Annotation Detail for ADRB2
Basic Information Top
| Gene Symbol: | ADRB2 ( ADRB2R,ADRBR,B2AR,BAR,BETA2AR ) |
|---|---|
| Gene Full Name: | adrenergic, beta-2-, receptor, surface |
| Band: | 5q32 |
| Quick Links | Entrez ID:154; OMIM: 109690; Uniprot ID:ADRB2_HUMAN; ENSEMBL ID: ENSG00000169252; HGNC ID: 286 |
| Relate to Another Database: | SFARIGene; denovo-db |
| No data |
| Pathway ID | Pathway Name |
|---|---|
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04020 | Calcium signaling pathway |
| hsa04144 | Endocytosis |
| hsa04970 | Salivary secretion |
| Pathway ID | Pathway Name |
|---|---|
| Signaling by GPCR |
| Pathway ID | Pathway Name |
|---|---|
| 200060 | Arf6 signaling events |
| 200046 | Arf6 trafficking events |
| Pathway ID | Pathway Name |
|---|---|
| P04378 | Beta2 adrenergic receptor signaling pathway |
| P00026 | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway |
| No data |
| Desease ID | Desease Name |
|---|---|
| H00079 | Asthma |
| Immune system diseases | |
| Allergies and autoimmune diseases |
| Desease ID | Desease Name |
|---|---|
| 1781 | Rheumatoid arthritis |
| 1804 | Chronic obstructive airway disease |
| 1826 | Cystic fibrosis |
| 1831 | Prostate cancer |
| 1842 | Sickle cell disease |
| 1856 | Obesity |
| 1870 | Drug abuse |
| 1904 | Diabetes mellitus |
| 1918 | Atherosclerosis |
| 1930 | Graves' disease |
| 1982 | Myopathy |
| 2005 | Bronchial disease |
| 2091 | Hypertension |
| 2057 | Premature birth |
| 2060 | Glaucoma |
| 2066 | Lung cancer |
| 2075 | Heart failure |
| 2102 | Polycystic ovary syndrome |
| 2124 | Autistic disorder |
| 2145 | Subarachnoid hemorrhage |
| 2197 | Metabolism disease |
| 2220 | Dermatitis |
| 2231 | Arthritis |
| 1882 | Malaria |
| Desease Name |
|---|
| AGING |
| blood pressure, arterial |
| colorectal cancer |
| CARDIOVASCULAR |
| cholesterol, LDL |
| cardiomyopathy |
| increased body weight and dyslipoproteinaemia involving triglyceride-rich lipoproteins |
| flow-mediated dilatation of the brachial artery |
| CANCER |
| PSYCH |
| Weight Gain |
| Bronchial asthma |
| PEF |
| Asthma |
| Obesity and Type 2 Diabetes |
| Nocturnal asthma |
| hypertriglyceridemia and the development of fatty liver |
| Asthma smokers |
| breast cancer |
| hypertension |
| multiple sclerosis |
| Asthma severity |
| epinephrine lung function norepinephrine |
| subcutaneous fat accumulation |
| IMMUNE |
| metabolic syndrome |
| attention deficit hyperactivity disorder |
| METABOLIC |
| Body Weight |
| pulmonary function |
| persistent bronchial hyperresponsiveness |
| preterm delivery |
| heart rate |
| Decreased airway responsiveness |
| human intelligence |
| obesity |
| FEV1 |
| High total IgE |
| BHR |
| DEVELOPMENTAL |
| interstitial cystitis |
| Steroid-requiring asthma in sedentary women |
| REPRODUCTION |
| diabetes, type 2 |
| Parasitic infection |
| limb deficiency anomalies |
| respiratory airway resistance |
| INFECTION |
| Heart Failure |
| No data |
| Desease Name |
|---|
| Asthma, nocturnal, susceptibility to |
| Obesity, susceptibility to |
| Beta-2-adrenoreceptor agonist, reduced response to |
| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| C548651 | 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester | 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of ADRB2 mRNA | increases expression | 19933214 |
| C472791 | 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid | 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in increased expression of ADRB2 mRNA | increases expression | 16788091 |
| C085755 | 4-(1H-imidazol-4-ylmethyl)piperidine | 4-(1H-imidazol-4-ylmethyl)piperidine promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein] | increases activity|increases reaction | 17196553 |
| D000242 | Cyclic AMP | [ADRB1 protein binds to ADRB2 protein] which results in increased abundance of Cyclic AMP | affects binding|increases abundance | 19419905 |
| D000242 | Cyclic AMP | [Albuterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP | affects binding|increases abundance|increases activity | 12920204 10516654 10952688 16980553 |
| D000242 | Cyclic AMP | Atenolol inhibits the reaction [[Albuterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| D000242 | Cyclic AMP | Atenolol inhibits the reaction [[Epinephrine binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| D000242 | Cyclic AMP | Atenolol inhibits the reaction [[Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| D000242 | Cyclic AMP | Atenolol inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| D000242 | Cyclic AMP | [Epinephrine binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP | affects binding|increases abundance|increases activity | 12920204 |
| D000242 | Cyclic AMP | [Fenoterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP | affects binding|increases abundance|increases activity | 16980553 |
| D000242 | Cyclic AMP | [formoterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP | affects binding|increases abundance|increases activity | 16980553 |
| D000242 | Cyclic AMP | [Forskolin co-treated with 1-Methyl-3-isobutylxanthine] promotes the reaction [[ADRB1 protein binds to ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|affects cotreatment|increases abundance|increases reaction | 19419905 |
| D000242 | Cyclic AMP | ICI 118551 inhibits the reaction [[Albuterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| D000242 | Cyclic AMP | ICI 118551 inhibits the reaction [[Epinephrine binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| D000242 | Cyclic AMP | ICI 118551 inhibits the reaction [[Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| D000242 | Cyclic AMP | ICI 118551 inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| D000242 | Cyclic AMP | [Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP | affects binding|increases abundance|increases activity | 12920204 16036225 16980553 10516654 |
| D000242 | Cyclic AMP | [Metaproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP | affects binding|increases abundance|increases activity | 16980553 |
| D000242 | Cyclic AMP | Propranolol inhibits the reaction [[Albuterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 10952688 |
| D000242 | Cyclic AMP | Propranolol inhibits the reaction [[Epinephrine binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| D000242 | Cyclic AMP | Propranolol inhibits the reaction [[Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| D000242 | Cyclic AMP | Propranolol inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| D000242 | Cyclic AMP | [salmeterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP | affects binding|increases abundance|increases activity | 10516654 |
| D000242 | Cyclic AMP | [Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP | affects binding|increases abundance|increases activity | 10516654 12920204 |
| D000242 | Cyclic AMP | ADRB2 protein promotes the reaction [Isoproterenol results in increased abundance of Cyclic AMP] | increases abundance|increases reaction | 18378355 |
| D000242 | Cyclic AMP | [Terbutaline results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP | increases abundance|increases activity | 10857765 |
| D000242 | Cyclic AMP | Alprenolol inhibits the reaction [[Alprenolol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 17718540 |
| D000242 | Cyclic AMP | ICI 118551 inhibits the reaction [[ICI 118551 binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 17718540 |
| D000242 | Cyclic AMP | [Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP | affects binding|increases abundance|increases activity | 17718540 |
| D000242 | Cyclic AMP | Propranolol inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 17718540 |
| D000242 | Cyclic AMP | [Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP | affects binding|increases abundance|increases activity | 17718540 17480040 |
| D016604 | Aflatoxin B1 | Aflatoxin B1 affects the expression of ADRB2 protein | affects expression | 20106945 |
| D000420 | Albuterol | ADRB2 gene polymorphism results in decreased susceptibility to Albuterol | decreases response to substance | 15687340 |
| D000420 | Albuterol | Albuterol binds to and results in increased activity of ADRB2 protein | affects binding|increases activity | 10952688 10516654 12920204 16980553 |
| D000420 | Albuterol | [Albuterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP | affects binding|increases abundance|increases activity | 10516654 12920204 10952688 16980553 |
| D000420 | Albuterol | [Albuterol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein | affects binding|increases activity|increases phosphorylation | 16980553 |
| D000420 | Albuterol | [Albuterol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein | affects binding|increases activity|increases phosphorylation | 16980553 |
| D000420 | Albuterol | Albuterol results in decreased expression of ADRB2 protein | decreases expression | 16980553 |
| D000420 | Albuterol | Albuterol results in increased phosphorylation of ADRB2 protein | increases phosphorylation | 14722251 16980553 |
| D000420 | Albuterol | Atenolol inhibits the reaction [Albuterol binds to and results in increased activity of ADRB2 protein] | affects binding|decreases reaction|increases activity | 12920204 |
| D000420 | Albuterol | Atenolol inhibits the reaction [[Albuterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| D000420 | Albuterol | ICI 118551 inhibits the reaction [Albuterol binds to and results in increased activity of ADRB2 protein] | affects binding|decreases reaction|increases activity | 12920204 |
| D000420 | Albuterol | ICI 118551 inhibits the reaction [[Albuterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| D000420 | Albuterol | Propranolol inhibits the reaction [Albuterol binds to and results in increased activity of ADRB2 protein] | affects binding|decreases reaction|increases activity | 12920204 |
| D000420 | Albuterol | Propranolol inhibits the reaction [[Albuterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 10952688 |
| D000420 | Albuterol | Albuterol binds to and results in increased activity of ADRB2 protein | affects binding|increases activity | 19120125 |
| D000420 | Albuterol | Albuterol binds to and results in increased activity of ADRB2 protein | affects binding|increases activity | 15467267 |
| D000526 | Alprenolol | Alprenolol binds to and results in increased activity of ADRB2 protein | affects binding|increases activity | 17718540 |
| D000526 | Alprenolol | Alprenolol inhibits the reaction [[Alprenolol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 17718540 |
| D000638 | Amiodarone | Amiodarone results in decreased expression of ADRB2 protein | decreases expression | 1653643 |
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of ADRB2 mRNA | affects expression | 16483693 |
| D017638 | Asbestos, Crocidolite | Asbestos, Crocidolite results in increased expression of ADRB2 mRNA | increases expression | 18687144 |
| D001262 | Atenolol | Atenolol inhibits the reaction [Albuterol binds to and results in increased activity of ADRB2 protein] | affects binding|decreases reaction|increases activity | 12920204 |
| D001262 | Atenolol | Atenolol inhibits the reaction [[Albuterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| D001262 | Atenolol | Atenolol inhibits the reaction [Epinephrine binds to and results in increased activity of ADRB2 protein] | affects binding|decreases reaction|increases activity | 12920204 |
| D001262 | Atenolol | Atenolol inhibits the reaction [[Epinephrine binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| D001262 | Atenolol | Atenolol inhibits the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein] | affects binding|decreases reaction|increases activity | 12920204 |
| D001262 | Atenolol | Atenolol inhibits the reaction [[Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| D001262 | Atenolol | Atenolol inhibits the reaction [Terbutaline binds to and results in increased activity of ADRB2 protein] | affects binding|decreases reaction|increases activity | 12920204 |
| D001262 | Atenolol | Atenolol inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| D001374 | Azacitidine | Azacitidine affects the expression of ADRB2 mRNA | affects expression | 19002953 |
| D001507 | Beclomethasone | Beclomethasone results in increased expression of ADRB2 mRNA | increases expression | 15679717 |
| D015123 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of ADRB2 mRNA | increases expression | 20382639 |
| C095105 | bexarotene | bexarotene results in decreased expression of ADRB2 mRNA | decreases expression | 17178900 |
| C053541 | bicalutamide | bicalutamide inhibits the reaction [Triiodothyronine results in increased expression of ADRB2 protein] | decreases reaction|increases expression | 18454446 |
| C053541 | bicalutamide | bicalutamide results in decreased expression of ADRB2 mRNA | decreases expression | 18454446 |
| C053541 | bicalutamide | bicalutamide results in decreased expression of ADRB2 protein | decreases expression | 18454446 |
| C057368 | BRL 37344 | [BRL 37344 binds to and results in increased activity of ADRB2 protein] which results in increased uptake of Glucose | affects binding|increases activity|increases uptake | 18552870 |
| C057368 | BRL 37344 | ICI 118551 inhibits the reaction [[BRL 37344 binds to and results in increased activity of ADRB2 protein] which results in increased uptake of Glucose] | affects binding|decreases reaction|increases activity|increases uptake | 18552870 |
| C045916 | broxaterol | broxaterol binds to and results in increased activity of ADRB2 protein | affects binding|increases activity | 16648137 |
| D019819 | Budesonide | Budesonide results in increased expression of ADRB2 protein | increases expression | 20061444 |
| D002078 | Butoxamine | Butoxamine binds to and results in decreased activity of ADRB2 protein | affects binding|decreases activity | 15908513 11821714 |
| D002087 | Butyrates | Butyrates results in increased expression of ADRB2 mRNA | increases expression | 8120022 |
| D002087 | Butyrates | Butyrates results in increased expression of ADRB2 protein | increases expression | 8120022 |
| D002118 | Calcium | [Terbutaline binds to and results in increased activity of ADRB2 protein] which affects the abundance of Calcium | affects abundance|affects binding|increases activity | 10372813 |
| C033394 | CGP 12177 | CGP 12177 binds to ADRB2 protein | affects binding | 17628611 |
| C033394 | CGP 12177 | CGP 12177 binds to and results in decreased activity of ADRB2 protein | affects binding|decreases activity | 12732361 |
| C049763 | CGP 20712A | CGP 20712A inhibits the reaction [[Fenoterol binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine] | affects binding|decreases reaction|decreases response to substance|increases activity | 16474418 |
| C049763 | CGP 20712A | CGP 20712A inhibits the reaction [[salmeterol binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine] | affects binding|decreases reaction|decreases response to substance|increases activity | 16474418 |
| C049763 | CGP 20712A | CGP 20712A inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine] | affects binding|decreases reaction|decreases response to substance|increases activity | 16474418 |
| C049763 | CGP 20712A | CGP 20712A binds to and results in decreased activity of ADRB2 protein | affects binding|decreases activity | 12877941 17196553 |
| D002712 | Chlorides | [Terbutaline results in increased activity of ADRB2 protein] which results in increased transport of Chlorides | increases activity|increases transport | 20054151 |
| D002713 | Chlorine | [Ozone co-treated with Chlorine] affects the expression of ADRB2 mRNA | affects cotreatment|affects expression | 18636392 |
| D004390 | Chlorpyrifos | Chlorpyrifos affects the expression of ADRB2 mRNA | affects expression | 18812211 |
| D004390 | Chlorpyrifos | Chlorpyrifos results in increased expression of ADRB2 mRNA | increases expression | 17452286 |
| D002976 | Clenbuterol | [Clenbuterol binds to and results in increased activity of ADRB2 protein] which results in decreased uptake of Glucose | affects binding|decreases uptake|increases activity | 18552870 |
| D002976 | Clenbuterol | ICI 118551 inhibits the reaction [[Clenbuterol binds to and results in increased activity of ADRB2 protein] which results in decreased uptake of Glucose] | affects binding|decreases reaction|decreases uptake|increases activity | 18552870 |
| D002976 | Clenbuterol | Clenbuterol binds to and results in increased activity of ADRB2 protein | affects binding|increases activity | 15710352 15178407 10898105 |
| C086108 | clobenpropit | clobenpropit promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein] | increases activity|increases reaction | 17196553 |
| D003010 | Clorgyline | Clorgyline results in increased expression of ADRB2 mRNA | increases expression | 19691856 |
| D003035 | Cobalt | Cobalt promotes the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein] | affects binding|increases activity|increases reaction | 11752207 |
| D003300 | Copper | Copper binds to and results in increased activity of ADRB2 protein | affects binding|increases activity | 16567806 |
| D003345 | Corticosterone | Corticosterone results in increased expression of ADRB2 mRNA | increases expression | 15755911 |
| D016572 | Cyclosporine | Cyclosporine results in decreased expression of ADRB2 mRNA | decreases expression | 20106945 |
| D003634 | DDT | DDT affects the activity of ADRB2 protein | affects activity | 17157474 |
| C014347 | decitabine | decitabine affects the expression of ADRB2 mRNA | affects expression | 17194187 |
| D003907 | Dexamethasone | Dexamethasone results in decreased expression of ADRB2 mRNA | decreases expression | 15760667 |
| D003907 | Dexamethasone | [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADRB2 mRNA | affects cotreatment|increases expression | 16054899 |
| D003907 | Dexamethasone | Dexamethasone results in increased expression of ADRB2 mRNA | increases expression | 9074950 |
| D003907 | Dexamethasone | Mifepristone inhibits the reaction [Dexamethasone results in increased expression of ADRB2 mRNA] | decreases reaction|increases expression | 9074950 |
| D003976 | Diazinon | Diazinon results in increased expression of ADRB2 mRNA | increases expression | 17452286 |
| D004026 | Dieldrin | Dieldrin affects the expression of ADRB2 mRNA | affects expression | 18812211 |
| D004082 | Dihydroalprenolol | Dihydroalprenolol binds to ADRB2 protein | affects binding | 15477226 17196553 |
| D002117 | Calcitriol | Calcitriol results in decreased expression of ADRB2 mRNA | decreases expression | 16002434 |
| D004280 | Dobutamine | ADRB2 gene polymorphism affects the susceptibility to Dobutamine | affects response to substance | 17094270 |
| D007980 | Levodopa | [ICI 118551 binds to and results in decreased activity of ADRB2 protein] which affects the uptake of Levodopa | affects binding|affects uptake|decreases activity | 10894789 |
| D007980 | Levodopa | ICI 118551 inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in decreased uptake of Levodopa] | affects binding|decreases reaction|decreases uptake|increases activity | 10894789 |
| D007980 | Levodopa | [Terbutaline binds to and results in increased activity of ADRB2 protein] which results in decreased uptake of Levodopa | affects binding|decreases uptake|increases activity | 10894789 |
| D004298 | Dopamine | ICI 118551 inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Dopamine] | affects binding|decreases reaction|increases abundance|increases activity | 10894789 |
| D004298 | Dopamine | [Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Dopamine | affects binding|increases abundance|increases activity | 10894789 |
| D017292 | Doxazosin | Doxazosin results in increased expression of ADRB2 protein | increases expression | 18084315 |
| D004317 | Doxorubicin | ADRB2 affects the susceptibility to Doxorubicin | affects response to substance | 16458323 |
| D004837 | Epinephrine | Atenolol inhibits the reaction [Epinephrine binds to and results in increased activity of ADRB2 protein] | affects binding|decreases reaction|increases activity | 12920204 |
| D004837 | Epinephrine | Atenolol inhibits the reaction [[Epinephrine binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| D004837 | Epinephrine | Epinephrine binds to and results in increased activity of ADRB2 protein | affects binding|increases activity | 12920204 |
| D004837 | Epinephrine | [Epinephrine binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP | affects binding|increases abundance|increases activity | 12920204 |
| D004837 | Epinephrine | Epinephrine promotes the reaction [ADRBK1 protein results in increased phosphorylation of ADRB2 protein] | increases phosphorylation|increases reaction | 14722251 |
| D004837 | Epinephrine | Epinephrine promotes the reaction [GRK5 protein results in increased phosphorylation of ADRB2 protein] | increases phosphorylation|increases reaction | 14722251 |
| D004837 | Epinephrine | Epinephrine results in increased phosphorylation of and results in increased localization of ADRB2 protein | increases localization|increases phosphorylation | 14722251 |
| D004837 | Epinephrine | ICI 118551 inhibits the reaction [Epinephrine binds to and results in increased activity of ADRB2 protein] | affects binding|decreases reaction|increases activity | 12920204 |
| D004837 | Epinephrine | ICI 118551 inhibits the reaction [[Epinephrine binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| D004837 | Epinephrine | Propranolol inhibits the reaction [Epinephrine binds to and results in increased activity of ADRB2 protein] | affects binding|decreases reaction|increases activity | 12920204 |
| D004837 | Epinephrine | Propranolol inhibits the reaction [[Epinephrine binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| D004837 | Epinephrine | Epinephrine results in increased activity of ADRB2 protein | increases activity | 11164953 |
| D004837 | Epinephrine | [Epinephrine results in increased activity of ADRB2 protein] which results in increased secretion of Histamine | increases activity|increases secretion | 11164953 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in increased expression of ADRB2 mRNA | increases expression | 12655037 15834898 |
| D005280 | Fenoterol | Fenoterol binds to and results in increased activity of ADRB2 protein | affects binding|increases activity | 16980553 |
| D005280 | Fenoterol | [Fenoterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP | affects binding|increases abundance|increases activity | 16980553 |
| D005280 | Fenoterol | [Fenoterol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein | affects binding|increases activity|increases phosphorylation | 16980553 |
| D005280 | Fenoterol | [Fenoterol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein | affects binding|increases activity|increases phosphorylation | 16980553 |
| D005280 | Fenoterol | Fenoterol results in increased phosphorylation of ADRB2 protein | increases phosphorylation | 14722251 |
| D005280 | Fenoterol | CGP 20712A inhibits the reaction [[Fenoterol binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine] | affects binding|decreases reaction|decreases response to substance|increases activity | 16474418 |
| D005280 | Fenoterol | Fenoterol binds to and results in increased activity of ADRB2 protein | affects binding|increases activity | 16474418 |
| D005280 | Fenoterol | [Fenoterol binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine | affects binding|decreases response to substance|increases activity | 16474418 |
| C012629 | formoterol | formoterol binds to and results in increased activity of ADRB2 protein | affects binding|increases activity | 16980553 |
| C012629 | formoterol | [formoterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP | affects binding|increases abundance|increases activity | 16980553 |
| C012629 | formoterol | [formoterol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein | affects binding|increases activity|increases phosphorylation | 16980553 |
| C012629 | formoterol | [formoterol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein | affects binding|increases activity|increases phosphorylation | 16980553 |
| C012629 | formoterol | formoterol results in increased phosphorylation of ADRB2 protein | increases phosphorylation | 16980553 14722251 |
| C012629 | formoterol | formoterol binds to and results in increased activity of ADRB2 protein | affects binding|increases activity | 20061444 |
| D005576 | Forskolin | [Forskolin co-treated with 1-Methyl-3-isobutylxanthine] promotes the reaction [[ADRB1 protein binds to ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|affects cotreatment|increases abundance|increases reaction | 19419905 |
| D005576 | Forskolin | [Forskolin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of [ADRB1 protein binds to ADRB2 protein] | affects binding|affects cotreatment|increases activity | 19419905 |
| D005576 | Forskolin | [[Forskolin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of [ADRB1 protein binds to ADRB2 protein]] affects the reaction [KCNH2 protein results in increased transport of Potassium] | affects binding|affects cotreatment|affects reaction|increases activity|increases transport | 19419905 |
| D005576 | Forskolin | Forskolin results in increased phosphorylation of ADRB2 protein | increases phosphorylation | 14722251 |
| D005947 | Glucose | [BRL 37344 binds to and results in increased activity of ADRB2 protein] which results in increased uptake of Glucose | affects binding|increases activity|increases uptake | 18552870 |
| D005947 | Glucose | [Clenbuterol binds to and results in increased activity of ADRB2 protein] which results in decreased uptake of Glucose | affects binding|decreases uptake|increases activity | 18552870 |
| D005947 | Glucose | ICI 118551 inhibits the reaction [[BRL 37344 binds to and results in increased activity of ADRB2 protein] which results in increased uptake of Glucose] | affects binding|decreases reaction|increases activity|increases uptake | 18552870 |
| D005947 | Glucose | ICI 118551 inhibits the reaction [[Clenbuterol binds to and results in increased activity of ADRB2 protein] which results in decreased uptake of Glucose] | affects binding|decreases reaction|decreases uptake|increases activity | 18552870 |
| D006632 | Histamine | Histamine promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein] | increases activity|increases reaction | 17196553 |
| D006632 | Histamine | Histamine results in increased activity of ADRB2 protein | increases activity | 17196553 |
| D006632 | Histamine | [Epinephrine results in increased activity of ADRB2 protein] which results in increased secretion of Histamine | increases activity|increases secretion | 11164953 |
| D006632 | Histamine | [Isoproterenol results in increased activity of ADRB2 protein] which results in increased secretion of Histamine | increases activity|increases secretion | 11164953 |
| D006632 | Histamine | [Terbutaline results in increased activity of ADRB2 protein] which results in increased secretion of Histamine | increases activity|increases secretion | 11164953 |
| C026777 | ICI 118551 | ICI 118551 binds to and results in decreased activity of ADRB2 protein | affects binding|decreases activity | 12606629 |
| C026777 | ICI 118551 | ICI 118551 binds to and results in decreased activity of ADRB2 protein | affects binding|decreases activity | 10952688 16036225 |
| C026777 | ICI 118551 | ICI 118551 inhibits the reaction [Albuterol binds to and results in increased activity of ADRB2 protein] | affects binding|decreases reaction|increases activity | 12920204 |
| C026777 | ICI 118551 | ICI 118551 inhibits the reaction [[Albuterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| C026777 | ICI 118551 | ICI 118551 inhibits the reaction [Epinephrine binds to and results in increased activity of ADRB2 protein] | affects binding|decreases reaction|increases activity | 12920204 |
| C026777 | ICI 118551 | ICI 118551 inhibits the reaction [[Epinephrine binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| C026777 | ICI 118551 | ICI 118551 inhibits the reaction [Iodocyanopindolol binds to ADRB2 protein] | affects binding|decreases reaction | 10344530 |
| C026777 | ICI 118551 | ICI 118551 inhibits the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein] | affects binding|decreases reaction|increases activity | 16036225 12920204 |
| C026777 | ICI 118551 | ICI 118551 inhibits the reaction [[Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| C026777 | ICI 118551 | ICI 118551 inhibits the reaction [Terbutaline binds to and results in increased activity of ADRB2 protein] | affects binding|decreases reaction|increases activity | 12920204 |
| C026777 | ICI 118551 | ICI 118551 inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| C026777 | ICI 118551 | ICI 118551 inhibits the reaction [[BRL 37344 binds to and results in increased activity of ADRB2 protein] which results in increased uptake of Glucose] | affects binding|decreases reaction|increases activity|increases uptake | 18552870 |
| C026777 | ICI 118551 | ICI 118551 inhibits the reaction [[Clenbuterol binds to and results in increased activity of ADRB2 protein] which results in decreased uptake of Glucose] | affects binding|decreases reaction|decreases uptake|increases activity | 18552870 |
| C026777 | ICI 118551 | ICI 118551 inhibits the reaction [Isoproterenol results in increased activity of ADRB2 protein] | decreases reaction|increases activity | 18820136 |
| C026777 | ICI 118551 | ICI 118551 binds to and results in decreased activity of ADRB2 protein | affects binding|decreases activity | 12608646 10344530 10894789 20054151 11096136 |
| C026777 | ICI 118551 | [ICI 118551 binds to and results in decreased activity of ADRB2 protein] which affects the uptake of Levodopa | affects binding|affects uptake|decreases activity | 10894789 |
| C026777 | ICI 118551 | ICI 118551 inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in decreased uptake of Levodopa] | affects binding|decreases reaction|decreases uptake|increases activity | 10894789 |
| C026777 | ICI 118551 | ICI 118551 inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Dopamine] | affects binding|decreases reaction|increases abundance|increases activity | 10894789 |
| C026777 | ICI 118551 | ICI 118551 inhibits the reaction [Terbutaline results in increased activity of ADRB2 protein] | decreases reaction|increases activity | 20054151 |
| C026777 | ICI 118551 | ICI 118551 binds to and results in decreased activity of ADRB2 protein | affects binding|decreases activity | 11804996 17622774 17718540 18820136 12732361 14764656 15908513 17196553 15178407 |
| C026777 | ICI 118551 | ICI 118551 inhibits the reaction [[ICI 118551 binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 17718540 |
| C029899 | imidazole | imidazole promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein] | increases activity|increases reaction | 17196553 |
| D020120 | Iodocyanopindolol | ICI 118551 inhibits the reaction [Iodocyanopindolol binds to ADRB2 protein] | affects binding|decreases reaction | 10344530 |
| D020120 | Iodocyanopindolol | Iodocyanopindolol binds to ADRB2 protein | affects binding | 10344530 |
| D015056 | 1-Methyl-3-isobutylxanthine | [Forskolin co-treated with 1-Methyl-3-isobutylxanthine] promotes the reaction [[ADRB1 protein binds to ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|affects cotreatment|increases abundance|increases reaction | 19419905 |
| D015056 | 1-Methyl-3-isobutylxanthine | [Forskolin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of [ADRB1 protein binds to ADRB2 protein] | affects binding|affects cotreatment|increases activity | 19419905 |
| D015056 | 1-Methyl-3-isobutylxanthine | [[Forskolin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of [ADRB1 protein binds to ADRB2 protein]] affects the reaction [KCNH2 protein results in increased transport of Potassium] | affects binding|affects cotreatment|affects reaction|increases activity|increases transport | 19419905 |
| D015056 | 1-Methyl-3-isobutylxanthine | [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADRB2 mRNA | affects cotreatment|increases expression | 16054899 |
| D007545 | Isoproterenol | 4-(1H-imidazol-4-ylmethyl)piperidine promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein] | increases activity|increases reaction | 17196553 |
| D007545 | Isoproterenol | Atenolol inhibits the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein] | affects binding|decreases reaction|increases activity | 12920204 |
| D007545 | Isoproterenol | Atenolol inhibits the reaction [[Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| D007545 | Isoproterenol | clobenpropit promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein] | increases activity|increases reaction | 17196553 |
| D007545 | Isoproterenol | Cobalt promotes the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein] | affects binding|increases activity|increases reaction | 11752207 |
| D007545 | Isoproterenol | Histamine promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein] | increases activity|increases reaction | 17196553 |
| D007545 | Isoproterenol | ICI 118551 inhibits the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein] | affects binding|decreases reaction|increases activity | 16036225 12920204 |
| D007545 | Isoproterenol | ICI 118551 inhibits the reaction [[Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| D007545 | Isoproterenol | imidazole promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein] | increases activity|increases reaction | 17196553 |
| D007545 | Isoproterenol | Isoproterenol binds to and results in increased activity of ADRB2 protein | affects binding|increases activity | 16980553 12920204 10516654 16036225 |
| D007545 | Isoproterenol | [Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP | affects binding|increases abundance|increases activity | 16036225 10516654 12920204 16980553 |
| D007545 | Isoproterenol | [Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein | affects binding|increases activity|increases phosphorylation | 16980553 |
| D007545 | Isoproterenol | [Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein | affects binding|increases activity|increases phosphorylation | 16980553 |
| D007545 | Isoproterenol | Isoproterenol results in increased phosphorylation of ADRB2 protein | increases phosphorylation | 16980553 |
| D007545 | Isoproterenol | Propranolol inhibits the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein] | affects binding|decreases reaction|increases activity | 12920204 |
| D007545 | Isoproterenol | Propranolol inhibits the reaction [[Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| D007545 | Isoproterenol | Zinc promotes the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein] | affects binding|increases activity|increases reaction | 11752207 |
| D007545 | Isoproterenol | ADRB2 protein affects the reaction [Isoproterenol results in increased expression of IL18 mRNA] | affects reaction|increases expression | 15178407 |
| D007545 | Isoproterenol | CAV1 protein promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein] | increases activity|increases reaction | 18820136 |
| D007545 | Isoproterenol | ICI 118551 inhibits the reaction [Isoproterenol results in increased activity of ADRB2 protein] | decreases reaction|increases activity | 18820136 |
| D007545 | Isoproterenol | Isoproterenol results in increased activity of ADRB2 protein | increases activity | 18820136 |
| D007545 | Isoproterenol | ADRB2 protein promotes the reaction [Isoproterenol results in increased abundance of Cyclic AMP] | increases abundance|increases reaction | 18378355 |
| D007545 | Isoproterenol | Isoproterenol results in increased activity of ADRB2 protein | increases activity | 11164953 |
| D007545 | Isoproterenol | [Isoproterenol results in increased activity of ADRB2 protein] which results in increased secretion of Histamine | increases activity|increases secretion | 11164953 |
| D007545 | Isoproterenol | Isoproterenol binds to and results in increased activity of ADRB2 protein | affects binding|increases activity | 17718540 15710352 |
| D007545 | Isoproterenol | [Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP | affects binding|increases abundance|increases activity | 17718540 |
| D008055 | Lipids | ADRB2 gene polymorphism affects the reaction [Terbutaline results in increased metabolism of Lipids] | affects reaction|increases metabolic processing | 11429395 |
| D008055 | Lipids | ADRB2 protein affects the metabolism of Lipids | affects metabolic processing | 15798957 |
| D008055 | Lipids | ADRB2 protein promotes the reaction [Terbutaline results in increased metabolism of Lipids] | increases metabolic processing|increases reaction | 11429395 |
| D008070 | Lipopolysaccharides | ADRB2 protein promotes the reaction [Terbutaline promotes the reaction [Lipopolysaccharides results in increased expression of IL8 protein]] | increases expression|increases reaction | 9258252 |
| D008070 | Lipopolysaccharides | Lipopolysaccharides results in increased expression of ADRB2 mRNA | increases expression | 12057914 |
| D008070 | Lipopolysaccharides | ADRB2 protein affects the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] | affects reaction|increases expression | 10469353 |
| D008070 | Lipopolysaccharides | ADRB2 protein promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] | increases expression|increases reaction | 10525314 |
| D008070 | Lipopolysaccharides | ADRB2 protein promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] | increases expression|increases reaction | 10525314 |
| D008070 | Lipopolysaccharides | ADRB2 protein promotes the reaction [Terbutaline inhibits the reaction [Lipopolysaccharides results in increased activity of MAPK1 protein]] | decreases reaction|increases activity|increases reaction | 10469353 |
| D008070 | Lipopolysaccharides | ADRB2 protein promotes the reaction [Terbutaline inhibits the reaction [Lipopolysaccharides results in increased activity of MAPK3 protein]] | decreases reaction|increases activity|increases reaction | 10469353 |
| D008070 | Lipopolysaccharides | ADRB2 protein promotes the reaction [Terbutaline inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]] | decreases reaction|increases expression|increases reaction | 11096136 |
| D008070 | Lipopolysaccharides | ADRB2 protein promotes the reaction [Terbutaline inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]] | decreases reaction|increases expression|increases reaction | 11096136 |
| D008070 | Lipopolysaccharides | ADRB2 protein promotes the reaction [Terbutaline inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]] | decreases reaction|increases expression|increases reaction | 11096136 10857765 |
| D008070 | Lipopolysaccharides | ADRB2 protein promotes the reaction [Terbutaline promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]] | increases expression|increases reaction | 11096136 |
| D009921 | Metaproterenol | Metaproterenol binds to and results in increased activity of ADRB2 protein | affects binding|increases activity | 16980553 |
| D009921 | Metaproterenol | [Metaproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP | affects binding|increases abundance|increases activity | 16980553 |
| D009921 | Metaproterenol | Metaproterenol results in decreased expression of ADRB2 protein | decreases expression | 16980553 |
| D009921 | Metaproterenol | Metaproterenol results in increased phosphorylation of ADRB2 protein | increases phosphorylation | 16980553 |
| D009921 | Metaproterenol | Metaproterenol binds to and results in increased activity of ADRB2 protein | affects binding|increases activity | 15052282 |
| D008688 | Methacholine Compounds | ADRB2 protein affects the susceptibility to Methacholine Compounds | affects response to substance | 10926562 |
| D015735 | Mifepristone | Mifepristone inhibits the reaction [Dexamethasone results in increased expression of ADRB2 mRNA] | decreases reaction|increases expression | 9074950 |
| D009248 | Nadolol | Nadolol binds to and results in decreased activity of ADRB2 protein | affects binding|decreases activity | 17622774 |
| D009532 | Nickel | Nickel affects the expression of ADRB2 mRNA | affects expression | 18812211 |
| D009569 | Nitric Oxide | ADRB2 protein results in decreased abundance of Nitric Oxide | decreases abundance | 10580815 |
| D009638 | Norepinephrine | Norepinephrine binds to and results in increased activity of ADRB2 protein | affects binding|increases activity | 10344530 |
| D009638 | Norepinephrine | Octopamine inhibits the reaction [Norepinephrine binds to ADRB2 protein] | affects binding|decreases reaction | 10344530 |
| D009655 | Octopamine | Octopamine inhibits the reaction [Norepinephrine binds to ADRB2 protein] | affects binding|decreases reaction | 10344530 |
| D010100 | Oxygen | Oxygen results in decreased expression of ADRB2 protein | decreases expression | 19098126 |
| D010126 | Ozone | ADRB2 protein affects the susceptibility to Ozone | affects response to substance | 10926562 |
| D010126 | Ozone | [Ozone co-treated with Chlorine] affects the expression of ADRB2 mRNA | affects cotreatment|affects expression | 18636392 |
| D037342 | Pertussis Toxin | Pertussis Toxin promotes the reaction [[salmeterol binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine] | affects binding|decreases response to substance|increases activity|increases reaction | 16474418 |
| D037342 | Pertussis Toxin | Pertussis Toxin promotes the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine] | affects binding|decreases response to substance|increases activity|increases reaction | 16474418 |
| D000527 | Alprostadil | Alprostadil results in increased phosphorylation of ADRB2 protein | increases phosphorylation | 14722251 |
| D010656 | Phenylephrine | CGP 20712A inhibits the reaction [[Fenoterol binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine] | affects binding|decreases reaction|decreases response to substance|increases activity | 16474418 |
| D010656 | Phenylephrine | CGP 20712A inhibits the reaction [[salmeterol binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine] | affects binding|decreases reaction|decreases response to substance|increases activity | 16474418 |
| D010656 | Phenylephrine | CGP 20712A inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine] | affects binding|decreases reaction|decreases response to substance|increases activity | 16474418 |
| D010656 | Phenylephrine | [Fenoterol binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine | affects binding|decreases response to substance|increases activity | 16474418 |
| D010656 | Phenylephrine | Pertussis Toxin promotes the reaction [[salmeterol binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine] | affects binding|decreases response to substance|increases activity|increases reaction | 16474418 |
| D010656 | Phenylephrine | Pertussis Toxin promotes the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine] | affects binding|decreases response to substance|increases activity|increases reaction | 16474418 |
| D010656 | Phenylephrine | [salmeterol binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine | affects binding|decreases response to substance|increases activity | 16474418 |
| D010656 | Phenylephrine | [Terbutaline binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine | affects binding|decreases response to substance|increases activity | 16474418 |
| D010852 | Picrotoxin | Picrotoxin results in increased expression of ADRB2 mRNA | increases expression | 15170462 |
| D010869 | Pindolol | Pindolol results in decreased expression of ADRB2 protein | decreases expression | 2175014 |
| C006253 | pirinixic acid | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of ADRB2 mRNA | affects binding|decreases expression|increases activity | 19710929 |
| C006253 | pirinixic acid | pirinixic acid results in increased expression of ADRB2 mRNA | increases expression | 18445702 |
| D011188 | Potassium | [[Forskolin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of [ADRB1 protein binds to ADRB2 protein]] affects the reaction [KCNH2 protein results in increased transport of Potassium] | affects binding|affects cotreatment|affects reaction|increases activity|increases transport | 19419905 |
| D011188 | Potassium | [Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Potassium | affects binding|increases abundance|increases activity | 17292646 |
| D017265 | Procaterol | Procaterol binds to and results in increased activity of ADRB2 protein | affects binding|increases activity | 12606629 |
| D011374 | Progesterone | Progesterone results in increased expression of ADRB2 mRNA | increases expression | 15985637 |
| D011433 | Propranolol | Propranolol binds to and results in decreased activity of ADRB2 protein | affects binding|decreases activity | 10952688 |
| D011433 | Propranolol | Propranolol inhibits the reaction [Albuterol binds to and results in increased activity of ADRB2 protein] | affects binding|decreases reaction|increases activity | 12920204 |
| D011433 | Propranolol | Propranolol inhibits the reaction [[Albuterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 10952688 |
| D011433 | Propranolol | Propranolol inhibits the reaction [Epinephrine binds to and results in increased activity of ADRB2 protein] | affects binding|decreases reaction|increases activity | 12920204 |
| D011433 | Propranolol | Propranolol inhibits the reaction [[Epinephrine binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| D011433 | Propranolol | Propranolol inhibits the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein] | affects binding|decreases reaction|increases activity | 12920204 |
| D011433 | Propranolol | Propranolol inhibits the reaction [[Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| D011433 | Propranolol | Propranolol inhibits the reaction [Terbutaline binds to and results in increased activity of ADRB2 protein] | affects binding|decreases reaction|increases activity | 12920204 |
| D011433 | Propranolol | Propranolol inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| D011433 | Propranolol | Propranolol results in decreased expression of ADRB2 mRNA | decreases expression | 15603589 |
| D011433 | Propranolol | Propranolol binds to and results in decreased activity of ADRB2 protein | affects binding|decreases activity | 17718540 15710352 |
| D011433 | Propranolol | Propranolol inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 17718540 |
| C089730 | rosiglitazone | [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADRB2 mRNA | affects cotreatment|increases expression | 16054899 |
| C057823 | salmeterol | [salmeterol binds to ADRB2 protein] which results in increased expression of CFTR protein | affects binding|increases expression | 12621035 |
| C057823 | salmeterol | salmeterol binds to and results in increased activity of ADRB2 protein | affects binding|increases activity | 10516654 |
| C057823 | salmeterol | [salmeterol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP | affects binding|increases abundance|increases activity | 10516654 |
| C057823 | salmeterol | [salmeterol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein | affects binding|increases activity|increases phosphorylation | 16980553 |
| C057823 | salmeterol | [salmeterol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein | affects binding|increases activity|increases phosphorylation | 16980553 |
| C057823 | salmeterol | salmeterol results in decreased expression of ADRB2 protein | decreases expression | 16980553 |
| C057823 | salmeterol | salmeterol results in increased phosphorylation of ADRB2 protein | increases phosphorylation | 14722251 |
| C057823 | salmeterol | salmeterol binds to and results in increased activity of ADRB2 protein | affects binding|increases activity | 20061444 |
| C057823 | salmeterol | CGP 20712A inhibits the reaction [[salmeterol binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine] | affects binding|decreases reaction|decreases response to substance|increases activity | 16474418 |
| C057823 | salmeterol | Pertussis Toxin promotes the reaction [[salmeterol binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine] | affects binding|decreases response to substance|increases activity|increases reaction | 16474418 |
| C057823 | salmeterol | salmeterol binds to and results in increased activity of ADRB2 protein | affects binding|increases activity | 16474418 |
| C057823 | salmeterol | [salmeterol binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine | affects binding|decreases response to substance|increases activity | 16474418 |
| C057823 | salmeterol | salmeterol binds to and results in increased activity of ADRB2 protein | affects binding|increases activity | 12621035 |
| D022621 | Shiga Toxin | ADRB2 protein affects the reaction [Shiga Toxin results in increased expression of TNF mRNA] | affects reaction|increases expression | 11675405 |
| D022621 | Shiga Toxin | ADRB2 protein promotes the reaction [Shiga Toxin results in increased activity of MAPK1 protein] | increases activity|increases reaction | 11675405 |
| D022621 | Shiga Toxin | ADRB2 protein promotes the reaction [Shiga Toxin results in increased activity of MAPK3 protein] | increases activity|increases reaction | 11675405 |
| D022621 | Shiga Toxin | ADRB2 protein results in decreased susceptibility to Shiga Toxin | decreases response to substance | 11675405 |
| D022641 | Shiga Toxin 2 | [Terbutaline results in increased activity of ADRB2 protein] inhibits the reaction [Shiga Toxin 2 results in increased activity of CASP3 protein] | decreases reaction|increases activity | 12826277 |
| D022641 | Shiga Toxin 2 | [Terbutaline results in increased activity of ADRB2 protein] inhibits the reaction [Shiga Toxin 2 results in increased activity of CASP7 protein] | decreases reaction|increases activity | 12826277 |
| D022641 | Shiga Toxin 2 | [Terbutaline results in increased activity of ADRB2 protein] inhibits the reaction [Shiga Toxin 2 results in increased activity of MAPK1 protein] | decreases reaction|increases activity | 12826277 |
| D022641 | Shiga Toxin 2 | [Terbutaline results in increased activity of ADRB2 protein] inhibits the reaction [Shiga Toxin 2 results in increased activity of MAPK3 protein] | decreases reaction|increases activity | 12826277 |
| D012964 | Sodium | [Terbutaline results in increased activity of ADRB2 protein] which results in increased transport of Sodium | increases activity|increases transport | 20054151 |
| D014284 | Triiodothyronine | bicalutamide inhibits the reaction [Triiodothyronine results in increased expression of ADRB2 protein] | decreases reaction|increases expression | 18454446 |
| D014284 | Triiodothyronine | Triiodothyronine results in increased expression of ADRB2 mRNA | increases expression | 18454446 |
| D014284 | Triiodothyronine | Triiodothyronine results in increased expression of ADRB2 protein | increases expression | 18454446 |
| D013726 | Terbutaline | ADRB2 gene polymorphism affects the reaction [Terbutaline results in increased metabolism of Lipids] | affects reaction|increases metabolic processing | 11429395 |
| D013726 | Terbutaline | ADRB2 gene polymorphism affects the susceptibility to Terbutaline | affects response to substance | 16395068 |
| D013726 | Terbutaline | ADRB2 protein affects the susceptibility to Terbutaline | affects response to substance | 16153394 |
| D013726 | Terbutaline | ADRB2 protein promotes the reaction [Terbutaline promotes the reaction [Lipopolysaccharides results in increased expression of IL8 protein]] | increases expression|increases reaction | 9258252 |
| D013726 | Terbutaline | ADRB2 protein promotes the reaction [Terbutaline results in decreased activity of NFKB1 protein] | decreases activity|increases reaction | 11675405 |
| D013726 | Terbutaline | ADRB2 protein promotes the reaction [Terbutaline results in increased metabolism of Lipids] | increases metabolic processing|increases reaction | 11429395 |
| D013726 | Terbutaline | ADRB2 protein promotes the reaction [Terbutaline results in increased secretion of GAST protein] | increases reaction|increases secretion | 9277405 |
| D013726 | Terbutaline | ADRB2 protein results in increased susceptibility to Terbutaline | increases response to substance | 16395068 |
| D013726 | Terbutaline | Atenolol inhibits the reaction [Terbutaline binds to and results in increased activity of ADRB2 protein] | affects binding|decreases reaction|increases activity | 12920204 |
| D013726 | Terbutaline | Atenolol inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| D013726 | Terbutaline | ICI 118551 inhibits the reaction [Terbutaline binds to and results in increased activity of ADRB2 protein] | affects binding|decreases reaction|increases activity | 12920204 |
| D013726 | Terbutaline | ICI 118551 inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| D013726 | Terbutaline | Propranolol inhibits the reaction [Terbutaline binds to and results in increased activity of ADRB2 protein] | affects binding|decreases reaction|increases activity | 12920204 |
| D013726 | Terbutaline | Propranolol inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 12920204 |
| D013726 | Terbutaline | Terbutaline binds to and results in increased activity of ADRB2 protein | affects binding|increases activity | 12826277 16024912 10516654 11753577 10952688 16395068 12920204 16648137 17292646 10229127 |
| D013726 | Terbutaline | [Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP | affects binding|increases abundance|increases activity | 12920204 10516654 |
| D013726 | Terbutaline | [Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Potassium | affects binding|increases abundance|increases activity | 17292646 |
| D013726 | Terbutaline | [Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein | affects binding|increases activity|increases phosphorylation | 16980553 |
| D013726 | Terbutaline | [Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein | affects binding|increases activity|increases phosphorylation | 16980553 |
| D013726 | Terbutaline | Terbutaline results in decreased expression of ADRB2 protein | decreases expression | 16980553 1280742 |
| D013726 | Terbutaline | [Terbutaline results in increased activity of ADRB2 protein] inhibits the reaction [Shiga Toxin 2 results in increased activity of CASP3 protein] | decreases reaction|increases activity | 12826277 |
| D013726 | Terbutaline | [Terbutaline results in increased activity of ADRB2 protein] inhibits the reaction [Shiga Toxin 2 results in increased activity of CASP7 protein] | decreases reaction|increases activity | 12826277 |
| D013726 | Terbutaline | [Terbutaline results in increased activity of ADRB2 protein] inhibits the reaction [Shiga Toxin 2 results in increased activity of MAPK1 protein] | decreases reaction|increases activity | 12826277 |
| D013726 | Terbutaline | [Terbutaline results in increased activity of ADRB2 protein] inhibits the reaction [Shiga Toxin 2 results in increased activity of MAPK3 protein] | decreases reaction|increases activity | 12826277 |
| D013726 | Terbutaline | Terbutaline results in increased phosphorylation of ADRB2 protein | increases phosphorylation | 16980553 14722251 |
| D013726 | Terbutaline | ADRB2 protein promotes the reaction [Terbutaline results in increased secretion of SFTPB protein] | increases reaction|increases secretion | 14565945 |
| D013726 | Terbutaline | ADRB2 protein promotes the reaction [Terbutaline results in increased secretion of SFTPC protein] | increases reaction|increases secretion | 14565945 |
| D013726 | Terbutaline | Terbutaline binds to and results in increased activity of ADRB2 protein | affects binding|increases activity | 20061444 17430990 |
| D013726 | Terbutaline | ADRB2 protein promotes the reaction [Terbutaline inhibits the reaction [Lipopolysaccharides results in increased activity of MAPK1 protein]] | decreases reaction|increases activity|increases reaction | 10469353 |
| D013726 | Terbutaline | ADRB2 protein promotes the reaction [Terbutaline inhibits the reaction [Lipopolysaccharides results in increased activity of MAPK3 protein]] | decreases reaction|increases activity|increases reaction | 10469353 |
| D013726 | Terbutaline | ADRB2 protein promotes the reaction [Terbutaline inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]] | decreases reaction|increases expression|increases reaction | 11096136 |
| D013726 | Terbutaline | ADRB2 protein promotes the reaction [Terbutaline inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]] | decreases reaction|increases expression|increases reaction | 11096136 |
| D013726 | Terbutaline | ADRB2 protein promotes the reaction [Terbutaline inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]] | decreases reaction|increases expression|increases reaction | 11096136 10857765 |
| D013726 | Terbutaline | ADRB2 protein promotes the reaction [Terbutaline promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]] | increases expression|increases reaction | 11096136 |
| D013726 | Terbutaline | CGP 20712A inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine] | affects binding|decreases reaction|decreases response to substance|increases activity | 16474418 |
| D013726 | Terbutaline | ICI 118551 inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in decreased uptake of Levodopa] | affects binding|decreases reaction|decreases uptake|increases activity | 10894789 |
| D013726 | Terbutaline | ICI 118551 inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Dopamine] | affects binding|decreases reaction|increases abundance|increases activity | 10894789 |
| D013726 | Terbutaline | ICI 118551 inhibits the reaction [Terbutaline results in increased activity of ADRB2 protein] | decreases reaction|increases activity | 20054151 |
| D013726 | Terbutaline | Pertussis Toxin promotes the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine] | affects binding|decreases response to substance|increases activity|increases reaction | 16474418 |
| D013726 | Terbutaline | Terbutaline binds to ADRB2 protein | affects binding | 19098126 |
| D013726 | Terbutaline | Terbutaline binds to and results in increased activity of ADRB2 protein | affects binding|increases activity | 10094932 11713096 10192281 16474418 11096136 10372813 10894789 15467267 |
| D013726 | Terbutaline | [Terbutaline binds to and results in increased activity of ADRB2 protein] which affects the abundance of Calcium | affects abundance|affects binding|increases activity | 10372813 |
| D013726 | Terbutaline | [Terbutaline binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine | affects binding|decreases response to substance|increases activity | 16474418 |
| D013726 | Terbutaline | [Terbutaline binds to and results in increased activity of ADRB2 protein] which results in decreased uptake of Levodopa | affects binding|decreases uptake|increases activity | 10894789 |
| D013726 | Terbutaline | [Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Dopamine | affects binding|increases abundance|increases activity | 10894789 |
| D013726 | Terbutaline | [Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased expression of TNF protein | affects binding|increases activity|increases expression | 10094932 |
| D013726 | Terbutaline | Terbutaline results in increased activity of ADRB2 protein | increases activity | 20054151 11164953 |
| D013726 | Terbutaline | [Terbutaline results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP | increases abundance|increases activity | 10857765 |
| D013726 | Terbutaline | [Terbutaline results in increased activity of ADRB2 protein] which results in increased secretion of Histamine | increases activity|increases secretion | 11164953 |
| D013726 | Terbutaline | [Terbutaline results in increased activity of ADRB2 protein] which results in increased transport of Chlorides | increases activity|increases transport | 20054151 |
| D013726 | Terbutaline | [Terbutaline results in increased activity of ADRB2 protein] which results in increased transport of Sodium | increases activity|increases transport | 20054151 |
| D013726 | Terbutaline | Propranolol inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP] | affects binding|decreases reaction|increases abundance|increases activity | 17718540 |
| D013726 | Terbutaline | Terbutaline binds to and results in increased activity of ADRB2 protein | affects binding|increases activity | 17718540 17400887 17480040 |
| D013726 | Terbutaline | [Terbutaline binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP | affects binding|increases abundance|increases activity | 17718540 17480040 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of ADRB2 mRNA | increases expression | 19933214 |
| D013755 | Tetradecanoylphorbol Acetate | Tetradecanoylphorbol Acetate results in increased phosphorylation of ADRB2 protein | increases phosphorylation | 14722251 |
| D014028 | Tobacco Smoke Pollution | Tobacco Smoke Pollution results in increased expression of ADRB2 mRNA | increases expression | 18087596 |
| C010809 | tulobuterol | tulobuterol binds to and results in increased activity of ADRB2 protein | affects binding|increases activity | 17364588 |
| D015032 | Zinc | Zinc binds to and results in increased activity of ADRB2 protein | affects binding|increases activity | 16567806 |
| D015032 | Zinc | Zinc promotes the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein] | affects binding|increases activity|increases reaction | 11752207 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000014 | Abnormalities, Drug-Induced | Terbutaline | 6.14 | 14610225 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Tetrachlorodibenzodioxin | 6.14 | 15322242 11752688 14514962 | |
| MESH:D000138 | Acidosis | Ammonium Chloride | 2.74 | 18287403 | |
| MESH:D000152 | Acne Vulgaris | Ethinyl Estradiol | 3.10 | 17505938 | |
| MESH:D000169 | Acrodermatitis | Zinc | 4.57 | 17190629 16889938 17202136 | |
| MESH:D055371 | Acute Lung Injury | Chlorine | 20.45 | 20601635 | |
| MESH:D055371 | Acute Lung Injury | Lipopolysaccharides | 20.45 | 11850527 18653653 | |
| MESH:D055371 | Acute Lung Injury | Nickel | 20.45 | 16166738 | |
| MESH:D055371 | Acute Lung Injury | Oxygen | 20.45 | 16759491 | |
| MESH:D055371 | Acute Lung Injury | pirinixic acid | 20.45 | 18653653 | |
| MESH:D000230 | Adenocarcinoma | Doxorubicin | 3.41 | 17418594 | |
| MESH:D000230 | Adenocarcinoma | Ethinyl Estradiol | 3.41 | 14692618 | |
| MESH:D002282 | Adenocarcinoma, Bronchiolo-Alveolar | Tobacco Smoke Pollution | 4.69 | 15814487 | |
| MESH:D018248 | Adenoma, Liver Cell | DDT | 12.71 | 12597452 | |
| MESH:D018248 | Adenoma, Liver Cell | pirinixic acid | 12.71 | 16434500 | |
| MESH:D018248 | Adenoma, Liver Cell | Tetrachlorodibenzodioxin | 12.71 | 16835633 | |
| MESH:D000382 | Agricultural Workers' Diseases | Chlorpyrifos | 9.97 | 16611668 17119214 11874814 | |
| MESH:D000382 | Agricultural Workers' Diseases | DDT | 9.97 | 16487989 12584743 | |
| MESH:D000382 | Agricultural Workers' Diseases | Diazinon | 9.97 | 16487989 | |
| MESH:D000419 | Albuminuria | Doxorubicin | 3.75 | 21441931 | |
| MESH:D000544 | Alzheimer Disease | Copper | 9.52 | 16866297 17119284 16410023 16886094 16962711 16325427 | |
| MESH:D000544 | Alzheimer Disease | Nitric Oxide | 9.52 | 17556102 | |
| MESH:D000544 | Alzheimer Disease | Ozone | 9.52 | 15513908 | |
| MESH:D000544 | Alzheimer Disease | rosiglitazone | 9.52 | 19621015 | |
| MESH:D000544 | Alzheimer Disease | Zinc | 9.52 | 17119284 16325427 16580781 16410023 | |
| MESH:D000686 | Amyloidosis | Terbutaline | 4.84 | 7986221 | |
| MESH:D000690 | Amyotrophic Lateral Sclerosis | Copper | 3.72 | 10694572 | |
| MESH:D000740 | Anemia | Tetrachlorodibenzodioxin | 2.22 | 11748828 | |
| MESH:D018798 | Anemia, Iron-Deficiency | Copper | 4.14 | 16614410 | |
| MESH:D000755 | Anemia, Sickle Cell | Zinc | 4.11 | 16916123 | |
| MESH:D000799 | Angioedema | salmeterol | 5.45 | 10982225 | |
| MESH:D000860 | Anoxia | Oxygen | 4.23 | 20872349 | |
| MESH:D001145 | Arrhythmias, Cardiac | Amiodarone | 6.72 | 20041841 18218290 18057881 | |
| MESH:D001145 | Arrhythmias, Cardiac | Phenylephrine | 6.72 | 17460149 | |
| MESH:D001161 | Arteriosclerosis | Ethinyl Estradiol | 2.66 | 11256880 | |
| MESH:D001169 | Arthritis, Experimental | Dexamethasone | 5.46 | 17659584 | |
| MESH:D001169 | Arthritis, Experimental | Ethinyl Estradiol | 5.46 | 15885639 | |
| MESH:D001172 | Arthritis, Rheumatoid | Ozone | 4.05 | 15570426 | |
| MESH:D001172 | Arthritis, Rheumatoid | Tobacco Smoke Pollution | 4.05 | 19898480 | |
| MESH:D001249 | Asthma | marker/mechanism | |||
| MESH:D001249 | Asthma | Albuterol | 24.35 | 11991558 9949315 | |
| MESH:D001249 | Asthma | Beclomethasone | 24.35 | 12114351 8762487 | |
| MESH:D001249 | Asthma | Budesonide | 24.35 | 20004779 10893010 15136378 18489783 15572850 12604023 12113382 | |
| MESH:D001249 | Asthma | formoterol | 24.35 | 12113382 10967152 | |
| MESH:D001249 | Asthma | Histamine | 24.35 | 16387687 | |
| MESH:D001249 | Asthma | Ozone | 24.35 | 17854713 16373670 | |
| MESH:D001249 | Asthma | salmeterol | 24.35 | 10359889 11694805 | |
| MESH:D001249 | Asthma | tulobuterol | 24.35 | 15212190 15007912 | |
| MESH:D001249 | Asthma | Zinc | 24.35 | 17085522 | |
| MESH:D001250 | Asthma, Exercise-Induced | salmeterol | 5.29 | 10984370 | |
| MESH:D050197 | Atherosclerosis | Oxygen | 3.27 | 16391483 | |
| MESH:D001281 | Atrial Fibrillation | Amiodarone | 3.25 | 18651412 19698954 | |
| MESH:D001321 | Autistic Disorder | marker/mechanism | 17199132 | ||
| MESH:D001321 | Autistic Disorder | Norepinephrine | 2.57 | 8570775 | |
| MESH:D001321 | Autistic Disorder | Propranolol | 2.57 | 18766980 | |
| MESH:D001321 | Autistic Disorder | Terbutaline | 2.57 | 16417856 17400887 | |
| MESH:D001778 | Blood Coagulation Disorders | Amiodarone | 10.98 | 19483382 | |
| MESH:D001778 | Blood Coagulation Disorders | pirinixic acid | 10.98 | 19483382 | |
| MESH:D001778 | Blood Coagulation Disorders | Tetrachlorodibenzodioxin | 10.98 | 12125929 | |
| MESH:D001836 | Body Weight Changes | Tetrachlorodibenzodioxin | 2.95 | 15340226 | |
| MESH:D001848 | Bone Diseases, Developmental | Tetrachlorodibenzodioxin | 2.18 | 15746008 | |
| MESH:D019046 | Bone Marrow Neoplasms | Doxorubicin | 3.86 | 14601052 | |
| MESH:D001919 | Bradycardia | Isoproterenol | 13.14 | 6740701 | |
| MESH:D001919 | Bradycardia | Phenylephrine | 13.14 | 15306635 | |
| MESH:D001919 | Bradycardia | Propranolol | 13.14 | 6740701 | |
| MESH:D020201 | Brain Hemorrhage, Traumatic | Progesterone | 4.49 | 17868700 | |
| MESH:D001930 | Brain Injuries | Progesterone | 8.37 | 15845082 15380490 15665606 | |
| MESH:D001930 | Brain Injuries | Zinc | 8.37 | 17109824 | |
| MESH:D001932 | Brain Neoplasms | Copper | 6.77 | 17079463 | |
| MESH:D001932 | Brain Neoplasms | Doxorubicin | 6.77 | 17150277 | |
| MESH:D001943 | Breast Neoplasms | bexarotene | 8.84 | 16344269 16818667 | |
| MESH:D001943 | Breast Neoplasms | Calcitriol | 8.84 | 11237771 | |
| MESH:D001943 | Breast Neoplasms | Cobalt | 8.84 | 15986119 | |
| MESH:D001943 | Breast Neoplasms | Copper | 8.84 | 15986119 17079463 | |
| MESH:D001943 | Breast Neoplasms | DDT | 8.84 | 12709520 16792888 | |
| MESH:D001943 | Breast Neoplasms | decitabine | 8.84 | 19208741 18320071 | |
| MESH:D001943 | Breast Neoplasms | Dieldrin | 8.84 | 11859874 15770527 | |
| MESH:D001943 | Breast Neoplasms | Doxorubicin | 8.84 | 16826403 15567936 18234424 16264153 15993339 15136595 16115903 15634643 15692762 17426702 18382427 16322301 17369602 18695136 11325840 16935488 17983394 16595493 15994142 15939500 16096432 19526202 18628466 15668708 | |
| MESH:D001943 | Breast Neoplasms | Nickel | 8.84 | 15986119 | |
| MESH:D001943 | Breast Neoplasms | Nitric Oxide | 8.84 | 15631943 | |
| MESH:D001943 | Breast Neoplasms | Oxygen | 8.84 | 17263869 | |
| MESH:D001943 | Breast Neoplasms | Progesterone | 8.84 | 17614352 15562024 16175315 | |
| MESH:D001943 | Breast Neoplasms | Tetrachlorodibenzodioxin | 8.84 | 20435547 | |
| MESH:D016535 | Bronchial Hyperreactivity | Methacholine Compounds | 7.30 | 12388339 | |
| MESH:D016535 | Bronchial Hyperreactivity | Ozone | 7.30 | 15516495 19059883 17626835 14754758 16777450 18417511 18315731 | |
| MESH:D001986 | Bronchial Spasm | Histamine | 4.98 | 18298128 | |
| MESH:D029481 | Bronchitis, Chronic | salmeterol | 5.71 | 17687719 | |
| MESH:D002100 | Cachexia | Ozone | 3.91 | 16183385 | |
| MESH:D019559 | Capillary Leak Syndrome | Terbutaline | 5.02 | 9428835 11713377 | |
| MESH:D002276 | Carcinoid Tumor | Doxorubicin | 3.97 | 16051944 | |
| MESH:D002277 | Carcinoma | Tetrachlorodibenzodioxin | 2.13 | 16835633 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Aflatoxin B1 | 3.70 | 21507988 12619106 12907637 | |
| MESH:D006528 | Carcinoma, Hepatocellular | DDT | 3.70 | 12597452 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Doxorubicin | 3.70 | 18059187 16234567 16023760 17876044 | |
| MESH:D002289 | Carcinoma, Non-Small-Cell Lung | bexarotene | 4.75 | 16247446 | |
| MESH:D002289 | Carcinoma, Non-Small-Cell Lung | Tobacco Smoke Pollution | 4.75 | 11212258 | |
| MESH:D002292 | Carcinoma, Renal Cell | Doxorubicin | 2.70 | 1485588 16201981 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Calcitriol | 13.64 | 11237771 | |
| MESH:D002294 | Carcinoma, Squamous Cell | decitabine | 13.64 | 19215824 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Doxorubicin | 13.64 | 6189445 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Tetradecanoylphorbol Acetate | 13.64 | 18922899 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Tobacco Smoke Pollution | 13.64 | 11212258 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Zinc | 13.64 | 16543248 | |
| MESH:D006332 | Cardiomegaly | Atenolol | 24.20 | 15969258 | |
| MESH:D006332 | Cardiomegaly | Copper | 24.20 | 17327471 | |
| MESH:D006332 | Cardiomegaly | Doxazosin | 24.20 | 15969258 | |
| MESH:D006332 | Cardiomegaly | Isoproterenol | 24.20 | 7544033 11179087 | |
| MESH:D006332 | Cardiomegaly | Norepinephrine | 24.20 | 11179087 | |
| MESH:D006332 | Cardiomegaly | Phenylephrine | 24.20 | 17287366 17124262 16170337 15728586 11754973 11179087 | |
| MESH:D006332 | Cardiomegaly | Tetrachlorodibenzodioxin | 24.20 | 18850075 16120746 18670907 | |
| MESH:D009202 | Cardiomyopathies | Doxorubicin | 2.94 | 17928571 17924179 16952015 16612575 18627295 17308081 16651473 16242529 17351982 16455267 15792986 17519947 17974986 17007740 16278810 17329180 17382496 17131338 15811867 16364871 15476868 16109756 15505089 16269455 16731534 | |
| MESH:D002311 | Cardiomyopathy, Dilated | Amiodarone | 4.71 | 15710769 19225199 | |
| MESH:D002311 | Cardiomyopathy, Dilated | Doxorubicin | 4.71 | 16243910 17334414 | |
| MESH:D002318 | Cardiovascular Diseases | Zinc | 3.06 | 16936243 | |
| MESH:D002341 | Carotid Artery Thrombosis | Amiodarone | 4.26 | 18974383 | |
| MESH:D002375 | Catalepsy | Norepinephrine | 4.71 | 8216760 | |
| MESH:D002471 | Cell Transformation, Neoplastic | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | 4.53 | 20889678 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Cyclosporine | 4.53 | 12371664 | |
| MESH:D018281 | Cholangiocarcinoma | Tetrachlorodibenzodioxin | 2.45 | 16835633 | |
| MESH:D002779 | Cholestasis | Cyclosporine | 13.95 | 19486331 | |
| MESH:D002779 | Cholestasis | Ethinyl Estradiol | 13.95 | 17110522 16919318 17333356 11677210 15861022 17681005 16105132 | |
| MESH:D002779 | Cholestasis | Nitric Oxide | 13.95 | 16919318 | |
| MESH:D002779 | Cholestasis | pirinixic acid | 13.95 | 19176532 | |
| MESH:D002972 | Cleft Palate | Tetrachlorodibenzodioxin | 1.69 | 15340226 8697196 12621046 16354765 15668235 | |
| MESH:D003110 | Colonic Neoplasms | Butyrates | 4.62 | 15936596 | |
| MESH:D003110 | Colonic Neoplasms | decitabine | 4.62 | 17616700 | |
| MESH:D003110 | Colonic Neoplasms | Dexamethasone | 4.62 | 15824018 | |
| MESH:D015179 | Colorectal Neoplasms | Azacitidine | 2.94 | 19934284 | |
| MESH:D015179 | Colorectal Neoplasms | decitabine | 2.94 | 18981723 | |
| MESH:D015179 | Colorectal Neoplasms | Doxorubicin | 2.94 | 18802399 18259882 | |
| MESH:D000013 | Congenital Abnormalities | DDT | 7.08 | 15095906 | |
| MESH:D000013 | Congenital Abnormalities | Tetrachlorodibenzodioxin | 7.08 | 14669216 17141729 | |
| MESH:D003371 | Cough | Terbutaline | 4.73 | 19679606 | |
| MESH:D019465 | Craniofacial Abnormalities | Dexamethasone | 3.09 | 17728286 | |
| MESH:D019465 | Craniofacial Abnormalities | Tetrachlorodibenzodioxin | 3.09 | 15322242 20055451 10048152 | |
| MESH:D019465 | Craniofacial Abnormalities | Zinc | 3.09 | 19302082 | |
| MESH:D015140 | Dementia, Vascular | Nitric Oxide | 5.13 | 17556102 | |
| MESH:D017449 | Dermatitis, Allergic Contact | Dexamethasone | 4.90 | 12438553 | |
| MESH:D017449 | Dermatitis, Allergic Contact | Nickel | 4.90 | 19470301 17244072 17100760 | |
| MESH:D003876 | Dermatitis, Atopic | pirinixic acid | 1.97 | 18249437 | |
| MESH:D003877 | Dermatitis, Contact | Nickel | 3.87 | 2952479 | |
| MESH:D003920 | Diabetes Mellitus | rosiglitazone | 7.20 | 17446233 | |
| MESH:D003920 | Diabetes Mellitus | Zinc | 7.20 | 16479319 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | rosiglitazone | 3.53 | 12642470 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Tetrachlorodibenzodioxin | 3.53 | 17107852 | |
| MESH:D003929 | Diabetic Neuropathies | Progesterone | 3.68 | 17187935 | |
| MESH:D003967 | Diarrhea | Dexamethasone | 2.94 | 7237001 | |
| MESH:D056486 | Drug-Induced Liver Injury | Amiodarone | 4.36 | 18218290 15265979 | |
| MESH:D056486 | Drug-Induced Liver Injury | Doxorubicin | 4.36 | 17416283 | |
| MESH:D056486 | Drug-Induced Liver Injury | Tetrachlorodibenzodioxin | 4.36 | 20420201 | |
| MESH:D004362 | Drug Toxicity | Doxorubicin | 5.95 | 18602426 | |
| MESH:D004362 | Drug Toxicity | Tetrachlorodibenzodioxin | 5.95 | 11462148 | |
| MESH:D004409 | Dyskinesia, Drug-Induced | Levodopa | 5.53 | 15893579 3690436 | |
| MESH:D004417 | Dyspnea | Albuterol | 28.97 | 20016425 | |
| MESH:D004417 | Dyspnea | Budesonide | 28.97 | 20016425 | |
| MESH:D004417 | Dyspnea | Chlorine | 28.97 | 20016425 | |
| MESH:D004417 | Dyspnea | DDT | 28.97 | 16487989 | |
| MESH:D004417 | Dyspnea | Diazinon | 28.97 | 16487989 | |
| MESH:D004417 | Dyspnea | Oxygen | 28.97 | 20016425 | |
| MESH:D004485 | Eczema | Dexamethasone | 3.67 | 12438553 | |
| MESH:D004487 | Edema | Dexamethasone | 13.89 | 19703484 | |
| MESH:D004487 | Edema | pirinixic acid | 13.89 | 12083418 | |
| MESH:D004487 | Edema | rosiglitazone | 13.89 | 12083418 | |
| MESH:D004487 | Edema | Tetrachlorodibenzodioxin | 13.89 | 11000095 12711302 | |
| MESH:D004487 | Edema | Tetradecanoylphorbol Acetate | 13.89 | 8113982 9599246 7812673 11698051 8273558 15177302 16716910 | |
| MESH:D004489 | Edema, Cardiac | Tetrachlorodibenzodioxin | 3.06 | 15322242 18230668 16714409 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Calcitriol | 10.84 | 15138306 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Ethinyl Estradiol | 10.84 | 12538720 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Progesterone | 10.84 | 17692515 | |
| MESH:D004701 | Endocrine Gland Neoplasms | decitabine | 4.27 | 19294695 | |
| MESH:D016889 | Endometrial Neoplasms | Doxorubicin | 2.87 | 17359293 | |
| MESH:D004715 | Endometriosis | Mifepristone | 11.11 | 16134523 | |
| MESH:D004715 | Endometriosis | Progesterone | 11.11 | 16134523 | |
| MESH:D004715 | Endometriosis | Tetrachlorodibenzodioxin | 11.11 | 9294722 10568697 | |
| MESH:D004719 | Endomyocardial Fibrosis | Doxorubicin | 4.31 | 18037988 | |
| MESH:D019446 | Endotoxemia | Lipopolysaccharides | 3.58 | 15328337 17637181 15821434 | |
| MESH:D004802 | Eosinophilia | Beclomethasone | 7.53 | 10351924 | |
| MESH:D004802 | Eosinophilia | Histamine | 7.53 | 12689652 | |
| MESH:D004827 | Epilepsy | Epinephrine | 6.13 | 821787 | |
| MESH:D004827 | Epilepsy | Norepinephrine | 6.13 | 821787 | |
| MESH:D004938 | Esophageal Neoplasms | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | 3.66 | 20426865 | |
| MESH:D004938 | Esophageal Neoplasms | Zinc | 3.66 | 16543248 | |
| MESH:D005124 | Eye Abnormalities | Tetrachlorodibenzodioxin | 2.36 | 11564622 | |
| MESH:D005234 | Fatty Liver | Amiodarone | 16.81 | 14986274 | |
| MESH:D005234 | Fatty Liver | Cyclosporine | 16.81 | 19224547 | |
| MESH:D005234 | Fatty Liver | Ethinyl Estradiol | 16.81 | 15345470 | |
| MESH:D005234 | Fatty Liver | pirinixic acid | 16.81 | 20131406 19236843 | |
| MESH:D005234 | Fatty Liver | rosiglitazone | 16.81 | 19196556 | |
| MESH:D005313 | Fetal Death | Tetrachlorodibenzodioxin | 2.65 | 11858732 | |
| MESH:D005334 | Fever | Lipopolysaccharides | 3.29 | 9205823 11852909 | |
| MESH:D018222 | Fibromatosis, Aggressive | Doxorubicin | 3.76 | 19069698 | |
| MESH:D005355 | Fibrosis | Albuterol | 14.75 | 15467267 | |
| MESH:D005355 | Fibrosis | Cyclosporine | 14.75 | 12168785 12639820 | |
| MESH:D005355 | Fibrosis | Terbutaline | 14.75 | 15467267 | |
| MESH:D005355 | Fibrosis | Tetrachlorodibenzodioxin | 14.75 | 20067830 | |
| MESH:D005739 | Gas Poisoning | Albuterol | 21.50 | 20016425 | |
| MESH:D005739 | Gas Poisoning | Budesonide | 21.50 | 20016425 | |
| MESH:D005739 | Gas Poisoning | Chlorine | 21.50 | 20016425 | |
| MESH:D005739 | Gas Poisoning | Oxygen | 21.50 | 20016425 | |
| MESH:D005756 | Gastritis | Zinc | 3.96 | 17241300 | |
| MESH:D005885 | Gingival Hyperplasia | Cyclosporine | 3.39 | 8708960 | |
| MESH:D005909 | Glioblastoma | Doxorubicin | 2.77 | 17150277 | |
| MESH:D006058 | Gonadal Disorders | Tetrachlorodibenzodioxin | 3.75 | 10696789 | |
| MESH:D006130 | Growth Disorders | Zinc | 3.37 | 17217573 | |
| MESH:D006261 | Headache | Nitric Oxide | 4.34 | 11554966 11284996 | |
| MESH:D006258 | Head and Neck Neoplasms | decitabine | 5.93 | 19215824 | |
| MESH:D006258 | Head and Neck Neoplasms | Doxorubicin | 5.93 | 15692506 | |
| MESH:D006330 | Heart Defects, Congenital | Tetrachlorodibenzodioxin | 1.83 | 11294989 10048152 | |
| MESH:D006331 | Heart Diseases | Doxorubicin | 2.87 | 16495754 14766674 16244372 16879835 16707910 18006777 16244371 17875725 16144979 16330681 18674790 12587719 17888722 | |
| MESH:D006333 | Heart Failure | Atenolol | 24.64 | 20082655 | |
| MESH:D006333 | Heart Failure | Dobutamine | 24.64 | 17440445 | |
| MESH:D006333 | Heart Failure | Doxorubicin | 24.64 | 17481944 | |
| MESH:D006333 | Heart Failure | Isoproterenol | 24.64 | 18097624 | |
| MESH:D006333 | Heart Failure | pirinixic acid | 24.64 | 20558911 | |
| MESH:D006333 | Heart Failure | Propranolol | 24.64 | 20082655 | |
| MESH:D006333 | Heart Failure | Zinc | 24.64 | 17162251 | |
| MESH:D006335 | Heart Injuries | Zinc | 4.93 | 17074742 | |
| MESH:D016481 | Helicobacter Infections | Zinc | 3.76 | 17241300 | |
| MESH:D006394 | Hemangiosarcoma | Doxorubicin | 3.16 | 15692506 | |
| MESH:D006457 | Hemoglobinuria, Paroxysmal | Cyclosporine | 3.59 | 15720958 | |
| MESH:D006463 | Hemolytic-Uremic Syndrome | Lipopolysaccharides | 8.84 | 16366002 | |
| MESH:D006463 | Hemolytic-Uremic Syndrome | Shiga Toxin 2 | 8.84 | 16366002 | |
| MESH:D006470 | Hemorrhage | Tetrachlorodibenzodioxin | 2.58 | 11000095 | |
| MESH:D006505 | Hepatitis | DDT | 7.50 | 16487989 | |
| MESH:D006505 | Hepatitis | Diazinon | 7.50 | 16487989 | |
| MESH:D006521 | Hepatitis, Chronic | Copper | 4.44 | 17338147 | |
| MESH:D006527 | Hepatolenticular Degeneration | Copper | 8.70 | 17109627 19888908 17276780 16607473 17182432 | |
| MESH:D006527 | Hepatolenticular Degeneration | Zinc | 8.70 | 17276780 | |
| MESH:D006529 | Hepatomegaly | Amiodarone | 18.74 | 15265979 | |
| MESH:D006529 | Hepatomegaly | DDT | 18.74 | 2387028 | |
| MESH:D006529 | Hepatomegaly | pirinixic acid | 18.74 | 16221962 18467677 19772884 19176532 | |
| MESH:D006529 | Hepatomegaly | Propranolol | 18.74 | 16371745 | |
| MESH:D006529 | Hepatomegaly | Tetrachlorodibenzodioxin | 18.74 | 16120746 15340226 12621046 | |
| MESH:D006548 | Hernia, Diaphragmatic | Dexamethasone | 2.71 | 7520565 | |
| MESH:D015658 | HIV Infections | Nickel | 3.32 | 17263646 | |
| MESH:D006689 | Hodgkin Disease | Doxorubicin | 2.73 | 18501091 15147373 17606976 | |
| MESH:D006869 | Hydronephrosis | Tetrachlorodibenzodioxin | 3.20 | 15340226 16959395 18606429 16354765 8697196 | |
| MESH:D006930 | Hyperalgesia | rosiglitazone | 3.25 | 12083418 | |
| MESH:D006937 | Hypercholesterolemia | Amiodarone | 3.13 | 8137927 9751232 | |
| MESH:D006940 | Hyperemia | Nitric Oxide | 4.79 | 11156591 | |
| MESH:D006943 | Hyperglycemia | pirinixic acid | 2.45 | 20558911 | |
| MESH:D020138 | Hyperhomocysteinemia | Levodopa | 4.98 | 16275827 16787708 | |
| MESH:D006949 | Hyperlipidemias | marker/mechanism | 16027735 | ||
| MESH:D006973 | Hypertension | Atenolol | 18.70 | 12717102 12022239 14700505 15188945 15969258 15453913 11910301 15614026 15237695 14597852 19249413 11593098 | |
| MESH:D006973 | Hypertension | Cobalt | 18.70 | 17039479 | |
| MESH:D006973 | Hypertension | Cyclosporine | 18.70 | 10903974 | |
| MESH:D006973 | Hypertension | Dexamethasone | 18.70 | 17042910 | |
| MESH:D006973 | Hypertension | Doxazosin | 18.70 | 15969258 | |
| MESH:D006973 | Hypertension | Phenylephrine | 18.70 | 8949925 12717712 | |
| MESH:D006973 | Hypertension | Tetrachlorodibenzodioxin | 18.70 | 18850075 18670907 | |
| MESH:D006976 | Hypertension, Pulmonary | Nitric Oxide | 3.79 | 15838368 | |
| MESH:D006984 | Hypertrophy | Isoproterenol | 8.50 | 12791704 | |
| MESH:D006984 | Hypertrophy | Phenylephrine | 8.50 | 18502941 12791704 | |
| MESH:D017379 | Hypertrophy, Left Ventricular | Atenolol | 4.96 | 15237695 | |
| MESH:D006985 | Hyperventilation | Terbutaline | 5.26 | 10895896 | |
| MESH:D007008 | Hypokalemia | marker/mechanism | 17292646 | ||
| MESH:D007008 | Hypokalemia | Terbutaline | 5.26 | 17292646 | |
| MESH:D020514 | Hypokalemic Periodic Paralysis | Potassium | 5.03 | 19822448 | |
| MESH:D007021 | Hypospadias | Ethinyl Estradiol | 3.00 | 16945680 16569931 | |
| MESH:D007022 | Hypotension | Dopamine | 20.28 | 6740701 | |
| MESH:D007022 | Hypotension | Epinephrine | 20.28 | 6740701 | |
| MESH:D007022 | Hypotension | Isoproterenol | 20.28 | 6740701 | |
| MESH:D007022 | Hypotension | Norepinephrine | 20.28 | 6740701 | |
| MESH:D007022 | Hypotension | Propranolol | 20.28 | 6740701 | |
| MESH:D007037 | Hypothyroidism | Amiodarone | 3.71 | 17991464 18020914 | |
| MESH:D007077 | Ileal Diseases | 1-Methyl-3-isobutylxanthine | 4.60 | 18306037 | |
| MESH:D020244 | Infarction, Middle Cerebral Artery | Progesterone | 3.59 | 15869954 | |
| MESH:D007247 | Infertility, Female | Dieldrin | 7.73 | 10630421 | |
| MESH:D007247 | Infertility, Female | Ethinyl Estradiol | 7.73 | 12013081 | |
| MESH:D007248 | Infertility, Male | DDT | 11.20 | 17192596 17157474 | |
| MESH:D007248 | Infertility, Male | decitabine | 11.20 | 17581917 | |
| MESH:D007248 | Infertility, Male | Diazinon | 11.20 | 12948887 16466525 | |
| MESH:D007248 | Infertility, Male | Ethinyl Estradiol | 11.20 | 17937319 | |
| MESH:D007249 | Inflammation | Dexamethasone | 19.70 | 8960868 11099482 | |
| MESH:D007249 | Inflammation | Lipopolysaccharides | 19.70 | 9205823 12878042 17255318 17963957 17237260 | |
| MESH:D007249 | Inflammation | Nickel | 19.70 | 16166738 | |
| MESH:D007249 | Inflammation | Progesterone | 19.70 | 15869954 | |
| MESH:D007249 | Inflammation | rosiglitazone | 19.70 | 12083418 | |
| MESH:D007249 | Inflammation | Tetrachlorodibenzodioxin | 19.70 | 12200463 12878042 | |
| MESH:D007249 | Inflammation | Tetradecanoylphorbol Acetate | 19.70 | 7562506 7812673 11698051 8273558 15177302 | |
| MESH:D007249 | Inflammation | Tobacco Smoke Pollution | 19.70 | 18590791 | |
| MESH:D007333 | Insulin Resistance | pirinixic acid | 5.52 | 16306350 | |
| MESH:D007333 | Insulin Resistance | rosiglitazone | 5.52 | 16306350 | |
| MESH:D007410 | Intestinal Diseases | Nitric Oxide | 4.13 | 10210152 11713966 11574821 | |
| MESH:D019189 | Iron Metabolism Disorders | Lipopolysaccharides | 3.86 | 17255318 | |
| MESH:D007511 | Ischemia | Zinc | 3.83 | 16584753 | |
| MESH:D007569 | Jaw Abnormalities | Tetrachlorodibenzodioxin | 2.58 | 16580747 | |
| MESH:D007579 | Jejunal Diseases | 1-Methyl-3-isobutylxanthine | 4.60 | 18306037 | |
| MESH:D007638 | Keratoconjunctivitis Sicca | Cyclosporine | 3.60 | 15604871 | |
| MESH:D007674 | Kidney Diseases | Cyclosporine | 7.04 | 18776723 10903974 8314463 | |
| MESH:D007674 | Kidney Diseases | Doxorubicin | 7.04 | 15699352 15369732 16775033 | |
| MESH:D007674 | Kidney Diseases | Zinc | 7.04 | 16960431 | |
| MESH:D007676 | Kidney Failure, Chronic | Copper | 12.57 | 16518626 | |
| MESH:D007676 | Kidney Failure, Chronic | Doxorubicin | 12.57 | 16707910 | |
| MESH:D007676 | Kidney Failure, Chronic | Zinc | 12.57 | 16518626 | |
| MESH:D007680 | Kidney Neoplasms | Cyclosporine | 2.06 | 12371664 | |
| MESH:D007683 | Kidney Tubular Necrosis, Acute | Calcium | 4.21 | 16316344 | |
| MESH:D007859 | Learning Disorders | Copper | 7.67 | 17134702 | |
| MESH:D007859 | Learning Disorders | DDT | 7.67 | 7589230 | |
| MESH:D007896 | Leishmaniasis | Nitric Oxide | 3.95 | 17218153 | |
| MESH:D053609 | Lethargy | Terbutaline | 5.47 | 10895896 | |
| MESH:D007938 | Leukemia | Azacitidine | 5.13 | 19148494 | |
| MESH:D007938 | Leukemia | decitabine | 5.13 | 19235587 18980019 | |
| MESH:D004915 | Leukemia, Erythroblastic, Acute | Doxorubicin | 4.31 | 16085563 | |
| MESH:D007951 | Leukemia, Myeloid | Azacitidine | 7.41 | 19077051 | |
| MESH:D007951 | Leukemia, Myeloid | decitabine | 7.41 | 17236224 18454857 19117987 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | Azacitidine | 3.55 | 17596541 18720364 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | decitabine | 3.55 | 17679729 18704418 18460780 19010910 18206229 19387464 | |
| MESH:D015477 | Leukemia, Myelomonocytic, Chronic | decitabine | 4.62 | 18055864 | |
| MESH:D054429 | Leukemia, Myelomonocytic, Juvenile | Azacitidine | 4.42 | 19299654 | |
| MESH:D007970 | Leukopenia | Lipopolysaccharides | 3.87 | 15821434 | |
| MESH:D008064 | Lipidoses | Amiodarone | 2.88 | 17567588 15342952 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Dexamethasone | 6.53 | 16718785 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Doxorubicin | 6.53 | 16439617 16595196 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Lipopolysaccharides | 6.53 | 12878042 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | pirinixic acid | 6.53 | 15474484 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | rosiglitazone | 6.53 | 17347453 15980055 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Tetrachlorodibenzodioxin | 6.53 | 12878042 | |
| MESH:D008107 | Liver Diseases | Chlorpyrifos | 3.95 | 15991261 | |
| MESH:D008107 | Liver Diseases | DDT | 3.95 | 15729006 | |
| MESH:D008113 | Liver Neoplasms | Aflatoxin B1 | 12.69 | 9163691 18177683 2125692 15890375 | |
| MESH:D008113 | Liver Neoplasms | Copper | 12.69 | 20302851 | |
| MESH:D008113 | Liver Neoplasms | DDT | 12.69 | 15975961 11948501 | |
| MESH:D008113 | Liver Neoplasms | Dieldrin | 12.69 | 9539021 8742319 | |
| MESH:D008113 | Liver Neoplasms | pirinixic acid | 12.69 | 15890375 16377806 20007298 | |
| MESH:D008113 | Liver Neoplasms | Tetrachlorodibenzodioxin | 12.69 | 16984957 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Aflatoxin B1 | 6.55 | 8603461 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Doxorubicin | 6.55 | 17085340 16842330 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Tetrachlorodibenzodioxin | 6.55 | 12151625 | |
| MESH:D008133 | Long QT Syndrome | Amiodarone | 6.50 | 11989578 15350150 17391786 | |
| MESH:D008133 | Long QT Syndrome | Dobutamine | 6.50 | 19353679 | |
| MESH:D008171 | Lung Diseases | Amiodarone | 9.05 | 12587719 | |
| MESH:D008171 | Lung Diseases | Dobutamine | 9.05 | 16638327 | |
| MESH:D008171 | Lung Diseases | Ozone | 9.05 | 8266340 19066396 | |
| MESH:D017563 | Lung Diseases, Interstitial | Amiodarone | 3.64 | 18516814 | |
| MESH:D008173 | Lung Diseases, Obstructive | Cobalt | 5.05 | 6434250 | |
| MESH:D055370 | Lung Injury | Asbestos, Crocidolite | 19.81 | 17365036 | |
| MESH:D055370 | Lung Injury | Lipopolysaccharides | 19.81 | 21114838 | |
| MESH:D055370 | Lung Injury | Nitric Oxide | 19.81 | 11395602 | |
| MESH:D055370 | Lung Injury | Oxygen | 19.81 | 18339021 | |
| MESH:D055370 | Lung Injury | Ozone | 19.81 | 20417186 | |
| MESH:D008175 | Lung Neoplasms | Aflatoxin B1 | 14.02 | 14755239 | |
| MESH:D008175 | Lung Neoplasms | Azacitidine | 14.02 | 21224363 | |
| MESH:D008175 | Lung Neoplasms | bexarotene | 14.02 | 17849452 | |
| MESH:D008175 | Lung Neoplasms | Budesonide | 14.02 | 12117777 16885199 17163412 | |
| MESH:D008175 | Lung Neoplasms | Dexamethasone | 14.02 | 11195469 15824018 | |
| MESH:D008175 | Lung Neoplasms | Doxorubicin | 14.02 | 17418594 6189445 | |
| MESH:D008175 | Lung Neoplasms | Ozone | 14.02 | 7614698 8597069 | |
| MESH:D008175 | Lung Neoplasms | Tetrachlorodibenzodioxin | 14.02 | 19555203 11884234 | |
| MESH:D008175 | Lung Neoplasms | Tetradecanoylphorbol Acetate | 14.02 | 11807781 | |
| MESH:D008175 | Lung Neoplasms | Tobacco Smoke Pollution | 14.02 | 12111688 11091918 3440675 16288123 | |
| MESH:D008223 | Lymphoma | decitabine | 9.08 | 19470736 | |
| MESH:D008223 | Lymphoma | Doxorubicin | 9.08 | 16098063 | |
| MESH:D008223 | Lymphoma | Nitric Oxide | 9.08 | 16166326 | |
| MESH:D008228 | Lymphoma, Non-Hodgkin | Doxorubicin | 3.10 | 17654614 | |
| MESH:D016399 | Lymphoma, T-Cell | Doxorubicin | 3.76 | 15621674 | |
| MESH:D016410 | Lymphoma, T-Cell, Cutaneous | bexarotene | 4.34 | 11161223 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | bexarotene | 19.56 | 15591091 19196723 19196722 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Corticosterone | 19.56 | 12807724 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Doxorubicin | 19.56 | 15458769 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Progesterone | 19.56 | 17203775 11408345 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | rosiglitazone | 19.56 | 16827153 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Tetradecanoylphorbol Acetate | 19.56 | 8985016 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Zinc | 19.56 | 12773700 | |
| MESH:D008382 | Marfan Syndrome | Atenolol | 5.44 | 19430350 | |
| MESH:D008545 | Melanoma | decitabine | 5.55 | 16505122 17785578 | |
| MESH:D008545 | Melanoma | Doxorubicin | 5.55 | 16827129 | |
| MESH:D008545 | Melanoma | Glucose | 5.55 | 14993021 | |
| MESH:D008545 | Melanoma | Histamine | 5.55 | 17709802 | |
| MESH:D007706 | Menkes Kinky Hair Syndrome | Copper | 5.05 | 17109627 17268249 | |
| MESH:D008654 | Mesothelioma | Asbestos, Crocidolite | 5.03 | 16966607 16166281 18303189 | |
| MESH:D008654 | Mesothelioma | Doxorubicin | 5.03 | 17638057 | |
| MESH:D024821 | Metabolic Syndrome X | rosiglitazone | 3.68 | 17261469 | |
| MESH:D008664 | Metal Metabolism, Inborn Errors | Cyclosporine | 3.94 | 16801185 | |
| MESH:D008679 | Metaplasia | Ozone | 4.26 | 10496685 | |
| MESH:D008881 | Migraine Disorders | Nitric Oxide | 3.66 | 11701602 | |
| MESH:D020326 | Migraine without Aura | Cyclic AMP | 8.55 | 11304026 | |
| MESH:D020326 | Migraine without Aura | Nitric Oxide | 8.55 | 14659530 11304026 | |
| MESH:D028361 | Mitochondrial Diseases | Doxorubicin | 3.74 | 15792986 | |
| MESH:D009006 | Monosomy | Azacitidine | 5.24 | 19299654 | |
| MESH:D009062 | Mouth Neoplasms | Tobacco Smoke Pollution | 3.69 | 15006635 | |
| MESH:D052016 | Mucositis | Doxorubicin | 3.96 | 17415656 | |
| MESH:D009101 | Multiple Myeloma | Azacitidine | 8.64 | 19549372 18443271 | |
| MESH:D009101 | Multiple Myeloma | decitabine | 8.64 | 18172295 | |
| MESH:D009101 | Multiple Myeloma | Dexamethasone | 8.64 | 16118317 15744524 15867202 | |
| MESH:D009135 | Muscular Diseases | pirinixic acid | 2.70 | 16239165 | |
| MESH:D009181 | Mycoses | Amiodarone | 4.06 | 12754197 17974566 | |
| MESH:D009190 | Myelodysplastic Syndromes | Azacitidine | 9.35 | 17596541 18720364 17611569 19805378 | |
| MESH:D009190 | Myelodysplastic Syndromes | decitabine | 9.35 | 16882708 18608210 19157545 19010910 | |
| MESH:D009190 | Myelodysplastic Syndromes | Dexamethasone | 9.35 | 9809623 | |
| MESH:D009203 | Myocardial Infarction | Doxorubicin | 7.08 | 19429709 15857846 | |
| MESH:D009203 | Myocardial Infarction | Isoproterenol | 7.08 | 16584858 19172585 19595682 15740881 16538859 16697266 17052832 | |
| MESH:D009203 | Myocardial Infarction | pirinixic acid | 7.08 | 19151258 | |
| MESH:D017202 | Myocardial Ischemia | marker/mechanism | 9554809 | ||
| MESH:D017202 | Myocardial Ischemia | Dobutamine | 7.11 | 12447174 | |
| MESH:D017202 | Myocardial Ischemia | Tetrachlorodibenzodioxin | 7.11 | 12213967 | |
| MESH:D015428 | Myocardial Reperfusion Injury | Norepinephrine | 6.61 | 15642760 | |
| MESH:D015428 | Myocardial Reperfusion Injury | pirinixic acid | 6.61 | 16411023 | |
| MESH:D009362 | Neoplasm Metastasis | Doxorubicin | 2.55 | 18259882 | |
| MESH:D009369 | Neoplasms | DDT | 7.96 | 8820588 | |
| MESH:D009369 | Neoplasms | decitabine | 7.96 | 19470736 17925555 19116145 | |
| MESH:D009369 | Neoplasms | Dieldrin | 7.96 | 8820588 | |
| MESH:D009369 | Neoplasms | pirinixic acid | 7.96 | 17405874 | |
| MESH:D009376 | Neoplasms, Hormone-Dependent | bexarotene | 3.95 | 19196722 | |
| MESH:D009389 | Neovascularization, Pathologic | Copper | 4.13 | 17308104 | |
| MESH:D009401 | Nephrosis | Doxorubicin | 3.96 | 16636307 16899518 | |
| MESH:D009402 | Nephrosis, Lipoid | Cyclosporine | 3.60 | 17954296 | |
| MESH:D009404 | Nephrotic Syndrome | Cyclosporine | 6.92 | 18481113 19348381 | |
| MESH:D009404 | Nephrotic Syndrome | Doxorubicin | 6.92 | 16889571 15640375 | |
| MESH:D009421 | Nervous System Malformations | Tetrachlorodibenzodioxin | 2.43 | 14600291 | |
| MESH:D009447 | Neuroblastoma | Doxorubicin | 2.77 | 15555623 | |
| MESH:D020258 | Neurotoxicity Syndromes | Chlorpyrifos | 3.56 | 15081274 | |
| MESH:D009765 | Obesity | marker/mechanism | 15687340 | ||
| MESH:D009765 | Obesity | pirinixic acid | 1.55 | 20558911 | |
| MESH:D007752 | Obstetric Labor, Premature | Terbutaline | 5.27 | 14998686 | |
| MESH:D010024 | Osteoporosis | Calcium | 3.22 | 17882678 | |
| MESH:D012516 | Osteosarcoma | Doxorubicin | 3.43 | 15930896 | |
| MESH:D010051 | Ovarian Neoplasms | decitabine | 5.97 | 19331143 19259094 | |
| MESH:D010051 | Ovarian Neoplasms | Mifepristone | 5.97 | 16525653 | |
| MESH:D010051 | Ovarian Neoplasms | Progesterone | 5.97 | 17393432 16525653 | |
| MESH:D010190 | Pancreatic Neoplasms | decitabine | 4.33 | 19294695 | |
| MESH:D010190 | Pancreatic Neoplasms | Tetradecanoylphorbol Acetate | 4.33 | 15976015 | |
| MESH:D016584 | Panic Disorder | Ethinyl Estradiol | 2.91 | 11578682 | |
| MESH:D010212 | Papilloma | Tetradecanoylphorbol Acetate | 3.50 | 18404319 12065085 8330346 18922899 | |
| MESH:D010300 | Parkinson Disease | Dieldrin | 5.10 | 17291500 11445065 11181820 16112328 16809432 | |
| MESH:D010300 | Parkinson Disease | Levodopa | 5.10 | 7566641 19594199 18328768 11432539 20334432 | |
| MESH:D020734 | Parkinsonian Disorders | Levodopa | 4.93 | 8817341 11246459 18722529 | |
| MESH:D010382 | Peliosis Hepatis | Tetrachlorodibenzodioxin | 3.40 | 12520081 | |
| MESH:D010538 | Peritonitis | Ozone | 3.33 | 16369182 | |
| MESH:D003557 | Phyllodes Tumor | Doxorubicin | 4.31 | 17983394 | |
| MESH:D010995 | Pleural Diseases | Asbestos, Crocidolite | 4.08 | 10923243 | |
| MESH:D010997 | Pleural Neoplasms | Doxorubicin | 4.31 | 17638057 | |
| MESH:D011014 | Pneumonia | Lipopolysaccharides | 8.37 | 11605937 12224865 | |
| MESH:D011014 | Pneumonia | Ozone | 8.37 | 18007984 18929643 18381685 | |
| MESH:D011015 | Pneumonia, Aspiration | Nitric Oxide | 4.51 | 18573544 | |
| MESH:D011041 | Poisoning | Diazinon | 3.60 | 17603234 | |
| MESH:D017119 | Porphyria Cutanea Tarda | Tetrachlorodibenzodioxin | 2.77 | 18163543 | |
| MESH:D011230 | Precancerous Conditions | Cyclosporine | 2.51 | 12371664 | |
| MESH:D054198 | Precursor Cell Lymphoblastic Leukemia-Lymphoma | Dexamethasone | 3.01 | 21297632 | |
| MESH:D011225 | Pre-Eclampsia | Zinc | 3.51 | 17114810 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | Tetrachlorodibenzodioxin | 2.38 | 11896295 11118676 11399792 11222880 | |
| MESH:D055728 | Primary Myelofibrosis | decitabine | 3.92 | 17616702 | |
| MESH:D011470 | Prostatic Hyperplasia | Calcitriol | 3.95 | 15572423 | |
| MESH:D011471 | Prostatic Neoplasms | marker/mechanism | 18454446 | ||
| MESH:D011471 | Prostatic Neoplasms | Azacitidine | 2.13 | 18324645 | |
| MESH:D011471 | Prostatic Neoplasms | bicalutamide | 2.13 | 19240160 18487222 17914592 19011039 15638997 | |
| MESH:D011471 | Prostatic Neoplasms | Calcitriol | 2.13 | 16289102 15754350 12479363 16644109 18247401 | |
| MESH:D011471 | Prostatic Neoplasms | Clorgyline | 2.13 | 19691856 | |
| MESH:D011471 | Prostatic Neoplasms | Copper | 2.13 | 17308104 17079463 | |
| MESH:D011471 | Prostatic Neoplasms | DDT | 2.13 | 12584743 | |
| MESH:D011471 | Prostatic Neoplasms | Doxorubicin | 2.13 | 18437689 16888761 16729912 15749863 15897917 16868541 | |
| MESH:D011471 | Prostatic Neoplasms | Zinc | 2.13 | 16700911 16606632 12429649 16517595 | |
| MESH:D011537 | Pruritus | Ethinyl Estradiol | 2.50 | 15861022 16919318 | |
| MESH:D011565 | Psoriasis | Cyclosporine | 1.86 | 16882103 | |
| MESH:D011654 | Pulmonary Edema | Isoproterenol | 8.74 | 10903255 | |
| MESH:D011654 | Pulmonary Edema | Terbutaline | 8.74 | 10903255 | |
| MESH:D011658 | Pulmonary Fibrosis | Amiodarone | 7.10 | 12490602 11597910 12832656 | |
| MESH:D011658 | Pulmonary Fibrosis | Asbestos, Crocidolite | 7.10 | 17322281 17365031 15814490 17975199 | |
| MESH:D011658 | Pulmonary Fibrosis | Cobalt | 7.10 | 6434250 | |
| MESH:D051437 | Renal Insufficiency | Doxorubicin | 3.42 | 17922066 | |
| MESH:D015427 | Reperfusion Injury | pirinixic acid | 1.91 | 19058328 | |
| MESH:D012120 | Respiration Disorders | Chlorine | 4.37 | 18579056 | |
| MESH:D012128 | Respiratory Distress Syndrome, Adult | Dexamethasone | 11.06 | 18379247 11700416 | |
| MESH:D012128 | Respiratory Distress Syndrome, Adult | Oxygen | 11.06 | 17627322 18339021 | |
| MESH:D012128 | Respiratory Distress Syndrome, Adult | Terbutaline | 11.06 | 2878809 | |
| MESH:D012130 | Respiratory Hypersensitivity | Lipopolysaccharides | 3.13 | 10835634 | |
| MESH:D012135 | Respiratory Sounds | Chlorpyrifos | 7.48 | 16611668 17119214 11874814 | |
| MESH:D012135 | Respiratory Sounds | Tobacco Smoke Pollution | 7.48 | 18410779 | |
| MESH:D015619 | Respiratory System Abnormalities | Tetrachlorodibenzodioxin | 3.04 | 18990726 | |
| MESH:D012140 | Respiratory Tract Diseases | Chlorpyrifos | 4.06 | 17119214 16611668 | |
| MESH:D012162 | Retinal Degeneration | Zinc | 3.47 | 16584753 | |
| MESH:D012208 | Rhabdomyosarcoma | decitabine | 3.63 | 19155313 | |
| MESH:D012220 | Rhinitis | Beclomethasone | 7.53 | 10351924 | |
| MESH:D012220 | Rhinitis | Histamine | 7.53 | 12689652 | |
| MESH:D012468 | Salivary Gland Neoplasms | Progesterone | 2.48 | 18045962 | |
| MESH:D012509 | Sarcoma | Doxorubicin | 3.26 | 17710206 15675481 17203757 15625365 16767912 18313854 | |
| MESH:D012512 | Sarcoma, Ewing's | Doxorubicin | 3.46 | 16326096 14601052 | |
| MESH:D012514 | Sarcoma, Kaposi | Doxorubicin | 3.96 | 17846226 | |
| MESH:D012555 | Schistosomiasis mansoni | Nitric Oxide | 4.66 | 9673227 | |
| MESH:D012559 | Schizophrenia | Copper | 2.94 | 16842975 | |
| MESH:C537537 | Segawa syndrome, autosomal recessive | Levodopa | 5.86 | 8817341 | |
| MESH:D012640 | Seizures | Picrotoxin | 3.44 | 8954991 8635557 | |
| MESH:D012729 | Sex Chromosome Aberrations | Chlorpyrifos | 5.25 | 6418539 | |
| MESH:D012772 | Shock, Septic | Terbutaline | 4.67 | 3431524 | |
| OMIM:609620 | SHORT QT SYNDROME 1 | Amiodarone | 4.26 | 18724381 | |
| MESH:D012852 | Sinusitis | Beclomethasone | 9.17 | 7327846 | |
| MESH:D012852 | Sinusitis | Phenylephrine | 9.17 | 7327846 | |
| MESH:D012878 | Skin Neoplasms | Doxorubicin | 12.92 | 15692506 | |
| MESH:D012878 | Skin Neoplasms | Glucose | 12.92 | 14993021 | |
| MESH:D012878 | Skin Neoplasms | Tetrachlorodibenzodioxin | 12.92 | 16192470 | |
| MESH:D012878 | Skin Neoplasms | Tetradecanoylphorbol Acetate | 12.92 | 18404319 11807781 8330346 12065085 8985016 | |
| MESH:D012878 | Skin Neoplasms | Tobacco Smoke Pollution | 12.92 | 18590791 | |
| MESH:D012983 | Soft Tissue Neoplasms | Doxorubicin | 3.76 | 17203757 15625365 16767912 | |
| MESH:D013088 | Spermatocele | Ethinyl Estradiol | 3.10 | 16709447 | |
| MESH:D013119 | Spinal Cord Injuries | Progesterone | 3.46 | 15862959 16503802 | |
| MESH:D013272 | Stomach Diseases | Dexamethasone | 3.50 | 15472012 | |
| MESH:D013274 | Stomach Neoplasms | decitabine | 2.11 | 19037991 | |
| MESH:D013276 | Stomach Ulcer | Amiodarone | 8.00 | 18087811 | |
| MESH:D013276 | Stomach Ulcer | Dexamethasone | 8.00 | 15138204 | |
| MESH:D013276 | Stomach Ulcer | Nitric Oxide | 8.00 | 15138204 | |
| MESH:D013398 | Sudden Infant Death | Oxygen | 4.72 | 12563064 | |
| MESH:D013610 | Tachycardia | Amiodarone | 13.68 | 11238279 | |
| MESH:D013610 | Tachycardia | Norepinephrine | 13.68 | 3261545 | |
| MESH:D013610 | Tachycardia | Terbutaline | 13.68 | 10895896 | |
| MESH:D017180 | Tachycardia, Ventricular | Amiodarone | 3.40 | 19225199 | |
| MESH:D013921 | Thrombocytopenia | Lipopolysaccharides | 3.43 | 15821434 | |
| MESH:D019851 | Thrombophilia | Ethinyl Estradiol | 2.85 | 11994571 | |
| MESH:D013927 | Thrombosis | Ethinyl Estradiol | 2.44 | 15669648 | |
| MESH:D013959 | Thyroid Diseases | Amiodarone | 9.26 | 19731979 | |
| MESH:D013959 | Thyroid Diseases | Tetrachlorodibenzodioxin | 9.26 | 12697716 | |
| MESH:D018382 | Thyroid Hormone Resistance Syndrome | Atenolol | 5.58 | 9349583 | |
| MESH:D013964 | Thyroid Neoplasms | Butyrates | 8.39 | 17967635 | |
| MESH:D013964 | Thyroid Neoplasms | decitabine | 8.39 | 17967635 | |
| MESH:D013964 | Thyroid Neoplasms | Doxorubicin | 8.39 | 16010429 17909728 | |
| MESH:D013971 | Thyrotoxicosis | Amiodarone | 4.05 | 19584973 18020914 | |
| MESH:D014062 | Tongue Neoplasms | Zinc | 3.66 | 16543248 | |
| MESH:D016171 | Torsades de Pointes | Amiodarone | 8.04 | 17467628 11989578 | |
| MESH:D016171 | Torsades de Pointes | Dobutamine | 8.04 | 19353679 | |
| MESH:D001749 | Urinary Bladder Neoplasms | decitabine | 6.13 | 19087683 17616700 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Doxorubicin | 6.13 | 17653716 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Tobacco Smoke Pollution | 6.13 | 12846360 | |
| MESH:D014570 | Urologic Diseases | DDT | 9.75 | 16487989 | |
| MESH:D014570 | Urologic Diseases | Diazinon | 9.75 | 16487989 | |
| MESH:D014581 | Urticaria | Histamine | 7.49 | 18298128 | |
| MESH:D014581 | Urticaria | salmeterol | 7.49 | 10982225 | |
| MESH:D014594 | Uterine Neoplasms | Ethinyl Estradiol | 2.52 | 14692618 | |
| MESH:D014604 | Uveal Neoplasms | decitabine | 4.07 | 17785578 | |
| MESH:D014605 | Uveitis | Cyclosporine | 8.98 | 1336536 | |
| MESH:D014605 | Uveitis | Dexamethasone | 8.98 | 1336536 | |
| MESH:D054079 | Vascular Malformations | Tetrachlorodibenzodioxin | 3.75 | 12125929 | |
| MESH:D020246 | Venous Thrombosis | Ethinyl Estradiol | 2.79 | 14671159 15869587 | |
| MESH:D018487 | Ventricular Dysfunction, Left | Doxorubicin | 7.97 | 17638931 16364871 17678736 17334414 | |
| MESH:D018487 | Ventricular Dysfunction, Left | Isoproterenol | 7.97 | 18097624 | |
| MESH:D020257 | Ventricular Remodeling | Isoproterenol | 4.86 | 18097624 | |
| MESH:D019282 | Wasting Syndrome | Tetrachlorodibenzodioxin | 3.40 | 15886252 | |
| MESH:D014985 | Xerophthalmia | Cyclosporine | 3.60 | 17120751 |
| Pathway ID | Pathway Name |
|---|---|
| KEGG:04020 | Calcium signaling pathway |
| KEGG:04144 | Endocytosis |
| KEGG:04080 | Neuroactive ligand-receptor interaction |
| KEGG:04970 | Salivary secretion |
| REACT:14797 | Signaling by GPCR |
| Releated gene ID | Related gene Name |
|---|---|
| PA24574 | ADH5 |
| PA39 | ADRB2 |
| Releated disease ID | Related disease Name |
|---|---|
| PA443890 | Diabetes Mellitus, Type 2 |
| PA447306 | diabetes mellitus type 2 and obesity |
| PA443421 | Arrhythmias, Cardiac |
| PA443459 | Atrial Fibrillation |
| PA159018367 | Brugada syndrome |
| PA443633 | Cardiomyopathy, Hypertrophic |
| PA444807 | Long QT Syndrome |
| PA445769 | Sudden Infant Death |
| PA445848 | Thromboembolism |
| PA446294 | Torsades de Pointes |
| PA446028 | Ventricular Fibrillation |
| PA443888 | Diabetes Mellitus, Type 1 |
| PA447054 | Stroke |
| PA443842 | Death |
| PA445019 | Myocardial Infarction |
| PA445018 | Cardiomyopathies |
| PA444368 | Heart Diseases |
| PA447300 | Acquired Long QT Syndrome (aLQTS) |
| PA445131 | Obesity |
| PA443635 | Cardiovascular Diseases |
| PA444370 | Heart Failure |
| PA443797 | Coronary Disease |
| PA444818 | Lung Neoplasms |
| PA444704 | Premature Birth |
| PA446379 | Death, Sudden, Cardiac |
| PA444510 | Hyperalgesia |
| PA443450 | Asthma |
| PA443829 | Cystic Fibrosis |
| PA443632 | Cardiomyopathy, Dilated |
| PA447288 | Essential hypertension |
| PA443362 | Angina Pectoris |
| PA444552 | Hypertension |
| PA446155 | Precursor Cell Lymphoblastic Leukemia-Lymphoma |
| PA447178 | Pulmonary Disease, Chronic Obstructive |
| PA445752 | Stress |
| PA443796 | Coronary Artery Disease |
| Releated drug ID | Related drug Name |
|---|---|
| PA451258 | ritodrine |
| PA164712547 | Beta blocking agents, selective |
| PA451906 | warfarin |
| PA448681 | budesonide |
| PA449686 | fluticasone propionate |
| PA449381 | dobutamine |
| PA448547 | beclomethasone |
| PA164754818 | betamethasone |
| PA448681 | budesonide |
| PA164781399 | ciclesonide |
| PA164776996 | desonide |
| PA449247 | dexamethasone |
| PA449661 | flunisolide |
| PA449686 | fluticasone propionate |
| PA452347 | glucocorticoids |
| PA449905 | hydrocortisone |
| PA448478 | l-arginine |
| PA164747225 | l-citrulline |
| PA450466 | methylprednisolone |
| PA450541 | mometasone |
| PA450635 | nitric oxide |
| PA164777035 | paramethasone |
| PA451096 | prednisolone |
| PA451100 | prednisone |
| PA164752251 | rimexolone |
| PA451749 | triamcinolone |
| PA448976 | choline |
| PA164743471 | adenosine triphosphate |
| PA448334 | alprostadil |
| PA449470 | epinephrine |
| PA452347 | glucocorticoids |
| PA451616 | terbutaline |
| PA452604 | xenobiotics |
| PA134687887 | selective beta-2-adrenoreceptor agonists |
| PA164712535 | Beta Blocking Agents |
| PA448499 | atenolol |
| PA449456 | enalapril |
| PA134687907 | formoterol |
| PA450390 | orciprenaline |
| PA451868 | verapamil |
| PA142899133 | hexoprenaline |
| PA450550 | morphine |
| PA451300 | salmeterol |
| PA450121 | isoproterenol |
| PA448817 | carvedilol |
| PA448068 | salbutamol |
| PA165290926 | fluticasone/salmeterol |
| PA450379 | mercaptopurine |
| PA450428 | methotrexate |
| PA164713253 | Selective beta-2-adrenoreceptor agonists |
| PA451145 | propranolol |
| Drugbank ID | Action | Drug Name | Description |
|---|---|---|---|
| DB00195 | antagonist | Betaxolol | Antihypertensive Agents;Adrenergic beta-Antagonists;Sympatholytics;EENT Drugs |
| DB00264 | antagonist | Metoprolol | Antihypertensive Agents;Adrenergic Agents;Adrenergic beta-Antagonists;Sympatholytics;Antiarrhythmic Agents;Anti-Arrhythmia Agents |
| DB00368 | agonist | Norepinephrine | Vasoconstrictor Agents;Sympathomimetics;Adrenergic alpha-Agonists |
| DB00373 | antagonist | Xalacom | Antihypertensive Agents;Adrenergic beta-Antagonists;Anti-Arrhythmia Agents |
| DB00449 | agonist | Probeta - Liq Oph | Sympathomimetics;Ophthalmologicals;Adrenergic Agonists |
| DB00489 | antagonist | Sotalol | Adrenergic beta-Antagonists;Sympatholytics;Anti-Arrhythmia Agents |
| DB00521 | antagonist | Carteolol | Antihypertensive Agents;Adrenergic beta-Antagonists;Sympatholytics;Anti-Arrhythmia Agents |
| DB00571 | antagonist | Propranolol | Anti-anxiety Agents;Antihypertensive Agents;Adrenergic Agents;Adrenergic beta-Antagonists;Vasodilator Agents;Antiarrhythmic Agents;Anti-Arrhythmia Agents |
| DB00598 | antagonist | Labetalol | Antihypertensive Agents;Adrenergic beta-Antagonists;Sympatholytics;Adrenergic alpha-Antagonists |
| DB00612 | antagonist | Ziac | Antihypertensive Agents;Adrenergic Agents;Adrenergic beta-Antagonists;Sympatholytics |
| DB00668 | agonist | Zorcaine | Vasoconstrictor Agents;Sympathomimetics;Adrenergic alpha-Agonists;Mydriatics;Bronchodilator Agents;Adrenergic beta-Agonists;Adrenergic Agonists |
| DB00816 | agonist | Orciprenaline | Sympathomimetics;Bronchodilator Agents;Adrenergic beta-Agonists;Tocolytic Agents |
| DB00841 | agonist | Dobutamine | Sympathomimetics;Adrenergic beta-Agonists;Cardiotonic Agents;Sympathomimetic |
| DB00852 | partial agonist | Tussin Cough Medicine DM Antitussive Expectorant Decongestant | Vasoconstrictor Agents;Adrenergic Agents;Sympathomimetics;Central Nervous System Agents;Bronchodilator Agents;Nasal Decongestants |
| DB00866 | antagonist | Alprenolol | Antihypertensive Agents;Adrenergic beta-Antagonists;Sympatholytics;Antiarrhythmic Agents;Anti-Arrhythmia Agents |
| DB00867 | agonist | Ritodrine | Sympathomimetics;Adrenergic beta-Agonists;Tocolytic Agents;Sympathomimetic |
| DB00871 | agonist | Terbutaline | Sympathomimetics;Bronchodilator Agents;Adrenergic beta-Agonists;Tocolytic Agents;Sympathomimetic |
| DB00901 | - | Bitolterol | Bronchodilator Agents;Selective beta-2-adrenoreceptor agonists |
| DB00925 | - | Phenoxybenzamine | Antihypertensive Agents;Vasodilator Agents;Adrenergic alpha-Antagonists |
| DB00938 | agonist | Advair 500 Diskus | Bronchodilator Agents;Adrenergic beta-Agonists;Sympathomimetic |
| DB00960 | partial agonist | Viskazide 10/50tab | Antihypertensive Agents;Adrenergic beta-Antagonists;Vasodilator Agents;Serotonin Antagonists |
| DB00983 | agonist | Symbicort 200 Turbuhaler | Bronchodilator Agents;Adrenergic beta-Agonists;Sympathomimetic |
| DB01001 | agonist | Gen-Combo Sterinebs | Bronchodilator Agents;Adrenergic beta-Agonists;Tocolytic Agents |
| DB01064 | agonist | Isoproterenol | Sympathomimetics;Bronchodilator Agents;Adrenergic beta-Agonists;Cardiotonic Agents;Sympathomimetic |
| DB01102 | agonist | Arbutamine | Adrenergic beta-Agonists;Cardiotonic Agents |
| DB01136 | antagonist | Carvedilol | Antihypertensive Agents;Adrenergic Agents;Adrenergic beta-Antagonists;Vasodilator Agents;Adrenergic alpha-Antagonists |
| DB01151 | antagonist | Desipramine | Antidepressants;Adrenergic Uptake Inhibitors;Enzyme Inhibitors;Antidepressive Agents, Tricyclic;Norepinephrine-Reuptake Inhibitors |
| DB01193 | partial agonist | Acebutolol | Antihypertensive Agents;Adrenergic beta-Antagonists;Anti-Arrhythmia Agents |
| DB01203 | antagonist | Corzide Tab W Nadolol 80mg | Antihypertensive Agents;Adrenergic beta-Antagonists;Sympatholytics;Anti-Arrhythmia Agents |
| DB01210 | antagonist | Levobunolol | Adrenergic beta-Antagonists;Sympatholytics;EENT Drugs |
| DB01214 | antagonist | Metipranolol | Antihypertensive Agents;Adrenergic beta-Antagonists;Sympatholytics;Anti-Arrhythmia Agents |
| DB01274 | agonist | Arformoterol | Bronchodilator Agents;Adrenergic beta-Agonists |
| DB01288 | agonist | Duovent UDV | Sympathomimetics;Bronchodilator Agents;Adrenergic beta-Agonists;Tocolytic Agents |
| DB01291 | agonist | Pirbuterol | Bronchodilator Agents;Adrenergic beta-Agonists;Cardiotonic Agents |
| DB01295 | antagonist | Bevantolol | Antihypertensive Agents;Adrenergic beta-Antagonists;Calcium Channel Blockers |
| DB01359 | antagonist | Penbutolol | Antihypertensive Agents;Adrenergic beta-Antagonists |
| DB01363 | agonist | Tartephedreel | |
| DB01366 | agonist | Procaterol | Sympathomimetics;Bronchodilator Agents;Adrenergic beta-Agonists |
| DB01407 | agonist | Clenbuterol | Sympathomimetics;Bronchodilator Agents;Adrenergic beta-Agonists |
| DB01408 | agonist | Bambuterol | Sympathomimetics;Bronchodilator Agents;Adrenergic beta-Agonists;Tocolytic Agents |
| DB01580 | antagonist | Oxprenolol | Anti-anxiety Agents;Antihypertensive Agents;Adrenergic beta-Antagonists;Sympatholytics;Vasodilator Agents;Anti-Arrhythmia Agents |
| DB04861 | antagonist | Nebivolol | Antihypertensive Agents;Adrenergic beta-Antagonists;Vasodilator Agents |
| DB06262 | agonist | Droxidopa | Vasoconstrictor Agents;Sympathomimetics;Adrenergic alpha-Agonists |
| DB07543 | - | (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol | |
| DB08625 | - | (2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol | |
| DB08807 | partial agonist | Bopindolol | Antihypertensive Agents;Adrenergic beta-Antagonists |
| DB08808 | antagonist | Bupranolol | Antihypertensive Agents;Adrenergic beta-Antagonists;Anti-Arrhythmia Agents |
| No data |
| No data |
| No data |