AutismKB 2.0

Annotation Detail for CNIH3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CNIH3 ( CNIH-3,FLJ38993 )
Gene Full Name: cornichon homolog 3 (Drosophila)
Band: 1q42.12
Quick LinksEntrez ID:149111; OMIM: NA; Uniprot ID:CNIH3_HUMAN; ENSEMBL ID: ENSG00000143786; HGNC ID: 26802
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000638 Amiodarone Amiodarone results in increased expression of CNIH3 mRNAincreases expression 19774075
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of CNIH3 mRNAdecreases expression 20064835
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of CNIH3 mRNAaffects expression 20382639
D004958 Estradiol [Progesterone co-treated with Estradiol] results in decreased expression of CNIH3 mRNAaffects cotreatment|decreases expression 17404688
D011374 Progesterone [Progesterone co-treated with Estradiol] results in decreased expression of CNIH3 mRNAaffects cotreatment|decreases expression 17404688
D011374 Progesterone Progesterone results in decreased expression of CNIH3 mRNAdecreases expression 17404688
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.5220127859 20464547
MESH:D000230 Adenocarcinoma Estradiol 4.5211473722
MESH:D000236 Adenoma Benzo(a)pyrene 2.846695378
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.5619183758
MESH:D001145 Arrhythmias, Cardiac Amiodarone 4.1520041841 18218290 18057881
MESH:D001281 Atrial Fibrillation Amiodarone 4.1618651412 19698954
MESH:D001778 Blood Coagulation Disorders Amiodarone 4.2719483382
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.9517868700
MESH:D001930 Brain Injuries Progesterone 4.7415380490 15665606 15845082
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.8917474063 20146248
MESH:D001943 Breast Neoplasms Estradiol 1.8917289903 12948864 17261762 16675129 19861407 18497071 14630087 17018787
MESH:D001943 Breast Neoplasms Progesterone 1.8917614352 15562024 16175315
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 5.0016111702
MESH:D006528 Carcinoma, Hepatocellular Estradiol 1.7916924424
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1320419170
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.9919225199 15710769
MESH:D002341 Carotid Artery Thrombosis Amiodarone 5.6218974383
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.4420889678
MESH:D002471 Cell Transformation, Neoplastic Estradiol 7.4418566989
MESH:D003928 Diabetic Nephropathies Estradiol 3.7419279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.9817187935
MESH:D056486 Drug-Induced Liver Injury Amiodarone 2.4615265979 18218290
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 4.2217692515
MESH:D016889 Endometrial Neoplasms Estradiol 3.2019148513 18566989 11473722
MESH:D004715 Endometriosis Progesterone 4.1116134523
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.5920426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.5916530937
MESH:D005234 Fatty Liver Amiodarone 3.8914986274
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8220471113
MESH:D006529 Hepatomegaly Amiodarone 4.2315265979
MESH:D006558 Herpes Genitalis Estradiol 5.6415709030
MESH:D019584 Hot Flashes Estradiol 4.3617088409
MESH:D006937 Hypercholesterolemia Amiodarone 4.259751232 8137927
MESH:D007037 Hypothyroidism Amiodarone 5.0017991464 18020914
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.8915869954
MESH:D007249 Inflammation Progesterone 2.7515869954
MESH:D007333 Insulin Resistance Estradiol 3.1816393666 16627594
MESH:D007674 Kidney Diseases Estradiol 2.7615618244
MESH:D007680 Kidney Neoplasms Estradiol 3.2815610895
MESH:D008064 Lipidoses Amiodarone 3.7615342952 17567588
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 1.6814659978 14716833
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 2.1420195826 21137059
MESH:D008133 Long QT Syndrome Amiodarone 3.8511989578 15350150 17391786
MESH:D008171 Lung Diseases Amiodarone 3.6012587719
MESH:D017563 Lung Diseases, Interstitial Amiodarone 5.0918516814
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 1.5720464547 20064080 17053015 20135361 18520028 6695378 18569708 20869020 18816296
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 6.7717203775 11408345 11807958 16891317
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 6.7717203775 11408345
MESH:D020149 Manganese Poisoning Estradiol 5.0919453300
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.4616381670
MESH:D009181 Mycoses Amiodarone 5.5112754197 17974566
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.5516810080
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3111141357
MESH:D009389 Neovascularization, Pathologic Estradiol 4.2717289903
MESH:D009421 Nervous System Malformations Estradiol 4.0916427766 11399458
MESH:D010051 Ovarian Neoplasms Estradiol 5.1719401270
MESH:D010051 Ovarian Neoplasms Progesterone 5.1717393432 16525653
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 4.2620887781
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.0317292933
MESH:D011471 Prostatic Neoplasms Estradiol 3.0316740699
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.9612832656 11597910 12490602
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.9518045962
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 5.6218724381
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.5110029692 19755658
MESH:D013119 Spinal Cord Injuries Progesterone 4.8215862959 16503802
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.562093021 20155912
MESH:D013276 Stomach Ulcer Amiodarone 3.6818087811
MESH:D013610 Tachycardia Amiodarone 4.7311238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.6319225199
MESH:D013959 Thyroid Diseases Amiodarone 5.3719731979
MESH:D013971 Thyrotoxicosis Amiodarone 5.3418020914 19584973
MESH:D013978 Tibial Fractures Estradiol 5.3019048282
MESH:D016171 Torsades de Pointes Amiodarone 4.7317467628 11989578
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.2917053015
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved