Annotation Detail for ALS2CR11
Basic Information
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| Gene Symbol: | ALS2CR11 ( DKFZp686H0636,FLJ25351,FLJ40332 ) |
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| Gene Full Name: | amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11 |
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| Band: | 2q33.1 |
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| Quick Links | Entrez ID:151254; OMIM: NA; Uniprot ID:AL2SA_HUMAN; ENSEMBL ID: ENSG00000155754; HGNC ID: |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C006780 |
bisphenol A |
bisphenol A results in increased expression of ALS2CR11 mRNA | increases expression | 20739668
|
| C006253 |
pirinixic acid |
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of ALS2CR11 mRNA | affects binding|decreases expression|increases activity | 19710929
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.72 | 18653653 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
4.37 | 16434500 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.70 | 19483382 |
| MESH:D001862 |
Bone Resorption |
|
bisphenol A |
4.41 | 11985600 |
| MESH:D001943 |
Breast Neoplasms |
|
bisphenol A |
2.42 | 17123778 |
| MESH:D002278 |
Carcinoma in Situ |
|
bisphenol A |
5.88 | 17123778 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
3.19 | 19176532 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.61 | 18249437 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
3.02 | 12083418 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
3.31 | 20131406 19236843 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.81 | 20558911 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.76 | 18467677 19772884 16221962 19176532 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.69 | 20558911 |
| MESH:D007333 |
Insulin Resistance |
|
bisphenol A |
8.31 | 16393666 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
8.31 | 16306350 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
1.95 | 15890375 16377806 20007298 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
4.27 | 16239165 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.30 | 19151258 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.33 | 16411023 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.14 | 17405874 |
| MESH:D009421 |
Nervous System Malformations |
|
bisphenol A |
4.65 | 16427766 11399458 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
1.90 | 20558911 |
| MESH:D010049 |
Ovarian Diseases |
|
bisphenol A |
5.88 | 11985600 |
| MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
bisphenol A |
4.84 | 10548101 |
| MESH:D019048 |
Prostatic Intraepithelial Neoplasia |
|
bisphenol A |
4.76 | 20887781 |
| MESH:D011471 |
Prostatic Neoplasms |
|
bisphenol A |
3.33 | 16740699 |
| MESH:D011629 |
Puberty, Precocious |
|
bisphenol A |
5.67 | 10548101 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.58 | 19058328 |
| MESH:D019966 |
Substance-Related Disorders |
|
bisphenol A |
4.87 | 16045194 16684133 |
| MESH:D014591 |
Uterine Diseases |
|
bisphenol A |
6.08 | 14652134 |
Related Pathway Information