AutismKB 2.0

Annotation Detail for FBXL16


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Basic Information Top
Gene Symbol:FBXL16 ( C16orf22,FLJ33735,Fbl16,MGC33974,c380A1.1 )
Gene Full Name: F-box and leucine-rich repeat protein 16
Band: 16p13.3
Quick LinksEntrez ID:146330; OMIM: 609082; Uniprot ID:FXL16_HUMAN; ENSEMBL ID: ENSG00000127585; HGNC ID: 14150
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
D013196 Dihydrotestosterone Dihydrotestosterone results in decreased expression of FBXL16 mRNAdecreases expression 16631469
D004041 Dietary Fats Dietary Fats results in increased expression of FBXL16 mRNAincreases expression 18042831
C041786 palm oil palm oil results in increased expression of FBXL16 mRNAincreases expression 18042831
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D001161 Arteriosclerosis Dietary Fats 4.5415238619
MESH:D001943 Breast Neoplasms Dietary Fats 2.2420435547
MESH:D050171 Dyslipidemias Dietary Fats 3.7618367378
MESH:D005234 Fatty Liver Dietary Fats 3.7219004024 19551842 17967931 18296743
MESH:D005355 Fibrosis Dietary Fats 4.1718296743
MESH:D006937 Hypercholesterolemia Dietary Fats 4.0821332399
MESH:D006949 Hyperlipidemias Dietary Fats 4.1421332399
MESH:D007249 Inflammation Dietary Fats 2.6220412841
MESH:D007333 Insulin Resistance Dietary Fats 3.3718457598 11836018
MESH:D008103 Liver Cirrhosis Dietary Fats 3.0918296743
MESH:D009765 Obesity Dietary Fats 2.3618457598 21332399 16723640 17217161 11836018 18674790 20132043 19632207 20518802
MESH:D015430 Weight Gain Dietary Fats 4.1516723640
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018