Annotation Detail for AIFM3
Basic Information
Top
| Gene Symbol: | AIFM3 ( AIFL,FLJ30473,FLJ45137 ) |
|---|
| Gene Full Name: | apoptosis-inducing factor, mitochondrion-associated, 3 |
|---|
| Band: | 22q11.21 |
|---|
| Quick Links | Entrez ID:150209; OMIM: NA; Uniprot ID:AIFM3_HUMAN; ENSEMBL ID: ENSG00000183773; HGNC ID: 26398 |
|---|
| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C548651 |
2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester |
2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of AIFM3 mRNA | decreases expression | 19933214
|
| C006780 |
bisphenol A |
bisphenol A inhibits the reaction [Triiodothyronine results in decreased expression of AIFM3 mRNA] | decreases expression|decreases reaction | 19228888
|
| D010634 |
Phenobarbital |
NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of AIFM3 mRNA] | affects reaction|decreases expression | 19482888
|
| D010634 |
Phenobarbital |
Phenobarbital results in decreased expression of AIFM3 mRNA | decreases expression | 19482888
|
| C031280 |
pyrazole |
pyrazole results in decreased expression of AIFM3 mRNA | decreases expression | 17945193
|
| D014284 |
Triiodothyronine |
bisphenol A inhibits the reaction [Triiodothyronine results in decreased expression of AIFM3 mRNA] | decreases expression|decreases reaction | 19228888
|
| D014284 |
Triiodothyronine |
Triiodothyronine results in decreased expression of AIFM3 mRNA | decreases expression | 19228888
|
| D014284 |
Triiodothyronine |
Triiodothyronine results in increased expression of AIFM3 mRNA | increases expression | 17403546
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
Phenobarbital |
3.98 | 6195326 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
Phenobarbital |
4.51 | 17620307 |
| MESH:D001862 |
Bone Resorption |
|
bisphenol A |
4.24 | 11985600 |
| MESH:D001943 |
Breast Neoplasms |
|
bisphenol A |
2.43 | 17123778 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Phenobarbital |
1.94 | 1701930 20007298 20935162 17173139 6705139 |
| MESH:D002278 |
Carcinoma in Situ |
|
bisphenol A |
5.53 | 17123778 |
| MESH:D002493 |
Central Nervous System Diseases |
|
Phenobarbital |
4.74 | 4080065 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
pyrazole |
3.09 | 12499123 |
| MESH:D004421 |
Dystonia |
|
Phenobarbital |
4.41 | 1851702 |
| MESH:D004831 |
Epilepsies, Myoclonic |
|
Phenobarbital |
4.59 | 3659116 |
| MESH:D004828 |
Epilepsies, Partial |
|
Phenobarbital |
4.48 | 11558140 3922381 |
| MESH:D004827 |
Epilepsy |
|
Phenobarbital |
3.04 | 20417680 |
| MESH:D004832 |
Epilepsy, Absence |
|
Phenobarbital |
3.87 | 6401628 |
| MESH:D017029 |
Epilepsy, Complex Partial |
|
Phenobarbital |
4.74 | 7750514 |
| MESH:D004830 |
Epilepsy, Tonic-Clonic |
|
Phenobarbital |
4.56 | 3659116 |
| MESH:D006529 |
Hepatomegaly |
|
Phenobarbital |
3.97 | 16109766 |
| MESH:D007333 |
Insulin Resistance |
|
bisphenol A |
3.50 | 16393666 |
| MESH:D008103 |
Liver Cirrhosis |
|
Phenobarbital |
3.07 | 21047994 |
| MESH:D008107 |
Liver Diseases |
|
Phenobarbital |
2.23 | 19363144 |
| MESH:D008113 |
Liver Neoplasms |
|
Phenobarbital |
2.41 | 21047994 15975961 19482888 19073162 19812893 8742319 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
Phenobarbital |
2.90 | 2563599 17172636 6150874 1399818 18308698 |
| MESH:D020191 |
Myoclonic Epilepsies, Progressive |
|
Phenobarbital |
5.02 | 17484760 |
| MESH:D009421 |
Nervous System Malformations |
|
bisphenol A |
4.41 | 16427766 11399458 |
| MESH:D010018 |
Osteomalacia |
|
Phenobarbital |
4.90 | 17016548 |
| MESH:D010049 |
Ovarian Diseases |
|
bisphenol A |
5.53 | 11985600 |
| MESH:D010190 |
Pancreatic Neoplasms |
|
Phenobarbital |
2.59 | 16965848 |
| MESH:D011230 |
Precancerous Conditions |
|
Phenobarbital |
3.95 | 2563599 |
| MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
bisphenol A |
4.49 | 10548101 |
| MESH:D019048 |
Prostatic Intraepithelial Neoplasia |
|
bisphenol A |
4.58 | 20887781 |
| MESH:D011471 |
Prostatic Neoplasms |
|
bisphenol A |
3.35 | 16740699 |
| MESH:D019310 |
Pseudolymphoma |
|
Phenobarbital |
5.11 | 12752131 |
| MESH:D011629 |
Puberty, Precocious |
|
bisphenol A |
5.33 | 10548101 |
| MESH:D012640 |
Seizures |
|
Phenobarbital |
2.92 | 3137016 4039156 11442880 16876388 |
| MESH:D003294 |
Seizures, Febrile |
|
Phenobarbital |
5.36 | 6407741 |
| MESH:D019966 |
Substance-Related Disorders |
|
bisphenol A |
4.52 | 16045194 16684133 |
| MESH:D013733 |
Testicular Diseases |
|
pyrazole |
5.36 | 6499806 |
| MESH:D013964 |
Thyroid Neoplasms |
|
Phenobarbital |
3.32 | 1399818 |
| MESH:D014591 |
Uterine Diseases |
|
bisphenol A |
5.62 | 14652134 |
Related Pathway Information