Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
---|
D000082 |
Acetaminophen |
Acetaminophen affects the expression of ANKRD29 mRNA | affects expression | 17562736
|
C006632 |
arsenic trioxide |
arsenic trioxide results in decreased expression of ANKRD29 mRNA | decreases expression | 20458559
|
D015123 |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of ANKRD29 mRNA | increases expression | 20382639
|
D016572 |
Cyclosporine |
Cyclosporine results in decreased expression of ANKRD29 mRNA | decreases expression | 20106945
|
C006253 |
pirinixic acid |
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of ANKRD29 mRNA | affects binding|decreases expression|increases activity | 19710929
|
Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
---|
MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.52 | 18653653 |
MESH:D000230 |
Adenocarcinoma |
|
arsenic trioxide |
2.35 | 11798837 19825857 |
MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
4.02 | 16434500 |
MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.45 | 10982225 |
MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.40 | 18445737 |
MESH:D001778 |
Blood Coagulation Disorders |
|
arsenic trioxide |
10.27 | 16206674 |
MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
10.27 | 19483382 |
MESH:D002051 |
Burkitt Lymphoma |
|
arsenic trioxide |
4.73 | 11589617 |
MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
3.02 | 3084413 |
MESH:D006528 |
Carcinoma, Hepatocellular |
|
arsenic trioxide |
3.02 | 15073043 16217749 11135700 14691202 15553829 |
MESH:D002291 |
Carcinoma, Papillary |
|
arsenic trioxide |
5.49 | 19014326 |
MESH:D018288 |
Carcinoma, Small Cell |
|
arsenic trioxide |
4.47 | 12490120 |
MESH:D002386 |
Cataract |
|
Acetaminophen |
2.77 | 10977129 |
MESH:D002471 |
Cell Transformation, Neoplastic |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7.35 | 20889678 |
MESH:D002471 |
Cell Transformation, Neoplastic |
|
Cyclosporine |
7.35 | 12371664 |
MESH:D002779 |
Cholestasis |
|
Cyclosporine |
8.63 | 19486331 |
MESH:D002779 |
Cholestasis |
|
pirinixic acid |
8.63 | 19176532 |
MESH:D015179 |
Colorectal Neoplasms |
|
arsenic trioxide |
1.86 | 20501625 |
MESH:D023903 |
Coronary Restenosis |
|
arsenic trioxide |
4.63 | 12609071 |
MESH:D019465 |
Craniofacial Abnormalities |
|
arsenic trioxide |
1.89 | 10525206 |
MESH:D016757 |
Death, Sudden, Cardiac |
|
arsenic trioxide |
4.50 | 15213294 |
MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.56 | 18249437 |
MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
1.66 | 18071297 12705907 11421492 11287661 12958197 10663392 16081117 17906064 19370779 14725611 10774834 16781746 17522070 12153990 16109766 19739265 11461765 10915739 17562736 19164858 16393943 12594235 15968718 19420014 16177239 11743745 19085960 11739529 19416960 18713872 16227642 12540782 14986274 19923254 12392966 11529661 16485898 2444490 11834606 15619225 14550746 |
MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.71 | 19426721 |
MESH:D004487 |
Edema |
|
pirinixic acid |
2.85 | 12083418 |
MESH:D004938 |
Esophageal Neoplasms |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
4.70 | 20426865 |
MESH:D004938 |
Esophageal Neoplasms |
|
arsenic trioxide |
4.70 | 12903497 |
MESH:D005234 |
Fatty Liver |
|
arsenic trioxide |
15.33 | 15073043 |
MESH:D005234 |
Fatty Liver |
|
Cyclosporine |
15.33 | 19224547 |
MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
15.33 | 20131406 19236843 |
MESH:D005355 |
Fibrosis |
|
Cyclosporine |
3.62 | 12168785 12639820 |
MESH:D005706 |
Gallbladder Neoplasms |
|
arsenic trioxide |
4.70 | 16904648 |
MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.29 | 16983495 |
MESH:D005885 |
Gingival Hyperplasia |
|
Cyclosporine |
4.76 | 8708960 |
MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.73 | 20558911 |
MESH:D006457 |
Hemoglobinuria, Paroxysmal |
|
Cyclosporine |
4.96 | 15720958 |
MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.48 | 18467677 19176532 19772884 16221962 |
MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
2.99 | 16870215 |
MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.53 | 20558911 |
MESH:D006973 |
Hypertension |
|
Cyclosporine |
2.20 | 10903974 |
MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.85 | 16306350 |
MESH:D007638 |
Keratoconjunctivitis Sicca |
|
Cyclosporine |
5.05 | 15604871 |
MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
6.41 | 15629191 12587719 |
MESH:D007674 |
Kidney Diseases |
|
Cyclosporine |
6.41 | 8314463 10903974 18776723 |
MESH:D007680 |
Kidney Neoplasms |
|
Cyclosporine |
3.04 | 12371664 |
MESH:D007938 |
Leukemia |
|
arsenic trioxide |
2.98 | 15070760 |
MESH:D015459 |
Leukemia-Lymphoma, Adult T-Cell |
|
arsenic trioxide |
4.17 | 12560223 17077332 |
MESH:D007948 |
Leukemia, Monocytic, Acute |
|
arsenic trioxide |
4.85 | 16972261 |
MESH:D015464 |
Leukemia, Myelogenous, Chronic, BCR-ABL Positive |
|
arsenic trioxide |
3.69 | 14633726 |
MESH:D007951 |
Leukemia, Myeloid |
|
arsenic trioxide |
4.13 | 19077051 |
MESH:D015470 |
Leukemia, Myeloid, Acute |
|
arsenic trioxide |
2.18 | 17050201 16467208 20471514 16968895 19850784 |
MESH:D015473 |
Leukemia, Promyelocytic, Acute |
|
arsenic trioxide |
3.43 | 16330433 17869043 15336539 17217047 19035177 19225113 17712046 12018890 16331271 12679006 17107899 16966277 12712474 11161223 9834237 16891316 15748426 15622746 16112521 16823087 19642359 19075265 11468182 15213294 17649720 |
MESH:D015458 |
Leukemia, T-Cell |
|
arsenic trioxide |
4.79 | 16882451 |
MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
1.69 | 19784758 12969438 12587719 19014921 19460945 16611625 11587558 16610002 |
MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.58 | 16871587 17185352 |
MESH:D008113 |
Liver Neoplasms |
|
arsenic trioxide |
4.84 | 14682389 |
MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
4.84 | 15890375 20007298 16377806 |
MESH:D008114 |
Liver Neoplasms, Experimental |
|
arsenic trioxide |
2.93 | 20377131 |
MESH:D008133 |
Long QT Syndrome |
|
arsenic trioxide |
3.62 | 15213294 |
MESH:D008175 |
Lung Neoplasms |
|
arsenic trioxide |
1.87 | 19825857 11798837 |
MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
4.05 | 19513568 |
MESH:D008664 |
Metal Metabolism, Inborn Errors |
|
Cyclosporine |
5.40 | 16801185 |
MESH:D009101 |
Multiple Myeloma |
|
arsenic trioxide |
3.35 | 11468182 19417148 15949261 14977855 19549372 |
MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
3.99 | 16239165 |
MESH:D009182 |
Mycosis Fungoides |
|
arsenic trioxide |
5.28 | 18349030 |
MESH:D009190 |
Myelodysplastic Syndromes |
|
arsenic trioxide |
3.32 | 16105982 16882451 |
MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.26 | 19151258 |
MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.22 | 16411023 |
MESH:D009361 |
Neoplasm Invasiveness |
|
arsenic trioxide |
4.40 | 16624393 |
MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.09 | 17405874 |
MESH:D009402 |
Nephrosis, Lipoid |
|
Cyclosporine |
5.05 | 17954296 |
MESH:D009404 |
Nephrotic Syndrome |
|
Cyclosporine |
3.61 | 19348381 18481113 |
MESH:D009436 |
Neural Tube Defects |
|
arsenic trioxide |
3.33 | 10525206 |
MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.18 | 18514411 |
MESH:D009765 |
Obesity |
|
pirinixic acid |
1.88 | 20558911 |
MESH:D010051 |
Ovarian Neoplasms |
|
arsenic trioxide |
2.49 | 12452020 16624393 19769630 |
MESH:D010146 |
Pain |
|
Acetaminophen |
2.69 | 16870215 |
MESH:D010190 |
Pancreatic Neoplasms |
|
arsenic trioxide |
2.62 | 15580305 |
MESH:D010235 |
Paraganglioma |
|
arsenic trioxide |
4.57 | 19927285 |
MESH:D011230 |
Precancerous Conditions |
|
Cyclosporine |
3.55 | 12371664 |
MESH:D011471 |
Prostatic Neoplasms |
|
arsenic trioxide |
3.22 | 19131511 |
MESH:D011565 |
Psoriasis |
|
Cyclosporine |
2.32 | 16882103 |
MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.53 | 19058328 |
MESH:D012512 |
Sarcoma, Ewing's |
|
arsenic trioxide |
4.40 | 16646077 |
MESH:D013274 |
Stomach Neoplasms |
|
arsenic trioxide |
1.86 | 17007042 |
MESH:D013964 |
Thyroid Neoplasms |
|
arsenic trioxide |
3.36 | 19014326 |
MESH:D016171 |
Torsades de Pointes |
|
arsenic trioxide |
4.50 | 15213294 |
MESH:D001749 |
Urinary Bladder Neoplasms |
|
arsenic trioxide |
2.59 | 20435036 11780464 12845720 12973940 |
MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.38 | 10982225 |
MESH:D014605 |
Uveitis |
|
Cyclosporine |
4.59 | 1336536 |
MESH:D014985 |
Xerophthalmia |
|
Cyclosporine |
5.05 | 17120751 |