Astemizole 6.313105558
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 3.582869522 16177239 6884620 7440962 7179309 15998439 7120509 15968718 3732212 4309450 10092053 17522070 16227642 11566570 10915739 6623471 3786805 19085960 21278145 9327722 19336974 15027814
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.5820420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6511462148
MESH:D004381 Duodenal Ulcer Curcumin 3.9017351913
MESH:D004485 Eczema Dexamethasone 4.3112438553
MESH:D004487 Edema Dexamethasone 15.3319703484
MESH:D004487 Edema pirinixic acid 15.3312083418
MESH:D004487 Edema rosiglitazone 15.3312083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 15.3312711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.7515322242 18230668 16714409
MESH:D004715 Endometriosis rofecoxib 8.8815652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 8.889294722 10568697
MESH:D004802 Eosinophilia Astemizole 4.651355641
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 1.9716530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9011564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 17.6915959796 61145 16239168 16045604 19224547 17595544 12631006 12795759
MESH:D005234 Fatty Liver Curcumin 17.6919297423
MESH:D005234 Fatty Liver pirinixic acid 17.6920131406 19236843
MESH:D005234 Fatty Liver rosiglitazone 17.6919196556
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3111858732
MESH:D005355 Fibrosis Carbon Tetrachloride 19.9718705752
MESH:D005355 Fibrosis Curcumin 19.9718705752
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 19.9720067830
MESH:D005355 Fibrosis Trinitrobenzenesulfonic Acid 19.9717994277
MESH:D005499 Folliculitis Astemizole 5.771671328
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.5418462866
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.5316452187
MESH:D005909 Glioblastoma Curcumin 3.3817596214
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4410696789
MESH:D006258 Head and Neck Neoplasms Curcumin 3.5518462866 18829502
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.1820471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.1810048152 11294989
MESH:D006331 Heart Diseases Mitoxantrone 4.0516019553
MESH:D006333 Heart Failure pirinixic acid 2.4420558911
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2011000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.4519900420 19110552
MESH:D006529 Hepatomegaly pirinixic acid 7.7619176532 19772884 16221962 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.7612621046 15340226 16120746
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.8917701891
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 3.027520565
MESH:D006561 Herpes Simplex Etoposide 4.4110809021
MESH:D006689 Hodgkin Disease Etoposide 7.2217606976 15147373 16135485 16200630 18180244
MESH:D006689 Hodgkin Disease sodium arsenite 7.2212676792
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.8918606429 15340226 8697196 16959395 16354765
MESH:D006930 Hyperalgesia rosiglitazone 3.8012083418
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.3816899240
MESH:D006937 Hypercholesterolemia Curcumin 3.9118704882
MESH:D006943 Hyperglycemia pirinixic acid 3.0520558911
MESH:D006973 Hypertension Dexamethasone 8.3917042910
MESH:D006973 Hypertension Phenylephrine 8.398949925 12717712
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.3918850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.9415338365
MESH:D006984 Hypertrophy Phenylephrine 4.4212791704 18502941
MESH:D007077 Ileal Diseases 1-Methyl-3-isobutylxanthine 5.2918306037
MESH:D007248 Infertility, Male sodium arsenite 2.8915346721 12646999
MESH:D007249 Inflammation Curcumin 11.3818403477 16956363 17151092
MESH:D007249 Inflammation Dexamethasone 11.388960868 11099482
MESH:D007249 Inflammation rosiglitazone 11.3812083418
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 11.3812200463 12878042
MESH:D015212 Inflammatory Bowel Diseases Curcumin 6.4918596194 18200517
MESH:D015212 Inflammatory Bowel Diseases Trinitrobenzenesulfonic Acid 6.4918200517
MESH:D007333 Insulin Resistance pirinixic acid 7.1816306350
MESH:D007333 Insulin Resistance rosiglitazone 7.1816306350
MESH:D007410 Intestinal Diseases rofecoxib 9.9515831440
MESH:D007410 Intestinal Diseases Trinitrobenzenesulfonic Acid 9.9517994277
MESH:D007414 Intestinal Neoplasms Curcumin 4.0910783313
MESH:D007417 Intestinal Polyps rofecoxib 5.2211245490
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2016580747
MESH:D007579 Jejunal Diseases 1-Methyl-3-isobutylxanthine 5.2918306037
MESH:D007674 Kidney Diseases sodium arsenite 2.7220008137
MESH:D007889 Leiomyoma Curcumin 4.4318555241
MESH:D007938 Leukemia Curcumin 3.1718462866
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Mitoxantrone 3.7218172266
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 4.0716106398
MESH:D015458 Leukemia, T-Cell Curcumin 4.6116106398
MESH:D017513 Lichen Nitidus Astemizole 6.312563723
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 2.7316239168 17334410 11408273 21278145 17174718 11903743 16943688 16221502 17157831
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 10.6412632512 18472094 15123356 16015684 17805973 15893842 18156304 18317297 15338365 14512876 16027843 15370692 17721639 11481614 13678700 18395914 12632514 12666154 16248980 17823541 15673190 18705752 18210741 17900296 15996030 16116963 18187930 18420326 12445421 17557913 12667390 18277467 16192424 14716833 18205269 16033810 17525996 14716496 12958196 17565644 17640975 18472332 18418968 17922224 18339082 16011737 15730626 17976157 15876570 14620537 12586293 18006644 15362042 17631135 17766677 18263696 10355542 15959796 18429990 15057751 12741479 15818738 18279442 17761835 17708605 14748882 17869086 18395095 15925388 17481882 12649538 14724832 18054572 16638106 17698563 18166357 18481824 12546737 17714472 16097048 18251166 17944888 18376398 16136751 12898905 18412020 12389079 15052691 15650968 15931870 12609069 20821823 12445418
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 10.6418006644 18705752 17355460
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 10.6416718785
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 10.6415474484
MESH:D008106 Liver Cirrhosis, Experimental rofecoxib 10.6417565644
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 10.6417347453 15980055
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 10.6412878042
MESH:D008107 Liver Diseases Carbon Tetrachloride 4.1315830285 16246199 16964402 17285989 15720792
MESH:D008107 Liver Diseases Curcumin 4.1316956363
MESH:D017093 Liver Failure Carbon Tetrachloride 4.0115123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.5616899240 14706259
MESH:D008113 Liver Neoplasms Aflatoxin B1 17.249163691 15890375 2125692 18177683
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 17.2420195826 21137059
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 17.2419294768
MESH:D008113 Liver Neoplasms pirinixic acid 17.2416377806 20007298 15890375
MESH:D008113 Liver Neoplasms sodium arsenite 17.2415276417 16712894
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 17.2416984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 9.268603461
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 9.2612014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 9.2612151625
MESH:D008133 Long QT Syndrome Astemizole 4.4818472280 11989578
MESH:D008171 Lung Diseases sodium arsenite 3.0719095001
MESH:D008175 Lung Neoplasms Aflatoxin B1 8.3114755239
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 8.3118816296 17053015 18569708 18520028 20869020 20464547 20064080 6695378 20135361
MESH:D008175 Lung Neoplasms Curcumin 8.3116243823 19359593 18462866
MESH:D008175 Lung Neoplasms Dexamethasone 8.3115824018 11195469
MESH:D008175 Lung Neoplasms sodium arsenite 8.3117306315 19931552 17077188 15276417 16712894
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 8.3119555203 11884234
MESH:D008223 Lymphoma Curcumin 7.6018462866
MESH:D008223 Lymphoma Etoposide 7.6012556972 12854902
MESH:D016399 Lymphoma, T-Cell Curcumin 4.5416173963
MESH:D008288 Malaria Astemizole 4.6416816845
MESH:D008325 Mammary Neoplasms, Experimental Corticosterone 6.3212807724
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 6.3216827153
MESH:D008545 Melanoma Curcumin 3.4317885582 18462866
MESH:D008545 Melanoma sodium arsenite 3.4316487513 19082730
MESH:D008569 Memory Disorders Curcumin 4.0117263510
MESH:D024821 Metabolic Syndrome X rosiglitazone 4.2517261469
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.0716381670
MESH:D009101 Multiple Myeloma Curcumin 7.2319372569
MESH:D009101 Multiple Myeloma Dexamethasone 7.2315867202 16118317 15744524
MESH:D009134 Muscular Atrophy, Spinal Curcumin 4.7717962980
MESH:D009135 Muscular Diseases pirinixic acid 3.3616239165
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 3.469809623
MESH:D009203 Myocardial Infarction pirinixic acid 2.0819151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9012213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.8316411023
MESH:D009361 Neoplasm Invasiveness Curcumin 4.2218495463
MESH:D009369 Neoplasms Benzo(a)pyrene 11.2811141357
MESH:D009369 Neoplasms Mitoxantrone 11.2816640825
MESH:D009369 Neoplasms pirinixic acid 11.2817405874
MESH:D009369 Neoplasms sodium arsenite 11.2811559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.5220056578
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 4.3812497104
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.0714600291
MESH:D009423 Nervous System Neoplasms Curcumin 5.4818462866
MESH:D009436 Neural Tube Defects sodium arsenite 3.0512854658
MESH:D009447 Neuroblastoma Topotecan 3.7715176712
MESH:D009759 Nystagmus, Pathologic Astemizole 6.316135121
MESH:D009765 Obesity Curcumin 4.4819297423
MESH:D009765 Obesity pirinixic acid 4.4820558911
MESH:D010003 Osteoarthritis rofecoxib 4.2916690336
MESH:D010024 Osteoporosis Curcumin 3.3818719352
MESH:D010051 Ovarian Neoplasms Curcumin 4.9018462866 19020741
MESH:D010051 Ovarian Neoplasms sodium arsenite 4.9017306315 15276417
MESH:D010149 Pain, Postoperative rofecoxib 5.2418165598 16678543
MESH:D010190 Pancreatic Neoplasms Curcumin 5.5619401701 19196508 17440100
MESH:D010190 Pancreatic Neoplasms Etoposide 5.5619003803
MESH:D010195 Pancreatitis Trinitrobenzenesulfonic Acid 4.0617698068
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1012520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4118163543
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.4621297632
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.0411222880 11118676 11399792 11896295
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 1.9217292933
MESH:D011471 Prostatic Neoplasms Curcumin 1.9218226269 10851300 15129424 12497104 18156803 18769126 11398177
MESH:D011471 Prostatic Neoplasms Etoposide 1.9217172428
MESH:D011471 Prostatic Neoplasms Hyaluronic Acid 1.9216864594
MESH:D011471 Prostatic Neoplasms sodium arsenite 1.9216039940
MESH:D011656 Pulmonary Emphysema Curcumin 4.3919168576
MESH:D015427 Reperfusion Injury pirinixic acid 2.3119058328
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 8.8318379247 10666014
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 8.8318379247 11700416
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6918990726
MESH:D012221 Rhinitis, Allergic, Perennial Astemizole 5.2810822083
MESH:D012468 Salivary Gland Neoplasms marker/mechanism 16762588
MESH:D012509 Sarcoma Curcumin 3.9818462866
MESH:D012512 Sarcoma, Ewing's Etoposide 4.5614601052
MESH:D018805 Sepsis Curcumin 3.9518389075
MESH:D012852 Sinusitis Phenylephrine 4.557327846
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 12.9710029692 19755658
MESH:D012878 Skin Neoplasms sodium arsenite 12.9718572023 19524636
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 12.978532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 12.9716192470
MESH:D016135 Spinal Dysraphism sodium arsenite 3.6812854658
MESH:D013272 Stomach Diseases Dexamethasone 4.1715472012
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.5520155912 2093021
MESH:D013276 Stomach Ulcer Curcumin 7.0816631530 19188055
MESH:D013276 Stomach Ulcer Dexamethasone 7.0815138204
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.7512697716
MESH:D016171 Torsades de Pointes Astemizole 5.059583453 8256756
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 8.0317053015
MESH:D001749 Urinary Bladder Neoplasms Curcumin 8.0318593936
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 8.0316712894 16452187 11723127 17306315
MESH:D014565 Urogenital Neoplasms Curcumin 5.1118462866
MESH:D014581 Urticaria Astemizole 4.652565098 2147912 3097109 1683191 2885854 1976298 2568013 2568189 3080510 2859714 3134034 2883202
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 3.6311813266
MESH:D014605 Uveitis Dexamethasone 4.671336536
MESH:D014652 Vascular Diseases sodium arsenite 4.2717056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4412125929
MESH:D014717 Vertigo Astemizole 6.313105558
OMIM:143200 WAGNER SYNDROME 1 marker/mechanism
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1015886252
Pathway ID Pathway Name
KEGG:04514 Cell adhesion molecules (CAMs)
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB03684 - 2-Methyl-2,4-Pentanediol
No data
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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