AutismKB 2.0

Annotation Detail for CTSB


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Basic Information Top
Gene Symbol:CTSB ( APPS,CPSB )
Gene Full Name: cathepsin B
Band: 8p23.1
Quick LinksEntrez ID:1508; OMIM: 116810; Uniprot ID:CATB_HUMAN; ENSEMBL ID: ENSG00000164733; HGNC ID: 2527
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04142Lysosome
hsa04612Antigen processing and presentation
No data
No data
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1736Protozoan infection
1904Diabetes mellitus
1934Cancer
2134Amyotrophic lateral sclerosis
2231Arthritis
Desease Name
colorectal cancer
CANCER
IMMUNE
pancreatitis, tropical calcific
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C422565 13beta-methyl 19-nor-steroid 13beta-methyl 19-nor-steroid inhibits the reaction [IFNE protein inhibits the reaction [Progesterone results in increased expression of CTSB mRNA]]decreases reaction|increases expression 16099855
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the localization of and results in increased activity of CTSB proteinaffects localization|increases activity 12663669
C023035 3,4,5,3',4'-pentachlorobiphenyl 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CTSB mRNAdecreases expression 16291828
D000082 Acetaminophen Acetaminophen affects the expression of CTSB mRNAaffects expression 17562736
D000452 Aldrin Aldrin results in decreased activity of CTSB proteindecreases activity 8406551
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CTSB mRNAaffects expression 16483693
C435690 anilofos anilofos results in decreased activity of CTSB proteindecreases activity 8406551
C004984 apocarotenal apocarotenal results in decreased expression of CTSB mRNAdecreases expression 17034753
D019207 beta Carotene beta Carotene results in decreased expression of CTSB mRNAdecreases expression 17034753
C054409 butachlor butachlor results in decreased activity of CTSB proteindecreases activity 8406551
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of CTSB mRNAincreases expression 15336504
C400541 CA 074 methyl ester CA 074 methyl ester results in decreased activity of CTSB proteindecreases activity 12663669
D002166 Camptothecin CTSB protein results in increased cleavage of [Camptothecin analog binds to ALB protein]affects binding|increases cleavage 17378599
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of CTSB mRNAdecreases expression 17484886
D002713 Chlorine [Ozone co-treated with Chlorine] results in decreased expression of CTSB mRNAaffects cotreatment|decreases expression 18636392
C004656 chloroacetaldehyde chloroacetaldehyde results in decreased activity of CTSB proteindecreases activity 17035713
C019304 ciprofibrate ciprofibrate results in increased expression of CTSB mRNAincreases expression 12771043
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CTSB mRNAaffects cotreatment|affects expression 17602206
D003042 Cocaine Cocaine affects the expression of CTSB mRNAaffects expression 15681117
D016572 Cyclosporine Cyclosporine results in decreased activity of CTSB proteindecreases activity 10914799
D004041 Dietary Fats Dietary Fats results in decreased expression of CTSB mRNAdecreases expression 18042831
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of CTSB mRNAincreases expression 12771043
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CTSB mRNAaffects cotreatment|affects expression 17602206
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of CTSB mRNAincreases expression 15289156
D002117 Calcitriol Calcitriol results in increased expression of CTSB mRNAincreases expression 15951637
16847355
D004137 Dinitrochlorobenzene Dinitrochlorobenzene results in increased expression of CTSB mRNAincreases expression 16314067
D004178 Diquat Diquat affects the expression of CTSB mRNAaffects expression 16488489
D004317 Doxorubicin CTSB protein results in increased cleavage of [Doxorubicin analog binds to ALB protein]affects binding|increases cleavage 17378599
D004317 Doxorubicin Doxorubicin affects the expression of CTSB mRNAaffects expression 16705698
D004317 Doxorubicin Doxorubicin results in increased expression of CTSB mRNAincreases expression 19001878
D004317 Doxorubicin PARP1 protein promotes the reaction [Doxorubicin results in increased expression of CTSB mRNA]increases expression|increases reaction 19001878
D004726 Endosulfan Endosulfan results in decreased activity of CTSB proteindecreases activity 8406551
D004726 Endosulfan Endosulfan affects the expression of CTSB mRNAaffects expression 16786705
D004726 Endosulfan Endosulfan affects the expression of CTSB proteinaffects expression 16786705
D004958 Estradiol Estradiol results in increased expression of CTSB mRNAincreases expression 11509743
15289156
D000431 Ethanol Ethanol results in increased expression of CTSB mRNAincreases expression 7738427
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of CTSB mRNAdecreases expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of CTSB mRNAincreases expression 12655037
16140622
17557909
C082360 fipronil fipronil affects the expression of CTSB mRNAaffects expression 16786705
C082360 fipronil fipronil affects the expression of CTSB proteinaffects expression 16786705
D005419 Flavonoids Flavonoids results in decreased expression of CTSB mRNAdecreases expression 18035473
D005485 Flutamide Flutamide results in decreased expression of CTSB mRNAdecreases expression 11509743
C056933 fumonisin B1 fumonisin B1 results in increased expression of CTSB mRNAincreases expression 16221962
C043055 gallium arsenide gallium arsenide results in increased activity of CTSB proteinincreases activity 12583989
C043055 gallium arsenide gallium arsenide results in increased expression of CTSB mRNAincreases expression 12583989
D019833 Genistein Genistein results in increased expression of CTSB mRNAincreases expression 15289156
C010972 glycolaldehyde glycolaldehyde results in decreased activity of CTSB proteindecreases activity 16671891
D006037 Glyoxal Glyoxal results in decreased activity of CTSB proteindecreases activity 16671891
D007213 Indomethacin Indomethacin inhibits the reaction [CTSB protein results in increased degradation of MBP protein]decreases reaction|increases degradation 11071371
D007213 Indomethacin Indomethacin results in decreased activity of CTSB proteindecreases activity 11071371
C028904 isoproturon isoproturon results in decreased activity of CTSB proteindecreases activity 8406551
D007657 Ketone Bodies Ketone Bodies results in increased expression of CTSB mRNAincreases expression 16807920
C032854 leupeptin leupeptin inhibits the reaction [CTSB protein results in increased degradation of NEFL protein]decreases reaction|increases degradation 11071371
D001556 Lindane Lindane results in decreased activity of CTSB proteindecreases activity 8406551
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of CTSB mRNAincreases expression 19339665
D008070 Lipopolysaccharides methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of CTSB mRNA]increases expression|increases reaction 19339665
D008294 Malathion Malathion results in decreased activity of CTSB proteindecreases activity 8406551
C008435 methyldithiocarbamate methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of CTSB mRNA]increases expression|increases reaction 19339665
D008743 Methyl Parathion Methyl Parathion results in decreased activity of CTSB proteindecreases activity 8406551
D015741 Metribolone Metribolone results in decreased expression of CTSB proteindecreases expression 17152098
C029938 nickel sulfate nickel sulfate results in increased expression of CTSB mRNAincreases expression 16314067
D010126 Ozone [Ozone co-treated with Chlorine] results in decreased expression of CTSB mRNAaffects cotreatment|decreases expression 18636392
C041786 palm oil palm oil results in decreased expression of CTSB mRNAdecreases expression 18042831
D010269 Paraquat Paraquat results in decreased expression of CTSB mRNAdecreases expression 16797015
D010615 Phenacetin Phenacetin results in increased expression of CTSB mRNAincreases expression 17698508
C030299 phenylhydrazine phenylhydrazine results in increased expression of CTSB mRNAincreases expression 17698508
D010672 Phenytoin Phenytoin results in decreased activity of CTSB proteindecreases activity 10914799
D010672 Phenytoin Phenytoin results in increased expression of CTSB mRNAincreases expression 14741686
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of CTSB mRNAaffects binding|decreases expression|increases activity 19710929
D028321 Plant Preparations Plant Preparations affects the expression of CTSB mRNAaffects expression 16046712
D011374 Progesterone 13beta-methyl 19-nor-steroid inhibits the reaction [IFNE protein inhibits the reaction [Progesterone results in increased expression of CTSB mRNA]]decreases reaction|increases expression 16099855
D011374 Progesterone IFNE protein inhibits the reaction [Progesterone results in increased expression of CTSB mRNA]decreases reaction|increases expression 16099855
D011374 Progesterone Progesterone results in increased expression of CTSB mRNAincreases expression 16099855
D011765 Pyruvaldehyde Pyruvaldehyde results in decreased activity of CTSB proteindecreases activity 16671891
D020849 Raloxifene Raloxifene affects the expression of CTSB mRNAaffects expression 16079270
C009166 retinol acetate retinol acetate results in increased expression of CTSB mRNAincreases expression 16772331
D012643 Selenium Selenium results in increased expression of CTSB mRNAincreases expression 19244175
D013467 Sulindac Sulindac inhibits the reaction [CDKN1A protein results in increased expression of CTSB mRNA]decreases reaction|increases expression 15190207
D013629 Tamoxifen Tamoxifen affects the expression of CTSB mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of CTSB mRNAincreases expression 16267337
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of CTSB mRNAincreases expression 15644576
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of CTSB mRNAdecreases expression 16291828
D013853 Thioacetamide Thioacetamide results in increased expression of CTSB mRNAincreases expression 16297948
D014028 Tobacco Smoke Pollution Tobacco Smoke Pollution results in decreased expression of CTSB mRNAdecreases expression 15289447
C088658 zoledronic acid zoledronic acid results in decreased expression of CTSB proteindecreases expression 16475674
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Sulindac 10.7014745880
MESH:D000008 Abdominal Neoplasms Tamoxifen 10.7014745880
MESH:D000014 Abnormalities, Drug-Induced Ethanol 10.4718926900 17676605
MESH:D000014 Abnormalities, Drug-Induced Phenytoin 10.473425630 9118846 9677735 8986270 10563481 6195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 10.4711752688 15322242 14514962
MESH:D000138 Acidosis Ammonium Chloride 8.2018287403
MESH:D000138 Acidosis Ethanol 8.2011192467
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.2417505938
MESH:D058186 Acute Kidney Injury Sulindac 7.207897758
MESH:D058186 Acute Kidney Injury zoledronic acid 7.2019715164
MESH:D055371 Acute Lung Injury Chlorine 16.6220601635
MESH:D055371 Acute Lung Injury Lipopolysaccharides 16.6211850527 18653653
MESH:D055371 Acute Lung Injury nickel sulfate 16.6212718980 11954676 16100012 19131640
MESH:D055371 Acute Lung Injury pirinixic acid 16.6218653653
MESH:D000210 Acute-Phase Reaction zoledronic acid 4.8020200999
MESH:D000230 Adenocarcinoma Doxorubicin 14.0417418594
MESH:D000230 Adenocarcinoma Estradiol 14.0411473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 14.0414692618
MESH:D000230 Adenocarcinoma Genistein 14.0411473722
MESH:D000230 Adenocarcinoma Indomethacin 14.0416537180
MESH:D000230 Adenocarcinoma Sulindac 14.0411910360
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Tobacco Smoke Pollution 4.8315814487
MESH:D000236 Adenoma Diethylnitrosamine 8.8210737359 6695378
MESH:D000236 Adenoma Indomethacin 8.8211497255
MESH:D000236 Adenoma Sulindac 8.8210223192
MESH:D018248 Adenoma, Liver Cell 3,4,5,3',4'-pentachlorobiphenyl 19.3316628245
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 19.3316434500 17620307 19061943 19052882 18056438 17162532
MESH:D018248 Adenoma, Liver Cell pirinixic acid 19.3316434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 19.3316835633
MESH:D011125 Adenomatous Polyposis Coli Sulindac 4.0012394442 11874996 15623613 16460482 19003578 11535846 17611924
MESH:D000382 Agricultural Workers' Diseases Lindane 10.7212661182
MESH:D000382 Agricultural Workers' Diseases Malathion 10.7217119214 11874814
MESH:D000382 Agricultural Workers' Diseases Paraquat 10.7211874814
MESH:D000419 Albuminuria Doxorubicin 9.2921441931
MESH:D000419 Albuminuria Raloxifene 9.2917308373 17451421
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.6215451039 15451040
MESH:D016301 Alveolar Bone Loss Indomethacin 4.6717225004
MESH:D000544 Alzheimer Disease Indomethacin 5.4715579461 17627676
MESH:D000544 Alzheimer Disease Ozone 5.4715513908
MESH:D000544 Alzheimer Disease Raloxifene 5.4715800139
MESH:D000686 Amyloidosis Diethylstilbestrol 3.8315469931
MESH:D000740 Anemia Phenacetin 11.672444515
MESH:D000740 Anemia phenylhydrazine 11.672444515
MESH:D000740 Anemia Tetrachlorodibenzodioxin 11.6711748828
MESH:D000743 Anemia, Hemolytic Phenacetin 9.0017082564 1949026 17698508
MESH:D000743 Anemia, Hemolytic phenylhydrazine 9.0017082564 17084956 17698508
MESH:D000799 Angioedema Acetaminophen 3.1510982225
MESH:D000853 Anophthalmos Ethanol 4.1515513904
MESH:D001008 Anxiety Disorders Ethanol 3.4511141031
MESH:D001014 Aortic Aneurysm Indomethacin 4.1910231640
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 4.2010388637
MESH:D001161 Arteriosclerosis Dietary Fats 7.6915238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 7.6911256880
MESH:D018771 Arthralgia Indomethacin 4.472160914
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.2115885639
MESH:D001172 Arthritis, Rheumatoid Indomethacin 6.2911248219
MESH:D001172 Arthritis, Rheumatoid Ozone 6.2915570426
MESH:D001172 Arthritis, Rheumatoid Tobacco Smoke Pollution 6.2919898480
MESH:D001249 Asthma Ozone 2.3916373670 17854713
MESH:D050197 Atherosclerosis Phenytoin 3.4915136057
MESH:D001321 Autistic Disorder Acetaminophen 1.5318445737
MESH:D001477 Bartter Syndrome Indomethacin 4.3110684365
MESH:D001778 Blood Coagulation Disorders pirinixic acid 11.7819483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 11.7812125929
MESH:D001778 Blood Coagulation Disorders Thioacetamide 11.7819483382
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.0915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.2915746008
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.0014601052
MESH:D001859 Bone Neoplasms zoledronic acid 4.3217312309 16121404 16778634 11697798 15867366 19442620
MESH:D001862 Bone Resorption zoledronic acid 4.0911869084 8053405 15845617 18496637 18404659 16769263
MESH:D001913 Bowen's Disease Sulindac 4.6611207687
MESH:D001929 Brain Edema Indomethacin 4.3311481608
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.6417868700
MESH:D001930 Brain Injuries Progesterone 8.7415845082 15380490 15665606
MESH:D001930 Brain Injuries Raloxifene 8.7416580743
MESH:D002545 Brain Ischemia beta Carotene 8.3916157235
MESH:D002545 Brain Ischemia Indomethacin 8.3912524144
MESH:D001932 Brain Neoplasms Doxorubicin 3.2117150277
MESH:D001943 Breast Neoplasms Calcitriol 15.4711237771
MESH:D001943 Breast Neoplasms Dietary Fats 15.4720435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 15.4717474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 15.4717129689 15324884
MESH:D001943 Breast Neoplasms Doxorubicin 15.4716264153 16595493 16096432 15567936 18695136 15634643 15136595 15939500 19526202 17426702 16826403 16322301 11325840 16935488 18382427 15994142 18234424 18628466 17983394 15692762 17369602 16115903 15993339 15668708
MESH:D001943 Breast Neoplasms Estradiol 15.4712948864 18497071 17018787 19861407 16675129 17289903 17261762 14630087
MESH:D001943 Breast Neoplasms Genistein 15.4716873071 16541309 17200150
MESH:D001943 Breast Neoplasms Indomethacin 15.4717401462
MESH:D001943 Breast Neoplasms Lindane 15.4714688026
MESH:D001943 Breast Neoplasms Malathion 15.4712762645
MESH:D001943 Breast Neoplasms Plant Preparations 15.4717398067
MESH:D001943 Breast Neoplasms Progesterone 15.4715562024 16175315 17614352
MESH:D001943 Breast Neoplasms Raloxifene 15.4716912660 17440819 16837676 17595753 17049068 15758505 15775269 17893378 17242785 17952589 17261762 15572757
MESH:D001943 Breast Neoplasms Sulindac 15.4716642371
MESH:D001943 Breast Neoplasms Tamoxifen 15.4715668708 19289846 19115204 19142967 18629630 18855134 15565566 19066611 19189212 18997820 20390343 18984771 19288272 16818667 17261762 20065188 20135344 18425577 19084267 18351453 19155303 17242785 19189210 20005174 19011961 18821012 18815881 16202921 19200415 17440819 21152245 19059307 17893378 16873071 11161223 19410462 19221464 16273361 20544844 20859285 21138602 19103187 19244106 19487384 17049068
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 15.4720435547
MESH:D001943 Breast Neoplasms zoledronic acid 15.4716096432 18695136
MESH:D016535 Bronchial Hyperreactivity Ozone 3.1218315731 16777450 18417511 19059883 15516495 14754758 17626835
MESH:D002056 Burns Ethanol 9.1616374292
MESH:D002056 Burns Indomethacin 9.1610459503
MESH:D002100 Cachexia Indomethacin 10.1215625704 16537180 11239499 15141370
MESH:D002100 Cachexia Ozone 10.1216183385
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.7816111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.1116097048 16011737 16050911 16124888 16192424 15721981 18705752 16227642 10355542 3786805 15700767 15673190
MESH:D002276 Carcinoid Tumor Doxorubicin 4.1116051944
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.2516835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 3.8319066611
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 22.133084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 22.1318788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 22.1320514400 19394651 18788625 3581430 19919837 16807293 16878318 17978847 16935385 19335982 20214788 17761372 19052882 16288022 3084413 19519916 18506893 17173139 18210153 20084675 19539802 20935162 17055752 17428255 18393292 17138121 10672840 19171122 19701751 20512989 20727157 18971187 16328049 18665156 18978308 10737359 16779866 18056438 16698587 11831363 20007298 19107877 16502159 20524982 19418558 21159647 19822196 20101231 16830150 19208518 20432363 16540662 16569478 19383236 18785209 18691550 16681979 18494052 17162532
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 22.1315948411 16924424
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 22.1318059187 16234567 17876044 16023760
MESH:D006528 Carcinoma, Hepatocellular Estradiol 22.1316924424
MESH:D006528 Carcinoma, Hepatocellular Ethanol 22.1318788625 15763234 15289165
MESH:D006528 Carcinoma, Hepatocellular Genistein 22.1316924424
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 22.1316391822
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 22.1316924424
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 22.1317997003
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 4.0411053908
MESH:D018276 Carcinoma, Medullary Indomethacin 4.6614736730 18791128 11352223
MESH:D002289 Carcinoma, Non-Small-Cell Lung Tobacco Smoke Pollution 5.1411212258
MESH:D002289 Carcinoma, Non-Small-Cell Lung zoledronic acid 5.1419233551
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 8.801485588 16201981
MESH:D002292 Carcinoma, Renal Cell Indomethacin 8.8017341418
MESH:D002292 Carcinoma, Renal Cell zoledronic acid 8.8018507039
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 11.5811237771
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 11.586189445
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 11.5815482327 12636206
MESH:D002294 Carcinoma, Squamous Cell Plant Preparations 11.5817418620
MESH:D002294 Carcinoma, Squamous Cell Tobacco Smoke Pollution 11.5811212258
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 7.5017572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 7.5017572228
MESH:D006332 Cardiomegaly Ethanol 5.4319332462
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 5.4318670907 18850075 16120746
MESH:D009202 Cardiomyopathies Doxorubicin 3.0515505089 17519947 16731534 15476868 16364871 16455267 17351982 16242529 17308081 17924179 16278810 15792986 15811867 17382496 17329180 17974986 16952015 16612575 18627295 17007740 16269455 17131338 17928571 16109756 16651473
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.6617334414 16243910
MESH:D002318 Cardiovascular Diseases Genistein 9.4716332659
MESH:D002318 Cardiovascular Diseases Plant Preparations 9.4716862667
MESH:D002318 Cardiovascular Diseases Raloxifene 9.4715775269
MESH:D016893 Carotid Stenosis Plant Preparations 5.4515158307
MESH:D002386 Cataract Acetaminophen 2.1410977129
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 8.2612371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 8.267505956 2727394 17174075 21159647
MESH:D002471 Cell Transformation, Neoplastic Estradiol 8.2618566989
MESH:D002493 Central Nervous System Diseases Phenytoin 4.634080065
MESH:D018281 Cholangiocarcinoma 3,4,5,3',4'-pentachlorobiphenyl 18.3016628245
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 18.3019052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 18.3016835633
MESH:D018281 Cholangiocarcinoma Thioacetamide 18.3018291259
MESH:D002764 Cholecystitis Indomethacin 4.4711181007
MESH:D002779 Cholestasis Cyclosporine 10.2819486331
MESH:D002779 Cholestasis Ethinyl Estradiol 10.2817333356 16919318 15861022 11677210 17110522 16105132 17681005
MESH:D002779 Cholestasis pirinixic acid 10.2819176532
OMIM:601042 CHOREOATHETOSIS/SPASTICITY, EPISODIC Phenytoin 5.1811748493
MESH:D002971 Cleft Lip Ethanol 6.5915513904
MESH:D002971 Cleft Lip Phenytoin 6.592227380
MESH:D002972 Cleft Palate Ethanol 7.9815513904
MESH:D002972 Cleft Palate Phenytoin 7.983877104 10789828 6862529 2227380 1687470 6856622
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 7.9816354765 8697196 15668235 12621046 15340226
MESH:D019970 Cocaine-Related Disorders Cocaine 5.0319606084
MESH:D003072 Cognition Disorders Raloxifene 3.9515800139
MESH:D003092 Colitis Selenium 3.1217936198
MESH:D003093 Colitis, Ulcerative Dinitrochlorobenzene 3.5817373747 19159591
MESH:D003103 Coloboma Phenytoin 4.539212184
MESH:D003110 Colonic Neoplasms Genistein 4.9417182828
MESH:D003110 Colonic Neoplasms Indomethacin 4.9411260862 15936596 15963497 15637740 15625704 15786552
MESH:D003110 Colonic Neoplasms Sulindac 4.9412902858 12458338
MESH:D015179 Colorectal Neoplasms Doxorubicin 3.1318259882 18802399
MESH:D015179 Colorectal Neoplasms Indomethacin 3.1311197048 12606626 18059344 17054584
MESH:D015179 Colorectal Neoplasms Sulindac 3.1311197048 10666051 11076880 18059344
MESH:D000013 Congenital Abnormalities Phenytoin 7.4310627286
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 7.4314669216 17141729
MESH:D003324 Coronary Artery Disease Plant Preparations 3.7015158307
MESH:D018352 Coronavirus Infections Indomethacin 5.0217302372
MESH:D019465 Craniofacial Abnormalities 3,4,5,3',4'-pentachlorobiphenyl 4.6117686920
MESH:D019465 Craniofacial Abnormalities Ethanol 4.6119302082 15513904 15451039 11873399 11198716 10194807 15451040
MESH:D019465 Craniofacial Abnormalities Phenytoin 4.619212184 8986270 19952982
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 4.6110048152 15322242 20055451
MESH:D003456 Cryptorchidism Diethylstilbestrol 3.9012952375 16002989
MESH:D003490 Cyanosis Endosulfan 4.877900959
MESH:D003711 Demyelinating Diseases Tamoxifen 3.6919031437
MESH:D003865 Depressive Disorder, Major Raloxifene 3.5717474826
MESH:D017449 Dermatitis, Allergic Contact Dinitrochlorobenzene 5.5115491423
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 5.5116780908 11298694 16823706
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.0618249437
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 5.7620387270
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 5.7616647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 5.7617107852
MESH:D003928 Diabetic Nephropathies Estradiol 11.6319279558
MESH:D003928 Diabetic Nephropathies Raloxifene 11.6317308373 17451421 15920148
MESH:D003928 Diabetic Nephropathies Tamoxifen 11.6319279558
MESH:D003929 Diabetic Neuropathies Progesterone 3.8217187935
MESH:D003930 Diabetic Retinopathy Sulindac 4.5212861449 17621415
MESH:D003967 Diarrhea Indomethacin 3.167237001 7907874
OMIM:607208 DRAVET SYNDROME Phenytoin 4.7211748493
MESH:D003875 Drug Eruptions Phenytoin 4.8315024534
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 23.7515968718 16109766 10774834 11529661 16081117 17522070 16177239 14550746 12392966 11421492 19085960 11461765 19420014 12958197 19923254 11287661 2444490 16227642 11743745 16781746 16393943 19739265 12594235 10663392 16485898 11834606 15619225 10915739 19164858 17906064 17562736 12705907 12153990 14725611 12540782 19416960 18713872 18071297 19370779 14986274 11739529
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 23.7515968718 3786805 10915739 10092053 3732212 6623471 9327722 11566570 7120509 7179309 16177239 19336974 16227642 6884620 7440962 15998439 21278145 15027814 4309450 2869522 17522070 19085960
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 23.7519107877
MESH:D056486 Drug-Induced Liver Injury Diquat 23.7518164269 18445702
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 23.7517416283
MESH:D056486 Drug-Induced Liver Injury Ethanol 23.7511566570
MESH:D056486 Drug-Induced Liver Injury fumonisin B1 23.7516221962
MESH:D056486 Drug-Induced Liver Injury Selenium 23.7515131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 23.7520420201
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 23.7512963478
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.4019426721
MESH:D004362 Drug Toxicity Doxorubicin 10.8218602426
MESH:D004362 Drug Toxicity Plant Preparations 10.8211033412
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 10.8211462148
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 4.4616326151 17190690 16133044 18446180 12774134 18043480
MESH:D004381 Duodenal Ulcer Indomethacin 3.4917202747 11535926 11595431 17329845 17045617 11991626 11595415 10671773 16699067 17151854 17351913
MESH:D050171 Dyslipidemias Dietary Fats 2.9418367378
MESH:D004417 Dyspnea Chlorine 8.5420016425
MESH:D004417 Dyspnea Endosulfan 8.547900959 3388749
MESH:D004487 Edema Indomethacin 11.4716100529 8985016 7907874 7990266 19703484 8273558 10653021
MESH:D004487 Edema pirinixic acid 11.4712083418
MESH:D004487 Edema Raloxifene 11.4715860553
MESH:D004487 Edema Tetrachlorodibenzodioxin 11.4712711302 11000095
MESH:D004489 Edema, Cardiac 3,4,5,3',4'-pentachlorobiphenyl 10.1017686920
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.1016714409 15322242 18230668
MESH:D004646 Emphysema Endosulfan 5.857900959
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 27.3515138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 27.3512538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Phenytoin 27.3517654737
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 27.3517692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 27.3515845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 27.3519031437
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 9.6216402032
MESH:D004714 Endometrial Hyperplasia Genistein 9.6216402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 18.2616804899 15700306
MESH:D016889 Endometrial Neoplasms Doxorubicin 18.2617359293
MESH:D016889 Endometrial Neoplasms Estradiol 18.2618566989 11473722 19148513
MESH:D016889 Endometrial Neoplasms Genistein 18.2611473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 18.2619155303 16202921 20544844 17893378
MESH:D004715 Endometriosis Indomethacin 16.9415652904
MESH:D004715 Endometriosis Progesterone 16.9416134523
MESH:D004715 Endometriosis Sulindac 16.9415652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 16.949294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.4618037988
MESH:D019446 Endotoxemia Indomethacin 8.3818509659
MESH:D019446 Endotoxemia Lipopolysaccharides 8.3815821434 17637181 15328337
MESH:D004751 Enteritis Indomethacin 4.0510567023 16328016 17763956
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 4.3117980183
MESH:D004802 Eosinophilia Indomethacin 3.4011298111
MESH:D004816 Epidermal Necrolysis, Toxic Phenytoin 4.5420235791
MESH:D004820 Epidermolysis Bullosa Phenytoin 5.531399206 6251365
MESH:D004828 Epilepsies, Partial Phenytoin 4.2311558140 17116037
MESH:D004827 Epilepsy Phenytoin 3.54821787 20417680 11434505
MESH:D017029 Epilepsy, Complex Partial Phenytoin 4.637750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenytoin 4.383659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.4216302075
MESH:D004938 Esophageal Neoplasms Ethanol 8.5816704527
MESH:D004938 Esophageal Neoplasms Indomethacin 8.5811005569
MESH:D004938 Esophageal Neoplasms Plant Preparations 8.5816510608
MESH:D004938 Esophageal Neoplasms Sulindac 8.5812235107
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.4811564622
MESH:D005218 Fat Necrosis Thioacetamide 5.0216456712
MESH:D005234 Fatty Liver Carbon Tetrachloride 37.6912631006 61145 15959796 16239168 12795759 17595544 19224547 16045604
MESH:D005234 Fatty Liver Cyclosporine 37.6919224547
MESH:D005234 Fatty Liver Dietary Fats 37.6918296743 19004024 19551842 17967931
MESH:D005234 Fatty Liver Diethylnitrosamine 37.6920387270 21071580
MESH:D005234 Fatty Liver Ethanol 37.6916409862 18620774 19236843
MESH:D005234 Fatty Liver Ethinyl Estradiol 37.6915345470
MESH:D005234 Fatty Liver pirinixic acid 37.6920131406 19236843
MESH:D005234 Fatty Liver Raloxifene 37.6917473493
MESH:D005234 Fatty Liver Tamoxifen 37.6914986274 19224547
MESH:D005235 Fatty Liver, Alcoholic Ethanol 4.9617920746
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 6.6916513791 15751030 16611131 16002989 16534752
MESH:D052776 Female Urogenital Diseases Tamoxifen 6.6916709447
MESH:D005264 Femoral Fractures zoledronic acid 5.1416234978
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.6110194807 16946407 15513904 15451040
MESH:D005313 Fetal Death Phenytoin 8.5210627286
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 8.5211858732
MESH:D005334 Fever Indomethacin 7.3610431976 17627676 11852909
MESH:D005334 Fever Lipopolysaccharides 7.3611852909 9205823
MESH:D018221 Fibromatosis, Abdominal Sulindac 10.6814745880
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 10.6814745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 15.5919069698
MESH:D018222 Fibromatosis, Aggressive Sulindac 15.5919069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 15.5919069698
MESH:D005354 Fibrosarcoma Indomethacin 4.2110962813
MESH:D005355 Fibrosis Carbon Tetrachloride 20.7118705752
MESH:D005355 Fibrosis Cyclosporine 20.7112639820 12168785
MESH:D005355 Fibrosis Dietary Fats 20.7118296743
MESH:D005355 Fibrosis Indomethacin 20.7117994277
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 20.7120067830
MESH:D005499 Folliculitis Indomethacin 4.4711298111
MESH:D005739 Gas Poisoning Chlorine 4.3120016425
MESH:D005756 Gastritis Acetaminophen 21.6516983495
MESH:D005756 Gastritis Diquat 21.6515046732
MESH:D005756 Gastritis Ethanol 21.6515046732
MESH:D005756 Gastritis Indomethacin 21.6515046732
MESH:D005764 Gastroesophageal Reflux Sulindac 4.3611910360
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 4.2616452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 10.638708960
MESH:D005885 Gingival Hyperplasia Phenytoin 10.639029455
MESH:D019214 Gingival Overgrowth Phenytoin 5.5314659971 16390469
MESH:D005909 Glioblastoma Doxorubicin 9.2217150277
MESH:D005909 Glioblastoma Genistein 9.2216598420
MESH:D005909 Glioblastoma Indomethacin 9.2212870263
MESH:D005910 Glioma Indomethacin 2.9116487511 18371953
MESH:D005911 Gliosis Paraquat 4.4611124998
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 3.7211849393
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.8910696789
MESH:D006073 Gout Indomethacin 4.6611248219
MESH:D006258 Head and Neck Neoplasms Doxorubicin 6.4115692506
MESH:D006258 Head and Neck Neoplasms Indomethacin 6.4115482327
MESH:D006330 Heart Defects, Congenital 3,4,5,3',4'-pentachlorobiphenyl 5.6520471113 17686920
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 5.6511294989 10048152
MESH:D006331 Heart Diseases Doxorubicin 6.1716707910 18006777 18674790 17875725 17888722 16879835 12587719 16495754 16330681 16244372 16144979 14766674 16244371
MESH:D006331 Heart Diseases Raloxifene 6.1711110106
MESH:D006333 Heart Failure Doxorubicin 9.1317481944
MESH:D006333 Heart Failure pirinixic acid 9.1320558911
MESH:D006333 Heart Failure Selenium 9.1317162251
MESH:D006394 Hemangiosarcoma chloroacetaldehyde 7.9210626228
MESH:D006394 Hemangiosarcoma Doxorubicin 7.9215692506
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.7315720958
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 3.7816366002
MESH:D006470 Hemorrhage Endosulfan 8.397900959
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 8.3911000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 8.8815633222
MESH:D006501 Hepatic Encephalopathy Thioacetamide 8.8818665440 17276928 15929193
MESH:D006505 Hepatitis Carbon Tetrachloride 7.3219110552 19900420
MESH:D006505 Hepatitis Thioacetamide 7.3216456712
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.0315135802
MESH:D006529 Hepatomegaly fumonisin B1 10.6516221962
MESH:D006529 Hepatomegaly pirinixic acid 10.6518467677 19176532 19772884 16221962
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 10.6516120746 15340226 12621046
MESH:D006558 Herpes Genitalis Estradiol 4.3315709030
MESH:D015658 HIV Infections beta Carotene 3.6516960176
MESH:D006689 Hodgkin Disease Doxorubicin 2.8517606976 15147373 18501091
MESH:D019584 Hot Flashes Estradiol 3.0617088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.358697196 18606429 16959395 15340226 16354765
MESH:D006930 Hyperalgesia Acetaminophen 14.1916870215
MESH:D006930 Hyperalgesia Ethanol 14.1918783367
MESH:D006930 Hyperalgesia Indomethacin 14.1912727271
MESH:D006930 Hyperalgesia zoledronic acid 14.1916769263
MESH:D034321 Hyperamylasemia Indomethacin 5.0217883296
MESH:D017588 Hyperandrogenism Flutamide 4.7615356085
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.8516899240
MESH:D006934 Hypercalcemia zoledronic acid 4.4319622757 18089816
MESH:D006937 Hypercholesterolemia Dietary Fats 2.9821332399
MESH:D006940 Hyperemia Indomethacin 4.3212524144
MESH:D006943 Hyperglycemia pirinixic acid 2.5820558911
MESH:D020138 Hyperhomocysteinemia Phenytoin 4.0810459572
MESH:D006949 Hyperlipidemias Dietary Fats 7.2421332399
MESH:D006949 Hyperlipidemias Indomethacin 7.2417546600
MESH:D006965 Hyperplasia Diethylstilbestrol 3.7714722030 12960047
MESH:D006973 Hypertension Cyclosporine 6.7210903974
MESH:D006973 Hypertension Raloxifene 6.7217577099 15787275
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 6.7218670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.4215338365
MESH:D006996 Hypocalcemia zoledronic acid 5.4912669777
MESH:D007021 Hypospadias Diethylstilbestrol 9.0216002989
MESH:D007021 Hypospadias Ethinyl Estradiol 9.0216945680 16569931
MESH:D007077 Ileal Diseases Indomethacin 4.3318306037 10574470
MESH:D007079 Ileitis Indomethacin 4.6610651667 10647630 16133968
MESH:D007235 Infant, Premature, Diseases Indomethacin 4.6716133044
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 3.7315869954
MESH:D007246 Infertility Diethylstilbestrol 3.7015036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.8312013081
MESH:D007248 Infertility, Male Diquat 12.174850670
MESH:D007248 Infertility, Male Endosulfan 12.178588293 9432128
MESH:D007248 Infertility, Male Ethinyl Estradiol 12.1717937319
MESH:D007248 Infertility, Male Paraquat 12.174850670
MESH:D007249 Inflammation Dietary Fats 28.8620412841
MESH:D007249 Inflammation Diethylnitrosamine 28.8618785209
MESH:D007249 Inflammation Flavonoids 28.8617296493
MESH:D007249 Inflammation Indomethacin 28.867812673 3291741 12568917
MESH:D007249 Inflammation Lipopolysaccharides 28.8617963957 9205823 17255318 12878042 17237260
MESH:D007249 Inflammation Progesterone 28.8615869954
MESH:D007249 Inflammation Sulindac 28.863291741
MESH:D007249 Inflammation Tamoxifen 28.8619457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 28.8612878042 12200463
MESH:D007249 Inflammation Tobacco Smoke Pollution 28.8618590791
MESH:D007251 Influenza, Human Selenium 3.5016624496
MESH:D007333 Insulin Resistance Dietary Fats 9.5018457598 11836018
MESH:D007333 Insulin Resistance Estradiol 9.5016627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 9.5016306350
MESH:D007410 Intestinal Diseases Indomethacin 3.6618236018 15831440 17994277 10210152 11686837 11713966 11855677 17329856 15610444
MESH:D007414 Intestinal Neoplasms Sulindac 4.0312584176 12628509 10223192 10213222 12663524 12351151
MESH:D007417 Intestinal Polyps Sulindac 4.3511245490 12394442
MESH:D019586 Intracranial Hypertension Indomethacin 4.6715241188
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 3.9917255318
MESH:D007569 Jaw Abnormalities Ethanol 8.0615513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 8.0616580747
MESH:D007579 Jejunal Diseases Indomethacin 4.3310574470 18306037 16133968
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.7415604871
MESH:D007674 Kidney Diseases Acetaminophen 18.2115629191 12587719
MESH:D007674 Kidney Diseases chloroacetaldehyde 18.2116221203
MESH:D007674 Kidney Diseases Cyclosporine 18.2110903974 8314463 18776723
MESH:D007674 Kidney Diseases Doxorubicin 18.2116775033 15699352 15369732
MESH:D007674 Kidney Diseases Estradiol 18.2115618244
MESH:D007674 Kidney Diseases Indomethacin 18.2117190690
MESH:D007676 Kidney Failure, Chronic Doxorubicin 7.9316707910
MESH:D007676 Kidney Failure, Chronic Selenium 7.9316518626
MESH:D007680 Kidney Neoplasms Cyclosporine 13.1212371664
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 13.1216762066 15003126 14681315
MESH:D007680 Kidney Neoplasms Estradiol 13.1215610895
MESH:D007680 Kidney Neoplasms Tamoxifen 13.1218625569
MESH:D007859 Learning Disorders Diethylstilbestrol 12.4317184923
MESH:D007859 Learning Disorders Endosulfan 12.438157075
MESH:D007859 Learning Disorders Ethanol 12.4315451040
MESH:D007889 Leiomyoma Raloxifene 3.8616973256
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.3410320625 12228301 11703811
MESH:D007938 Leukemia 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 5.4912970779
MESH:D007938 Leukemia Genistein 5.4918980019 17468513
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.4616085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell zoledronic acid 4.1518089816
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 3.4015631656 10785260 16572323
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 2.4918360721
MESH:D007964 Leukocytosis Indomethacin 4.6716537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.0217980183
MESH:D007970 Leukopenia Lipopolysaccharides 4.0115821434
MESH:D017880 Limb Deformities, Congenital Ethanol 3.3017676605
MESH:D008064 Lipidoses Tamoxifen 2.6517567588 15342952
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.0211479899
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 12.2917334410 11408273 17174718 16239168 11903743 16943688 21278145 17157831 16221502
MESH:D008103 Liver Cirrhosis Dietary Fats 12.2918296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 12.2918522880 18407596 19638242 20032147 18665156
MESH:D008103 Liver Cirrhosis Ethanol 12.2915289165
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.4118295389
MESH:D008105 Liver Cirrhosis, Biliary Sulindac 3.7612468960
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 20.1515057751 13678700 18317297 18481824 15650968 16033810 15370692 18205269 15893842 17761835 16116963 18418968 14620537 10355542 18006644 17721639 17944888 18429990 18054572 16027843 12649538 14716833 18472094 18156304 20821823 16192424 17565644 12586293 17869086 12741479 18705752 12445421 16136751 15876570 17698563 12632512 12445418 15052691 14724832 16097048 11481614 15818738 14512876 18420326 12389079 18395095 17481882 18263696 15925388 15362042 14716496 18187930 16248980 15959796 18210741 17640975 12666154 17766677 17823541 17708605 15931870 15996030 18395914 15123356 17805973 17631135 16015684 12667390 15338365 12609069 18412020 16011737 17714472 17976157 18472332 17525996 18251166 18279442 17922224 18339082 14748882 12958196 18376398 17900296 16638106 18166357 17557913 18277467 12632514 12898905 15730626 12546737 15673190
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 20.1516439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 20.1514659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 20.1518166357
MESH:D008106 Liver Cirrhosis, Experimental Genistein 20.1517823541
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 20.1518194892
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 20.1512878042
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 20.1515474484
MESH:D008106 Liver Cirrhosis, Experimental Plant Preparations 20.1517724770
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 20.1518564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 20.1512878042
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 20.1512557150 11172339 12891558 18458672 17292413 15316131 18615449 16248980 16097051 17629604 14739098 18295389 15362042 15474484 18263696 18031379 12085344 18032466 16343077 15095483 17050028 18380797 17127702 15158331 17355460 15716488 10677585 15288473 16489207 12679928 18606216 18416461 18395095 15334695 16511523 15075984 15465738 12531686 12175628 11682029 15288472 11481614 16098781 16126171 15078482
MESH:D008107 Liver Diseases Acetaminophen 15.6819014921 12587719 12969438 11587558 19460945 16611625 19784758 16610002
MESH:D008107 Liver Diseases Carbon Tetrachloride 15.6816246199 15720792 16964402 17285989 15830285
MESH:D008107 Liver Diseases Diethylnitrosamine 15.6817034775
MESH:D008107 Liver Diseases Lindane 15.681715830
MESH:D008107 Liver Diseases Phenytoin 15.6814986274
MESH:D008107 Liver Diseases Sulindac 15.6816867024 14986274
MESH:D008107 Liver Diseases Thioacetamide 15.6818374380 15158337 16337175
MESH:D008108 Liver Diseases, Alcoholic Ethanol 3.9817347304 17207112
MESH:D017093 Liver Failure Carbon Tetrachloride 3.4915123358
MESH:D017114 Liver Failure, Acute Acetaminophen 12.7716871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 12.7716899240 14706259
MESH:D017114 Liver Failure, Acute Thioacetamide 12.7712479984 15313186 17276928 15633222
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 20.2919294768
MESH:D008113 Liver Neoplasms ciprofibrate 20.2912771043
MESH:D008113 Liver Neoplasms Clofibric Acid 20.2917602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 20.2919996281 10737359 18978307 19812893 19551842 12112319 21047994 20492335 20583210 12771043 20501860 19256749 20101389 19833225 19255062 20137499 21167192 20452335 2422723 20405173 21071580 9163691 19073162 19294768 19427195 19638242 20118626 18754104 19850985 18977376 15175105 19690152 19090486 18644402 18648771 21278145 20434301 19426721 16942905 19499222 19642983 15885732 2862719 19254457
MESH:D008113 Liver Neoplasms Diethylstilbestrol 20.2915890375 16712894
MESH:D008113 Liver Neoplasms pirinixic acid 20.2915890375 16377806 20007298
MESH:D008113 Liver Neoplasms Tamoxifen 20.2916684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 20.2916984957
MESH:D008114 Liver Neoplasms, Experimental beta Carotene 17.3917113696
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 17.3915583823 12014681
MESH:D008114 Liver Neoplasms, Experimental chloroacetaldehyde 17.3910626228
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 17.3918775883 16267830 18079962 19539802 18544905 19009564 18093689 18308698 17942915 2563599 21159647 17174075 3124819 17854601 19004024 19519916 18164116 18253720 19126423 18282651 9362446 16842330
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 17.3917085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 17.3912151625
MESH:D008171 Lung Diseases Ozone 2.8919066396 8266340
MESH:D055370 Lung Injury Lipopolysaccharides 7.0321114838
MESH:D055370 Lung Injury Ozone 7.0320417186
MESH:D008175 Lung Neoplasms beta Carotene 12.8216401635
MESH:D008175 Lung Neoplasms Diethylnitrosamine 12.8220970405 20512841 6695378 21163286
MESH:D008175 Lung Neoplasms Doxorubicin 12.826189445 17418594
MESH:D008175 Lung Neoplasms Indomethacin 12.8211053908 11497255 16537180
MESH:D008175 Lung Neoplasms Ozone 12.828597069 7614698
MESH:D008175 Lung Neoplasms Sulindac 12.8219359593 15713900
MESH:D008175 Lung Neoplasms Tamoxifen 12.8218625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 12.8219555203 11884234
MESH:D008175 Lung Neoplasms Tobacco Smoke Pollution 12.8211091918 12111688 16288123 3440675
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.4615166399
MESH:D008223 Lymphoma Diethylstilbestrol 6.0415700306
MESH:D008223 Lymphoma Doxorubicin 6.0416098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.2217654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 3.9015621674
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 4.8216002989
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.0819428831
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 21.2615458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 21.2611807958 11408345 16891317 17203775
MESH:D008325 Mammary Neoplasms, Experimental Genistein 21.2612929590 14578162
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 21.2611408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Selenium 21.2615318939
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 21.2619196722 11731420 16827153 14580682 19196723
MESH:D008325 Mammary Neoplasms, Experimental zoledronic acid 21.2617312309
MESH:D020149 Manganese Poisoning Estradiol 10.3319453300
MESH:D020149 Manganese Poisoning Tamoxifen 10.3319453300
MESH:D008545 Melanoma Dinitrochlorobenzene 5.9612202904 17334785
MESH:D008545 Melanoma Doxorubicin 5.9616827129
MESH:D008545 Melanoma Sulindac 5.9616642371
MESH:D008545 Melanoma Tamoxifen 5.9612393984 19393235
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.5015990972
MESH:D008546 Melanoma, Experimental Acetaminophen 2.9019513568
MESH:D008569 Memory Disorders Ethanol 3.5418411066 15451040
MESH:D008607 Mental Retardation Phenytoin 3.399212184
MESH:D008654 Mesothelioma Doxorubicin 8.4017638057
MESH:D008654 Mesothelioma Selenium 8.4015107826
MESH:D008654 Mesothelioma zoledronic acid 8.4016675582
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.0916801185
MESH:D008679 Metaplasia Ozone 4.4110496685
MESH:D008708 Methemoglobinemia Phenacetin 4.321949026 16296465 3537620 4834387
MESH:D008881 Migraine Disorders Indomethacin 3.1711903285
MESH:D008924 Mite Infestations fipronil 6.2716884176
MESH:D028361 Mitochondrial Diseases Doxorubicin 3.8815792986
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 4.8515863610
MESH:D009062 Mouth Neoplasms Indomethacin 11.5912636206
MESH:D009062 Mouth Neoplasms Plant Preparations 11.5917418620
MESH:D009062 Mouth Neoplasms Tobacco Smoke Pollution 11.5915006635
MESH:D052016 Mucositis Doxorubicin 4.1017415656
MESH:D009101 Multiple Myeloma Raloxifene 6.0716497877
MESH:D009101 Multiple Myeloma zoledronic acid 6.0718089719 16996129 19621390
MESH:D009135 Muscular Diseases pirinixic acid 2.8416239165
MESH:D009203 Myocardial Infarction Cocaine 10.7818072171
MESH:D009203 Myocardial Infarction Doxorubicin 10.7819429709 15857846
MESH:D009203 Myocardial Infarction Genistein 10.7817141266
MESH:D009203 Myocardial Infarction pirinixic acid 10.7819151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.4612213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 11.0216810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 11.0217141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 11.0216411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenytoin 4.8417484760
MESH:D009224 Myotonia Congenita Phenytoin 4.731896199
MESH:D009232 Myxoma Raloxifene 4.8516343187
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 14.413581430 9029167
MESH:D009362 Neoplasm Metastasis Doxorubicin 14.4118259882
MESH:D009362 Neoplasm Metastasis Indomethacin 14.4111239499 16537180 11053908
MESH:D009362 Neoplasm Metastasis Tamoxifen 14.4119393235
MESH:D009362 Neoplasm Metastasis zoledronic acid 14.4117312309 19139120 15867366
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.2419410462
MESH:D009369 Neoplasms beta Carotene 8.7717051425
MESH:D009369 Neoplasms Diethylstilbestrol 8.7715313581
MESH:D009369 Neoplasms Lindane 8.7716818664 12807735
MESH:D009369 Neoplasms pirinixic acid 8.7717405874
MESH:D009374 Neoplasms, Experimental Indomethacin 3.4810663608 15625704
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.3019189210 19200415 19196722
MESH:D009389 Neovascularization, Pathologic Estradiol 3.0517289903
MESH:D009401 Nephrosis Doxorubicin 4.1016636307 16899518
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.7417954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 7.3418481113 19348381
MESH:D009404 Nephrotic Syndrome Doxorubicin 7.3416889571 15640375
MESH:D009410 Nerve Degeneration Paraquat 3.1816893418
MESH:D009421 Nervous System Malformations Diethylstilbestrol 18.1311399458
MESH:D009421 Nervous System Malformations Estradiol 18.1311399458 16427766
MESH:D009421 Nervous System Malformations Genistein 18.1316427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 18.1314600291
MESH:D009436 Neural Tube Defects Phenytoin 3.669118846
MESH:D009447 Neuroblastoma Doxorubicin 2.8715555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 15.4618514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 15.4620387270
MESH:D019636 Neurodegenerative Diseases Indomethacin 15.4612349958
MESH:D019636 Neurodegenerative Diseases Sulindac 15.4616850258 17266991
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.4220387270
MESH:D020258 Neurotoxicity Syndromes Malathion 7.4115081274
MESH:D020258 Neurotoxicity Syndromes Methyl Parathion 7.4119784758
MESH:D009765 Obesity Dietary Fats 3.6717217161 11836018 18674790 18457598 21332399 16723640 19632207 20518802 20132043
MESH:D009765 Obesity pirinixic acid 3.6720558911
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.476374098
MESH:D010003 Osteoarthritis Indomethacin 3.227009135
MESH:D010014 Osteolysis zoledronic acid 4.6815867366
MESH:D010018 Osteomalacia Phenytoin 4.7317016548
MESH:D010024 Osteoporosis Genistein 9.3619401787
MESH:D010024 Osteoporosis Raloxifene 9.3617882678 19059307 15775268
MESH:D010024 Osteoporosis zoledronic acid 9.3617882678
MESH:D015663 Osteoporosis, Postmenopausal Genistein 8.0316169203
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 8.0317823083 15758505 15579764 17893378
MESH:D012516 Osteosarcoma Doxorubicin 3.5515930896
MESH:D010051 Ovarian Neoplasms 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 9.0516211241
MESH:D010051 Ovarian Neoplasms Estradiol 9.0519401270
MESH:D010051 Ovarian Neoplasms Genistein 9.0519005980
MESH:D010051 Ovarian Neoplasms Progesterone 9.0517393432 16525653
MESH:D010146 Pain Acetaminophen 15.2816870215
MESH:D010146 Pain Indomethacin 15.2813679232 17627676 3291741 17440234
MESH:D010146 Pain Phenytoin 15.2815215642
MESH:D010146 Pain Sulindac 15.283291741
MESH:D010146 Pain zoledronic acid 15.2816475674
MESH:D010149 Pain, Postoperative Indomethacin 3.9818702446 12538197
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 7.0016540662
MESH:D010190 Pancreatic Neoplasms Ethanol 7.0012384795
MESH:D010190 Pancreatic Neoplasms Sulindac 7.0011504793 16820089
MESH:D010195 Pancreatitis Indomethacin 3.3015028970 17883296
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.0511578682
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.0216537180
MESH:D010300 Parkinson Disease Paraquat 2.5211445065 16510128 12911755 11181820 11124998 16140633 15451049 15824117
MESH:D010302 Parkinson Disease, Secondary Paraquat 3.7616190885
MESH:D020734 Parkinsonian Disorders Indomethacin 3.5212349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.0211903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.5512520081
MESH:D010437 Peptic Ulcer Indomethacin 4.4611148446
MESH:D010518 Periodontitis Indomethacin 4.2217225004
MESH:D010538 Peritonitis Ozone 3.4716369182
MESH:D003557 Phyllodes Tumor Doxorubicin 4.4617983394
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.4714722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.0016977796 15687265
MESH:D010954 Plasmacytoma Selenium 4.1915087411
MESH:D010997 Pleural Neoplasms Doxorubicin 4.4617638057
MESH:D011014 Pneumonia Lipopolysaccharides 14.6211605937 12224865
MESH:D011014 Pneumonia Ozone 14.6218929643 18381685 18007984
MESH:D011014 Pneumonia Paraquat 14.6212504350
MESH:D011041 Poisoning Methyl Parathion 4.4117603234
MESH:D011085 Polycystic Ovary Syndrome Flutamide 4.3915356085
MESH:D017689 Polydactyly Phenytoin 4.459212184
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.9118163543
MESH:D011230 Precancerous Conditions Cyclosporine 6.9912371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 6.992563599
MESH:D047928 Premature Birth Indomethacin 4.4617000239
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 7.3017184923
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 7.3011118676 11896295 11222880 11399792
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.0915572423
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.2620887781
MESH:D011471 Prostatic Neoplasms marker/mechanism 19503093
MESH:D011471 Prostatic Neoplasms Calcitriol 3.0715754350 16289102 16644109 18247401 12479363
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 3.0717136230 15846301 15046698
MESH:D011471 Prostatic Neoplasms Doxorubicin 3.0718437689 15897917 16729912 16868541 16888761 15749863
MESH:D011471 Prostatic Neoplasms Estradiol 3.0716740699
MESH:D011471 Prostatic Neoplasms Flutamide 3.073169114
MESH:D011471 Prostatic Neoplasms Genistein 3.0715256057 15378649 16925846
MESH:D011471 Prostatic Neoplasms Lindane 3.0714688026 12661182
MESH:D011471 Prostatic Neoplasms Raloxifene 3.0715731164 16220300 16536755
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.0715067354
MESH:D011471 Prostatic Neoplasms zoledronic acid 3.0712438248 19103299
MESH:D011507 Proteinuria Indomethacin 3.5311849393
MESH:D011537 Pruritus Ethinyl Estradiol 2.6415861022 16919318
MESH:D019310 Pseudolymphoma Phenytoin 4.8412752131 1419762 8603615
MESH:D011565 Psoriasis Cyclosporine 1.9416882103
MESH:D011618 Psychotic Disorders Cocaine 4.3016134406
MESH:D011658 Pulmonary Fibrosis Paraquat 2.6117997886 16324872
MESH:D011693 Purpura Raloxifene 4.8515770314
MESH:D051437 Renal Insufficiency Doxorubicin 3.5617922066
MESH:D015427 Reperfusion Injury pirinixic acid 2.0119058328
MESH:D012120 Respiration Disorders Chlorine 4.5118579056
MESH:D012128 Respiratory Distress Syndrome, Adult Paraquat 3.2811700416
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.2510835634
MESH:D012135 Respiratory Sounds Malathion 12.5117119214 11874814
MESH:D012135 Respiratory Sounds Paraquat 12.5111874814
MESH:D012135 Respiratory Sounds Tobacco Smoke Pollution 12.5118410779
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.1818990726
MESH:D012140 Respiratory Tract Diseases Malathion 4.8317119214
MESH:D012162 Retinal Degeneration Paraquat 3.3416458197
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.5618045962
MESH:D012509 Sarcoma Doxorubicin 3.3916767912 18313854 15625365 15675481 17203757 17710206
MESH:D012512 Sarcoma, Ewing's Doxorubicin 8.4716326096 14601052
MESH:D012512 Sarcoma, Ewing's zoledronic acid 8.4716121404
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.1017846226
MESH:D012640 Seizures Cocaine 16.9410454489
MESH:D012640 Seizures Endosulfan 16.947539098 10698677
MESH:D012640 Seizures Ethanol 16.949754883
MESH:D012640 Seizures fipronil 16.9410698677
MESH:D012640 Seizures Lindane 16.947539098 12842176 15475178
MESH:D012640 Seizures Phenytoin 16.9415946322 3137016 3691417 19919933 16876388 11044598 9844417 10029267
MESH:D012878 Skin Neoplasms Doxorubicin 10.5115692506
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 10.518532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 10.5116192470
MESH:D012878 Skin Neoplasms Tobacco Smoke Pollution 10.5118590791
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 3.9015625365 17203757 16767912
MESH:D013088 Spermatocele Diethylstilbestrol 16.1016002989 16709447
MESH:D013088 Spermatocele Ethinyl Estradiol 16.1016709447
MESH:D013088 Spermatocele Tamoxifen 16.1016709447
MESH:D013119 Spinal Cord Injuries Progesterone 8.6016503802 15862959
MESH:D013119 Spinal Cord Injuries Tamoxifen 8.6019457130
MESH:D013262 Stevens-Johnson Syndrome Phenytoin 4.4920235791
MESH:D013272 Stomach Diseases beta Carotene 8.3917638125
MESH:D013272 Stomach Diseases Indomethacin 8.3917160473 16113693 15472012 16184426 17207306 18209964 10486359 16280098 10215738 15038085 10192188 17638125 18545984
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.9818456281
MESH:D013274 Stomach Neoplasms Ethanol 2.9818456281
MESH:D013274 Stomach Neoplasms Indomethacin 2.9815609394
MESH:D013276 Stomach Ulcer beta Carotene 8.7812500499
MESH:D013276 Stomach Ulcer Ethanol 8.7811906479 17189318 17918041 9562338 9211565 16755016
MESH:D013276 Stomach Ulcer Indomethacin 8.7815138204 17627676 15104355 11523592 16397915 15255614 10878458 12500499 16150113 16755016 10423059 18431645 17918041 11145282 17135157 10750652 12077510 16252198 1323529 18237397 18543354 11595415 11729361 12498302 12787963 18209962 12467913 11595431 14567935 17977527 11906479 18193104 18181030 16631530 18726076 16169175 17654042 16934674 17657623 18299717 17895592 18087811
MESH:D020521 Stroke Raloxifene 3.2716837676
MESH:D013375 Substance Withdrawal Syndrome Ethanol 3.659754883
MESH:D013436 Sulfhemoglobinemia Phenacetin 5.85978859
MESH:D024801 Tauopathies Camptothecin 4.9416930453
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.5615821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 2.9811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.5715669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.2012697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 8.987505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 8.9816010429 17909728
MESH:D013964 Thyroid Neoplasms Indomethacin 8.9811352223 18791128 14736730
MESH:D013978 Tibial Fractures Estradiol 11.3919048282
MESH:D013978 Tibial Fractures Raloxifene 11.3919048282
MESH:D014456 Ulcer Indomethacin 4.2110574470 17380554
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 19.1016712894 16452187 17306315
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 19.1017653716
MESH:D001749 Urinary Bladder Neoplasms Phenacetin 19.1011144890
MESH:D001749 Urinary Bladder Neoplasms Plant Preparations 19.1011251952
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 19.1017572228
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 19.1016712894 8653321 17572228
MESH:D001749 Urinary Bladder Neoplasms Tobacco Smoke Pollution 19.1012846360
MESH:D014581 Urticaria Acetaminophen 2.3510982225
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 3.4316175088
MESH:D014591 Uterine Diseases Diethylstilbestrol 4.4714652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 12.3815809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 12.3814692618
MESH:D014594 Uterine Neoplasms Sulindac 12.3818645019
MESH:D014605 Uveitis Cyclosporine 3.291336536
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 3.7716513791 16002989
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.8912125929
MESH:D054556 Venous Thromboembolism Raloxifene 4.5116837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.9214671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 3.5617678736 17638931 16364871 17334414
MESH:D014839 Vomiting Indomethacin 4.0511897121
MESH:D014846 Vulvar Neoplasms Raloxifene 4.8516343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.5515886252
MESH:D015430 Weight Gain Dietary Fats 3.1516723640
MESH:D014985 Xerophthalmia Cyclosporine 3.7417120751
Pathway ID Pathway Name
KEGG:04612 Antigen processing and presentation
KEGG:04142 Lysosome
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA27027
    • No data
    Releated disease ID Related disease Name
    PA447216Schizophrenia
    No data
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB02108 - 2-Aminoethanimidic Acid
    DB02148 - 3-Amino-4-Oxybenzyl-2-Butanone
    DB02685 - 3-Methylphenylalanine
    DB02855 - N-(3-Propylcarbamoyloxirane-2-Carbonyl)-Isoleucyl-Proline Neuroprotective Agents;Cysteine Proteinase Inhibitors
    DB03329 - 2-Pyridinethiol Molecule: Cathepsin B;Ec: 3.4.22.1
    DB03588 - Diphenylacetic Acid
    DB04126 - N-[1-Hydroxycarboxyethyl-Carbonyl]Leucylamino-2-Methyl-Butane
    DB04579 - N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-
    DB07160 - N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCINE
    DB07219 - BENZYL N-({(2S,3S)-3-[(PROPYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINATE
    DB07223 - METHYL N-({(2S,3S)-3-[(PROPYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINATE
    DB07224 - N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ALANINE
    DB07225 - N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ISOLEUCINE
    DB07231 - N-({(2S,3S)-3-[(BENZYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINE
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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