AutismKB 2.0

Annotation Detail for TTC14


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Basic Information Top
Gene Symbol:TTC14 ( DKFZp313M1015,DRDL5813,FLJ00166,KIAA1980,PRO19630 )
Gene Full Name: tetratricopeptide repeat domain 14
Band: 3q26.33
Quick LinksEntrez ID:151613; OMIM: NA; Uniprot ID:TTC14_HUMAN; ENSEMBL ID: ENSG00000163728; HGNC ID: 24697
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of TTC14 mRNAaffects expression 21346803
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of TTC14 mRNAdecreases expression 20018196
C058305 phenethyl isothiocyanate phenethyl isothiocyanate results in decreased expression of TTC14 mRNAdecreases expression 17616710
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 1.7916705839
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 3.0120889678
MESH:D003093 Colitis, Ulcerative phenethyl isothiocyanate 3.7620423518
MESH:D003490 Cyanosis 2,4-dinitrotoluene 4.6718551238
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 2.0621346803 18551238
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1520426865
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 3.3616705839
MESH:D009336 Necrosis 2,4-dinitrotoluene 4.6018551238
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.8812819281 16049721
MESH:D012640 Seizures 2,4-dinitrotoluene 2.8118551238
MESH:D013733 Testicular Diseases phenethyl isothiocyanate 5.6815864552
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 2.4216049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 5.0610091137
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018