AutismKB 2.0

Annotation Detail for RBFOX3


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Basic Information Top
Gene Symbol:RBFOX3 ( FLJ56884,FLJ58356,FOX-3,FOX3,HRNBP3,NEUN )
Gene Full Name: RNA binding protein, fox-1 homolog (C. elegans) 3
Band: 17q25.3
Quick LinksEntrez ID:146713; OMIM: NA; Uniprot ID:RFOX3_HUMAN; ENSEMBL ID: ENSG00000167281; HGNC ID: 27097
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D014212 Tretinoin [Tretinoin co-treated with SHH protein co-treated with FGF8 protein] results in increased expression of RBFOX3 proteinaffects cotreatment|increases expression 17085092
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000505 Alopecia Tretinoin 4.0715955085
MESH:D001169 Arthritis, Experimental Tretinoin 3.3716412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.3516292516
MESH:D001249 Asthma Tretinoin 2.4616456186
MESH:D001471 Barrett Esophagus Tretinoin 5.1916935849
MESH:D001778 Blood Coagulation Disorders Tretinoin 4.2416197459 16206674
MESH:D001943 Breast Neoplasms Tretinoin 2.2216873071 16443354 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 5.6816813970
MESH:D018236 Carcinoma, Embryonal Tretinoin 6.5816168501
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 1.931917145
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 2.4016096774 16051514
MESH:D002386 Cataract Tretinoin 3.3717460283
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 5.6816129372
MESH:D002822 Choriocarcinoma Tretinoin 6.5816461808
MESH:D002972 Cleft Palate Tretinoin 2.849407595
MESH:D003092 Colitis Tretinoin 4.6117035595
MESH:D019465 Craniofacial Abnormalities Tretinoin 1.849664655 9142499 8800419 17551590 9125849 10589399 14991402 9211117 9224671 16925845
MESH:D004489 Edema, Cardiac Tretinoin 5.8818230668
MESH:D016889 Endometrial Neoplasms Tretinoin 3.4316569247
MESH:D005124 Eye Abnormalities Tretinoin 3.9816938888 9664655
MESH:D005355 Fibrosis Tretinoin 4.4217994277
MESH:D005909 Glioblastoma Tretinoin 3.3317312396
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.5316096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 6.5816084493
MESH:D006330 Heart Defects, Congenital Tretinoin 3.1314991402 9664655
MESH:D006930 Hyperalgesia Tretinoin 3.6616870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 5.4816778211
MESH:D007410 Intestinal Diseases Tretinoin 4.6717994277
MESH:D007569 Jaw Abnormalities Tretinoin 4.5317551590 15992940
MESH:D007938 Leukemia Tretinoin 2.9917143497
MESH:D007951 Leukemia, Myeloid Tretinoin 4.3316482212 16932348 19285840
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.1419850784 16294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.4819035177 17294898 17301526 17506722 19642359 17361223 17339181 16788101 17368321 17649720 16935935 16823087 17107899 16891316 16766008 19075265 17217047 12679006 17712046 19029980 16140955 19225113 16331271 9834237 15748426
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.699224671
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 1.8218397230 16248980
MESH:D008527 Medulloblastoma Tretinoin 2.9417453147
MESH:D008545 Melanoma Tretinoin 1.9916752155
MESH:D008591 Meningomyelocele Tretinoin 5.3316940565
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.3417596541
MESH:D009369 Neoplasms Tretinoin 2.6216594593 16946489
MESH:D009421 Nervous System Malformations Tretinoin 4.569125849
MESH:D009436 Neural Tube Defects Tretinoin 3.389142499
MESH:D010051 Ovarian Neoplasms Tretinoin 2.4616936753
MESH:D010146 Pain Tretinoin 3.3816870215
MESH:D010190 Pancreatic Neoplasms Tretinoin 2.6015976015
MESH:D011507 Proteinuria Tretinoin 4.3016636307
MESH:D011625 Pterygium Tretinoin 5.8816723453
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.8016283617 16116481
MESH:D012878 Skin Neoplasms Tretinoin 2.8116467112
MESH:D013274 Stomach Neoplasms Tretinoin 1.8017261132
MESH:D013964 Thyroid Neoplasms Tretinoin 3.4516026305 17045167
MESH:D014062 Tongue Neoplasms Tretinoin 4.3616051514
MESH:D014376 Tuberculosis Tretinoin 3.5316040207
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 4.2516129372
MESH:D014604 Uveal Neoplasms Tretinoin 6.0316752155
MESH:D014820 Vitiligo Tretinoin 4.8416761959
MESH:D009396 Wilms Tumor Tretinoin 4.5016287080
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018