AutismKB 2.0

Annotation Detail for CYBB


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CYBB ( CGD,GP91-1,GP91-PHOX,GP91PHOX,NOX2,p91-PHOX )
Gene Full Name: cytochrome b-245, beta polypeptide
Band: Xp21.1-p11.4
Quick LinksEntrez ID:1536; OMIM: 300481; Uniprot ID:CY24B_HUMAN; ENSEMBL ID: ENSG00000165168; HGNC ID: 2578
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04670Leukocyte transendothelial migration
hsa04145Phagosome
No data
Pathway IDPathway Name
200190RAC1 signaling pathway
No data
No data
Related Diseases/Disorders Top
Desease IDDesease Name
H00098Chronic granulomatous disease
Immune system diseases
Primary immunodeficiency
Desease IDDesease Name
1740Alzheimer's disease
1959Granulomatous disease
2051Leukemia
1882Malaria
No data
No data
Desease Name
Chronic granulomatous disease, X-linked
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000079 Acetaldehyde Acetaldehyde results in increased expression of CYBB mRNAincreases expression 18845238
D000082 Acetaminophen Acetaminophen results in increased expression of CYBB mRNAincreases expression 19739265
D000082 Acetaminophen manumycin inhibits the reaction [Acetaminophen results in increased expression of CYBB mRNA]decreases reaction|increases expression 19739265
D000082 Acetaminophen Methionine inhibits the reaction [Acetaminophen results in increased expression of CYBB mRNA]decreases reaction|increases expression 19739265
D000109 Acetylcholine CYBB gene mutant form inhibits the reaction [Nitroglycerin results in decreased susceptibility to Acetylcholine]decreases reaction|decreases response to substance 18522491
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CYBB mRNAaffects expression 16483693
D001151 Arsenic Arsenic results in decreased expression of CYBB mRNAdecreases expression 19654921
C006632 arsenic trioxide arsenic trioxide results in decreased expression of CYBB mRNAdecreases expression 20458559
D002211 Capsaicin CYBB protein affects the reaction [TRPV1 protein results in increased susceptibility to Capsaicin]affects reaction|increases response to substance 18203709
D002251 Carbon Tetrachloride CYBB gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 17105591
D002251 Carbon Tetrachloride CYBB gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA]decreases reaction|increases expression 17105591
D002251 Carbon Tetrachloride CYBB gene mutant form results in decreased susceptibility to Carbon Tetrachloridedecreases response to substance 17105591
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of CYBB proteindecreases expression 17854599
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of CYBB mRNAincreases expression 17854599
D009249 NADP CYBB protein promotes the reaction [[Doxorubicin co-treated with NADP] results in increased abundance of Superoxides]affects cotreatment|increases abundance|increases reaction 17275678
C057862 cyanoginosin LR cyanoginosin LR results in increased expression of CYBB mRNAincreases expression 17654400
D003907 Dexamethasone Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CYBB mRNA]decreases reaction|increases expression 9794432
D004041 Dietary Fats Dietary Fats results in decreased expression of CYBB mRNAdecreases expression 18042831
D004041 Dietary Fats [Dietary Fats co-treated with Fructose] results in increased expression of CYBB mRNAaffects cotreatment|increases expression 19632207
D004317 Doxorubicin CYBB protein promotes the reaction [[Doxorubicin co-treated with NADP] results in increased abundance of Superoxides]affects cotreatment|increases abundance|increases reaction 17275678
D004958 Estradiol Estradiol inhibits the reaction [AGT protein results in increased expression of CYBB mRNA]decreases reaction|increases expression 16097371
D004958 Estradiol Estradiol inhibits the reaction [AGT protein results in increased expression of CYBB protein]decreases reaction|increases expression 16097371
D000431 Ethanol Ethanol results in increased expression of CYBB mRNAincreases expression 18845238
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of CYBB mRNAincreases expression 17351261
D005419 Flavonoids Flavonoids results in decreased expression of CYBB mRNAdecreases expression 18035473
D005632 Fructose [Dietary Fats co-treated with Fructose] results in increased expression of CYBB mRNAaffects cotreatment|increases expression 19632207
D016627 Oxidopamine N-(4-O-glycerol-3-methoxybenzyl)nonivamide inhibits the reaction [Oxidopamine results in increased expression of CYBB protein]decreases reaction|increases expression 17855475
D016627 Oxidopamine Oxidopamine results in increased expression of CYBB proteinincreases expression 17855475
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of CYBB proteinincreases expression 17855475
D008070 Lipopolysaccharides N-(4-O-glycerol-3-methoxybenzyl)nonivamide inhibits the reaction [Lipopolysaccharides results in increased expression of CYBB protein]decreases reaction|increases expression 17855475
D008070 Lipopolysaccharides CYBB protein affects the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]affects reaction|increases expression 15795323
D008070 Lipopolysaccharides CYBB protein affects the reaction [Lipopolysaccharides results in increased expression of TNF protein]affects reaction|increases expression 15795323
D008070 Lipopolysaccharides Lipopolysaccharides results in increased activity of CYBB proteinincreases activity 19005069
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of CYBB mRNAincreases expression 15795323
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of CYBB proteinincreases expression 15795323
17855475
D008070 Lipopolysaccharides N-(4-O-glycerol-3-methoxybenzyl)nonivamide inhibits the reaction [Lipopolysaccharides results in increased expression of CYBB protein]decreases reaction|increases expression 17855475
C054474 manumycin manumycin inhibits the reaction [Acetaminophen results in increased expression of CYBB mRNA]decreases reaction|increases expression 19739265
D008715 Methionine Methionine inhibits the reaction [Acetaminophen results in increased expression of CYBB mRNA]decreases reaction|increases expression 19739265
D015655 1-Methyl-4-phenylpyridinium 1-Methyl-4-phenylpyridinium results in increased expression of CYBB mRNAincreases expression 18643790
D015655 1-Methyl-4-phenylpyridinium phenylmethylpyrazolone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CYBB mRNA]decreases reaction|increases expression 18643790
C080418 N-(4-O-glycerol-3-methoxybenzyl)nonivamide N-(4-O-glycerol-3-methoxybenzyl)nonivamide inhibits the reaction [Lipopolysaccharides results in increased expression of CYBB protein]decreases reaction|increases expression 17855475
C080418 N-(4-O-glycerol-3-methoxybenzyl)nonivamide N-(4-O-glycerol-3-methoxybenzyl)nonivamide inhibits the reaction [Oxidopamine results in increased expression of CYBB protein]decreases reaction|increases expression 17855475
C080418 N-(4-O-glycerol-3-methoxybenzyl)nonivamide N-(4-O-glycerol-3-methoxybenzyl)nonivamide inhibits the reaction [Lipopolysaccharides results in increased expression of CYBB protein]decreases reaction|increases expression 17855475
C052753 nebivolol nebivolol inhibits the reaction [AGT protein results in increased expression of CYBB mRNA]decreases reaction|increases expression 16940222
D005996 Nitroglycerin CYBB gene mutant form inhibits the reaction [Nitroglycerin results in decreased susceptibility to Acetylcholine]decreases reaction|decreases response to substance 18522491
D005996 Nitroglycerin CYBB gene mutant form results in decreased susceptibility to Nitroglycerindecreases response to substance 18522491
D005996 Nitroglycerin Nitroglycerin results in increased expression of CYBB mRNAincreases expression 16633368
D005996 Nitroglycerin rosuvastatin inhibits the reaction [Nitroglycerin results in increased expression of CYBB mRNA]decreases reaction|increases expression 16633368
D005996 Nitroglycerin Nitroglycerin results in decreased expression of CYBB mRNAdecreases expression 17493633
C041786 palm oil palm oil results in decreased expression of CYBB mRNAdecreases expression 18042831
D052638 Particulate Matter CYBB gene mutant form inhibits the reaction [Particulate Matter results in increased phosphorylation of MAPK1 protein]decreases reaction|increases phosphorylation 19371610
D052638 Particulate Matter CYBB gene mutant form inhibits the reaction [Particulate Matter results in increased phosphorylation of MAPK3 protein]decreases reaction|increases phosphorylation 19371610
D052638 Particulate Matter CYBB gene mutant form results in decreased susceptibility to Particulate Matterdecreases response to substance 19371610
D019800 Phenol Phenol results in increased expression of CYBB mRNAincreases expression 16785328
C005435 phenylmethylpyrazolone phenylmethylpyrazolone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CYBB mRNA]decreases reaction|increases expression 18643790
D028321 Plant Preparations Plant Preparations results in decreased expression of CYBB mRNAdecreases expression 19450372
D028321 Plant Preparations Plant Preparations results in decreased expression of CYBB proteindecreases expression 19450372
C025299 polyphenols polyphenols results in decreased expression of CYBB mRNAdecreases expression 19450372
C025299 polyphenols polyphenols results in decreased expression of CYBB proteindecreases expression 19450372
D011794 Quercetin Quercetin results in decreased expression of CYBB mRNAdecreases expression 19207477
D011794 Quercetin Quercetin results in decreased expression of CYBB proteindecreases expression 19207477
D011794 Quercetin Quercetin analog inhibits the reaction [AGT protein results in increased expression of CYBB mRNA]decreases reaction|increases expression 19794523
D017257 Ramipril Ramipril results in decreased expression of CYBB mRNAdecreases expression 16891913
C422923 rosuvastatin rosuvastatin inhibits the reaction [Nitroglycerin results in increased expression of CYBB mRNA]decreases reaction|increases expression 16633368
D013481 Superoxides IL1B protein promotes the reaction [CYBB protein results in increased chemical synthesis of Superoxides]increases chemical synthesis|increases reaction 16354686
D013481 Superoxides CYBB protein promotes the reaction [[Doxorubicin co-treated with NADP] results in increased abundance of Superoxides]affects cotreatment|increases abundance|increases reaction 17275678
D013755 Tetradecanoylphorbol Acetate Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CYBB mRNA]decreases reaction|increases expression 9794432
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in increased expression of CYBB mRNAincreases expression 9794432
C081489 valsartan valsartan inhibits the reaction [AGT protein results in increased expression of CYBB mRNA]decreases reaction|increases expression 15643130
C081489 valsartan valsartan inhibits the reaction [AGT protein results in increased expression of CYBB protein]decreases reaction|increases expression 15643130
C034028 vanadyl sulfate vanadyl sulfate results in decreased expression of CYBB mRNAdecreases expression 16330358
C025643 vinclozolin vinclozolin affects the expression of CYBB mRNAaffects expression 19015723
D015054 Zymosan CYBB protein affects the susceptibility to Zymosanaffects response to substance 14507659
D015054 Zymosan Zymosan results in increased activity of CYBB proteinincreases activity 19005069
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Capsaicin 7.6618926900
MESH:D000014 Abnormalities, Drug-Induced Ethanol 7.6618926900 17676605
MESH:D000138 Acidosis Ammonium Chloride 9.0418287403
MESH:D000138 Acidosis Ethanol 9.0411192467
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.5017505938
MESH:D058186 Acute Kidney Injury Capsaicin 8.2918460982
MESH:D058186 Acute Kidney Injury Superoxides 8.2918460982
MESH:D055371 Acute Lung Injury Lipopolysaccharides 8.4918653653 11850527
MESH:D055371 Acute Lung Injury Particulate Matter 8.4912396868
MESH:D000230 Adenocarcinoma arsenic trioxide 9.1219825857 11798837
MESH:D000230 Adenocarcinoma Doxorubicin 9.1217418594
MESH:D000230 Adenocarcinoma Estradiol 9.1211473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 9.1214692618
MESH:D018246 Adrenocortical Adenoma Arsenic 4.7717306315
MESH:D000419 Albuminuria Doxorubicin 4.1321441931
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.8815451040 15451039
MESH:D000505 Alopecia Capsaicin 4.3917569567
MESH:D000544 Alzheimer Disease Particulate Matter 3.6715513908
MESH:D000740 Anemia Zymosan 4.1818664788
MESH:D000743 Anemia, Hemolytic Quercetin 3.8517084956
MESH:D000756 Anemia, Sideroblastic Superoxides 5.2416910769
MESH:D000799 Angioedema Acetaminophen 3.4010982225
MESH:D000853 Anophthalmos Ethanol 4.4015513904
MESH:D001008 Anxiety Disorders Ethanol 7.8811141031
MESH:D001008 Anxiety Disorders vinclozolin 7.8819015723
MESH:D020261 Arsenic Poisoning Arsenic 2.7412569548 18414634 16835338 16251483
MESH:D001161 Arteriosclerosis Dietary Fats 8.5115238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 8.5111256880
MESH:D001169 Arthritis, Experimental Dexamethasone 10.8417659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 10.8415885639
MESH:D001169 Arthritis, Experimental Zymosan 10.8415142272 15188379 15944321 17659584 16872482
MESH:D001172 Arthritis, Rheumatoid phenylmethylpyrazolone 3.6816390820
MESH:D001249 Asthma Acetaldehyde 3.539600491
MESH:D001260 Ataxia Telangiectasia Quercetin 4.5515336622
MESH:D050197 Atherosclerosis Arsenic 6.6512928151 19371607
MESH:D050197 Atherosclerosis Ramipril 6.6511835907
MESH:D001289 Attention Deficit Disorder with Hyperactivity Oxidopamine 4.3614699433
MESH:D001321 Autistic Disorder Acetaminophen 2.4518445737
MESH:D001321 Autistic Disorder Methionine 2.4516917939 19056591 19267885
MESH:D001327 Autoimmune Diseases Quercetin 3.9919761891
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 3.2916206674
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.2614601052
MESH:D001859 Bone Neoplasms Phenol 4.8110556009
MESH:D001913 Bowen's Disease Phenol 5.3119293009
MESH:D001919 Bradycardia Capsaicin 4.6318207255
MESH:D002545 Brain Ischemia Capsaicin 4.5419211983
MESH:D001932 Brain Neoplasms Doxorubicin 3.4417150277
MESH:D001943 Breast Neoplasms Dietary Fats 2.2120435547
MESH:D001943 Breast Neoplasms Doxorubicin 2.2115567936 19526202 18234424 16264153 11325840 15136595 16595493 17369602 15939500 18628466 15993339 15668708 15634643 17983394 17426702 16115903 16322301 16096432 18382427 16826403 16935488 18695136 15692762 15994142
MESH:D001943 Breast Neoplasms Estradiol 2.2114630087 16675129 17018787 18497071 12948864 19861407 17289903 17261762
MESH:D001943 Breast Neoplasms Plant Preparations 2.2117398067
MESH:D001943 Breast Neoplasms Quercetin 2.2118628248
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.9311589617
MESH:D002056 Burns Ethanol 4.2316374292
MESH:D002105 Cadmium Poisoning Quercetin 5.1116962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.0316111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.3616097048 15673190 10355542 16011737 16124888 15700767 18705752 16050911 16227642 16192424 3786805 15721981
MESH:D002276 Carcinoid Tumor Doxorubicin 4.3716051944
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.3415504454 17687452
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 15.433084413
MESH:D006528 Carcinoma, Hepatocellular Arsenic 15.4317306315 16507464
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 15.4315073043 14691202 11135700 16217749 15553829
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 15.4318788625
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 15.4318059187 16023760 17876044 16234567
MESH:D006528 Carcinoma, Hepatocellular Estradiol 15.4316924424
MESH:D006528 Carcinoma, Hepatocellular Ethanol 15.4315763234 15289165 18788625
MESH:D006528 Carcinoma, Hepatocellular Quercetin 15.4319519916 12508355
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.5317234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.4319014326
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 2.9516201981 1485588
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.7412490120
MESH:D002294 Carcinoma, Squamous Cell Arsenic 9.7417687452 15504454 18922899
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 9.746189445
MESH:D002294 Carcinoma, Squamous Cell Plant Preparations 9.7417418620
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 9.7418922899
MESH:D002295 Carcinoma, Transitional Cell Arsenic 3.7018640142
MESH:D006332 Cardiomegaly Ethanol 10.2619332462
MESH:D006332 Cardiomegaly Quercetin 10.2619794523
MESH:D006332 Cardiomegaly valsartan 10.2619597038
MESH:D009202 Cardiomyopathies Doxorubicin 7.3516455267 18627295 15792986 17131338 17382496 15476868 16612575 17329180 15811867 16242529 17924179 16269455 17928571 15505089 17974986 16731534 16952015 17007740 16651473 16109756 16278810 17308081 16364871 17351982 17519947
MESH:D009202 Cardiomyopathies valsartan 7.3516247790
MESH:D002310 Cardiomyopathy, Alcoholic Acetaldehyde 6.0410525098
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.7917334414 16243910
MESH:D002318 Cardiovascular Diseases Arsenic 15.0417938729 19152805 15738583
MESH:D002318 Cardiovascular Diseases Particulate Matter 15.0412396868
MESH:D002318 Cardiovascular Diseases Plant Preparations 15.0416862667
MESH:D002318 Cardiovascular Diseases valsartan 15.0411230374
MESH:D002340 Carotid Artery Diseases Arsenic 3.9518022660 16973168
MESH:D016893 Carotid Stenosis Plant Preparations 5.7015158307
MESH:D002386 Cataract Acetaminophen 2.3210977129
MESH:D002471 Cell Transformation, Neoplastic Estradiol 2.4818566989
MESH:D002543 Cerebral Hemorrhage phenylmethylpyrazolone 5.4019095969
MESH:D002659 Child Development Disorders, Pervasive Methionine 4.1519267885
MESH:D002779 Cholestasis Ethinyl Estradiol 2.5616105132 11677210 17110522 17333356 17681005 15861022 16919318
MESH:D002971 Cleft Lip Ethanol 3.3515513904
MESH:D002972 Cleft Palate Ethanol 2.9915513904
MESH:D003110 Colonic Neoplasms Dexamethasone 5.4115824018
MESH:D003110 Colonic Neoplasms polyphenols 5.4116293270
MESH:D003110 Colonic Neoplasms Quercetin 5.4117191121 15741050 19440933 11134977 17148506 16640504 19056647
MESH:D015179 Colorectal Neoplasms arsenic trioxide 3.2420501625
MESH:D015179 Colorectal Neoplasms Doxorubicin 3.2418802399 18259882
MESH:D015179 Colorectal Neoplasms Quercetin 3.2418095365 18852136
MESH:D003324 Coronary Artery Disease Plant Preparations 6.2915158307
MESH:D003324 Coronary Artery Disease valsartan 6.2917719468
MESH:D003327 Coronary Disease Fructose 4.1918504504
MESH:D023903 Coronary Restenosis arsenic trioxide 3.7812609071
MESH:D003371 Cough Capsaicin 4.7410350223
MESH:D003384 Coxsackievirus Infections valsartan 5.4120392896
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.6510525206
MESH:D019465 Craniofacial Abnormalities Dexamethasone 3.6517728286
MESH:D019465 Craniofacial Abnormalities Ethanol 3.6510194807 19302082 11873399 15451039 11198716 15513904 15451040
MESH:D003456 Cryptorchidism vinclozolin 3.9314966744
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.7015213294
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 3.0112438553
MESH:D003921 Diabetes Mellitus, Experimental Fructose 22.3018603373
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 22.3019496084
MESH:D003921 Diabetes Mellitus, Experimental Ramipril 22.3011508273
MESH:D003921 Diabetes Mellitus, Experimental valsartan 22.3011508273
MESH:D003921 Diabetes Mellitus, Experimental vanadyl sulfate 22.3016684804
MESH:D003924 Diabetes Mellitus, Type 2 Fructose 3.2718603373
MESH:D003928 Diabetic Nephropathies Estradiol 8.1219279558
MESH:D003928 Diabetic Nephropathies valsartan 8.1211427623 18630688
MESH:D003967 Diarrhea Dexamethasone 3.307237001
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 16.4319416960 19923254 17522070 11743745 16485898 2444490 16781746 18713872 11834606 19420014 12958197 12540782 19370779 17562736 19085960 19164858 10774834 12594235 16109766 12392966 14986274 14550746 16081117 15619225 11421492 16393943 11461765 11739529 16227642 11529661 17906064 12153990 18071297 10663392 12705907 10915739 15968718 19739265 14725611 11287661 16177239
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 16.439327722 2869522 15998439 21278145 4309450 16177239 17522070 10915739 16227642 19085960 6623471 7440962 3786805 15968718 15027814 3732212 7179309 19336974 11566570 7120509 10092053 6884620
MESH:D056486 Drug-Induced Liver Injury cyanoginosin LR 16.4317654400
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 16.4317416283
MESH:D056486 Drug-Induced Liver Injury Ethanol 16.4311566570
MESH:D056486 Drug-Induced Liver Injury manumycin 16.4319739265
MESH:D056486 Drug-Induced Liver Injury polyphenols 16.4319370779
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.6619426721
MESH:D004362 Drug Toxicity Doxorubicin 12.3118602426
MESH:D004362 Drug Toxicity phenylmethylpyrazolone 12.3112231392 12649298
MESH:D004362 Drug Toxicity Plant Preparations 12.3111033412
MESH:D004381 Duodenal Ulcer Capsaicin 4.2911535926 10671773
MESH:D050171 Dyslipidemias Dietary Fats 3.1418367378
MESH:D004485 Eczema Dexamethasone 4.0512438553
MESH:D004487 Edema Dexamethasone 9.6119703484
MESH:D004487 Edema Tetradecanoylphorbol Acetate 9.6111698051 9599246 16716910 15177302 7812673 8113982 8273558
MESH:D004487 Edema Zymosan 9.617907874
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 2.7812538720
MESH:D016889 Endometrial Neoplasms Doxorubicin 6.5817359293
MESH:D016889 Endometrial Neoplasms Estradiol 6.5819148513 11473722 18566989
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.7218037988
MESH:D019446 Endotoxemia Lipopolysaccharides 9.5717637181 15328337 15821434
MESH:D019446 Endotoxemia phenylmethylpyrazolone 9.5712954792
MESH:D004935 Esophageal Diseases Capsaicin 5.2719566590
MESH:D004938 Esophageal Neoplasms arsenic trioxide 6.7612903497
MESH:D004938 Esophageal Neoplasms Ethanol 6.7616704527
MESH:D004938 Esophageal Neoplasms Plant Preparations 6.7616510608
MESH:D005234 Fatty Liver arsenic trioxide 31.0815073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 31.0812795759 61145 15959796 16045604 12631006 17595544 16239168 19224547
MESH:D005234 Fatty Liver Dietary Fats 31.0817967931 18296743 19004024 19551842
MESH:D005234 Fatty Liver Ethanol 31.0816409862 19236843 18620774
MESH:D005234 Fatty Liver Ethinyl Estradiol 31.0815345470
MESH:D005234 Fatty Liver Fructose 31.0819196556 18395287 18641190
MESH:D005234 Fatty Liver phenylmethylpyrazolone 31.0812795759
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.2217920746
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.8716946407 10194807 15451040 15513904
MESH:D005334 Fever Lipopolysaccharides 3.649205823 11852909
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 4.1619069698
MESH:D005355 Fibrosis Carbon Tetrachloride 23.3318705752
MESH:D005355 Fibrosis Dietary Fats 23.3318296743
MESH:D005355 Fibrosis Fructose 23.3318504504
MESH:D005355 Fibrosis Quercetin 23.3319474275
MESH:D005355 Fibrosis valsartan 23.3316893502
MESH:D005534 Foot Diseases Arsenic 5.126392382
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.8516904648
MESH:D005756 Gastritis Acetaminophen 9.6716983495
MESH:D005756 Gastritis Ethanol 9.6715046732
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.5016973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.8616417039
MESH:D005909 Glioblastoma Capsaicin 10.4418405923
MESH:D005909 Glioblastoma Doxorubicin 10.4417150277
MESH:D005909 Glioblastoma Quercetin 10.4419804834
MESH:D005910 Glioma Quercetin 2.8717643826
MESH:D015432 Glomerulonephritis, Membranoproliferative valsartan 5.1316928621
MESH:D018149 Glucose Intolerance Fructose 4.9319165636
MESH:D006105 Granulomatous Disease, Chronic marker/mechanism 11122248
OMIM:306400 GRANULOMATOUS DISEASE, CHRONIC, X-LINKED marker/mechanism|therapeutic 11045425
MESH:D006261 Headache Nitroglycerin 4.7511554966 11284996
MESH:D006258 Head and Neck Neoplasms Doxorubicin 3.2415692506
MESH:D006356 Heartburn Capsaicin 5.2719566590
MESH:D006331 Heart Diseases Doxorubicin 3.1818006777 16244372 16495754 17875725 12587719 18674790 17888722 16707910 14766674 16244371 16879835 16330681 16144979
MESH:D006333 Heart Failure Doxorubicin 6.7717481944
MESH:D006333 Heart Failure valsartan 6.7719027736
MESH:D006394 Hemangiosarcoma Doxorubicin 3.5215692506
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 4.0116366002
MESH:D006505 Hepatitis Carbon Tetrachloride 8.3019900420 19110552
MESH:D006505 Hepatitis Zymosan 8.3019110552
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 2.917520565
MESH:D006558 Herpes Genitalis Estradiol 4.5915709030
MESH:D006689 Hodgkin Disease Doxorubicin 3.0618501091 15147373 17606976
MESH:D019584 Hot Flashes Estradiol 3.3217088409
MESH:D006930 Hyperalgesia Acetaminophen 11.2616870215
MESH:D006930 Hyperalgesia Capsaicin 11.2617434803 17043245
MESH:D006930 Hyperalgesia Ethanol 11.2618783367
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.1016899240
MESH:D006937 Hypercholesterolemia Dietary Fats 3.2121332399
MESH:D006943 Hyperglycemia Quercetin 3.6611834736 18262572
MESH:D020138 Hyperhomocysteinemia Superoxides 4.9112615666
MESH:D006946 Hyperinsulinism Fructose 4.5418360027 14757778 15752949 19008412 18563319
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.0817050553
MESH:D006949 Hyperlipidemias Dietary Fats 8.2421332399
MESH:D006949 Hyperlipidemias Fructose 8.2415752949
MESH:D006973 Hypertension Arsenic 14.5416076760 11953799 9931084
MESH:D006973 Hypertension Dexamethasone 14.5417042910
MESH:D006973 Hypertension Fructose 14.5414573337 14568997 16843071 19008412 14633139
MESH:D006973 Hypertension Quercetin 14.5418356687
MESH:D006973 Hypertension valsartan 14.5418344623 16475468 20102058 12850387 10903974 11427623 12692753 18390891
MESH:D006974 Hypertension, Malignant valsartan 5.9711560862
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.6715338365
MESH:D015228 Hypertriglyceridemia Fructose 4.7019799862 19342510
MESH:D017379 Hypertrophy, Left Ventricular phenylmethylpyrazolone 5.0315824197
MESH:D006987 Hypesthesia Arsenic 5.1216093927
MESH:D007021 Hypospadias Ethinyl Estradiol 3.3916945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.0712013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 5.6917937319
MESH:D007248 Infertility, Male vinclozolin 5.6916467254
MESH:D007249 Inflammation Capsaicin 24.5116956363
MESH:D007249 Inflammation Dexamethasone 24.518960868 11099482
MESH:D007249 Inflammation Dietary Fats 24.5120412841
MESH:D007249 Inflammation Flavonoids 24.5117296493
MESH:D007249 Inflammation Lipopolysaccharides 24.5117237260 17255318 12878042 17963957 9205823
MESH:D007249 Inflammation polyphenols 24.5116366677
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 24.5111698051 7812673 7562506 8273558 15177302
MESH:D007249 Inflammation Zymosan 24.518014878 11289658
MESH:D007251 Influenza, Human Quercetin 4.0716624496
MESH:D007333 Insulin Resistance Dietary Fats 10.8418457598 11836018
MESH:D007333 Insulin Resistance Estradiol 10.8416393666 16627594
MESH:D007333 Insulin Resistance Fructose 10.8418981581 17133782 14633139 19008412 19586609 19342510 18057795 14757778 18563319 19799862 14573337
MESH:D007410 Intestinal Diseases Superoxides 5.0210210152
MESH:D002532 Intracranial Aneurysm phenylmethylpyrazolone 4.9019381132
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.2317255318
MESH:D043183 Irritable Bowel Syndrome Zymosan 5.4117553498
MESH:D007511 Ischemia phenylmethylpyrazolone 5.1216301206
MESH:D007569 Jaw Abnormalities Ethanol 4.0215513904
MESH:D007627 Keloid Quercetin 4.5317086741
MESH:D007642 Keratosis Arsenic 4.5616930632 12749816
MESH:D055623 Keratosis, Actinic Phenol 6.0019293009
MESH:D007674 Kidney Diseases Acetaminophen 20.5415629191 12587719
MESH:D007674 Kidney Diseases Doxorubicin 20.5415369732 15699352 16775033
MESH:D007674 Kidney Diseases Estradiol 20.5415618244
MESH:D007674 Kidney Diseases phenylmethylpyrazolone 20.5418085390
MESH:D007674 Kidney Diseases Quercetin 20.5416962696
MESH:D007674 Kidney Diseases valsartan 20.5410903974 12164870 16893502
MESH:D007676 Kidney Failure, Chronic Doxorubicin 3.7716707910
MESH:D007680 Kidney Neoplasms Estradiol 2.6415610895
MESH:D007859 Learning Disorders Ethanol 3.7915451040
MESH:D007938 Leukemia arsenic trioxide 5.7315070760
MESH:D007938 Leukemia Quercetin 5.7317468513
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.7216085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.4117077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.8816972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.1114633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.3819077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.0616467208 16968895 17050201 20471514 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 6.8217339181
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 6.8219642359 12018890 15336539 16966277 16112521 17217047 17712046 12679006 16331271 17869043 17107899 16330433 15748426 19225113 12712474 11161223 9834237 15213294 19075265 17649720 11468182 16891316 19035177 15622746 16823087
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.9416882451
MESH:D007970 Leukopenia Lipopolysaccharides 4.2715821434
MESH:D007984 Leydig Cell Tumor vinclozolin 4.3016417039
MESH:D017880 Limb Deformities, Congenital Ethanol 3.5017676605
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 9.6516239168 16221502 17334410 11903743 11408273 21278145 16943688 17174718 17157831
MESH:D008103 Liver Cirrhosis Dietary Fats 9.6518296743
MESH:D008103 Liver Cirrhosis Ethanol 9.6515289165
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.6618295389
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 16.8118339082 15057751 18210741 18429990 17761835 18205269 16248980 11481614 17631135 17900296 17766677 16033810 15123356 20821823 17805973 18279442 15673190 18166357 15338365 12445418 15362042 17698563 12632512 17565644 15996030 15959796 18187930 15650968 12586293 12445421 17708605 15876570 12958196 18418968 16192424 17976157 17714472 18420326 15818738 13678700 12649538 18054572 15730626 16027843 14620537 16015684 18251166 15893842 18376398 12389079 14716496 12667390 18277467 12609069 18472094 18705752 12546737 18263696 14748882 18317297 18006644 10355542 16136751 18156304 17869086 16011737 18472332 17525996 12632514 14724832 12898905 17640975 12666154 17721639 17823541 16116963 14512876 15052691 17557913 12741479 17922224 17944888 18412020 18395095 16638106 18481824 18395914 15925388 17481882 14716833 15370692 16097048 15931870
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 16.8116718785
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 16.8116439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 16.8114716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 16.8118166357
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 16.8112878042
MESH:D008106 Liver Cirrhosis, Experimental Methionine 16.8115158331
MESH:D008106 Liver Cirrhosis, Experimental Plant Preparations 16.8117724770
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 16.8112741479
MESH:D008106 Liver Cirrhosis, Experimental valsartan 16.8115619341 15504291 16872305
MESH:D008107 Liver Diseases Acetaminophen 11.1612969438 16610002 19014921 16611625 19784758 11587558 19460945 12587719
MESH:D008107 Liver Diseases Arsenic 11.1611134558
MESH:D008107 Liver Diseases Capsaicin 11.1616956363
MESH:D008107 Liver Diseases Carbon Tetrachloride 11.1616246199 15720792 15830285 17285989 16964402
MESH:D008107 Liver Diseases polyphenols 11.1616698588
MESH:D008108 Liver Diseases, Alcoholic Ethanol 4.2317207112 17347304
MESH:D017093 Liver Failure Carbon Tetrachloride 3.7415123358
MESH:D017114 Liver Failure, Acute Acetaminophen 8.1716871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 8.1714706259 16899240
MESH:D008113 Liver Neoplasms Arsenic 9.2816368122
MESH:D008113 Liver Neoplasms arsenic trioxide 9.2814682389
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 9.2819294768
MESH:D008113 Liver Neoplasms Quercetin 9.2818980244
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 11.9120377131
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 11.9115583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 11.9117085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Quercetin 11.9119519916
MESH:D008133 Long QT Syndrome arsenic trioxide 3.0215213294
MESH:D055370 Lung Injury Lipopolysaccharides 3.5921114838
MESH:D008175 Lung Neoplasms Acetaldehyde 9.7017372256
MESH:D008175 Lung Neoplasms Arsenic 9.7017976673 17306315 19168569
MESH:D008175 Lung Neoplasms arsenic trioxide 9.7019825857 11798837
MESH:D008175 Lung Neoplasms Dexamethasone 9.7015824018 11195469
MESH:D008175 Lung Neoplasms Doxorubicin 9.706189445 17418594
MESH:D008175 Lung Neoplasms Quercetin 9.7016280456
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 9.7011807781
MESH:D008223 Lymphoma Doxorubicin 3.1516098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.4417654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.1515621674
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 8.4615458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 8.4611807958 17203775 11408345 16891317
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 8.468985016
MESH:D020149 Manganese Poisoning Estradiol 4.0419453300
MESH:D008545 Melanoma Doxorubicin 2.2316827129
MESH:D008546 Melanoma, Experimental Acetaminophen 3.1519513568
MESH:D008569 Memory Disorders Ethanol 3.7818411066 15451040
MESH:D008654 Mesothelioma Doxorubicin 2.8817638057
MESH:D008659 Metabolic Diseases phenylmethylpyrazolone 5.0916301206
MESH:D024821 Metabolic Syndrome X Fructose 4.4619165636 17098227 18497449 17261469 16815490
MESH:D008708 Methemoglobinemia Nitroglycerin 4.343537620
MESH:D020326 Migraine without Aura Nitroglycerin 4.7214659530
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.1115792986
MESH:D009062 Mouth Neoplasms Plant Preparations 4.4417418620
MESH:D052016 Mucositis Doxorubicin 4.3617415656
MESH:D009101 Multiple Myeloma arsenic trioxide 10.5011468182 14977855 15949261 19417148 19549372
MESH:D009101 Multiple Myeloma Capsaicin 10.5017505005
MESH:D009101 Multiple Myeloma Dexamethasone 10.5016118317 15744524 15867202
MESH:D009102 Multiple Organ Failure Zymosan 4.8115259001 12879239 15213630 12130978 17724436 10479408 15834315 18160304 10890648 15241586
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.2318349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 6.7116882451 16105982
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 6.719809623
MESH:D009203 Myocardial Infarction Doxorubicin 12.1415857846 19429709
MESH:D009203 Myocardial Infarction Nitroglycerin 12.1414729435
MESH:D009203 Myocardial Infarction Quercetin 12.1419595682
MESH:D009203 Myocardial Infarction Ramipril 12.1411835907
MESH:D017202 Myocardial Ischemia Arsenic 3.6415371236
MESH:D015428 Myocardial Reperfusion Injury marker/mechanism 19207477
MESH:D015428 Myocardial Reperfusion Injury Estradiol 7.4616810080
MESH:D015428 Myocardial Reperfusion Injury Quercetin 7.4619207477
MESH:D009205 Myocarditis Particulate Matter 5.5312563109
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.5516624393
MESH:D009362 Neoplasm Metastasis Doxorubicin 2.7718259882
MESH:D009369 Neoplasms Quercetin 2.5915185748
MESH:D009389 Neovascularization, Pathologic Estradiol 3.3017289903
MESH:D009401 Nephrosis Doxorubicin 4.3516899518 16636307
MESH:D009404 Nephrotic Syndrome Doxorubicin 3.6415640375 16889571
MESH:D009410 Nerve Degeneration 1-Methyl-4-phenylpyridinium 4.7117433543
MESH:D009421 Nervous System Malformations Estradiol 3.2411399458 16427766
MESH:D009436 Neural Tube Defects Arsenic 6.5016620997
MESH:D009436 Neural Tube Defects arsenic trioxide 6.5010525206
MESH:D009447 Neuroblastoma Doxorubicin 3.0315555623
MESH:D019636 Neurodegenerative Diseases 1-Methyl-4-phenylpyridinium 12.3916353238
MESH:D019636 Neurodegenerative Diseases Acetaminophen 12.3918514411
MESH:D019636 Neurodegenerative Diseases Oxidopamine 12.3918514411
MESH:D020078 Neurogenic Inflammation Arsenic 15.6117056641
MESH:D020078 Neurogenic Inflammation Capsaicin 15.6117961222
MESH:D020078 Neurogenic Inflammation Quercetin 15.6117929310
MESH:D009765 Obesity Capsaicin 7.0119056576
MESH:D009765 Obesity Dietary Fats 7.0111836018 21332399 19632207 17217161 18674790 20518802 16723640 18457598 20132043
MESH:D009765 Obesity Fructose 7.0118585860 17707055
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 3.8219495926
MESH:D012516 Osteosarcoma Doxorubicin 3.7715930896
MESH:D010051 Ovarian Neoplasms Arsenic 10.0617306315
MESH:D010051 Ovarian Neoplasms arsenic trioxide 10.0612452020 16624393 19769630
MESH:D010051 Ovarian Neoplasms Estradiol 10.0619401270
MESH:D010051 Ovarian Neoplasms Quercetin 10.0619005980
MESH:D010146 Pain Acetaminophen 9.5216870215
MESH:D010146 Pain Capsaicin 9.5216996476 17084039 17434803 18987195 19081190 17043245
MESH:D010146 Pain Phenol 9.5217610455
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 10.9915580305
MESH:D010190 Pancreatic Neoplasms Ethanol 10.9912384795
MESH:D010190 Pancreatic Neoplasms Quercetin 10.9916965848
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 10.9915976015
MESH:D010195 Pancreatitis phenylmethylpyrazolone 4.5020035747
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.2911578682
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 3.8812065085 8330346 18922899 18404319
MESH:D010235 Paraganglioma arsenic trioxide 3.7619927285
MESH:D010300 Parkinson Disease 1-Methyl-4-phenylpyridinium 3.9717433543
MESH:D010302 Parkinson Disease, Secondary Oxidopamine 5.0415893579 11771942
MESH:D010392 Pemphigus Phenol 6.0016522979 17163923
MESH:D010523 Peripheral Nervous System Diseases Arsenic 3.7716093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 4.5616905509 6392382 15371236
MESH:D010538 Peritonitis Zymosan 4.4617826846 11985352 18557954 15979727 19641140 17371808 19088179 18977430 15259001 18760300 14761945
MESH:D003557 Phyllodes Tumor Doxorubicin 4.7217983394
MESH:D010864 Pilonidal Sinus Phenol 6.0019655223 15622588
MESH:D010997 Pleural Neoplasms Doxorubicin 4.7217638057
MESH:D011014 Pneumonia Lipopolysaccharides 4.1211605937 12224865
MESH:D011041 Poisoning Phenol 4.328825745
MESH:D011230 Precancerous Conditions Quercetin 3.6219056647
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.3021297632
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 3.4718042343 18220299 19015723
MESH:D011469 Prostatic Diseases vinclozolin 4.5018220299
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.5020887781
MESH:D011471 Prostatic Neoplasms Arsenic 1.9216140617
MESH:D011471 Prostatic Neoplasms arsenic trioxide 1.9219131511
MESH:D011471 Prostatic Neoplasms Doxorubicin 1.9216729912 15749863 18437689 16868541 15897917 16888761
MESH:D011471 Prostatic Neoplasms Estradiol 1.9216740699
MESH:D011471 Prostatic Neoplasms Quercetin 1.9214715546 17292933
MESH:D011472 Prostatitis vinclozolin 4.5018629315
MESH:D011507 Proteinuria Arsenic 8.4221343184
MESH:D011507 Proteinuria valsartan 8.4218344623 12164870 17664856
MESH:D011537 Pruritus Ethinyl Estradiol 2.8915861022 16919318
MESH:D011658 Pulmonary Fibrosis Particulate Matter 6.0612475806
MESH:D011658 Pulmonary Fibrosis valsartan 6.0617241526
MESH:D051437 Renal Insufficiency Doxorubicin 3.8017922066
MESH:D015427 Reperfusion Injury Capsaicin 10.2119211983 18460982
MESH:D015427 Reperfusion Injury phenylmethylpyrazolone 10.2115948865 15629865 16753835 14654979 15086910 16041266
MESH:D015427 Reperfusion Injury Superoxides 10.2118460982
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 3.6218379247 11700416
MESH:D012130 Respiratory Hypersensitivity Acetylcholine 7.599413022
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 7.5910835634
MESH:D012220 Rhinitis Acetaldehyde 4.3817050345
MESH:D012509 Sarcoma Doxorubicin 3.6217710206 15625365 15675481 18313854 17203757 16767912
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 8.9216646077
MESH:D012512 Sarcoma, Ewing's Doxorubicin 8.9214601052 16326096
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.3617846226
MESH:D012554 Schistosomiasis japonica Quercetin 5.1116862918
MESH:D012559 Schizophrenia Methionine 3.6215737665
MESH:D012640 Seizures Ethanol 2.899754883
MESH:D018805 Sepsis Zymosan 4.3011441115
MESH:D012871 Skin Diseases Arsenic 2.6319834688 18709164 16702368 17938729 16353154 6392382 16759981 17548696 15952646 17453740 17050553
MESH:D012878 Skin Neoplasms Arsenic 8.4317029826 17050553 15504454 19538983 17976673 16251483
MESH:D012878 Skin Neoplasms Doxorubicin 8.4315692506
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 8.438985016 12065085 11807781 8330346 18404319
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.1517203757 16767912 15625365
MESH:D013088 Spermatocele Ethinyl Estradiol 10.5916709447
MESH:D013088 Spermatocele Phenol 10.5918646496
MESH:D013272 Stomach Diseases Dexamethasone 3.8915472012
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.5217007042
MESH:D013274 Stomach Neoplasms Ethanol 2.5218456281
MESH:D013276 Stomach Ulcer Dexamethasone 6.2915138204
MESH:D013276 Stomach Ulcer Ethanol 6.299211565 9562338 17918041 17189318 11906479 16755016
MESH:D013375 Substance Withdrawal Syndrome Ethanol 3.889754883
MESH:D013705 Temporomandibular Joint Disorders Capsaicin 11.9017997062
MESH:D013705 Temporomandibular Joint Disorders polyphenols 11.9017997062
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.7915821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.2211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.7915669648
MESH:D013964 Thyroid Neoplasms arsenic trioxide 6.2519014326
MESH:D013964 Thyroid Neoplasms Doxorubicin 6.2517909728 16010429
MESH:D013978 Tibial Fractures Estradiol 4.2519048282
MESH:D016171 Torsades de Pointes arsenic trioxide 3.5315213294
MESH:D014277 Trigeminal Neuralgia Phenol 6.0016527771 10223447
MESH:D001749 Urinary Bladder Neoplasms Arsenic 13.8819322015 15987713 17976673 18640142 17306315 19429237 11144890
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 13.8811780464 12845720 12973940 20435036
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 13.8817653716
MESH:D001749 Urinary Bladder Neoplasms Plant Preparations 13.8811251952
MESH:D001749 Urinary Bladder Neoplasms Quercetin 13.8816720314
MESH:D014581 Urticaria Acetaminophen 2.5810982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 2.8914692618
MESH:D014605 Uveitis Dexamethasone 10.831336536
MESH:D014605 Uveitis Zymosan 10.8311006244
MESH:D014652 Vascular Diseases Arsenic 4.3017056641
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.1515869587 14671159
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 3.8017638931 17678736 16364871 17334414
MESH:D020257 Ventricular Remodeling valsartan 5.2719027736
MESH:D014860 Warts Phenol 5.6619122958
MESH:D015430 Weight Gain Dietary Fats 3.3816723640
Pathway ID Pathway Name
KEGG:04670 Leukocyte transendothelial migration
KEGG:04380 Osteoclast differentiation
KEGG:04145 Phagosome
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA27076
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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