Annotation Detail for CYP1B1
Basic Information Top
| Gene Symbol: | CYP1B1 ( CP1B,GLC3A,P4501B1 ) |
|---|---|
| Gene Full Name: | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| Band: | 2p22.2 |
| Quick Links | Entrez ID:1545; OMIM: 601771; Uniprot ID:CP1B1_HUMAN; ENSEMBL ID: ENSG00000138061; HGNC ID: 2597 |
| Relate to Another Database: | SFARIGene; denovo-db |
| No data |
| Desease ID | Desease Name |
|---|---|
| 1832 | Congenital abnormality |
| 1872 | Chronic simple glaucoma |
| 1901 | Endometriosis |
| 1934 | Cancer |
| 2060 | Glaucoma |
| Desease Name |
|---|
| breast and lung cancer |
| catecholestrogen formation |
| PAH-DNA adducts |
| menarche |
| colorectal cancer |
| estrogens |
| liver cancer |
| menopause |
| prostate cancer |
| glaucoma, primary open-angle ocular hypertension |
| CANCER |
| endometrial cancer |
| catecholestrogen metabolism |
| glaucoma, primary congenital |
| breast cancer |
| pregnancy loss |
| glaucoma, primary open-angle |
| METABOLIC |
| VISION |
| glaucoma |
| lung cancer |
| 1-hyrdoxypyrene glucuronide concentrations |
| sex hormones |
| REPRODUCTION |
| No data |
| Desease Name |
|---|
| Glaucoma, early-onset, digenic |
| Glaucoma 3A, primary congenital |
| Glaucoma, primary open angle, juvenile-onset |
| Peters anomaly |
| Glaucoma, primary open angle, adult-onset |
| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| C410870 | 1,2,4-trihydroxy-9,10-anthracenedione | 1,2,4-trihydroxy-9,10-anthracenedione results in decreased activity of CYP1B1 protein | decreases activity | 12379470 |
| C026486 | 1,2,5,6-dibenzanthracene | 1,2,5,6-dibenzanthracene results in increased expression of CYP1B1 mRNA | increases expression | 19358281 |
| C035342 | 1,4-naphthoquinone | CYP1B1 protein results in increased abundance of 1,4-naphthoquinone | increases abundance | 16243959 |
| C002029 | 17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol | [17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol co-treated with Paraquat co-treated with Tetrachlorodibenzodioxin] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 17275934 |
| C002029 | 17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol | 17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol results in decreased expression of CYP1B1 mRNA | decreases expression | 17275934 |
| C042881 | 1-ethynylpyrene | 1-ethynylpyrene results in decreased activity of CYP1B1 protein | decreases activity | 11922910 |
| C029350 | 1-naphthol | CYP1B1 protein results in increased abundance of 1-naphthol | increases abundance | 16243959 |
| C024336 | 1-phenylazo-2-naphthol | CYP1B1 protein results in increased oxidation of 1-phenylazo-2-naphthol | increases oxidation | 17159775 |
| C548651 | 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester | 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of CYP1B1 mRNA | increases expression | 19933214 |
| C029790 | 2,2',3',4,4',5-hexachlorobiphenyl | [2,4,4'-trichlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 15808785 |
| C541980 | 2,2',4,6'-tetramethoxystilbene | 2,2',4,6'-tetramethoxystilbene inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 19463925 |
| C541980 | 2,2',4,6'-tetramethoxystilbene | 2,2',4,6'-tetramethoxystilbene inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein] | decreases reaction|increases expression | 19463925 |
| C541980 | 2,2',4,6'-tetramethoxystilbene | 2,2',4,6'-tetramethoxystilbene results in decreased activity of CYP1B1 protein | decreases activity | 19463925 |
| C541980 | 2,2',4,6'-tetramethoxystilbene | [CYP1B1 protein co-treated with NADP] results in increased metabolism of 2,2',4,6'-tetramethoxystilbene | affects cotreatment|increases metabolic processing | 19463925 |
| C520611 | 2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester | 2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 19276279 |
| C520611 | 2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester | 2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 19276279 |
| C520611 | 2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester | 2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester results in decreased activity of CYP1B1 protein | decreases activity | 19276279 |
| C070055 | 2,3',4,4',5-pentachlorobiphenyl | [2,4,4'-trichlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 15808785 |
| C038890 | 2,3,4,7,8-pentachlorodibenzofuran | 2,3,4,7,8-pentachlorodibenzofuran results in increased expression of CYP1B1 mRNA | increases expression | 19358281 |
| C066841 | 2,3,7,8-tetrabromodibenzo-4-dioxin | 2,3,7,8-tetrabromodibenzo-4-dioxin results in increased expression of CYP1B1 mRNA | increases expression | 19167471 |
| C440850 | 2,4,3',5'-tetramethoxystilbene | 2,4,3',5'-tetramethoxystilbene inhibits the reaction [CYP1B1 protein results in increased hydroxylation of Melatonin] | decreases reaction|increases hydroxylation | 15616152 |
| C440850 | 2,4,3',5'-tetramethoxystilbene | 2,4,3',5'-tetramethoxystilbene inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 16120791 |
| C440850 | 2,4,3',5'-tetramethoxystilbene | 2,4,3',5'-tetramethoxystilbene inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein] | decreases reaction|increases expression | 16120791 |
| C440850 | 2,4,3',5'-tetramethoxystilbene | 2,4,3',5'-tetramethoxystilbene results in decreased activity of CYP1B1 protein | decreases activity | 15616152 15041469 |
| C440850 | 2,4,3',5'-tetramethoxystilbene | alpha-naphthoflavone inhibits the reaction [[CYP1B1 protein co-treated with NADP] results in increased metabolism of 2,4,3',5'-tetramethoxystilbene] | affects cotreatment|decreases reaction|increases metabolic processing | 16120791 |
| C440850 | 2,4,3',5'-tetramethoxystilbene | [CYP1B1 protein co-treated with NADP] results in increased metabolism of 2,4,3',5'-tetramethoxystilbene | affects cotreatment|increases metabolic processing | 16120791 |
| C081766 | 2,4,4'-trichlorobiphenyl | [2,4,4'-trichlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 15808785 |
| C014024 | 2,4,5,2',4',5'-hexachlorobiphenyl | [2,4,4'-trichlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 15808785 |
| C009828 | 2,4,5,2',5'-pentachlorobiphenyl | [2,4,4'-trichlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 15808785 |
| C425784 | 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole | 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole results in increased expression of CYP1B1 mRNA | increases expression | 15355884 14707267 |
| C010914 | 2,4-diaminotoluene | 2,4-diaminotoluene results in increased expression of CYP1B1 mRNA | increases expression | 20713471 |
| C013031 | 2'-hydroxychalcone | 2'-hydroxychalcone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 15596260 |
| C013031 | 2'-hydroxychalcone | 2'-hydroxychalcone results in decreased activity of CYP1B1 protein | decreases activity | 15596260 |
| C001390 | 2-hydroxyestradiol | CYP1B1 protein affects the metabolism of [2-hydroxyestradiol co-treated with Glutathione] | affects cotreatment|affects metabolic processing | 14679015 |
| C026114 | 2-xylene | 2-xylene results in decreased expression of CYP1B1 mRNA | decreases expression | 20359517 |
| C041525 | 3,3',4,5'-tetrahydroxystilbene | CYP1B1 protein affects the chemical synthesis of 3,3',4,5'-tetrahydroxystilbene | affects chemical synthesis | 15276085 |
| C520945 | 3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide | 3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP1B1 protein] | decreases reaction|increases activity | 17183067 |
| C520945 | 3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide | 3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 17183067 |
| C520945 | 3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide | 3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein] | decreases reaction|increases activity | 17183067 |
| C520945 | 3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide | 3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 17183067 |
| C520945 | 3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide | 3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide results in decreased activity of CYP1B1 protein | decreases activity | 17183067 |
| C028451 | 3,4,3',4'-tetrachlorobiphenyl | [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 15808785 |
| C027309 | 3,4,5,3',4',5'-hexachlorobiphenyl | [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 15808785 |
| C023035 | 3,4,5,3',4'-pentachlorobiphenyl | 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA | increases expression | 17686920 19615353 |
| C023035 | 3,4,5,3',4'-pentachlorobiphenyl | AHR2 protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA] | affects reaction|increases expression | 19615353 |
| C023035 | 3,4,5,3',4'-pentachlorobiphenyl | 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA | increases expression | 20471113 |
| C023035 | 3,4,5,3',4'-pentachlorobiphenyl | 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA | increases expression | 19358281 15041469 |
| C023035 | 3,4,5,3',4'-pentachlorobiphenyl | [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 15808785 |
| C023035 | 3,4,5,3',4'-pentachlorobiphenyl | 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA | increases expression | 15908097 15990133 |
| C023035 | 3,4,5,3',4'-pentachlorobiphenyl | 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 protein | increases expression | 15908097 15990133 17557910 |
| C023035 | 3,4,5,3',4'-pentachlorobiphenyl | TNF protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 protein] | increases expression|increases reaction | 17557910 |
| C509288 | 3',4'-dimethoxyflavone | 3',4'-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 16530937 19919601 |
| C509288 | 3',4'-dimethoxyflavone | 3',4'-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein] | decreases reaction|increases expression | 16530937 |
| C509288 | 3',4'-dimethoxyflavone | 3',4'-dimethoxyflavone inhibits the reaction [Plant Extracts results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 19794518 |
| C509288 | 3',4'-dimethoxyflavone | 3',4'-dimethoxyflavone results in decreased expression of CYP1B1 mRNA | decreases expression | 17637178 |
| C091547 | 3,7-dimethoxyflavone | 3,7-dimethoxyflavone results in decreased expression of CYP1B1 mRNA | decreases expression | 17637178 |
| C057714 | 3-cyano-7-ethoxycoumarin | CYP1B1 protein affects the metabolism of 3-cyano-7-ethoxycoumarin | affects metabolic processing | 20599672 |
| C038345 | 3-hydroxytamoxifen | 3-hydroxytamoxifen results in decreased activity of CYP1B1 protein | decreases activity | 12419016 |
| C091768 | 3'-methoxy-4'-nitroflavone | 3'-methoxy-4'-nitroflavone inhibits the reaction [AHR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]] | decreases reaction|increases expression|increases reaction | 15183014 |
| C091768 | 3'-methoxy-4'-nitroflavone | 3'-methoxy-4'-nitroflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein] | decreases reaction|increases expression | 15050417 |
| C047368 | 3-methylquercetin | 3-methylquercetin results in decreased expression of CYP1B1 mRNA | decreases expression | 19794518 |
| C027576 | 4-hydroxy-2-nonenal | 4-hydroxy-2-nonenal results in decreased expression of CYP1B1 mRNA | decreases expression | 12419474 |
| C451019 | 4-hydroxychalcone | 4-hydroxychalcone results in decreased activity of CYP1B1 protein | decreases activity | 15596260 |
| C014036 | 4-hydroxyestradiol-17 beta | CYP1B1 gene polymorphism results in increased chemical synthesis of 4-hydroxyestradiol-17 beta | increases chemical synthesis | 18187806 |
| C014036 | 4-hydroxyestradiol-17 beta | CYP1B1 protein affects the chemical synthesis of 4-hydroxyestradiol-17 beta | affects chemical synthesis | 15142886 |
| C014036 | 4-hydroxyestradiol-17 beta | CYP1B1 protein affects the metabolism of [4-hydroxyestradiol-17 beta co-treated with Glutathione] | affects cotreatment|affects metabolic processing | 14679015 |
| C014036 | 4-hydroxyestradiol-17 beta | resveratrol inhibits the reaction [CYP1B1 protein affects the chemical synthesis of 4-hydroxyestradiol-17 beta] | affects chemical synthesis|decreases reaction | 15142886 |
| C014036 | 4-hydroxyestradiol-17 beta | CYP1B1 protein affects the chemical synthesis of 4-hydroxyestradiol-17 beta | affects chemical synthesis | 15901486 |
| C014036 | 4-hydroxyestradiol-17 beta | CYP1B1 protein results in increased chemical synthesis of 4-hydroxyestradiol-17 beta | increases chemical synthesis | 18456490 18497090 |
| C016601 | 4-hydroxytamoxifen | 4-hydroxytamoxifen inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ESR1 protein binds to CYP1B1 promoter]] | affects binding|decreases reaction|increases reaction | 19460354 |
| C016601 | 4-hydroxytamoxifen | 4-hydroxytamoxifen results in decreased activity of CYP1B1 protein | decreases activity | 12419016 |
| C016601 | 4-hydroxytamoxifen | 4-hydroxytamoxifen results in increased expression of CYP1B1 mRNA | increases expression | 19901195 |
| C016583 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | CYP1B1 protein affects the metabolism of and results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | affects metabolic processing|increases activity | 11774366 |
| C016583 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | Grape Seed Proanthocyanidins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 20146248 |
| C103112 | 5,7,4'-trimethylapigenin | 5,7,4'-trimethylapigenin results in decreased expression of CYP1B1 mRNA | decreases expression | 17637178 |
| C060298 | 5,7-dimethoxyflavone | 5,7-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 16530937 |
| C060298 | 5,7-dimethoxyflavone | 5,7-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein] | decreases reaction|increases expression | 16530937 |
| C060298 | 5,7-dimethoxyflavone | 5,7-dimethoxyflavone results in decreased activity of CYP1B1 protein | decreases activity | 15905203 |
| C111855 | 6-formylindolo(3,2-b)carbazole | 6-formylindolo(3,2-b)carbazole results in increased expression of CYP1B1 mRNA | increases expression | 19615353 |
| C111855 | 6-formylindolo(3,2-b)carbazole | AHR2 protein affects the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of CYP1B1 mRNA] | affects reaction|increases expression | 19615353 |
| C054923 | 6-methyl-1,3,8-trichlorodibenzofuran | 6-methyl-1,3,8-trichlorodibenzofuran results in increased expression of CYP1B1 mRNA | increases expression | 19828881 |
| C419147 | 7-benzyloxy-4-trifluoromethylcoumarin | CYP1B1 protein affects the metabolism of 7-benzyloxy-4-trifluoromethylcoumarin | affects metabolic processing | 20599672 |
| C076580 | 7-methoxyresorufin | CYP1B1 protein affects the metabolism of 7-methoxyresorufin | affects metabolic processing | 20599672 |
| C421010 | 9-(4'-aminophenyl)-9H-pyrido(3,4-b)indole | CYP1B1 protein results in increased chemical synthesis of 9-(4'-aminophenyl)-9H-pyrido(3,4-b)indole | increases chemical synthesis | 15279827 |
| D000242 | Cyclic AMP | Cyclic AMP results in increased expression of CYP1B1 mRNA | increases expression | 12859982 |
| D000242 | Cyclic AMP | Cyclic AMP results in increased expression of CYP1B1 protein | increases expression | 12859982 |
| D000242 | Cyclic AMP | AHR protein promotes the reaction [Cyclic AMP results in increased expression of CYP1B1 mRNA] | increases expression|increases reaction | 12859982 |
| D000242 | Cyclic AMP | Cyclic AMP promotes the reaction [AHR protein binds to CYP1B1 enhancer] | affects binding|increases reaction | 12859982 |
| D000242 | Cyclic AMP | Cyclic AMP promotes the reaction [CREB1 protein binds to CYP1B1 enhancer] | affects binding|increases reaction | 12859982 |
| D000242 | Cyclic AMP | Cyclic AMP results in increased expression of CYP1B1 mRNA | increases expression | 12859982 |
| D016604 | Aflatoxin B1 | Aflatoxin B1 affects the expression of CYP1B1 protein | affects expression | 20106945 |
| C010078 | alizarin | alizarin results in decreased activity of CYP1B1 protein | decreases activity | 12379470 |
| C038491 | allyl sulfide | allyl sulfide results in increased expression of CYP1B1 mRNA | increases expression | 17129689 |
| C038491 | allyl sulfide | [Diethylstilbestrol co-treated with allyl sulfide] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 17129689 |
| C011512 | alpha-naphthoflavone | alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 19403181 |
| C011512 | alpha-naphthoflavone | alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 19403181 |
| C011512 | alpha-naphthoflavone | alpha-naphthoflavone results in decreased expression of CYP1B1 mRNA | decreases expression | 19403181 |
| C011512 | alpha-naphthoflavone | alpha-naphthoflavone results in increased expression of CYP1B1 mRNA | increases expression | 19403181 |
| C011512 | alpha-naphthoflavone | alpha-naphthoflavone inhibits the reaction [[CYP1B1 protein co-treated with NADP] results in increased metabolism of 2,4,3',5'-tetramethoxystilbene] | affects cotreatment|decreases reaction|increases metabolic processing | 16120791 |
| C011512 | alpha-naphthoflavone | alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 15075337 19182260 |
| C011512 | alpha-naphthoflavone | alpha-naphthoflavone results in decreased activity of CYP1B1 protein | decreases activity | 15280921 |
| C011512 | alpha-naphthoflavone | CYP1B1 protein results in increased metabolism of alpha-naphthoflavone | increases metabolic processing | 16120791 |
| C011512 | alpha-naphthoflavone | alpha-naphthoflavone inhibits the reaction [AHR protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]] | decreases reaction|increases expression|increases reaction | 11577022 |
| C011164 | amentoflavone | amentoflavone results in decreased activity of CYP1B1 protein | decreases activity | 16271822 |
| D000588 | Amines | CYP1B1 protein affects the metabolism of Amines | affects metabolic processing | 15122594 |
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of CYP1B1 mRNA | affects expression | 16483693 |
| C030419 | andrographolide | [andrographolide co-treated with benz(a)anthracene] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 17825862 |
| C023650 | aniline | CYP1B1 protein affects the metabolism of [norharman co-treated with aniline] | affects cotreatment|affects metabolic processing | 15279827 |
| D047310 | Apigenin | Apigenin results in decreased activity of CYP1B1 protein | decreases activity | 16271822 |
| D016718 | Arachidonic Acid | CYP1B1 protein affects the metabolism of Arachidonic Acid | affects metabolic processing | 15258110 |
| D016718 | Arachidonic Acid | CYP1B1 protein affects the metabolism of Arachidonic Acid | affects metabolic processing | 15258110 |
| C006632 | arsenic trioxide | arsenic trioxide affects the expression of CYP1B1 mRNA | affects expression | 17530438 |
| C015001 | arsenite | [arsenite co-treated with Benzo(a)pyrene] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 15894712 |
| C015001 | arsenite | arsenite results in decreased expression of CYP1B1 mRNA | decreases expression | 15894712 |
| D001374 | Azacitidine | Azacitidine promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | increases expression|increases reaction | 12927368 |
| D001374 | Azacitidine | Azacitidine results in increased expression of CYP1B1 mRNA | increases expression | 12927368 |
| C006680 | baicalein | baicalein inhibits the reaction [benz(a)anthracene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 12224597 |
| C030935 | benz(a)anthracene | baicalein inhibits the reaction [benz(a)anthracene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 12224597 |
| C030935 | benz(a)anthracene | benz(a)anthracene results in increased expression of CYP1B1 mRNA | increases expression | 19358281 12224597 |
| C030935 | benz(a)anthracene | [andrographolide co-treated with benz(a)anthracene] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 17825862 |
| C030935 | benz(a)anthracene | benz(a)anthracene results in increased expression of CYP1B1 mRNA | increases expression | 17825862 |
| D001554 | Benzene | Benzene results in decreased expression of CYP1B1 mRNA | decreases expression | 20359517 |
| C017228 | benzo(a)pyrene 7,8-dihydrodiol | benzo(a)pyrene 7,8-dihydrodiol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 21028851 |
| C017228 | benzo(a)pyrene 7,8-dihydrodiol | benzo(a)pyrene 7,8-dihydrodiol results in increased expression of CYP1B1 mRNA | increases expression | 21028851 |
| C017228 | benzo(a)pyrene 7,8-dihydrodiol | bergamottin inhibits the reaction [CYP1B1 protein results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol] | decreases reaction|increases oxidation | 15861043 |
| C017228 | benzo(a)pyrene 7,8-dihydrodiol | CYP1B1 protein affects the metabolism of and results in increased activity of benzo(a)pyrene 7,8-dihydrodiol | affects metabolic processing|increases activity | 15720144 |
| C017228 | benzo(a)pyrene 7,8-dihydrodiol | CYP1B1 protein results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol | increases oxidation | 15861043 |
| C017228 | benzo(a)pyrene 7,8-dihydrodiol | imperatorin inhibits the reaction [CYP1B1 protein results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol] | decreases reaction|increases oxidation | 15861043 |
| C017228 | benzo(a)pyrene 7,8-dihydrodiol | isoimperatorin inhibits the reaction [CYP1B1 protein results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol] | decreases reaction|increases oxidation | 15861043 |
| C017228 | benzo(a)pyrene 7,8-dihydrodiol | isopimpinellin inhibits the reaction [CYP1B1 protein results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol] | decreases reaction|increases oxidation | 15861043 |
| C017228 | benzo(a)pyrene 7,8-dihydrodiol | NADP promotes the reaction [CYP1B1 protein affects the metabolism of and results in increased activity of benzo(a)pyrene 7,8-dihydrodiol] | affects metabolic processing|increases activity|increases reaction | 15720144 |
| C076588 | benzo(a)pyrene-7,8-dione | benzo(a)pyrene-7,8-dione results in increased expression of and results in increased activity of CYP1B1 protein | increases activity|increases expression | 16411658 |
| C076588 | benzo(a)pyrene-7,8-dione | benzo(a)pyrene-7,8-dione results in increased expression of CYP1B1 mRNA | increases expression | 16411658 |
| C006703 | benzo(b)fluoranthene | [phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a,l)pyrene co-treated with benzo(b)fluoranthene] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 15566942 |
| D019324 | beta-Naphthoflavone | beta-Naphthoflavone results in increased expression of CYP1B1 mRNA | increases expression | 16985168 14990334 12623754 |
| D019324 | beta-Naphthoflavone | beta-Naphthoflavone results in increased expression of CYP1B1 mRNA | increases expression | 19389873 19969063 |
| D019324 | beta-Naphthoflavone | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 20045035 18164116 |
| C022921 | benzo(k)fluoranthene | benzo(k)fluoranthene results in increased expression of CYP1B1 mRNA | increases expression | 20471113 |
| C022921 | benzo(k)fluoranthene | benzo(k)fluoranthene results in increased expression of CYP1B1 mRNA | increases expression | 19358281 15566942 |
| C022921 | benzo(k)fluoranthene | [phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a,l)pyrene co-treated with benzo(b)fluoranthene] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 15566942 |
| D001564 | Benzo(a)pyrene | alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 19403181 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of CYP1B1 mRNA | increases expression | 19403181 |
| D001564 | Benzo(a)pyrene | CYP1B1 protein affects the metabolism of Benzo(a)pyrene | affects metabolic processing | 20599672 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of CYP1B1 mRNA | increases expression | 20471113 |
| D001564 | Benzo(a)pyrene | 3',4'-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 16530937 19919601 |
| D001564 | Benzo(a)pyrene | 3',4'-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein] | decreases reaction|increases expression | 16530937 |
| D001564 | Benzo(a)pyrene | 5,7-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 16530937 |
| D001564 | Benzo(a)pyrene | 5,7-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein] | decreases reaction|increases expression | 16530937 |
| D001564 | Benzo(a)pyrene | AR protein promotes the reaction [Benzo(a)pyrene results in decreased expression of CYP1B1 mRNA] | decreases expression|increases reaction | 15041469 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene affects the expression of CYP1B1 mRNA | affects expression | 20624995 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene promotes the reaction [Estradiol results in increased expression of CYP1B1 mRNA] | increases expression|increases reaction | 19619570 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased activity of CYP1B1 protein | increases activity | 15905203 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of CYP1B1 mRNA | increases expression | 20228066 16258175 15713371 18061397 15735009 18214805 19576839 19358281 20553787 16381670 20951464 15905203 15566942 15297370 19244278 15808406 19919601 20163913 20106945 15808407 15041469 19879933 19879285 19152381 19835593 16530937 20064835 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of CYP1B1 protein | increases expression | 15297370 19576839 16530937 15735009 15905203 |
| D001564 | Benzo(a)pyrene | Calcium promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | increases expression|increases reaction | 16237193 |
| D001564 | Benzo(a)pyrene | chlorophyllin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 19152381 20163913 |
| D001564 | Benzo(a)pyrene | chrysoeriol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 20553787 |
| D001564 | Benzo(a)pyrene | cobaltous chloride inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 20228066 |
| D001564 | Benzo(a)pyrene | CYP1B1 protein affects the metabolism of and results in increased activity of Benzo(a)pyrene | affects metabolic processing|increases activity | 15958554 |
| D001564 | Benzo(a)pyrene | CYP1B1 protein polymorphism affects the metabolism of and results in increased activity of Benzo(a)pyrene | affects metabolic processing|increases activity | 15958554 |
| D001564 | Benzo(a)pyrene | CYP1B1 protein polymorphism results in decreased metabolism of Benzo(a)pyrene | decreases metabolic processing | 15958554 |
| D001564 | Benzo(a)pyrene | CYP1B1 protein results in increased hydrolysis of Benzo(a)pyrene | increases hydrolysis | 19919601 |
| D001564 | Benzo(a)pyrene | CYP1B1 protein results in increased metabolism of Benzo(a)pyrene | increases metabolic processing | 19879933 |
| D001564 | Benzo(a)pyrene | [Dust co-treated with Benzo(a)pyrene] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 15735009 |
| D001564 | Benzo(a)pyrene | [Dust co-treated with Benzo(a)pyrene] results in increased expression of CYP1B1 protein | affects cotreatment|increases expression | 15735009 |
| D001564 | Benzo(a)pyrene | Grape Seed Proanthocyanidins inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 20146248 |
| D001564 | Benzo(a)pyrene | Particulate Matter inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 19835593 |
| D001564 | Benzo(a)pyrene | [phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a,l)pyrene co-treated with benzo(b)fluoranthene] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 15566942 |
| D001564 | Benzo(a)pyrene | resveratrol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 15162144 11279601 |
| D001564 | Benzo(a)pyrene | trichostatin A inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 15713371 |
| D001564 | Benzo(a)pyrene | vorinostat inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 15713371 |
| D001564 | Benzo(a)pyrene | AHR protein affects the reaction [Benzo(a)pyrene results in increased activity of CYP1B1 protein] | affects reaction|increases activity | 11577022 |
| D001564 | Benzo(a)pyrene | AHR protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein] | increases expression|increases reaction | 11577022 |
| D001564 | Benzo(a)pyrene | alpha-naphthoflavone inhibits the reaction [AHR protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]] | decreases reaction|increases expression|increases reaction | 11577022 |
| D001564 | Benzo(a)pyrene | [arsenite co-treated with Benzo(a)pyrene] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 15894712 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene affects the expression of CYP1B1 mRNA | affects expression | 15037607 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1B1 protein | increases activity|increases expression | 11577022 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of CYP1B1 mRNA | increases expression | 20127859 17997381 20713471 11577022 19406224 19666105 20371670 15894712 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of CYP1B1 protein | increases expression | 17997381 19666105 |
| D001564 | Benzo(a)pyrene | Dactinomycin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 11577022 |
| D001564 | Benzo(a)pyrene | ellipticine inhibits the reaction [AHR protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]] | decreases reaction|increases expression|increases reaction | 11577022 |
| D001564 | Benzo(a)pyrene | [SOD1 protein co-treated with CAT protein] promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | affects cotreatment|increases expression|increases reaction | 19666105 |
| D001564 | Benzo(a)pyrene | [SOD1 protein co-treated with CAT protein] promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein] | affects cotreatment|increases expression|increases reaction | 19666105 |
| D001564 | Benzo(a)pyrene | SOD1 protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | increases expression|increases reaction | 19666105 |
| D001564 | Benzo(a)pyrene | SOD1 protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein] | increases expression|increases reaction | 19666105 |
| D001564 | Benzo(a)pyrene | AHR protein affects the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | affects reaction|increases expression | 19497421 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased activity of CYP1B1 protein | increases activity | 19497421 15315710 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of CYP1B1 mRNA | increases expression | 19889059 16198082 20412032 15315710 19497421 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of CYP1B1 protein | increases expression | 16198082 16237193 20412032 19889059 |
| D001564 | Benzo(a)pyrene | chrysene inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 15315710 |
| D001564 | Benzo(a)pyrene | Tetrachlorodibenzodioxin promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein] | increases expression|increases reaction | 16198082 |
| D015123 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of CYP1B1 mRNA | decreases expression | 20018196 |
| D015123 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of CYP1B1 mRNA | increases expression | 20382639 17944540 19150397 |
| D015123 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | CYP1B1 protein affects the chemical synthesis of 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | affects chemical synthesis | 15958554 15720144 |
| D015123 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | CYP1B1 protein polymorphism affects the chemical synthesis of 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | affects chemical synthesis | 15958554 |
| D015123 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | CYP1B1 protein polymorphism results in decreased chemical synthesis of 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | decreases chemical synthesis | 15958554 |
| D015123 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | NADP promotes the reaction [CYP1B1 protein affects the chemical synthesis of 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide] | affects chemical synthesis|increases reaction | 15720144 |
| C072553 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde | benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased stability of CYP1B1 protein | increases stability | 15486049 |
| C057754 | benzyloxyresorufin | CYP1B1 protein affects the metabolism of benzyloxyresorufin | affects metabolic processing | 20599672 |
| C068337 | bergamottin | bergamottin inhibits the reaction [CYP1B1 protein results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol] | decreases reaction|increases oxidation | 15861043 |
| C068337 | bergamottin | bergamottin results in decreased activity of CYP1B1 protein | decreases activity | 15861043 |
| C068337 | bergamottin | bergamottin results in decreased activity of CYP1B1 protein polymorphism | decreases activity | 15861043 |
| C095105 | bexarotene | bexarotene results in increased expression of CYP1B1 mRNA | increases expression | 16648578 |
| C004541 | biochanin A | CYP1B1 protein results in decreased methylation of biochanin A | decreases methylation | 15479032 |
| D001710 | Biotin | Biotin results in increased expression of and results in increased activity of CYP1B1 protein | increases activity|increases expression | 15333708 |
| D001710 | Biotin | Biotin results in increased expression of CYP1B1 mRNA | increases expression | 15333708 15219929 |
| C006780 | bisphenol A | bisphenol A affects the expression of CYP1B1 mRNA | affects expression | 20170705 |
| C006780 | bisphenol A | bisphenol A results in decreased expression of CYP1B1 mRNA | decreases expression | 16474171 |
| C006780 | bisphenol A | bisphenol A results in increased expression of CYP1B1 mRNA | increases expression | 16474171 |
| C006780 | bisphenol A | bisphenol A results in decreased expression of CYP1B1 mRNA | decreases expression | 12075121 |
| D020122 | tert-Butylhydroperoxide | tert-Butylhydroperoxide results in increased expression of CYP1B1 mRNA | increases expression | 12414654 |
| D019256 | Cadmium Chloride | Cadmium Chloride results in decreased expression of CYP1B1 mRNA | decreases expression | 12760830 |
| D002118 | Calcium | Calcium promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | increases expression|increases reaction | 16237193 |
| D002118 | Calcium | Calcium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | increases expression|increases reaction | 16237193 |
| C059041 | calyculin A | calyculin A promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | increases expression|increases reaction | 10696073 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in increased expression of CYP1B1 mRNA | increases expression | 17484886 |
| C023386 | chlorinated dibenzofurans | [polychlorodibenzo-4-dioxin co-treated with chlorinated dibenzofurans] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 17850846 |
| C023386 | chlorinated dibenzofurans | [Polychlorinated Biphenyls co-treated with polychlorodibenzo-4-dioxin co-treated with chlorinated dibenzofurans] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 15858227 |
| D020111 | Chlorodiphenyl (54% Chlorine) | Chlorodiphenyl (54% Chlorine) results in increased expression of CYP1B1 mRNA | increases expression | 17851650 |
| D020111 | Chlorodiphenyl (54% Chlorine) | Chlorodiphenyl (54% Chlorine) results in increased expression of CYP1B1 mRNA | increases expression | 11323195 18178546 |
| C007020 | chlorophyllin | chlorophyllin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 20163913 19152381 |
| C007020 | chlorophyllin | chlorophyllin results in increased expression of CYP1B1 mRNA | increases expression | 19152381 |
| C031180 | chrysene | chrysene results in increased expression of CYP1B1 mRNA | increases expression | 15566942 |
| C031180 | chrysene | chrysene inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 15315710 |
| C007054 | chrysoeriol | chrysoeriol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 20553787 |
| D003033 | Coal Tar | Coal Tar results in increased expression of CYP1B1 mRNA | increases expression | 16882163 |
| D003033 | Coal Tar | Coal Tar results in increased expression of CYP1B1 protein | increases expression | 15720126 |
| C018021 | cobaltous chloride | cobaltous chloride inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 20228066 |
| D009249 | NADP | alpha-naphthoflavone inhibits the reaction [[CYP1B1 protein co-treated with NADP] results in increased metabolism of 2,4,3',5'-tetramethoxystilbene] | affects cotreatment|decreases reaction|increases metabolic processing | 16120791 |
| D009249 | NADP | [CYP1B1 protein co-treated with NADP] results in increased metabolism of 2,2',4,6'-tetramethoxystilbene | affects cotreatment|increases metabolic processing | 19463925 |
| D009249 | NADP | [CYP1B1 protein co-treated with NADP] results in increased metabolism of 2,4,3',5'-tetramethoxystilbene | affects cotreatment|increases metabolic processing | 16120791 |
| D009249 | NADP | NADP promotes the reaction [CYP1B1 protein affects the chemical synthesis of 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide] | affects chemical synthesis|increases reaction | 15720144 |
| D009249 | NADP | NADP promotes the reaction [CYP1B1 protein affects the metabolism of and results in increased activity of benzo(a)pyrene 7,8-dihydrodiol] | affects metabolic processing|increases activity|increases reaction | 15720144 |
| D003474 | Curcumin | Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 19018768 |
| D003474 | Curcumin | Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein] | decreases reaction|increases expression | 19018768 |
| D003474 | Curcumin | Curcumin results in decreased expression of CYP1B1 mRNA | decreases expression | 17637178 |
| D003513 | Cycloheximide | Cycloheximide results in increased expression of CYP1B1 mRNA | increases expression | 19684285 |
| D003513 | Cycloheximide | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 19684285 |
| D003520 | Cyclophosphamide | Cyclophosphamide results in decreased expression of CYP1B1 mRNA | decreases expression | 12167460 |
| D016572 | Cyclosporine | Cyclosporine results in increased expression of CYP1B1 mRNA | increases expression | 20106945 |
| D015084 | 2,4-Dichlorophenoxyacetic Acid | 2,4-Dichlorophenoxyacetic Acid results in increased expression of CYP1B1 mRNA | increases expression | 10910964 |
| D003609 | Dactinomycin | Dactinomycin inhibits the reaction [NSC 674495 results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 11752201 |
| D003609 | Dactinomycin | Dactinomycin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 11577022 |
| D003609 | Dactinomycin | Dactinomycin results in decreased expression of CYP1B1 mRNA | decreases expression | 11577022 |
| C004742 | daidzein | CYP1B1 protein affects the chemical synthesis of daidzein | affects chemical synthesis | 15479032 |
| C004742 | daidzein | daidzein results in decreased activity of CYP1B1 protein | decreases activity | 15479032 |
| D003634 | DDT | [indole-3-carbinol co-treated with DDT] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 17311112 |
| C014347 | decitabine | decitabine affects the expression of CYP1B1 mRNA | affects expression | 17145863 |
| C014347 | decitabine | decitabine affects the methylation of CYP1B1 gene | affects methylation | 17630775 |
| D003907 | Dexamethasone | [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 15967407 |
| D003907 | Dexamethasone | [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CYP1B1 protein | affects cotreatment|increases expression | 15967407 |
| D003907 | Dexamethasone | Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | increases expression|increases reaction | 17690134 |
| D003907 | Dexamethasone | Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]] | decreases reaction|increases expression|increases reaction | 17690134 |
| C041517 | dibenzo(a,l)pyrene | dibenzo(a,l)pyrene results in increased expression of CYP1B1 mRNA | increases expression | 15566942 |
| C041517 | dibenzo(a,l)pyrene | [phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a,l)pyrene co-treated with benzo(b)fluoranthene] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 15566942 |
| C041517 | dibenzo(a,l)pyrene | CYP1B1 protein results in increased activity of dibenzo(a,l)pyrene | increases activity | 15606143 |
| D003993 | Dibutyl Phthalate | Dibutyl Phthalate results in increased expression of and results in increased activity of CYP1B1 protein | increases activity|increases expression | 16040568 |
| D003993 | Dibutyl Phthalate | Dibutyl Phthalate results in increased expression of CYP1B1 mRNA | increases expression | 16040568 |
| D003994 | Bucladesine | Bucladesine results in increased expression of CYP1B1 mRNA | increases expression | 11559018 |
| D003633 | Dichlorodiphenyl Dichloroethylene | Dichlorodiphenyl Dichloroethylene results in increased expression of CYP1B1 mRNA | increases expression | 16040568 |
| D004026 | Dieldrin | Dieldrin results in increased expression of CYP1B1 mRNA | increases expression | 10910964 |
| D004040 | Dietary Carbohydrates | Dietary Carbohydrates results in increased expression of CYP1B1 mRNA | increases expression | 17490981 |
| D004041 | Dietary Fats | [9,10-Dimethyl-1,2-benzanthracene co-treated with Dietary Fats] results in decreased expression of CYP1B1 mRNA | affects cotreatment|decreases expression | 19750107 |
| D004041 | Dietary Fats | Dietary Fats results in decreased expression of CYP1B1 mRNA | decreases expression | 18042831 |
| D004041 | Dietary Fats | [Tetrachlorodibenzodioxin co-treated with Dietary Fats] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 20435547 |
| D004051 | Diethylhexyl Phthalate | Diethylhexyl Phthalate results in increased expression of and results in increased activity of CYP1B1 protein | increases activity|increases expression | 16040568 |
| D004051 | Diethylhexyl Phthalate | Diethylhexyl Phthalate results in increased expression of CYP1B1 mRNA | increases expression | 16040568 |
| D004052 | Diethylnitrosamine | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 20045035 18164116 |
| C007379 | diethyl phthalate | diethyl phthalate results in increased expression of and results in increased activity of CYP1B1 protein | increases activity|increases expression | 16040568 |
| C007379 | diethyl phthalate | diethyl phthalate results in increased expression of CYP1B1 mRNA | increases expression | 16040568 |
| D004054 | Diethylstilbestrol | [Diethylstilbestrol co-treated with allyl sulfide] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 17129689 |
| D004054 | Diethylstilbestrol | Diethylstilbestrol results in increased expression of CYP1B1 mRNA | increases expression | 17129689 |
| C444299 | diindolylmethane | diindolylmethane analog results in increased expression of CYP1B1 mRNA | increases expression | 11294972 |
| C444299 | diindolylmethane | diindolylmethane results in increased expression of CYP1B1 mRNA | increases expression | 11294972 |
| D015127 | 9,10-Dimethyl-1,2-benzanthracene | 2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 19276279 |
| D015127 | 9,10-Dimethyl-1,2-benzanthracene | 2'-hydroxychalcone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 15596260 |
| D015127 | 9,10-Dimethyl-1,2-benzanthracene | 3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP1B1 protein] | decreases reaction|increases activity | 17183067 |
| D015127 | 9,10-Dimethyl-1,2-benzanthracene | 3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 17183067 |
| D015127 | 9,10-Dimethyl-1,2-benzanthracene | 9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP1B1 protein | increases activity | 17183067 |
| D015127 | 9,10-Dimethyl-1,2-benzanthracene | 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA | increases expression | 19276279 17183067 15596260 12097275 |
| D015127 | 9,10-Dimethyl-1,2-benzanthracene | fluasterone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 12097275 |
| D015127 | 9,10-Dimethyl-1,2-benzanthracene | S-sulindac inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 19276279 |
| D015127 | 9,10-Dimethyl-1,2-benzanthracene | [9,10-Dimethyl-1,2-benzanthracene co-treated with Dietary Fats] results in decreased expression of CYP1B1 mRNA | affects cotreatment|decreases expression | 19750107 |
| D015127 | 9,10-Dimethyl-1,2-benzanthracene | 9,10-Dimethyl-1,2-benzanthracene results in increased expression of and results in increased activity of CYP1B1 protein | increases activity|increases expression | 15667830 |
| D015127 | 9,10-Dimethyl-1,2-benzanthracene | 9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA | increases expression | 11559018 |
| D015127 | 9,10-Dimethyl-1,2-benzanthracene | CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene | affects response to substance | 15331171 |
| D015127 | 9,10-Dimethyl-1,2-benzanthracene | CYP1B1 protein results in increased activity of 9,10-Dimethyl-1,2-benzanthracene | increases activity | 15606143 |
| D015127 | 9,10-Dimethyl-1,2-benzanthracene | CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene | increases metabolic processing | 11376689 |
| D015127 | 9,10-Dimethyl-1,2-benzanthracene | CYP1B1 protein results in increased susceptibility to 9,10-Dimethyl-1,2-benzanthracene | increases response to substance | 15843505 11323178 15580705 |
| D004121 | Dimethyl Sulfoxide | Dimethyl Sulfoxide affects the expression of CYP1B1 mRNA | affects expression | 12843640 |
| C067311 | docetaxel | CYP1B1 gene polymorphism affects the susceptibility to docetaxel | affects response to substance | 18187806 |
| D004365 | Drugs, Chinese Herbal | Drugs, Chinese Herbal promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | increases expression|increases reaction | 16901605 |
| D004365 | Drugs, Chinese Herbal | Drugs, Chinese Herbal results in increased expression of CYP1B1 mRNA | increases expression | 16901605 |
| D004391 | Dust | [Dust co-treated with Benzo(a)pyrene] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 15735009 |
| D004391 | Dust | [Dust co-treated with Benzo(a)pyrene] results in increased expression of CYP1B1 protein | affects cotreatment|increases expression | 15735009 |
| D004391 | Dust | Dust results in increased expression of CYP1B1 mRNA | increases expression | 17805423 15735009 |
| D004391 | Dust | Dust results in increased expression of CYP1B1 protein | increases expression | 15735009 |
| C034192 | ellipticine | ellipticine inhibits the reaction [AHR protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]] | decreases reaction|increases expression|increases reaction | 11577022 |
| D004642 | Emodin | Emodin results in increased expression of CYP1B1 mRNA | increases expression | 14990334 |
| C091891 | epsilon-viniferin | epsilon-viniferin results in decreased activity of CYP1B1 protein | decreases activity | 12818727 |
| D004958 | Estradiol | Benzo(a)pyrene promotes the reaction [Estradiol results in increased expression of CYP1B1 mRNA] | increases expression|increases reaction | 19619570 |
| D004958 | Estradiol | CYP1B1 protein affects the metabolism of Estradiol | affects metabolic processing | 15507517 15142886 |
| D004958 | Estradiol | CYP1B1 protein polymorphism results in increased hydroxylation of Estradiol | increases hydroxylation | 15285606 |
| D004958 | Estradiol | CYP1B1 protein results in increased hydroxylation of Estradiol | increases hydroxylation | 15763594 15961252 11074351 |
| D004958 | Estradiol | CYP1B1 protein results in increased oxidation of Estradiol | increases oxidation | 15377160 |
| D004958 | Estradiol | [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 19619570 |
| D004958 | Estradiol | Estradiol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 15837795 |
| D004958 | Estradiol | Estradiol promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein] | increases activity|increases reaction | 15157572 |
| D004958 | Estradiol | Estradiol promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | increases expression|increases reaction | 19619570 |
| D004958 | Estradiol | Estradiol promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein] | increases expression|increases reaction | 19619570 |
| D004958 | Estradiol | Estradiol results in decreased expression of CYP1B1 mRNA | decreases expression | 16474171 |
| D004958 | Estradiol | Estradiol results in increased activity of CYP1B1 protein | increases activity | 15157572 |
| D004958 | Estradiol | Estradiol results in increased expression of CYP1B1 mRNA | increases expression | 16474171 19619570 20106945 |
| D004958 | Estradiol | resveratrol inhibits the reaction [CYP1B1 protein affects the metabolism of Estradiol] | affects metabolic processing|decreases reaction | 15142886 |
| D004958 | Estradiol | Estradiol results in increased expression of CYP1B1 mRNA | increases expression | 16280380 |
| D004958 | Estradiol | fulvestrant inhibits the reaction [Estradiol results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 16280380 |
| D004958 | Estradiol | CYP1B1 protein results in increased hydroxylation of Estradiol | increases hydroxylation | 10910964 15908097 |
| D004958 | Estradiol | CYP1B1 protein results in increased metabolism of Estradiol | increases metabolic processing | 18456490 |
| D004967 | Estrogens | CYP1B1 gene polymorphism affects the metabolism of Estrogens | affects metabolic processing | 16850246 15777990 |
| D004967 | Estrogens | CYP1B1 gene polymorphism affects the susceptibility to [Estrogens co-treated with Medroxyprogesterone Acetate] | affects cotreatment|affects response to substance | 15987428 |
| D004967 | Estrogens | CYP1B1 protein affects the metabolism of Estrogens | affects metabolic processing | 15987428 |
| D004967 | Estrogens | CYP1B1 protein results in increased hydroxylation of Estrogens | increases hydroxylation | 15734958 |
| D004967 | Estrogens | CYP1B1 protein results in increased hydroxylation of Estrogens | increases hydroxylation | 15342454 |
| D004970 | Estrone | CYP1B1 protein results in increased hydroxylation of Estrone | increases hydroxylation | 15763594 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in decreased expression of CYP1B1 mRNA | decreases expression | 12075121 |
| C004912 | ethylbenzene | ethylbenzene results in decreased expression of CYP1B1 mRNA | decreases expression | 20359517 |
| C039614 | ethylisopropylamiloride | ethylisopropylamiloride results in decreased activity of CYP1B1 protein | decreases activity | 15081870 |
| D015025 | Zearalenone | Zearalenone promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein] | increases activity|increases reaction | 15157572 |
| D015025 | Zearalenone | Zearalenone results in increased activity of CYP1B1 protein | increases activity | 15157572 |
| C043562 | flavone | flavone results in increased expression of CYP1B1 mRNA | increases expression | 15890477 |
| C106219 | fluasterone | fluasterone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 12097275 |
| C106219 | fluasterone | fluasterone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 12097275 |
| D015073 | 2-Acetylaminofluorene | 2-Acetylaminofluorene results in increased expression of CYP1B1 mRNA | increases expression | 17317680 20713471 |
| D015073 | 2-Acetylaminofluorene | TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of CYP1B1 mRNA] | affects reaction|increases expression | 17317680 |
| D019793 | Fluorescein | CYP1B1 protein affects the metabolism of Fluorescein analog | affects metabolic processing | 20599672 |
| C007768 | formononetin | CYP1B1 protein results in decreased methylation of formononetin | decreases methylation | 15479032 |
| C070081 | fulvestrant | fulvestrant inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ESR1 protein binds to CYP1B1 promoter]] | affects binding|decreases reaction|increases reaction | 19460354 |
| C070081 | fulvestrant | fulvestrant inhibits the reaction [Estradiol results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 16280380 |
| D019833 | Genistein | CYP1B1 protein affects the chemical synthesis of Genistein | affects chemical synthesis | 15479032 |
| D019833 | Genistein | Genistein results in decreased activity of CYP1B1 protein | decreases activity | 15479032 |
| D019833 | Genistein | Genistein results in decreased expression of CYP1B1 mRNA | decreases expression | 16474171 15257099 |
| D019833 | Genistein | Genistein results in increased expression of CYP1B1 mRNA | increases expression | 16474171 |
| D019833 | Genistein | Genistein results in decreased expression of CYP1B1 mRNA | decreases expression | 12075121 |
| D005839 | Gentamicins | Gentamicins results in increased expression of CYP1B1 mRNA | increases expression | 18172885 |
| D005978 | Glutathione | CYP1B1 protein affects the metabolism of [2-hydroxyestradiol co-treated with Glutathione] | affects cotreatment|affects metabolic processing | 14679015 |
| D005978 | Glutathione | CYP1B1 protein affects the metabolism of [4-hydroxyestradiol-17 beta co-treated with Glutathione] | affects cotreatment|affects metabolic processing | 14679015 |
| C071834 | glycidamide | glycidamide results in decreased expression of CYP1B1 mRNA | decreases expression | 17822822 |
| D012739 | Gonadal Steroid Hormones | CYP1B1 protein polymorphism results in increased metabolism of Gonadal Steroid Hormones | increases metabolic processing | 16006997 |
| C511402 | Grape Seed Proanthocyanidins | Grape Seed Proanthocyanidins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 20146248 |
| C511402 | Grape Seed Proanthocyanidins | Grape Seed Proanthocyanidins inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 20146248 |
| C511402 | Grape Seed Proanthocyanidins | Grape Seed Proanthocyanidins results in decreased expression of CYP1B1 mRNA | decreases expression | 20146248 |
| D006581 | Hexachlorobenzene | Hexachlorobenzene results in increased expression of CYP1B1 mRNA | increases expression | 15159207 |
| D006861 | Hydrogen Peroxide | Hydrogen Peroxide results in increased expression of CYP1B1 mRNA | increases expression | 12414654 |
| C013038 | hydroxyhydroquinone | hydroxyhydroquinone results in increased expression of CYP1B1 mRNA | increases expression | 17572062 |
| C031534 | imperatorin | imperatorin inhibits the reaction [CYP1B1 protein results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol] | decreases reaction|increases oxidation | 15861043 |
| C031534 | imperatorin | imperatorin results in decreased activity of CYP1B1 protein | decreases activity | 15861043 |
| C031534 | imperatorin | imperatorin results in decreased activity of CYP1B1 protein polymorphism | decreases activity | 15861043 |
| C027185 | indirubin | CYP1B1 protein results in increased metabolism of indirubin | increases metabolic processing | 14637189 |
| C027185 | indirubin | indirubin results in increased expression of CYP1B1 mRNA | increases expression | 14637189 |
| C016517 | indole-3-carbinol | [indole-3-carbinol co-treated with DDT] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 17311112 |
| C016517 | indole-3-carbinol | indole-3-carbinol results in increased expression of CYP1B1 mRNA | increases expression | 17311112 15890477 |
| C075954 | indolo(3,2-b)carbazole | indolo(3,2-b)carbazole results in increased expression of CYP1B1 mRNA | increases expression | 18061397 18762178 |
| C075954 | indolo(3,2-b)carbazole | indolo(3,2-b)carbazole results in increased expression of CYP1B1 mRNA | increases expression | 12419834 |
| D007213 | Indomethacin | Indomethacin results in increased expression of CYP1B1 mRNA | increases expression | 16184411 |
| D015056 | 1-Methyl-3-isobutylxanthine | [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 15967407 |
| D015056 | 1-Methyl-3-isobutylxanthine | [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CYP1B1 protein | affects cotreatment|increases expression | 15967407 |
| C055542 | isoimperatorin | isoimperatorin inhibits the reaction [CYP1B1 protein results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol] | decreases reaction|increases oxidation | 15861043 |
| C055542 | isoimperatorin | isoimperatorin results in decreased activity of CYP1B1 protein | decreases activity | 15861043 |
| C055542 | isoimperatorin | isoimperatorin results in decreased activity of CYP1B1 protein polymorphism | decreases activity | 15861043 |
| C015304 | isopimpinellin | isopimpinellin inhibits the reaction [CYP1B1 protein results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol] | decreases reaction|increases oxidation | 15861043 |
| C015304 | isopimpinellin | isopimpinellin results in decreased activity of CYP1B1 protein | decreases activity | 15861043 |
| C015304 | isopimpinellin | isopimpinellin results in decreased activity of CYP1B1 protein polymorphism | decreases activity | 15861043 |
| C016527 | isoquercitrin | isoquercitrin results in decreased activity of CYP1B1 protein | decreases activity | 16271822 |
| C006552 | kaempferol | kaempferol results in decreased activity of CYP1B1 protein | decreases activity | 16271822 |
| C006552 | kaempferol | kaempferol results in decreased expression of CYP1B1 mRNA | decreases expression | 19794518 |
| D007654 | Ketoconazole | Ketoconazole results in decreased activity of CYP1B1 protein | decreases activity | 14709627 |
| C072105 | KN 93 | KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 18089838 |
| C058687 | lansoprazole | lansoprazole results in increased expression of CYP1B1 mRNA | increases expression | 12623754 |
| D001556 | Lindane | Lindane results in decreased expression of CYP1B1 mRNA | decreases expression | 17785943 |
| D008044 | Linuron | Linuron results in increased expression of CYP1B1 mRNA | increases expression | 16040568 |
| C119626 | M 50367 | [M 50367 binds to and results in increased activity of AHR protein] which results in increased activity of CYP1B1 protein | affects binding|increases activity | 18179178 |
| D017258 | Medroxyprogesterone Acetate | CYP1B1 gene polymorphism affects the susceptibility to [Estrogens co-treated with Medroxyprogesterone Acetate] | affects cotreatment|affects response to substance | 15987428 |
| D008550 | Melatonin | 2,4,3',5'-tetramethoxystilbene inhibits the reaction [CYP1B1 protein results in increased hydroxylation of Melatonin] | decreases reaction|increases hydroxylation | 15616152 |
| D008550 | Melatonin | CYP1B1 protein results in increased hydroxylation of Melatonin | increases hydroxylation | 15616152 |
| D008550 | Melatonin | Melatonin results in decreased activity of CYP1B1 protein | decreases activity | 19919601 |
| D008748 | Methylcholanthrene | Methylcholanthrene results in increased expression of CYP1B1 mRNA | increases expression | 15746899 15750580 |
| D008748 | Methylcholanthrene | CYP1B1 protein results in increased chemical synthesis of Methylcholanthrene metabolite | increases chemical synthesis | 11922910 |
| D008748 | Methylcholanthrene | CYP1B1 protein results in increased metabolism of Methylcholanthrene | increases metabolic processing | 11922910 |
| D008748 | Methylcholanthrene | Methylcholanthrene results in increased expression of CYP1B1 mRNA | increases expression | 15582647 20713471 15885734 19141685 |
| D008748 | Methylcholanthrene | Methylcholanthrene results in increased expression of CYP1B1 protein | increases expression | 11922910 |
| D008748 | Methylcholanthrene | Methylcholanthrene results in increased expression of CYP1B1 mRNA | increases expression | 11323195 19889059 |
| D008748 | Methylcholanthrene | Methylcholanthrene results in increased expression of CYP1B1 protein | increases expression | 19889059 |
| D008752 | Methylene Chloride | Methylene Chloride results in decreased expression of CYP1B1 mRNA | decreases expression | 20359517 |
| D015735 | Mifepristone | Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]] | decreases reaction|increases expression|increases reaction | 17690134 |
| D009151 | Mustard Gas | Mustard Gas results in increased expression of CYP1B1 mRNA | increases expression | 15674843 |
| C040015 | myricetin | myricetin results in decreased activity of CYP1B1 protein | decreases activity | 16271822 |
| D037742 | Nanotubes, Carbon | Nanotubes, Carbon results in increased expression of CYP1B1 mRNA | increases expression | 17450800 |
| C498045 | NCX 4040 | NCX 4040 results in decreased activity of CYP1B1 protein | decreases activity | 19542225 |
| C028787 | N-desmethyltamoxifen | N-desmethyltamoxifen results in decreased activity of CYP1B1 protein | decreases activity | 12419016 |
| C022838 | nickel chloride | nickel chloride results in decreased expression of CYP1B1 mRNA | decreases expression | 12839937 |
| C017557 | nickel subsulfide | nickel subsulfide results in decreased expression of CYP1B1 mRNA | decreases expression | 12760830 |
| C062567 | N-methyl-N-2-(methylsulfinyl)ethylpropionic acid amide | CYP1B1 protein results in increased activity of N-methyl-N-2-(methylsulfinyl)ethylpropionic acid amide | increases activity | 15725615 |
| C010262 | norharman | CYP1B1 protein affects the metabolism of [norharman co-treated with aniline] | affects cotreatment|affects metabolic processing | 15279827 |
| C122062 | NSC 674495 | CYP1B1 protein affects the susceptibility to NSC 674495 | affects response to substance | 17674193 |
| C122062 | NSC 674495 | Dactinomycin inhibits the reaction [NSC 674495 results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 11752201 |
| C122062 | NSC 674495 | NSC 674495 results in increased expression of CYP1B1 mRNA | increases expression | 11752201 |
| D019319 | Okadaic Acid | Okadaic Acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | increases expression|increases reaction | 10696073 |
| C026209 | oltipraz | oltipraz results in increased expression of CYP1B1 mRNA | increases expression | 15890477 |
| D009853 | Omeprazole | Omeprazole results in increased expression of CYP1B1 mRNA | increases expression | 12040753 12623754 |
| D010078 | Oxazines | CYP1B1 protein affects the metabolism of Oxazines analog | affects metabolic processing | 20599672 |
| D010126 | Ozone | AHR protein affects the reaction [Ozone results in increased expression of CYP1B1 mRNA] | affects reaction|increases expression | 19536146 |
| D010126 | Ozone | AHR protein affects the reaction [Ozone results in increased expression of CYP1B1 protein] | affects reaction|increases expression | 19536146 |
| D010126 | Ozone | Ozone results in increased expression of CYP1B1 mRNA | increases expression | 19536146 |
| D010126 | Ozone | Ozone results in increased expression of CYP1B1 protein | increases expression | 19536146 |
| C041786 | palm oil | palm oil results in decreased expression of CYP1B1 mRNA | decreases expression | 18042831 |
| D010269 | Paraquat | [17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol co-treated with Paraquat co-treated with Tetrachlorodibenzodioxin] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 17275934 |
| C084656 | paricalcitol | [Phosphorus co-treated with paricalcitol] results in decreased expression of CYP1B1 mRNA | affects cotreatment|decreases expression | 17715259 |
| D052638 | Particulate Matter | Particulate Matter inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 19835593 |
| D052638 | Particulate Matter | Particulate Matter results in decreased expression of CYP1B1 mRNA | decreases expression | 19835593 |
| D052638 | Particulate Matter | Particulate Matter results in decreased expression of CYP1B1 protein | decreases expression | 19835593 |
| D052638 | Particulate Matter | [titanium dioxide co-treated with Particulate Matter] results in decreased expression of CYP1B1 mRNA | affects cotreatment|decreases expression | 19835593 |
| C410127 | PCB 180 | [2,4,4'-trichlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 15808785 |
| C093973 | PD 98059 | PD 98059 inhibits the reaction [AHR protein results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 12758056 |
| C031181 | phenanthrene | CYP1B1 gene polymorphism results in decreased metabolism of phenanthrene | decreases metabolic processing | 17035385 |
| C031181 | phenanthrene | [phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a,l)pyrene co-treated with benzo(b)fluoranthene] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 15566942 |
| D010758 | Phosphorus | [Phosphorus co-treated with paricalcitol] results in decreased expression of CYP1B1 mRNA | affects cotreatment|decreases expression | 17715259 |
| C121565 | pifithrin | pifithrin results in decreased activity of CYP1B1 protein | decreases activity | 16258175 |
| C121565 | pifithrin | pifithrin results in increased expression of CYP1B1 mRNA | increases expression | 16258175 |
| C006253 | pirinixic acid | pirinixic acid results in decreased expression of CYP1B1 mRNA | decreases expression | 16985257 |
| D010936 | Plant Extracts | 3',4'-dimethoxyflavone inhibits the reaction [Plant Extracts results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 19794518 |
| D010936 | Plant Extracts | Plant Extracts results in increased expression of CYP1B1 mRNA | increases expression | 19794518 18061397 |
| D028321 | Plant Preparations | CYP1B1 gene polymorphism affects the susceptibility to Plant Preparations | affects response to substance | 17602170 |
| D011078 | Polychlorinated Biphenyls | Polychlorinated Biphenyls analog results in decreased expression of CYP1B1 mRNA | decreases expression | 16474171 |
| D011078 | Polychlorinated Biphenyls | Polychlorinated Biphenyls analog results in increased expression of CYP1B1 mRNA | increases expression | 16474171 |
| D011078 | Polychlorinated Biphenyls | [Polychlorinated Biphenyls co-treated with polychlorodibenzo-4-dioxin co-treated with chlorinated dibenzofurans] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 15858227 |
| C008954 | polychlorodibenzo-4-dioxin | [polychlorodibenzo-4-dioxin co-treated with chlorinated dibenzofurans] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 17850846 |
| C008954 | polychlorodibenzo-4-dioxin | polychlorodibenzo-4-dioxin results in increased expression of CYP1B1 mRNA | increases expression | 19358281 |
| C008954 | polychlorodibenzo-4-dioxin | [Polychlorinated Biphenyls co-treated with polychlorodibenzo-4-dioxin co-treated with chlorinated dibenzofurans] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 15858227 |
| D011084 | Polycyclic Hydrocarbons, Aromatic | CYP1B1 protein affects the metabolism of Polycyclic Hydrocarbons, Aromatic | affects metabolic processing | 15122594 |
| D011084 | Polycyclic Hydrocarbons, Aromatic | Polycyclic Hydrocarbons, Aromatic results in decreased expression of CYP1B1 mRNA | decreases expression | 15471096 |
| D011084 | Polycyclic Hydrocarbons, Aromatic | Polycyclic Hydrocarbons, Aromatic results in increased expression of CYP1B1 mRNA | increases expression | 15471096 16002475 15278913 |
| D011084 | Polycyclic Hydrocarbons, Aromatic | Polycyclic Hydrocarbons, Aromatic results in increased expression of CYP1B1 protein | increases expression | 15720126 |
| D011319 | Primaquine | Primaquine results in increased expression of CYP1B1 mRNA | increases expression | 12623754 |
| D011374 | Progesterone | Progesterone results in decreased expression of CYP1B1 mRNA | decreases expression | 18037150 |
| C030984 | pyrene | CYP1B1 protein results in increased hydroxylation of pyrene | increases hydroxylation | 15016593 |
| C030984 | pyrene | [phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a,l)pyrene co-treated with benzo(b)fluoranthene] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 15566942 |
| D011794 | Quercetin | Quercetin results in decreased activity of CYP1B1 protein | decreases activity | 16271822 |
| D011794 | Quercetin | Quercetin results in decreased expression of CYP1B1 mRNA | decreases expression | 17637178 |
| D011794 | Quercetin | Quercetin results in increased expression of CYP1B1 mRNA | increases expression | 19794518 |
| D011794 | Quercetin | Quercetin affects the expression of CYP1B1 mRNA | affects expression | 18178720 |
| C012526 | quercitrin | quercitrin results in decreased activity of CYP1B1 protein | decreases activity | 16271822 |
| C059514 | resveratrol | CYP1B1 protein affects the metabolism of resveratrol | affects metabolic processing | 15276085 |
| C059514 | resveratrol | resveratrol affects the expression of CYP1B1 protein | affects expression | 15893423 |
| C059514 | resveratrol | resveratrol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 11279601 15162144 |
| C059514 | resveratrol | resveratrol inhibits the reaction [CYP1B1 protein affects the chemical synthesis of 4-hydroxyestradiol-17 beta] | affects chemical synthesis|decreases reaction | 15142886 |
| C059514 | resveratrol | resveratrol inhibits the reaction [CYP1B1 protein affects the metabolism of Estradiol] | affects metabolic processing|decreases reaction | 15142886 |
| C059514 | resveratrol | resveratrol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1B1 enhancer]] | affects binding|decreases reaction|increases reaction | 19376845 |
| C059514 | resveratrol | resveratrol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ARNT protein binds to CYP1B1 enhancer]] | affects binding|decreases reaction|increases reaction | 19376845 |
| C059514 | resveratrol | resveratrol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein] | decreases reaction|increases activity | 15142886 |
| C059514 | resveratrol | resveratrol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 11279601 19376845 15142886 |
| C059514 | resveratrol | resveratrol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein] | decreases reaction|increases expression | 19138946 |
| C059514 | resveratrol | resveratrol results in decreased expression of CYP1B1 | decreases expression | 15316568 |
| C059514 | resveratrol | resveratrol results in decreased expression of CYP1B1 mRNA | decreases expression | 11279601 15182955 14990334 |
| C059514 | resveratrol | resveratrol results in decreased expression of CYP1B1 protein | decreases expression | 15182955 |
| C028632 | rutecarpine | rutecarpine analog binds to and results in decreased activity of CYP1B1 protein | affects binding|decreases activity | 12852960 |
| D012431 | Rutin | Rutin results in decreased activity of CYP1B1 protein | decreases activity | 16271822 |
| C031060 | salicylamide | salicylamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 14729655 |
| C005705 | sanguinarine | sanguinarine results in increased activity of CYP1B1 protein | increases activity | 15993743 |
| C005705 | sanguinarine | sanguinarine results in increased expression of CYP1B1 mRNA | increases expression | 15993743 |
| C120148 | SIB 1893 | SIB 1893 results in decreased activity of CYP1B1 protein | decreases activity | 15193955 |
| C009277 | sodium arsenate | sodium arsenate results in decreased expression of CYP1B1 mRNA | decreases expression | 11353140 |
| C017947 | sodium arsenite | sodium arsenite results in decreased expression of CYP1B1 mRNA | decreases expression | 12727804 |
| C017947 | sodium arsenite | sodium arsenite results in decreased expression of CYP1B1 mRNA | decreases expression | 11353140 |
| C016104 | sodium bichromate | sodium bichromate results in decreased expression of CYP1B1 mRNA | decreases expression | 12760830 |
| D053260 | Soot | Soot results in increased expression of CYP1B1 mRNA | increases expression | 18684396 |
| C539817 | S-sulindac | S-sulindac inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 19276279 |
| C539817 | S-sulindac | S-sulindac inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 19276279 |
| C539817 | S-sulindac | S-sulindac results in decreased activity of CYP1B1 protein | decreases activity | 19276279 |
| D013267 | Stilbenes | Stilbenes analog inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 18449500 |
| C458525 | STO 609 | STO 609 results in increased expression of CYP1B1 mRNA | increases expression | 18755850 |
| D013467 | Sulindac | Sulindac results in increased expression of CYP1B1 mRNA | increases expression | 17985343 |
| D013467 | Sulindac | Sulindac results in increased activity of CYP1B1 protein | increases activity | 16531450 |
| D013467 | Sulindac | Sulindac results in increased expression of CYP1B1 mRNA | increases expression | 16531450 |
| C025462 | sulindac sulfide | sulindac sulfide results in increased expression of CYP1B1 mRNA | increases expression | 17985343 12734198 |
| D013629 | Tamoxifen | Tamoxifen results in decreased activity of CYP1B1 protein | decreases activity | 12419016 |
| D013629 | Tamoxifen | Tamoxifen results in increased expression of CYP1B1 protein | increases expression | 19812351 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA | increases expression | 19167471 |
| D013749 | Tetrachlorodibenzodioxin | AHRRB protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | affects reaction|increases expression | 19494032 |
| D013749 | Tetrachlorodibenzodioxin | alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 19403181 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA | increases expression | 15716485 19403181 20055451 16443690 16714409 18495758 19494032 18308702 |
| D013749 | Tetrachlorodibenzodioxin | 2,2',4,6'-tetramethoxystilbene inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 19463925 |
| D013749 | Tetrachlorodibenzodioxin | 2,2',4,6'-tetramethoxystilbene inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein] | decreases reaction|increases expression | 19463925 |
| D013749 | Tetrachlorodibenzodioxin | 2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 19276279 |
| D013749 | Tetrachlorodibenzodioxin | 2,4,3',5'-tetramethoxystilbene inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 16120791 |
| D013749 | Tetrachlorodibenzodioxin | 2,4,3',5'-tetramethoxystilbene inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein] | decreases reaction|increases expression | 16120791 |
| D013749 | Tetrachlorodibenzodioxin | 3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein] | decreases reaction|increases activity | 17183067 |
| D013749 | Tetrachlorodibenzodioxin | 3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 17183067 |
| D013749 | Tetrachlorodibenzodioxin | 4-hydroxytamoxifen inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ESR1 protein binds to CYP1B1 promoter]] | affects binding|decreases reaction|increases reaction | 19460354 |
| D013749 | Tetrachlorodibenzodioxin | AHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein] | affects reaction|increases activity | 20171976 |
| D013749 | Tetrachlorodibenzodioxin | AHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | affects reaction|increases expression | 20171976 |
| D013749 | Tetrachlorodibenzodioxin | alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 15075337 19182260 |
| D013749 | Tetrachlorodibenzodioxin | ARNT protein affects the reaction [Tetrachlorodibenzodioxin promotes the reaction [BRCA1 protein binds to CYP1B1 promoter]] | affects binding|affects reaction|increases reaction | 16567799 |
| D013749 | Tetrachlorodibenzodioxin | Azacitidine promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | increases expression|increases reaction | 12927368 |
| D013749 | Tetrachlorodibenzodioxin | benzo(a)pyrene 7,8-dihydrodiol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 21028851 |
| D013749 | Tetrachlorodibenzodioxin | BRCA1 protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | increases expression|increases reaction | 16567799 |
| D013749 | Tetrachlorodibenzodioxin | Calcium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | increases expression|increases reaction | 16237193 |
| D013749 | Tetrachlorodibenzodioxin | calyculin A promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | increases expression|increases reaction | 10696073 |
| D013749 | Tetrachlorodibenzodioxin | Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 19018768 |
| D013749 | Tetrachlorodibenzodioxin | Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein] | decreases reaction|increases expression | 19018768 |
| D013749 | Tetrachlorodibenzodioxin | EP300 protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | affects reaction|increases expression | 18842620 |
| D013749 | Tetrachlorodibenzodioxin | ESR1 protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | increases expression|increases reaction | 19460354 |
| D013749 | Tetrachlorodibenzodioxin | [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 19619570 |
| D013749 | Tetrachlorodibenzodioxin | Estradiol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 15837795 |
| D013749 | Tetrachlorodibenzodioxin | Estradiol promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein] | increases activity|increases reaction | 15157572 |
| D013749 | Tetrachlorodibenzodioxin | Estradiol promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | increases expression|increases reaction | 19619570 |
| D013749 | Tetrachlorodibenzodioxin | Estradiol promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein] | increases expression|increases reaction | 19619570 |
| D013749 | Tetrachlorodibenzodioxin | fluasterone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 12097275 |
| D013749 | Tetrachlorodibenzodioxin | fulvestrant inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ESR1 protein binds to CYP1B1 promoter]] | affects binding|decreases reaction|increases reaction | 19460354 |
| D013749 | Tetrachlorodibenzodioxin | KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 18089838 |
| D013749 | Tetrachlorodibenzodioxin | NCOA2 protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | affects reaction|increases expression | 18842620 |
| D013749 | Tetrachlorodibenzodioxin | Okadaic Acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | increases expression|increases reaction | 10696073 |
| D013749 | Tetrachlorodibenzodioxin | resveratrol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1B1 enhancer]] | affects binding|decreases reaction|increases reaction | 19376845 |
| D013749 | Tetrachlorodibenzodioxin | resveratrol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ARNT protein binds to CYP1B1 enhancer]] | affects binding|decreases reaction|increases reaction | 19376845 |
| D013749 | Tetrachlorodibenzodioxin | resveratrol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein] | decreases reaction|increases activity | 15142886 |
| D013749 | Tetrachlorodibenzodioxin | resveratrol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 15142886 19376845 11279601 |
| D013749 | Tetrachlorodibenzodioxin | resveratrol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein] | decreases reaction|increases expression | 19138946 |
| D013749 | Tetrachlorodibenzodioxin | salicylamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 14729655 |
| D013749 | Tetrachlorodibenzodioxin | [SP1 protein binds to CYP1B1 enhancer] promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | affects binding|increases expression|increases reaction | 12801909 |
| D013749 | Tetrachlorodibenzodioxin | S-sulindac inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 19276279 |
| D013749 | Tetrachlorodibenzodioxin | Stilbenes analog inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 18449500 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin affects the localization of CYP1B1 protein | affects localization | 19138946 |
| D013749 | Tetrachlorodibenzodioxin | [Tetrachlorodibenzodioxin binds to and results in increased activity of AHR protein] which results in increased expression of CYP1B1 mRNA | affects binding|increases activity|increases expression | 14729655 |
| D013749 | Tetrachlorodibenzodioxin | [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 19684285 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin promotes the reaction [[AHR protein binds to ARNT protein] which binds to CYP1B1 enhancer] | affects binding|increases reaction | 12801909 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1B1 enhancer] | affects binding|increases reaction | 18842620 19376845 17785579 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1B1 promoter] | affects binding|increases reaction | 19460354 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin promotes the reaction [ARNT protein binds to CYP1B1 enhancer] | affects binding|increases reaction | 19376845 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin promotes the reaction [ARNT protein binds to CYP1B1 promoter] | affects binding|increases reaction | 16567799 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin promotes the reaction [BRCA1 protein binds to CYP1B1 promoter] | affects binding|increases reaction | 16567799 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin promotes the reaction [EP300 protein binds to CYP1B1 enhancer] | affects binding|increases reaction | 18842620 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin promotes the reaction [EP300 protein binds to CYP1B1 promoter] | affects binding|increases reaction | 18842620 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin promotes the reaction [ESR1 protein binds to CYP1B1 promoter] | affects binding|increases reaction | 19460354 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin promotes the reaction [NCOA1 protein binds to CYP1B1 enhancer] | affects binding|increases reaction | 18842620 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin promotes the reaction [NCOA1 protein binds to CYP1B1 promoter] | affects binding|increases reaction | 18842620 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin promotes the reaction [NCOA2 protein binds to CYP1B1 enhancer] | affects binding|increases reaction | 18842620 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin promotes the reaction [NCOA2 protein binds to CYP1B1 promoter] | affects binding|increases reaction | 18842620 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin promotes the reaction [SMARCA4 protein binds to CYP1B1 enhancer] | affects binding|increases reaction | 18842620 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin promotes the reaction [SMARCA4 protein binds to CYP1B1 promoter] | affects binding|increases reaction | 18842620 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in decreased expression of CYP1B1 mRNA | decreases expression | 17101203 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein | increases activity | 17183067 15157572 14637189 20171976 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA | increases expression | 19018768 19358281 14729655 19376845 16258175 21028851 19901195 19182260 15837795 16120791 17517823 12377990 9920887 19619570 15953582 16527260 15075337 17257637 16985168 16697128 17183067 12801909 12097275 15157572 16704738 18755850 20106945 10696073 15041469 16271822 18762178 18061397 19276279 17785579 18842620 12727795 11162886 19463925 19324859 15093275 18449500 12927368 15596250 11728381 11358810 19684285 19755661 11294972 17968679 20171976 18089838 11368318 11452143 19041851 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA polymorphism | increases expression | 15596250 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein | increases expression | 20171976 19138946 16120791 16237193 15953582 19018768 19463925 19324859 11452143 |
| D013749 | Tetrachlorodibenzodioxin | Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 11728381 |
| D013749 | Tetrachlorodibenzodioxin | Tretinoin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 15075337 |
| D013749 | Tetrachlorodibenzodioxin | trichostatin A promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | increases expression|increases reaction | 12927368 |
| D013749 | Tetrachlorodibenzodioxin | Zearalenone promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein] | increases activity|increases reaction | 15157572 |
| D013749 | Tetrachlorodibenzodioxin | 3'-methoxy-4'-nitroflavone inhibits the reaction [AHR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]] | decreases reaction|increases expression|increases reaction | 15183014 |
| D013749 | Tetrachlorodibenzodioxin | 3'-methoxy-4'-nitroflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein] | decreases reaction|increases expression | 15050417 |
| D013749 | Tetrachlorodibenzodioxin | AHR gene mutant form inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 16984957 |
| D013749 | Tetrachlorodibenzodioxin | AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CYP1B1 mRNA] | decreases expression|decreases reaction | 14728982 |
| D013749 | Tetrachlorodibenzodioxin | AHR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein] | increases expression|increases reaction | 15183014 |
| D013749 | Tetrachlorodibenzodioxin | PER1 protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | affects reaction|increases expression | 19038280 |
| D013749 | Tetrachlorodibenzodioxin | PER2 protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | affects reaction|increases expression | 19038280 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin affects the expression of CYP1B1 mRNA | affects expression | 15037607 |
| D013749 | Tetrachlorodibenzodioxin | [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of CYP1B1 mRNA | affects binding|increases expression | 16214954 |
| D013749 | Tetrachlorodibenzodioxin | [Tetrachlorodibenzodioxin co-treated with Dietary Fats] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 20435547 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1B1 promoter] | affects binding|increases reaction | 19282623 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in decreased expression of CYP1B1 mRNA | decreases expression | 14728982 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA | increases expression | 12859982 16929009 14505802 16984957 11559018 15667827 18163543 18606429 16102516 15967407 18850075 20007409 18434241 19933214 18372398 17715397 19684285 16962184 14728982 16120747 19141685 19038280 17997381 20435547 18796159 15328365 19750107 16922920 17035482 20159946 17337447 15537747 18691609 17586704 16114106 19897914 15056816 18334230 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein | increases expression | 19490989 15537747 15183014 12859982 12758056 15050417 17997381 |
| D013749 | Tetrachlorodibenzodioxin | [17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol co-treated with Paraquat co-treated with Tetrachlorodibenzodioxin] results in increased expression of CYP1B1 mRNA | affects cotreatment|increases expression | 17275934 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA | increases expression | 17275934 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of CYP1B1 | increases expression | 15993909 |
| D013749 | Tetrachlorodibenzodioxin | AHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | affects reaction|increases expression | 19497421 |
| D013749 | Tetrachlorodibenzodioxin | Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | increases expression|increases reaction | 17690134 |
| D013749 | Tetrachlorodibenzodioxin | Drugs, Chinese Herbal promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | increases expression|increases reaction | 16901605 |
| D013749 | Tetrachlorodibenzodioxin | Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]] | decreases reaction|increases expression|increases reaction | 17690134 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin promotes the reaction [[AHR protein binds to ARNT protein] which binds to CYP1B1 enhancer] | affects binding|increases reaction | 12859982 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein] | increases expression|increases reaction | 16198082 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein | increases activity | 19497421 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA | increases expression | 16054898 19490992 11559018 15644576 17690134 11500237 10910964 18796159 12859982 16198082 18990726 16984957 17557910 18465118 18178546 16901605 19497421 19969063 12060831 12223220 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein | increases expression | 17557910 16237193 20412032 9144388 |
| D013749 | Tetrachlorodibenzodioxin | TNF protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | increases expression|increases reaction | 17557910 |
| D013749 | Tetrachlorodibenzodioxin | TNF protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein] | increases expression|increases reaction | 17557910 |
| D013755 | Tetradecanoylphorbol Acetate | Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 11728381 |
| C009495 | titanium dioxide | [titanium dioxide co-treated with Particulate Matter] results in decreased expression of CYP1B1 mRNA | affects cotreatment|decreases expression | 19835593 |
| D014028 | Tobacco Smoke Pollution | Tobacco Smoke Pollution results in increased expression of CYP1B1 mRNA | increases expression | 20951464 18684396 19576839 16996243 |
| D014028 | Tobacco Smoke Pollution | Tobacco Smoke Pollution results in increased expression of CYP1B1 protein | increases expression | 16996243 |
| D014028 | Tobacco Smoke Pollution | Tobacco Smoke Pollution results in increased expression of CYP1B1 mRNA | increases expression | 19141685 |
| D014050 | Toluene | Toluene results in decreased expression of CYP1B1 mRNA | decreases expression | 20359517 |
| C507866 | trans-1,2-dihydro-1,2-naphthalenediol | CYP1B1 protein results in increased abundance of trans-1,2-dihydro-1,2-naphthalenediol | increases abundance | 16243959 |
| D014212 | Tretinoin | Tretinoin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 15075337 |
| D014212 | Tretinoin | Tretinoin results in increased expression of CYP1B1 mRNA | increases expression | 12870655 16985168 |
| D014241 | Trichloroethylene | Trichloroethylene results in decreased expression of CYP1B1 mRNA | decreases expression | 20359517 |
| C012589 | trichostatin A | trichostatin A inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 15713371 |
| C012589 | trichostatin A | trichostatin A promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | increases expression|increases reaction | 12927368 |
| C012589 | trichostatin A | trichostatin A results in increased expression of CYP1B1 mRNA | increases expression | 12927368 |
| D001335 | Vehicle Emissions | Vehicle Emissions results in increased expression of CYP1B1 mRNA | increases expression | 18684396 |
| D001335 | Vehicle Emissions | Vehicle Emissions results in increased expression of CYP1B1 mRNA | increases expression | 19465080 |
| D014801 | Vitamin A | CYP1B1 protein results in increased oxidation of Vitamin A | increases oxidation | 15258110 |
| D014801 | Vitamin A | CYP1B1 protein results in increased oxidation of Vitamin A | increases oxidation | 15258110 |
| D024483 | Vitamin K 3 | Vitamin K 3 results in increased expression of CYP1B1 mRNA | increases expression | 12414654 |
| C111237 | vorinostat | vorinostat inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] | decreases reaction|increases expression | 15713371 |
| D015215 | Zidovudine | [Zidovudine co-treated with IFNA1 protein] results in decreased expression of CYP1B1 mRNA | affects cotreatment|decreases expression | 20370541 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000008 | Abdominal Neoplasms | Sulindac | 8.74 | 14745880 | |
| MESH:D000008 | Abdominal Neoplasms | Tamoxifen | 8.74 | 14745880 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Diethylhexyl Phthalate | 4.62 | 6734493 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Tetrachlorodibenzodioxin | 4.62 | 14514962 15322242 11752688 | |
| MESH:D000015 | Abnormalities, Multiple | Vitamin A | 3.69 | 10992263 | |
| MESH:D000038 | Abscess | Drugs, Chinese Herbal | 5.01 | 15043669 | |
| MESH:D000052 | Acanthosis Nigricans | diethyl phthalate | 6.13 | 12616302 | |
| MESH:D000138 | Acidosis | Ammonium Chloride | 2.30 | 18287403 | |
| MESH:D000152 | Acne Vulgaris | Ethinyl Estradiol | 2.65 | 17505938 | |
| MESH:D000163 | Acquired Immunodeficiency Syndrome | Zidovudine | 3.58 | 9612607 | |
| MESH:D058186 | Acute Kidney Injury | Gentamicins | 11.14 | 11274264 | |
| MESH:D058186 | Acute Kidney Injury | pifithrin | 11.14 | 17670903 | |
| MESH:D058186 | Acute Kidney Injury | resveratrol | 11.14 | 16538975 | |
| MESH:D058186 | Acute Kidney Injury | Sulindac | 11.14 | 7897758 | |
| MESH:D055371 | Acute Lung Injury | Particulate Matter | 5.53 | 12396868 | |
| MESH:D055371 | Acute Lung Injury | pirinixic acid | 5.53 | 18653653 | |
| MESH:D000230 | Adenocarcinoma | 9,10-Dimethyl-1,2-benzanthracene | 17.01 | 10697514 12844480 | |
| MESH:D000230 | Adenocarcinoma | arsenic trioxide | 17.01 | 11798837 19825857 | |
| MESH:D000230 | Adenocarcinoma | Benzo(a)pyrene | 17.01 | 20127859 20464547 | |
| MESH:D000230 | Adenocarcinoma | daidzein | 17.01 | 11473722 | |
| MESH:D000230 | Adenocarcinoma | Estradiol | 17.01 | 11473722 | |
| MESH:D000230 | Adenocarcinoma | Ethinyl Estradiol | 17.01 | 14692618 | |
| MESH:D000230 | Adenocarcinoma | Genistein | 17.01 | 11473722 | |
| MESH:D000230 | Adenocarcinoma | Indomethacin | 17.01 | 16537180 | |
| MESH:D000230 | Adenocarcinoma | Sulindac | 17.01 | 11910360 | |
| MESH:D002282 | Adenocarcinoma, Bronchiolo-Alveolar | Tobacco Smoke Pollution | 4.23 | 15814487 | |
| MESH:D000236 | Adenoma | marker/mechanism | 11376689 | ||
| MESH:D000236 | Adenoma | 2-Acetylaminofluorene | 32.38 | 10737359 | |
| MESH:D000236 | Adenoma | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 32.38 | 16176798 | |
| MESH:D000236 | Adenoma | 9,10-Dimethyl-1,2-benzanthracene | 32.38 | 11376689 | |
| MESH:D000236 | Adenoma | Benzo(a)pyrene | 32.38 | 6695378 | |
| MESH:D000236 | Adenoma | beta-Naphthoflavone | 32.38 | 19389873 | |
| MESH:D000236 | Adenoma | Diethylnitrosamine | 32.38 | 10737359 6695378 | |
| MESH:D000236 | Adenoma | Indomethacin | 32.38 | 11497255 | |
| MESH:D000236 | Adenoma | Melatonin | 32.38 | 17195641 | |
| MESH:D000236 | Adenoma | Methylcholanthrene | 32.38 | 10545420 6695378 | |
| MESH:D000236 | Adenoma | resveratrol | 32.38 | 15688382 | |
| MESH:D000236 | Adenoma | Sulindac | 32.38 | 10223192 | |
| MESH:D002759 | Adenoma, Bile Duct | 2-Acetylaminofluorene | 4.71 | 6705139 | |
| MESH:D018248 | Adenoma, Liver Cell | 3,4,5,3',4'-pentachlorobiphenyl | 24.69 | 16628245 | |
| MESH:D018248 | Adenoma, Liver Cell | DDT | 24.69 | 12597452 | |
| MESH:D018248 | Adenoma, Liver Cell | Diethylnitrosamine | 24.69 | 17162532 17620307 16434500 19061943 18056438 19052882 | |
| MESH:D018248 | Adenoma, Liver Cell | diethyl phthalate | 24.69 | 12616302 | |
| MESH:D018248 | Adenoma, Liver Cell | pirinixic acid | 24.69 | 16434500 | |
| MESH:D018248 | Adenoma, Liver Cell | Tetrachlorodibenzodioxin | 24.69 | 16835633 | |
| MESH:D011125 | Adenomatous Polyposis Coli | Sulindac | 3.45 | 19003578 11874996 11535846 12394442 17611924 15623613 16460482 | |
| MESH:D000310 | Adrenal Gland Neoplasms | sodium arsenite | 3.40 | 15276417 | |
| MESH:D018246 | Adrenocortical Adenoma | sodium arsenite | 3.60 | 16712894 17306315 | |
| MESH:D000382 | Agricultural Workers' Diseases | 2,4-Dichlorophenoxyacetic Acid | 13.70 | 16132792 | |
| MESH:D000382 | Agricultural Workers' Diseases | DDT | 13.70 | 16487989 12584743 | |
| MESH:D000382 | Agricultural Workers' Diseases | Dichlorodiphenyl Dichloroethylene | 13.70 | 16487989 | |
| MESH:D000382 | Agricultural Workers' Diseases | Lindane | 13.70 | 12661182 | |
| MESH:D000382 | Agricultural Workers' Diseases | Paraquat | 13.70 | 11874814 | |
| MESH:D019973 | Alcohol-Related Disorders | Curcumin | 3.79 | 17887948 | |
| MESH:D000505 | Alopecia | Tretinoin | 2.53 | 15955085 | |
| MESH:D016301 | Alveolar Bone Loss | Indomethacin | 4.07 | 17225004 | |
| MESH:D000544 | Alzheimer Disease | Curcumin | 10.88 | 15590663 | |
| MESH:D000544 | Alzheimer Disease | Indomethacin | 10.88 | 15579461 17627676 | |
| MESH:D000544 | Alzheimer Disease | Ozone | 10.88 | 15513908 | |
| MESH:D000544 | Alzheimer Disease | Particulate Matter | 10.88 | 15513908 | |
| MESH:D000544 | Alzheimer Disease | Plant Extracts | 10.88 | 16962711 | |
| MESH:D000544 | Alzheimer Disease | resveratrol | 10.88 | 16183991 16162502 | |
| MESH:D000544 | Alzheimer Disease | sulindac sulfide | 10.88 | 18759972 | |
| MESH:D000686 | Amyloidosis | Diethylstilbestrol | 3.25 | 15469931 | |
| MESH:D000690 | Amyotrophic Lateral Sclerosis | 4-hydroxy-2-nonenal | 3.17 | 10965797 | |
| MESH:D000740 | Anemia | Drugs, Chinese Herbal | 8.42 | 17963324 15504547 | |
| MESH:D000740 | Anemia | Tetrachlorodibenzodioxin | 8.42 | 11748828 | |
| MESH:D000740 | Anemia | Vitamin A | 8.42 | 16960172 | |
| MESH:D000741 | Anemia, Aplastic | Benzene | 3.29 | 11369114 17661222 14761424 | |
| MESH:D000743 | Anemia, Hemolytic | Quercetin | 3.07 | 17084956 | |
| MESH:D018798 | Anemia, Iron-Deficiency | Vitamin A | 3.65 | 16960172 | |
| MESH:D000787 | Angina Pectoris | Drugs, Chinese Herbal | 4.13 | 11477813 | |
| MESH:D001004 | Anus Diseases | Drugs, Chinese Herbal | 4.67 | 15043669 | |
| MESH:D001014 | Aortic Aneurysm | Indomethacin | 3.62 | 10231640 | |
| MESH:D017544 | Aortic Aneurysm, Abdominal | Benzo(a)pyrene | 7.56 | 19183758 | |
| MESH:D017544 | Aortic Aneurysm, Abdominal | Indomethacin | 7.56 | 10388637 | |
| MESH:D001161 | Arteriosclerosis | Cyclophosphamide | 9.92 | 15014928 | |
| MESH:D001161 | Arteriosclerosis | Dietary Fats | 9.92 | 15238619 | |
| MESH:D001161 | Arteriosclerosis | Ethinyl Estradiol | 9.92 | 11256880 | |
| MESH:D018771 | Arthralgia | Indomethacin | 3.87 | 2160914 | |
| MESH:D001169 | Arthritis, Experimental | Dexamethasone | 12.99 | 17659584 | |
| MESH:D001169 | Arthritis, Experimental | Ethinyl Estradiol | 12.99 | 15885639 | |
| MESH:D001169 | Arthritis, Experimental | Plant Extracts | 12.99 | 14686799 | |
| MESH:D001169 | Arthritis, Experimental | resveratrol | 12.99 | 17115116 | |
| MESH:D001169 | Arthritis, Experimental | Tretinoin | 12.99 | 16412693 | |
| MESH:D015210 | Arthritis, Gouty | Drugs, Chinese Herbal | 4.47 | 19655406 | |
| MESH:D001172 | Arthritis, Rheumatoid | Curcumin | 8.02 | 16807698 | |
| MESH:D001172 | Arthritis, Rheumatoid | Indomethacin | 8.02 | 11248219 | |
| MESH:D001172 | Arthritis, Rheumatoid | Ozone | 8.02 | 15570426 | |
| MESH:D001172 | Arthritis, Rheumatoid | Tobacco Smoke Pollution | 8.02 | 19898480 | |
| MESH:D001172 | Arthritis, Rheumatoid | Tretinoin | 8.02 | 16292516 | |
| MESH:D001249 | Asthma | Mustard Gas | 6.02 | 10378619 | |
| MESH:D001249 | Asthma | Ozone | 6.02 | 17854713 16373670 | |
| MESH:D001249 | Asthma | Tretinoin | 6.02 | 16456186 | |
| MESH:D001249 | Asthma | Vitamin A | 6.02 | 16732791 | |
| MESH:D001260 | Ataxia Telangiectasia | Quercetin | 3.70 | 15336622 | |
| MESH:D050197 | Atherosclerosis | Curcumin | 5.78 | 18704882 | |
| MESH:D050197 | Atherosclerosis | Methylcholanthrene | 5.78 | 11922910 | |
| MESH:D050197 | Atherosclerosis | resveratrol | 5.78 | 17967414 16873680 | |
| MESH:D001284 | Atrophy | fulvestrant | 3.63 | 11514358 | |
| MESH:D001321 | Autistic Disorder | Arachidonic Acid | 2.46 | 18582451 | |
| MESH:D001321 | Autistic Disorder | Glutathione | 2.46 | 16917939 18929414 19056591 19267885 | |
| MESH:D001321 | Autistic Disorder | Melatonin | 2.46 | 16919138 16897403 | |
| MESH:D001327 | Autoimmune Diseases | Curcumin | 6.74 | 19761891 | |
| MESH:D001327 | Autoimmune Diseases | Quercetin | 6.74 | 19761891 | |
| MESH:D001471 | Barrett Esophagus | Tretinoin | 3.17 | 16935849 | |
| MESH:D001477 | Bartter Syndrome | Indomethacin | 3.73 | 10684365 | |
| MESH:D001768 | Blister | Mustard Gas | 3.88 | 19167455 | |
| MESH:D001778 | Blood Coagulation Disorders | arsenic trioxide | 16.55 | 16206674 | |
| MESH:D001778 | Blood Coagulation Disorders | Omeprazole | 16.55 | 19483382 | |
| MESH:D001778 | Blood Coagulation Disorders | pirinixic acid | 16.55 | 19483382 | |
| MESH:D001778 | Blood Coagulation Disorders | Tetrachlorodibenzodioxin | 16.55 | 12125929 | |
| MESH:D001778 | Blood Coagulation Disorders | Tretinoin | 16.55 | 16206674 16197459 | |
| MESH:D001836 | Body Weight Changes | 2-xylene | 7.83 | 7457028 | |
| MESH:D001836 | Body Weight Changes | Tetrachlorodibenzodioxin | 7.83 | 15340226 | |
| MESH:D001848 | Bone Diseases, Developmental | Tetrachlorodibenzodioxin | 1.80 | 15746008 | |
| MESH:D001855 | Bone Marrow Diseases | Benzene | 3.94 | 16183116 | |
| MESH:D019046 | Bone Marrow Neoplasms | Dactinomycin | 4.25 | 14601052 | |
| MESH:D001862 | Bone Resorption | bisphenol A | 5.95 | 11985600 | |
| MESH:D001862 | Bone Resorption | Drugs, Chinese Herbal | 5.95 | 9881647 | |
| MESH:D001913 | Bowen's Disease | Sulindac | 4.06 | 11207687 | |
| MESH:D001929 | Brain Edema | Indomethacin | 3.73 | 11481608 | |
| MESH:D020201 | Brain Hemorrhage, Traumatic | Progesterone | 4.04 | 17868700 | |
| MESH:D001930 | Brain Injuries | Progesterone | 3.01 | 15665606 15845082 15380490 | |
| MESH:D002545 | Brain Ischemia | Curcumin | 14.02 | 16770732 | |
| MESH:D002545 | Brain Ischemia | Indomethacin | 14.02 | 12524144 | |
| MESH:D002545 | Brain Ischemia | Plant Extracts | 14.02 | 16041641 | |
| MESH:D002545 | Brain Ischemia | resveratrol | 14.02 | 17600658 | |
| MESH:D001932 | Brain Neoplasms | Curcumin | 2.82 | 17596214 | |
| MESH:D001943 | Breast Neoplasms | marker/mechanism | 16298037 17297925 | ||
| MESH:D001943 | Breast Neoplasms | 2,4-diaminotoluene | 54.55 | 11921183 | |
| MESH:D001943 | Breast Neoplasms | 2-hydroxyestradiol | 54.55 | 16675129 | |
| MESH:D001943 | Breast Neoplasms | 4-hydroxyestradiol-17 beta | 54.55 | 16675129 | |
| MESH:D001943 | Breast Neoplasms | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 54.55 | 20146248 | |
| MESH:D001943 | Breast Neoplasms | 9,10-Dimethyl-1,2-benzanthracene | 54.55 | 16153821 20435547 15565634 17127718 18840765 | |
| MESH:D001943 | Breast Neoplasms | allyl sulfide | 54.55 | 17125941 | |
| MESH:D001943 | Breast Neoplasms | Apigenin | 54.55 | 17132221 16541309 | |
| MESH:D001943 | Breast Neoplasms | Benzene | 54.55 | 17162533 11921183 | |
| MESH:D001943 | Breast Neoplasms | Benzo(a)pyrene | 54.55 | 20146248 17474063 | |
| MESH:D001943 | Breast Neoplasms | bexarotene | 54.55 | 16344269 16818667 | |
| MESH:D001943 | Breast Neoplasms | bisphenol A | 54.55 | 17123778 | |
| MESH:D001943 | Breast Neoplasms | Curcumin | 54.55 | 19250217 18462866 18593918 16243823 | |
| MESH:D001943 | Breast Neoplasms | Cyclophosphamide | 54.55 | 18234424 18323546 17388661 15136595 11325840 12006526 15093573 17020986 16978400 | |
| MESH:D001943 | Breast Neoplasms | DDT | 54.55 | 12709520 16792888 | |
| MESH:D001943 | Breast Neoplasms | decitabine | 54.55 | 18320071 19208741 | |
| MESH:D001943 | Breast Neoplasms | Dichlorodiphenyl Dichloroethylene | 54.55 | 15061365 | |
| MESH:D001943 | Breast Neoplasms | Dieldrin | 54.55 | 15770527 11859874 | |
| MESH:D001943 | Breast Neoplasms | Dietary Fats | 54.55 | 20435547 | |
| MESH:D001943 | Breast Neoplasms | Diethylnitrosamine | 54.55 | 17474063 | |
| MESH:D001943 | Breast Neoplasms | Diethylstilbestrol | 54.55 | 17129689 15324884 | |
| MESH:D001943 | Breast Neoplasms | docetaxel | 54.55 | 19526202 15567936 16495393 15692762 17369602 16264153 18628466 | |
| MESH:D001943 | Breast Neoplasms | Estradiol | 54.55 | 12948864 17289903 14630087 19861407 17018787 16675129 18497071 17261762 | |
| MESH:D001943 | Breast Neoplasms | fulvestrant | 54.55 | 18984771 | |
| MESH:D001943 | Breast Neoplasms | Genistein | 54.55 | 17200150 16873071 16541309 | |
| MESH:D001943 | Breast Neoplasms | Grape Seed Proanthocyanidins | 54.55 | 20146248 | |
| MESH:D001943 | Breast Neoplasms | Hexachlorobenzene | 54.55 | 15061365 12709520 | |
| MESH:D001943 | Breast Neoplasms | indole-3-carbinol | 54.55 | 16082211 | |
| MESH:D001943 | Breast Neoplasms | Indomethacin | 54.55 | 17401462 | |
| MESH:D001943 | Breast Neoplasms | kaempferol | 54.55 | 16756079 | |
| MESH:D001943 | Breast Neoplasms | Lindane | 54.55 | 14688026 | |
| MESH:D001943 | Breast Neoplasms | Methylcholanthrene | 54.55 | 17474063 | |
| MESH:D001943 | Breast Neoplasms | Methylene Chloride | 54.55 | 15986119 | |
| MESH:D001943 | Breast Neoplasms | Plant Preparations | 54.55 | 17398067 | |
| MESH:D001943 | Breast Neoplasms | Progesterone | 54.55 | 16175315 15562024 17614352 | |
| MESH:D001943 | Breast Neoplasms | Quercetin | 54.55 | 18628248 | |
| MESH:D001943 | Breast Neoplasms | resveratrol | 54.55 | 17534123 16393696 17651959 | |
| MESH:D001943 | Breast Neoplasms | Sulindac | 54.55 | 16642371 | |
| MESH:D001943 | Breast Neoplasms | Tamoxifen | 54.55 | 18997820 19011961 19288272 19221464 21152245 18855134 19289846 18815881 19410462 17893378 17261762 18629630 18821012 19142967 17440819 18351453 20544844 19189210 18425577 19189212 19200415 16202921 17049068 19084267 20859285 16818667 20390343 19155303 18984771 11161223 20065188 19059307 16873071 17242785 20005174 20135344 15565566 19066611 19487384 19244106 19115204 16273361 19103187 21138602 15668708 | |
| MESH:D001943 | Breast Neoplasms | Tetrachlorodibenzodioxin | 54.55 | 20435547 | |
| MESH:D001943 | Breast Neoplasms | Tretinoin | 54.55 | 16443354 16166294 16873071 | |
| MESH:D001943 | Breast Neoplasms | Trichloroethylene | 54.55 | 15986119 | |
| MESH:D001943 | Breast Neoplasms | vorinostat | 54.55 | 16144943 | |
| MESH:D016535 | Bronchial Hyperreactivity | Ozone | 2.61 | 16777450 14754758 17626835 19059883 18315731 15516495 18417511 | |
| MESH:D001989 | Bronchiolitis Obliterans | Mustard Gas | 3.88 | 15286001 | |
| MESH:D029481 | Bronchitis, Chronic | Mustard Gas | 3.68 | 17687719 10378619 | |
| MESH:D001997 | Bronchopulmonary Dysplasia | Tretinoin | 8.80 | 16813970 | |
| MESH:D001997 | Bronchopulmonary Dysplasia | Vitamin A | 8.80 | 17426644 17377406 | |
| MESH:D002051 | Burkitt Lymphoma | arsenic trioxide | 3.12 | 11589617 | |
| MESH:D002056 | Burns | Indomethacin | 3.46 | 10459503 | |
| MESH:D002057 | Burns, Chemical | Plant Extracts | 4.04 | 9625245 | |
| MESH:D002100 | Cachexia | Indomethacin | 8.18 | 15625704 15141370 16537180 11239499 | |
| MESH:D002100 | Cachexia | Ozone | 8.18 | 16183385 | |
| MESH:D002105 | Cadmium Poisoning | Quercetin | 4.25 | 16962696 | |
| MESH:D002181 | Candidiasis, Vulvovaginal | Estradiol | 3.19 | 16111702 | |
| MESH:D002252 | Carbon Tetrachloride Poisoning | Carbon Tetrachloride | 6.33 | 16124888 16227642 3786805 15673190 16192424 15700767 10355542 15721981 16097048 18705752 16050911 16011737 | |
| MESH:D002252 | Carbon Tetrachloride Poisoning | Melatonin | 6.33 | 15700767 | |
| MESH:D002277 | Carcinoma | andrographolide | 11.19 | 19426720 | |
| MESH:D002277 | Carcinoma | Curcumin | 11.19 | 18593918 | |
| MESH:D002277 | Carcinoma | Methylcholanthrene | 11.19 | 10545420 | |
| MESH:D002277 | Carcinoma | Tetrachlorodibenzodioxin | 11.19 | 16835633 | |
| MESH:D018270 | Carcinoma, Ductal, Breast | Tamoxifen | 3.25 | 19066611 | |
| MESH:D018236 | Carcinoma, Embryonal | Tretinoin | 3.86 | 16168501 | |
| MESH:D006528 | Carcinoma, Hepatocellular | 2-Acetylaminofluorene | 32.25 | 10737359 6705139 3581430 17761372 3084413 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Aflatoxin B1 | 32.25 | 21507988 12907637 12619106 | |
| MESH:D006528 | Carcinoma, Hepatocellular | arsenic trioxide | 32.25 | 15073043 14691202 15553829 16217749 11135700 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Carbon Tetrachloride | 32.25 | 18788625 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Cyclophosphamide | 32.25 | 19701751 | |
| MESH:D006528 | Carcinoma, Hepatocellular | DDT | 32.25 | 12597452 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Diethylnitrosamine | 32.25 | 19171122 20101231 19107877 18978308 16878318 20432363 19383236 11831363 18393292 16698587 18788625 16681979 16569478 20524982 20514400 17428255 17162532 16540662 19418558 16830150 18665156 18056438 20727157 18494052 19052882 20935162 16935385 18785209 17978847 16807293 20512989 19519916 17138121 20084675 18210153 19394651 10737359 18691550 18971187 20007298 16502159 19335982 16328049 19539802 3084413 21159647 17055752 18506893 10672840 19822196 19208518 19701751 20214788 3581430 17761372 17173139 19919837 16779866 16288022 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Diethylstilbestrol | 32.25 | 15948411 16924424 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Estradiol | 32.25 | 16924424 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Estrogens | 32.25 | 15341023 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Genistein | 32.25 | 16924424 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Indomethacin | 32.25 | 16391822 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Plant Extracts | 32.25 | 18834353 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Quercetin | 32.25 | 12508355 19519916 | |
| MESH:D006528 | Carcinoma, Hepatocellular | resveratrol | 32.25 | 19321006 16227395 | |
| MESH:D006528 | Carcinoma, Hepatocellular | sodium arsenite | 32.25 | 17306315 15276417 16507464 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Tamoxifen | 32.25 | 16924424 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Tretinoin | 32.25 | 1917145 | |
| MESH:D002278 | Carcinoma in Situ | bisphenol A | 3.71 | 17123778 | |
| MESH:D018827 | Carcinoma, Lewis Lung | Cyclophosphamide | 11.80 | 16152834 | |
| MESH:D018827 | Carcinoma, Lewis Lung | Indomethacin | 11.80 | 11053908 | |
| MESH:D018827 | Carcinoma, Lewis Lung | resveratrol | 11.80 | 16675471 | |
| MESH:D018276 | Carcinoma, Medullary | Indomethacin | 4.07 | 14736730 11352223 18791128 | |
| MESH:D002289 | Carcinoma, Non-Small-Cell Lung | bexarotene | 9.44 | 16247446 | |
| MESH:D002289 | Carcinoma, Non-Small-Cell Lung | Curcumin | 9.44 | 18414057 | |
| MESH:D002289 | Carcinoma, Non-Small-Cell Lung | docetaxel | 9.44 | 11894018 | |
| MESH:D002289 | Carcinoma, Non-Small-Cell Lung | sulindac sulfide | 9.44 | 12391285 | |
| MESH:D002289 | Carcinoma, Non-Small-Cell Lung | Tobacco Smoke Pollution | 9.44 | 11212258 | |
| MESH:D021441 | Carcinoma, Pancreatic Ductal | Quercetin | 3.70 | 17234771 | |
| MESH:D002291 | Carcinoma, Papillary | arsenic trioxide | 3.58 | 19014326 | |
| MESH:D002292 | Carcinoma, Renal Cell | Cyclophosphamide | 4.24 | 16201981 | |
| MESH:D002292 | Carcinoma, Renal Cell | Indomethacin | 4.24 | 17341418 | |
| MESH:D018288 | Carcinoma, Small Cell | arsenic trioxide | 2.95 | 12490120 | |
| MESH:D002294 | Carcinoma, Squamous Cell | 9,10-Dimethyl-1,2-benzanthracene | 26.38 | 11376689 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Benzo(a)pyrene | 26.38 | 20419170 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Curcumin | 26.38 | 18462866 | |
| MESH:D002294 | Carcinoma, Squamous Cell | decitabine | 26.38 | 19215824 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Glutathione | 26.38 | 17015178 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Indomethacin | 26.38 | 12636206 15482327 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Plant Preparations | 26.38 | 17418620 | |
| MESH:D002294 | Carcinoma, Squamous Cell | resveratrol | 26.38 | 16227395 | |
| MESH:D002294 | Carcinoma, Squamous Cell | sodium arsenite | 26.38 | 18572023 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Tetradecanoylphorbol Acetate | 26.38 | 18922899 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Tobacco Smoke Pollution | 26.38 | 11212258 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Tretinoin | 26.38 | 16051514 16096774 | |
| MESH:D002295 | Carcinoma, Transitional Cell | Tamoxifen | 2.47 | 17572228 | |
| MESH:D006332 | Cardiomegaly | Plant Extracts | 6.31 | 17645561 | |
| MESH:D006332 | Cardiomegaly | Quercetin | 6.31 | 19794523 | |
| MESH:D006332 | Cardiomegaly | Tetrachlorodibenzodioxin | 6.31 | 18670907 18850075 16120746 | |
| MESH:D002318 | Cardiovascular Diseases | daidzein | 18.88 | 16332659 | |
| MESH:D002318 | Cardiovascular Diseases | Genistein | 18.88 | 16332659 | |
| MESH:D002318 | Cardiovascular Diseases | Hydrogen Peroxide | 18.88 | 16936243 | |
| MESH:D002318 | Cardiovascular Diseases | kaempferol | 18.88 | 16756079 | |
| MESH:D002318 | Cardiovascular Diseases | Particulate Matter | 18.88 | 12396868 | |
| MESH:D002318 | Cardiovascular Diseases | Plant Preparations | 18.88 | 16862667 | |
| MESH:D002318 | Cardiovascular Diseases | resveratrol | 18.88 | 15458977 | |
| MESH:D016893 | Carotid Stenosis | Plant Preparations | 4.86 | 15158307 | |
| MESH:D002386 | Cataract | Tretinoin | 2.20 | 17460283 | |
| MESH:D002471 | Cell Transformation, Neoplastic | 4-hydroxyestradiol-17 beta | 16.63 | 18226522 18566989 | |
| MESH:D002471 | Cell Transformation, Neoplastic | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | 16.63 | 20889678 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Cyclosporine | 16.63 | 12371664 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Diethylnitrosamine | 16.63 | 17174075 7505956 21159647 2727394 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Estradiol | 16.63 | 18566989 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Methylcholanthrene | 16.63 | 16192471 | |
| MESH:D002471 | Cell Transformation, Neoplastic | sodium arsenite | 16.63 | 19524636 20056578 | |
| MESH:D002547 | Cerebral Palsy | Toluene | 4.57 | 9294310 | |
| MESH:D018290 | Cervical Intraepithelial Neoplasia | Tretinoin | 3.31 | 16129372 | |
| MESH:D002637 | Chest Pain | Omeprazole | 3.82 | 15447763 | |
| MESH:D015362 | Child Nutrition Disorders | Vitamin A | 4.18 | 16153327 | |
| MESH:D018281 | Cholangiocarcinoma | 3,4,5,3',4'-pentachlorobiphenyl | 9.67 | 16628245 | |
| MESH:D018281 | Cholangiocarcinoma | Diethylnitrosamine | 9.67 | 19052882 | |
| MESH:D018281 | Cholangiocarcinoma | Tetrachlorodibenzodioxin | 9.67 | 16835633 | |
| MESH:D002764 | Cholecystitis | Indomethacin | 3.87 | 11181007 | |
| MESH:D002779 | Cholestasis | Cyclosporine | 10.69 | 19486331 | |
| MESH:D002779 | Cholestasis | Ethinyl Estradiol | 10.69 | 16919318 11677210 16105132 17333356 15861022 17110522 17681005 | |
| MESH:D002779 | Cholestasis | pirinixic acid | 10.69 | 19176532 | |
| MESH:D002779 | Cholestasis | Vitamin A | 10.69 | 16175620 | |
| MESH:D002822 | Choriocarcinoma | Tretinoin | 3.86 | 16461808 | |
| MESH:D002972 | Cleft Palate | Tetrachlorodibenzodioxin | 5.45 | 16354765 15340226 12621046 8697196 15668235 | |
| MESH:D002972 | Cleft Palate | Tretinoin | 5.45 | 9407595 | |
| MESH:D002972 | Cleft Palate | Vitamin A | 5.45 | 16054864 | |
| MESH:D003092 | Colitis | Curcumin | 12.88 | 16804969 16782535 18200517 | |
| MESH:D003092 | Colitis | resveratrol | 12.88 | 16474422 | |
| MESH:D003092 | Colitis | Rutin | 12.88 | 15652231 | |
| MESH:D003092 | Colitis | Tretinoin | 12.88 | 17035595 | |
| MESH:D003103 | Coloboma | Curcumin | 3.36 | 18809619 | |
| MESH:D003110 | Colonic Neoplasms | arsenite | 16.51 | 15037631 | |
| MESH:D003110 | Colonic Neoplasms | Curcumin | 16.51 | 19359593 16340194 | |
| MESH:D003110 | Colonic Neoplasms | decitabine | 16.51 | 17616700 | |
| MESH:D003110 | Colonic Neoplasms | Dexamethasone | 16.51 | 15824018 | |
| MESH:D003110 | Colonic Neoplasms | Genistein | 16.51 | 17182828 | |
| MESH:D003110 | Colonic Neoplasms | Indomethacin | 16.51 | 11260862 15625704 15637740 15963497 15936596 15786552 | |
| MESH:D003110 | Colonic Neoplasms | Quercetin | 16.51 | 11134977 19056647 19440933 17191121 15741050 17148506 16640504 | |
| MESH:D003110 | Colonic Neoplasms | resveratrol | 16.51 | 16338953 | |
| MESH:D003110 | Colonic Neoplasms | Sulindac | 16.51 | 12902858 12458338 | |
| MESH:D003110 | Colonic Neoplasms | Vitamin A | 16.51 | 17219422 16267017 | |
| MESH:D015179 | Colorectal Neoplasms | andrographolide | 8.87 | 19426720 | |
| MESH:D015179 | Colorectal Neoplasms | arsenic trioxide | 8.87 | 20501625 | |
| MESH:D015179 | Colorectal Neoplasms | Azacitidine | 8.87 | 19934284 | |
| MESH:D015179 | Colorectal Neoplasms | decitabine | 8.87 | 18981723 | |
| MESH:D015179 | Colorectal Neoplasms | Indomethacin | 8.87 | 17054584 12606626 11197048 18059344 | |
| MESH:D015179 | Colorectal Neoplasms | Polychlorinated Biphenyls | 8.87 | 15531428 | |
| MESH:D015179 | Colorectal Neoplasms | Quercetin | 8.87 | 18852136 18095365 | |
| MESH:D015179 | Colorectal Neoplasms | resveratrol | 8.87 | 16550006 | |
| MESH:D015179 | Colorectal Neoplasms | Sulindac | 8.87 | 11197048 10666051 18059344 11076880 | |
| MESH:D000013 | Congenital Abnormalities | DDT | 5.70 | 15095906 | |
| MESH:D000013 | Congenital Abnormalities | Tetrachlorodibenzodioxin | 5.70 | 14669216 17141729 | |
| MESH:D016510 | Corneal Neovascularization | Curcumin | 3.64 | 18497527 | |
| MESH:D003324 | Coronary Artery Disease | Plant Preparations | 3.35 | 15158307 | |
| MESH:D003327 | Coronary Disease | resveratrol | 2.79 | 16507316 | |
| MESH:D023903 | Coronary Restenosis | arsenic trioxide | 2.96 | 12609071 | |
| MESH:D018352 | Coronavirus Infections | Indomethacin | 4.42 | 17302372 | |
| MESH:D019465 | Craniofacial Abnormalities | 3,4,5,3',4'-pentachlorobiphenyl | 9.95 | 17686920 | |
| MESH:D019465 | Craniofacial Abnormalities | arsenic trioxide | 9.95 | 10525206 | |
| MESH:D019465 | Craniofacial Abnormalities | Benzene | 9.95 | 15643154 | |
| MESH:D019465 | Craniofacial Abnormalities | Dexamethasone | 9.95 | 17728286 | |
| MESH:D019465 | Craniofacial Abnormalities | sodium arsenate | 9.95 | 10525206 | |
| MESH:D019465 | Craniofacial Abnormalities | Tetrachlorodibenzodioxin | 9.95 | 15322242 20055451 10048152 | |
| MESH:D019465 | Craniofacial Abnormalities | Toluene | 9.95 | 9294310 | |
| MESH:D019465 | Craniofacial Abnormalities | Tretinoin | 9.95 | 9142499 9125849 9211117 10589399 9224671 14991402 8800419 9664655 16925845 17551590 | |
| MESH:D019465 | Craniofacial Abnormalities | Vitamin A | 9.95 | 10992263 | |
| MESH:D016638 | Critical Illness | Estrogens | 4.67 | 16670151 | |
| MESH:D003456 | Cryptorchidism | Dibutyl Phthalate | 7.70 | 16037377 | |
| MESH:D003456 | Cryptorchidism | Diethylstilbestrol | 7.70 | 16002989 12952375 | |
| MESH:D003550 | Cystic Fibrosis | Glutathione | 3.38 | 19747007 | |
| MESH:D003556 | Cystitis | Cyclophosphamide | 3.70 | 10700343 18710439 12388444 17010015 17979934 16651033 18372110 12161096 18295254 16614059 18483878 18093676 16989017 10498854 11948286 12913760 16413132 18433785 15643279 15276878 | |
| MESH:D003643 | Death | Toluene | 4.37 | 6431079 | |
| MESH:D016757 | Death, Sudden, Cardiac | arsenic trioxide | 2.89 | 15213294 | |
| MESH:D003704 | Dementia | Polychlorinated Biphenyls | 3.53 | 16140633 | |
| MESH:D003711 | Demyelinating Diseases | Tamoxifen | 3.11 | 19031437 | |
| MESH:D003872 | Dermatitis | Benzene | 3.52 | 15902427 | |
| MESH:D017449 | Dermatitis, Allergic Contact | cobaltous chloride | 3.68 | 15059100 16823706 11298694 | |
| MESH:D017449 | Dermatitis, Allergic Contact | Dexamethasone | 3.68 | 12438553 | |
| MESH:D003876 | Dermatitis, Atopic | Diethylhexyl Phthalate | 4.27 | 16882537 | |
| MESH:D003876 | Dermatitis, Atopic | pirinixic acid | 4.27 | 18249437 | |
| MESH:D002658 | Developmental Disabilities | 2,3',4,4',5-pentachlorobiphenyl | 4.47 | 19647017 | |
| MESH:D003921 | Diabetes Mellitus, Experimental | Cyclophosphamide | 7.68 | 15331540 11751995 10990075 | |
| MESH:D003921 | Diabetes Mellitus, Experimental | Quercetin | 7.68 | 19496084 | |
| MESH:D003921 | Diabetes Mellitus, Experimental | resveratrol | 7.68 | 16873680 | |
| MESH:D003922 | Diabetes Mellitus, Type 1 | Cyclophosphamide | 3.92 | 18772604 | |
| MESH:D003922 | Diabetes Mellitus, Type 1 | Vitamin A | 3.92 | 16506275 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Curcumin | 7.53 | 18403477 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | daidzein | 7.53 | 16647724 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Diethylnitrosamine | 7.53 | 20387270 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Genistein | 7.53 | 16647724 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Tetrachlorodibenzodioxin | 7.53 | 17107852 | |
| MESH:D003928 | Diabetic Nephropathies | Curcumin | 16.25 | 18204486 | |
| MESH:D003928 | Diabetic Nephropathies | Estradiol | 16.25 | 19279558 | |
| MESH:D003928 | Diabetic Nephropathies | Plant Extracts | 16.25 | 19706694 | |
| MESH:D003928 | Diabetic Nephropathies | resveratrol | 16.25 | 16286809 | |
| MESH:D003928 | Diabetic Nephropathies | Tamoxifen | 16.25 | 19279558 | |
| MESH:D003929 | Diabetic Neuropathies | Progesterone | 3.24 | 17187935 | |
| MESH:D003930 | Diabetic Retinopathy | Sulindac | 3.95 | 12861449 17621415 | |
| MESH:D003967 | Diarrhea | Dexamethasone | 6.65 | 7237001 | |
| MESH:D003967 | Diarrhea | Indomethacin | 6.65 | 7907874 7237001 | |
| MESH:D003967 | Diarrhea | vorinostat | 6.65 | 20479100 | |
| MESH:D056486 | Drug-Induced Liver Injury | allyl sulfide | 13.23 | 15950962 | |
| MESH:D056486 | Drug-Induced Liver Injury | Carbon Tetrachloride | 13.23 | 19336974 21278145 6623471 16227642 7120509 17522070 19085960 4309450 11566570 2869522 16177239 9327722 7440962 6884620 3732212 15027814 15998439 10092053 3786805 10915739 15968718 7179309 | |
| MESH:D056486 | Drug-Induced Liver Injury | Chlorodiphenyl (54% Chlorine) | 13.23 | 17851650 | |
| MESH:D056486 | Drug-Induced Liver Injury | Diethylnitrosamine | 13.23 | 19107877 | |
| MESH:D056486 | Drug-Induced Liver Injury | Drugs, Chinese Herbal | 13.23 | 15027814 | |
| MESH:D056486 | Drug-Induced Liver Injury | Ketoconazole | 13.23 | 18289764 | |
| MESH:D056486 | Drug-Induced Liver Injury | sodium arsenate | 13.23 | 18186108 | |
| MESH:D056486 | Drug-Induced Liver Injury | Tetrachlorodibenzodioxin | 13.23 | 20420201 | |
| MESH:D056486 | Drug-Induced Liver Injury | Trichloroethylene | 13.23 | 7120509 | |
| MESH:D004362 | Drug Toxicity | Gentamicins | 11.14 | 11033412 15033597 | |
| MESH:D004362 | Drug Toxicity | Plant Preparations | 11.14 | 11033412 | |
| MESH:D004362 | Drug Toxicity | Tetrachlorodibenzodioxin | 11.14 | 11462148 | |
| MESH:D004362 | Drug Toxicity | Zidovudine | 11.14 | 15040536 | |
| MESH:D015352 | Dry Eye Syndromes | Vitamin A | 4.52 | 16146918 | |
| MESH:D004374 | Ductus Arteriosus, Patent | Indomethacin | 3.87 | 18446180 16133044 16326151 12774134 18043480 17190690 | |
| MESH:D004381 | Duodenal Ulcer | Curcumin | 12.04 | 17351913 | |
| MESH:D004381 | Duodenal Ulcer | Indomethacin | 12.04 | 11991626 11595415 17151854 17202747 17045617 11595431 17329845 10671773 11535926 16699067 17351913 | |
| MESH:D004381 | Duodenal Ulcer | lansoprazole | 12.04 | 17151854 | |
| MESH:D004381 | Duodenal Ulcer | Omeprazole | 12.04 | 21218061 17151854 16613094 15991576 | |
| MESH:D050171 | Dyslipidemias | Dietary Fats | 2.43 | 18367378 | |
| MESH:D004417 | Dyspnea | DDT | 6.80 | 16487989 | |
| MESH:D004417 | Dyspnea | Dichlorodiphenyl Dichloroethylene | 6.80 | 16487989 | |
| MESH:C538011 | Eales disease | Vitamin A | 4.32 | 9068938 | |
| MESH:D004480 | Ectromelia | Vitamin A | 4.52 | 16054864 | |
| MESH:D004485 | Eczema | Dexamethasone | 3.24 | 12438553 | |
| MESH:D004487 | Edema | Arachidonic Acid | 21.56 | 16716910 9831321 11698051 9599246 15177302 7990266 | |
| MESH:D004487 | Edema | Dexamethasone | 21.56 | 19703484 | |
| MESH:D004487 | Edema | Indomethacin | 21.56 | 10653021 16100529 8985016 7907874 19703484 7990266 8273558 | |
| MESH:D004487 | Edema | Mustard Gas | 21.56 | 11428631 9260866 11428647 11402378 | |
| MESH:D004487 | Edema | pirinixic acid | 21.56 | 12083418 | |
| MESH:D004487 | Edema | Plant Extracts | 21.56 | 12787963 | |
| MESH:D004487 | Edema | resveratrol | 21.56 | 8985016 | |
| MESH:D004487 | Edema | Tetrachlorodibenzodioxin | 21.56 | 12711302 11000095 | |
| MESH:D004487 | Edema | Tetradecanoylphorbol Acetate | 21.56 | 16716910 9599246 15177302 8273558 11698051 7812673 8113982 | |
| MESH:D004489 | Edema, Cardiac | 3,4,5,3',4'-pentachlorobiphenyl | 13.69 | 17686920 | |
| MESH:D004489 | Edema, Cardiac | Tetrachlorodibenzodioxin | 13.69 | 16714409 15322242 18230668 | |
| MESH:D004489 | Edema, Cardiac | Tretinoin | 13.69 | 18230668 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Ethinyl Estradiol | 12.05 | 12538720 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Progesterone | 12.05 | 17692515 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | resveratrol | 12.05 | 17872969 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Tamoxifen | 12.05 | 19031437 | |
| MESH:D004701 | Endocrine Gland Neoplasms | decitabine | 9.74 | 19294695 | |
| MESH:D004701 | Endocrine Gland Neoplasms | trichostatin A | 9.74 | 19294695 | |
| MESH:D018159 | Endolymphatic Hydrops | Dimethyl Sulfoxide | 5.26 | 20641076 | |
| MESH:D004714 | Endometrial Hyperplasia | Diethylstilbestrol | 7.68 | 16402032 | |
| MESH:D004714 | Endometrial Hyperplasia | Genistein | 7.68 | 16402032 | |
| MESH:D016889 | Endometrial Neoplasms | 4-hydroxytamoxifen | 20.20 | 19148513 | |
| MESH:D016889 | Endometrial Neoplasms | daidzein | 20.20 | 11473722 | |
| MESH:D016889 | Endometrial Neoplasms | Diethylstilbestrol | 20.20 | 16804899 15700306 | |
| MESH:D016889 | Endometrial Neoplasms | Estradiol | 20.20 | 18566989 11473722 19148513 | |
| MESH:D016889 | Endometrial Neoplasms | Genistein | 20.20 | 11473722 | |
| MESH:D016889 | Endometrial Neoplasms | Tamoxifen | 20.20 | 20544844 19155303 17893378 16202921 | |
| MESH:D016889 | Endometrial Neoplasms | Tretinoin | 20.20 | 16569247 | |
| MESH:D004715 | Endometriosis | 2,3,4,7,8-pentachlorodibenzofuran | 20.92 | 9294722 | |
| MESH:D004715 | Endometriosis | Indomethacin | 20.92 | 15652904 | |
| MESH:D004715 | Endometriosis | Mifepristone | 20.92 | 16134523 | |
| MESH:D004715 | Endometriosis | Progesterone | 20.92 | 16134523 | |
| MESH:D004715 | Endometriosis | Sulindac | 20.92 | 15652904 | |
| MESH:D004715 | Endometriosis | Tetrachlorodibenzodioxin | 20.92 | 9294722 10568697 | |
| MESH:D004719 | Endomyocardial Fibrosis | Plant Extracts | 4.38 | 15268973 | |
| MESH:D019446 | Endotoxemia | Indomethacin | 3.25 | 18509659 | |
| MESH:D004751 | Enteritis | Indomethacin | 7.81 | 10567023 17763956 16328016 | |
| MESH:D004751 | Enteritis | lansoprazole | 7.81 | 16328016 | |
| MESH:D020345 | Enterocolitis, Necrotizing | Indomethacin | 8.22 | 17980183 | |
| MESH:D020345 | Enterocolitis, Necrotizing | resveratrol | 8.22 | 17923197 | |
| MESH:D004802 | Eosinophilia | Cyclophosphamide | 5.18 | 11006010 | |
| MESH:D004802 | Eosinophilia | Indomethacin | 5.18 | 11298111 | |
| MESH:D004827 | Epilepsy | Plant Extracts | 2.93 | 19700373 19439326 | |
| MESH:D007172 | Erectile Dysfunction | daidzein | 3.81 | 14972507 | |
| MESH:D004890 | Erythema | Mustard Gas | 3.88 | 9357497 | |
| MESH:D004931 | Esophageal Achalasia | Diethylnitrosamine | 3.82 | 16302075 | |
| MESH:D004938 | Esophageal Neoplasms | 3',4'-dimethoxyflavone | 17.42 | 16530937 | |
| MESH:D004938 | Esophageal Neoplasms | 5,7-dimethoxyflavone | 17.42 | 16530937 | |
| MESH:D004938 | Esophageal Neoplasms | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | 17.42 | 20426865 | |
| MESH:D004938 | Esophageal Neoplasms | arsenic trioxide | 17.42 | 12903497 | |
| MESH:D004938 | Esophageal Neoplasms | Benzo(a)pyrene | 17.42 | 16530937 | |
| MESH:D004938 | Esophageal Neoplasms | docetaxel | 17.42 | 16337965 | |
| MESH:D004938 | Esophageal Neoplasms | Indomethacin | 17.42 | 11005569 | |
| MESH:D004938 | Esophageal Neoplasms | Plant Preparations | 17.42 | 16510608 | |
| MESH:D004938 | Esophageal Neoplasms | Sulindac | 17.42 | 12235107 | |
| MESH:D005124 | Eye Abnormalities | Tetrachlorodibenzodioxin | 5.31 | 11564622 | |
| MESH:D005124 | Eye Abnormalities | Tretinoin | 5.31 | 9664655 16938888 | |
| MESH:D005221 | Fatigue | vorinostat | 4.32 | 20479100 | |
| MESH:D005234 | Fatty Liver | arsenic trioxide | 39.62 | 15073043 | |
| MESH:D005234 | Fatty Liver | arsenite | 39.62 | 18296743 | |
| MESH:D005234 | Fatty Liver | Carbon Tetrachloride | 39.62 | 15959796 16045604 12631006 16239168 12795759 17595544 61145 19224547 | |
| MESH:D005234 | Fatty Liver | Curcumin | 39.62 | 19297423 | |
| MESH:D005234 | Fatty Liver | Cyclosporine | 39.62 | 19224547 | |
| MESH:D005234 | Fatty Liver | Dietary Fats | 39.62 | 17967931 19551842 19004024 18296743 | |
| MESH:D005234 | Fatty Liver | Diethylnitrosamine | 39.62 | 21071580 20387270 | |
| MESH:D005234 | Fatty Liver | Ethinyl Estradiol | 39.62 | 15345470 | |
| MESH:D005234 | Fatty Liver | pirinixic acid | 39.62 | 20131406 19236843 | |
| MESH:D005234 | Fatty Liver | Plant Extracts | 39.62 | 15975614 | |
| MESH:D005234 | Fatty Liver | Tamoxifen | 39.62 | 19224547 14986274 | |
| MESH:D005234 | Fatty Liver | Zidovudine | 39.62 | 18299183 | |
| MESH:D052776 | Female Urogenital Diseases | Diethylstilbestrol | 5.04 | 15751030 16611131 16002989 16534752 16513791 | |
| MESH:D052776 | Female Urogenital Diseases | Tamoxifen | 5.04 | 16709447 | |
| MESH:D005313 | Fetal Death | Tetrachlorodibenzodioxin | 2.22 | 11858732 | |
| MESH:D005327 | Fetal Resorption | Vitamin A | 4.07 | 16054864 | |
| MESH:D005334 | Fever | Arachidonic Acid | 5.78 | 11852909 | |
| MESH:D005334 | Fever | Indomethacin | 5.78 | 11852909 10431976 17627676 | |
| MESH:D018221 | Fibromatosis, Abdominal | Sulindac | 8.73 | 14745880 | |
| MESH:D018221 | Fibromatosis, Abdominal | Tamoxifen | 8.73 | 14745880 | |
| MESH:D018222 | Fibromatosis, Aggressive | Sulindac | 7.43 | 19069698 | |
| MESH:D018222 | Fibromatosis, Aggressive | Tamoxifen | 7.43 | 19069698 | |
| MESH:D005354 | Fibrosarcoma | Indomethacin | 7.88 | 10962813 | |
| MESH:D005354 | Fibrosarcoma | Methylcholanthrene | 7.88 | 10962813 14633661 | |
| MESH:D005355 | Fibrosis | arsenite | 41.31 | 18296743 | |
| MESH:D005355 | Fibrosis | baicalein | 41.31 | 19474275 | |
| MESH:D005355 | Fibrosis | Carbon Tetrachloride | 41.31 | 18705752 | |
| MESH:D005355 | Fibrosis | Curcumin | 41.31 | 18705752 | |
| MESH:D005355 | Fibrosis | Cyclosporine | 41.31 | 12168785 12639820 | |
| MESH:D005355 | Fibrosis | Dietary Fats | 41.31 | 18296743 | |
| MESH:D005355 | Fibrosis | Emodin | 41.31 | 19474275 | |
| MESH:D005355 | Fibrosis | Indomethacin | 41.31 | 17994277 | |
| MESH:D005355 | Fibrosis | Quercetin | 41.31 | 19474275 | |
| MESH:D005355 | Fibrosis | Tetrachlorodibenzodioxin | 41.31 | 20067830 | |
| MESH:D005355 | Fibrosis | Tretinoin | 41.31 | 17994277 | |
| MESH:D005499 | Folliculitis | Indomethacin | 3.87 | 11298111 | |
| MESH:D005706 | Gallbladder Neoplasms | arsenic trioxide | 3.03 | 16904648 | |
| MESH:D005756 | Gastritis | Indomethacin | 3.46 | 15046732 | |
| MESH:D005764 | Gastroesophageal Reflux | Sulindac | 3.78 | 11910360 | |
| MESH:D005770 | Gastrointestinal Neoplasms | Curcumin | 3.44 | 18462866 | |
| MESH:D005833 | Genital Neoplasms, Female | Diethylstilbestrol | 8.59 | 16452187 | |
| MESH:D005833 | Genital Neoplasms, Female | sodium arsenite | 8.59 | 16452187 | |
| MESH:D005885 | Gingival Hyperplasia | Cyclosporine | 2.94 | 8708960 | |
| OMIM:137750 | GLAUCOMA 1, OPEN ANGLE, A | marker/mechanism | |||
| OMIM:231300 | GLAUCOMA 3, PRIMARY CONGENITAL, A | marker/mechanism | |||
| OMIM:137760 | GLAUCOMA, PRIMARY OPEN ANGLE | marker/mechanism | |||
| MESH:D005909 | Glioblastoma | baicalein | 29.91 | 19804834 | |
| MESH:D005909 | Glioblastoma | biochanin A | 29.91 | 16598420 | |
| MESH:D005909 | Glioblastoma | Curcumin | 29.91 | 17596214 | |
| MESH:D005909 | Glioblastoma | Genistein | 29.91 | 16598420 | |
| MESH:D005909 | Glioblastoma | Indomethacin | 29.91 | 12870263 | |
| MESH:D005909 | Glioblastoma | myricetin | 29.91 | 19804834 | |
| MESH:D005909 | Glioblastoma | Okadaic Acid | 29.91 | 17312396 | |
| MESH:D005909 | Glioblastoma | Quercetin | 29.91 | 19804834 | |
| MESH:D005909 | Glioblastoma | Tretinoin | 29.91 | 17312396 | |
| MESH:D005909 | Glioblastoma | trichostatin A | 29.91 | 18801729 | |
| MESH:D005910 | Glioma | Indomethacin | 3.87 | 16487511 18371953 | |
| MESH:D005910 | Glioma | Quercetin | 3.87 | 17643826 | |
| MESH:D018316 | Gliosarcoma | Cyclophosphamide | 4.23 | 11389073 | |
| MESH:D005911 | Gliosis | Paraquat | 3.87 | 11124998 | |
| MESH:D005923 | Glomerulosclerosis, Focal Segmental | Indomethacin | 3.19 | 11849393 | |
| MESH:D018149 | Glucose Intolerance | sodium arsenate | 3.87 | 19446573 | |
| MESH:D006058 | Gonadal Disorders | Tetrachlorodibenzodioxin | 3.29 | 10696789 | |
| MESH:D006073 | Gout | Indomethacin | 4.07 | 11248219 | |
| MESH:D006086 | Graft vs Host Disease | Cyclophosphamide | 3.78 | 11014644 16376943 15172196 | |
| MESH:D006258 | Head and Neck Neoplasms | Curcumin | 10.31 | 18829502 18462866 | |
| MESH:D006258 | Head and Neck Neoplasms | decitabine | 10.31 | 19215824 | |
| MESH:D006258 | Head and Neck Neoplasms | Indomethacin | 10.31 | 15482327 | |
| MESH:D006258 | Head and Neck Neoplasms | Tretinoin | 10.31 | 16096774 | |
| MESH:D034381 | Hearing Loss | Dimethyl Sulfoxide | 6.83 | 20641076 | |
| MESH:D034381 | Hearing Loss | Gentamicins | 6.83 | 17868369 15968427 19130971 18024279 | |
| MESH:D006317 | Hearing Loss, Noise-Induced | Tretinoin | 3.86 | 16084493 | |
| MESH:D006330 | Heart Defects, Congenital | 2,3,4,7,8-pentachlorodibenzofuran | 25.72 | 11294989 | |
| MESH:D006330 | Heart Defects, Congenital | 3,4,3',4'-tetrachlorobiphenyl | 25.72 | 11294989 | |
| MESH:D006330 | Heart Defects, Congenital | 3,4,5,3',4'-pentachlorobiphenyl | 25.72 | 20471113 17686920 | |
| MESH:D006330 | Heart Defects, Congenital | Benzo(a)pyrene | 25.72 | 20471113 | |
| MESH:D006330 | Heart Defects, Congenital | benzo(k)fluoranthene | 25.72 | 20471113 | |
| MESH:D006330 | Heart Defects, Congenital | polychlorodibenzo-4-dioxin | 25.72 | 11294989 | |
| MESH:D006330 | Heart Defects, Congenital | Tetrachlorodibenzodioxin | 25.72 | 11294989 10048152 | |
| MESH:D006330 | Heart Defects, Congenital | Tretinoin | 25.72 | 14991402 9664655 | |
| MESH:D006330 | Heart Defects, Congenital | Vitamin A | 25.72 | 10992263 16080930 | |
| MESH:D006331 | Heart Diseases | Grape Seed Proanthocyanidins | 5.46 | 12587719 | |
| MESH:D006331 | Heart Diseases | pifithrin | 5.46 | 14766674 | |
| MESH:D006333 | Heart Failure | pirinixic acid | 4.12 | 20558911 | |
| MESH:D006333 | Heart Failure | Plant Extracts | 4.12 | 18097624 | |
| MESH:D006390 | Hemangioendothelioma | 2-Acetylaminofluorene | 4.02 | 6705139 | |
| MESH:D006394 | Hemangiosarcoma | 2-Acetylaminofluorene | 3.26 | 6705139 | |
| MESH:D006402 | Hematologic Diseases | Benzene | 7.08 | 16183116 | |
| MESH:D006402 | Hematologic Diseases | Zidovudine | 7.08 | 12579204 | |
| MESH:D006457 | Hemoglobinuria, Paroxysmal | Cyclosporine | 3.14 | 15720958 | |
| MESH:D006467 | Hemophilia A | Cyclophosphamide | 4.03 | 11918545 | |
| MESH:D006470 | Hemorrhage | Tetrachlorodibenzodioxin | 2.16 | 11000095 | |
| MESH:D006501 | Hepatic Encephalopathy | Indomethacin | 3.39 | 15633222 | |
| MESH:D006504 | Hepatic Veno-Occlusive Disease | Cyclophosphamide | 4.24 | 14986274 | |
| MESH:D006505 | Hepatitis | Carbon Tetrachloride | 12.67 | 19110552 19900420 | |
| MESH:D006505 | Hepatitis | DDT | 12.67 | 16487989 | |
| MESH:D006505 | Hepatitis | Dichlorodiphenyl Dichloroethylene | 12.67 | 16487989 | |
| MESH:D006505 | Hepatitis | Drugs, Chinese Herbal | 12.67 | 18339527 | |
| MESH:D019698 | Hepatitis C, Chronic | Indomethacin | 3.46 | 15135802 | |
| MESH:D006525 | Hepatitis, Viral, Human | allyl sulfide | 5.03 | 15950962 | |
| MESH:D006529 | Hepatomegaly | 2-xylene | 10.80 | 7457028 7457013 | |
| MESH:D006529 | Hepatomegaly | DDT | 10.80 | 2387028 | |
| MESH:D006529 | Hepatomegaly | pirinixic acid | 10.80 | 16221962 18467677 19772884 19176532 | |
| MESH:D006529 | Hepatomegaly | Tetrachlorodibenzodioxin | 10.80 | 15340226 12621046 16120746 | |
| MESH:D015417 | Hereditary Sensory and Motor Neuropathy | Curcumin | 3.78 | 17701891 | |
| MESH:D006548 | Hernia, Diaphragmatic | Dexamethasone | 4.03 | 7520565 | |
| MESH:D006548 | Hernia, Diaphragmatic | Vitamin A | 4.03 | 16863852 16490937 16877224 16292552 17436238 15707848 | |
| MESH:D006558 | Herpes Genitalis | Estradiol | 3.73 | 15709030 | |
| MESH:D006561 | Herpes Simplex | Plant Extracts | 5.95 | 10715843 | |
| MESH:D006561 | Herpes Simplex | resveratrol | 5.95 | 16876885 | |
| MESH:D015658 | HIV Infections | Plant Extracts | 6.02 | 12878215 | |
| MESH:D015658 | HIV Infections | Vitamin A | 6.02 | 16960176 | |
| MESH:D015658 | HIV Infections | Zidovudine | 6.02 | 20032539 17358032 11698656 11141242 11363243 | |
| MESH:D006679 | HIV Seropositivity | Vitamin A | 4.32 | 17209195 | |
| MESH:D006689 | Hodgkin Disease | Cyclophosphamide | 4.01 | 17606976 16135485 | |
| MESH:D006689 | Hodgkin Disease | sodium arsenite | 4.01 | 12676792 | |
| MESH:D019584 | Hot Flashes | Estradiol | 6.09 | 17088409 | |
| MESH:D019584 | Hot Flashes | Plant Extracts | 6.09 | 17454163 16566672 14716179 | |
| MESH:D006869 | Hydronephrosis | Tetrachlorodibenzodioxin | 2.75 | 16959395 15340226 18606429 8697196 16354765 | |
| MESH:D006930 | Hyperalgesia | Indomethacin | 4.46 | 12727271 | |
| MESH:D006930 | Hyperalgesia | Tretinoin | 4.46 | 16870215 | |
| MESH:D034321 | Hyperamylasemia | Indomethacin | 4.42 | 17883296 | |
| MESH:D006932 | Hyperbilirubinemia | Carbon Tetrachloride | 3.25 | 16899240 | |
| MESH:D053565 | Hypercalciuria | Gentamicins | 4.43 | 17652376 | |
| MESH:D006937 | Hypercholesterolemia | Curcumin | 8.62 | 18704882 | |
| MESH:D006937 | Hypercholesterolemia | Dietary Fats | 8.62 | 21332399 | |
| MESH:D006937 | Hypercholesterolemia | resveratrol | 8.62 | 17188708 | |
| MESH:D006940 | Hyperemia | Indomethacin | 3.73 | 12524144 | |
| MESH:D017681 | Hypereosinophilic Syndrome | Tretinoin | 3.31 | 16778211 | |
| MESH:D006943 | Hyperglycemia | kaempferol | 9.15 | 18262572 | |
| MESH:D006943 | Hyperglycemia | pirinixic acid | 9.15 | 20558911 | |
| MESH:D006943 | Hyperglycemia | Quercetin | 9.15 | 11834736 18262572 | |
| MESH:D020138 | Hyperhomocysteinemia | Plant Extracts | 3.34 | 16484555 | |
| MESH:D006949 | Hyperlipidemias | Dietary Fats | 12.34 | 21332399 | |
| MESH:D006949 | Hyperlipidemias | Indomethacin | 12.34 | 17546600 | |
| MESH:D006949 | Hyperlipidemias | Plant Extracts | 12.34 | 15975614 15268973 | |
| MESH:D006949 | Hyperlipidemias | resveratrol | 12.34 | 16873680 | |
| MESH:D017495 | Hyperpigmentation | 1-phenylazo-2-naphthol | 5.96 | 1402006 | |
| MESH:D006965 | Hyperplasia | Diethylstilbestrol | 3.19 | 12960047 14722030 | |
| MESH:D006968 | Hypersensitivity, Delayed | indirubin | 4.65 | 11275354 | |
| MESH:D006973 | Hypertension | Benzene | 11.14 | 17940673 | |
| MESH:D006973 | Hypertension | Cyclosporine | 11.14 | 10903974 | |
| MESH:D006973 | Hypertension | daidzein | 11.14 | 17169123 | |
| MESH:D006973 | Hypertension | Dexamethasone | 11.14 | 17042910 | |
| MESH:D006973 | Hypertension | Quercetin | 11.14 | 18356687 | |
| MESH:D006973 | Hypertension | Tetrachlorodibenzodioxin | 11.14 | 18850075 18670907 | |
| MESH:D006975 | Hypertension, Portal | Carbon Tetrachloride | 2.84 | 15338365 | |
| MESH:D017379 | Hypertrophy, Left Ventricular | resveratrol | 3.15 | 17488730 | |
| MESH:D006986 | Hypervitaminosis A | Vitamin A | 4.87 | 16054864 | |
| MESH:D007021 | Hypospadias | Diethylstilbestrol | 7.10 | 16002989 | |
| MESH:D007021 | Hypospadias | Ethinyl Estradiol | 7.10 | 16945680 16569931 | |
| MESH:D007077 | Ileal Diseases | 1-Methyl-3-isobutylxanthine | 8.44 | 18306037 | |
| MESH:D007077 | Ileal Diseases | Indomethacin | 8.44 | 10574470 18306037 | |
| MESH:D007079 | Ileitis | Indomethacin | 4.07 | 10647630 16133968 10651667 | |
| MESH:D007154 | Immune System Diseases | Cyclophosphamide | 4.04 | 16076520 | |
| MESH:D007235 | Infant, Premature, Diseases | Indomethacin | 4.07 | 16133044 | |
| MESH:D020244 | Infarction, Middle Cerebral Artery | pifithrin | 12.35 | 19475672 | |
| MESH:D020244 | Infarction, Middle Cerebral Artery | Progesterone | 12.35 | 15869954 | |
| MESH:D020244 | Infarction, Middle Cerebral Artery | resveratrol | 12.35 | 17600658 | |
| MESH:D007246 | Infertility | Diethylstilbestrol | 3.13 | 15036965 | |
| MESH:D007247 | Infertility, Female | Dieldrin | 6.31 | 10630421 | |
| MESH:D007247 | Infertility, Female | Ethinyl Estradiol | 6.31 | 12013081 | |
| MESH:D007248 | Infertility, Male | 2,2',3',4,4',5-hexachlorobiphenyl | 27.23 | 12948891 | |
| MESH:D007248 | Infertility, Male | 2,4-Dichlorophenoxyacetic Acid | 27.23 | 12948887 | |
| MESH:D007248 | Infertility, Male | Cyclophosphamide | 27.23 | 7193160 16517039 | |
| MESH:D007248 | Infertility, Male | DDT | 27.23 | 17192596 17157474 | |
| MESH:D007248 | Infertility, Male | decitabine | 27.23 | 17581917 | |
| MESH:D007248 | Infertility, Male | Dichlorodiphenyl Dichloroethylene | 27.23 | 17192596 12948891 | |
| MESH:D007248 | Infertility, Male | Ethinyl Estradiol | 27.23 | 17937319 | |
| MESH:D007248 | Infertility, Male | fulvestrant | 27.23 | 11514358 | |
| MESH:D007248 | Infertility, Male | Paraquat | 27.23 | 4850670 | |
| MESH:D007248 | Infertility, Male | sodium arsenite | 27.23 | 15346721 12646999 | |
| MESH:D007249 | Inflammation | Arachidonic Acid | 36.80 | 17371808 15177302 9831321 | |
| MESH:D007249 | Inflammation | Curcumin | 36.80 | 16956363 18403477 17151092 | |
| MESH:D007249 | Inflammation | Dexamethasone | 36.80 | 8960868 11099482 | |
| MESH:D007249 | Inflammation | Dietary Fats | 36.80 | 20412841 | |
| MESH:D007249 | Inflammation | Diethylnitrosamine | 36.80 | 18785209 | |
| MESH:D007249 | Inflammation | ethylisopropylamiloride | 36.80 | 17237260 | |
| MESH:D007249 | Inflammation | Indomethacin | 36.80 | 7812673 3291741 12568917 | |
| MESH:D007249 | Inflammation | Mustard Gas | 36.80 | 9357497 16001271 8975870 11428647 17524151 11402378 11428620 11428631 9260866 | |
| MESH:D007249 | Inflammation | Plant Extracts | 36.80 | 15997105 16366677 19332304 12787963 | |
| MESH:D007249 | Inflammation | Progesterone | 36.80 | 15869954 | |
| MESH:D007249 | Inflammation | resveratrol | 36.80 | 16366677 | |
| MESH:D007249 | Inflammation | Sulindac | 36.80 | 3291741 | |
| MESH:D007249 | Inflammation | Tamoxifen | 36.80 | 19457130 | |
| MESH:D007249 | Inflammation | Tetrachlorodibenzodioxin | 36.80 | 12200463 12878042 | |
| MESH:D007249 | Inflammation | Tetradecanoylphorbol Acetate | 36.80 | 15177302 7562506 8273558 11698051 7812673 | |
| MESH:D007249 | Inflammation | Tobacco Smoke Pollution | 36.80 | 18590791 | |
| MESH:D015212 | Inflammatory Bowel Diseases | Curcumin | 4.61 | 18200517 18596194 | |
| MESH:D015212 | Inflammatory Bowel Diseases | Rutin | 4.61 | 15652231 | |
| MESH:D007251 | Influenza, Human | Quercetin | 6.93 | 16624496 | |
| MESH:D007251 | Influenza, Human | resveratrol | 6.93 | 16624496 | |
| MESH:D007333 | Insulin Resistance | bisphenol A | 9.61 | 16393666 | |
| MESH:D007333 | Insulin Resistance | Dietary Fats | 9.61 | 11836018 18457598 | |
| MESH:D007333 | Insulin Resistance | Estradiol | 9.61 | 16627594 16393666 | |
| MESH:D007333 | Insulin Resistance | pirinixic acid | 9.61 | 16306350 | |
| MESH:D007410 | Intestinal Diseases | Indomethacin | 5.78 | 10210152 11686837 15610444 11855677 18236018 11713966 17329856 15831440 17994277 | |
| MESH:D007410 | Intestinal Diseases | Tretinoin | 5.78 | 17994277 | |
| MESH:D007414 | Intestinal Neoplasms | Curcumin | 9.89 | 10783313 | |
| MESH:D007414 | Intestinal Neoplasms | Plant Extracts | 9.89 | 12351151 12584176 12628509 | |
| MESH:D007414 | Intestinal Neoplasms | Sulindac | 9.89 | 12584176 12663524 12351151 12628509 10223192 10213222 | |
| MESH:D007417 | Intestinal Polyps | Sulindac | 3.78 | 11245490 12394442 | |
| MESH:D019586 | Intracranial Hypertension | Indomethacin | 9.90 | 15241188 | |
| MESH:D019586 | Intracranial Hypertension | Vitamin A | 9.90 | 15955940 | |
| MESH:D007569 | Jaw Abnormalities | Tetrachlorodibenzodioxin | 6.01 | 16580747 | |
| MESH:D007569 | Jaw Abnormalities | Tretinoin | 6.01 | 15992940 17551590 | |
| MESH:D007579 | Jejunal Diseases | 1-Methyl-3-isobutylxanthine | 8.44 | 18306037 | |
| MESH:D007579 | Jejunal Diseases | Indomethacin | 8.44 | 10574470 18306037 16133968 | |
| MESH:D007627 | Keloid | Quercetin | 3.70 | 17086741 | |
| MESH:D007638 | Keratoconjunctivitis Sicca | Cyclosporine | 3.14 | 15604871 | |
| MESH:D007673 | Kidney Cortex Necrosis | Gentamicins | 4.43 | 18842672 | |
| MESH:D007674 | Kidney Diseases | Cadmium Chloride | 18.03 | 16962696 | |
| MESH:D007674 | Kidney Diseases | Cyclosporine | 18.03 | 8314463 10903974 18776723 | |
| MESH:D007674 | Kidney Diseases | Estradiol | 18.03 | 15618244 | |
| MESH:D007674 | Kidney Diseases | Gentamicins | 18.03 | 17934191 18289764 19349640 | |
| MESH:D007674 | Kidney Diseases | Grape Seed Proanthocyanidins | 18.03 | 12587719 | |
| MESH:D007674 | Kidney Diseases | Indomethacin | 18.03 | 17190690 | |
| MESH:D007674 | Kidney Diseases | Quercetin | 18.03 | 16962696 | |
| MESH:D007674 | Kidney Diseases | sodium arsenite | 18.03 | 20008137 | |
| MESH:D007676 | Kidney Failure, Chronic | Hydrogen Peroxide | 3.10 | 16518626 | |
| MESH:D007680 | Kidney Neoplasms | Cyclosporine | 15.09 | 12371664 | |
| MESH:D007680 | Kidney Neoplasms | Diethylstilbestrol | 15.09 | 15003126 14681315 16762066 | |
| MESH:D007680 | Kidney Neoplasms | Estradiol | 15.09 | 15610895 | |
| MESH:D007680 | Kidney Neoplasms | Estrone | 15.09 | 15610895 | |
| MESH:D007680 | Kidney Neoplasms | Tamoxifen | 15.09 | 18625569 | |
| MESH:D007680 | Kidney Neoplasms | Zidovudine | 15.09 | 12579204 | |
| MESH:D007683 | Kidney Tubular Necrosis, Acute | Calcium | 7.83 | 16316344 | |
| MESH:D007683 | Kidney Tubular Necrosis, Acute | Gentamicins | 7.83 | 11231351 | |
| MESH:D007859 | Learning Disorders | DDT | 5.98 | 7589230 | |
| MESH:D007859 | Learning Disorders | Diethylstilbestrol | 5.98 | 17184923 | |
| MESH:D007889 | Leiomyoma | Curcumin | 3.37 | 18555241 | |
| MESH:D016773 | Leishmaniasis, Cutaneous | Gentamicins | 10.94 | 10219319 | |
| MESH:D016773 | Leishmaniasis, Cutaneous | Indomethacin | 10.94 | 10320625 12228301 11703811 | |
| MESH:D016773 | Leishmaniasis, Cutaneous | Ketoconazole | 10.94 | 2166429 1311351 19744259 8889330 | |
| MESH:D016773 | Leishmaniasis, Cutaneous | Omeprazole | 10.94 | 19248655 | |
| MESH:D007898 | Leishmaniasis, Visceral | Ketoconazole | 3.53 | 11332679 | |
| MESH:D007938 | Leukemia | arsenic trioxide | 27.19 | 15070760 | |
| MESH:D007938 | Leukemia | Azacitidine | 27.19 | 19148494 | |
| MESH:D007938 | Leukemia | Benzene | 27.19 | 14694614 18335105 15935818 17119257 | |
| MESH:D007938 | Leukemia | Curcumin | 27.19 | 18462866 | |
| MESH:D007938 | Leukemia | Cyclophosphamide | 27.19 | 10602166 | |
| MESH:D007938 | Leukemia | decitabine | 27.19 | 18980019 19235587 | |
| MESH:D007938 | Leukemia | Genistein | 27.19 | 17468513 18980019 | |
| MESH:D007938 | Leukemia | kaempferol | 27.19 | 17468513 | |
| MESH:D007938 | Leukemia | Quercetin | 27.19 | 17468513 | |
| MESH:D007938 | Leukemia | Tretinoin | 27.19 | 17143497 | |
| MESH:D015451 | Leukemia, Lymphocytic, Chronic, B-Cell | Cyclophosphamide | 4.47 | 18587576 18172266 17296974 17658394 17008537 17802794 | |
| MESH:D015451 | Leukemia, Lymphocytic, Chronic, B-Cell | Drugs, Chinese Herbal | 4.47 | 15802533 | |
| MESH:D015459 | Leukemia-Lymphoma, Adult T-Cell | arsenic trioxide | 13.64 | 17077332 12560223 | |
| MESH:D015459 | Leukemia-Lymphoma, Adult T-Cell | Curcumin | 13.64 | 16106398 | |
| MESH:D015459 | Leukemia-Lymphoma, Adult T-Cell | Emodin | 13.64 | 17077332 | |
| MESH:D015459 | Leukemia-Lymphoma, Adult T-Cell | Zidovudine | 13.64 | 20370541 | |
| MESH:D007948 | Leukemia, Monocytic, Acute | arsenic trioxide | 7.51 | 16972261 | |
| MESH:D007948 | Leukemia, Monocytic, Acute | PD 98059 | 7.51 | 16972261 | |
| MESH:D015464 | Leukemia, Myelogenous, Chronic, BCR-ABL Positive | arsenic trioxide | 8.07 | 14633726 | |
| MESH:D015464 | Leukemia, Myelogenous, Chronic, BCR-ABL Positive | Cyclophosphamide | 8.07 | 10373061 | |
| MESH:D015464 | Leukemia, Myelogenous, Chronic, BCR-ABL Positive | Indomethacin | 8.07 | 10785260 16572323 15631656 | |
| MESH:D007951 | Leukemia, Myeloid | arsenic trioxide | 17.61 | 19077051 | |
| MESH:D007951 | Leukemia, Myeloid | Azacitidine | 17.61 | 19077051 | |
| MESH:D007951 | Leukemia, Myeloid | Benzene | 17.61 | 17506065 | |
| MESH:D007951 | Leukemia, Myeloid | decitabine | 17.61 | 17236224 19117987 18454857 | |
| MESH:D007951 | Leukemia, Myeloid | Tretinoin | 17.61 | 16482212 16932348 19285840 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | arsenic trioxide | 10.66 | 16467208 17050201 16968895 20471514 19850784 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | Azacitidine | 10.66 | 18720364 17596541 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | Benzene | 10.66 | 19478238 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | decitabine | 10.66 | 17679729 18460780 19387464 18704418 19010910 18206229 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | Indomethacin | 10.66 | 18360721 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | Tretinoin | 10.66 | 16294345 17596541 19850784 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | trichostatin A | 10.66 | 18206229 | |
| MESH:D015477 | Leukemia, Myelomonocytic, Chronic | decitabine | 4.16 | 18055864 | |
| MESH:D054429 | Leukemia, Myelomonocytic, Juvenile | Azacitidine | 3.98 | 19299654 | |
| MESH:D015473 | Leukemia, Promyelocytic, Acute | arsenic trioxide | 7.09 | 16966277 15213294 16331271 16891316 17869043 17107899 15748426 16823087 15622746 12712474 19225113 19075265 16330433 17712046 15336539 19642359 11161223 17649720 12679006 16112521 9834237 12018890 17217047 19035177 11468182 | |
| MESH:D015473 | Leukemia, Promyelocytic, Acute | resveratrol | 7.09 | 16087638 | |
| MESH:D015473 | Leukemia, Promyelocytic, Acute | Tretinoin | 7.09 | 16331271 16935935 9834237 16140955 17368321 17217047 16766008 17294898 15748426 17301526 19642359 19225113 19075265 17506722 17712046 16823087 16891316 12679006 17107899 17361223 17649720 19029980 16788101 17339181 19035177 | |
| MESH:D015458 | Leukemia, T-Cell | arsenic trioxide | 7.63 | 16882451 | |
| MESH:D015458 | Leukemia, T-Cell | Curcumin | 7.63 | 16106398 | |
| MESH:D007964 | Leukocytosis | Indomethacin | 4.07 | 16537180 | |
| MESH:D007969 | Leukomalacia, Periventricular | Indomethacin | 4.42 | 17980183 | |
| MESH:D007970 | Leukopenia | Cyclophosphamide | 3.70 | 11830472 10052129 | |
| MESH:D017880 | Limb Deformities, Congenital | Dichlorodiphenyl Dichloroethylene | 7.97 | 12745335 | |
| MESH:D017880 | Limb Deformities, Congenital | Tretinoin | 7.97 | 9224671 | |
| MESH:D017880 | Limb Deformities, Congenital | Vitamin A | 7.97 | 16054864 | |
| MESH:D008064 | Lipidoses | Ketoconazole | 4.90 | 17567588 | |
| MESH:D008064 | Lipidoses | Tamoxifen | 4.90 | 15342952 17567588 | |
| MESH:D008101 | Liver Abscess, Amebic | Indomethacin | 4.42 | 11479899 | |
| MESH:D008103 | Liver Cirrhosis | arsenite | 17.66 | 18296743 | |
| MESH:D008103 | Liver Cirrhosis | Carbon Tetrachloride | 17.66 | 16239168 16943688 17334410 11408273 21278145 17157831 16221502 11903743 17174718 | |
| MESH:D008103 | Liver Cirrhosis | Dietary Fats | 17.66 | 18296743 | |
| MESH:D008103 | Liver Cirrhosis | Diethylnitrosamine | 17.66 | 18522880 19638242 18665156 18407596 20032147 | |
| MESH:D008103 | Liver Cirrhosis | Drugs, Chinese Herbal | 17.66 | 17163593 | |
| MESH:D008103 | Liver Cirrhosis | Plant Extracts | 17.66 | 17157831 | |
| MESH:D008103 | Liver Cirrhosis | Vitamin A | 17.66 | 16256175 | |
| MESH:D008105 | Liver Cirrhosis, Biliary | Sulindac | 3.27 | 12468960 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Carbon Tetrachloride | 28.45 | 14716496 15650968 15370692 12958196 12667390 15996030 18418968 14724832 18376398 18263696 17869086 12586293 17708605 15959796 13678700 10355542 17761835 12741479 15876570 11481614 16248980 17976157 15338365 15052691 12632514 20821823 17805973 15123356 18251166 16011737 18006644 18317297 18205269 17766677 18429990 16116963 16136751 18339082 16027843 18187930 14620537 15362042 17714472 17565644 12546737 16192424 16015684 12632512 12389079 17631135 18210741 18279442 17823541 17721639 12666154 15893842 17698563 18277467 18156304 12609069 18412020 18705752 15730626 12649538 17525996 17944888 14512876 18166357 18472332 15931870 12898905 16033810 12445418 18420326 17481882 15057751 15925388 18472094 15818738 16638106 15673190 18395095 18395914 14748882 12445421 14716833 17557913 16097048 17640975 18481824 18054572 17900296 17922224 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Curcumin | 28.45 | 17355460 18705752 18006644 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Dexamethasone | 28.45 | 16718785 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Dimethyl Sulfoxide | 28.45 | 11682029 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Drugs, Chinese Herbal | 28.45 | 15763062 15641146 15849816 15754396 17348192 15383259 17881167 16610055 18237412 12632512 15864749 15818738 17629604 18371158 17666798 15744066 17036385 18606216 15339415 18567088 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Emodin | 28.45 | 15288473 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Estradiol | 28.45 | 14716833 14659978 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Genistein | 28.45 | 17823541 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Indomethacin | 28.45 | 18194892 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Melatonin | 28.45 | 15298665 16703270 15925388 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | oltipraz | 28.45 | 16544323 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | pirinixic acid | 28.45 | 15474484 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Plant Extracts | 28.45 | 15479170 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Plant Preparations | 28.45 | 17724770 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Quercetin | 28.45 | 12741479 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Tamoxifen | 28.45 | 18564211 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Tetrachlorodibenzodioxin | 28.45 | 12878042 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Tretinoin | 28.45 | 18397230 16248980 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Vitamin A | 28.45 | 16248980 | |
| MESH:D008107 | Liver Diseases | Carbon Tetrachloride | 17.45 | 16964402 15720792 15830285 16246199 17285989 | |
| MESH:D008107 | Liver Diseases | Curcumin | 17.45 | 16956363 | |
| MESH:D008107 | Liver Diseases | DDT | 17.45 | 15729006 | |
| MESH:D008107 | Liver Diseases | Diethylnitrosamine | 17.45 | 17034775 | |
| MESH:D008107 | Liver Diseases | Drugs, Chinese Herbal | 17.45 | 17207593 | |
| MESH:D008107 | Liver Diseases | Grape Seed Proanthocyanidins | 17.45 | 12587719 | |
| MESH:D008107 | Liver Diseases | Lindane | 17.45 | 1715830 | |
| MESH:D008107 | Liver Diseases | Plant Extracts | 17.45 | 17034775 | |
| MESH:D008107 | Liver Diseases | Sulindac | 17.45 | 14986274 16867024 | |
| MESH:D008107 | Liver Diseases | Vitamin A | 17.45 | 16175620 | |
| MESH:D008108 | Liver Diseases, Alcoholic | Vitamin A | 3.91 | 16762690 | |
| MESH:D017093 | Liver Failure | Carbon Tetrachloride | 2.91 | 15123358 | |
| MESH:D017114 | Liver Failure, Acute | Carbon Tetrachloride | 2.54 | 14706259 16899240 | |
| MESH:D008113 | Liver Neoplasms | 2,4,5,2',4',5'-hexachlorobiphenyl | 59.69 | 18644402 16835634 | |
| MESH:D008113 | Liver Neoplasms | 2-Acetylaminofluorene | 59.69 | 14678523 10737359 11376686 16273603 18001218 10672840 | |
| MESH:D008113 | Liver Neoplasms | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 59.69 | 15890375 | |
| MESH:D008113 | Liver Neoplasms | 9,10-Dimethyl-1,2-benzanthracene | 59.69 | 9643874 | |
| MESH:D008113 | Liver Neoplasms | 9-(4'-aminophenyl)-9H-pyrido(3,4-b)indole | 59.69 | 12970073 | |
| MESH:D008113 | Liver Neoplasms | Aflatoxin B1 | 59.69 | 2125692 9163691 15890375 18177683 | |
| MESH:D008113 | Liver Neoplasms | arsenic trioxide | 59.69 | 14682389 | |
| MESH:D008113 | Liver Neoplasms | Benzo(a)pyrene | 59.69 | 21137059 20195826 | |
| MESH:D008113 | Liver Neoplasms | beta-Naphthoflavone | 59.69 | 19389873 21295105 | |
| MESH:D008113 | Liver Neoplasms | Carbon Tetrachloride | 59.69 | 19294768 | |
| MESH:D008113 | Liver Neoplasms | DDT | 59.69 | 15975961 11948501 | |
| MESH:D008113 | Liver Neoplasms | Dieldrin | 59.69 | 8742319 9539021 | |
| MESH:D008113 | Liver Neoplasms | Diethylhexyl Phthalate | 59.69 | 11940454 | |
| MESH:D008113 | Liver Neoplasms | Diethylnitrosamine | 59.69 | 20118626 2862719 19690152 15885732 19551842 20583210 19812893 9163691 18754104 19996281 20101389 19833225 18978307 19255062 20501860 19256749 19090486 19642983 18977376 20405173 2422723 21167192 15175105 21071580 19850985 10737359 20452335 20492335 18644402 19073162 18648771 12771043 20434301 19499222 19294768 21278145 19254457 16942905 19427195 21047994 19426721 12112319 19638242 20137499 | |
| MESH:D008113 | Liver Neoplasms | Diethylstilbestrol | 59.69 | 16712894 15890375 | |
| MESH:D008113 | Liver Neoplasms | Drugs, Chinese Herbal | 59.69 | 18339527 | |
| MESH:D008113 | Liver Neoplasms | pirinixic acid | 59.69 | 16377806 20007298 15890375 | |
| MESH:D008113 | Liver Neoplasms | Plant Extracts | 59.69 | 19168119 | |
| MESH:D008113 | Liver Neoplasms | Quercetin | 59.69 | 18980244 | |
| MESH:D008113 | Liver Neoplasms | resveratrol | 59.69 | 19073162 20405173 19812893 19321006 | |
| MESH:D008113 | Liver Neoplasms | sodium arsenite | 59.69 | 15276417 16712894 | |
| MESH:D008113 | Liver Neoplasms | Tamoxifen | 59.69 | 16684651 | |
| MESH:D008113 | Liver Neoplasms | Tetrachlorodibenzodioxin | 59.69 | 16984957 | |
| MESH:D008114 | Liver Neoplasms, Experimental | 1-phenylazo-2-naphthol | 43.57 | 2563599 | |
| MESH:D008114 | Liver Neoplasms, Experimental | 2-Acetylaminofluorene | 43.57 | 1399818 534488 6150874 | |
| MESH:D008114 | Liver Neoplasms, Experimental | 9,10-Dimethyl-1,2-benzanthracene | 43.57 | 1399818 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Aflatoxin B1 | 43.57 | 8603461 | |
| MESH:D008114 | Liver Neoplasms, Experimental | arsenic trioxide | 43.57 | 20377131 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Benzene | 43.57 | 12562636 | |
| MESH:D008114 | Liver Neoplasms, Experimental | beta-Naphthoflavone | 43.57 | 18164116 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Carbon Tetrachloride | 43.57 | 12014681 15583823 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Diethylnitrosamine | 43.57 | 9362446 18775883 18093689 17854601 18282651 19009564 18253720 18079962 19519916 18544905 19004024 17174075 18164116 19539802 18308698 16267830 17942915 21159647 16842330 2563599 19126423 3124819 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Hexachlorobenzene | 43.57 | 1423854 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Methylcholanthrene | 43.57 | 1399818 598648 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Polychlorinated Biphenyls | 43.57 | 1423854 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Quercetin | 43.57 | 19519916 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Tetrachlorodibenzodioxin | 43.57 | 12151625 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Trichloroethylene | 43.57 | 7955063 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Vitamin A | 43.57 | 17113696 | |
| MESH:D008133 | Long QT Syndrome | arsenic trioxide | 2.32 | 15213294 | |
| MESH:D008171 | Lung Diseases | Grape Seed Proanthocyanidins | 12.66 | 12587719 | |
| MESH:D008171 | Lung Diseases | Mustard Gas | 12.66 | 18161513 18702808 | |
| MESH:D008171 | Lung Diseases | Ozone | 12.66 | 8266340 19066396 | |
| MESH:D008171 | Lung Diseases | sodium arsenite | 12.66 | 19095001 | |
| MESH:D008171 | Lung Diseases | Vitamin A | 12.66 | 16863852 | |
| MESH:D017563 | Lung Diseases, Interstitial | Benzene | 3.52 | 14698565 | |
| MESH:D055370 | Lung Injury | Ozone | 2.65 | 20417186 | |
| MESH:D008175 | Lung Neoplasms | marker/mechanism | 11376689 | ||
| MESH:D008175 | Lung Neoplasms | 2-Acetylaminofluorene | 62.50 | 11376686 | |
| MESH:D008175 | Lung Neoplasms | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 62.50 | 14755239 12438228 18508827 9255578 15893417 17139156 19931552 18813816 15172992 16401635 16061637 | |
| MESH:D008175 | Lung Neoplasms | 9,10-Dimethyl-1,2-benzanthracene | 62.50 | 11376689 | |
| MESH:D008175 | Lung Neoplasms | Aflatoxin B1 | 62.50 | 14755239 | |
| MESH:D008175 | Lung Neoplasms | arsenic trioxide | 62.50 | 19825857 11798837 | |
| MESH:D008175 | Lung Neoplasms | arsenite | 62.50 | 16809336 | |
| MESH:D008175 | Lung Neoplasms | Azacitidine | 62.50 | 21224363 | |
| MESH:D008175 | Lung Neoplasms | Benzene | 62.50 | 12562636 | |
| MESH:D008175 | Lung Neoplasms | Benzo(a)pyrene | 62.50 | 6695378 20464547 18816296 17053015 18569708 18520028 20135361 20869020 20064080 | |
| MESH:D008175 | Lung Neoplasms | bexarotene | 62.50 | 17849452 | |
| MESH:D008175 | Lung Neoplasms | Curcumin | 62.50 | 16243823 19359593 18462866 | |
| MESH:D008175 | Lung Neoplasms | Dexamethasone | 62.50 | 15824018 11195469 | |
| MESH:D008175 | Lung Neoplasms | Diethylnitrosamine | 62.50 | 6695378 20970405 21163286 20512841 | |
| MESH:D008175 | Lung Neoplasms | Drugs, Chinese Herbal | 62.50 | 18339527 | |
| MESH:D008175 | Lung Neoplasms | Indomethacin | 62.50 | 11497255 11053908 16537180 | |
| MESH:D008175 | Lung Neoplasms | Melatonin | 62.50 | 17195641 | |
| MESH:D008175 | Lung Neoplasms | Methylcholanthrene | 62.50 | 9230183 11893704 15390079 20512841 16337739 10545420 7750092 21163286 20970405 1399818 16271038 6695378 17909032 | |
| MESH:D008175 | Lung Neoplasms | Methylene Chloride | 62.50 | 15172992 | |
| MESH:D008175 | Lung Neoplasms | Mustard Gas | 62.50 | 3148597 8781369 | |
| MESH:D008175 | Lung Neoplasms | Ozone | 62.50 | 8597069 7614698 | |
| MESH:D008175 | Lung Neoplasms | Plant Extracts | 62.50 | 20869020 | |
| MESH:D008175 | Lung Neoplasms | Polycyclic Hydrocarbons, Aromatic | 62.50 | 10814675 | |
| MESH:D008175 | Lung Neoplasms | Quercetin | 62.50 | 16280456 | |
| MESH:D008175 | Lung Neoplasms | sodium arsenite | 62.50 | 17077188 16712894 15276417 19931552 17306315 | |
| MESH:D008175 | Lung Neoplasms | Soot | 62.50 | 9255578 | |
| MESH:D008175 | Lung Neoplasms | Sulindac | 62.50 | 15713900 19359593 | |
| MESH:D008175 | Lung Neoplasms | Tamoxifen | 62.50 | 18625569 | |
| MESH:D008175 | Lung Neoplasms | Tetrachlorodibenzodioxin | 62.50 | 19555203 11884234 | |
| MESH:D008175 | Lung Neoplasms | Tetradecanoylphorbol Acetate | 62.50 | 11807781 | |
| MESH:D008175 | Lung Neoplasms | Tobacco Smoke Pollution | 62.50 | 16288123 3440675 11091918 12111688 | |
| MESH:D008175 | Lung Neoplasms | Vehicle Emissions | 62.50 | 9255578 | |
| MESH:D008175 | Lung Neoplasms | Zidovudine | 62.50 | 18800350 | |
| MESH:D008180 | Lupus Erythematosus, Systemic | Melatonin | 3.39 | 16373423 | |
| MESH:D008181 | Lupus Nephritis | Diethylstilbestrol | 3.87 | 15166399 | |
| MESH:D008223 | Lymphoma | 9,10-Dimethyl-1,2-benzanthracene | 16.07 | 11376689 | |
| MESH:D008223 | Lymphoma | Benzene | 16.07 | 17584886 17119257 | |
| MESH:D008223 | Lymphoma | Curcumin | 16.07 | 18462866 | |
| MESH:D008223 | Lymphoma | Cyclophosphamide | 16.07 | 12854902 | |
| MESH:D008223 | Lymphoma | decitabine | 16.07 | 19470736 | |
| MESH:D008223 | Lymphoma | Diethylstilbestrol | 16.07 | 15700306 | |
| MESH:D016393 | Lymphoma, B-Cell | Cyclophosphamide | 6.49 | 16675587 | |
| MESH:D016393 | Lymphoma, B-Cell | resveratrol | 6.49 | 17088997 | |
| MESH:D008228 | Lymphoma, Non-Hodgkin | 2,4-Dichlorophenoxyacetic Acid | 8.43 | 16132792 | |
| MESH:D008228 | Lymphoma, Non-Hodgkin | Cyclophosphamide | 8.43 | 11911406 | |
| MESH:D008228 | Lymphoma, Non-Hodgkin | resveratrol | 8.43 | 14749477 | |
| MESH:D016399 | Lymphoma, T-Cell | Curcumin | 3.44 | 16173963 | |
| MESH:D016410 | Lymphoma, T-Cell, Cutaneous | bexarotene | 8.59 | 11161223 | |
| MESH:D016410 | Lymphoma, T-Cell, Cutaneous | vorinostat | 8.59 | 20479100 | |
| MESH:D052801 | Male Urogenital Diseases | Diethylstilbestrol | 4.22 | 16002989 | |
| MESH:D015674 | Mammary Neoplasms, Animal | Benzene | 9.56 | 12562636 | |
| MESH:D015674 | Mammary Neoplasms, Animal | resveratrol | 9.56 | 15688416 | |
| MESH:D015674 | Mammary Neoplasms, Animal | Tamoxifen | 9.56 | 19428831 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | 2,4-diaminotoluene | 29.41 | 11921183 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | 9,10-Dimethyl-1,2-benzanthracene | 29.41 | 18840765 12844480 10697514 8985016 11807958 16153821 16082771 1500032 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Benzene | 29.41 | 11921183 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | bexarotene | 29.41 | 19196723 15591091 19196722 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Drugs, Chinese Herbal | 29.41 | 14758024 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Estradiol | 29.41 | 11807958 17203775 11408345 16891317 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | fluasterone | 29.41 | 16457693 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Genistein | 29.41 | 12929590 14578162 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Progesterone | 29.41 | 11408345 17203775 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | resveratrol | 29.41 | 11606380 8985016 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Tamoxifen | 29.41 | 16827153 11731420 19196723 14580682 19196722 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Tetradecanoylphorbol Acetate | 29.41 | 8985016 | |
| MESH:D020149 | Manganese Poisoning | Estradiol | 8.36 | 19453300 | |
| MESH:D020149 | Manganese Poisoning | Tamoxifen | 8.36 | 19453300 | |
| MESH:D008527 | Medulloblastoma | Tretinoin | 2.08 | 17453147 | |
| MESH:D008545 | Melanoma | marker/mechanism | 17145863 | ||
| MESH:D008545 | Melanoma | Curcumin | 14.26 | 17885582 18462866 | |
| MESH:D008545 | Melanoma | decitabine | 14.26 | 16505122 17785578 | |
| MESH:D008545 | Melanoma | docetaxel | 14.26 | 12417787 | |
| MESH:D008545 | Melanoma | resveratrol | 14.26 | 17992120 | |
| MESH:D008545 | Melanoma | sodium arsenite | 14.26 | 19082730 16487513 | |
| MESH:D008545 | Melanoma | Sulindac | 14.26 | 16642371 | |
| MESH:D008545 | Melanoma | Tamoxifen | 14.26 | 12393984 19393235 | |
| MESH:D008545 | Melanoma | Tretinoin | 14.26 | 16752155 | |
| MESH:D008545 | Melanoma | trichostatin A | 14.26 | 16505122 | |
| MESH:D008545 | Melanoma | Vitamin K 3 | 14.26 | 19082730 | |
| MESH:D018328 | Melanoma, Amelanotic | Tamoxifen | 2.91 | 15990972 | |
| MESH:D008546 | Melanoma, Experimental | Cyclophosphamide | 3.56 | 16388313 | |
| MESH:D008569 | Memory Disorders | Curcumin | 2.95 | 17263510 | |
| MESH:D008591 | Meningomyelocele | Tretinoin | 3.17 | 16940565 | |
| MESH:D008607 | Mental Retardation | Toluene | 3.04 | 9294310 | |
| MESH:D008659 | Metabolic Diseases | resveratrol | 3.20 | 17112576 | |
| MESH:D008664 | Metal Metabolism, Inborn Errors | Cyclosporine | 3.49 | 16801185 | |
| MESH:D008679 | Metaplasia | Ozone | 3.81 | 10496685 | |
| MESH:D008708 | Methemoglobinemia | Primaquine | 4.49 | 3537620 | |
| MESH:D048629 | Micronuclei, Chromosome-Defective | Zidovudine | 4.54 | 17358032 | |
| MESH:D008881 | Migraine Disorders | Indomethacin | 2.70 | 11903285 | |
| MESH:D020326 | Migraine without Aura | Cyclic AMP | 3.94 | 11304026 | |
| MESH:D009006 | Monosomy | Azacitidine | 4.78 | 19299654 | |
| MESH:D019957 | Motor Skills Disorders | Toluene | 4.03 | 9294310 | |
| MESH:D009062 | Mouth Neoplasms | Benzo(a)pyrene | 11.86 | 16381670 | |
| MESH:D009062 | Mouth Neoplasms | Indomethacin | 11.86 | 12636206 | |
| MESH:D009062 | Mouth Neoplasms | Plant Preparations | 11.86 | 17418620 | |
| MESH:D009062 | Mouth Neoplasms | Tobacco Smoke Pollution | 11.86 | 15006635 | |
| MESH:D009101 | Multiple Myeloma | arsenic trioxide | 25.89 | 19549372 15949261 11468182 14977855 19417148 | |
| MESH:D009101 | Multiple Myeloma | Azacitidine | 25.89 | 18443271 19549372 | |
| MESH:D009101 | Multiple Myeloma | Benzene | 25.89 | 17119195 | |
| MESH:D009101 | Multiple Myeloma | Curcumin | 25.89 | 19372569 | |
| MESH:D009101 | Multiple Myeloma | decitabine | 25.89 | 18172295 | |
| MESH:D009101 | Multiple Myeloma | Dexamethasone | 25.89 | 16118317 15744524 15867202 | |
| MESH:D009101 | Multiple Myeloma | resveratrol | 25.89 | 17049120 16490592 14749477 16267019 17935668 17164350 | |
| MESH:D009101 | Multiple Myeloma | trichostatin A | 25.89 | 18172295 | |
| MESH:D009101 | Multiple Myeloma | Vitamin A | 25.89 | 16374440 | |
| MESH:D009134 | Muscular Atrophy, Spinal | Curcumin | 8.19 | 17962980 | |
| MESH:D009134 | Muscular Atrophy, Spinal | resveratrol | 8.19 | 17962980 | |
| MESH:D009135 | Muscular Diseases | pirinixic acid | 2.27 | 16239165 | |
| MESH:D009137 | Muscular Dystrophy, Animal | Gentamicins | 4.98 | 18694830 | |
| MESH:D009139 | Musculoskeletal Abnormalities | sodium arsenate | 3.68 | 18186108 | |
| MESH:D009182 | Mycosis Fungoides | arsenic trioxide | 3.38 | 18349030 | |
| MESH:D009190 | Myelodysplastic Syndromes | arsenic trioxide | 13.41 | 16882451 16105982 | |
| MESH:D009190 | Myelodysplastic Syndromes | Azacitidine | 13.41 | 18720364 19805378 17611569 17596541 | |
| MESH:D009190 | Myelodysplastic Syndromes | decitabine | 13.41 | 16882708 18608210 19157545 19010910 | |
| MESH:D009190 | Myelodysplastic Syndromes | Dexamethasone | 13.41 | 9809623 | |
| MESH:D009190 | Myelodysplastic Syndromes | Tretinoin | 13.41 | 17596541 | |
| MESH:D009203 | Myocardial Infarction | Genistein | 7.26 | 17141266 | |
| MESH:D009203 | Myocardial Infarction | pirinixic acid | 7.26 | 19151258 | |
| MESH:D009203 | Myocardial Infarction | Quercetin | 7.26 | 19595682 | |
| MESH:D009203 | Myocardial Infarction | resveratrol | 7.26 | 16456233 16525036 16317513 17188708 17015251 17125593 | |
| MESH:D017202 | Myocardial Ischemia | resveratrol | 5.37 | 17125593 17015251 | |
| MESH:D017202 | Myocardial Ischemia | Tetrachlorodibenzodioxin | 5.37 | 12213967 | |
| MESH:D015428 | Myocardial Reperfusion Injury | Estradiol | 11.55 | 16810080 | |
| MESH:D015428 | Myocardial Reperfusion Injury | Genistein | 11.55 | 17141266 | |
| MESH:D015428 | Myocardial Reperfusion Injury | pirinixic acid | 11.55 | 16411023 | |
| MESH:D015428 | Myocardial Reperfusion Injury | Quercetin | 11.55 | 19207477 | |
| MESH:D009205 | Myocarditis | Particulate Matter | 8.21 | 12563109 | |
| MESH:D009205 | Myocarditis | resveratrol | 8.21 | 17322642 | |
| MESH:D009325 | Nausea | vorinostat | 4.24 | 20479100 | |
| MESH:D009336 | Necrosis | Melatonin | 4.21 | 12195237 | |
| MESH:D009361 | Neoplasm Invasiveness | arsenic trioxide | 6.27 | 16624393 | |
| MESH:D009361 | Neoplasm Invasiveness | Curcumin | 6.27 | 18495463 | |
| MESH:D009362 | Neoplasm Metastasis | Diethylnitrosamine | 5.21 | 3581430 9029167 | |
| MESH:D009362 | Neoplasm Metastasis | Indomethacin | 5.21 | 16537180 11239499 11053908 | |
| MESH:D009362 | Neoplasm Metastasis | Tamoxifen | 5.21 | 19393235 | |
| MESH:D009364 | Neoplasm Recurrence, Local | Tamoxifen | 1.92 | 19410462 | |
| MESH:D009369 | Neoplasms | 2,4,5,2',4',5'-hexachlorobiphenyl | 30.72 | 8820588 | |
| MESH:D009369 | Neoplasms | 9,10-Dimethyl-1,2-benzanthracene | 30.72 | 11544531 | |
| MESH:D009369 | Neoplasms | Benzo(a)pyrene | 30.72 | 11141357 | |
| MESH:D009369 | Neoplasms | Cyclophosphamide | 30.72 | 18854779 | |
| MESH:D009369 | Neoplasms | DDT | 30.72 | 8820588 | |
| MESH:D009369 | Neoplasms | decitabine | 30.72 | 19470736 19116145 17925555 | |
| MESH:D009369 | Neoplasms | Dieldrin | 30.72 | 8820588 | |
| MESH:D009369 | Neoplasms | Diethylstilbestrol | 30.72 | 15313581 | |
| MESH:D009369 | Neoplasms | Lindane | 30.72 | 16818664 12807735 | |
| MESH:D009369 | Neoplasms | pirinixic acid | 30.72 | 17405874 | |
| MESH:D009369 | Neoplasms | Quercetin | 30.72 | 15185748 | |
| MESH:D009369 | Neoplasms | sodium arsenite | 30.72 | 11559025 | |
| MESH:D009369 | Neoplasms | Tretinoin | 30.72 | 16594593 16946489 | |
| MESH:D009369 | Neoplasms | Trichloroethylene | 30.72 | 11911487 | |
| MESH:D009374 | Neoplasms, Experimental | Indomethacin | 8.26 | 10663608 15625704 | |
| MESH:D009374 | Neoplasms, Experimental | resveratrol | 8.26 | 8985016 | |
| MESH:D009374 | Neoplasms, Experimental | sodium arsenite | 8.26 | 20056578 | |
| MESH:D009376 | Neoplasms, Hormone-Dependent | bexarotene | 10.93 | 19196722 | |
| MESH:D009376 | Neoplasms, Hormone-Dependent | Curcumin | 10.93 | 12497104 | |
| MESH:D009376 | Neoplasms, Hormone-Dependent | Tamoxifen | 10.93 | 19189210 19196722 19200415 | |
| MESH:D009389 | Neovascularization, Pathologic | arsenite | 5.97 | 15738583 | |
| MESH:D009389 | Neovascularization, Pathologic | Estradiol | 5.97 | 17289903 | |
| MESH:D009402 | Nephrosis, Lipoid | Cyclosporine | 3.14 | 17954296 | |
| MESH:D009404 | Nephrotic Syndrome | Cyclosporine | 2.16 | 19348381 18481113 | |
| MESH:D009410 | Nerve Degeneration | Paraquat | 2.67 | 16893418 | |
| MESH:D009421 | Nervous System Malformations | bisphenol A | 22.76 | 16427766 11399458 | |
| MESH:D009421 | Nervous System Malformations | Diethylstilbestrol | 22.76 | 11399458 | |
| MESH:D009421 | Nervous System Malformations | Estradiol | 22.76 | 16427766 11399458 | |
| MESH:D009421 | Nervous System Malformations | Genistein | 22.76 | 16427766 | |
| MESH:D009421 | Nervous System Malformations | Tetrachlorodibenzodioxin | 22.76 | 14600291 | |
| MESH:D009421 | Nervous System Malformations | Tretinoin | 22.76 | 9125849 | |
| MESH:D009423 | Nervous System Neoplasms | Curcumin | 4.33 | 18462866 | |
| MESH:D009436 | Neural Tube Defects | arsenic trioxide | 15.83 | 10525206 | |
| MESH:D009436 | Neural Tube Defects | Benzene | 15.83 | 15643154 | |
| MESH:D009436 | Neural Tube Defects | sodium arsenate | 15.83 | 18186108 10525206 19446573 11749123 | |
| MESH:D009436 | Neural Tube Defects | sodium arsenite | 15.83 | 12854658 | |
| MESH:D009436 | Neural Tube Defects | Tretinoin | 15.83 | 9142499 | |
| MESH:D009436 | Neural Tube Defects | Vitamin A | 15.83 | 17400914 | |
| MESH:D019954 | Neurobehavioral Manifestations | 2,3',4,4',5-pentachlorobiphenyl | 8.57 | 19647017 | |
| MESH:D019954 | Neurobehavioral Manifestations | Plant Extracts | 8.57 | 17168769 | |
| MESH:D009447 | Neuroblastoma | Cyclophosphamide | 2.82 | 16115947 8761367 15176712 | |
| MESH:D019636 | Neurodegenerative Diseases | Diethylnitrosamine | 11.15 | 20387270 | |
| MESH:D019636 | Neurodegenerative Diseases | Indomethacin | 11.15 | 12349958 | |
| MESH:D019636 | Neurodegenerative Diseases | resveratrol | 11.15 | 17652729 | |
| MESH:D019636 | Neurodegenerative Diseases | Sulindac | 11.15 | 17266991 16850258 | |
| MESH:D017599 | Neuroectodermal Tumors | Cyclophosphamide | 3.62 | 8761367 12837982 | |
| MESH:D020078 | Neurogenic Inflammation | Quercetin | 6.70 | 17929310 | |
| MESH:D020078 | Neurogenic Inflammation | resveratrol | 6.70 | 17929310 | |
| MESH:D009461 | Neurologic Manifestations | Diethylnitrosamine | 3.82 | 20387270 | |
| MESH:D009503 | Neutropenia | Cyclophosphamide | 5.58 | 8291058 | |
| MESH:D009503 | Neutropenia | Mustard Gas | 5.58 | 7688884 16761898 | |
| MESH:D009765 | Obesity | Curcumin | 5.94 | 19297423 | |
| MESH:D009765 | Obesity | Dietary Fats | 5.94 | 20518802 16723640 19632207 18457598 18674790 21332399 20132043 11836018 17217161 | |
| MESH:D009765 | Obesity | pirinixic acid | 5.94 | 20558911 | |
| MESH:D009765 | Obesity | Plant Extracts | 5.94 | 20132043 19056576 | |
| MESH:D007752 | Obstetric Labor, Premature | Indomethacin | 3.87 | 6374098 | |
| MESH:D009784 | Occupational Diseases | Benzene | 3.05 | 17119257 15612468 15576619 15727169 17479406 15935809 17178637 15913788 16737584 | |
| MESH:D009845 | Oligospermia | Cyclophosphamide | 3.45 | 16517039 | |
| MESH:D010003 | Osteoarthritis | Indomethacin | 2.76 | 7009135 | |
| MESH:D010024 | Osteoporosis | Calcium | 9.22 | 17882678 | |
| MESH:D010024 | Osteoporosis | Curcumin | 9.22 | 18719352 | |
| MESH:D010024 | Osteoporosis | Genistein | 9.22 | 19401787 | |
| MESH:D010024 | Osteoporosis | kaempferol | 9.22 | 16756079 | |
| MESH:D015663 | Osteoporosis, Postmenopausal | Drugs, Chinese Herbal | 14.32 | 16548355 | |
| MESH:D015663 | Osteoporosis, Postmenopausal | Genistein | 14.32 | 16169203 | |
| MESH:D015663 | Osteoporosis, Postmenopausal | Quercetin | 14.32 | 19495926 | |
| MESH:D015663 | Osteoporosis, Postmenopausal | resveratrol | 14.32 | 17513867 | |
| MESH:D010049 | Ovarian Diseases | bisphenol A | 3.71 | 11985600 | |
| MESH:D010051 | Ovarian Neoplasms | marker/mechanism | 17372243 | ||
| MESH:D010051 | Ovarian Neoplasms | 9,10-Dimethyl-1,2-benzanthracene | 33.94 | 16891317 | |
| MESH:D010051 | Ovarian Neoplasms | arsenic trioxide | 33.94 | 19769630 16624393 12452020 | |
| MESH:D010051 | Ovarian Neoplasms | Benzene | 33.94 | 12562636 | |
| MESH:D010051 | Ovarian Neoplasms | Curcumin | 33.94 | 18462866 19020741 | |
| MESH:D010051 | Ovarian Neoplasms | decitabine | 33.94 | 19331143 19259094 | |
| MESH:D010051 | Ovarian Neoplasms | Estradiol | 33.94 | 19401270 | |
| MESH:D010051 | Ovarian Neoplasms | Genistein | 33.94 | 19005980 | |
| MESH:D010051 | Ovarian Neoplasms | Medroxyprogesterone Acetate | 33.94 | 17393432 | |
| MESH:D010051 | Ovarian Neoplasms | Mifepristone | 33.94 | 16525653 | |
| MESH:D010051 | Ovarian Neoplasms | Progesterone | 33.94 | 16525653 17393432 | |
| MESH:D010051 | Ovarian Neoplasms | Quercetin | 33.94 | 19005980 | |
| MESH:D010051 | Ovarian Neoplasms | sodium arsenite | 33.94 | 15276417 17306315 | |
| MESH:D010051 | Ovarian Neoplasms | Tretinoin | 33.94 | 16936753 | |
| MESH:D010051 | Ovarian Neoplasms | trichostatin A | 33.94 | 19331143 | |
| MESH:D010146 | Pain | Cyclophosphamide | 7.41 | 18093676 12161096 | |
| MESH:D010146 | Pain | Indomethacin | 7.41 | 17440234 17627676 13679232 3291741 | |
| MESH:D010146 | Pain | Sulindac | 7.41 | 3291741 | |
| MESH:D010146 | Pain | Tretinoin | 7.41 | 16870215 | |
| MESH:D010149 | Pain, Postoperative | Indomethacin | 3.40 | 12538197 18702446 | |
| MESH:D010190 | Pancreatic Neoplasms | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 26.19 | 12384795 | |
| MESH:D010190 | Pancreatic Neoplasms | arsenic trioxide | 26.19 | 15580305 | |
| MESH:D010190 | Pancreatic Neoplasms | Curcumin | 26.19 | 19196508 17440100 19401701 | |
| MESH:D010190 | Pancreatic Neoplasms | Cyclophosphamide | 26.19 | 11332152 | |
| MESH:D010190 | Pancreatic Neoplasms | decitabine | 26.19 | 19294695 | |
| MESH:D010190 | Pancreatic Neoplasms | Diethylnitrosamine | 26.19 | 16540662 | |
| MESH:D010190 | Pancreatic Neoplasms | Quercetin | 26.19 | 16965848 | |
| MESH:D010190 | Pancreatic Neoplasms | Sulindac | 26.19 | 16820089 11504793 | |
| MESH:D010190 | Pancreatic Neoplasms | Tetradecanoylphorbol Acetate | 26.19 | 15976015 | |
| MESH:D010190 | Pancreatic Neoplasms | Tretinoin | 26.19 | 15976015 | |
| MESH:D010190 | Pancreatic Neoplasms | trichostatin A | 26.19 | 19294695 | |
| MESH:D010195 | Pancreatitis | Indomethacin | 2.78 | 15028970 17883296 | |
| MESH:D016584 | Panic Disorder | Ethinyl Estradiol | 2.48 | 11578682 | |
| MESH:D010212 | Papilloma | 9,10-Dimethyl-1,2-benzanthracene | 12.25 | 15173996 17234724 16517061 | |
| MESH:D010212 | Papilloma | Hydrogen Peroxide | 12.25 | 12065085 | |
| MESH:D010212 | Papilloma | Plant Extracts | 12.25 | 16517061 15173996 | |
| MESH:D010212 | Papilloma | Tetradecanoylphorbol Acetate | 12.25 | 12065085 8330346 18404319 18922899 | |
| MESH:D010235 | Paraganglioma | arsenic trioxide | 2.96 | 19927285 | |
| MESH:D010257 | Paraneoplastic Syndromes | Indomethacin | 4.42 | 16537180 | |
| MESH:D010300 | Parkinson Disease | Dieldrin | 4.80 | 17291500 11445065 16809432 16112328 11181820 | |
| MESH:D010300 | Parkinson Disease | Paraquat | 4.80 | 11445065 12911755 16510128 11124998 15451049 11181820 16140633 15824117 | |
| MESH:D010300 | Parkinson Disease | Polychlorinated Biphenyls | 4.80 | 16702228 | |
| MESH:D010302 | Parkinson Disease, Secondary | Paraquat | 3.19 | 16190885 | |
| MESH:D020734 | Parkinsonian Disorders | Indomethacin | 5.92 | 12349958 | |
| MESH:D020734 | Parkinsonian Disorders | Melatonin | 5.92 | 15574749 | |
| MESH:D051302 | Paroxysmal Hemicrania | Indomethacin | 4.42 | 11903285 | |
| MESH:D010382 | Peliosis Hepatis | Tetrachlorodibenzodioxin | 2.95 | 12520081 | |
| MESH:D010437 | Peptic Ulcer | Indomethacin | 3.87 | 11148446 | |
| MESH:D010518 | Periodontitis | Indomethacin | 3.62 | 17225004 | |
| MESH:D010538 | Peritonitis | Melatonin | 6.46 | 15707874 | |
| MESH:D010538 | Peritonitis | Ozone | 6.46 | 16369182 | |
| MESH:C537884 | Peters anomaly | marker/mechanism | |||
| MESH:D010787 | Photosensitivity Disorders | 4-hydroxy-2-nonenal | 4.21 | 11550810 | |
| MESH:D010900 | Pituitary Diseases | Diethylstilbestrol | 3.87 | 14722030 | |
| MESH:D010911 | Pituitary Neoplasms | Diethylstilbestrol | 3.42 | 16977796 15687265 | |
| MESH:D011014 | Pneumonia | Ozone | 6.86 | 18007984 18929643 18381685 | |
| MESH:D011014 | Pneumonia | Paraquat | 6.86 | 12504350 | |
| MESH:D011041 | Poisoning | Mustard Gas | 2.65 | 15727166 | |
| MESH:D017119 | Porphyria Cutanea Tarda | Hexachlorobenzene | 7.03 | 9918132 | |
| MESH:D017119 | Porphyria Cutanea Tarda | Tetrachlorodibenzodioxin | 7.03 | 18163543 | |
| MESH:D011230 | Precancerous Conditions | 1-phenylazo-2-naphthol | 12.76 | 2563599 | |
| MESH:D011230 | Precancerous Conditions | Cyclosporine | 12.76 | 12371664 | |
| MESH:D011230 | Precancerous Conditions | Diethylnitrosamine | 12.76 | 2563599 | |
| MESH:D011230 | Precancerous Conditions | Quercetin | 12.76 | 19056647 | |
| MESH:D054198 | Precursor Cell Lymphoblastic Leukemia-Lymphoma | Cyclophosphamide | 4.81 | 21297632 | |
| MESH:D054198 | Precursor Cell Lymphoblastic Leukemia-Lymphoma | Dexamethasone | 4.81 | 21297632 | |
| MESH:D011248 | Pregnancy Complications | 2,4-Dichlorophenoxyacetic Acid | 4.49 | 2087686 | |
| MESH:D047928 | Premature Birth | Indomethacin | 3.87 | 17000239 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | bisphenol A | 13.03 | 10548101 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | Diethylstilbestrol | 13.03 | 17184923 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | resveratrol | 13.03 | 16679765 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | Tetrachlorodibenzodioxin | 13.03 | 11896295 11118676 11222880 11399792 | |
| MESH:D055728 | Primary Myelofibrosis | decitabine | 8.27 | 17616702 | |
| MESH:D055728 | Primary Myelofibrosis | trichostatin A | 8.27 | 17616702 | |
| MESH:D019048 | Prostatic Intraepithelial Neoplasia | bisphenol A | 6.62 | 20887781 | |
| MESH:D019048 | Prostatic Intraepithelial Neoplasia | Estradiol | 6.62 | 20887781 | |
| MESH:D011471 | Prostatic Neoplasms | marker/mechanism | 17704407 | ||
| MESH:D011471 | Prostatic Neoplasms | Apigenin | 11.51 | 17132221 | |
| MESH:D011471 | Prostatic Neoplasms | arsenic trioxide | 11.51 | 19131511 | |
| MESH:D011471 | Prostatic Neoplasms | Azacitidine | 11.51 | 18324645 | |
| MESH:D011471 | Prostatic Neoplasms | Benzo(a)pyrene | 11.51 | 17292933 | |
| MESH:D011471 | Prostatic Neoplasms | biochanin A | 11.51 | 12111696 | |
| MESH:D011471 | Prostatic Neoplasms | bisphenol A | 11.51 | 16740699 | |
| MESH:D011471 | Prostatic Neoplasms | Curcumin | 11.51 | 18769126 12497104 11398177 18156803 15129424 18226269 10851300 | |
| MESH:D011471 | Prostatic Neoplasms | Cyclophosphamide | 11.51 | 17136230 | |
| MESH:D011471 | Prostatic Neoplasms | DDT | 11.51 | 12584743 | |
| MESH:D011471 | Prostatic Neoplasms | Diethylstilbestrol | 11.51 | 15846301 15046698 17136230 | |
| MESH:D011471 | Prostatic Neoplasms | docetaxel | 11.51 | 19103299 18824434 16520278 16644109 | |
| MESH:D011471 | Prostatic Neoplasms | Estradiol | 11.51 | 16740699 | |
| MESH:D011471 | Prostatic Neoplasms | Genistein | 11.51 | 15378649 15256057 16925846 | |
| MESH:D011471 | Prostatic Neoplasms | Ketoconazole | 11.51 | 17404083 | |
| MESH:D011471 | Prostatic Neoplasms | Lindane | 11.51 | 12661182 14688026 | |
| MESH:D011471 | Prostatic Neoplasms | Plant Extracts | 11.51 | 17804756 14666653 | |
| MESH:D011471 | Prostatic Neoplasms | Polychlorinated Biphenyls | 11.51 | 15721890 | |
| MESH:D011471 | Prostatic Neoplasms | Quercetin | 11.51 | 17292933 14715546 | |
| MESH:D011471 | Prostatic Neoplasms | resveratrol | 11.51 | 17718901 17675339 17636462 17804756 16731767 15767336 | |
| MESH:D011471 | Prostatic Neoplasms | sodium arsenite | 11.51 | 16039940 | |
| MESH:D011471 | Prostatic Neoplasms | Tamoxifen | 11.51 | 15067354 | |
| MESH:D011471 | Prostatic Neoplasms | trichostatin A | 11.51 | 19789329 18798265 | |
| MESH:D011471 | Prostatic Neoplasms | vorinostat | 11.51 | 17218635 | |
| MESH:D011507 | Proteinuria | Gentamicins | 8.73 | 15033597 | |
| MESH:D011507 | Proteinuria | Indomethacin | 8.73 | 11849393 | |
| MESH:D011507 | Proteinuria | Tretinoin | 8.73 | 16636307 | |
| MESH:D011537 | Pruritus | Ethinyl Estradiol | 5.36 | 15861022 16919318 | |
| MESH:D011537 | Pruritus | Mustard Gas | 5.36 | 18058305 | |
| MESH:D011565 | Psoriasis | Cyclosporine | 1.61 | 16882103 | |
| MESH:D011625 | Pterygium | Tretinoin | 3.51 | 16723453 | |
| MESH:D011629 | Puberty, Precocious | bisphenol A | 3.51 | 10548101 | |
| MESH:D011656 | Pulmonary Emphysema | Curcumin | 3.36 | 19168576 | |
| MESH:D011658 | Pulmonary Fibrosis | Cyclophosphamide | 9.66 | 16636934 | |
| MESH:D011658 | Pulmonary Fibrosis | Drugs, Chinese Herbal | 9.66 | 16987627 | |
| MESH:D011658 | Pulmonary Fibrosis | Mustard Gas | 9.66 | 17894541 10334151 17620002 17720292 17266442 | |
| MESH:D011658 | Pulmonary Fibrosis | Paraquat | 9.66 | 17997886 16324872 | |
| MESH:D011658 | Pulmonary Fibrosis | Particulate Matter | 9.66 | 12475806 | |
| MESH:D012003 | Rectal Fistula | Drugs, Chinese Herbal | 4.67 | 15043669 | |
| MESH:D051437 | Renal Insufficiency | Gentamicins | 3.76 | 17132701 15728788 | |
| MESH:D051436 | Renal Insufficiency, Chronic | resveratrol | 4.28 | 16325855 | |
| MESH:D015427 | Reperfusion Injury | pirinixic acid | 3.80 | 19058328 | |
| MESH:D015427 | Reperfusion Injury | resveratrol | 3.80 | 15827377 16314181 17520802 16317513 17058453 | |
| MESH:D012128 | Respiratory Distress Syndrome, Adult | Curcumin | 8.40 | 10666014 18379247 | |
| MESH:D012128 | Respiratory Distress Syndrome, Adult | Dexamethasone | 8.40 | 18379247 11700416 | |
| MESH:D012128 | Respiratory Distress Syndrome, Adult | Paraquat | 8.40 | 11700416 | |
| MESH:D012127 | Respiratory Distress Syndrome, Newborn | Vitamin A | 4.52 | 16877224 | |
| MESH:D012135 | Respiratory Sounds | Paraquat | 9.23 | 11874814 | |
| MESH:D012135 | Respiratory Sounds | Tobacco Smoke Pollution | 9.23 | 18410779 | |
| MESH:D012135 | Respiratory Sounds | Vehicle Emissions | 9.23 | 18950799 | |
| MESH:D015619 | Respiratory System Abnormalities | Tetrachlorodibenzodioxin | 2.60 | 18990726 | |
| MESH:D012162 | Retinal Degeneration | Paraquat | 2.82 | 16458197 | |
| MESH:D012173 | Retinitis | Gentamicins | 4.98 | 18644591 | |
| MESH:D012208 | Rhabdomyosarcoma | decitabine | 6.95 | 19155313 | |
| MESH:D012208 | Rhabdomyosarcoma | Tretinoin | 6.95 | 16283617 16116481 | |
| MESH:D012221 | Rhinitis, Allergic, Perennial | Drugs, Chinese Herbal | 3.99 | 15015336 | |
| MESH:D012468 | Salivary Gland Neoplasms | Progesterone | 2.21 | 18045962 | |
| MESH:D012509 | Sarcoma | Curcumin | 2.98 | 18462866 | |
| MESH:D012512 | Sarcoma, Ewing's | arsenic trioxide | 6.53 | 16646077 | |
| MESH:D012512 | Sarcoma, Ewing's | Dactinomycin | 6.53 | 14601052 | |
| MESH:D012554 | Schistosomiasis japonica | Quercetin | 4.25 | 16862918 | |
| MESH:D012595 | Scleroderma, Systemic | Cyclophosphamide | 3.62 | 16636934 | |
| MESH:D012640 | Seizures | Lindane | 3.63 | 12842176 7539098 15475178 | |
| MESH:D012640 | Seizures | Toluene | 3.63 | 9294310 6431079 | |
| MESH:D018805 | Sepsis | Curcumin | 2.97 | 18389075 | |
| MESH:D012871 | Skin Diseases | Mustard Gas | 3.49 | 12880345 16961503 15451306 | |
| MESH:D012871 | Skin Diseases | Vitamin A | 3.49 | 18709164 | |
| MESH:D012878 | Skin Neoplasms | 9,10-Dimethyl-1,2-benzanthracene | 30.82 | 15173996 8985016 16517061 11376689 | |
| MESH:D012878 | Skin Neoplasms | Benzo(a)pyrene | 30.82 | 10029692 19755658 | |
| MESH:D012878 | Skin Neoplasms | Hydrogen Peroxide | 30.82 | 12065085 | |
| MESH:D012878 | Skin Neoplasms | Okadaic Acid | 30.82 | 12628509 | |
| MESH:D012878 | Skin Neoplasms | Plant Extracts | 30.82 | 15173996 16517061 | |
| MESH:D012878 | Skin Neoplasms | resveratrol | 30.82 | 8985016 15837718 | |
| MESH:D012878 | Skin Neoplasms | sodium arsenite | 30.82 | 19524636 18572023 | |
| MESH:D012878 | Skin Neoplasms | tert-Butylhydroperoxide | 30.82 | 8532709 | |
| MESH:D012878 | Skin Neoplasms | Tetrachlorodibenzodioxin | 30.82 | 16192470 | |
| MESH:D012878 | Skin Neoplasms | Tetradecanoylphorbol Acetate | 30.82 | 11807781 12065085 18404319 8985016 8330346 | |
| MESH:D012878 | Skin Neoplasms | Tobacco Smoke Pollution | 30.82 | 18590791 | |
| MESH:D012878 | Skin Neoplasms | Tretinoin | 30.82 | 16467112 | |
| MESH:D012893 | Sleep Disorders | Melatonin | 4.21 | 16919138 16897403 18182647 | |
| MESH:D020178 | Sleep Disorders, Circadian Rhythm | Melatonin | 5.33 | 18078449 19452292 | |
| MESH:D007319 | Sleep Initiation and Maintenance Disorders | Melatonin | 3.99 | 18078449 | |
| MESH:D013088 | Spermatocele | Diethylstilbestrol | 12.73 | 16002989 16709447 | |
| MESH:D013088 | Spermatocele | Ethinyl Estradiol | 12.73 | 16709447 | |
| MESH:D013088 | Spermatocele | Tamoxifen | 12.73 | 16709447 | |
| OMIM:102530 | SPERMATOGENIC FAILURE 6 | Cyclophosphamide | 4.23 | 16517039 | |
| MESH:D013119 | Spinal Cord Injuries | Progesterone | 6.67 | 15862959 16503802 | |
| MESH:D013119 | Spinal Cord Injuries | Tamoxifen | 6.67 | 19457130 | |
| MESH:D016135 | Spinal Dysraphism | sodium arsenite | 2.72 | 12854658 | |
| MESH:D013158 | Splenic Diseases | aniline | 9.79 | 15694462 | |
| MESH:D013158 | Splenic Diseases | Grape Seed Proanthocyanidins | 9.79 | 12587719 | |
| MESH:D013272 | Stomach Diseases | Dexamethasone | 9.89 | 15472012 | |
| MESH:D013272 | Stomach Diseases | Indomethacin | 9.89 | 17160473 15038085 18545984 10486359 16184426 17207306 16280098 10215738 18209964 15472012 10192188 16113693 17638125 | |
| MESH:D013272 | Stomach Diseases | Omeprazole | 9.89 | 18545984 | |
| MESH:D013274 | Stomach Neoplasms | arsenic trioxide | 10.19 | 17007042 | |
| MESH:D013274 | Stomach Neoplasms | Benzene | 10.19 | 12562636 | |
| MESH:D013274 | Stomach Neoplasms | Benzo(a)pyrene | 10.19 | 2093021 20155912 | |
| MESH:D013274 | Stomach Neoplasms | decitabine | 10.19 | 19037991 | |
| MESH:D013274 | Stomach Neoplasms | Diethylnitrosamine | 10.19 | 18456281 | |
| MESH:D013274 | Stomach Neoplasms | docetaxel | 10.19 | 16557585 | |
| MESH:D013274 | Stomach Neoplasms | Drugs, Chinese Herbal | 10.19 | 18339527 | |
| MESH:D013274 | Stomach Neoplasms | Indomethacin | 10.19 | 15609394 | |
| MESH:D013274 | Stomach Neoplasms | Tretinoin | 10.19 | 17261132 | |
| MESH:D013274 | Stomach Neoplasms | Zidovudine | 10.19 | 17696246 | |
| MESH:D013276 | Stomach Ulcer | Curcumin | 16.50 | 16631530 19188055 | |
| MESH:D013276 | Stomach Ulcer | Dexamethasone | 16.50 | 15138204 | |
| MESH:D013276 | Stomach Ulcer | Indomethacin | 16.50 | 17918041 11523592 10423059 18087811 10878458 17135157 16934674 18299717 16150113 18543354 17627676 12467913 18431645 18237397 16755016 12498302 12077510 11729361 18209962 14567935 10750652 11145282 15104355 12500499 15138204 16169175 11906479 12787963 18181030 18726076 17895592 17654042 17977527 11595431 1323529 15255614 16397915 17657623 16631530 11595415 16252198 18193104 | |
| MESH:D013276 | Stomach Ulcer | lansoprazole | 16.50 | 18726076 11906479 18087811 17918041 17895592 | |
| MESH:D013276 | Stomach Ulcer | Melatonin | 16.50 | 16150113 11523592 12500499 | |
| MESH:D013276 | Stomach Ulcer | Omeprazole | 16.50 | 15991576 10750652 17977527 16755016 18237397 11906479 | |
| MESH:D013276 | Stomach Ulcer | Plant Extracts | 16.50 | 18237397 15255614 17135157 18193104 12787963 | |
| OMIM:601367 | STROKE, ISCHEMIC | resveratrol | 3.32 | 16321402 | |
| MESH:D013345 | Subarachnoid Hemorrhage | Drugs, Chinese Herbal | 9.39 | 17634840 | |
| MESH:D013345 | Subarachnoid Hemorrhage | pifithrin | 9.39 | 18364113 | |
| MESH:D019966 | Substance-Related Disorders | bisphenol A | 2.74 | 16045194 16684133 | |
| MESH:D015173 | Supratentorial Neoplasms | Cyclophosphamide | 3.78 | 12837982 | |
| MESH:D013705 | Temporomandibular Joint Disorders | Plant Extracts | 4.18 | 17997062 | |
| MESH:D013733 | Testicular Diseases | Toluene | 3.70 | 10514026 10048760 | |
| MESH:D013921 | Thrombocytopenia | vorinostat | 3.83 | 20479100 | |
| MESH:D019851 | Thrombophilia | Ethinyl Estradiol | 2.42 | 11994571 | |
| MESH:D013927 | Thrombosis | Ethinyl Estradiol | 2.04 | 15669648 | |
| MESH:D013953 | Thymus Neoplasms | Benzene | 3.68 | 10850423 | |
| MESH:D013959 | Thyroid Diseases | Tetrachlorodibenzodioxin | 2.61 | 12697716 | |
| MESH:D013964 | Thyroid Neoplasms | arsenic trioxide | 11.40 | 19014326 | |
| MESH:D013964 | Thyroid Neoplasms | decitabine | 11.40 | 17967635 | |
| MESH:D013964 | Thyroid Neoplasms | Diethylnitrosamine | 11.40 | 7505956 | |
| MESH:D013964 | Thyroid Neoplasms | Indomethacin | 11.40 | 11352223 14736730 18791128 | |
| MESH:D013964 | Thyroid Neoplasms | Tretinoin | 11.40 | 16026305 17045167 | |
| MESH:D013978 | Tibial Fractures | Estradiol | 3.39 | 19048282 | |
| MESH:D014062 | Tongue Neoplasms | resveratrol | 6.07 | 16227395 | |
| MESH:D014062 | Tongue Neoplasms | Tretinoin | 6.07 | 16051514 | |
| MESH:D016171 | Torsades de Pointes | arsenic trioxide | 2.71 | 15213294 | |
| MESH:D014376 | Tuberculosis | Tretinoin | 2.29 | 16040207 | |
| MESH:D014456 | Ulcer | Indomethacin | 3.62 | 17380554 10574470 | |
| MESH:D001749 | Urinary Bladder Neoplasms | 2-Acetylaminofluorene | 30.57 | 15289314 1399818 15867355 | |
| MESH:D001749 | Urinary Bladder Neoplasms | arsenic trioxide | 30.57 | 12845720 20435036 12973940 11780464 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Benzo(a)pyrene | 30.57 | 17053015 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Curcumin | 30.57 | 18593936 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Cyclophosphamide | 30.57 | 14692829 | |
| MESH:D001749 | Urinary Bladder Neoplasms | decitabine | 30.57 | 19087683 17616700 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Diethylstilbestrol | 30.57 | 17306315 16452187 16712894 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Plant Preparations | 30.57 | 11251952 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Quercetin | 30.57 | 16720314 | |
| MESH:D001749 | Urinary Bladder Neoplasms | sodium arsenite | 30.57 | 11723127 16712894 16452187 17306315 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Tamoxifen | 30.57 | 17572228 16712894 8653321 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Tobacco Smoke Pollution | 30.57 | 12846360 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Vehicle Emissions | 30.57 | 11144890 | |
| MESH:D014565 | Urogenital Neoplasms | Curcumin | 3.98 | 18462866 | |
| MESH:D014570 | Urologic Diseases | DDT | 8.44 | 16487989 | |
| MESH:D014570 | Urologic Diseases | Dichlorodiphenyl Dichloroethylene | 8.44 | 16487989 | |
| MESH:D002583 | Uterine Cervical Neoplasms | Diethylstilbestrol | 17.60 | 16175088 | |
| MESH:D002583 | Uterine Cervical Neoplasms | indole-3-carbinol | 17.60 | 16082211 | |
| MESH:D002583 | Uterine Cervical Neoplasms | resveratrol | 17.60 | 17473185 | |
| MESH:D002583 | Uterine Cervical Neoplasms | sodium arsenite | 17.60 | 11813266 | |
| MESH:D002583 | Uterine Cervical Neoplasms | Tretinoin | 17.60 | 16129372 | |
| MESH:D014591 | Uterine Diseases | bisphenol A | 9.53 | 14652134 | |
| MESH:D014591 | Uterine Diseases | Diethylstilbestrol | 9.53 | 14652134 | |
| MESH:D014594 | Uterine Neoplasms | Benzene | 21.82 | 12562636 | |
| MESH:D014594 | Uterine Neoplasms | Diethylstilbestrol | 21.82 | 15809267 16690809 | |
| MESH:D014594 | Uterine Neoplasms | Ethinyl Estradiol | 21.82 | 14692618 | |
| MESH:D014594 | Uterine Neoplasms | resveratrol | 21.82 | 17044934 | |
| MESH:D014594 | Uterine Neoplasms | Sulindac | 21.82 | 18645019 | |
| MESH:D014594 | Uterine Neoplasms | sulindac sulfide | 21.82 | 18645019 | |
| MESH:D014604 | Uveal Neoplasms | decitabine | 8.54 | 17785578 | |
| MESH:D014604 | Uveal Neoplasms | Tretinoin | 8.54 | 16752155 | |
| MESH:D014605 | Uveitis | Cyclosporine | 7.49 | 1336536 | |
| MESH:D014605 | Uveitis | Dexamethasone | 7.49 | 1336536 | |
| MESH:D014625 | Vaginal Neoplasms | Diethylstilbestrol | 7.00 | 16002989 16513791 | |
| MESH:D014625 | Vaginal Neoplasms | Zidovudine | 7.00 | 12579204 | |
| MESH:D014652 | Vascular Diseases | sodium arsenite | 3.15 | 17056641 | |
| MESH:D054079 | Vascular Malformations | Tetrachlorodibenzodioxin | 3.29 | 12125929 | |
| MESH:D020301 | Vasospasm, Intracranial | pifithrin | 4.35 | 18364113 | |
| MESH:D020246 | Venous Thrombosis | Ethinyl Estradiol | 2.36 | 14671159 15869587 | |
| MESH:D018487 | Ventricular Dysfunction, Left | Plant Extracts | 6.42 | 18097624 | |
| MESH:D018487 | Ventricular Dysfunction, Left | resveratrol | 6.42 | 17488730 | |
| MESH:D020257 | Ventricular Remodeling | Plant Extracts | 4.04 | 18097624 | |
| MESH:D015837 | Vestibular Diseases | Gentamicins | 4.28 | 18776599 | |
| MESH:D014802 | Vitamin A Deficiency | Vitamin A | 4.07 | 16960172 16175781 16146918 | |
| MESH:D014820 | Vitiligo | Tretinoin | 2.83 | 16761959 | |
| MESH:D014839 | Vomiting | Indomethacin | 3.46 | 11897121 | |
| MESH:D019282 | Wasting Syndrome | Tetrachlorodibenzodioxin | 2.95 | 15886252 | |
| MESH:D015430 | Weight Gain | Dietary Fats | 2.61 | 16723640 | |
| MESH:D009396 | Wilms Tumor | Tretinoin | 2.83 | 16287080 | |
| MESH:D014947 | Wounds and Injuries | Drugs, Chinese Herbal | 8.15 | 16313111 | |
| MESH:D014947 | Wounds and Injuries | Estrogens | 8.15 | 11172683 | |
| MESH:D014947 | Wounds and Injuries | Plant Extracts | 8.15 | 20213670 19894650 | |
| MESH:D014985 | Xerophthalmia | Cyclosporine | 3.14 | 17120751 |
| Pathway ID | Pathway Name |
|---|---|
| REACT:13433 | Biological oxidations |
| KEGG:00980 | Metabolism of xenobiotics by cytochrome P450 |
| KEGG:00140 | Steroid hormone biosynthesis |
| KEGG:00380 | Tryptophan metabolism |
| Releated gene ID | Related gene Name |
|---|---|
| PA27094 | CYP1B1 |
| PA378 | NR1I2 |
| Releated disease ID | Related disease Name |
|---|---|
| PA447278 | Depression |
| PA446852 | Hot Flashes |
| PA446411 | Endometrial Neoplasms |
| PA443622 | Carcinoma, Non-Small-Cell Lung |
| PA444818 | Lung Neoplasms |
| PA444281 | Glaucoma |
| PA445425 | Prostatic Neoplasms |
| PA445062 | Neoplasms |
| PA443937 | Drug Toxicity |
| PA443560 | Breast Neoplasms |
| PA446108 | Colorectal Neoplasms |
| PA445742 | Stomach Neoplasms |
| Releated drug ID | Related drug Name |
|---|---|
| PA164754789 | conjugated estrogens |
| PA449512 | estrone |
| PA451123 | progesterone |
| PA448404 | amodiaquine |
| PA448803 | carboplatin |
| PA449383 | docetaxel |
| PA134521193 | coumarin |
| PA449212 | daunorubicin |
| PA449165 | cyclophosphamide |
| PA449412 | doxorubicin |
| PA450761 | paclitaxel |
| PA449509 | estrogens |
| PA450704 | omeprazole |
| PA452604 | xenobiotics |
| PA449957 | ibuprofen |
| No data |
| Drugbank ID | Action | Drug Name | Description |
|---|---|---|---|
| DB00121 | inducer | Biotin | Dietary supplement;Micronutrient;Vitamins (Vitamin B Complex);Vitamin B Complex |
| DB00201 | substrate | Wigraine Tab | Central Nervous System Stimulants;Anorexigenic Agents;Phosphodiesterase Inhibitors |
| DB00277 | substrate | Theophylline rougier elixir | Vasodilator Agents;Phosphodiesterase Inhibitors;Bronchodilator Agents;Respiratory Smooth Muscle Relaxants |
| DB00338 | inducer | Omeprazole | Anti-Ulcer Agents;Enzyme Inhibitors;Proton-pump Inhibitors |
| DB00363 | inducer | Clozapine | Antipsychotics;Serotonin Antagonists;Antipsychotic Agents;GABA Antagonists |
| DB00396 | substrate | Synovex S | Contraceptives;Progestins |
| DB00448 | inducer | Lansoprazole | Anti-Infective Agents;Anti-Infectives;Anti-Ulcer Agents;Enzyme Inhibitors;Proton-pump Inhibitors |
| DB00499 | inhibitor | Flutamide | Antineoplastic Agents, Hormonal;Androgen Antagonists |
| DB00526 | substrate | Oxaliplatin | Antineoplastic Agents |
| DB00530 | substrate | Erlotinib | Protein Kinase Inhibitors |
| DB00613 | substrate | Camoprima Infatabs | Antimalarials;Amebicides |
| DB00624 | substrate | Uni-Bol | Androgens |
| DB00655 | substrate | Holis 98 | Antineoplastic Agents;Estrogens;Osteoporosis Prophylactic;Anti-menopausal Agents |
| DB00675 | inhibitor | Tamoxifen | Antineoplastic Agents, Hormonal;Selective Estrogen Receptor Modulators;Estrogen Antagonists;Bone Density Conservation Agents |
| DB00694 | inhibitor | Daunorubicin | Antineoplastic Agents;Antibiotics;Antibiotics, Antineoplastic |
| DB00783 | substrate | Triquilar 21 | Anticholesteremic Agents;Estrogens;Anti-menopausal Agents |
| DB00818 | inhibitor | Propofol | Free Radical Scavengers;Hypnotics and Sedatives;Antiemetics;Anticonvulsants;Anesthetics, Intravenous |
| DB00997 | inhibitor | Doxorubicin | Antineoplastic Agents;Antibiotics;Antibiotics, Antineoplastic |
| DB01026 | inhibitor | Ketoconazole | Antifungals;Antifungal Agents |
| DB01065 | inhibitor | Plenovit Melatonina | Antioxidants;Free Radical Scavengers;Anticonvulsants;Adjuvants, Immunologic;Central Nervous System Depressants |
| DB01087 | inducer | Primaquine | Antimalarials;Antiprotozoal Agents;Antimalarial Agents |
| DB01168 | substrate | Procarbazine | Antineoplastic Agents |
| DB01169 | inhibitor | Arsenic trioxide | Antineoplastic Agents;Homeopathic Agents |
| DB01204 | inhibitor | Mitoxantrone | Antineoplastic Agents;Analgesics |
| DB01229 | inhibitor | Paclitaxel | Antineoplastic Agents;Antineoplastic Agents, Phytogenic;Tubulin Modulators |
| DB01234 | inducer | Tresaderm Dermatologic Solution | Anti-inflammatory Agents;Adrenergic Agents;Antiemetics;Antineoplastic Agents, Hormonal;Glucocorticoids |
| DB01248 | inducer | Docetaxel | Antineoplastic Agents;Radiation-Sensitizing Agents;Antimalarials;Antineoplastic Agents, Phytogenic |
| DB01254 | substrate | Dasatinib | Protein Kinase Inhibitors |
| DB02709 | inhibitor | Resveratrol | Antioxidants;Platelet Aggregation Inhibitors;Enzyme Inhibitors;Anticarcinogenic Agents;Antineoplastic Agents, Phytogenic;Antimutagenic Agents |
| No data |
| No data |