AutismKB 2.0

Annotation Detail for RNF38


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Basic Information Top
Gene Symbol:RNF38 ( FLJ21343 )
Gene Full Name: ring finger protein 38
Band: 9p13.2
Quick LinksEntrez ID:152006; OMIM: 612488; Uniprot ID:RNF38_HUMAN; ENSEMBL ID: ENSG00000137075; HGNC ID: 18052
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of RNF38 mRNAaffects expression 21346803
D000643 Ammonium Chloride Ammonium Chloride affects the expression of RNF38 mRNAaffects expression 16483693
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of RNF38 mRNAdecreases expression 19150397
C006780 bisphenol A bisphenol A results in increased expression of RNF38 mRNAincreases expression 18180321
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of RNF38 mRNAincreases expression 20360939
D005419 Flavonoids Flavonoids results in increased expression of RNF38 mRNAincreases expression 18035473
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.0218287403
MESH:D000236 Adenoma Diethylnitrosamine 3.0110737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 4.3618056438 17620307 17162532 19061943 19052882 16434500
MESH:D001862 Bone Resorption bisphenol A 4.1911985600
MESH:D001943 Breast Neoplasms bisphenol A 2.2217123778
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.2217474063
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 3.1116705839
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 3.1119822196 19052882 16681979 11831363 19107877 16328049 20512989 16935385 3581430 3084413 17055752 19539802 19394651 18506893 19335982 16288022 18494052 17138121 18788625 17173139 18978308 20935162 19519916 17428255 20514400 19171122 16878318 19701751 18691550 16502159 16779866 20524982 18665156 18210153 18971187 20214788 10737359 18393292 16807293 17978847 10672840 16569478 18785209 19208518 17162532 20727157 19383236 17761372 16830150 20432363 19919837 20007298 20101231 18056438 16540662 19418558 20084675 16698587 21159647
MESH:D002278 Carcinoma in Situ bisphenol A 5.4517123778
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.3820889678
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 7.382727394 7505956 17174075 21159647
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 3.9719052882
MESH:D003490 Cyanosis 2,4-dinitrotoluene 4.4318551238
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 2.2520387270
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 4.1421346803 18551238
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 4.1419107877
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.6416302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1320426865
MESH:D005234 Fatty Liver Diethylnitrosamine 3.5120387270 21071580
MESH:D007249 Inflammation Diethylnitrosamine 5.6718785209
MESH:D007249 Inflammation Flavonoids 5.6717296493
MESH:D007333 Insulin Resistance bisphenol A 3.4816393666
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 3.2416705839
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.9818407596 20032147 18665156 18522880 19638242
MESH:D008107 Liver Diseases Diethylnitrosamine 2.1617034775
MESH:D008113 Liver Neoplasms Diethylnitrosamine 2.3319850985 21278145 15885732 12112319 19090486 20137499 20405173 12771043 18978307 9163691 2862719 19254457 20118626 19812893 19427195 19256749 15175105 19499222 10737359 19638242 20492335 20101389 21167192 20452335 2422723 18644402 21071580 18648771 20434301 18977376 21047994 19294768 19073162 19690152 19833225 19426721 19996281 18754104 16942905 19255062 19642983 19551842 20501860 20583210
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 2.8118079962 17942915 18544905 18282651 18775883 2563599 18253720 16842330 18164116 19009564 9362446 17174075 21159647 19126423 16267830 3124819 18308698 18093689 17854601 19519916 19539802 19004024
MESH:D008175 Lung Neoplasms Diethylnitrosamine 1.7620970405 20512841 21163286 6695378
MESH:D009336 Necrosis 2,4-dinitrotoluene 4.3218551238
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.679029167 3581430
MESH:D009421 Nervous System Malformations bisphenol A 4.3511399458 16427766
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.6120387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.6420387270
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.7312819281 16049721
MESH:D010049 Ovarian Diseases bisphenol A 5.4511985600
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.5116540662
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.842563599
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 4.4110548101
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 4.5320887781
MESH:D011471 Prostatic Neoplasms bisphenol A 3.3616740699
MESH:D011629 Puberty, Precocious bisphenol A 5.2510548101
MESH:D012640 Seizures 2,4-dinitrotoluene 2.7318551238
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 1.7618456281
MESH:D019966 Substance-Related Disorders bisphenol A 4.4516045194 16684133
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 3.227505956
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 2.3816049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.7810091137
MESH:D014591 Uterine Diseases bisphenol A 5.5314652134
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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