AutismKB 2.0

Annotation Detail for KIF18B


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Basic Information Top
Gene Symbol:KIF18B ( - )
Gene Full Name: kinesin family member 18B
Band: 17q21.31
Quick LinksEntrez ID:146909; OMIM: NA; Uniprot ID:; ENSEMBL ID: ENSG00000186185; HGNC ID: 27102
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of KIF18B mRNAaffects expression 17484886
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of KIF18B mRNAaffects expression 17351261
D014635 Valproic Acid Valproic Acid results in decreased expression of KIF18B mRNAdecreases expression 19101580
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 4.238875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 4.4119490988
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.8117505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8914692618
MESH:D000550 Amblyopia Valproic Acid 6.1017688650
MESH:D001008 Anxiety Disorders Valproic Acid 3.9417497229
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 4.1211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.9115885639
MESH:D001321 Autistic Disorder Valproic Acid 1.9817688650 20603192 18177632 19460635 16609825 18558336 18775368 18985861 18940202 18316065 17157402 15238991 19232924 17507914 18396377
MESH:D001714 Bipolar Disorder Valproic Acid 3.2617594078 20046352
MESH:D001848 Bone Diseases, Developmental Valproic Acid 3.668888407
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 4.4316011737 16227642 16124888 15721981 16050911 15700767 16097048 15673190 10355542 18705752 3786805 16192424
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 1.8618788625
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.8320734317
MESH:D002779 Cholestasis Ethinyl Estradiol 3.2016105132 17333356 16919318 11677210 17681005 17110522 15861022
MESH:D019465 Craniofacial Abnormalities Valproic Acid 1.918888407 17688650 16575769
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 4.297179309 7440962 6884620 21278145 11566570 2869522 10092053 19336974 3732212 15968718 6623471 4309450 15998439 9327722 15027814 17522070 7120509 16227642 3786805 16177239 10915739 19085960
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 4.2919641884 1733752
MESH:D004421 Dystonia Valproic Acid 4.581851702
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.7712538720
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.813659116 17275665
MESH:D004828 Epilepsies, Partial Valproic Acid 4.7816628512 3922381
MESH:D004827 Epilepsy Valproic Acid 3.1220417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 4.006426943 7562514 6254150
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.957750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.813659116
MESH:D005234 Fatty Liver Carbon Tetrachloride 16.0912795759 19224547 12631006 16045604 15959796 61145 17595544 16239168
MESH:D005234 Fatty Liver Ethinyl Estradiol 16.0915345470
MESH:D005234 Fatty Liver Valproic Acid 16.0914986274 19224547
MESH:D005315 Fetal Diseases Valproic Acid 5.7516575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.7118558336 8888407
MESH:D005355 Fibrosis Carbon Tetrachloride 4.1018705752
MESH:D006505 Hepatitis Carbon Tetrachloride 4.1819900420 19110552
MESH:D006849 Hydrocephalus Valproic Acid 5.6117688650
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 5.2716899240
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.7415338365
MESH:D007021 Hypospadias Ethinyl Estradiol 4.4616945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.9912013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.7617937319
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.2016294345 17596541
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 3.0217334410 11408273 11903743 16943688 21278145 17174718 17157831 16221502 16239168
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 1.7518395914 12445418 17557913 12666154 18376398 17823541 18412020 14512876 18251166 15370692 17714472 14716496 18166357 15730626 18205269 16638106 15959796 18210741 10355542 12649538 14716833 16248980 18429990 15925388 17766677 15931870 18395095 16033810 18156304 14620537 16116963 15673190 18317297 18006644 18279442 12389079 18187930 17922224 17631135 18472332 17976157 12632514 16011737 15818738 12741479 17698563 15893842 17761835 12445421 17481882 12546737 18472094 18481824 18054572 13678700 16136751 15996030 14748882 16097048 15338365 12586293 17805973 20821823 17869086 17721639 18277467 18263696 16015684 11481614 17708605 18420326 17900296 17944888 15362042 12609069 16192424 15876570 12958196 18705752 17525996 17565644 18418968 17640975 15123356 15650968 15052691 18339082 12632512 12898905 15057751 12667390 14724832 16027843
MESH:D008107 Liver Diseases Carbon Tetrachloride 2.1617285989 16964402 16246199 15830285 15720792
MESH:D017093 Liver Failure Carbon Tetrachloride 4.8215123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 4.1414706259 16899240
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 2.3519294768
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 2.8615583823 12014681
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 5.1317228818
MESH:D008881 Migraine Disorders Valproic Acid 3.5018765137 18803445
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.518888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.3717596541
MESH:D009436 Neural Tube Defects Valproic Acid 3.3916359493 8888407
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.2211578682
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 4.5720603192
MESH:D011537 Pruritus Ethinyl Estradiol 4.0515861022 16919318
MESH:D019310 Pseudolymphoma Valproic Acid 5.4112752131 11422049
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.7019155313
MESH:D012559 Schizophrenia Valproic Acid 2.1119110320 15737665
MESH:D012640 Seizures Valproic Acid 3.0211044598 15475178 14763951 17978042 1511512 16876388 3137016 11738929
MESH:D013088 Spermatocele Ethinyl Estradiol 4.8116709447
MESH:D016135 Spinal Dysraphism Valproic Acid 4.1319490988
MESH:D013226 Status Epilepticus Valproic Acid 5.4112833885
MESH:D019851 Thrombophilia Ethinyl Estradiol 4.1511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.5715669648
MESH:D014178 Translocation, Genetic Valproic Acid 6.1017262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 5.263119515
MESH:D014564 Urogenital Abnormalities Valproic Acid 5.308888407
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.8814692618
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 4.0214671159 15869587
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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