AutismKB 2.0

Annotation Detail for DNAJB7


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:DNAJB7 ( DJ5,HSC3,MGC138340 )
Gene Full Name: DnaJ (Hsp40) homolog, subfamily B, member 7
Band: 22q13.2
Quick LinksEntrez ID:150353; OMIM: 611336; Uniprot ID:DNJB7_HUMAN; ENSEMBL ID: ENSG00000172404; HGNC ID: 24986
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of DNAJB7 mRNAdecreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of DNAJB7 mRNAaffects expression 17562736
D000638 Amiodarone Amiodarone results in increased expression of DNAJB7 mRNAincreases expression 19774075
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.983712494
MESH:D000799 Angioedema Acetaminophen 4.7110982225
MESH:D001145 Arrhythmias, Cardiac Amiodarone 4.2520041841 18218290 18057881
MESH:D001281 Atrial Fibrillation Amiodarone 4.2318651412 19698954
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.891440618 11289319
MESH:D001778 Blood Coagulation Disorders Amiodarone 4.3819483382
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 2.973581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 2.973084413
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.847296757
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 3.0119225199 15710769
MESH:D002341 Carotid Artery Thrombosis Amiodarone 5.8318974383
MESH:D002386 Cataract Acetaminophen 2.8110977129
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 3.057505956
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 3.479022650 19486331
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 3.4411906362 14531868 2524372 18759878 11298694 8156756 8970840 12868966
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 4.023621924 2952479
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 6.839328219 7440962 6679447 1440618 18648102 18692083 16192314 18289764 6482804 11289319 9653073 9022650 8291058
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.8311529661 16081117 16393943 14725611 12392966 19739265 17562736 16781746 16485898 15968718 19370779 19085960 10663392 10915739 19420014 14986274 18713872 19923254 10774834 19164858 12153990 17906064 12594235 11834606 19416960 15619225 11743745 17522070 11739529 11287661 14550746 2444490 18071297 11421492 11461765 12705907 12540782 12958197 16177239 16109766 16227642
MESH:D056486 Drug-Induced Liver Injury Amiodarone 6.8318218290 15265979
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.9619426721
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.193581430
MESH:D005234 Fatty Liver Amiodarone 4.0014986274
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.896705139
MESH:D005756 Gastritis Acetaminophen 4.5416983495
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.577505956
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 4.106705139
MESH:D006529 Hepatomegaly Amiodarone 4.4015265979
MESH:D006930 Hyperalgesia Acetaminophen 3.0616870215
MESH:D006937 Hypercholesterolemia Amiodarone 4.368137927 9751232
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.5915034207
MESH:D007037 Hypothyroidism Amiodarone 5.1717991464 18020914
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.899022650 8074119
MESH:D007674 Kidney Diseases Acetaminophen 2.4212587719 15629191
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 3.356582329
MESH:D008064 Lipidoses Amiodarone 3.8215342952 17567588
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.449327722 15034207
MESH:D008107 Liver Diseases Acetaminophen 1.7112587719 12969438 16610002 16611625 11587558 19784758 19460945 19014921
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6817185352 16871587
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 2.783712494 6587162 598648 1399818
MESH:D008133 Long QT Syndrome Amiodarone 3.9215350150 11989578 17391786
MESH:D008171 Lung Diseases Amiodarone 3.6512587719
MESH:D017563 Lung Diseases, Interstitial Amiodarone 5.3418516814
MESH:D008546 Melanoma, Experimental Acetaminophen 4.2219513568
MESH:D009181 Mycoses Amiodarone 5.7712754197 17974566
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.613581430
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 3.186679447
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2618514411
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.874026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.893988306
MESH:D010146 Pain Acetaminophen 2.7716870215
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 4.137296757
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 5.346228378
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.9812832656 12490602 11597910
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.703692021
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 5.8318724381
MESH:D013276 Stomach Ulcer Amiodarone 3.7918087811
MESH:D013610 Tachycardia Amiodarone 4.8711238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.7719225199
MESH:D013959 Thyroid Diseases Amiodarone 5.6219731979
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 3.226587162 6582329 3712494 1399818 7505956
MESH:D013971 Thyrotoxicosis Amiodarone 5.5118020914 19584973
MESH:D016171 Torsades de Pointes Amiodarone 4.9317467628 11989578
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 2.418074119
MESH:D014581 Urticaria Acetaminophen 3.5010982225
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved