AutismKB 2.0

Annotation Detail for GPR155


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Basic Information Top
Gene Symbol:GPR155 ( DEP.7,DEPDC3,FLJ31819,FLJ39346,PGR22 )
Gene Full Name: G protein-coupled receptor 155
Band: 2q31.1
Quick LinksEntrez ID:151556; OMIM: NA; Uniprot ID:GP155_HUMAN; ENSEMBL ID: ENSG00000163328; HGNC ID: 22951
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of GPR155 mRNAdecreases expression 19933214
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of GPR155 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of GPR155 mRNAaffects expression 17562736
D001104 Arbutin Arbutin results in decreased expression of GPR155 mRNAdecreases expression 17103032
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of GPR155 mRNAaffects expression 17484886
D004041 Dietary Fats Dietary Fats results in increased expression of GPR155 mRNAincreases expression 18042831
C041786 palm oil palm oil results in increased expression of GPR155 mRNAincreases expression 18042831
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of GPR155 mRNAdecreases expression 19933214
17337447
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.1814514962 15322242 11752688
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.7116835633
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.1711748828
MESH:D000799 Angioedema Acetaminophen 4.2210982225
MESH:D001161 Arteriosclerosis Dietary Fats 4.1915238619
MESH:D001321 Autistic Disorder marker/mechanism 17519220
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.2912125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.1715340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.9115746008
MESH:D001943 Breast Neoplasms Dietary Fats 1.9620435547
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9620435547
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 4.0816011737 16192424 16124888 16050911 16097048 15721981 10355542 15700767 3786805 16227642 18705752 15673190
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.9916835633
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 4.6916705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.693084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 4.6918788625
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.4918850075 18670907 16120746
MESH:D002386 Cataract Acetaminophen 2.7110977129
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.3816835633
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1916354765 8697196 15668235 15340226 12621046
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.2714669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2610048152 20055451 15322242
MESH:D003490 Cyanosis 2,4-dinitrotoluene 4.3218551238
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.7117107852
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 9.4621346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 9.4612392966 12705907 16393943 14725611 11739529 16177239 19370779 16081117 12594235 16781746 17562736 19739265 14550746 14986274 19164858 19923254 10663392 16227642 16485898 17522070 19420014 11421492 12540782 10915739 10774834 12958197 15619225 2444490 11743745 11834606 11529661 16109766 11461765 19085960 18713872 15968718 12153990 17906064 19416960 11287661 18071297
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 9.4610915739 15998439 16227642 11566570 9327722 6623471 16177239 7440962 19085960 3732212 6884620 15027814 2869522 19336974 15968718 7179309 17522070 3786805 21278145 7120509 4309450 10092053
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 9.4620420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.4719426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.9311462148
MESH:D050171 Dyslipidemias Dietary Fats 3.6218367378
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.6111000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.2818230668 15322242 16714409
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.2510568697 9294722
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.1911564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 8.6761145 16045604 12631006 16239168 12795759 17595544 15959796 19224547
MESH:D005234 Fatty Liver Dietary Fats 8.6718296743 17967931 19004024 19551842
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.7611858732
MESH:D005355 Fibrosis Carbon Tetrachloride 16.6318705752
MESH:D005355 Fibrosis Dietary Fats 16.6318296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 16.6320067830
MESH:D005756 Gastritis Acetaminophen 4.0516983495
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.9710696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.4410048152 11294989
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.5811000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.8819900420 19110552
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.2016120746 15340226 12621046
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.4215340226 18606429 8697196 16959395 16354765
MESH:D006930 Hyperalgesia Acetaminophen 2.8916870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.8716899240
MESH:D006937 Hypercholesterolemia Dietary Fats 3.8321332399
MESH:D006949 Hyperlipidemias Dietary Fats 3.8721332399
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9818850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.3915338365
MESH:D007249 Inflammation Dietary Fats 5.2920412841
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 5.2912200463 12878042
MESH:D007333 Insulin Resistance Dietary Fats 3.2511836018 18457598
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.5816580747
MESH:D007674 Kidney Diseases Acetaminophen 2.3212587719 15629191
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 3.1716705839
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 7.0317174718 16943688 17157831 11408273 11903743 21278145 16221502 17334410 16239168
MESH:D008103 Liver Cirrhosis Dietary Fats 7.0318296743
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 2.3418395914 15730626 14748882 15338365 12445418 15673190 12649538 17525996 12546737 17805973 17823541 18210741 12666154 12667390 15370692 12445421 14512876 12632514 16136751 18418968 14716496 16248980 16638106 17640975 15925388 17631135 18006644 15123356 17869086 17766677 12389079 13678700 18277467 17944888 17481882 18187930 17698563 12958196 17557913 18279442 12898905 12586293 15818738 14724832 17761835 15876570 17922224 16027843 18472332 17721639 17714472 18481824 18054572 10355542 18412020 18429990 18251166 18705752 14620537 16116963 18472094 15931870 18376398 16011737 16015684 18339082 17708605 15650968 15959796 15362042 18263696 17565644 15996030 12609069 18317297 18205269 12741479 12632512 17900296 15052691 20821823 16192424 18156304 15057751 16033810 14716833 18395095 15893842 11481614 16097048 18420326 17976157 18166357
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 2.3412878042
MESH:D008107 Liver Diseases Acetaminophen 4.0716611625 19784758 12587719 19014921 11587558 12969438 16610002 19460945
MESH:D008107 Liver Diseases Carbon Tetrachloride 4.0715830285 17285989 16964402 16246199 15720792
MESH:D017093 Liver Failure Carbon Tetrachloride 4.4715123358
MESH:D017114 Liver Failure, Acute Acetaminophen 10.1816871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 10.1814706259 16899240
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 4.6519294768
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 4.6516984957
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 6.2315583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 6.2312151625
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 1.2411884234 19555203
MESH:D008546 Melanoma, Experimental Acetaminophen 3.8719513568
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.2112213967
MESH:D009336 Necrosis 2,4-dinitrotoluene 4.2018551238
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.4914600291
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.0718514411
MESH:D009765 Obesity Dietary Fats 2.3319632207 21332399 20132043 17217161 18457598 11836018 20518802 18674790 16723640
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.6616049721 12819281
MESH:D010146 Pain Acetaminophen 2.5916870215
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.6212520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.8418163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.5311399792 11896295 11118676 11222880
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.1218990726
MESH:D012640 Seizures 2,4-dinitrotoluene 2.6818551238
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.1416192470
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.2812697716
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 2.3616049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.6510091137
MESH:D014581 Urticaria Acetaminophen 3.2410982225
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.9712125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.6215886252
MESH:D015430 Weight Gain Dietary Fats 3.9516723640
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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