AutismKB 2.0

Annotation Detail for RUNDC3B


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Basic Information Top
Gene Symbol:RUNDC3B ( FLJ30671,MGC26655,RPIB9,RPIP9 )
Gene Full Name: RUN domain containing 3B
Band: 7q21.12
Quick LinksEntrez ID:154661; OMIM: NA; Uniprot ID:RUN3B_HUMAN; ENSEMBL ID: ENSG00000105784; HGNC ID: 30286
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of RUNDC3B proteinaffects expression 20106945
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of RUNDC3B mRNAdecreases expression 20106945
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of RUNDC3B mRNAdecreases expression 19150397
20018196
D016572 Cyclosporine Cyclosporine results in decreased expression of RUNDC3B mRNAdecreases expression 20106945
D014635 Valproic Acid Valproic Acid results in increased expression of RUNDC3B mRNAincreases expression 19101580
D014810 Vitamin E Vitamin E results in decreased expression of RUNDC3B mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 3.958875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 4.2519490988
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0420127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 2.826695378
MESH:D000550 Amblyopia Valproic Acid 5.7517688650
MESH:D001008 Anxiety Disorders Valproic Acid 3.8317497229
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.4919183758
MESH:D001321 Autistic Disorder Valproic Acid 1.9917157402 17507914 17688650 18558336 16609825 15238991 18177632 19460635 18775368 19232924 18940202 20603192 18316065 18396377 18985861
MESH:D001714 Bipolar Disorder Valproic Acid 3.2120046352 17594078
MESH:D001848 Bone Diseases, Developmental Valproic Acid 3.598888407
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.0020146248 17474063
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.3516050911
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 1.9812907637 12619106 21507988
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1220419170
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.2620889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 7.2612371664
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.8020734317
MESH:D002779 Cholestasis Cyclosporine 3.1419486331
MESH:D019465 Craniofacial Abnormalities Valproic Acid 2.7917688650 8888407 16575769
MESH:D019465 Craniofacial Abnormalities Vitamin E 2.7919769572
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 2.241733752 19641884
MESH:D004421 Dystonia Valproic Acid 4.401851702
MESH:C538011 Eales disease Vitamin E 5.229068938
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.573659116 17275665
MESH:D004828 Epilepsies, Partial Valproic Acid 4.4416628512 3922381
MESH:D004827 Epilepsy Valproic Acid 3.0720417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 3.876254150 6426943 7562514
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.717750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.533659116
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.5720426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.5716530937
MESH:D005234 Fatty Liver Cyclosporine 8.8619224547
MESH:D005234 Fatty Liver Valproic Acid 8.8614986274 19224547
MESH:D005315 Fetal Diseases Valproic Acid 5.4116575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.5118558336 8888407
MESH:D005355 Fibrosis Cyclosporine 3.5612639820 12168785
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.688708960
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 7.1820471113
MESH:D006330 Heart Defects, Congenital Vitamin E 7.1816080930
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.8815720958
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.7916490937 16863852
MESH:D019584 Hot Flashes Vitamin E 4.4914716179
MESH:D006849 Hydrocephalus Valproic Acid 5.3317688650
MESH:D006973 Hypertension Cyclosporine 2.1910903974
MESH:D007251 Influenza, Human Vitamin E 4.7316624496
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.9615604871
MESH:D007674 Kidney Diseases Cyclosporine 6.578314463 18776723 10903974
MESH:D007674 Kidney Diseases Vitamin E 6.5712488133
MESH:D007680 Kidney Neoplasms Cyclosporine 3.0012371664
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.1916294345 17596541
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 1.9016169303
MESH:D008113 Liver Neoplasms Aflatoxin B1 4.899163691 15890375 2125692 18177683
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 4.8920195826 21137059
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 2.928603461
MESH:D008171 Lung Diseases Vitamin E 3.3716863852
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.7817228818
MESH:D008175 Lung Neoplasms Aflatoxin B1 3.6014755239
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 3.6018569708 6695378 18816296 17053015 20464547 20064080 20135361 18520028 20869020
MESH:D008175 Lung Neoplasms Vitamin E 3.6011062179
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.3116801185
MESH:D008881 Migraine Disorders Valproic Acid 3.4118803445 18765137
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.4316381670
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.358888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.3117596541
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3011141357
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.9617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.5719348381 18481113
MESH:D009436 Neural Tube Defects Valproic Acid 3.328888407 16359493
MESH:D011230 Precancerous Conditions Cyclosporine 3.5112371664
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 4.2920603192
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.1217292933
MESH:D011471 Prostatic Neoplasms Vitamin E 3.1215084515
MESH:D019310 Pseudolymphoma Valproic Acid 5.0611422049 12752131
MESH:D011565 Psoriasis Cyclosporine 2.3116882103
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.5319155313
MESH:D012559 Schizophrenia Valproic Acid 2.1015737665 19110320
MESH:D012640 Seizures Valproic Acid 2.941511512 11738929 11044598 17978042 3137016 16876388 14763951 15475178
MESH:D012871 Skin Diseases Vitamin E 2.5018709164
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.4910029692 19755658
MESH:D016135 Spinal Dysraphism Valproic Acid 4.0219490988
MESH:D013226 Status Epilepticus Valproic Acid 5.0612833885
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.5620155912 2093021
MESH:D020521 Stroke Vitamin E 3.7716517955
MESH:D014178 Translocation, Genetic Valproic Acid 5.7517262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.983119515
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.2817053015
MESH:D014564 Urogenital Abnormalities Valproic Acid 5.068888407
MESH:D014605 Uveitis Cyclosporine 4.501336536
MESH:D014985 Xerophthalmia Cyclosporine 4.9617120751
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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