Annotation Detail for PDIK1L
Basic Information
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| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D003010 |
Clorgyline |
Clorgyline results in increased expression of PDIK1L mRNA | increases expression | 19691856
|
| C023036 |
perfluorooctanoic acid |
perfluorooctanoic acid results in increased expression of PDIK1L mRNA | increases expression | 17560707
|
| C006253 |
pirinixic acid |
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of PDIK1L mRNA | affects binding|decreases expression|increases activity | 19710929
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.64 | 18653653 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
4.22 | 16434500 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.63 | 19483382 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
3.15 | 19176532 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.59 | 18249437 |
| MESH:D004487 |
Edema |
|
perfluorooctanoic acid |
8.62 | 12083418 17259670 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
8.62 | 12083418 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
3.25 | 19236843 20131406 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.78 | 20558911 |
| MESH:D006529 |
Hepatomegaly |
|
perfluorooctanoic acid |
10.97 | 3609246 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
10.97 | 16221962 18467677 19772884 19176532 |
| MESH:D006930 |
Hyperalgesia |
|
perfluorooctanoic acid |
4.21 | 12083418 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.63 | 20558911 |
| MESH:D007249 |
Inflammation |
|
perfluorooctanoic acid |
3.25 | 12083418 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.90 | 16306350 |
| MESH:D007984 |
Leydig Cell Tumor |
|
perfluorooctanoic acid |
5.97 | 8812269 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
| MESH:D008113 |
Liver Neoplasms |
|
perfluorooctanoic acid |
5.13 | 14757943 18709148 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
5.13 | 16377806 20007298 15890375 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
4.16 | 16239165 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.29 | 19151258 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.29 | 16411023 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.12 | 17405874 |
| MESH:D052556 |
Niemann-Pick Disease, Type C |
|
perfluorooctanoic acid |
5.61 | 9802331 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
1.89 | 20558911 |
| MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
perfluorooctanoic acid |
5.14 | 17132714 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Clorgyline |
4.22 | 19691856 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.56 | 19058328 |
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