AutismKB 2.0

Annotation Detail for CTBP2


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Basic Information Top
Gene Symbol:CTBP2 ( - )
Gene Full Name: C-terminal binding protein 2
Band: 10q26.13
Quick LinksEntrez ID:1488; OMIM: 602619; Uniprot ID:CTBP2_HUMAN; ENSEMBL ID: ENSG00000175029; HGNC ID: 2495
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04310Wnt signaling pathway
hsa04330Notch signaling pathway
hsa05220Chronic myeloid leukemia
hsa05200Pathways in cancer
No data
No data
Pathway IDPathway Name
P00057Wnt signaling pathway
No data
Related Diseases/Disorders Top
No data
No data
Desease Name
prostate cancer
CANCER
Desease Name
Prostate cancer
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of CTBP2 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CTBP2 mRNAaffects expression 16483693
D001194 Asbestos Asbestos affects the expression of CTBP2 mRNAaffects expression 17297452
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of CTBP2 mRNAdecreases expression 20064835
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of CTBP2 mRNAdecreases expression 19150397
20018196
D016572 Cyclosporine Cyclosporine results in increased expression of CTBP2 mRNAincreases expression 20106945
D003994 Bucladesine Bucladesine affects the localization of CTBP2 proteinaffects localization 18184656
D003994 Bucladesine Bucladesine promotes the reaction [CTBP1 protein binds to CTBP2 protein]affects binding|increases reaction 18184656
D004040 Dietary Carbohydrates Dietary Carbohydrates results in increased expression of CTBP2 mRNAincreases expression 17490981
D004041 Dietary Fats Dietary Fats results in increased expression of CTBP2 mRNAincreases expression 18042831
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of CTBP2 mRNAincreases expression 17606305
D005472 Fluorouracil CTBP2 protein affects the susceptibility to [Fluorouracil co-treated with irinotecan analog]affects cotreatment|affects response to substance 18927307
D005472 Fluorouracil [Fluorouracil co-treated with irinotecan] results in decreased expression of CTBP2 mRNAaffects cotreatment|decreases expression 16391804
D019833 Genistein Genistein results in increased expression of CTBP2 mRNAincreases expression 15256057
D017313 Fenretinide Fenretinide results in decreased expression of CTBP2 mRNAdecreases expression 16467112
C051890 irinotecan CTBP2 protein affects the susceptibility to [Fluorouracil co-treated with irinotecan analog]affects cotreatment|affects response to substance 18927307
C051890 irinotecan [Fluorouracil co-treated with irinotecan] results in decreased expression of CTBP2 mRNAaffects cotreatment|decreases expression 16391804
C051890 irinotecan irinotecan analog results in decreased expression of CTBP2 mRNAdecreases expression 18927307
D009151 Mustard Gas Mustard Gas affects the expression of CTBP2 mRNAaffects expression 15651846
C058346 N-(4-methoxyphenyl)retinamide N-(4-methoxyphenyl)retinamide results in decreased expression of CTBP2 mRNAdecreases expression 16467112
C041786 palm oil palm oil results in increased expression of CTBP2 mRNAincreases expression 18042831
D019289 Pyruvic Acid Pyruvic Acid affects the localization of CTBP2 proteinaffects localization 18184656
D019289 Pyruvic Acid Pyruvic Acid inhibits the reaction [CTBP1 protein binds to CTBP2 protein]affects binding|decreases reaction 18184656
D019289 Pyruvic Acid Pyruvic Acid promotes the reaction [CTBP2 protein binds to CYP17A1 promoter]affects binding|increases reaction 18184656
D012643 Selenium [Selenium co-treated with Vitamin E] results in decreased expression of CTBP2 mRNAaffects cotreatment|decreases expression 19244175
D012643 Selenium Selenium results in decreased expression of CTBP2 mRNAdecreases expression 19244175
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of CTBP2 mRNAdecreases expression 17101203
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of CTBP2 mRNAincreases expression 19465110
D014212 Tretinoin Tretinoin results in decreased expression of CTBP2 mRNAdecreases expression 16604517
D014810 Vitamin E [Selenium co-treated with Vitamin E] results in decreased expression of CTBP2 mRNAaffects cotreatment|decreases expression 19244175
D014810 Vitamin E Vitamin E results in decreased expression of CTBP2 mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.7211752688 15322242 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.4318287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8117505938
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 13.2120127859 20464547
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 13.2114692618
MESH:D000230 Adenocarcinoma Fenretinide 13.2110697514
MESH:D000230 Adenocarcinoma Fluorouracil 13.2117638652
MESH:D000230 Adenocarcinoma Genistein 13.2111473722
MESH:D000236 Adenoma Benzo(a)pyrene 2.586695378
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.2516835633
MESH:D000505 Alopecia Tretinoin 3.5115955085
MESH:D000740 Anemia Fluorouracil 8.2916511603 15504547 17963324
MESH:D000740 Anemia Tetrachlorodibenzodioxin 8.2911748828
MESH:D000799 Angioedema Acetaminophen 3.7110982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.9419183758
MESH:D001161 Arteriosclerosis Dietary Fats 9.4715238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.4711256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.9415885639
MESH:D001169 Arthritis, Experimental Tretinoin 6.9416412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2316292516
MESH:D001249 Asthma Mustard Gas 4.8510378619
MESH:D001249 Asthma Tretinoin 4.8516456186
MESH:D050197 Atherosclerosis Asbestos 4.1418795166
MESH:D001321 Autistic Disorder Acetaminophen 1.4318445737
MESH:D001471 Barrett Esophagus Tretinoin 4.2716935849
MESH:D001768 Blister Mustard Gas 5.0319167455
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.5412125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 8.5416206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6815746008
MESH:D001932 Brain Neoplasms Fenretinide 4.2316187019
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 3.6920146248 17474063
MESH:D001943 Breast Neoplasms Dietary Fats 3.6920435547
MESH:D001943 Breast Neoplasms Fenretinide 3.6916601279
MESH:D001943 Breast Neoplasms Fluorouracil 3.6918608205 16557594 19217205 16110121 16595493 18357371 15136595
MESH:D001943 Breast Neoplasms Genistein 3.6917200150 16873071 16541309
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 3.6920435547
MESH:D001943 Breast Neoplasms Tretinoin 3.6916873071 16443354 16166294
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 5.0315286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.8517687719 10378619
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.4616813970
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.8016050911
MESH:D002276 Carcinoid Tumor Fluorouracil 4.5416051944
MESH:D002277 Carcinoma Fluorouracil 7.8417121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.8416835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.0316168501
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 8.663084413
MESH:D006528 Carcinoma, Hepatocellular Fenretinide 8.6617159502 16270382
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 8.6617088986 16799960 16332177 17971768 17045692 18930000
MESH:D006528 Carcinoma, Hepatocellular Genistein 8.6616924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 8.661917145
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 2.9618695887
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 10.5220419170
MESH:D002294 Carcinoma, Squamous Cell Fenretinide 10.5216274795
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 10.5216280240 18986760 16757204 17066447
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 10.5216096774 16051514
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3018850075 18670907 16120746
MESH:D002318 Cardiovascular Diseases Genistein 3.2116332659
MESH:D002386 Cataract Acetaminophen 6.9710977129
MESH:D002386 Cataract Tretinoin 6.9717460283
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 6.2620889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 6.2612371664
MESH:D018290 Cervical Intraepithelial Neoplasia Fenretinide 12.5416154183
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 12.5416129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.0516835633
MESH:D002779 Cholestasis Cyclosporine 7.4519486331
MESH:D002779 Cholestasis Ethinyl Estradiol 7.4516105132 16919318 17681005 15861022 17110522 11677210 17333356
MESH:D002822 Choriocarcinoma Tretinoin 5.0316461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.5815340226 16354765 12621046 8697196 15668235
MESH:D002972 Cleft Palate Tretinoin 5.589407595
MESH:D003092 Colitis Selenium 9.0617936198
MESH:D003092 Colitis Tretinoin 9.0617035595
MESH:D003110 Colonic Neoplasms Fluorouracil 5.7717725105 15001691 17172411 16510598 16340194 18772588 17287894 17018589 17016597 17169374
MESH:D003110 Colonic Neoplasms Genistein 5.7717182828
MESH:D003110 Colonic Neoplasms irinotecan 5.7717287894 17725105
MESH:D015179 Colorectal Neoplasms Fenretinide 3.5517273769
MESH:D015179 Colorectal Neoplasms Fluorouracil 3.5518448328 14970324 16391804 17094418 16524972 15289873 17401013 18383874 16331619 17454858 16282729 18288408 18802399 18509181 20501625 17016601 17695437 17255274 15148649 16303861 18949393 17594712
MESH:D015179 Colorectal Neoplasms irinotecan 3.5516391804 17159606 17454858 18259882 16303861 15273666 18509181
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9517141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.6810048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 3.689142499 10589399 14991402 16925845 9664655 17551590 9125849 8800419 9211117 9224671
MESH:D019465 Craniofacial Abnormalities Vitamin E 3.6819769572
MESH:D007644 Darier Disease Fluorouracil 4.6616733453
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 4.2216647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.2217107852
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 5.9116109766 12594235 14725611 19739265 16177239 11529661 16781746 10663392 12958197 19164858 14986274 18713872 12705907 10915739 11834606 11743745 16227642 14550746 19085960 11739529 17906064 11287661 16081117 15619225 18071297 2444490 11461765 12540782 19416960 12153990 11421492 12392966 16393943 19923254 19370779 19420014 15968718 16485898 17522070 17562736 10774834
MESH:D056486 Drug-Induced Liver Injury Selenium 5.9115131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 5.9120420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.9719426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6611462148
MESH:D050171 Dyslipidemias Dietary Fats 3.3618367378
MESH:C538011 Eales disease Vitamin E 4.579068938
MESH:D004487 Edema Mustard Gas 6.459260866 11428647 11402378 11428631
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.4512711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 11.5115322242 16714409 18230668
MESH:D004489 Edema, Cardiac Tretinoin 11.5118230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.0612538720
MESH:D004714 Endometrial Hyperplasia Genistein 4.4616402032
MESH:D016889 Endometrial Neoplasms Genistein 7.2711473722
MESH:D016889 Endometrial Neoplasms Tretinoin 7.2716569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.9110568697 9294722
MESH:D004890 Erythema Mustard Gas 5.039357497
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.0320426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 7.0316530937
MESH:D004938 Esophageal Neoplasms Fluorouracil 7.0315173087 17638652 16337965 16481741 16785472
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.5111564622
MESH:D005124 Eye Abnormalities Tretinoin 8.5116938888 9664655
MESH:D005234 Fatty Liver Cyclosporine 12.3719224547
MESH:D005234 Fatty Liver Dietary Fats 12.3718296743 19004024 19551842 17967931
MESH:D005234 Fatty Liver Ethinyl Estradiol 12.3715345470
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3311858732
MESH:D005355 Fibrosis Cyclosporine 20.0612639820 12168785
MESH:D005355 Fibrosis Dietary Fats 20.0618296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 20.0620067830
MESH:D005355 Fibrosis Tretinoin 20.0617994277
MESH:D005756 Gastritis Acetaminophen 3.5516983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.098708960
MESH:D005909 Glioblastoma Fenretinide 11.5116187019
MESH:D005909 Glioblastoma Genistein 11.5116598420
MESH:D005909 Glioblastoma Tretinoin 11.5117312396
MESH:D005910 Glioma Fluorouracil 2.8216145905
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4710696789
MESH:D006258 Head and Neck Neoplasms Fluorouracil 7.5015102660 15162350 18337622
MESH:D006258 Head and Neck Neoplasms Tretinoin 7.5016096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.0316084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 15.4020471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 15.4011294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 15.4014991402 9664655
MESH:D006330 Heart Defects, Congenital Vitamin E 15.4016080930
MESH:D006333 Heart Failure Selenium 2.9917162251
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.2915720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2111000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.7612621046 16120746 15340226
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.6616490937 16863852
MESH:D019584 Hot Flashes Vitamin E 3.8414716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.9218606429 8697196 16354765 16959395 15340226
MESH:D006930 Hyperalgesia Acetaminophen 7.2816870215
MESH:D006930 Hyperalgesia Tretinoin 7.2816870215
MESH:D006937 Hypercholesterolemia Dietary Fats 3.4721332399
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.4416778211
MESH:D006949 Hyperlipidemias Dietary Fats 3.4921332399
MESH:D006973 Hypertension Cyclosporine 4.7810903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.7818670907 18850075
MESH:D007021 Hypospadias Ethinyl Estradiol 3.6816569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3412013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.4017937319
MESH:D007249 Inflammation Dietary Fats 7.9420412841
MESH:D007249 Inflammation Mustard Gas 7.9411428631 16001271 9357497 11428647 11402378 8975870 9260866 17524151 11428620
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 7.9412200463 12878042
MESH:D007251 Influenza, Human Selenium 10.5316624496
MESH:D007251 Influenza, Human Vitamin E 10.5316624496
MESH:D007333 Insulin Resistance Dietary Fats 3.0211836018 18457598
MESH:D007410 Intestinal Diseases Tretinoin 3.6417994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.5316580747
MESH:D007569 Jaw Abnormalities Tretinoin 9.5315992940 17551590
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.3115604871
MESH:D007674 Kidney Diseases Acetaminophen 9.5715629191 12587719
MESH:D007674 Kidney Diseases Cyclosporine 9.5718776723 10903974 8314463
MESH:D007674 Kidney Diseases Vitamin E 9.5712488133
MESH:D007676 Kidney Failure, Chronic Selenium 3.7616518626
MESH:D007680 Kidney Neoplasms Cyclosporine 7.0412371664
MESH:D007680 Kidney Neoplasms Fluorouracil 7.0416985049
MESH:D007938 Leukemia Genistein 6.2017468513 18980019
MESH:D007938 Leukemia Tretinoin 6.2017143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.5816482212 16932348 19285840
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0616294345 19850784 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.0719035177 16935935 9834237 19075265 16891316 12679006 17649720 17301526 17294898 17368321 16823087 15748426 17361223 16788101 17712046 16766008 17107899 19225113 17339181 19029980 19642359 16331271 16140955 17506722 17217047
MESH:D007972 Leukoplakia, Oral Fenretinide 5.9216707609
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.219224671
MESH:D008103 Liver Cirrhosis Dietary Fats 2.8118296743
MESH:D008106 Liver Cirrhosis, Experimental Genistein 4.8317823541
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.8312878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 4.8316248980 18397230
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 4.8316169303
MESH:D008107 Liver Diseases Acetaminophen 1.6019460945 16611625 19784758 12587719 12969438 16610002 19014921 11587558
MESH:D017114 Liver Failure, Acute Acetaminophen 3.1217185352 16871587
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 7.1120195826 21137059
MESH:D008113 Liver Neoplasms Fluorouracil 7.1117045692 18383874 15113037 16603448
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 7.1116984957
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 2.0312151625
MESH:D008171 Lung Diseases Mustard Gas 7.2518161513 18702808
MESH:D008171 Lung Diseases Vitamin E 7.2516863852
MESH:D008175 Lung Neoplasms Asbestos 8.3612111688
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 8.3620464547 20064080 18569708 18520028 18816296 20869020 20135361 6695378 17053015
MESH:D008175 Lung Neoplasms Fluorouracil 8.3615246190
MESH:D008175 Lung Neoplasms Mustard Gas 8.363148597 8781369
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 8.3611884234 19555203
MESH:D008175 Lung Neoplasms Vitamin E 8.3611062179
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.6615086387
MESH:D008325 Mammary Neoplasms, Experimental Fenretinide 9.6510697514
MESH:D008325 Mammary Neoplasms, Experimental Genistein 9.6512929590 14578162
MESH:D008325 Mammary Neoplasms, Experimental Selenium 9.6515318939
MESH:D008527 Medulloblastoma Tretinoin 2.7317453147
MESH:D008545 Melanoma Fenretinide 3.5616270382
MESH:D008545 Melanoma Tretinoin 3.5616752155
MESH:D008546 Melanoma, Experimental Acetaminophen 3.4419513568
MESH:D008591 Meningomyelocele Tretinoin 4.2916940565
MESH:D008654 Mesothelioma Asbestos 6.4918709470 16564556 18310086 16319530 16919927
MESH:D008654 Mesothelioma Selenium 6.4915107826
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.6616801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 13.8816381670
MESH:D009062 Mouth Neoplasms Fenretinide 13.8816274795
MESH:D009062 Mouth Neoplasms Fluorouracil 13.8818986760 16757204
MESH:D052016 Mucositis irinotecan 4.8817159606
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.0117596541
MESH:D009203 Myocardial Infarction Genistein 2.8017141266
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9112213967
MESH:D015428 Myocardial Reperfusion Injury Genistein 3.5617141266
MESH:D009362 Neoplasm Metastasis irinotecan 3.1218259882
MESH:D009369 Neoplasms Benzo(a)pyrene 11.3811141357
MESH:D009369 Neoplasms Fenretinide 11.3817353921 15958647
MESH:D009369 Neoplasms Fluorouracil 11.3818239605 16928823 18600527
MESH:D009369 Neoplasms Tretinoin 11.3816946489 16594593
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.3117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.1718481113 19348381
MESH:D009421 Nervous System Malformations Genistein 15.6416427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 15.6414600291
MESH:D009421 Nervous System Malformations Tretinoin 15.649125849
MESH:D009436 Neural Tube Defects Tretinoin 2.979142499
MESH:D009447 Neuroblastoma irinotecan 3.418761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.7618514411
MESH:D017599 Neuroectodermal Tumors irinotecan 4.608761367
MESH:D009472 Neuronal Ceroid-Lipofuscinoses Fenretinide 5.5516303764
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.3516436463
MESH:D009503 Neutropenia Mustard Gas 3.8516761898 7688884
MESH:D009765 Obesity Dietary Fats 2.2618674790 19632207 20132043 21332399 16723640 17217161 18457598 20518802 11836018
MESH:D010024 Osteoporosis Genistein 3.1719401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 3.9616169203
MESH:D010051 Ovarian Neoplasms Fenretinide 7.7916133793
MESH:D010051 Ovarian Neoplasms Genistein 7.7919005980
MESH:D010051 Ovarian Neoplasms Tretinoin 7.7916936753
MESH:D010146 Pain Acetaminophen 6.2316870215
MESH:D010146 Pain Tretinoin 6.2316870215
MESH:D010190 Pancreatic Neoplasms Fenretinide 8.4815580305
MESH:D010190 Pancreatic Neoplasms Fluorouracil 8.4816500647 16929163 15113037 19003803
MESH:D010190 Pancreatic Neoplasms Tretinoin 8.4815976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5611578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1212520081
MESH:D010954 Plasmacytoma Selenium 4.7615087411
MESH:D011041 Poisoning Mustard Gas 3.6715727166
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4318163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.1112371664
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.0611222880 11896295 11399792 11118676
MESH:D011471 Prostatic Neoplasms marker/mechanism 18264096
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 1.8917292933
MESH:D011471 Prostatic Neoplasms Fenretinide 1.8917024972
MESH:D011471 Prostatic Neoplasms Fluorouracil 1.8918626508 19082440
MESH:D011471 Prostatic Neoplasms Genistein 1.8916925846 15378649 15256057
MESH:D011471 Prostatic Neoplasms Vitamin E 1.8915084515
MESH:D011507 Proteinuria Tretinoin 3.4816636307
MESH:D011537 Pruritus Ethinyl Estradiol 9.0915861022 16919318
MESH:D011537 Pruritus Mustard Gas 9.0918058305
MESH:D011565 Psoriasis Cyclosporine 2.1816882103
MESH:D011625 Pterygium Tretinoin 4.6616723453
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.8817620002 17894541 10334151 17266442 17720292
MESH:D012004 Rectal Neoplasms Fluorouracil 3.9015538739 16160472 18722050 18286688
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7118990726
MESH:D012162 Retinal Degeneration Fenretinide 4.3016303925
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.9816283617 16116481
MESH:D012871 Skin Diseases Mustard Gas 4.9115451306 12880345 16961503
MESH:D012871 Skin Diseases Vitamin E 4.9118709164
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 17.3119755658 10029692
MESH:D012878 Skin Neoplasms Fenretinide 17.3116467112
MESH:D012878 Skin Neoplasms N-(4-methoxyphenyl)retinamide 17.3116467112
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 17.3116192470
MESH:D012878 Skin Neoplasms Tretinoin 17.3116467112
MESH:D013088 Spermatocele Ethinyl Estradiol 3.8116709447
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 4.632093021 20155912
MESH:D013274 Stomach Neoplasms Fluorouracil 4.6315786421 17498489 17522103 18567086 17172411 16951190 19084572 16424979 19015929 18396642
MESH:D013274 Stomach Neoplasms irinotecan 4.6315723263
MESH:D013274 Stomach Neoplasms Tretinoin 4.6317261132
MESH:D020521 Stroke Vitamin E 3.4116517955
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5011994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0415669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.7712697716
MESH:D013964 Thyroid Neoplasms Tretinoin 2.9316026305 17045167
MESH:D014062 Tongue Neoplasms Fluorouracil 9.4416280240
MESH:D014062 Tongue Neoplasms Tretinoin 9.4416051514
MESH:D014376 Tuberculosis Tretinoin 3.1516040207
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 5.1817053015
MESH:D001749 Urinary Bladder Neoplasms Fenretinide 5.1816720286
MESH:D014581 Urticaria Acetaminophen 2.8510982225
MESH:D002583 Uterine Cervical Neoplasms Fenretinide 15.2916154183
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 15.2916803524
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 15.2916129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.1714692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.4816752155
MESH:D014605 Uveitis Cyclosporine 3.851336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4712125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4214671159 15869587
MESH:D014820 Vitiligo Tretinoin 3.9316761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1215886252
MESH:D015430 Weight Gain Dietary Fats 3.6216723640
MESH:D009396 Wilms Tumor Tretinoin 3.8516287080
MESH:D014985 Xerophthalmia Cyclosporine 4.3117120751
Pathway ID Pathway Name
KEGG:05220 Chronic myeloid leukemia
KEGG:04330 Notch signaling pathway
KEGG:05200 Pathways in cancer
KEGG:04310 Wnt signaling pathway
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA26996
    • No data
    Releated disease ID Related disease Name
    PA445425Prostatic Neoplasms
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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