AutismKB 2.0

Annotation Detail for CSRP2


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Basic Information Top
Gene Symbol:CSRP2 ( CRP2,LMO5,SmLIM )
Gene Full Name: cysteine and glycine-rich protein 2
Band: 12q21.2
Quick LinksEntrez ID:1466; OMIM: 601871; Uniprot ID:CSRP2_HUMAN; ENSEMBL ID: ENSG00000175183; HGNC ID: 2470
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
200116ATF-2 transcription factor network
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene results in increased expression of CSRP2 mRNAincreases expression 20406850
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of CSRP2 mRNAaffects expression 21346803
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane affects the expression of CSRP2 mRNAaffects expression 18648102
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CSRP2 mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in decreased expression of CSRP2 mRNAdecreases expression 19128835
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of CSRP2 mRNAdecreases expression 20064835
C095105 bexarotene bexarotene results in decreased expression of CSRP2 mRNAdecreases expression 16648578
C459604 candoxin candoxin results in decreased expression of CSRP2 mRNAdecreases expression 16309724
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of CSRP2 mRNAincreases expression 17484886
D003345 Corticosterone Corticosterone results in increased expression of CSRP2 mRNAincreases expression 15755911
D016572 Cyclosporine Cyclosporine results in decreased expression of CSRP2 mRNAdecreases expression 20106945
D004041 Dietary Fats Dietary Fats results in increased expression of CSRP2 mRNAincreases expression 18042831
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CSRP2 mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of CSRP2 mRNAdecreases expression 12655037
D005419 Flavonoids Flavonoids results in increased expression of CSRP2 mRNAincreases expression 18035473
C056507 gemcitabine gemcitabine results in increased expression of CSRP2 mRNAincreases expression 17039268
D008748 Methylcholanthrene Methylcholanthrene results in increased expression of CSRP2 mRNAincreases expression 20713471
D009151 Mustard Gas Mustard Gas results in increased expression of CSRP2 mRNAincreases expression 15674844
C041786 palm oil palm oil results in increased expression of CSRP2 mRNAincreases expression 18042831
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of CSRP2 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of CSRP2 mRNAincreases expression 19482888
D010656 Phenylephrine Phenylephrine results in increased expression of CSRP2 mRNAincreases expression 18158353
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of CSRP2 mRNAaffects binding|decreases expression|increases activity 19710929
C006253 pirinixic acid pirinixic acid results in decreased expression of CSRP2 mRNAdecreases expression 17426115
16221962
C006253 pirinixic acid pirinixic acid results in increased expression of CSRP2 mRNAincreases expression 18301758
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CSRP2 mRNAaffects cotreatment|increases expression 17942748
D024505 Tocopherols Tocopherols results in increased expression of CSRP2 mRNAincreases expression 17056531
C496197 trans-10,cis-12-conjugated linoleic acid trans-10,cis-12-conjugated linoleic acid results in decreased expression of CSRP2 mRNAdecreases expression 17951470
D014212 Tretinoin Tretinoin results in decreased expression of CSRP2 mRNAdecreases expression 16604517
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 7.726195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.7211752688 14514962 15322242
MESH:D000138 Acidosis Ammonium Chloride 3.3918287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.7717505938
MESH:D055371 Acute Lung Injury pirinixic acid 2.9618653653
MESH:D000230 Adenocarcinoma arsenic trioxide 6.7711798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 6.7720127859 20464547
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 6.7714692618
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 10.653712494
MESH:D000236 Adenoma Benzo(a)pyrene 10.656695378
MESH:D000236 Adenoma Methylcholanthrene 10.656695378 10545420
MESH:D018248 Adenoma, Liver Cell Phenobarbital 16.2917620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 16.2916434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 16.2916835633
MESH:D000505 Alopecia Tretinoin 3.4815955085
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8011748828
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.9019183758
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 3.9617460149
MESH:D001161 Arteriosclerosis Dietary Fats 9.3415238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.3411256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.8615885639
MESH:D001169 Arthritis, Experimental Tretinoin 6.8616412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2316292516
MESH:D001249 Asthma Mustard Gas 4.8010378619
MESH:D001249 Asthma Tretinoin 4.8016456186
MESH:D050197 Atherosclerosis Methylcholanthrene 3.3511922910
MESH:D001471 Barrett Esophagus Tretinoin 4.2416935849
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.8511289319 1440618
MESH:D001768 Blister Mustard Gas 4.9919167455
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 20.6616206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 20.6619483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 20.6612125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 20.6616206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6515746008
MESH:D001919 Bradycardia Phenylephrine 4.3715306635
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 3.6620146248 17474063
MESH:D001943 Breast Neoplasms bexarotene 3.6616818667 16344269
MESH:D001943 Breast Neoplasms Dietary Fats 3.6620435547
MESH:D001943 Breast Neoplasms gemcitabine 3.6617039268 18382427
MESH:D001943 Breast Neoplasms Methylcholanthrene 3.6617474063
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 3.6620435547
MESH:D001943 Breast Neoplasms Tretinoin 3.6616873071 16443354 16166294
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.9915286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.8017687719 10378619
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.4216813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.1711589617
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.6116227642 16050911 15673190 16192424 15721981 3786805 15700767 16011737 18705752 16097048 16124888 10355542
MESH:D002277 Carcinoma Methylcholanthrene 7.8810545420
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.8816835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.9916168501
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 11.0216705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 11.023581430 7296757
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 11.0214691202 15073043 16217749 11135700 15553829
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 11.0218788625
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 11.026705139 1701930 20935162 17173139 20007298
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 11.021917145
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 3.1716247446
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.7019014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.607296757
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.9712490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.4020419170
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 4.4016051514 16096774
MESH:D006332 Cardiomegaly Phenylephrine 6.5715728586 16170337 11179087 17287366 11754973 17124262
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.5718850075 18670907 16120746
MESH:D002386 Cataract Tretinoin 2.9917460283
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 15.076135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 15.077505956
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 15.0712371664
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 15.0716192471
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.084080065
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.4216129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.0216835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 18.1719486331 9022650
MESH:D002779 Cholestasis Cyclosporine 18.1719486331
MESH:D002779 Cholestasis Ethinyl Estradiol 18.1715861022 11677210 16105132 17681005 16919318 17333356 17110522
MESH:D002779 Cholestasis pirinixic acid 18.1719176532
MESH:D002822 Choriocarcinoma Tretinoin 4.9916461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.5315340226 8697196 15668235 16354765 12621046
MESH:D002972 Cleft Palate Tretinoin 5.539407595
MESH:D003092 Colitis Tretinoin 3.5317035595
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9117141729 14669216
MESH:D023903 Coronary Restenosis arsenic trioxide 4.0212609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.6510525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.6510048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Tretinoin 3.659142499 9664655 9224671 17551590 8800419 9125849 9211117 16925845 10589399 14991402
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.8518551238
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.9315213294
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.6414531868 2524372 18759878 11906362 8156756 11298694 12868966 8970840
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3518249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.333621924 2952479
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6317107852
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 8.5321346803 18551238
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 8.537440962 9022650 1440618 6679447 18289764 9653073 18692083 11289319 18648102 16192314 8291058 6482804 9328219
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 8.536884620 9327722 10092053 15968718 21278145 4309450 2869522 10915739 19336974 17522070 7440962 16227642 6623471 16177239 3786805 19085960 7179309 7120509 15027814 15998439 3732212 11566570
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 8.5320420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6311462148
MESH:D050171 Dyslipidemias Dietary Fats 3.3318367378
MESH:D004421 Dystonia Phenobarbital 3.841851702
MESH:D004487 Edema Mustard Gas 10.5311428647 9260866 11428631 11402378
MESH:D004487 Edema pirinixic acid 10.5312083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 10.5312711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 11.3716714409 15322242 18230668
MESH:D004489 Edema, Cardiac Tretinoin 11.3718230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.0212538720
MESH:D016889 Endometrial Neoplasms Tretinoin 3.0016569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.879294722 10568697
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.943659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.7011558140 3922381
MESH:D004827 Epilepsy Phenobarbital 2.8020417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.406401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.087750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.853659116
MESH:D004890 Erythema Mustard Gas 4.999357497
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 6.953581430
MESH:D004938 Esophageal Neoplasms arsenic trioxide 6.9512903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 6.9516530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.4111564622
MESH:D005124 Eye Abnormalities Tretinoin 8.4116938888 9664655
MESH:D005234 Fatty Liver arsenic trioxide 28.6815073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 28.6812631006 16045604 15959796 17595544 12795759 16239168 61145 19224547
MESH:D005234 Fatty Liver Cyclosporine 28.6819224547
MESH:D005234 Fatty Liver Dietary Fats 28.6817967931 19551842 18296743 19004024
MESH:D005234 Fatty Liver Ethinyl Estradiol 28.6815345470
MESH:D005234 Fatty Liver pirinixic acid 28.6820131406 19236843
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.2911858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.856705139
MESH:D005354 Fibrosarcoma Methylcholanthrene 4.7714633661 10962813
MESH:D005355 Fibrosis Carbon Tetrachloride 25.9118705752
MESH:D005355 Fibrosis Cyclosporine 25.9112168785 12639820
MESH:D005355 Fibrosis Dietary Fats 25.9118296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 25.9120067830
MESH:D005355 Fibrosis Tretinoin 25.9117994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.1016904648
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.058708960
MESH:D005909 Glioblastoma Tretinoin 2.9017312396
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.887505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4210696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.0716096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.9916084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 10.5720471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 10.5711294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 10.579664655 14991402
MESH:D006333 Heart Failure pirinixic acid 2.4320558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.2515720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.1811000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 8.676705139
MESH:D006505 Hepatitis Carbon Tetrachloride 8.6719110552 19900420
MESH:D006529 Hepatomegaly Phenobarbital 13.3916109766
MESH:D006529 Hepatomegaly pirinixic acid 13.3916221962 19772884 18467677 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 13.3915340226 16120746 12621046
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.878697196 16959395 15340226 16354765 18606429
MESH:D006930 Hyperalgesia Tretinoin 3.0816870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.3616899240
MESH:D006937 Hypercholesterolemia Dietary Fats 3.4421332399
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.4016778211
MESH:D006943 Hyperglycemia pirinixic acid 3.0320558911
MESH:D006949 Hyperlipidemias Dietary Fats 3.4521332399
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.7715034207
MESH:D006973 Hypertension Cyclosporine 8.2310903974
MESH:D006973 Hypertension Phenylephrine 8.238949925 12717712
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.2318670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.9215338365
MESH:D006984 Hypertrophy Phenylephrine 4.4018502941 12791704
MESH:D007021 Hypospadias Ethinyl Estradiol 3.6416945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3012013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.3717937319
MESH:D007249 Inflammation Dietary Fats 11.2520412841
MESH:D007249 Inflammation Flavonoids 11.2517296493
MESH:D007249 Inflammation Mustard Gas 11.259260866 17524151 11402378 8975870 11428620 11428631 16001271 9357497 11428647
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 11.2512878042 12200463
MESH:D007333 Insulin Resistance Dietary Fats 6.8811836018 18457598
MESH:D007333 Insulin Resistance pirinixic acid 6.8816306350
MESH:D007410 Intestinal Diseases Tretinoin 3.6017994277
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.859022650 8074119
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.4116580747
MESH:D007569 Jaw Abnormalities Tretinoin 9.4117551590 15992940
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.2715604871
MESH:D007674 Kidney Diseases Cyclosporine 2.248314463 10903974 18776723
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 11.5516705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 11.556582329
MESH:D007680 Kidney Neoplasms Cyclosporine 11.5512371664
MESH:D007938 Leukemia arsenic trioxide 6.0615070760
MESH:D007938 Leukemia Tretinoin 6.0617143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.6417077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.1316972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.3014633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 8.9519077051
MESH:D007951 Leukemia, Myeloid Tretinoin 8.9516482212 19285840 16932348
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.7719850784 20471514 16968895 17050201 16467208
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 3.7716294345 19850784 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 7.2619642359 19035177 17107899 16823087 12018890 11468182 17712046 9834237 12712474 16112521 15336539 16891316 19225113 15213294 17217047 19075265 16331271 17649720 15622746 12679006 16966277 17869043 11161223 15748426 16330433
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 7.2619642359 16935935 16891316 19029980 19035177 17649720 9834237 12679006 19075265 19225113 16788101 16140955 17368321 17294898 17339181 15748426 16766008 16823087 16331271 17361223 17107899 17301526 17712046 17217047 17506722
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.1916882451
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.199224671
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 10.4816943688 16239168 11408273 17157831 11903743 17334410 17174718 16221502 21278145
MESH:D008103 Liver Cirrhosis Dietary Fats 10.4818296743
MESH:D008103 Liver Cirrhosis Phenobarbital 10.4821047994
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.0915034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 4.7518187930 16011737 18339082 15959796 12586293 18472332 20821823 17869086 12741479 12649538 18395095 14748882 12609069 16638106 11481614 17481882 15650968 17922224 18420326 18263696 12958196 17565644 15893842 18317297 15996030 15931870 18705752 16136751 15057751 16116963 13678700 17976157 17944888 15052691 18205269 15818738 16097048 18006644 14724832 18412020 17631135 17525996 12632512 15730626 16192424 17640975 18481824 18210741 18166357 18156304 14716833 18376398 17766677 10355542 17900296 17708605 15123356 12632514 16033810 18054572 15362042 15925388 15876570 14716496 16015684 18279442 18472094 12445418 12389079 18251166 18429990 12898905 18277467 17557913 15338365 15673190 12546737 14512876 17698563 16027843 17761835 12445421 17805973 12667390 12666154 14620537 16248980 17721639 18418968 15370692 17714472 17823541 18395914
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.7515474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.7512878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 4.7516248980 18397230
MESH:D008107 Liver Diseases Carbon Tetrachloride 3.9516964402 15830285 17285989 16246199 15720792
MESH:D008107 Liver Diseases Phenobarbital 3.9519363144
MESH:D017093 Liver Failure Carbon Tetrachloride 3.9915123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.5416899240 14706259
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 20.917678174
MESH:D008113 Liver Neoplasms arsenic trioxide 20.9114682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 20.9121137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 20.9119294768
MESH:D008113 Liver Neoplasms Phenobarbital 20.9121047994 8742319 15975961 19482888 19073162 19812893
MESH:D008113 Liver Neoplasms pirinixic acid 20.9116377806 20007298 15890375
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 20.9116984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 26.652876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 26.656587162 3712494 1399818 598648
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 26.6520377131
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 26.6512014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 26.65598648 1399818
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 26.656150874 17172636 2563599 18308698 1399818
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 26.6512151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.2215213294
MESH:D008171 Lung Diseases Mustard Gas 3.3418702808 18161513
MESH:D008175 Lung Neoplasms arsenic trioxide 8.2811798837 19825857
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 8.2818816296 20464547 20869020 18520028 6695378 17053015 18569708 20064080 20135361
MESH:D008175 Lung Neoplasms bexarotene 8.2817849452
MESH:D008175 Lung Neoplasms Methylcholanthrene 8.287750092 17909032 9230183 20512841 16337739 21163286 20970405 6695378 16271038 10545420 1399818 11893704 15390079
MESH:D008175 Lung Neoplasms Mustard Gas 8.288781369 3148597
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 8.2811884234 19555203
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 4.9811161223
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 9.7515591091 19196722 19196723
MESH:D008325 Mammary Neoplasms, Experimental Corticosterone 9.7512807724
MESH:D008325 Mammary Neoplasms, Experimental Tocopherols 9.7517927505
MESH:D008527 Medulloblastoma Tretinoin 2.7217453147
MESH:D008545 Melanoma Tretinoin 1.9216752155
MESH:D008591 Meningomyelocele Tretinoin 4.2516940565
MESH:D008654 Mesothelioma Tocopherols 4.0415878867
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.6216801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.0616381670
MESH:D009101 Multiple Myeloma arsenic trioxide 2.9819417148 19549372 11468182 15949261 14977855
MESH:D009135 Muscular Diseases pirinixic acid 3.3416239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.5018349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 7.0716105982 16882451
MESH:D009190 Myelodysplastic Syndromes Tretinoin 7.0717596541
MESH:D009203 Myocardial Infarction pirinixic acid 2.0719151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.8812213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.8116411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.3017484760
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.697678174 18551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.7916624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.403581430
MESH:D009369 Neoplasms Benzo(a)pyrene 7.7011141357
MESH:D009369 Neoplasms pirinixic acid 7.7017405874
MESH:D009369 Neoplasms Tretinoin 7.7016946489 16594593
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 4.6119196722
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.2717954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.1419348381 18481113
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 8.9614600291
MESH:D009421 Nervous System Malformations Tretinoin 8.969125849
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 11.486679447
MESH:D009436 Neural Tube Defects arsenic trioxide 11.4810525206
MESH:D009436 Neural Tube Defects Tretinoin 11.489142499
MESH:D009503 Neutropenia Mustard Gas 3.817688884 16761898
MESH:D009765 Obesity Dietary Fats 4.2918674790 18457598 19632207 17217161 20518802 11836018 20132043 16723640 21332399
MESH:D009765 Obesity pirinixic acid 4.2920558911
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 8.3816049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 8.384026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.853988306
MESH:D010018 Osteomalacia Phenobarbital 4.1917016548
MESH:D010051 Ovarian Neoplasms arsenic trioxide 4.6916624393 19769630 12452020
MESH:D010051 Ovarian Neoplasms Tretinoin 4.6916936753
MESH:D010146 Pain Tretinoin 2.7716870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 11.8815580305
MESH:D010190 Pancreatic Neoplasms gemcitabine 11.8811504793 18383843 17440100 18992248 16929163
MESH:D010190 Pancreatic Neoplasms Phenobarbital 11.8816965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 11.8815976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5311578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.317296757
MESH:D010235 Paraganglioma arsenic trioxide 4.0019927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.0812520081
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.306228378
MESH:D011041 Poisoning Mustard Gas 3.6415727166
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.3918163543
MESH:D011230 Precancerous Conditions Cyclosporine 8.4912371664
MESH:D011230 Precancerous Conditions Phenobarbital 8.492563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.0211896295 11399792 11118676 11222880
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.7719131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.7717292933
MESH:D011471 Prostatic Neoplasms Tocopherols 2.7712504091
MESH:D011507 Proteinuria Tretinoin 3.4416636307
MESH:D011537 Pruritus Ethinyl Estradiol 8.9515861022 16919318
MESH:D011537 Pruritus Mustard Gas 8.9518058305
MESH:D019310 Pseudolymphoma Phenobarbital 4.3212752131
MESH:D011565 Psoriasis Cyclosporine 2.1716882103
MESH:D011625 Pterygium Tretinoin 4.6216723453
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.8617266442 17894541 17720292 10334151 17620002
MESH:D015427 Reperfusion Injury pirinixic acid 2.3019058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6718990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.253692021
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.9416283617 16116481
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.7916646077
MESH:D012640 Seizures 2,6-dinitrotoluene 5.5418551238
MESH:D012640 Seizures Phenobarbital 5.543137016 16876388 4039156 11442880
MESH:D003294 Seizures, Febrile Phenobarbital 4.656407741
MESH:D012852 Sinusitis Phenylephrine 4.537327846
MESH:D012871 Skin Diseases Mustard Gas 2.6712880345 15451306 16961503
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 8.9210029692 19755658
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 8.9216192470
MESH:D012878 Skin Neoplasms Tretinoin 8.9216467112
MESH:D013088 Spermatocele Ethinyl Estradiol 3.7716709447
MESH:D013274 Stomach Neoplasms arsenic trioxide 3.2517007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 3.2520155912 2093021
MESH:D013274 Stomach Neoplasms Tretinoin 3.2517261132
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.4611994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0115669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.7312697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 16.037505956 1399818 3712494 6582329 6587162
MESH:D013964 Thyroid Neoplasms arsenic trioxide 16.0319014326
MESH:D013964 Thyroid Neoplasms Phenobarbital 16.031399818
MESH:D013964 Thyroid Neoplasms Tretinoin 16.0316026305 17045167
MESH:D014062 Tongue Neoplasms Tretinoin 3.6416051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.7915213294
MESH:D014376 Tuberculosis Tretinoin 3.1216040207
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 11.3616049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 11.368074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 11.3612973940 20435036 12845720 11780464
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 11.3617053015
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.1510091137
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.5316129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.1314692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.4416752155
MESH:D014605 Uveitis Cyclosporine 3.811336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4212125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.3814671159 15869587
MESH:D014820 Vitiligo Tretinoin 3.8916761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.0815886252
MESH:D015430 Weight Gain Dietary Fats 3.5916723640
MESH:D009396 Wilms Tumor Tretinoin 3.8216287080
MESH:D014985 Xerophthalmia Cyclosporine 4.2717120751
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA26968
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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