AutismKB 2.0

Annotation Detail for DAB2IP


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Basic Information Top
Gene Symbol:DAB2IP ( AF9Q34,AIP1,DIP1/2,FLJ39072,KIAA1743 )
Gene Full Name: DAB2 interacting protein
Band: 9q33.2
Quick LinksEntrez ID:153090; OMIM: 609205; Uniprot ID:DAB2P_HUMAN; ENSEMBL ID: ENSG00000136848; HGNC ID: 17294
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of DAB2IP mRNAdecreases expression 19933214
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of DAB2IP mRNAaffects expression 21346803
D000643 Ammonium Chloride Ammonium Chloride affects the expression of DAB2IP mRNAaffects expression 16483693
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of DAB2IP mRNAincreases expression 17484886
D002117 Calcitriol Calcitriol results in decreased expression of DAB2IP mRNAdecreases expression 16002434
D007657 Ketone Bodies Ketone Bodies results in decreased expression of DAB2IP mRNAdecreases expression 16807920
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of DAB2IP mRNAdecreases expression 19933214
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.2415322242 14514962 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.9518287403
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.7716835633
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.2111748828
MESH:D017544 Aortic Aneurysm, Abdominal marker/mechanism 20622881
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.3312125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.2315340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.9315746008
MESH:D001943 Breast Neoplasms Calcitriol 2.0811237771
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.0820435547
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 4.143786805 16011737 16192424 15673190 16050911 16227642 16097048 10355542 18705752 15700767 16124888 15721981
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 3.0216835633
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 3.0916705839
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 3.0918788625
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 2.6811237771
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.5018850075 18670907 16120746
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.4116835633
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.2015668235 15340226 16354765 12621046 8697196
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.3117141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2610048152 15322242 20055451
MESH:D003490 Cyanosis 2,4-dinitrotoluene 4.3718551238
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.7217107852
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 6.5818551238 21346803
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 6.5810915739 16227642 4309450 3786805 15968718 9327722 16177239 7120509 21278145 3732212 2869522 17522070 7440962 6884620 19085960 15998439 7179309 15027814 19336974 11566570 6623471 10092053
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 6.5820420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.9611462148
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.6511000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.3516714409 18230668 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 4.2615138306
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.2910568697 9294722
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.2111564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 3.4515959796 16045604 12631006 19224547 12795759 61145 16239168 17595544
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.8111858732
MESH:D005355 Fibrosis Carbon Tetrachloride 9.8218705752
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 9.8220067830
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 5.0410696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.4611294989 10048152
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.6211000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.9219110552 19900420
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.2512621046 15340226 16120746
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.4916354765 18606429 8697196 15340226 16959395
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.9316899240
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9918850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.4515338365
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 1.9812878042 12200463
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.6216580747
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 3.2116705839
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 2.9411903743 16943688 21278145 17157831 16239168 11408273 17334410 16221502 17174718
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 2.3515673190 18251166 18006644 12958196 17823541 16192424 12546737 15996030 12649538 17714472 17761835 18395914 18472094 18412020 15730626 15123356 14620537 15818738 18277467 17631135 16136751 18187930 12632514 12632512 12898905 17766677 14748882 18339082 17481882 15362042 17869086 18376398 18472332 18705752 15370692 18263696 14512876 12445418 17708605 20821823 15338365 17565644 17557913 18420326 17805973 17976157 16638106 18429990 17922224 18481824 15925388 15052691 18210741 12609069 14716496 11481614 12666154 18156304 15931870 12667390 16248980 18418968 15893842 12741479 18317297 10355542 18205269 15876570 12445421 17525996 18395095 18054572 15650968 17944888 14716833 17698563 15959796 16033810 18166357 14724832 16116963 12586293 16027843 17640975 16097048 17900296 12389079 18279442 17721639 16011737 16015684 13678700 15057751
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 2.3512878042
MESH:D008107 Liver Diseases Carbon Tetrachloride 2.1315720792 15830285 16246199 17285989 16964402
MESH:D017093 Liver Failure Carbon Tetrachloride 4.5215123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.9514706259 16899240
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 4.6919294768
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 4.6916984957
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 6.3015583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 6.3012151625
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 1.2419555203 11884234
MESH:D009203 Myocardial Infarction marker/mechanism 20622881
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.2412213967
MESH:D009336 Necrosis 2,4-dinitrotoluene 4.2518551238
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.5414600291
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.6916049721 12819281
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.6912520081
MESH:D016491 Peripheral Vascular Diseases marker/mechanism 20622881
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.8918163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.5911399792 11222880 11896295 11118676
MESH:D011470 Prostatic Hyperplasia Calcitriol 5.1815572423
MESH:D011471 Prostatic Neoplasms marker/mechanism 18073375
MESH:D011471 Prostatic Neoplasms Calcitriol 3.5015754350 16289102 18247401 16644109 12479363
MESH:D011655 Pulmonary Embolism marker/mechanism 20622881
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.1718990726
MESH:D012640 Seizures 2,4-dinitrotoluene 2.7118551238
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.1516192470
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.3512697716
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 2.3716049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.7110091137
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 5.0412125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.6915886252
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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