AutismKB 2.0

Annotation Detail for CST5


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Basic Information Top
Gene Symbol:CST5 ( MGC71922 )
Gene Full Name: cystatin D
Band: 20p11.21
Quick LinksEntrez ID:1473; OMIM: 123858; Uniprot ID:CYTD_HUMAN; ENSEMBL ID: ENSG00000170367; HGNC ID: 2477
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
No data
Desease Name
PHARMACOGENOMIC
response to TNF antagonist treatment
Desease Name
Response to TNF antagonist treatment
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D002330 Carmustine Carmustine results in decreased expression of CST5 mRNAdecreases expression 15980968
D004958 Estradiol Estradiol affects the expression of CST5 mRNAaffects expression 14699072
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Estradiol 2.1811473722
MESH:D001932 Brain Neoplasms Carmustine 4.8916187019
MESH:D001943 Breast Neoplasms Estradiol 2.1012948864 16675129 19861407 17261762 18497071 14630087 17289903 17018787
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 5.3516111702
MESH:D006528 Carcinoma, Hepatocellular Estradiol 1.8016924424
MESH:D002471 Cell Transformation, Neoplastic Estradiol 3.0918566989
MESH:D003928 Diabetic Nephropathies Estradiol 3.8819279558
MESH:D016889 Endometrial Neoplasms Estradiol 3.2819148513 11473722 18566989
MESH:D005909 Glioblastoma Carmustine 4.2216187019
MESH:D006558 Herpes Genitalis Estradiol 6.1015709030
MESH:D019584 Hot Flashes Estradiol 4.8217088409
MESH:D007333 Insulin Resistance Estradiol 3.2616393666 16627594
MESH:D007674 Kidney Diseases Estradiol 2.8315618244
MESH:D007680 Kidney Neoplasms Estradiol 3.4115610895
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 1.6914659978 14716833
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.8516891317 17203775 11807958 11408345
MESH:D020149 Manganese Poisoning Estradiol 5.5519453300
MESH:D008545 Melanoma Carmustine 2.9112393984
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.6616810080
MESH:D009389 Neovascularization, Pathologic Estradiol 4.6217289903
MESH:D009421 Nervous System Malformations Estradiol 4.3211399458 16427766
MESH:D010051 Ovarian Neoplasms Estradiol 2.3319401270
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 4.4420887781
MESH:D011471 Prostatic Neoplasms Estradiol 3.0116740699
MESH:D013978 Tibial Fractures Estradiol 5.7619048282
Pathway ID Pathway Name
KEGG:04970 Salivary secretion
Pharmacogenomics Knowledge Base Top
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018