Annotation Detail for CYP2E1
Basic Information Top
| Gene Symbol: | CYP2E1 ( CPE1,CYP2E,P450-J,P450C2E ) |
|---|---|
| Gene Full Name: | cytochrome P450, family 2, subfamily E, polypeptide 1 |
| Band: | 10q26.3 |
| Quick Links | Entrez ID:1571; OMIM: 124040; Uniprot ID:CP2E1_HUMAN; ENSEMBL ID: ENSG00000130649; HGNC ID: 2631 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Pathway ID | Pathway Name |
|---|---|
| PWY66-161 | oxidative ethanol degradation III (microsomal) |
| PWY-5453 | methylglyoxal degradation III |
| PWY-5451 | acetone degradation I (to methylglyoxal) |
| Pathway ID | Pathway Name |
|---|---|
| hsa00590 | Arachidonic acid metabolism |
| hsa00980 | Metabolism of xenobiotics by cytochrome P450 |
| hsa00982 | Drug metabolism - cytochrome P450 |
| hsa01100 | Metabolic pathways |
| hsa00591 | Linoleic acid metabolism |
| Pathway ID | Pathway Name |
|---|---|
| Biological oxidations |
| No data |
| No data |
| Pathway ID | Pathway Name |
|---|---|
| 500199 | CYP2E1 reactions |
| No data |
| No data |
| Desease Name |
|---|
| HEMATOLOGICAL |
| Liver Cirrhosis |
| oral cancer |
| adult brain tumors |
| Parkinson's disease |
| pneumonia |
| bronchitis |
| tuberculosis |
| colorectal cancer |
| CHEMDEPENDENCY |
| liver cancer |
| aplastic anemia, acquired |
| CANCER |
| liver disease |
| alcoholism |
| benzene toxicity |
| preterm birth |
| NEUROLOGICAL |
| METABOLIC |
| lung cancer |
| REPRODUCTION |
| INFECTION |
| genetic polymorphism |
| No data |
| No data |
| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| C072959 | 1,1,1,2-tetrafluoro-2-chloroethane | CYP2E1 protein results in increased metabolism of 1,1,1,2-tetrafluoro-2-chloroethane | increases metabolic processing | 1686224 |
| C495657 | 1,1,1-trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane | CYP2E1 protein results in increased hydroxylation of 1,1,1-trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane | increases hydroxylation | 9047321 |
| C068320 | 1,1-dichloro-1-fluoroethane | CYP2E1 protein affects the metabolism of 1,1-dichloro-1-fluoroethane | affects metabolic processing | 8104122 11684366 |
| C068320 | 1,1-dichloro-1-fluoroethane | CYP2E1 protein affects the susceptibility to 1,1-dichloro-1-fluoroethane | affects response to substance | 11407538 |
| C068320 | 1,1-dichloro-1-fluoroethane | CYP2E1 protein results in increased reduction of 1,1-dichloro-1-fluoroethane | increases reduction | 11407538 9173683 |
| C501196 | 1,1-dichloroethane | 1,1-dichloroethane results in increased activity of CYP2E1 protein | increases activity | 11606809 |
| C501196 | 1,1-dichloroethane | 1,1-dichloroethane results in increased expression of and results in increased activity of CYP2E1 protein | increases activity|increases expression | 11606809 |
| C501196 | 1,1-dichloroethane | 1,1-dichloroethane results in increased expression of CYP2E1 protein | increases expression | 11606809 |
| C030387 | 1,2,3,5-tetrachlorobenzene | CYP2E1 protein results in increased metabolism of 1,2,3,5-tetrachlorobenzene | increases metabolic processing | 7747284 |
| C030387 | 1,2,3,5-tetrachlorobenzene | CYP2E1 protein results in increased oxidation of 1,2,3,5-tetrachlorobenzene | increases oxidation | 7747284 |
| C018673 | 1,2,4,5-tetrachlorobenzene | 1,2,4,5-tetrachlorobenzene results in increased expression of CYP2E1 protein | increases expression | 10696772 |
| C009947 | 1,2,4-trichlorobenzene | CYP2E1 protein results in increased metabolism of 1,2,4-trichlorobenzene | increases metabolic processing | 7747284 |
| C009947 | 1,2,4-trichlorobenzene | CYP2E1 protein results in increased oxidation of 1,2,4-trichlorobenzene | increases oxidation | 7747284 |
| C410870 | 1,2,4-trihydroxy-9,10-anthracenedione | 1,2,4-trihydroxy-9,10-anthracenedione results in decreased activity of CYP2E1 protein | decreases activity | 12379470 |
| C035384 | 1,2-dichloroethylene | 1,2-dichloroethylene inhibits the reaction [CYP2E1 protein results in increased oxidation of 1,3-butadiene] | decreases reaction|increases oxidation | 10828257 |
| C035384 | 1,2-dichloroethylene | 1,2-dichloroethylene inhibits the reaction [Acetone results in increased activity of CYP2E1 protein] | decreases reaction|increases activity | 9851676 |
| C035384 | 1,2-dichloroethylene | 1,2-dichloroethylene inhibits the reaction [CYP2E1 protein affects the metabolism of Trichloroethylene] | affects metabolic processing|decreases reaction | 7871537 |
| C035384 | 1,2-dichloroethylene | 1,2-dichloroethylene inhibits the reaction [CYP2E1 protein affects the metabolism of Vinyl Chloride] | affects metabolic processing|decreases reaction | 7871537 |
| C035384 | 1,2-dichloroethylene | 1,2-dichloroethylene results in decreased activity of CYP2E1 protein | decreases activity | 9344893 20127315 15205388 9671540 |
| C035384 | 1,2-dichloroethylene | 1,2-dichloroethylene results in decreased expression of CYP2E1 protein | decreases expression | 9671540 |
| C035384 | 1,2-dichloroethylene | 1,2-dichloroethylene results in decreased activity of CYP2E1 protein | decreases activity | 9458004 |
| C031763 | 1,3-butadiene | CYP2E1 protein affects the metabolism of 1,3-butadiene | affects metabolic processing | 15470755 |
| C031763 | 1,3-butadiene | 1,2-dichloroethylene inhibits the reaction [CYP2E1 protein results in increased oxidation of 1,3-butadiene] | decreases reaction|increases oxidation | 10828257 |
| C031763 | 1,3-butadiene | 1-aminobenzotriazole inhibits the reaction [CYP2E1 protein results in increased oxidation of 1,3-butadiene] | decreases reaction|increases oxidation | 10828257 |
| C031763 | 1,3-butadiene | CYP2E1 protein results in increased oxidation of 1,3-butadiene | increases oxidation | 10828257 |
| C038983 | 1,3-dimethylthiourea | 1,3-dimethylthiourea results in increased expression of CYP2E1 protein | increases expression | 10190572 |
| C025223 | 1,4-dioxane | 1,4-dioxane results in increased activity of CYP2E1 protein | increases activity | 15490126 |
| C025223 | 1,4-dioxane | 1,4-dioxane results in increased expression of and results in increased activity of CYP2E1 protein | increases activity|increases expression | 15490126 |
| C025223 | 1,4-dioxane | 1,4-dioxane results in increased expression of CYP2E1 mRNA | increases expression | 15490126 |
| C035342 | 1,4-naphthoquinone | CYP2E1 protein results in increased abundance of 1,4-naphthoquinone | increases abundance | 16243959 |
| C055986 | 19-hydroxy-5,8,11,14-eicosatetraenoic acid | CYP2E1 protein affects the metabolism of 19-hydroxy-5,8,11,14-eicosatetraenoic acid | affects metabolic processing | 15205388 |
| C033020 | 1-aminobenzotriazole | 1-aminobenzotriazole results in decreased activity of CYP2E1 protein | decreases activity | 15618748 |
| C033020 | 1-aminobenzotriazole | 1-aminobenzotriazole inhibits the reaction [CYP2E1 protein affects the metabolism of Urethane] | affects metabolic processing|decreases reaction | 12704224 |
| C033020 | 1-aminobenzotriazole | 1-aminobenzotriazole inhibits the reaction [CYP2E1 protein results in increased oxidation of 1,3-butadiene] | decreases reaction|increases oxidation | 10828257 |
| C029350 | 1-naphthol | CYP2E1 protein results in increased abundance of 1-naphthol | increases abundance | 16243959 |
| C024336 | 1-phenylazo-2-naphthol | CYP2E1 protein results in increased oxidation of 1-phenylazo-2-naphthol | increases oxidation | 17159775 |
| C037738 | 1-phenylimidazole | 1-phenylimidazole inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] | decreases reaction|increases reduction | 7710944 |
| C037738 | 1-phenylimidazole | 1-phenylimidazole results in decreased activity of CYP2E1 protein | decreases activity | 7710944 |
| C067411 | 2,2-dichloro-1,1,1-trifluoroethane | 2,2-dichloro-1,1,1-trifluoroethane results in increased activity of CYP2E1 protein | increases activity | 12919722 |
| C067411 | 2,2-dichloro-1,1,1-trifluoroethane | CYP2E1 protein results in increased susceptibility to 2,2-dichloro-1,1,1-trifluoroethane | increases response to substance | 12451447 |
| C067411 | 2,2-dichloro-1,1,1-trifluoroethane | CYP2E1 protein results in increased metabolism of 2,2-dichloro-1,1,1-trifluoroethane | increases metabolic processing | 11684365 |
| C067411 | 2,2-dichloro-1,1,1-trifluoroethane | 2,2-dichloro-1,1,1-trifluoroethane results in decreased activity of CYP2E1 protein | decreases activity | 12378954 |
| C067411 | 2,2-dichloro-1,1,1-trifluoroethane | 2,2-dichloro-1,1,1-trifluoroethane results in decreased activity of CYP2E1 protein | decreases activity | 9144458 |
| C067411 | 2,2-dichloro-1,1,1-trifluoroethane | allyl sulfide inhibits the reaction [CYP2E1 protein results in increased metabolism of 2,2-dichloro-1,1,1-trifluoroethane] | decreases reaction|increases metabolic processing | 7956723 |
| C067411 | 2,2-dichloro-1,1,1-trifluoroethane | CYP2E1 protein affects the metabolism of 2,2-dichloro-1,1,1-trifluoroethane | affects metabolic processing | 11684366 11322177 8199305 |
| C067411 | 2,2-dichloro-1,1,1-trifluoroethane | CYP2E1 protein results in increased metabolism of 2,2-dichloro-1,1,1-trifluoroethane | increases metabolic processing | 7956723 |
| C067411 | 2,2-dichloro-1,1,1-trifluoroethane | CYP2E1 protein results in increased reduction of 2,2-dichloro-1,1,1-trifluoroethane | increases reduction | 9144458 |
| C039673 | 2,3,5,6-tetrachlorophenate | CYP2E1 protein results in increased oxidation of 2,3,5,6-tetrachlorophenate | increases oxidation | 7747284 |
| C056693 | 2,3,5-trichlorophenol | CYP2E1 protein results in increased oxidation of 2,3,5-trichlorophenol | increases oxidation | 7747284 |
| C076159 | 2,3-dichloro-1-propanol | CYP2E1 protein affects the susceptibility to 2,3-dichloro-1-propanol | affects response to substance | 9129171 |
| C085911 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of CYP2E1 mRNA | increases expression | 11306697 |
| C028519 | 2,6-dimethylnaphthalene | CYP2E1 protein results in increased oxidation of 2,6-dimethylnaphthalene | increases oxidation | 17156750 |
| C007766 | 2,6-xylidine | CYP2E1 protein affects the metabolism of 2,6-xylidine metabolite | affects metabolic processing | 11409937 |
| C007766 | 2,6-xylidine | fomepizole inhibits the reaction [CYP2E1 protein affects the metabolism of 2,6-xylidine metabolite] | affects metabolic processing|decreases reaction | 11409937 |
| C104935 | 2-(allylthio)pyrazine | 2-(allylthio)pyrazine inhibits the reaction [CYP2E1 protein results in increased hydroxylation of 4-nitrophenol] | decreases reaction|increases hydroxylation | 9065729 |
| C104935 | 2-(allylthio)pyrazine | 2-(allylthio)pyrazine inhibits the reaction [Isoniazid results in increased expression of CYP2E1 protein] | decreases reaction|increases expression | 9065729 |
| C104935 | 2-(allylthio)pyrazine | 2-(allylthio)pyrazine results in decreased activity of CYP2E1 protein | decreases activity | 9065729 |
| C104935 | 2-(allylthio)pyrazine | 2-(allylthio)pyrazine results in decreased expression of CYP2E1 mRNA | decreases expression | 9065729 |
| C104935 | 2-(allylthio)pyrazine | 2-(allylthio)pyrazine results in decreased expression of CYP2E1 protein | decreases expression | 9065729 |
| C003898 | 2-anisidine | CYP2E1 protein results in increased oxidation of 2-anisidine | increases oxidation | 15828049 |
| C003898 | 2-anisidine | CYP2E1 protein results in increased oxidation of 2-anisidine | increases oxidation | 16601807 |
| C034047 | 2-cresol | CYP2E1 protein affects the metabolism of 2-cresol | affects metabolic processing | 8592870 |
| C004726 | 2-dichlorobenzene | CYP2E1 protein results in increased metabolism of 2-dichlorobenzene | increases metabolic processing | 7747284 |
| C004726 | 2-dichlorobenzene | CYP2E1 protein results in increased oxidation of 2-dichlorobenzene | increases oxidation | 9817075 7747284 |
| C004726 | 2-dichlorobenzene | [Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene | increases activity|increases metabolic processing | 9817075 |
| C004726 | 2-dichlorobenzene | dihydroxyethyldithiocarbamate inhibits the reaction [[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene] | decreases reaction|increases activity|increases metabolic processing | 9817075 |
| C004726 | 2-dichlorobenzene | [Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene | increases activity|increases metabolic processing | 9817075 |
| C004726 | 2-dichlorobenzene | CYP2E1 protein results in increased oxidation of 2-dichlorobenzene | increases oxidation | 9817075 |
| C004726 | 2-dichlorobenzene | dihydroxyethyldithiocarbamate inhibits the reaction [[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene] | decreases reaction|increases activity|increases metabolic processing | 9817075 |
| C028405 | 2-naphthol | CYP2E1 protein results in increased abundance of 2-naphthol | increases abundance | 16243959 |
| C005328 | 2-nitroanisole | CYP2E1 protein results in increased metabolism of 2-nitroanisole | increases metabolic processing | 15144223 |
| C005328 | 2-nitroanisole | CYP2E1 protein results in increased oxidation of 2-nitroanisole | increases oxidation | 17159769 21218109 |
| C005328 | 2-nitroanisole | CYP2E1 protein results in increased oxidation of 2-nitroanisole | increases oxidation | 21218109 |
| C045573 | 2-nitrophenol | CYP2E1 protein affects the chemical synthesis of 2-nitrophenol | affects chemical synthesis | 11409192 |
| C045573 | 2-nitrophenol | CYP2E1 protein results in increased oxidation of 2-nitrophenol | increases oxidation | 17159769 |
| C045573 | 2-nitrophenol | CYP2E1 protein affects the chemical synthesis of 2-nitrophenol | affects chemical synthesis | 11409192 |
| C045573 | 2-nitrophenol | CYP2E1 protein affects the chemical synthesis of 2-nitrophenol | affects chemical synthesis | 11409192 |
| C045573 | 2-nitrophenol | CYP2E1 protein results in increased oxidation of 2-nitrophenol | increases oxidation | 20027144 |
| C026114 | 2-xylene | CYP2E1 protein results in increased metabolism of 2-xylene | increases metabolic processing | 8558417 |
| C026114 | 2-xylene | CYP2E1 protein results in increased oxidation of 2-xylene | increases oxidation | 17156750 |
| C026114 | 2-xylene | Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of 2-xylene] | decreases reaction|increases metabolic processing | 8558417 |
| C026114 | 2-xylene | 2-xylene results in increased expression of CYP2E1 protein | increases expression | 8996725 |
| C026114 | 2-xylene | Acetone promotes the reaction [2-xylene results in increased expression of CYP2E1 protein] | increases expression|increases reaction | 8996725 |
| C482258 | 3'-hydroxy-genistein | CYP2E1 protein results in increased chemical synthesis of 3'-hydroxy-genistein | increases chemical synthesis | 12814970 |
| C093383 | 3-methylbenzaldehyde | 3-methylbenzaldehyde results in decreased activity of CYP2E1 protein | decreases activity | 12791539 |
| C031285 | 3-xylene | CYP2E1 protein results in increased hydrolysis of 3-xylene | increases hydrolysis | 10353308 |
| C031285 | 3-xylene | CYP2E1 protein results in increased metabolism of 3-xylene | increases metabolic processing | 8558417 |
| C031285 | 3-xylene | CYP2E1 protein results in increased oxidation of 3-xylene | increases oxidation | 17156750 |
| C031285 | 3-xylene | Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of 3-xylene] | decreases reaction|increases metabolic processing | 8558417 |
| C031285 | 3-xylene | 3-xylene affects the activity of CYP2E1 protein | affects activity | 15204773 8598570 |
| C031285 | 3-xylene | 3-xylene promotes the reaction [CYP2E1 protein results in increased metabolism of Methylene Chloride] | increases metabolic processing|increases reaction | 8889796 |
| C031285 | 3-xylene | 3-xylene results in decreased activity of CYP2E1 protein | decreases activity | 12791539 |
| C031285 | 3-xylene | 3-xylene results in increased activity of CYP2E1 protein | increases activity | 8889796 |
| C031285 | 3-xylene | CYP2E1 protein results in increased oxidation of 3-xylene | increases oxidation | 18247580 |
| C106616 | 4,4'-dimethylbiphenyl | CYP2E1 protein results in increased oxidation of 4,4'-dimethylbiphenyl | increases oxidation | 17156750 |
| C027226 | (4-amidinophenyl)methanesulfonyl fluoride | (4-amidinophenyl)methanesulfonyl fluoride inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] | decreases reaction|increases degradation | 9143349 |
| C032538 | 4-cresol | CYP2E1 protein affects the metabolism of 4-cresol | affects metabolic processing | 8592870 |
| C018511 | 4-dichlorobenzene | CYP2E1 protein results in increased metabolism of 4-dichlorobenzene | increases metabolic processing | 7747284 |
| C018511 | 4-dichlorobenzene | CYP2E1 protein results in increased oxidation of 4-dichlorobenzene | increases oxidation | 9817075 7747284 |
| C018511 | 4-dichlorobenzene | 4-dichlorobenzene results in increased expression of CYP2E1 protein | increases expression | 10696772 |
| C018511 | 4-dichlorobenzene | [Isoniazid results in increased activity of CYP2E1 protein] which results in increased metabolism of 4-dichlorobenzene | increases activity|increases metabolic processing | 9051121 |
| C024836 | 4-nitrophenol | 4-nitrophenol inhibits the reaction [CYP2E1 protein results in increased metabolism of Theobromine] | decreases reaction|increases metabolic processing | 10215755 |
| C024836 | 4-nitrophenol | 4-nitrophenol inhibits the reaction [CYP2E1 protein results in increased oxidation of norflurane] | decreases reaction|increases oxidation | 1356728 |
| C024836 | 4-nitrophenol | Bucladesine promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol] | increases oxidation|increases reaction | 8531136 |
| C024836 | 4-nitrophenol | Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol] | decreases reaction|increases oxidation | 8531136 9143349 |
| C024836 | 4-nitrophenol | Cycloheximide inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol] | decreases reaction|increases oxidation | 8531136 9143349 |
| C024836 | 4-nitrophenol | Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]] | decreases reaction|increases oxidation|increases reaction | 9143349 |
| C024836 | 4-nitrophenol | CYP2E1 protein results in increased hydroxylation of 4-nitrophenol | increases hydroxylation | 15135088 14669323 8558417 |
| C024836 | 4-nitrophenol | CYP2E1 protein results in increased metabolism of 4-nitrophenol | increases metabolic processing | 9825833 15576447 12464242 |
| C024836 | 4-nitrophenol | CYP2E1 protein results in increased oxidation of 4-nitrophenol | increases oxidation | 10207612 9143349 11212141 8531136 |
| C024836 | 4-nitrophenol | Dimethylnitrosamine inhibits the reaction [Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]] | decreases reaction|increases oxidation | 8531136 |
| C024836 | 4-nitrophenol | Ethanol inhibits the reaction [Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]] | decreases reaction|increases oxidation | 8531136 |
| C024836 | 4-nitrophenol | Ethanol promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol] | increases oxidation|increases reaction | 8531136 8074729 |
| C024836 | 4-nitrophenol | ferric-adenosine triphosphate complex inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol] | decreases reaction|increases oxidation | 8531136 |
| C024836 | 4-nitrophenol | fomepizole inhibits the reaction [Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]] | decreases reaction|increases oxidation | 8531136 |
| C024836 | 4-nitrophenol | IL6 protein promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol] | increases oxidation|increases reaction | 8531136 |
| C024836 | 4-nitrophenol | Tetradecanoylphorbol Acetate inhibits the reaction [Cycloheximide inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]] | decreases reaction|increases oxidation | 8531136 |
| C024836 | 4-nitrophenol | Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol] | increases oxidation|increases reaction | 9143349 8531136 |
| C024836 | 4-nitrophenol | Tretinoin promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol] | increases oxidation|increases reaction | 8531136 |
| C024836 | 4-nitrophenol | CYP2E1 protein results in increased hydroxylation of 4-nitrophenol | increases hydroxylation | 10094576 15742976 |
| C024836 | 4-nitrophenol | 2-(allylthio)pyrazine inhibits the reaction [CYP2E1 protein results in increased hydroxylation of 4-nitrophenol] | decreases reaction|increases hydroxylation | 9065729 |
| C024836 | 4-nitrophenol | 4-nitrophenol inhibits the reaction [CYP2E1 protein results in increased metabolism of methylformamide] | decreases reaction|increases metabolic processing | 1538706 |
| C024836 | 4-nitrophenol | Acetone promotes the reaction [CYP2E1 protein results in increased hydroxylation of 4-nitrophenol] | increases hydroxylation|increases reaction | 8267643 |
| C024836 | 4-nitrophenol | allyl sulfide inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol] | decreases reaction|increases metabolic processing | 7601153 8117321 |
| C024836 | 4-nitrophenol | Chlormethiazole inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol] | decreases reaction|increases metabolic processing | 7601153 |
| C024836 | 4-nitrophenol | CYP2E1 protein results in increased hydroxylation of 4-nitrophenol | increases hydroxylation | 9618253 11408273 9065729 8267643 11911841 |
| C024836 | 4-nitrophenol | CYP2E1 protein results in increased metabolism of 4-nitrophenol | increases metabolic processing | 7601153 15763544 |
| C024836 | 4-nitrophenol | Ditiocarb inhibits the reaction [CYP2E1 protein results in increased hydroxylation of 4-nitrophenol] | decreases reaction|increases hydroxylation | 9618253 |
| C024836 | 4-nitrophenol | Ethanol promotes the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol] | increases metabolic processing|increases reaction | 7601153 |
| C024836 | 4-nitrophenol | phenethyl isothiocyanate inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol] | decreases reaction|increases metabolic processing | 7601153 |
| C024836 | 4-nitrophenol | pyridine promotes the reaction [CYP2E1 protein results in increased hydroxylation of 4-nitrophenol] | increases hydroxylation|increases reaction | 9618253 |
| C024836 | 4-nitrophenol | S-Adenosylmethionine inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol] | decreases reaction|increases metabolic processing | 15763544 |
| C016583 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | CYP2E1 protein affects the metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | affects metabolic processing | 12920169 |
| C016583 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | CYP2E1 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | increases metabolic processing | 12115524 |
| C016583 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of CYP2E1 protein | increases activity | 9774145 |
| C031286 | 4-xylene | CYP2E1 protein results in increased metabolism of 4-xylene | increases metabolic processing | 8558417 |
| C031286 | 4-xylene | CYP2E1 protein results in increased oxidation of 4-xylene | increases oxidation | 17156750 |
| C031286 | 4-xylene | Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-xylene] | decreases reaction|increases metabolic processing | 8558417 |
| C031286 | 4-xylene | 4-xylene results in increased activity of CYP2E1 protein | increases activity | 12781212 |
| C031286 | 4-xylene | Disulfiram inhibits the reaction [4-xylene results in increased activity of CYP2E1 protein] | decreases reaction|increases activity | 12781212 |
| C031286 | 4-xylene | CYP2E1 protein results in increased oxidation of 4-xylene | increases oxidation | 18247580 |
| C010643 | 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid | 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] | decreases reaction|increases degradation | 9143349 |
| C039289 | 6-hydroxychlorzoxazone | CYP2E1 protein results in increased chemical synthesis of 6-hydroxychlorzoxazone | increases chemical synthesis | 15155557 12401345 |
| C056033 | 7-ethoxy-4-trifluoromethylcoumarin | CYP2E1 protein results in decreased ethylation of 7-ethoxy-4-trifluoromethylcoumarin | decreases ethylation | 9241656 |
| C056033 | 7-ethoxy-4-trifluoromethylcoumarin | Orphenadrine inhibits the reaction [CYP2E1 protein results in decreased ethylation of 7-ethoxy-4-trifluoromethylcoumarin] | decreases ethylation|decreases reaction | 9241656 |
| C017299 | 7-ethoxycoumarin | CYP2E1 protein results in increased metabolism of 7-ethoxycoumarin | increases metabolic processing | 18385292 |
| C084236 | 7-hydroxy-4-trifluoromethylcoumarin | CYP2E1 protein results in increased chemical synthesis of 7-hydroxy-4-trifluoromethylcoumarin | increases chemical synthesis | 9241656 |
| C084236 | 7-hydroxy-4-trifluoromethylcoumarin | Orphenadrine inhibits the reaction [CYP2E1 protein results in increased chemical synthesis of 7-hydroxy-4-trifluoromethylcoumarin] | decreases reaction|increases chemical synthesis | 9241656 |
| C421010 | 9-(4'-aminophenyl)-9H-pyrido(3,4-b)indole | CYP2E1 protein results in increased chemical synthesis of 9-(4'-aminophenyl)-9H-pyrido(3,4-b)indole | increases chemical synthesis | 15279827 |
| C001969 | acephate | [acephate co-treated with vinclozolin] affects the expression of CYP2E1 protein | affects cotreatment|affects expression | 17686559 |
| C001969 | acephate | [fenarimol co-treated with acephate] affects the expression of CYP2E1 protein | affects cotreatment|affects expression | 17686559 |
| C001969 | acephate | [fenarimol co-treated with vinclozolin co-treated with acephate] affects the expression of CYP2E1 protein | affects cotreatment|affects expression | 17686559 |
| D000079 | Acetaldehyde | CYP2E1 protein results in increased metabolism of Acetaldehyde | increases metabolic processing | 10826103 |
| D000079 | Acetaldehyde | [CYP2E1 protein results in increased metabolism of Ethanol] which results in increased abundance of Acetaldehyde | increases abundance|increases metabolic processing | 18845238 |
| D000079 | Acetaldehyde | [CYP2E1 protein results in increased metabolism of Ethanol] which results in increased chemical synthesis of Acetaldehyde | increases chemical synthesis|increases metabolic processing | 7562599 |
| D000079 | Acetaldehyde | phenethyl isothiocyanate inhibits the reaction [[CYP2E1 protein results in increased metabolism of Ethanol] which results in increased chemical synthesis of Acetaldehyde] | decreases reaction|increases chemical synthesis|increases metabolic processing | 7562599 |
| D000082 | Acetaminophen | CYP2E1 protein results in increased metabolism of Acetaminophen | increases metabolic processing | 15576447 12464242 |
| D000082 | Acetaminophen | CYP2E1 protein results in increased susceptibility to Acetaminophen | increases response to substance | 11212141 |
| D000082 | Acetaminophen | Ethanol affects the reaction [CYP2E1 protein results in increased susceptibility to Acetaminophen] | affects reaction|increases response to substance | 11212141 |
| D000082 | Acetaminophen | Acetaminophen affects the expression of CYP2E1 mRNA | affects expression | 17562736 |
| D000082 | Acetaminophen | Acetaminophen results in decreased expression of CYP2E1 mRNA | decreases expression | 15576447 |
| D000082 | Acetaminophen | Acetaminophen results in decreased expression of CYP2E1 protein | decreases expression | 15576447 |
| D000082 | Acetaminophen | Acetaminophen results in increased activity of CYP2E1 protein | increases activity | 19799668 |
| D000082 | Acetaminophen | Acetaminophen results in increased expression of CYP2E1 mRNA | increases expression | 16393943 12958197 |
| D000082 | Acetaminophen | Acetaminophen results in increased expression of CYP2E1 protein | increases expression | 19002106 |
| D000082 | Acetaminophen | Carnosine inhibits the reaction [Acetaminophen results in increased activity of CYP2E1 protein] | decreases reaction|increases activity | 19799668 |
| D000082 | Acetaminophen | CYP2E1 protein results in increased metabolism of Acetaminophen | increases metabolic processing | 19002106 |
| D000082 | Acetaminophen | CYP2E1 protein results in increased metabolism of and affects the susceptibility to Acetaminophen | affects response to substance|increases metabolic processing | 11376689 |
| D000082 | Acetaminophen | CYP2E1 protein results in increased susceptibility to Acetaminophen | increases response to substance | 16557553 11323178 |
| D000082 | Acetaminophen | IL1A protein inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 protein] | decreases reaction|increases expression | 19002106 |
| D000082 | Acetaminophen | KITL protein inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA] | decreases reaction|increases expression | 12594235 |
| D000082 | Acetaminophen | PPARA protein affects the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA] | affects reaction|increases expression | 12958197 |
| D000082 | Acetaminophen | SLC13A1 protein affects the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA] | affects reaction|increases expression | 16729303 |
| D000082 | Acetaminophen | [Acetaminophen co-treated with Uranium analog] results in decreased expression of CYP2E1 mRNA | affects cotreatment|decreases expression | 17126469 |
| D000082 | Acetaminophen | Acetaminophen results in decreased expression of CYP2E1 mRNA | decreases expression | 17126469 |
| D000082 | Acetaminophen | Acetaminophen results in increased expression of CYP2E1 protein | increases expression | 18798224 |
| D000082 | Acetaminophen | Acetaminophen results in increased phosphorylation of and results in increased activity of CYP2E1 protein | increases activity|increases phosphorylation | 11562448 |
| D000082 | Acetaminophen | Choline deficiency promotes the reaction [Acetaminophen results in increased expression of CYP2E1 protein] | increases expression|increases reaction | 18798224 |
| D000082 | Acetaminophen | CYP2E1 protein affects the metabolism of Acetaminophen | affects metabolic processing | 15772367 |
| D000082 | Acetaminophen | Uranium analog promotes the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA] | increases expression|increases reaction | 17126469 |
| D000082 | Acetaminophen | YH 439 inhibits the reaction [Acetaminophen results in increased phosphorylation of and results in increased activity of CYP2E1 protein] | decreases reaction|increases activity|increases phosphorylation | 11562448 |
| D000096 | Acetone | CYP2E1 protein results in increased metabolism of Acetone | increases metabolic processing | 15576447 |
| D000096 | Acetone | Acetone results in increased expression of and results in increased activity of CYP2E1 protein | increases activity|increases expression | 8013281 |
| D000096 | Acetone | Acetone results in increased activity of CYP2E1 protein | increases activity | 8471070 |
| D000096 | Acetone | Acetone results in increased expression of CYP2E1 mRNA | increases expression | 8471070 |
| D000096 | Acetone | Acetone results in increased expression of CYP2E1 protein | increases expression | 8471070 |
| D000096 | Acetone | Alpha-Amanitin inhibits the reaction [Acetone results in increased expression of CYP2E1 mRNA] | decreases reaction|increases expression | 8471070 |
| D000096 | Acetone | 1,2-dichloroethylene inhibits the reaction [Acetone results in increased activity of CYP2E1 protein] | decreases reaction|increases activity | 9851676 |
| D000096 | Acetone | [Acetone co-treated with ciprofibrate] results in increased expression of CYP2E1 protein | affects cotreatment|increases expression | 7587954 |
| D000096 | Acetone | [Acetone co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 mRNA | affects cotreatment|decreases expression | 8734847 |
| D000096 | Acetone | [Acetone co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 protein | affects cotreatment|decreases expression | 8734847 |
| D000096 | Acetone | [Acetone co-treated with Methylcholanthrene] results in increased activity of CYP2E1 protein | affects cotreatment|increases activity | 8734847 |
| D000096 | Acetone | [Acetone co-treated with Methylcholanthrene] results in increased expression of CYP2E1 protein | affects cotreatment|increases expression | 8734847 |
| D000096 | Acetone | Acetone promotes the reaction [2-xylene results in increased expression of CYP2E1 protein] | increases expression|increases reaction | 8996725 |
| D000096 | Acetone | Acetone promotes the reaction [CYP2E1 protein results in increased hydroxylation of 4-nitrophenol] | increases hydroxylation|increases reaction | 8267643 |
| D000096 | Acetone | Acetone promotes the reaction [Toluene results in increased expression of CYP2E1 protein] | increases expression|increases reaction | 8996725 |
| D000096 | Acetone | Acetone results in increased activity of CYP2E1 protein | increases activity | 8734847 20127315 12919724 9851676 3782137 |
| D000096 | Acetone | Acetone results in increased expression of CYP2E1 mRNA | increases expression | 2241968 8267643 11939710 |
| D000096 | Acetone | Acetone results in increased expression of CYP2E1 protein | increases expression | 3782137 8734847 12919724 2241968 15763544 11939710 1968335 8267643 |
| D000096 | Acetone | Trichloroethylene inhibits the reaction [Acetone results in increased activity of CYP2E1 protein] | decreases reaction|increases activity | 9851676 |
| C032159 | acetonitrile | acetonitrile inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] | decreases reaction|increases degradation | 9143349 |
| D020106 | Acrylamide | Acrylamide affects the expression of CYP2E1 mRNA | affects expression | 17267090 |
| D020106 | Acrylamide | CYP2E1 protein affects the metabolism of Acrylamide | affects metabolic processing | 17979661 |
| D020106 | Acrylamide | CYP2E1 protein results in increased oxidation of Acrylamide | increases oxidation | 15355880 |
| D020106 | Acrylamide | CYP2E1 protein results in increased susceptibility to Acrylamide | increases response to substance | 17267090 15355880 |
| D000181 | Acrylonitrile | CYP2E1 protein affects the susceptibility to Acrylonitrile | affects response to substance | 20127315 |
| C058956 | acteoside | acteoside inhibits the reaction [Carbon Tetrachloride results in increased expression of and results in increased activity of CYP2E1 protein] | decreases reaction|increases activity|increases expression | 14672760 |
| D012436 | S-Adenosylmethionine | S-Adenosylmethionine results in decreased activity of CYP2E1 protein | decreases activity | 15763544 |
| D012436 | S-Adenosylmethionine | S-Adenosylmethionine promotes the reaction [Carbon Tetrachloride results in decreased expression of and results in decreased activity of CYP2E1 protein] | decreases activity|decreases expression|increases reaction | 15983038 |
| D012436 | S-Adenosylmethionine | S-Adenosylmethionine inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol] | decreases reaction|increases metabolic processing | 15763544 |
| D012436 | S-Adenosylmethionine | S-Adenosylmethionine inhibits the reaction [CYP2E1 protein results in increased metabolism of Dimethylnitrosamine] | decreases reaction|increases metabolic processing | 15763544 |
| D012436 | S-Adenosylmethionine | S-Adenosylmethionine inhibits the reaction [CYP2E1 protein results in increased metabolism of Ethanol] | decreases reaction|increases metabolic processing | 15763544 |
| D012436 | S-Adenosylmethionine | S-Adenosylmethionine results in decreased activity of CYP2E1 protein | decreases activity | 15763544 |
| D016604 | Aflatoxin B1 | Aflatoxin B1 affects the expression of CYP2E1 protein | affects expression | 20106945 |
| C010078 | alizarin | alizarin results in decreased activity of CYP2E1 protein | decreases activity | 12379470 |
| D000496 | Alloxan | Alloxan affects the reaction [CYP2E1 protein results in decreased methylation of Dimethylnitrosamine] | affects reaction|decreases methylation | 17034923 |
| D000496 | Alloxan | Alloxan results in increased expression of CYP2E1 protein | increases expression | 17034923 |
| C006463 | allyl alcohol | allyl alcohol results in increased expression of CYP2E1 protein | increases expression | 11515535 |
| C077207 | allyl methyl sulfide | allyl methyl sulfide results in decreased expression of CYP2E1 protein | decreases expression | 16000231 8117321 |
| C038491 | allyl sulfide | allyl sulfide results in decreased activity of CYP2E1 protein | decreases activity | 15974642 17034788 |
| C038491 | allyl sulfide | allyl sulfide inhibits the reaction [CYP2E1 protein results in increased metabolism of 2,2-dichloro-1,1,1-trifluoroethane] | decreases reaction|increases metabolic processing | 7956723 |
| C038491 | allyl sulfide | allyl sulfide inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol] | decreases reaction|increases metabolic processing | 7601153 8117321 |
| C038491 | allyl sulfide | allyl sulfide inhibits the reaction [CYP2E1 protein results in increased metabolism of aniline] | decreases reaction|increases metabolic processing | 8117321 |
| C038491 | allyl sulfide | allyl sulfide inhibits the reaction [CYP2E1 protein results in increased metabolism of Carbon Tetrachloride] | decreases reaction|increases metabolic processing | 7601153 |
| C038491 | allyl sulfide | allyl sulfide inhibits the reaction [CYP2E1 protein results in increased metabolism of Dimethylnitrosamine] | decreases reaction|increases metabolic processing | 8117321 |
| C038491 | allyl sulfide | allyl sulfide inhibits the reaction [Pyrazines results in increased activity of CYP2E1 protein] | decreases reaction|increases activity | 8117321 |
| C038491 | allyl sulfide | allyl sulfide inhibits the reaction [Pyrazines results in increased expression of CYP2E1 protein] | decreases reaction|increases expression | 8117321 |
| C038491 | allyl sulfide | allyl sulfide results in decreased activity of CYP2E1 protein | decreases activity | 7956723 |
| C038491 | allyl sulfide | allyl sulfide results in decreased expression of CYP2E1 protein | decreases expression | 8117321 16000231 7601153 |
| C038491 | allyl sulfide | allyl sulfide results in increased activity of CYP2E1 protein | increases activity | 15046820 |
| C038491 | allyl sulfide | allyl sulfide results in increased expression of CYP2E1 protein | increases expression | 8627517 |
| D053959 | Alpha-Amanitin | Alpha-Amanitin inhibits the reaction [Acetone results in increased expression of CYP2E1 mRNA] | decreases reaction|increases expression | 8471070 |
| C010177 | alpha-hederin | alpha-hederin results in decreased activity of CYP2E1 protein | decreases activity | 9861456 |
| C040534 | alpha-hexachlorocyclohexane | [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP2E1 protein | affects cotreatment|increases expression | 16246485 |
| D017962 | alpha-Linolenic Acid | alpha-Linolenic Acid results in decreased activity of CYP2E1 protein | decreases activity | 16978661 |
| D000640 | Amitrole | Amitrole results in decreased activity of CYP2E1 protein | decreases activity | 12464242 |
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of CYP2E1 mRNA | affects expression | 16483693 |
| D000728 | Androgens | Androgens results in decreased expression of CYP2E1 protein | decreases expression | 2785912 |
| C023650 | aniline | aniline results in decreased activity of CYP2E1 protein | decreases activity | 12814958 15306208 |
| C023650 | aniline | CYP2E1 protein affects the metabolism of [norharman co-treated with aniline] | affects cotreatment|affects metabolic processing | 15279827 |
| C023650 | aniline | CYP2E1 protein results in increased hydroxylation of aniline | increases hydroxylation | 9195021 8858968 |
| C023650 | aniline | CYP2E1 protein results in increased metabolism of aniline | increases metabolic processing | 8819299 12464242 |
| C023650 | aniline | Ethanol promotes the reaction [CYP2E1 protein results in increased oxidation of aniline] | increases oxidation|increases reaction | 8074729 |
| C023650 | aniline | Proadifen inhibits the reaction [CYP2E1 protein results in increased metabolism of aniline] | decreases reaction|increases metabolic processing | 8819299 |
| C023650 | aniline | CYP2E1 protein results in increased hydroxylation of aniline | increases hydroxylation | 9195021 |
| C023650 | aniline | Changkil inhibits the reaction [CYP2E1 protein results in increased hydroxylation of aniline] | decreases reaction|increases hydroxylation | 18291569 |
| C023650 | aniline | CYP2E1 protein results in increased hydroxylation of aniline | increases hydroxylation | 18291569 18436364 18038910 |
| C023650 | aniline | phenyl caffeate inhibits the reaction [CYP2E1 protein results in increased hydroxylation of aniline] | decreases reaction|increases hydroxylation | 18436364 |
| C023650 | aniline | puerarin inhibits the reaction [CYP2E1 protein results in increased hydroxylation of aniline] | decreases reaction|increases hydroxylation | 18038910 |
| C023650 | aniline | [CYP2E1 protein co-treated with POR protein] results in increased hydroxylation of aniline | affects cotreatment|increases hydroxylation | 2292581 |
| C023650 | aniline | allyl sulfide inhibits the reaction [CYP2E1 protein results in increased metabolism of aniline] | decreases reaction|increases metabolic processing | 8117321 |
| C023650 | aniline | [Grape Seed Proanthocyanidins results in decreased activity of CYP2E1 protein] which results in decreased hydroxylation of aniline | decreases activity|decreases hydroxylation | 11330834 |
| D000872 | Anthocyanins | Anthocyanins results in increased expression of CYP2E1 mRNA | increases expression | 18803703 |
| D016718 | Arachidonic Acid | [Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein | affects cotreatment|increases expression | 17034788 |
| D016718 | Arachidonic Acid | [[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT18 protein | affects cotreatment|increases expression | 17034788 |
| D016718 | Arachidonic Acid | [[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT8 protein | affects cotreatment|increases expression | 17034788 |
| D016718 | Arachidonic Acid | Arachidonic Acid results in decreased activity of CYP2E1 protein | decreases activity | 16978661 |
| D016718 | Arachidonic Acid | CYP2E1 protein affects the hydroxylation of Arachidonic Acid | affects hydroxylation | 15205388 |
| D001151 | Arsenic | Arsenic affects the expression of CYP2E1 mRNA | affects expression | 18414638 |
| C006632 | arsenic trioxide | arsenic trioxide affects the expression of CYP2E1 mRNA | affects expression | 17530438 |
| D001205 | Ascorbic Acid | Ascorbic Acid results in decreased activity of CYP2E1 protein | decreases activity | 17512695 |
| D001218 | Aspartame | Aspartame results in increased expression of and results in increased activity of CYP2E1 protein | increases activity|increases expression | 16937917 |
| D001241 | Aspirin | Aspirin results in increased expression of CYP2E1 mRNA | increases expression | 11752103 |
| D001280 | Atrazine | Atrazine results in increased expression of CYP2E1 protein | increases expression | 14961354 |
| D001397 | Azoxymethane | Azoxymethane results in decreased expression of CYP2E1 mRNA | decreases expression | 18038451 |
| D001554 | Benzene | CYP2E1 gene polymorphism affects the susceptibility to Benzene | affects response to substance | 16737589 15226677 17095285 |
| D001554 | Benzene | CYP2E1 gene polymorphism results in increased susceptibility to Benzene | increases response to substance | 15226677 |
| D001554 | Benzene | CYP2E1 protein affects the metabolism of Benzene | affects metabolic processing | 15226677 |
| D001554 | Benzene | CYP2E1 protein affects the susceptibility to Benzene | affects response to substance | 12460800 |
| D001554 | Benzene | CYP2E1 protein results in increased hydroxylation of Benzene | increases hydroxylation | 15122651 |
| D001554 | Benzene | CYP2E1 protein results in increased metabolism of Benzene | increases metabolic processing | 18350910 17885617 9817075 |
| D001554 | Benzene | CYP2E1 protein results in increased oxidation of Benzene | increases oxidation | 10207612 9817075 |
| D001554 | Benzene | AHR protein affects the reaction [Benzene results in increased expression of CYP2E1 protein] | affects reaction|increases expression | 12388843 |
| D001554 | Benzene | [Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene | increases activity|increases metabolic processing | 9817075 |
| D001554 | Benzene | Benzene results in increased expression of CYP2E1 mRNA | increases expression | 12928149 17157166 |
| D001554 | Benzene | Benzene results in increased expression of CYP2E1 protein | increases expression | 12388843 |
| D001554 | Benzene | CYP2E1 protein results in increased hydroxylation of Benzene | increases hydroxylation | 11718959 14718178 |
| D001554 | Benzene | CYP2E1 protein results in increased metabolism of Benzene | increases metabolic processing | 11376689 |
| D001554 | Benzene | dihydroxyethyldithiocarbamate inhibits the reaction [[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene] | decreases reaction|increases activity|increases metabolic processing | 9817075 |
| D001554 | Benzene | Benzene affects the expression of CYP2E1 mRNA | affects expression | 15878777 |
| D001554 | Benzene | Benzene promotes the reaction [CYP2E1 protein results in increased metabolism of Methylene Chloride] | increases metabolic processing|increases reaction | 8889796 |
| D001554 | Benzene | Benzene results in decreased activity of CYP2E1 protein | decreases activity | 18407866 |
| D001554 | Benzene | Benzene results in decreased expression of CYP2E1 protein | decreases expression | 15274493 |
| D001554 | Benzene | Benzene results in increased activity of CYP2E1 protein | increases activity | 8889796 12919724 |
| D001554 | Benzene | [Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene | increases activity|increases metabolic processing | 9817075 |
| D001554 | Benzene | [Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of chlorobenzene | increases activity|increases metabolic processing | 9817075 |
| D001554 | Benzene | Benzene results in increased expression of CYP2E1 mRNA | increases expression | 12919724 |
| D001554 | Benzene | Benzene results in increased expression of CYP2E1 protein | increases expression | 12919724 |
| D001554 | Benzene | dihydroxyethyldithiocarbamate inhibits the reaction [[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene] | decreases reaction|increases activity|increases metabolic processing | 9817075 |
| D001554 | Benzene | dihydroxyethyldithiocarbamate inhibits the reaction [[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of chlorobenzene] | decreases reaction|increases activity|increases metabolic processing | 9817075 |
| D001554 | Benzene | Progesterone promotes the reaction [Benzene results in decreased activity of CYP2E1 protein] | decreases activity|increases reaction | 18407866 |
| D001554 | Benzene | CYP2E1 protein results in increased metabolism of Benzene | increases metabolic processing | 15833037 |
| D019324 | beta-Naphthoflavone | beta-Naphthoflavone results in increased expression of CYP2E1 mRNA | increases expression | 19969063 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in decreased expression of CYP2E1 mRNA | decreases expression | 20127859 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of CYP2E1 mRNA | increases expression | 19889059 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of CYP2E1 protein | increases expression | 19889059 |
| D001589 | Benzphetamine | [CYP2E1 protein co-treated with POR protein] results in decreased methylation of Benzphetamine | affects cotreatment|decreases methylation | 2292581 |
| D019905 | Benzyl Alcohol | CYP2E1 protein affects the metabolism of Benzyl Alcohol | affects metabolic processing | 8592870 |
| D001592 | Benzyl Alcohols | CYP2E1 protein results in increased oxidation of Benzyl Alcohols | increases oxidation | 7515681 |
| C025383 | benzylideneacetone | CYP2E1 protein results in increased oxidation of benzylideneacetone | increases oxidation | 15863696 |
| C477843 | bicyclol | bicyclol results in increased activity of CYP2E1 protein | increases activity | 15998439 |
| C073710 | bilobalide | bilobalide results in increased activity of CYP2E1 protein | increases activity | 18421621 |
| D001710 | Biotin | Biotin inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] | decreases reaction|increases degradation | 9143349 |
| C032036 | bromobenzene | bromobenzene results in increased expression of CYP2E1 protein | increases expression | 10547960 |
| C032036 | bromobenzene | bromobenzene results in increased expression of CYP2E1 mRNA | increases expression | 12628495 |
| C025191 | bromodichloromethane | CYP2E1 protein results in increased metabolism of bromodichloromethane | increases metabolic processing | 12076521 18350910 12076522 |
| C025191 | bromodichloromethane | bromodichloromethane results in increased expression of CYP2E1 protein | increases expression | 11295256 |
| C025191 | bromodichloromethane | CYP2E1 protein results in increased metabolism of and results in increased activity of bromodichloromethane | increases activity|increases metabolic processing | 9458004 |
| C025191 | bromodichloromethane | CYP2E1 protein results in increased metabolism of bromodichloromethane | increases metabolic processing | 11295256 12076521 |
| D020122 | tert-Butylhydroperoxide | tert-Butylhydroperoxide promotes the reaction [t-butyl acetylene results in decreased activity of CYP2E1 protein] | decreases activity|increases reaction | 15379534 |
| D020122 | tert-Butylhydroperoxide | tert-Butylhydroperoxide promotes the reaction [t-butyl acetylene results in decreased activity of CYP2E1 protein mutant form] | decreases activity|increases reaction | 15379534 |
| C053400 | cafestol | cafestol results in decreased activity of CYP2E1 protein | decreases activity | 17590492 |
| C040048 | caffeic acid | caffeic acid inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] | decreases reaction|increases reduction | 7710944 |
| C055494 | caffeic acid phenethyl ester | [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CYP2E1 mRNA | affects cotreatment|decreases expression | 20360939 |
| D002110 | Caffeine | CYP2E1 protein affects the metabolism of Caffeine | affects metabolic processing | 14586387 |
| D002118 | Calcium | Calcium affects the expression of CYP2E1 mRNA | affects expression | 15913539 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol] | decreases reaction|increases oxidation | 9143349 8531136 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride promotes the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] | increases degradation|increases reaction | 9143349 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in increased activity of CYP2E1 protein | increases activity | 17710613 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in increased degradation of and results in decreased activity of CYP2E1 protein | decreases activity|increases degradation | 8531136 |
| D002251 | Carbon Tetrachloride | Cycloheximide promotes the reaction [Carbon Tetrachloride results in increased degradation of CYP2E1 protein] | increases degradation|increases reaction | 8531136 |
| D002251 | Carbon Tetrachloride | CYP2E1 protein results in increased metabolism of Carbon Tetrachloride | increases metabolic processing | 15797236 8531136 18350910 |
| D002251 | Carbon Tetrachloride | Dimethylnitrosamine inhibits the reaction [Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]] | decreases reaction|increases oxidation | 8531136 |
| D002251 | Carbon Tetrachloride | Dimethylnitrosamine inhibits the reaction [Carbon Tetrachloride results in increased degradation of CYP2E1 protein] | decreases reaction|increases degradation | 8531136 |
| D002251 | Carbon Tetrachloride | Ethanol inhibits the reaction [Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]] | decreases reaction|increases oxidation | 8531136 |
| D002251 | Carbon Tetrachloride | fomepizole inhibits the reaction [Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]] | decreases reaction|increases oxidation | 8531136 |
| D002251 | Carbon Tetrachloride | fomepizole inhibits the reaction [Carbon Tetrachloride results in increased degradation of CYP2E1 protein] | decreases reaction|increases degradation | 8531136 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in decreased activity of CYP2E1 protein | decreases activity | 17038628 17698563 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in decreased expression of and results in decreased activity of CYP2E1 protein | decreases activity|decreases expression | 15983038 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in decreased expression of CYP2E1 mRNA | decreases expression | 12759355 15962327 15056808 18038451 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in decreased expression of CYP2E1 protein | decreases expression | 12466116 15962327 16445600 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in increased expression of and results in increased activity of CYP2E1 protein | increases activity|increases expression | 10355542 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in increased expression of CYP2E1 protein | increases expression | 17610925 |
| D002251 | Carbon Tetrachloride | CDKN1A protein affects the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 mRNA] | affects reaction|decreases expression | 12759355 |
| D002251 | Carbon Tetrachloride | CYP2E1 gene mutant form inhibits the reaction [Carbon Tetrachloride results in decreased expression of BNIP3 mRNA] | decreases expression|decreases reaction | 17084009 |
| D002251 | Carbon Tetrachloride | CYP2E1 gene mutant form inhibits the reaction [Carbon Tetrachloride results in decreased expression of CAR3 mRNA] | decreases expression|decreases reaction | 17084009 |
| D002251 | Carbon Tetrachloride | CYP2E1 gene mutant form inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP1A2 mRNA] | decreases expression|decreases reaction | 17084009 |
| D002251 | Carbon Tetrachloride | CYP2E1 gene mutant form inhibits the reaction [Carbon Tetrachloride results in decreased expression of IL1RAP mRNA] | decreases expression|decreases reaction | 17084009 |
| D002251 | Carbon Tetrachloride | CYP2E1 gene mutant form inhibits the reaction [Carbon Tetrachloride results in decreased expression of PAH mRNA] | decreases expression|decreases reaction | 17084009 |
| D002251 | Carbon Tetrachloride | CYP2E1 protein affects the susceptibility to Carbon Tetrachloride | affects response to substance | 15962327 |
| D002251 | Carbon Tetrachloride | NUPR1 protein affects the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 mRNA] | affects reaction|decreases expression | 15962327 |
| D002251 | Carbon Tetrachloride | NUPR1 protein affects the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 protein] | affects reaction|decreases expression | 15962327 |
| D002251 | Carbon Tetrachloride | Oleanolic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of and results in increased activity of CYP2E1 protein] | decreases reaction|increases activity|increases expression | 10355542 |
| D002251 | Carbon Tetrachloride | S-Adenosylmethionine promotes the reaction [Carbon Tetrachloride results in decreased expression of and results in decreased activity of CYP2E1 protein] | decreases activity|decreases expression|increases reaction | 15983038 |
| D002251 | Carbon Tetrachloride | acteoside inhibits the reaction [Carbon Tetrachloride results in increased expression of and results in increased activity of CYP2E1 protein] | decreases reaction|increases activity|increases expression | 14672760 |
| D002251 | Carbon Tetrachloride | allyl sulfide inhibits the reaction [CYP2E1 protein results in increased metabolism of Carbon Tetrachloride] | decreases reaction|increases metabolic processing | 7601153 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride affects the expression of CYP2E1 mRNA | affects expression | 17805973 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in decreased activity of CYP2E1 protein | decreases activity | 14706259 16288784 17410408 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in decreased expression of CYP2E1 mRNA | decreases expression | 14706259 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in decreased expression of CYP2E1 protein | decreases expression | 17606319 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in increased activity of CYP2E1 protein | increases activity | 17710613 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in increased degradation of CYP2E1 protein | increases degradation | 12679053 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in increased expression of and results in increased activity of CYP2E1 protein | increases activity|increases expression | 14672760 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in increased expression of CYP2E1 mRNA | increases expression | 11903743 |
| D002251 | Carbon Tetrachloride | Chlormethiazole inhibits the reaction [CYP2E1 protein results in increased metabolism of Carbon Tetrachloride] | decreases reaction|increases metabolic processing | 7601153 |
| D002251 | Carbon Tetrachloride | CYP2E1 protein affects the metabolism of Carbon Tetrachloride | affects metabolic processing | 15772367 |
| D002251 | Carbon Tetrachloride | CYP2E1 protein results in increased metabolism of Carbon Tetrachloride | increases metabolic processing | 7601153 |
| D002251 | Carbon Tetrachloride | ebselen inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 mRNA] | decreases reaction|increases expression | 11903743 |
| D002251 | Carbon Tetrachloride | Ethanol promotes the reaction [CYP2E1 protein results in increased metabolism of Carbon Tetrachloride] | increases metabolic processing|increases reaction | 7601153 |
| D002251 | Carbon Tetrachloride | phenethyl isothiocyanate inhibits the reaction [CYP2E1 protein results in increased metabolism of Carbon Tetrachloride] | decreases reaction|increases metabolic processing | 7601153 |
| D002251 | Carbon Tetrachloride | Propolis inhibits the reaction [Carbon Tetrachloride results in decreased activity of CYP2E1 protein] | decreases activity|decreases reaction | 17410408 |
| D002251 | Carbon Tetrachloride | Silymarin inhibits the reaction [Carbon Tetrachloride results in decreased activity of CYP2E1 protein] | decreases activity|decreases reaction | 17410408 |
| D002251 | Carbon Tetrachloride | CYP2E1 protein results in increased metabolism of and results in increased activity of Carbon Tetrachloride | increases activity|increases metabolic processing | 16142352 |
| D002251 | Carbon Tetrachloride | CYP2E1 protein results in increased metabolism of Carbon Tetrachloride | increases metabolic processing | 15962327 |
| D002251 | Carbon Tetrachloride | [CYP2E1 protein results in increased metabolism of Carbon Tetrachloride] which results in increased abundance of trichloromethyl free radical | increases abundance|increases metabolic processing | 19336974 |
| D002331 | Carnitine | Carnitine promotes the reaction [Ethanol results in increased expression of CYP2E1 protein] | increases expression|increases reaction | 8130774 |
| D002336 | Carnosine | Carnosine inhibits the reaction [Acetaminophen results in increased activity of CYP2E1 protein] | decreases reaction|increases activity | 19799668 |
| C088453 | Celsior | Celsior results in decreased activity of CYP2E1 protein | decreases activity | 15448115 |
| C088453 | Celsior | Celsior results in decreased expression of CYP2E1 mRNA | decreases expression | 15448115 |
| C440574 | Changkil | Changkil inhibits the reaction [CYP2E1 protein results in increased hydroxylation of aniline] | decreases reaction|increases hydroxylation | 18291569 |
| D002719 | Chlormethiazole | Chlormethiazole inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol] | decreases reaction|increases metabolic processing | 7601153 |
| D002719 | Chlormethiazole | Chlormethiazole inhibits the reaction [CYP2E1 protein results in increased metabolism of Carbon Tetrachloride] | decreases reaction|increases metabolic processing | 7601153 |
| D002719 | Chlormethiazole | Chlormethiazole results in decreased activity of CYP2E1 protein | decreases activity | 16330492 |
| D002719 | Chlormethiazole | Chlormethiazole results in decreased expression of CYP2E1 mRNA | decreases expression | 10751552 |
| D002719 | Chlormethiazole | Chlormethiazole results in decreased expression of CYP2E1 protein | decreases expression | 7601153 10751552 |
| D002719 | Chlormethiazole | Chlormethiazole results in decreased activity of CYP2E1 protein | decreases activity | 16054987 |
| C031294 | chlorobenzene | CYP2E1 protein results in increased oxidation of chlorobenzene | increases oxidation | 9817075 |
| C031294 | chlorobenzene | dihydroxyethyldithiocarbamate inhibits the reaction [CYP2E1 protein results in increased metabolism of chlorobenzene] | decreases reaction|increases metabolic processing | 9817075 |
| C031294 | chlorobenzene | [Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of chlorobenzene | increases activity|increases metabolic processing | 9817075 |
| C031294 | chlorobenzene | CYP2E1 protein results in increased oxidation of chlorobenzene | increases oxidation | 9817075 |
| C031294 | chlorobenzene | dihydroxyethyldithiocarbamate inhibits the reaction [[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of chlorobenzene] | decreases reaction|increases activity|increases metabolic processing | 9817075 |
| D020111 | Chlorodiphenyl (54% Chlorine) | Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP2E1 mRNA | decreases expression | 17851650 |
| D020111 | Chlorodiphenyl (54% Chlorine) | Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP2E1 mRNA | decreases expression | 8471063 |
| D020111 | Chlorodiphenyl (54% Chlorine) | Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP2E1 protein | decreases expression | 3113478 |
| D002725 | Chloroform | CYP2E1 protein results in increased metabolism of Chloroform | increases metabolic processing | 18350910 |
| D002746 | Chlorpromazine | Chlorpromazine results in decreased activity of CYP2E1 protein | decreases activity | 15135088 |
| D002753 | Chlorzoxazone | [Chlorzoxazone results in decreased activity of CYP2E1 protein] which results in decreased degradation of vanoxerine | decreases activity|decreases degradation | 11502731 |
| D002753 | Chlorzoxazone | CYB5 protein promotes the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] | increases hydroxylation|increases reaction | 15728263 |
| D002753 | Chlorzoxazone | CYP2E1 protein affects the hydroxylation of Chlorzoxazone | affects hydroxylation | 7747284 |
| D002753 | Chlorzoxazone | CYP2E1 protein affects the metabolism of Chlorzoxazone | affects metabolic processing | 15327588 14586387 12818727 15626586 |
| D002753 | Chlorzoxazone | CYP2E1 protein results in increased hydroxylation of Chlorzoxazone | increases hydroxylation | 15728263 12690492 8858968 12433797 15255802 8558417 15618748 15802389 |
| D002753 | Chlorzoxazone | CYP2E1 protein results in increased metabolism of Chlorzoxazone | increases metabolic processing | 9825833 17565714 16124035 15370959 15155557 12401345 9817075 15576447 12464242 |
| D002753 | Chlorzoxazone | CYP2E1 protein results in increased oxidation of Chlorzoxazone | increases oxidation | 10207612 |
| D002753 | Chlorzoxazone | CYP2E1 protein affects the metabolism of Chlorzoxazone | affects metabolic processing | 15231049 15879494 |
| D002753 | Chlorzoxazone | CYP2E1 protein results in increased hydroxylation of Chlorzoxazone | increases hydroxylation | 15205388 11911841 |
| D002794 | Choline | Choline deficiency promotes the reaction [Acetaminophen results in increased expression of CYP2E1 protein] | increases expression|increases reaction | 18798224 |
| D002794 | Choline | Choline deficiency promotes the reaction [Phenobarbital results in increased expression of CYP2E1 protein] | increases expression|increases reaction | 18798224 |
| C029010 | cinnamic acid | cinnamic acid analog results in decreased activity of CYP2E1 protein | decreases activity | 15072549 |
| C019304 | ciprofibrate | [Acetone co-treated with ciprofibrate] results in increased expression of CYP2E1 protein | affects cotreatment|increases expression | 7587954 |
| C019304 | ciprofibrate | ciprofibrate results in increased expression of CYP2E1 mRNA | increases expression | 7587954 |
| C019304 | ciprofibrate | pyridine promotes the reaction [ciprofibrate results in increased expression of CYP2E1 protein] | increases expression|increases reaction | 7587954 |
| C019304 | ciprofibrate | [Thiazoles co-treated with ciprofibrate] results in increased expression of CYP2E1 protein | affects cotreatment|increases expression | 7587954 |
| D009249 | NADP | [vinyl carbamate co-treated with NADP] inhibits the reaction [CYP2E1 protein results in decreased methylation of Dimethylnitrosamine] | affects cotreatment|decreases methylation|decreases reaction | 11181492 |
| C007164 | cumene hydroperoxide | cumene hydroperoxide inhibits the reaction [t-butyl acetylene results in decreased activity of CYP2E1 protein mutant form] | decreases activity|decreases reaction | 15379534 |
| C007164 | cumene hydroperoxide | cumene hydroperoxide promotes the reaction [t-butyl acetylene results in decreased activity of CYP2E1 protein] | decreases activity|increases reaction | 15379534 |
| D003474 | Curcumin | Curcumin affects the expression of CYP2E1 protein | affects expression | 16805852 |
| D003474 | Curcumin | Curcumin results in increased expression of CYP2E1 mRNA | increases expression | 18539377 |
| D003486 | Cyanides | [CYP2E1 protein results in increased metabolism of methacrylonitrile] which results in increased abundance of Cyanides | increases abundance|increases metabolic processing | 15893539 |
| D003511 | Cyclohexanols | [Diethylnitrosamine co-treated with Cyclohexanols] results in increased expression of CYP2E1 protein | affects cotreatment|increases expression | 17393424 |
| D003513 | Cycloheximide | (4-amidinophenyl)methanesulfonyl fluoride inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] | decreases reaction|increases degradation | 9143349 |
| D003513 | Cycloheximide | 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] | decreases reaction|increases degradation | 9143349 |
| D003513 | Cycloheximide | acetonitrile inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] | decreases reaction|increases degradation | 9143349 |
| D003513 | Cycloheximide | Biotin inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] | decreases reaction|increases degradation | 9143349 |
| D003513 | Cycloheximide | Carbon Tetrachloride promotes the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] | increases degradation|increases reaction | 9143349 |
| D003513 | Cycloheximide | Cycloheximide inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol] | decreases reaction|increases oxidation | 9143349 8531136 |
| D003513 | Cycloheximide | Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]] | decreases reaction|increases oxidation|increases reaction | 9143349 |
| D003513 | Cycloheximide | Cycloheximide promotes the reaction [Carbon Tetrachloride results in increased degradation of CYP2E1 protein] | increases degradation|increases reaction | 8531136 |
| D003513 | Cycloheximide | Cycloheximide results in increased degradation of CYP2E1 protein | increases degradation | 9143349 |
| D003513 | Cycloheximide | Dimethyl Sulfoxide inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] | decreases reaction|increases degradation | 9143349 |
| D003513 | Cycloheximide | Edetic Acid inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] | decreases reaction|increases degradation | 9143349 |
| D003513 | Cycloheximide | Egtazic Acid inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] | decreases reaction|increases degradation | 9143349 |
| D003513 | Cycloheximide | Ethanol inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] | decreases reaction|increases degradation | 9143349 |
| D003513 | Cycloheximide | fomepizole inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] | decreases reaction|increases degradation | 9143349 |
| D003513 | Cycloheximide | Glycerol inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] | decreases reaction|increases degradation | 9143349 |
| D003513 | Cycloheximide | leupeptin inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] | decreases reaction|increases degradation | 9143349 |
| D003513 | Cycloheximide | Tetradecanoylphorbol Acetate inhibits the reaction [Cycloheximide inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]] | decreases reaction|increases oxidation | 8531136 |
| D003513 | Cycloheximide | Tosyllysine Chloromethyl Ketone inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] | decreases reaction|increases degradation | 9143349 |
| D003513 | Cycloheximide | Cycloheximide inhibits the reaction [pyridine results in increased activity of CYP2E1 protein] | decreases reaction|increases activity | 1968335 |
| D003513 | Cycloheximide | Cycloheximide inhibits the reaction [pyridine results in increased expression of CYP2E1 protein] | decreases reaction|increases expression | 1968335 |
| D016572 | Cyclosporine | Cyclosporine results in decreased expression of CYP2E1 mRNA | decreases expression | 20106945 |
| C017180 | decamethrin | decamethrin results in increased activity of CYP2E1 protein | increases activity | 16494911 |
| C017180 | decamethrin | decamethrin results in increased expression of CYP2E1 mRNA | increases expression | 16859670 16494911 |
| C017180 | decamethrin | decamethrin results in increased expression of CYP2E1 protein | increases expression | 16859670 |
| C031071 | decanoic acid | [CYP2E1 protein co-treated with POR protein] results in increased hydroxylation of decanoic acid | affects cotreatment|increases hydroxylation | 2292581 |
| D003671 | DEET | CYP2E1 protein results in increased metabolism of DEET | increases metabolic processing | 11854147 |
| D003676 | Deferoxamine | Deferoxamine inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] | decreases reaction|increases reduction | 7710944 |
| D003891 | Desipramine | Desipramine results in decreased activity of CYP2E1 protein | decreases activity | 15135088 |
| D003907 | Dexamethasone | Dexamethasone results in decreased expression of CYP2E1 protein | decreases expression | 11181506 |
| D003907 | Dexamethasone | Dexamethasone results in increased expression of CYP2E1 protein | increases expression | 15965953 |
| C028009 | diallyl disulfide | diallyl disulfide results in decreased expression of CYP2E1 protein | decreases expression | 16000231 |
| C068327 | diallyl sulfone | diallyl sulfone inhibits the reaction [CYP2E1 protein results in decreased methylation of Dimethylnitrosamine] | decreases methylation|decreases reaction | 11181492 |
| C068327 | diallyl sulfone | diallyl sulfone inhibits the reaction [CYP2E1 protein results in increased metabolism of vinylidene chloride] | decreases reaction|increases metabolic processing | 10215634 |
| C068327 | diallyl sulfone | diallyl sulfone inhibits the reaction [CYP2E1 protein affects the oxidation of vinyl carbamate] | affects oxidation|decreases reaction | 17341656 |
| C068327 | diallyl sulfone | diallyl sulfone results in decreased activity of CYP2E1 protein | decreases activity | 17341656 |
| C068327 | diallyl sulfone | diallyl sulfone inhibits the reaction [CYP2E1 protein affects the oxidation of vinyl carbamate] | affects oxidation|decreases reaction | 17296623 |
| C068327 | diallyl sulfone | CYP2E1 affects the oxidation of diallyl sulfone | affects oxidation | 17341656 |
| D015946 | Ethylene Dibromide | CYP2E1 protein results in increased metabolism of Ethylene Dibromide | increases metabolic processing | 10841534 18350910 |
| C012279 | dibutylnitrosamine | [CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to dibutylnitrosamine | affects cotreatment|increases response to substance | 11733072 |
| C012279 | dibutylnitrosamine | [CYP2E1 protein co-treated with POR protein] results in increased susceptibility to dibutylnitrosamine | affects cotreatment|increases response to substance | 11035158 |
| C012279 | dibutylnitrosamine | CYP2E1 protein results in increased metabolism of dibutylnitrosamine | increases metabolic processing | 8625499 |
| D003994 | Bucladesine | Bucladesine promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol] | increases oxidation|increases reaction | 8531136 |
| D001728 | Dicumarol | Dicumarol promotes the reaction [CYP2E1 protein results in increased reduction of tirapazamine] | increases reaction|increases reduction | 7710944 |
| D004041 | Dietary Fats | Dietary Fats results in decreased expression of CYP2E1 mRNA | decreases expression | 18042831 |
| D004041 | Dietary Fats | [Dietary Fats co-treated with Diethylnitrosamine] results in increased expression of CYP2E1 protein | affects cotreatment|increases expression | 19551842 |
| D004041 | Dietary Fats | Dietary Fats results in increased expression of CYP2E1 protein | increases expression | 17967931 |
| D004041 | Dietary Fats | Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Diethylnitrosamine] results in increased expression of CYP2E1 protein] | affects cotreatment|decreases reaction|increases expression | 19551842 |
| D004052 | Diethylnitrosamine | CYB5 protein promotes the reaction [CYP2E1 protein results in increased activity of Diethylnitrosamine] | increases activity|increases reaction | 15728263 |
| D004052 | Diethylnitrosamine | CYP2E1 protein affects the metabolism of and results in increased activity of Diethylnitrosamine | affects metabolic processing|increases activity | 11774366 |
| D004052 | Diethylnitrosamine | CYP2E1 protein affects the metabolism of Diethylnitrosamine | affects metabolic processing | 2655891 |
| D004052 | Diethylnitrosamine | [CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to Diethylnitrosamine | affects cotreatment|increases response to substance | 11733072 |
| D004052 | Diethylnitrosamine | [CYP2E1 protein co-treated with POR protein] results in increased susceptibility to Diethylnitrosamine | affects cotreatment|increases response to substance | 11035158 |
| D004052 | Diethylnitrosamine | CYP2E1 protein results in increased activity of Diethylnitrosamine | increases activity | 15728263 |
| D004052 | Diethylnitrosamine | CYP2E1 protein results in increased susceptibility to Diethylnitrosamine | increases response to substance | 14669323 |
| D004052 | Diethylnitrosamine | CYP2E1 protein promotes the reaction [Diethylnitrosamine results in increased expression of BAX mRNA] | increases expression|increases reaction | 18056438 |
| D004052 | Diethylnitrosamine | CYP2E1 protein promotes the reaction [Diethylnitrosamine results in increased expression of CASP3 mRNA] | increases expression|increases reaction | 18056438 |
| D004052 | Diethylnitrosamine | CYP2E1 protein results in increased susceptibility to Diethylnitrosamine | increases response to substance | 18056438 |
| D004052 | Diethylnitrosamine | [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of CYP2E1 mRNA | affects cotreatment|decreases expression | 16158176 |
| D004052 | Diethylnitrosamine | [Dietary Fats co-treated with Diethylnitrosamine] results in increased expression of CYP2E1 protein | affects cotreatment|increases expression | 19551842 |
| D004052 | Diethylnitrosamine | [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of CYP2E1 mRNA | affects cotreatment|decreases expression | 14656948 |
| D004052 | Diethylnitrosamine | [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CYP2E1 protein | affects cotreatment|increases expression | 17393424 |
| D004052 | Diethylnitrosamine | [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP2E1 protein | affects cotreatment|increases expression | 16246485 |
| D004052 | Diethylnitrosamine | [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CYP2E1 mRNA | affects cotreatment|decreases expression | 20360939 |
| D004052 | Diethylnitrosamine | [Diethylnitrosamine co-treated with Cyclohexanols] results in increased expression of CYP2E1 protein | affects cotreatment|increases expression | 17393424 |
| D004052 | Diethylnitrosamine | [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP2E1 mRNA | affects cotreatment|decreases expression | 18544905 |
| D004052 | Diethylnitrosamine | Diethylnitrosamine results in decreased expression of CYP2E1 mRNA | decreases expression | 20360939 19638242 |
| D004052 | Diethylnitrosamine | Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Diethylnitrosamine] results in increased expression of CYP2E1 protein] | affects cotreatment|decreases reaction|increases expression | 19551842 |
| C035318 | diethylthiourea | diethylthiourea results in increased expression of CYP2E1 protein | increases expression | 10190572 |
| C039353 | dihydroxyethyldithiocarbamate | dihydroxyethyldithiocarbamate inhibits the reaction [CYP2E1 protein results in increased metabolism of chlorobenzene] | decreases reaction|increases metabolic processing | 9817075 |
| C039353 | dihydroxyethyldithiocarbamate | dihydroxyethyldithiocarbamate inhibits the reaction [[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene] | decreases reaction|increases activity|increases metabolic processing | 9817075 |
| C039353 | dihydroxyethyldithiocarbamate | dihydroxyethyldithiocarbamate inhibits the reaction [[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene] | decreases reaction|increases activity|increases metabolic processing | 9817075 |
| C039353 | dihydroxyethyldithiocarbamate | dihydroxyethyldithiocarbamate inhibits the reaction [[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of chlorobenzene] | decreases reaction|increases activity|increases metabolic processing | 9817075 |
| D004114 | Dimethadione | CYP2E1 protein results in decreased methylation of Dimethadione | decreases methylation | 8865369 |
| D004126 | Dimethylformamide | CYP2E1 protein polymorphism affects the metabolism of Dimethylformamide | affects metabolic processing | 11305777 |
| D004126 | Dimethylformamide | CYP2E1 protein results in increased metabolism of Dimethylformamide | increases metabolic processing | 9817075 |
| D004126 | Dimethylformamide | CYP2E1 protein results in increased oxidation of Dimethylformamide | increases oxidation | 10207612 |
| D004126 | Dimethylformamide | Dimethylformamide results in increased expression of CYP2E1 protein | increases expression | 10547960 |
| D004126 | Dimethylformamide | CYP2E1 protein affects the metabolism of Dimethylformamide | affects metabolic processing | 15772367 |
| D004128 | Dimethylnitrosamine | CYP2E1 protein affects the metabolism of and results in increased activity of Dimethylnitrosamine | affects metabolic processing|increases activity | 11600130 |
| D004128 | Dimethylnitrosamine | CYP2E1 protein affects the metabolism of Dimethylnitrosamine | affects metabolic processing | 2655891 16235733 |
| D004128 | Dimethylnitrosamine | [CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to Dimethylnitrosamine | affects cotreatment|increases response to substance | 11733072 |
| D004128 | Dimethylnitrosamine | CYP2E1 protein results in decreased methylation of Dimethylnitrosamine | decreases methylation | 11181492 |
| D004128 | Dimethylnitrosamine | CYP2E1 protein results in increased metabolism of and results in increased activity of Dimethylnitrosamine | increases activity|increases metabolic processing | 11960914 |
| D004128 | Dimethylnitrosamine | CYP2E1 protein results in increased metabolism of Dimethylnitrosamine | increases metabolic processing | 15242818 12464242 |
| D004128 | Dimethylnitrosamine | diallyl sulfone inhibits the reaction [CYP2E1 protein results in decreased methylation of Dimethylnitrosamine] | decreases methylation|decreases reaction | 11181492 |
| D004128 | Dimethylnitrosamine | Dimethylnitrosamine inhibits the reaction [Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]] | decreases reaction|increases oxidation | 8531136 |
| D004128 | Dimethylnitrosamine | Dimethylnitrosamine inhibits the reaction [Carbon Tetrachloride results in increased degradation of CYP2E1 protein] | decreases reaction|increases degradation | 8531136 |
| D004128 | Dimethylnitrosamine | Ethanol affects the reaction [CYP2E1 protein results in increased metabolism of Dimethylnitrosamine] | affects reaction|increases metabolic processing | 16235733 |
| D004128 | Dimethylnitrosamine | Ethanol promotes the reaction [CYP2E1 protein results in increased oxidation of Dimethylnitrosamine] | increases oxidation|increases reaction | 8074729 |
| D004128 | Dimethylnitrosamine | Lipopolysaccharides affects the reaction [CYP2E1 protein results in increased metabolism of Dimethylnitrosamine] | affects reaction|increases metabolic processing | 16235733 |
| D004128 | Dimethylnitrosamine | [vinyl carbamate co-treated with NADP] inhibits the reaction [CYP2E1 protein results in decreased methylation of Dimethylnitrosamine] | affects cotreatment|decreases methylation|decreases reaction | 11181492 |
| D004128 | Dimethylnitrosamine | Alloxan affects the reaction [CYP2E1 protein results in decreased methylation of Dimethylnitrosamine] | affects reaction|decreases methylation | 17034923 |
| D004128 | Dimethylnitrosamine | CYP2E1 protein affects the metabolism of Dimethylnitrosamine | affects metabolic processing | 15815077 |
| D004128 | Dimethylnitrosamine | [CYP2E1 protein co-treated with POR protein] results in decreased methylation of Dimethylnitrosamine | affects cotreatment|decreases methylation | 2292581 |
| D004128 | Dimethylnitrosamine | CYP2E1 protein results in decreased methylation of Dimethylnitrosamine | decreases methylation | 17034923 |
| D004128 | Dimethylnitrosamine | Dimethylnitrosamine binds to CYP2E1 protein | affects binding | 15815077 |
| D004128 | Dimethylnitrosamine | allyl sulfide inhibits the reaction [CYP2E1 protein results in increased metabolism of Dimethylnitrosamine] | decreases reaction|increases metabolic processing | 8117321 |
| D004128 | Dimethylnitrosamine | CYP2E1 protein results in decreased methylation of Dimethylnitrosamine | decreases methylation | 8194125 3113478 |
| D004128 | Dimethylnitrosamine | CYP2E1 protein results in increased metabolism of Dimethylnitrosamine | increases metabolic processing | 15763544 |
| D004128 | Dimethylnitrosamine | S-Adenosylmethionine inhibits the reaction [CYP2E1 protein results in increased metabolism of Dimethylnitrosamine] | decreases reaction|increases metabolic processing | 15763544 |
| D004128 | Dimethylnitrosamine | CYP2E1 protein results in increased metabolism of and results in increased activity of Dimethylnitrosamine | increases activity|increases metabolic processing | 16142352 |
| D004121 | Dimethyl Sulfoxide | Dimethyl Sulfoxide affects the expression of CYP2E1 mRNA | affects expression | 12843640 |
| D004121 | Dimethyl Sulfoxide | Dimethyl Sulfoxide inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] | decreases reaction|increases degradation | 9143349 |
| D004121 | Dimethyl Sulfoxide | Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein promotes the reaction [pyridine results in increased expression of CYP1A1 mRNA]] | decreases reaction|increases expression|increases reaction | 12147272 |
| D004121 | Dimethyl Sulfoxide | Dimethyl Sulfoxide results in increased expression of CYP2E1 protein | increases expression | 8074729 |
| D004121 | Dimethyl Sulfoxide | Dimethyl Sulfoxide results in increased activity of CYP2E1 protein | increases activity | 17177172 |
| D004121 | Dimethyl Sulfoxide | Dimethyl Sulfoxide binds to and results in increased expression of CYP2E1 protein | affects binding|increases expression | 3337723 |
| D004121 | Dimethyl Sulfoxide | Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein results in increased metabolism of methylformamide] | decreases reaction|increases metabolic processing | 1538706 |
| D004121 | Dimethyl Sulfoxide | Dimethyl Sulfoxide results in increased expression of CYP2E1 protein | increases expression | 3113478 |
| D004221 | Disulfiram | Disulfiram inhibits the reaction [CYP2E1 protein results in increased oxidation of Halothane] | decreases reaction|increases oxidation | 10805064 |
| D004221 | Disulfiram | Disulfiram binds to and results in decreased activity of CYP2E1 protein | affects binding|decreases activity | 18754103 |
| D004221 | Disulfiram | Disulfiram results in decreased activity of CYP2E1 protein | decreases activity | 9393675 |
| D004221 | Disulfiram | Disulfiram results in decreased expression of CYP2E1 mRNA | decreases expression | 9393675 |
| D004221 | Disulfiram | Disulfiram results in decreased expression of CYP2E1 protein | decreases expression | 9393675 |
| D004221 | Disulfiram | Disulfiram inhibits the reaction [4-xylene results in increased activity of CYP2E1 protein] | decreases reaction|increases activity | 12781212 |
| D004221 | Disulfiram | Disulfiram inhibits the reaction [Toluene results in increased activity of CYP2E1 protein] | decreases reaction|increases activity | 12781212 |
| D004050 | Ditiocarb | Ditiocarb inhibits the reaction [CYP2E1 protein affects the metabolism of Toluene] | affects metabolic processing|decreases reaction | 8592870 |
| D004050 | Ditiocarb | Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of 2-xylene] | decreases reaction|increases metabolic processing | 8558417 |
| D004050 | Ditiocarb | Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of 3-xylene] | decreases reaction|increases metabolic processing | 8558417 |
| D004050 | Ditiocarb | Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-xylene] | decreases reaction|increases metabolic processing | 8558417 |
| D004050 | Ditiocarb | Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of Theobromine] | decreases reaction|increases metabolic processing | 10215755 |
| D004050 | Ditiocarb | Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of Toluene] | decreases reaction|increases metabolic processing | 8558417 |
| D004050 | Ditiocarb | Ditiocarb results in decreased activity of CYP2E1 protein | decreases activity | 15306208 8819299 |
| D004050 | Ditiocarb | [Ditiocarb co-treated with CYP2E1 gene mutant form] results in decreased metabolism of Styrene | affects cotreatment|decreases metabolic processing | 12746132 |
| D004050 | Ditiocarb | Ditiocarb inhibits the reaction [CYP2E1 protein results in increased hydroxylation of 4-nitrophenol] | decreases reaction|increases hydroxylation | 9618253 |
| D004050 | Ditiocarb | Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of methylformamide] | decreases reaction|increases metabolic processing | 1538706 |
| D004050 | Ditiocarb | Ditiocarb inhibits the reaction [pyridine results in increased activity of CYP2E1 protein] | decreases reaction|increases activity | 9618253 |
| D004050 | Ditiocarb | Ditiocarb results in decreased activity of CYP2E1 protein | decreases activity | 1356728 |
| D004050 | Ditiocarb | Ditiocarb results in decreased activity of CYP2E1 | decreases activity | 10910959 |
| D004281 | Docosahexaenoic Acids | Docosahexaenoic Acids results in decreased activity of CYP2E1 protein | decreases activity | 16978661 |
| D004365 | Drugs, Chinese Herbal | Drugs, Chinese Herbal results in decreased expression of CYP2E1 mRNA | decreases expression | 15706880 |
| C042986 | ebselen | ebselen inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 mRNA] | decreases reaction|increases expression | 11903743 |
| D004492 | Edetic Acid | Edetic Acid inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] | decreases reaction|increases degradation | 9143349 |
| D004533 | Egtazic Acid | Egtazic Acid inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] | decreases reaction|increases degradation | 9143349 |
| D015118 | Eicosapentaenoic Acid | Eicosapentaenoic Acid results in decreased activity of CYP2E1 protein | decreases activity | 16978661 |
| C105196 | enfuvirtide | enfuvirtide affects the activity of CYP2E1 protein | affects activity | 15656696 |
| C045651 | epigallocatechin gallate | epigallocatechin gallate results in increased expression of and results in increased activity of CYP2E1 protein | increases activity|increases expression | 14600287 |
| C091891 | epsilon-viniferin | epsilon-viniferin results in decreased activity of CYP2E1 protein | decreases activity | 12818727 |
| C007366 | erythritol anhydride | CYP2E1 gene polymorphism affects the susceptibility to erythritol anhydride | affects response to substance | 15036125 |
| C007366 | erythritol anhydride | CYP2E1 gene polymorphism results in increased susceptibility to erythritol anhydride | increases response to substance | 17078101 |
| D004958 | Estradiol | Estradiol results in decreased expression of CYP2E1 mRNA | decreases expression | 20106945 |
| D004967 | Estrogens | Estrogens results in decreased expression of CYP2E1 protein | decreases expression | 2785912 |
| D000431 | Ethanol | Ethanol results in increased activity of CYP2E1 protein | increases activity | 12451447 |
| D000431 | Ethanol | [Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein | affects cotreatment|increases expression | 17034788 |
| D000431 | Ethanol | [[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT18 protein | affects cotreatment|increases expression | 17034788 |
| D000431 | Ethanol | [[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT8 protein | affects cotreatment|increases expression | 17034788 |
| D000431 | Ethanol | CYP2E1 protein results in increased metabolism of Ethanol | increases metabolic processing | 10826103 18845238 12464242 10573527 |
| D000431 | Ethanol | [CYP2E1 protein results in increased metabolism of Ethanol] which results in decreased abundance of Glutathione | decreases abundance|increases metabolic processing | 10573527 |
| D000431 | Ethanol | [CYP2E1 protein results in increased metabolism of Ethanol] which results in increased abundance of Acetaldehyde | increases abundance|increases metabolic processing | 18845238 |
| D000431 | Ethanol | [CYP2E1 protein results in increased metabolism of Ethanol] which results in increased abundance of Nitric Oxide | increases abundance|increases metabolic processing | 18845238 |
| D000431 | Ethanol | [CYP2E1 protein results in increased metabolism of Ethanol] which results in increased abundance of Reactive Oxygen Species | increases abundance|increases metabolic processing | 18845238 |
| D000431 | Ethanol | CYP2E1 protein results in increased susceptibility to Ethanol | increases response to substance | 8798623 |
| D000431 | Ethanol | Ethanol affects the reaction [CYP2E1 protein results in increased metabolism of Dimethylnitrosamine] | affects reaction|increases metabolic processing | 16235733 |
| D000431 | Ethanol | Ethanol affects the reaction [CYP2E1 protein results in increased susceptibility to Acetaminophen] | affects reaction|increases response to substance | 11212141 |
| D000431 | Ethanol | Ethanol inhibits the reaction [Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]] | decreases reaction|increases oxidation | 8531136 |
| D000431 | Ethanol | Ethanol inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] | decreases reaction|increases degradation | 9143349 |
| D000431 | Ethanol | Ethanol promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol] | increases oxidation|increases reaction | 8531136 8074729 |
| D000431 | Ethanol | Ethanol promotes the reaction [CYP2E1 protein results in increased oxidation of aniline] | increases oxidation|increases reaction | 8074729 |
| D000431 | Ethanol | Ethanol promotes the reaction [CYP2E1 protein results in increased oxidation of Dimethylnitrosamine] | increases oxidation|increases reaction | 8074729 |
| D000431 | Ethanol | Ethanol results in increased activity of CYP2E1 protein | increases activity | 8074729 11212141 |
| D000431 | Ethanol | Ethanol results in increased expression of and results in increased activity of CYP2E1 protein | increases activity|increases expression | 18845238 15802389 |
| D000431 | Ethanol | Ethanol results in increased expression of CYP2E1 protein | increases expression | 17590308 8074729 3782137 |
| D000431 | Ethanol | fomepizole inhibits the reaction [[CYP2E1 protein results in increased metabolism of Ethanol] which results in increased abundance of Reactive Oxygen Species] | decreases reaction|increases abundance|increases metabolic processing | 18845238 |
| D000431 | Ethanol | Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased susceptibility to Ethanol] | increases reaction|increases response to substance | 8798623 |
| D000431 | Ethanol | Ethanol results in increased activity of CYP2E1 protein | increases activity | 15920153 10667633 |
| D000431 | Ethanol | Ethanol results in increased expression of CYP2E1 protein | increases expression | 15920153 11515535 |
| D000431 | Ethanol | [Urethane co-treated with Ethanol] results in increased activity of CYP2E1 protein | affects cotreatment|increases activity | 15582191 |
| D000431 | Ethanol | Zinc Sulfate inhibits the reaction [Ethanol results in increased activity of CYP2E1 protein] | decreases reaction|increases activity | 15920153 |
| D000431 | Ethanol | Zinc Sulfate inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein] | decreases reaction|increases expression | 15920153 |
| D000431 | Ethanol | Carnitine promotes the reaction [Ethanol results in increased expression of CYP2E1 protein] | increases expression|increases reaction | 8130774 |
| D000431 | Ethanol | CYP2E1 protein results in increased metabolism of Ethanol | increases metabolic processing | 11147839 7562599 15763544 |
| D000431 | Ethanol | [CYP2E1 protein results in increased metabolism of Ethanol] which results in increased chemical synthesis of Acetaldehyde | increases chemical synthesis|increases metabolic processing | 7562599 |
| D000431 | Ethanol | Ethanol affects the activity of CYP2E1 protein | affects activity | 17533807 |
| D000431 | Ethanol | Ethanol binds to and results in increased expression of CYP2E1 protein | affects binding|increases expression | 3337723 |
| D000431 | Ethanol | [Ethanol co-treated with nitrosobenzylmethylamine] results in increased expression of CYP2E1 protein | affects cotreatment|increases expression | 16704527 |
| D000431 | Ethanol | Ethanol inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] | decreases reaction|increases reduction | 7710944 |
| D000431 | Ethanol | Ethanol promotes the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol] | increases metabolic processing|increases reaction | 7601153 |
| D000431 | Ethanol | Ethanol promotes the reaction [CYP2E1 protein results in increased metabolism of Carbon Tetrachloride] | increases metabolic processing|increases reaction | 7601153 |
| D000431 | Ethanol | Ethanol results in increased activity of CYP2E1 protein | increases activity | 15998439 |
| D000431 | Ethanol | Ethanol results in increased expression of and results in increased activity of CYP2E1 protein | increases activity|increases expression | 15946133 |
| D000431 | Ethanol | Ethanol results in increased expression of CYP2E1 mRNA | increases expression | 7562599 8130774 |
| D000431 | Ethanol | Ethanol results in increased expression of CYP2E1 protein | increases expression | 7587954 8130774 7601153 3113478 9884160 3782137 7562599 |
| D000431 | Ethanol | phenethyl isothiocyanate inhibits the reaction [[CYP2E1 protein results in increased metabolism of Ethanol] which results in increased chemical synthesis of Acetaldehyde] | decreases reaction|increases chemical synthesis|increases metabolic processing | 7562599 |
| D000431 | Ethanol | phenethyl isothiocyanate inhibits the reaction [Ethanol results in increased expression of CYP2E1 mRNA] | decreases reaction|increases expression | 7562599 |
| D000431 | Ethanol | phenethyl isothiocyanate inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein] | decreases reaction|increases expression | 7562599 |
| D000431 | Ethanol | S-Adenosylmethionine inhibits the reaction [CYP2E1 protein results in increased metabolism of Ethanol] | decreases reaction|increases metabolic processing | 15763544 |
| D000431 | Ethanol | CYP2E1 protein results in increased metabolism of Ethanol | increases metabolic processing | 16737972 16470306 |
| D000431 | Ethanol | Ethanol promotes the reaction [CYP2E1 protein results in increased metabolism of Tretinoin] | increases metabolic processing|increases reaction | 16054987 |
| D000431 | Ethanol | Ethanol promotes the reaction [CYP2E1 protein results in increased metabolism of Vitamin A] | increases metabolic processing|increases reaction | 16054987 |
| D000431 | Ethanol | Ethanol results in decreased activity of CYP2E1 protein | decreases activity | 7710944 |
| D000431 | Ethanol | Ethanol results in increased expression of CYP2E1 protein | increases expression | 16054987 |
| C004912 | ethylbenzene | ethylbenzene results in increased expression of and results in increased activity of CYP2E1 protein | increases activity|increases expression | 11884239 |
| C004912 | ethylbenzene | ethylbenzene results in increased expression of CYP2E1 mRNA | increases expression | 11884239 |
| C004912 | ethylbenzene | ethylbenzene results in increased expression of CYP2E1 protein | increases expression | 1417939 |
| C004912 | ethylbenzene | GH1 protein inhibits the reaction [ethylbenzene results in increased expression of CYP2E1 protein] | decreases reaction|increases expression | 11884239 |
| C036216 | ethylene | ethylene results in decreased activity of CYP2E1 protein | decreases activity | 15141094 |
| C025475 | ethylene bromohydrin | CYP2E1 protein results in increased metabolism of ethylene bromohydrin | increases metabolic processing | 8861782 |
| D005204 | Farnesol | Farnesol results in increased activity of CYP2E1 protein | increases activity | 15840382 |
| C033789 | fenarimol | [fenarimol co-treated with acephate] affects the expression of CYP2E1 protein | affects cotreatment|affects expression | 17686559 |
| C033789 | fenarimol | [fenarimol co-treated with vinclozolin] affects the expression of CYP2E1 protein | affects cotreatment|affects expression | 17686559 |
| C033789 | fenarimol | [fenarimol co-treated with vinclozolin co-treated with acephate] affects the expression of CYP2E1 protein | affects cotreatment|affects expression | 17686559 |
| C045858 | ferric-adenosine triphosphate complex | ferric-adenosine triphosphate complex inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol] | decreases reaction|increases oxidation | 8531136 |
| C045858 | ferric-adenosine triphosphate complex | ferric-adenosine triphosphate complex results in increased degradation of CYP2E1 protein | increases degradation | 8531136 |
| C020326 | ferric nitrilotriacetate | [Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein | affects cotreatment|increases expression | 17034788 |
| C020326 | ferric nitrilotriacetate | [[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT18 protein | affects cotreatment|increases expression | 17034788 |
| C020326 | ferric nitrilotriacetate | [[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT8 protein | affects cotreatment|increases expression | 17034788 |
| D015073 | 2-Acetylaminofluorene | 2-Acetylaminofluorene analog results in increased expression of CYP2E1 protein | increases expression | 15916741 |
| D015073 | 2-Acetylaminofluorene | [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of CYP2E1 mRNA | affects cotreatment|decreases expression | 16158176 |
| D015073 | 2-Acetylaminofluorene | 2-Acetylaminofluorene results in increased expression of CYP2E1 protein | increases expression | 15916741 |
| D015073 | 2-Acetylaminofluorene | [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of CYP2E1 mRNA | affects cotreatment|decreases expression | 14656948 |
| D015073 | 2-Acetylaminofluorene | [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CYP2E1 protein | affects cotreatment|increases expression | 17393424 |
| D005476 | Fluphenazine | Fluphenazine results in decreased activity of CYP2E1 protein | decreases activity | 15135088 |
| C010238 | fomepizole | fomepizole inhibits the reaction [CYP2E1 protein affects the metabolism of Toluene] | affects metabolic processing|decreases reaction | 8592870 |
| C010238 | fomepizole | fomepizole inhibits the reaction [Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]] | decreases reaction|increases oxidation | 8531136 |
| C010238 | fomepizole | fomepizole inhibits the reaction [Carbon Tetrachloride results in increased degradation of CYP2E1 protein] | decreases reaction|increases degradation | 8531136 |
| C010238 | fomepizole | fomepizole inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] | decreases reaction|increases degradation | 9143349 |
| C010238 | fomepizole | fomepizole inhibits the reaction [CYP2E1 protein affects the metabolism of 2,6-xylidine metabolite] | affects metabolic processing|decreases reaction | 11409937 |
| C010238 | fomepizole | fomepizole inhibits the reaction [[CYP2E1 protein results in increased metabolism of Ethanol] which results in increased abundance of Reactive Oxygen Species] | decreases reaction|increases abundance|increases metabolic processing | 18845238 |
| C010238 | fomepizole | fomepizole results in increased expression of CYP2E1 protein | increases expression | 8074729 |
| C010238 | fomepizole | fomepizole promotes the reaction [CYP2E1 protein results in increased metabolism of methylformamide] | increases metabolic processing|increases reaction | 1538706 |
| C010238 | fomepizole | fomepizole results in increased activity of CYP2E1 protein | increases activity | 3782137 |
| C010238 | fomepizole | fomepizole results in increased expression of CYP2E1 protein | increases expression | 3113478 3782137 |
| C010238 | fomepizole | fomepizole results in decreased activity of CYP2E1 protein | decreases activity | 10828259 16737972 |
| D005503 | Food Additives | Food Additives results in increased expression of CYP2E1 mRNA | increases expression | 18803703 |
| D005579 | Fossil Fuels | Fossil Fuels results in increased expression of CYP2E1 protein | increases expression | 14961354 |
| C056933 | fumonisin B1 | fumonisin B1 results in decreased expression of CYP2E1 mRNA | decreases expression | 16221962 |
| C050131 | furafylline | furafylline results in decreased activity of CYP2E1 protein | decreases activity | 15879494 |
| C039281 | furan | furan results in decreased expression of CYP2E1 mRNA | decreases expression | 15120968 |
| C038958 | gadolinium chloride | gadolinium chloride inhibits the reaction [Styrene results in increased expression of CYP2E1 mRNA] | decreases reaction|increases expression | 18202523 |
| C038958 | gadolinium chloride | gadolinium chloride inhibits the reaction [Styrene results in increased expression of CYP2E1 protein] | decreases reaction|increases expression | 18202523 |
| D005742 | Gasoline | Gasoline results in increased expression of CYP2E1 protein | increases expression | 14961354 |
| C063170 | Ginkgo biloba extract 761 | Ginkgo biloba extract 761 results in decreased activity of CYP2E1 protein | decreases activity | 15147983 |
| C063170 | Ginkgo biloba extract 761 | Ginkgo biloba extract 761 results in increased expression of and results in increased activity of CYP2E1 protein | increases activity|increases expression | 18421621 |
| D005978 | Glutathione | [CYP2E1 protein results in increased metabolism of Ethanol] which results in decreased abundance of Glutathione | decreases abundance|increases metabolic processing | 10573527 |
| D005978 | Glutathione | Glutathione inhibits the reaction [CYP2E1 protein results in increased susceptibility to Styrene] | decreases reaction|increases response to substance | 16872732 |
| D005990 | Glycerol | Glycerol inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] | decreases reaction|increases degradation | 9143349 |
| C511402 | Grape Seed Proanthocyanidins | Grape Seed Proanthocyanidins results in decreased activity of CYP2E1 protein | decreases activity | 12587719 |
| C511402 | Grape Seed Proanthocyanidins | CYP2E1 protein results in increased metabolism of Grape Seed Proanthocyanidins | increases metabolic processing | 11330834 |
| C511402 | Grape Seed Proanthocyanidins | Grape Seed Proanthocyanidins results in decreased activity of CYP2E1 protein | decreases activity | 11330834 |
| C511402 | Grape Seed Proanthocyanidins | CYP2E1 protein results in increased metabolism of Grape Seed Proanthocyanidins | increases metabolic processing | 11330834 |
| C511402 | Grape Seed Proanthocyanidins | Grape Seed Proanthocyanidins results in decreased activity of CYP2E1 protein | decreases activity | 11330834 |
| C511402 | Grape Seed Proanthocyanidins | [Grape Seed Proanthocyanidins results in decreased activity of CYP2E1 protein] which results in decreased hydroxylation of aniline | decreases activity|decreases hydroxylation | 11330834 |
| D006221 | Halothane | CYP2E1 protein results in increased metabolism of Halothane | increases metabolic processing | 11684365 12464242 |
| D006221 | Halothane | CYP2E1 protein results in increased oxidation of Halothane | increases oxidation | 10805064 |
| D006221 | Halothane | Disulfiram inhibits the reaction [CYP2E1 protein results in increased oxidation of Halothane] | decreases reaction|increases oxidation | 10805064 |
| D006581 | Hexachlorobenzene | Hexachlorobenzene results in decreased expression of CYP2E1 mRNA | decreases expression | 15159207 |
| D006581 | Hexachlorobenzene | Hexachlorobenzene results in increased expression of CYP2E1 protein | increases expression | 10696772 |
| C022870 | HI 6 | HI 6 results in decreased activity of CYP2E1 protein | decreases activity | 19539805 |
| C029424 | hydrazine | hydrazine results in increased activity of CYP2E1 protein | increases activity | 15132840 |
| D047348 | Hydrolyzable Tannins | Hydrolyzable Tannins results in decreased activity of CYP2E1 protein | decreases activity | 12749824 |
| D047348 | Hydrolyzable Tannins | Hydrolyzable Tannins results in decreased expression of CYP2E1 protein | decreases expression | 12749824 |
| C029899 | imidazole | imidazole results in increased expression of CYP2E1 protein | increases expression | 3337723 |
| D007213 | Indomethacin | Indomethacin results in decreased expression of CYP2E1 mRNA | decreases expression | 16771604 |
| D007510 | Isatin | Isatin results in increased expression of CYP2E1 mRNA | increases expression | 15056799 |
| D007538 | Isoniazid | CYP2E1 gene polymorphism affects the susceptibility to Isoniazid | affects response to substance | 12668988 |
| D007538 | Isoniazid | CYP2E1 gene SNP affects the susceptibility to Isoniazid | affects response to substance | 20485159 |
| D007538 | Isoniazid | CYP2E1 protein results in increased metabolism of Isoniazid | increases metabolic processing | 17950035 |
| D007538 | Isoniazid | Isoniazid results in increased expression of CYP2E1 protein | increases expression | 8074729 |
| D007538 | Isoniazid | 2-(allylthio)pyrazine inhibits the reaction [Isoniazid results in increased expression of CYP2E1 protein] | decreases reaction|increases expression | 9065729 |
| D007538 | Isoniazid | Isoniazid inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] | decreases reaction|increases reduction | 7710944 |
| D007538 | Isoniazid | Isoniazid results in increased activity of CYP2E1 protein | increases activity | 9129171 9051121 15205388 12458634 15132840 |
| D007538 | Isoniazid | [Isoniazid results in increased activity of CYP2E1 protein] which results in increased metabolism of 4-dichlorobenzene | increases activity|increases metabolic processing | 9051121 |
| D007538 | Isoniazid | Isoniazid results in increased expression of and results in increased activity of CYP2E1 protein | increases activity|increases expression | 18754103 |
| D007538 | Isoniazid | Isoniazid results in increased expression of CYP2E1 mRNA | increases expression | 11752103 |
| D007538 | Isoniazid | Isoniazid results in increased expression of CYP2E1 protein | increases expression | 3113478 15205388 15763544 9065729 |
| D007538 | Isoniazid | Rifampin inhibits the reaction [Isoniazid results in increased expression of CYP2E1 protein] | decreases reaction|increases expression | 15132840 |
| D007538 | Isoniazid | Thiram inhibits the reaction [Isoniazid results in increased activity of CYP2E1 protein] | decreases reaction|increases activity | 12458634 |
| D007538 | Isoniazid | Isoniazid results in decreased activity of CYP2E1 protein | decreases activity | 7710944 |
| D007538 | Isoniazid | Isoniazid results in increased expression of CYP2E1 | increases expression | 15890479 |
| C053401 | kahweol | kahweol results in decreased activity of CYP2E1 protein | decreases activity | 17590492 |
| D007649 | Ketamine | Ketamine results in increased expression of CYP2E1 protein | increases expression | 16076768 |
| D007654 | Ketoconazole | Ketoconazole results in decreased activity of CYP2E1 protein | decreases activity | 15618748 |
| C011890 | kojic acid | [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP2E1 mRNA | affects cotreatment|decreases expression | 18544905 |
| D007848 | Laurates | [CYP2E1 protein co-treated with POR protein] results in increased hydroxylation of Laurates | affects cotreatment|increases hydroxylation | 2292581 |
| C030358 | lauric acid | CYP2E1 protein results in increased metabolism of lauric acid | increases metabolic processing | 12464242 |
| C032854 | leupeptin | leupeptin inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] | decreases reaction|increases degradation | 9143349 |
| D001556 | Lindane | Lindane results in increased activity of CYP2E1 protein | increases activity | 14631868 12842176 |
| D001556 | Lindane | Lindane results in increased expression of CYP2E1 protein | increases expression | 14631868 12842176 |
| D008070 | Lipopolysaccharides | Lipopolysaccharides affects the reaction [CYP2E1 protein results in increased metabolism of Dimethylnitrosamine] | affects reaction|increases metabolic processing | 16235733 |
| D008344 | Maneb | [Maneb co-treated with Paraquat] results in increased expression of CYP2E1 mRNA | affects cotreatment|increases expression | 16510128 |
| D008344 | Maneb | Maneb results in decreased activity of CYP2E1 protein | decreases activity | 11043497 |
| C013592 | mangiferin | mangiferin results in decreased activity of CYP2E1 protein | decreases activity | 18053976 |
| C008385 | methacrylonitrile | CYP2E1 protein results in increased metabolism of methacrylonitrile | increases metabolic processing | 10215687 |
| C008385 | methacrylonitrile | [CYP2E1 protein results in increased metabolism of methacrylonitrile] which results in increased abundance of Cyanides | increases abundance|increases metabolic processing | 15893539 |
| C008385 | methacrylonitrile | methacrylonitrile results in increased activity of CYP2E1 protein | increases activity | 11939710 |
| C008385 | methacrylonitrile | methacrylonitrile results in increased expression of CYP2E1 mRNA | increases expression | 11939710 |
| C008385 | methacrylonitrile | methacrylonitrile results in increased expression of CYP2E1 protein | increases expression | 11939710 |
| D008694 | Methamphetamine | CYP2E1 protein affects the metabolism of Methamphetamine metabolite | affects metabolic processing | 16038959 |
| D008731 | Methoxychlor | Methoxychlor results in increased expression of and results in increased activity of CYP2E1 protein | increases activity|increases expression | 12919727 |
| D008730 | Methoxsalen | Methoxsalen results in decreased activity of CYP2E1 protein | decreases activity | 15879494 |
| D008748 | Methylcholanthrene | [Acetone co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 mRNA | affects cotreatment|decreases expression | 8734847 |
| D008748 | Methylcholanthrene | [Acetone co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 protein | affects cotreatment|decreases expression | 8734847 |
| D008748 | Methylcholanthrene | [Acetone co-treated with Methylcholanthrene] results in increased activity of CYP2E1 protein | affects cotreatment|increases activity | 8734847 |
| D008748 | Methylcholanthrene | [Acetone co-treated with Methylcholanthrene] results in increased expression of CYP2E1 protein | affects cotreatment|increases expression | 8734847 |
| D008748 | Methylcholanthrene | Methylcholanthrene results in decreased activity of CYP2E1 protein | decreases activity | 8734847 |
| D008748 | Methylcholanthrene | Methylcholanthrene results in decreased expression of CYP2E1 mRNA | decreases expression | 8734847 7493548 |
| D008748 | Methylcholanthrene | Methylcholanthrene results in decreased expression of CYP2E1 protein | decreases expression | 8734847 3113478 |
| D008748 | Methylcholanthrene | Methylcholanthrene results in increased expression of CYP2E1 mRNA | increases expression | 19889059 |
| D008748 | Methylcholanthrene | Methylcholanthrene results in increased expression of CYP2E1 protein | increases expression | 19889059 |
| D008748 | Methylcholanthrene | [protocatechuic acid co-treated with Methylcholanthrene] results in decreased activity of CYP2E1 protein | affects cotreatment|decreases activity | 15302093 |
| D008748 | Methylcholanthrene | [pyridine co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 mRNA | affects cotreatment|decreases expression | 8734847 |
| D008748 | Methylcholanthrene | [pyridine co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 protein | affects cotreatment|decreases expression | 8734847 |
| D008748 | Methylcholanthrene | [pyridine co-treated with Methylcholanthrene] results in increased activity of CYP2E1 protein | affects cotreatment|increases activity | 8734847 |
| D008748 | Methylcholanthrene | [pyridine co-treated with Methylcholanthrene] results in increased expression of CYP2E1 protein | affects cotreatment|increases expression | 8734847 |
| D008752 | Methylene Chloride | 3-xylene promotes the reaction [CYP2E1 protein results in increased metabolism of Methylene Chloride] | increases metabolic processing|increases reaction | 8889796 |
| D008752 | Methylene Chloride | Benzene promotes the reaction [CYP2E1 protein results in increased metabolism of Methylene Chloride] | increases metabolic processing|increases reaction | 8889796 |
| D008752 | Methylene Chloride | CYP2E1 protein results in increased metabolism of Methylene Chloride | increases metabolic processing | 8889796 |
| D008752 | Methylene Chloride | Toluene promotes the reaction [CYP2E1 protein results in increased metabolism of Methylene Chloride] | increases metabolic processing|increases reaction | 8889796 |
| C017510 | methylethylnitrosamine | CYP2E1 protein affects the metabolism of and results in increased activity of methylethylnitrosamine | affects metabolic processing|increases activity | 11600130 |
| C002950 | methylformamide | CYP2E1 protein results in increased metabolism of methylformamide | increases metabolic processing | 1538706 |
| C002950 | methylformamide | 4-nitrophenol inhibits the reaction [CYP2E1 protein results in increased metabolism of methylformamide] | decreases reaction|increases metabolic processing | 1538706 |
| C002950 | methylformamide | CYP2E1 protein results in increased metabolism of methylformamide | increases metabolic processing | 1538706 |
| C002950 | methylformamide | Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein results in increased metabolism of methylformamide] | decreases reaction|increases metabolic processing | 1538706 |
| C002950 | methylformamide | Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of methylformamide] | decreases reaction|increases metabolic processing | 1538706 |
| C002950 | methylformamide | fomepizole promotes the reaction [CYP2E1 protein results in increased metabolism of methylformamide] | increases metabolic processing|increases reaction | 1538706 |
| D008874 | Midazolam | CYP2E1 protein results in increased metabolism of Midazolam | increases metabolic processing | 17590308 |
| D008917 | Mirex | Mirex results in decreased expression of CYP2E1 protein | decreases expression | 3113478 |
| D015058 | 1-Naphthylisothiocyanate | 1-Naphthylisothiocyanate results in decreased expression of CYP2E1 mRNA | decreases expression | 15913567 |
| C026385 | n-hexane | CYP2E1 gene polymorphism affects the susceptibility to n-hexane | affects response to substance | 16484137 |
| C026385 | n-hexane | CYP2E1 protein results in increased hydroxylation of n-hexane | increases hydroxylation | 16484137 |
| C026385 | n-hexane | CYP2E1 protein results in increased metabolism of n-hexane | increases metabolic processing | 11201664 |
| D009538 | Nicotine | Nicotine results in increased expression of CYP2E1 protein | increases expression | 16368115 |
| D009538 | Nicotine | Nicotine results in increased expression of CYP2E1 protein | increases expression | 16434548 |
| D009569 | Nitric Oxide | [CYP2E1 protein results in increased metabolism of Ethanol] which results in increased abundance of Nitric Oxide | increases abundance|increases metabolic processing | 18845238 |
| D005996 | Nitroglycerin | Nitroglycerin results in increased expression of CYP2E1 mRNA | increases expression | 12102619 |
| D009602 | Nitrosamines | [CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to Nitrosamines | affects cotreatment|increases response to substance | 11733072 |
| D009602 | Nitrosamines | CYP2E1 protein results in increased metabolism of and results in increased activity of Nitrosamines | increases activity|increases metabolic processing | 16470306 |
| C014707 | nitrosobenzylmethylamine | CYP2E1 protein affects the metabolism of nitrosobenzylmethylamine | affects metabolic processing | 2655891 |
| C014707 | nitrosobenzylmethylamine | [Ethanol co-treated with nitrosobenzylmethylamine] results in increased expression of CYP2E1 protein | affects cotreatment|increases expression | 16704527 |
| D009242 | N-Nitrosopyrrolidine | CYP2E1 protein affects the metabolism of and results in increased activity of N-Nitrosopyrrolidine | affects metabolic processing|increases activity | 11774366 |
| C468271 | N-methyl-N-benzylnitrosamine | N-methyl-N-benzylnitrosamine results in decreased activity of CYP2E1 protein | decreases activity | 12222751 |
| C014102 | N-methyl-N-nitrosoaniline | CYP2E1 protein affects the metabolism of N-methyl-N-nitrosoaniline | affects metabolic processing | 15815077 |
| C014102 | N-methyl-N-nitrosoaniline | N-methyl-N-nitrosoaniline binds to CYP2E1 protein | affects binding | 15815077 |
| C454677 | N,N-diethyl-3-hydroxymethylbenzamide | CYP2E1 protein results in increased chemical synthesis of N,N-diethyl-3-hydroxymethylbenzamide | increases chemical synthesis | 11854147 |
| C014129 | N-nitrosodiethanolamine | CYP2E1 protein results in increased metabolism of N-nitrosodiethanolamine | increases metabolic processing | 18616954 |
| C013161 | N-nitroso(di-n-propyl)amine | CYB5 protein promotes the reaction [CYP2E1 protein results in increased activity of N-nitroso(di-n-propyl)amine] | increases activity|increases reaction | 15728263 |
| C013161 | N-nitroso(di-n-propyl)amine | CYP2E1 protein affects the metabolism of N-nitroso(di-n-propyl)amine | affects metabolic processing | 10910959 |
| C013161 | N-nitroso(di-n-propyl)amine | [CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to N-nitroso(di-n-propyl)amine | affects cotreatment|increases response to substance | 11733072 |
| C013161 | N-nitroso(di-n-propyl)amine | [CYP2E1 protein co-treated with POR protein] results in increased susceptibility to N-nitroso(di-n-propyl)amine | affects cotreatment|increases response to substance | 11035158 |
| C013161 | N-nitroso(di-n-propyl)amine | CYP2E1 protein results in increased activity of N-nitroso(di-n-propyl)amine | increases activity | 15728263 |
| C013161 | N-nitroso(di-n-propyl)amine | CYP2E1 protein affects the metabolism of N-nitroso(di-n-propyl)amine | affects metabolic processing | 10910959 |
| C013161 | N-nitroso(di-n-propyl)amine | CYP2E1 protein results in decreased nitrosation of N-nitroso(di-n-propyl)amine | decreases nitrosation | 10910959 |
| C013161 | N-nitroso(di-n-propyl)amine | CYP2E1 protein results in increased metabolism of N-nitroso(di-n-propyl)amine | increases metabolic processing | 8625499 |
| C002741 | N-nitrosomorpholine | CYP2E1 protein affects the metabolism of and results in increased activity of N-nitrosomorpholine | affects metabolic processing|increases activity | 11774366 |
| C002743 | N-nitrosopiperidine | CYP2E1 protein affects the metabolism of and results in increased activity of N-nitrosopiperidine | affects metabolic processing|increases activity | 11774366 |
| C093285 | NOC 18 | NOC 18 inhibits the reaction [Phenytoin results in increased expression of CYP2E1 mRNA] | decreases reaction|increases expression | 18206661 |
| C063006 | norflurane | 4-nitrophenol inhibits the reaction [CYP2E1 protein results in increased oxidation of norflurane] | decreases reaction|increases oxidation | 1356728 |
| C063006 | norflurane | CYP2E1 protein results in increased oxidation of norflurane | increases oxidation | 1356728 |
| C010262 | norharman | CYP2E1 protein affects the metabolism of [norharman co-treated with aniline] | affects cotreatment|affects metabolic processing | 15279827 |
| C025589 | ochratoxin A | CYP2E1 protein results in increased susceptibility to ochratoxin A | increases response to substance | 11189750 |
| D019787 | Linoleic Acid | Linoleic Acid results in decreased activity of CYP2E1 protein | decreases activity | 16978661 |
| D009828 | Oleanolic Acid | Oleanolic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of and results in increased activity of CYP2E1 protein] | decreases reaction|increases activity|increases expression | 10355542 |
| D009828 | Oleanolic Acid | Oleanolic Acid results in decreased expression of CYP2E1 mRNA | decreases expression | 18706400 |
| D009828 | Oleanolic Acid | Oleanolic Acid results in decreased expression of CYP2E1 mRNA | decreases expression | 18706400 |
| D009853 | Omeprazole | Omeprazole results in increased expression of and results in increased activity of CYP2E1 protein | increases activity|increases expression | 15802389 |
| D009966 | Orphenadrine | Orphenadrine inhibits the reaction [CYP2E1 protein results in decreased ethylation of 7-ethoxy-4-trifluoromethylcoumarin] | decreases ethylation|decreases reaction | 9241656 |
| D009966 | Orphenadrine | Orphenadrine inhibits the reaction [CYP2E1 protein results in increased chemical synthesis of 7-hydroxy-4-trifluoromethylcoumarin] | decreases reaction|increases chemical synthesis | 9241656 |
| D009966 | Orphenadrine | Orphenadrine results in decreased activity of CYP2E1 protein | decreases activity | 9241656 |
| D010126 | Ozone | Ozone results in decreased expression of CYP2E1 mRNA | decreases expression | 12763052 |
| C041786 | palm oil | palm oil results in decreased expression of CYP2E1 mRNA | decreases expression | 18042831 |
| D010269 | Paraquat | [Maneb co-treated with Paraquat] results in increased expression of CYP2E1 mRNA | affects cotreatment|increases expression | 16510128 |
| D010278 | Parathion | CYP2E1 protein affects the metabolism of Parathion | affects metabolic processing | 12669189 |
| C003060 | pentachlorobenzene | CYP2E1 protein results in increased metabolism of pentachlorobenzene | increases metabolic processing | 7747284 |
| C003060 | pentachlorobenzene | CYP2E1 protein results in increased oxidation of pentachlorobenzene | increases oxidation | 7747284 |
| C003060 | pentachlorobenzene | pentachlorobenzene results in increased expression of CYP2E1 protein | increases expression | 10696772 |
| D010416 | Pentachlorophenol | CYP2E1 protein results in increased oxidation of Pentachlorophenol | increases oxidation | 7747284 |
| C023036 | perfluorooctanoic acid | perfluorooctanoic acid results in decreased expression of CYP2E1 mRNA | decreases expression | 17681415 |
| D010615 | Phenacetin | CYP2E1 protein affects the metabolism of Phenacetin | affects metabolic processing | 15879494 |
| C058305 | phenethyl isothiocyanate | phenethyl isothiocyanate inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol] | decreases reaction|increases metabolic processing | 7601153 |
| C058305 | phenethyl isothiocyanate | phenethyl isothiocyanate inhibits the reaction [CYP2E1 protein results in increased metabolism of Carbon Tetrachloride] | decreases reaction|increases metabolic processing | 7601153 |
| C058305 | phenethyl isothiocyanate | phenethyl isothiocyanate inhibits the reaction [[CYP2E1 protein results in increased metabolism of Ethanol] which results in increased chemical synthesis of Acetaldehyde] | decreases reaction|increases chemical synthesis|increases metabolic processing | 7562599 |
| C058305 | phenethyl isothiocyanate | phenethyl isothiocyanate inhibits the reaction [Ethanol results in increased expression of CYP2E1 mRNA] | decreases reaction|increases expression | 7562599 |
| C058305 | phenethyl isothiocyanate | phenethyl isothiocyanate inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein] | decreases reaction|increases expression | 7562599 |
| C058305 | phenethyl isothiocyanate | phenethyl isothiocyanate results in decreased expression of CYP2E1 protein | decreases expression | 7601153 |
| D010634 | Phenobarbital | Choline deficiency promotes the reaction [Phenobarbital results in increased expression of CYP2E1 protein] | increases expression|increases reaction | 18798224 |
| D010634 | Phenobarbital | Phenobarbital results in decreased expression of CYP2E1 mRNA | decreases expression | 15596064 |
| D010634 | Phenobarbital | Phenobarbital results in increased activity of CYP2E1 protein | increases activity | 15490126 |
| D010634 | Phenobarbital | Phenobarbital results in increased expression of CYP2E1 protein | increases expression | 18798224 |
| D019800 | Phenol | CYP2E1 protein results in increased metabolism of Phenol | increases metabolic processing | 11701230 |
| C500434 | phenyl caffeate | phenyl caffeate inhibits the reaction [CYP2E1 protein results in increased hydroxylation of aniline] | decreases reaction|increases hydroxylation | 18436364 |
| D010626 | Phenylethyl Alcohol | CYP2E1 protein results in increased oxidation of Phenylethyl Alcohol | increases oxidation | 7515681 |
| D010672 | Phenytoin | NOC 18 inhibits the reaction [Phenytoin results in increased expression of CYP2E1 mRNA] | decreases reaction|increases expression | 18206661 |
| D010672 | Phenytoin | Phenytoin results in increased expression of CYP2E1 mRNA | increases expression | 18206661 |
| D010672 | Phenytoin | Phenytoin results in increased expression of CYP2E1 protein | increases expression | 18206661 |
| D010936 | Plant Extracts | Plant Extracts results in decreased activity of CYP2E1 protein | decreases activity | 15900287 |
| D010936 | Plant Extracts | Plant Extracts results in increased activity of CYP2E1 protein | increases activity | 15974642 |
| D010936 | Plant Extracts | Plant Extracts results in increased expression of CYP2E1 mRNA | increases expression | 15629189 |
| D010936 | Plant Extracts | Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Diethylnitrosamine] results in increased expression of CYP2E1 protein] | affects cotreatment|decreases reaction|increases expression | 19551842 |
| D010936 | Plant Extracts | Plant Extracts results in decreased expression of CYP2E1 mRNA | decreases expression | 15242186 |
| C025299 | polyphenols | polyphenols results in decreased expression of CYP2E1 mRNA | decreases expression | 19370779 |
| C025299 | polyphenols | polyphenols results in decreased expression of CYP2E1 protein | decreases expression | 19370779 |
| C025299 | polyphenols | polyphenols results in decreased expression of CYP2E1 mRNA | decreases expression | 16293270 |
| D011134 | Polysaccharides | Polysaccharides results in decreased activity of CYP2E1 protein | decreases activity | 17827724 |
| D011335 | Proadifen | Proadifen inhibits the reaction [CYP2E1 protein results in increased metabolism of aniline] | decreases reaction|increases metabolic processing | 8819299 |
| D011335 | Proadifen | Proadifen results in decreased activity of CYP2E1 protein | decreases activity | 15618748 |
| D011374 | Progesterone | Progesterone affects the expression of CYP2E1 mRNA | affects expression | 17251523 |
| D011374 | Progesterone | Progesterone promotes the reaction [Benzene results in decreased activity of CYP2E1 protein] | decreases activity|increases reaction | 18407866 |
| D019840 | 2-Propanol | 2-Propanol binds to and results in increased expression of CYP2E1 protein | affects binding|increases expression | 3337723 |
| D019840 | 2-Propanol | 2-Propanol inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] | decreases reaction|increases reduction | 7710944 |
| D019840 | 2-Propanol | 2-Propanol results in decreased activity of CYP2E1 protein | decreases activity | 7710944 |
| C028255 | propargyl alcohol | CYP2E1 protein results in increased metabolism of propargyl alcohol | increases metabolic processing | 11306107 |
| C045950 | propiconazole | propiconazole results in decreased expression of CYP2E1 protein | decreases expression | 7986207 |
| D011429 | Propolis | Propolis inhibits the reaction [Carbon Tetrachloride results in decreased activity of CYP2E1 protein] | decreases activity|decreases reaction | 17410408 |
| C009091 | protocatechuic acid | [protocatechuic acid co-treated with Methylcholanthrene] results in decreased activity of CYP2E1 protein | affects cotreatment|decreases activity | 15302093 |
| C009091 | protocatechuic acid | protocatechuic acid results in decreased activity of CYP2E1 protein | decreases activity | 15302093 |
| C033607 | puerarin | puerarin inhibits the reaction [CYP2E1 protein results in increased hydroxylation of aniline] | decreases reaction|increases hydroxylation | 18038910 |
| C033607 | puerarin | puerarin results in increased expression of CYP2E1 protein | increases expression | 18038910 |
| C026133 | purpurogallin | purpurogallin inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] | decreases reaction|increases reduction | 7710944 |
| D011719 | Pyrazines | allyl sulfide inhibits the reaction [Pyrazines results in increased activity of CYP2E1 protein] | decreases reaction|increases activity | 8117321 |
| D011719 | Pyrazines | allyl sulfide inhibits the reaction [Pyrazines results in increased expression of CYP2E1 protein] | decreases reaction|increases expression | 8117321 |
| D011719 | Pyrazines | Pyrazines results in increased activity of CYP2E1 protein | increases activity | 8117321 |
| D011719 | Pyrazines | Pyrazines results in increased expression of CYP2E1 protein | increases expression | 8117321 |
| C031280 | pyrazole | pyrazole results in increased expression of CYP2E1 protein | increases expression | 8074729 |
| C031280 | pyrazole | pyrazole results in increased expression of CYP2E1 protein | increases expression | 9698299 |
| C031280 | pyrazole | pyrazole results in increased activity of CYP2E1 protein | increases activity | 3782137 8734847 |
| C031280 | pyrazole | pyrazole results in increased expression of CYP2E1 protein | increases expression | 3782137 3113478 8734847 |
| C023666 | pyridine | CYP2E1 protein promotes the reaction [pyridine results in increased expression of CYP1A1 mRNA] | increases expression|increases reaction | 12147272 |
| C023666 | pyridine | Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein promotes the reaction [pyridine results in increased expression of CYP1A1 mRNA]] | decreases reaction|increases expression|increases reaction | 12147272 |
| C023666 | pyridine | pyridine results in decreased activity of CYP2E1 protein | decreases activity | 12464242 |
| C023666 | pyridine | pyridine results in increased expression of CYP2E1 protein | increases expression | 8074729 |
| C023666 | pyridine | pyridine results in increased expression of CYP2E1 protein | increases expression | 8246169 |
| C023666 | pyridine | Cycloheximide inhibits the reaction [pyridine results in increased activity of CYP2E1 protein] | decreases reaction|increases activity | 1968335 |
| C023666 | pyridine | Cycloheximide inhibits the reaction [pyridine results in increased expression of CYP2E1 protein] | decreases reaction|increases expression | 1968335 |
| C023666 | pyridine | Ditiocarb inhibits the reaction [pyridine results in increased activity of CYP2E1 protein] | decreases reaction|increases activity | 9618253 |
| C023666 | pyridine | INS protein affects the reaction [pyridine results in increased expression of CYP2E1 protein] | affects reaction|increases expression | 10215695 |
| C023666 | pyridine | [pyridine co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 mRNA | affects cotreatment|decreases expression | 8734847 |
| C023666 | pyridine | [pyridine co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 protein | affects cotreatment|decreases expression | 8734847 |
| C023666 | pyridine | [pyridine co-treated with Methylcholanthrene] results in increased activity of CYP2E1 protein | affects cotreatment|increases activity | 8734847 |
| C023666 | pyridine | [pyridine co-treated with Methylcholanthrene] results in increased expression of CYP2E1 protein | affects cotreatment|increases expression | 8734847 |
| C023666 | pyridine | pyridine promotes the reaction [ciprofibrate results in increased expression of CYP2E1 protein] | increases expression|increases reaction | 7587954 |
| C023666 | pyridine | pyridine promotes the reaction [CYP2E1 protein results in increased hydroxylation of 4-nitrophenol] | increases hydroxylation|increases reaction | 9618253 |
| C023666 | pyridine | pyridine results in increased activity of CYP2E1 protein | increases activity | 8734847 1968335 9618253 11181506 1610360 12919724 8246169 |
| C023666 | pyridine | pyridine results in increased expression of CYP2E1 mRNA | increases expression | 1379807 2241968 |
| C023666 | pyridine | pyridine results in increased expression of CYP2E1 protein | increases expression | 1379807 8246169 7587954 2241968 8734847 9618253 1968335 12919724 11181506 10215695 1610360 |
| C013229 | pyridine N-oxide | pyridine N-oxide results in increased expression of CYP2E1 protein | increases expression | 1379807 |
| D011794 | Quercetin | Quercetin inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] | decreases reaction|increases reduction | 7710944 |
| D011794 | Quercetin | Quercetin inhibits the reaction [INS1 protein results in decreased expression of CYP2E1 mRNA] | decreases expression|decreases reaction | 11306697 |
| D011796 | Quinacrine | Quinacrine binds to and results in decreased activity of CYP2E1 protein | affects binding|decreases activity | 18754103 |
| D011796 | Quinacrine | Quinacrine results in decreased expression of CYP2E1 protein | decreases expression | 18754103 |
| C037219 | quinoline | CYP2E1 protein results in increased hydroxylation of quinoline | increases hydroxylation | 8824525 |
| C037219 | quinoline | CYP2E1 protein results in increased hydroxylation of quinoline | increases hydroxylation | 8824525 |
| D017382 | Reactive Oxygen Species | [CYP2E1 protein results in increased metabolism of Ethanol] which results in increased abundance of Reactive Oxygen Species | increases abundance|increases metabolic processing | 18845238 |
| D017382 | Reactive Oxygen Species | fomepizole inhibits the reaction [[CYP2E1 protein results in increased metabolism of Ethanol] which results in increased abundance of Reactive Oxygen Species] | decreases reaction|increases abundance|increases metabolic processing | 18845238 |
| D017382 | Reactive Oxygen Species | CYP2E1 protein affects the chemical synthesis of Reactive Oxygen Species | affects chemical synthesis | 14693714 |
| D017382 | Reactive Oxygen Species | CYP2E1 protein results in decreased susceptibility to Reactive Oxygen Species | decreases response to substance | 12470497 |
| C059514 | resveratrol | resveratrol analog results in decreased activity of CYP2E1 protein | decreases activity | 16684708 |
| C059514 | resveratrol | resveratrol affects the expression of CYP2E1 mRNA | affects expression | 15748624 |
| D012293 | Rifampin | Rifampin results in increased activity of CYP2E1 protein | increases activity | 18071298 |
| D012293 | Rifampin | Rifampin results in increased expression of CYP2E1 mRNA | increases expression | 18071298 |
| D012293 | Rifampin | Rifampin inhibits the reaction [Isoniazid results in increased expression of CYP2E1 protein] | decreases reaction|increases expression | 15132840 |
| D012451 | Safrole | Safrole results in decreased activity of CYP2E1 protein | decreases activity | 15778010 |
| C018142 | saiko-keishi-to | saiko-keishi-to results in increased expression of CYP2E1 mRNA | increases expression | 14607025 |
| C042431 | S-ethyl glutathione | S-ethyl glutathione inhibits the reaction [CYP2E1 protein results in increased susceptibility to Styrene] | decreases reaction|increases response to substance | 16872732 |
| C461320 | shosaiko-to | shosaiko-to results in increased expression of CYP2E1 mRNA | increases expression | 14607025 |
| D012838 | Silymarin | Silymarin inhibits the reaction [Carbon Tetrachloride results in decreased activity of CYP2E1 protein] | decreases activity|decreases reaction | 17410408 |
| D012906 | Smoke | Smoke inhibits the reaction [CYP2E1 protein affects the metabolism of Styrene] | affects metabolic processing|decreases reaction | 16125881 |
| C017947 | sodium arsenite | CYP2E1 protein results in decreased susceptibility to sodium arsenite | decreases response to substance | 19154403 |
| C017947 | sodium arsenite | sodium arsenite results in decreased expression of CYP2E1 mRNA | decreases expression | 17350061 17451858 |
| D012982 | Sodium, Dietary | CYP2E1 gene polymorphism affects the susceptibility to Sodium, Dietary | affects response to substance | 14696128 |
| D019311 | Staurosporine | Staurosporine inhibits the reaction [INS1 protein results in decreased expression of CYP2E1 mRNA] | decreases expression|decreases reaction | 11306697 |
| D019311 | Staurosporine | Staurosporine results in increased expression of CYP2E1 mRNA | increases expression | 11306697 |
| D013311 | Streptozocin | Streptozocin results in decreased expression of CYP2E1 protein | decreases expression | 12700423 |
| D013311 | Streptozocin | Streptozocin results in increased expression of CYP2E1 mRNA | increases expression | 11752103 |
| D013311 | Streptozocin | Streptozocin results in increased expression of CYP2E1 protein | increases expression | 14693714 |
| D020058 | Styrene | CYP2E1 gene polymorphism affects the metabolism of Styrene | affects metabolic processing | 12893075 |
| D020058 | Styrene | CYP2E1 gene polymorphism affects the susceptibility to Styrene | affects response to substance | 14751678 12604177 |
| D020058 | Styrene | CYP2E1 gene polymorphism results in decreased metabolism of Styrene | decreases metabolic processing | 16125881 |
| D020058 | Styrene | CYP2E1 gene polymorphism results in increased susceptibility to Styrene | increases response to substance | 11535253 |
| D020058 | Styrene | CYP2E1 protein affects the metabolism of Styrene | affects metabolic processing | 12464798 |
| D020058 | Styrene | CYP2E1 protein affects the oxidation of Styrene | affects oxidation | 16872732 |
| D020058 | Styrene | CYP2E1 protein results in increased susceptibility to Styrene | increases response to substance | 16872732 |
| D020058 | Styrene | Glutathione inhibits the reaction [CYP2E1 protein results in increased susceptibility to Styrene] | decreases reaction|increases response to substance | 16872732 |
| D020058 | Styrene | GSTM1 protein affects the reaction [CYP2E1 protein affects the metabolism of Styrene] | affects metabolic processing|affects reaction | 12464798 |
| D020058 | Styrene | S-ethyl glutathione inhibits the reaction [CYP2E1 protein results in increased susceptibility to Styrene] | decreases reaction|increases response to substance | 16872732 |
| D020058 | Styrene | Smoke inhibits the reaction [CYP2E1 protein affects the metabolism of Styrene] | affects metabolic processing|decreases reaction | 16125881 |
| D020058 | Styrene | CYP2E1 protein affects the metabolism of Styrene | affects metabolic processing | 12746132 |
| D020058 | Styrene | CYP2E1 protein results in increased susceptibility to Styrene | increases response to substance | 15110085 |
| D020058 | Styrene | [Ditiocarb co-treated with CYP2E1 gene mutant form] results in decreased metabolism of Styrene | affects cotreatment|decreases metabolic processing | 12746132 |
| D020058 | Styrene | gadolinium chloride inhibits the reaction [Styrene results in increased expression of CYP2E1 mRNA] | decreases reaction|increases expression | 18202523 |
| D020058 | Styrene | gadolinium chloride inhibits the reaction [Styrene results in increased expression of CYP2E1 protein] | decreases reaction|increases expression | 18202523 |
| D020058 | Styrene | Styrene results in increased expression of CYP2E1 mRNA | increases expression | 18202523 16418063 |
| D020058 | Styrene | Styrene results in increased expression of CYP2E1 protein | increases expression | 16418063 18202523 |
| D013438 | Sulfhydryl Compounds | Sulfhydryl Compounds results in decreased expression of CYP2E1 protein | decreases expression | 8117321 |
| D014284 | Triiodothyronine | Triiodothyronine results in increased activity of CYP2E1 protein | increases activity | 14631868 |
| D014284 | Triiodothyronine | Triiodothyronine results in increased expression of CYP2E1 protein | increases expression | 14631868 |
| C003377 | taxifolin | taxifolin results in decreased expression of CYP2E1 mRNA | decreases expression | 17541156 |
| C489139 | t-butyl acetylene | cumene hydroperoxide inhibits the reaction [t-butyl acetylene results in decreased activity of CYP2E1 protein mutant form] | decreases activity|decreases reaction | 15379534 |
| C489139 | t-butyl acetylene | cumene hydroperoxide promotes the reaction [t-butyl acetylene results in decreased activity of CYP2E1 protein] | decreases activity|increases reaction | 15379534 |
| C489139 | t-butyl acetylene | t-butyl acetylene results in decreased activity of CYP2E1 protein | decreases activity | 15379534 |
| C489139 | t-butyl acetylene | t-butyl acetylene results in decreased activity of CYP2E1 protein mutant form | decreases activity | 15379534 |
| C489139 | t-butyl acetylene | tert-Butylhydroperoxide promotes the reaction [t-butyl acetylene results in decreased activity of CYP2E1 protein] | decreases activity|increases reaction | 15379534 |
| C489139 | t-butyl acetylene | tert-Butylhydroperoxide promotes the reaction [t-butyl acetylene results in decreased activity of CYP2E1 protein mutant form] | decreases activity|increases reaction | 15379534 |
| D013662 | Tea | Tea results in decreased expression of CYP2E1 mRNA | decreases expression | 19370779 |
| D013662 | Tea | Tea results in decreased expression of CYP2E1 protein | decreases expression | 19370779 |
| C001803 | tempol | tempol inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] | decreases reaction|increases reduction | 7710944 |
| D013739 | Testosterone | Testosterone results in increased expression of CYP2E1 protein | increases expression | 7839370 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in decreased expression of CYP2E1 mRNA | decreases expression | 20106945 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin affects the expression of CYP2E1 mRNA | affects expression | 17949056 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of CYP2E1 mRNA | increases expression | 16120747 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in decreased expression of CYP2E1 mRNA | decreases expression | 18796159 16054898 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of CYP2E1 mRNA | increases expression | 19969063 |
| D013750 | Tetrachloroethylene | CYP2E1 protein results in increased susceptibility to Tetrachloroethylene | increases response to substance | 17433522 |
| C009408 | tetrachlorophenol | CYP2E1 protein results in increased oxidation of tetrachlorophenol | increases oxidation | 7747284 |
| D013755 | Tetradecanoylphorbol Acetate | Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]] | decreases reaction|increases oxidation|increases reaction | 9143349 |
| D013755 | Tetradecanoylphorbol Acetate | Tetradecanoylphorbol Acetate inhibits the reaction [Cycloheximide inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]] | decreases reaction|increases oxidation | 8531136 |
| D013755 | Tetradecanoylphorbol Acetate | Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol] | increases oxidation|increases reaction | 9143349 8531136 |
| D013755 | Tetradecanoylphorbol Acetate | Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased susceptibility to Ethanol] | increases reaction|increases response to substance | 8798623 |
| D013755 | Tetradecanoylphorbol Acetate | Tetradecanoylphorbol Acetate results in increased expression of CYP2E1 protein | increases expression | 8798623 |
| D013805 | Theobromine | 4-nitrophenol inhibits the reaction [CYP2E1 protein results in increased metabolism of Theobromine] | decreases reaction|increases metabolic processing | 10215755 |
| D013805 | Theobromine | CYP2E1 protein results in increased metabolism of Theobromine | increases metabolic processing | 10215755 |
| D013805 | Theobromine | Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of Theobromine] | decreases reaction|increases metabolic processing | 10215755 |
| D013806 | Theophylline | CYP2E1 protein affects the metabolism of Theophylline | affects metabolic processing | 15948934 |
| D013806 | Theophylline | CYP2E1 protein affects the metabolism of Theophylline | affects metabolic processing | 15985363 |
| D013830 | Thiadiazoles | Thiadiazoles analog results in decreased activity of CYP2E1 protein | decreases activity | 9188722 |
| D013844 | Thiazoles | [Thiazoles co-treated with ciprofibrate] results in increased expression of CYP2E1 protein | affects cotreatment|increases expression | 7587954 |
| D013853 | Thioacetamide | CYP2E1 protein affects the reaction [Thioacetamide results in decreased expression of GPX1 mRNA] | affects reaction|decreases expression | 18374380 |
| D013853 | Thioacetamide | CYP2E1 protein affects the reaction [Thioacetamide results in increased expression of IL6 mRNA] | affects reaction|increases expression | 18374380 |
| D013853 | Thioacetamide | CYP2E1 protein affects the reaction [Thioacetamide results in increased expression of NOS2 protein] | affects reaction|increases expression | 18374380 |
| D013853 | Thioacetamide | CYP2E1 protein affects the reaction [Thioacetamide results in increased expression of TNF mRNA] | affects reaction|increases expression | 18374380 |
| D013853 | Thioacetamide | CYP2E1 protein results in increased susceptibility to Thioacetamide | increases response to substance | 18374380 |
| D013853 | Thioacetamide | Thioacetamide results in decreased expression of CYP2E1 mRNA | decreases expression | 16297948 |
| D013875 | Thiophanate | Thiophanate results in increased expression of CYP2E1 protein | increases expression | 10096430 |
| D013881 | Thioridazine | Thioridazine results in decreased activity of CYP2E1 protein | decreases activity | 15135088 |
| D013893 | Thiram | CYP2E1 protein results in increased metabolism of Thiram | increases metabolic processing | 12458634 |
| D013893 | Thiram | Thiram inhibits the reaction [Isoniazid results in increased activity of CYP2E1 protein] | decreases reaction|increases activity | 12458634 |
| C049947 | tirapazamine | 1-phenylimidazole inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] | decreases reaction|increases reduction | 7710944 |
| C049947 | tirapazamine | 2-Propanol inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] | decreases reaction|increases reduction | 7710944 |
| C049947 | tirapazamine | caffeic acid inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] | decreases reaction|increases reduction | 7710944 |
| C049947 | tirapazamine | CAT protein inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] | decreases reaction|increases reduction | 7710944 |
| C049947 | tirapazamine | CYP2E1 protein results in increased reduction of and results in increased activity of and results in increased susceptibility to tirapazamine | increases activity|increases reduction|increases response to substance | 7710944 |
| C049947 | tirapazamine | Deferoxamine inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] | decreases reaction|increases reduction | 7710944 |
| C049947 | tirapazamine | Dicumarol promotes the reaction [CYP2E1 protein results in increased reduction of tirapazamine] | increases reaction|increases reduction | 7710944 |
| C049947 | tirapazamine | Ethanol inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] | decreases reaction|increases reduction | 7710944 |
| C049947 | tirapazamine | Isoniazid inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] | decreases reaction|increases reduction | 7710944 |
| C049947 | tirapazamine | purpurogallin inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] | decreases reaction|increases reduction | 7710944 |
| C049947 | tirapazamine | Quercetin inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] | decreases reaction|increases reduction | 7710944 |
| C049947 | tirapazamine | tempol inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] | decreases reaction|increases reduction | 7710944 |
| D014050 | Toluene | CYP2E1 protein affects the metabolism of Toluene | affects metabolic processing | 8592870 |
| D014050 | Toluene | Ditiocarb inhibits the reaction [CYP2E1 protein affects the metabolism of Toluene] | affects metabolic processing|decreases reaction | 8592870 |
| D014050 | Toluene | fomepizole inhibits the reaction [CYP2E1 protein affects the metabolism of Toluene] | affects metabolic processing|decreases reaction | 8592870 |
| D014050 | Toluene | CYP2E1 gene polymorphism affects the susceptibility to Toluene | affects response to substance | 17292523 |
| D014050 | Toluene | CYP2E1 protein results in increased metabolism of Toluene | increases metabolic processing | 18350910 12464242 8558417 |
| D014050 | Toluene | Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of Toluene] | decreases reaction|increases metabolic processing | 8558417 |
| D014050 | Toluene | Toluene results in increased expression of CYP2E1 mRNA | increases expression | 16581535 |
| D014050 | Toluene | Acetone promotes the reaction [Toluene results in increased expression of CYP2E1 protein] | increases expression|increases reaction | 8996725 |
| D014050 | Toluene | Toluene promotes the reaction [CYP2E1 protein results in increased metabolism of Methylene Chloride] | increases metabolic processing|increases reaction | 8889796 |
| D014050 | Toluene | Toluene results in increased activity of CYP2E1 protein | increases activity | 8889796 12919724 |
| D014050 | Toluene | Toluene results in increased expression of CYP2E1 mRNA | increases expression | 12919724 |
| D014050 | Toluene | Toluene results in increased expression of CYP2E1 protein | increases expression | 8996725 12919724 |
| D014050 | Toluene | Disulfiram inhibits the reaction [Toluene results in increased activity of CYP2E1 protein] | decreases reaction|increases activity | 12781212 |
| D014050 | Toluene | Toluene results in increased activity of CYP2E1 protein | increases activity | 12781212 |
| D014107 | Tosyllysine Chloromethyl Ketone | Tosyllysine Chloromethyl Ketone inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] | decreases reaction|increases degradation | 9143349 |
| C507866 | trans-1,2-dihydro-1,2-naphthalenediol | CYP2E1 protein results in increased abundance of trans-1,2-dihydro-1,2-naphthalenediol | increases abundance | 16243959 |
| D014191 | Tranylcypromine | Tranylcypromine results in decreased activity of CYP2E1 protein | decreases activity | 15155557 |
| D014212 | Tretinoin | Tretinoin promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol] | increases oxidation|increases reaction | 8531136 |
| D014212 | Tretinoin | CYP2E1 protein results in increased metabolism of Tretinoin | increases metabolic processing | 16054987 |
| D014212 | Tretinoin | Ethanol promotes the reaction [CYP2E1 protein results in increased metabolism of Tretinoin] | increases metabolic processing|increases reaction | 16054987 |
| C032910 | triadimefon | triadimefon results in decreased expression of CYP2E1 mRNA | decreases expression | 16730040 |
| D014241 | Trichloroethylene | CYP2E1 protein affects the metabolism of Trichloroethylene | affects metabolic processing | 17710613 |
| D014241 | Trichloroethylene | CYP2E1 protein results in increased metabolism of Trichloroethylene | increases metabolic processing | 18350910 10841534 |
| D014241 | Trichloroethylene | Trichloroethylene results in increased activity of CYP2E1 protein | increases activity | 17710613 |
| D014241 | Trichloroethylene | 1,2-dichloroethylene inhibits the reaction [CYP2E1 protein affects the metabolism of Trichloroethylene] | affects metabolic processing|decreases reaction | 7871537 |
| D014241 | Trichloroethylene | CYP2E1 protein affects the metabolism of Trichloroethylene | affects metabolic processing | 7871537 17710613 |
| D014241 | Trichloroethylene | CYP2E1 protein results in increased susceptibility to Trichloroethylene | increases response to substance | 17433522 |
| D014241 | Trichloroethylene | Trichloroethylene inhibits the reaction [Acetone results in increased activity of CYP2E1 protein] | decreases reaction|increases activity | 9851676 |
| D014241 | Trichloroethylene | Trichloroethylene results in increased activity of CYP2E1 protein | increases activity | 17710613 |
| C025280 | trichloromethyl free radical | [CYP2E1 protein results in increased metabolism of Carbon Tetrachloride] which results in increased abundance of trichloromethyl free radical | increases abundance|increases metabolic processing | 19336974 |
| D014501 | Uranium | [Acetaminophen co-treated with Uranium analog] results in decreased expression of CYP2E1 mRNA | affects cotreatment|decreases expression | 17126469 |
| D014501 | Uranium | Uranium analog promotes the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA] | increases expression|increases reaction | 17126469 |
| D014520 | Urethane | 1-aminobenzotriazole inhibits the reaction [CYP2E1 protein affects the metabolism of Urethane] | affects metabolic processing|decreases reaction | 12704224 |
| D014520 | Urethane | CYP2E1 gene mutant form inhibits the reaction [Urethane affects the expression of MKI67 protein] | affects expression|decreases reaction | 15790490 |
| D014520 | Urethane | CYP2E1 gene mutant form results in decreased metabolism of Urethane | decreases metabolic processing | 12704224 |
| D014520 | Urethane | CYP2E1 gene mutant form results in decreased susceptibility to Urethane | decreases response to substance | 17093202 |
| D014520 | Urethane | CYP2E1 protein affects the hydroxylation of Urethane | affects hydroxylation | 15879495 |
| D014520 | Urethane | CYP2E1 protein affects the metabolism of Urethane | affects metabolic processing | 12704224 15879495 17979661 |
| D014520 | Urethane | CYP2E1 protein results in increased susceptibility to Urethane | increases response to substance | 15790490 |
| D014520 | Urethane | [Urethane co-treated with Ethanol] results in increased activity of CYP2E1 protein | affects cotreatment|increases activity | 15582191 |
| D014520 | Urethane | CYP2E1 affects the oxidation of Urethane | affects oxidation | 17341656 |
| D014520 | Urethane | CYP2E1 protein affects the oxidation of Urethane | affects oxidation | 17093202 |
| C043425 | vanoxerine | [Chlorzoxazone results in decreased activity of CYP2E1 protein] which results in decreased degradation of vanoxerine | decreases activity|decreases degradation | 11502731 |
| C043425 | vanoxerine | CYP2E1 protein results in decreased degradation of vanoxerine | decreases degradation | 11502731 |
| C025643 | vinclozolin | [acephate co-treated with vinclozolin] affects the expression of CYP2E1 protein | affects cotreatment|affects expression | 17686559 |
| C025643 | vinclozolin | [fenarimol co-treated with vinclozolin] affects the expression of CYP2E1 protein | affects cotreatment|affects expression | 17686559 |
| C025643 | vinclozolin | [fenarimol co-treated with vinclozolin co-treated with acephate] affects the expression of CYP2E1 protein | affects cotreatment|affects expression | 17686559 |
| C025643 | vinclozolin | vinclozolin affects the expression of CYP2E1 mRNA | affects expression | 8921505 |
| C025643 | vinclozolin | vinclozolin affects the expression of CYP2E1 protein | affects expression | 8921505 |
| C017963 | vinyl carbamate | CYP2E1 protein affects the metabolism of vinyl carbamate | affects metabolic processing | 11181492 |
| C017963 | vinyl carbamate | [vinyl carbamate co-treated with NADP] inhibits the reaction [CYP2E1 protein results in decreased methylation of Dimethylnitrosamine] | affects cotreatment|decreases methylation|decreases reaction | 11181492 |
| C017963 | vinyl carbamate | CYP2E1 protein affects the metabolism of vinyl carbamate | affects metabolic processing | 11181492 |
| C017963 | vinyl carbamate | diallyl sulfone inhibits the reaction [CYP2E1 protein affects the oxidation of vinyl carbamate] | affects oxidation|decreases reaction | 17341656 |
| C017963 | vinyl carbamate | vinyl carbamate results in decreased activity of CYP2E1 protein | decreases activity | 11134547 |
| C017963 | vinyl carbamate | vinyl carbamate results in decreased expression of CYP2E1 protein | decreases expression | 11134547 |
| C017963 | vinyl carbamate | CYP2E1 protein affects the oxidation of vinyl carbamate | affects oxidation | 17296623 |
| C017963 | vinyl carbamate | diallyl sulfone inhibits the reaction [CYP2E1 protein affects the oxidation of vinyl carbamate] | affects oxidation|decreases reaction | 17296623 |
| D014752 | Vinyl Chloride | CYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride affects the mutagenesis of KRAS gene] | affects mutagenesis|increases reaction | 12705718 |
| D014752 | Vinyl Chloride | CYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene] | affects mutagenesis|increases reaction | 12705718 |
| D014752 | Vinyl Chloride | CYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride results in increased mutagenesis of KRAS gene] | increases mutagenesis|increases reaction | 17384900 |
| D014752 | Vinyl Chloride | CYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride results in increased mutagenesis of TP53 gene] | increases mutagenesis|increases reaction | 17384900 12010862 |
| D014752 | Vinyl Chloride | CYP2E1 gene polymorphism results in increased susceptibility to Vinyl Chloride | increases response to substance | 16270392 |
| D014752 | Vinyl Chloride | CYP2E1 gene SNP results in increased susceptibility to Vinyl Chloride | increases response to substance | 18420361 20100738 |
| D014752 | Vinyl Chloride | CYP2E1 protein affects the metabolism of Vinyl Chloride | affects metabolic processing | 17710613 |
| D014752 | Vinyl Chloride | CYP2E1 protein results in increased metabolism of Vinyl Chloride | increases metabolic processing | 18350910 |
| D014752 | Vinyl Chloride | Vinyl Chloride results in increased activity of CYP2E1 protein | increases activity | 17710613 |
| D014752 | Vinyl Chloride | 1,2-dichloroethylene inhibits the reaction [CYP2E1 protein affects the metabolism of Vinyl Chloride] | affects metabolic processing|decreases reaction | 7871537 |
| D014752 | Vinyl Chloride | CYP2E1 protein affects the metabolism of Vinyl Chloride | affects metabolic processing | 17710613 7871537 |
| D014752 | Vinyl Chloride | Vinyl Chloride results in increased activity of CYP2E1 protein | increases activity | 17710613 15211785 |
| D014752 | Vinyl Chloride | CYP2E1 protein affects the metabolism of Vinyl Chloride | affects metabolic processing | 18420361 |
| C029297 | vinylidene chloride | CYP2E1 protein results in increased metabolism of vinylidene chloride | increases metabolic processing | 10215634 15319346 |
| C029297 | vinylidene chloride | diallyl sulfone inhibits the reaction [CYP2E1 protein results in increased metabolism of vinylidene chloride] | decreases reaction|increases metabolic processing | 10215634 |
| C029297 | vinylidene chloride | CYP2E1 protein results in increased metabolism of vinylidene chloride | increases metabolic processing | 15319346 11356946 |
| C029297 | vinylidene chloride | CYP2E1 protein results in increased metabolism of vinylidene chloride | increases metabolic processing | 15319346 |
| D014801 | Vitamin A | CYP2E1 protein results in increased metabolism of Vitamin A | increases metabolic processing | 16054987 |
| D014801 | Vitamin A | Ethanol promotes the reaction [CYP2E1 protein results in increased metabolism of Vitamin A] | increases metabolic processing|increases reaction | 16054987 |
| C009687 | wortmannin | wortmannin inhibits the reaction [INS1 protein results in decreased expression of CYP2E1 mRNA] | decreases expression|decreases reaction | 11306697 |
| C098009 | YH 439 | YH 439 inhibits the reaction [Acetaminophen results in increased phosphorylation of and results in increased activity of CYP2E1 protein] | decreases reaction|increases activity|increases phosphorylation | 11562448 |
| C098009 | YH 439 | YH 439 results in decreased expression of and results in decreased activity of CYP2E1 protein | decreases activity|decreases expression | 11562448 |
| C098009 | YH 439 | YH 439 results in decreased expression of CYP2E1 mRNA | decreases expression | 11562448 |
| D019287 | Zinc Sulfate | Zinc Sulfate inhibits the reaction [Ethanol results in increased activity of CYP2E1 protein] | decreases reaction|increases activity | 15920153 |
| D019287 | Zinc Sulfate | Zinc Sulfate inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein] | decreases reaction|increases expression | 15920153 |
| D015049 | Zoxazolamine | CYP2E1 protein results in increased metabolism of and results in decreased activity of Zoxazolamine | decreases activity|increases metabolic processing | 16109766 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000014 | Abnormalities, Drug-Induced | 1,2-dichloroethylene | 18.87 | 8449394 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Disulfiram | 18.87 | 17676605 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Ethanol | 18.87 | 18926900 17676605 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Maneb | 18.87 | 982313 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Phenobarbital | 18.87 | 6195326 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Phenytoin | 18.87 | 6195326 9118846 9677735 8986270 3425630 10563481 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Tetrachlorodibenzodioxin | 18.87 | 11752688 14514962 15322242 | |
| MESH:D000015 | Abnormalities, Multiple | Vitamin A | 3.54 | 10992263 | |
| MESH:D000022 | Abortion, Spontaneous | bromodichloromethane | 5.43 | 14691210 12970577 | |
| MESH:D000038 | Abscess | Drugs, Chinese Herbal | 4.85 | 15043669 | |
| MESH:D000138 | Acidosis | Ammonium Chloride | 9.69 | 18287403 | |
| MESH:D000138 | Acidosis | Ethanol | 9.69 | 11192467 | |
| MESH:D000138 | Acidosis | Zinc Sulfate | 9.69 | 7265320 | |
| MESH:D000163 | Acquired Immunodeficiency Syndrome | Disulfiram | 4.15 | 9207937 | |
| MESH:D058186 | Acute Kidney Injury | resveratrol | 2.59 | 16538975 | |
| MESH:D055371 | Acute Lung Injury | 3-xylene | 5.42 | 15204773 | |
| MESH:D055371 | Acute Lung Injury | Lipopolysaccharides | 5.42 | 11850527 18653653 | |
| MESH:D000230 | Adenocarcinoma | marker/mechanism | 16142352 | ||
| MESH:D000230 | Adenocarcinoma | arsenic trioxide | 10.21 | 11798837 19825857 | |
| MESH:D000230 | Adenocarcinoma | Benzo(a)pyrene | 10.21 | 20127859 20464547 | |
| MESH:D000230 | Adenocarcinoma | Dimethylnitrosamine | 10.21 | 16033868 | |
| MESH:D000230 | Adenocarcinoma | Estradiol | 10.21 | 11473722 | |
| MESH:D000230 | Adenocarcinoma | Indomethacin | 10.21 | 16537180 | |
| MESH:D000230 | Adenocarcinoma | Urethane | 10.21 | 18316556 | |
| MESH:D000230 | Adenocarcinoma | vinyl carbamate | 10.21 | 17363558 16247444 | |
| MESH:D002282 | Adenocarcinoma, Bronchiolo-Alveolar | Urethane | 4.26 | 15814487 | |
| MESH:D000236 | Adenoma | 2,6-xylidine | 32.77 | 10945294 | |
| MESH:D000236 | Adenoma | 2-Acetylaminofluorene | 32.77 | 10737359 | |
| MESH:D000236 | Adenoma | 4-dichlorobenzene | 32.77 | 12748734 | |
| MESH:D000236 | Adenoma | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 32.77 | 16176798 | |
| MESH:D000236 | Adenoma | Benzo(a)pyrene | 32.77 | 6695378 | |
| MESH:D000236 | Adenoma | beta-Naphthoflavone | 32.77 | 19389873 | |
| MESH:D000236 | Adenoma | Diethylnitrosamine | 32.77 | 6695378 10737359 | |
| MESH:D000236 | Adenoma | Dimethylnitrosamine | 32.77 | 19555203 | |
| MESH:D000236 | Adenoma | Indomethacin | 32.77 | 11497255 | |
| MESH:D000236 | Adenoma | Methylcholanthrene | 32.77 | 10545420 6695378 | |
| MESH:D000236 | Adenoma | resveratrol | 32.77 | 15688382 | |
| MESH:D000236 | Adenoma | Urethane | 32.77 | 10822126 11497255 6695378 10530776 16926031 17093202 17195641 | |
| MESH:D002759 | Adenoma, Bile Duct | 2-Acetylaminofluorene | 4.55 | 6705139 | |
| MESH:D018248 | Adenoma, Liver Cell | Diethylnitrosamine | 13.46 | 19061943 19052882 16434500 17620307 18056438 17162532 | |
| MESH:D018248 | Adenoma, Liver Cell | Phenobarbital | 13.46 | 17620307 | |
| MESH:D018248 | Adenoma, Liver Cell | Tetrachlorodibenzodioxin | 13.46 | 16835633 | |
| MESH:D018248 | Adenoma, Liver Cell | vinyl carbamate | 13.46 | 12371669 | |
| MESH:D000310 | Adrenal Gland Neoplasms | Pentachlorophenol | 8.49 | 10696769 | |
| MESH:D000310 | Adrenal Gland Neoplasms | sodium arsenite | 8.49 | 15276417 | |
| MESH:D018246 | Adrenocortical Adenoma | Arsenic | 8.98 | 17306315 | |
| MESH:D018246 | Adrenocortical Adenoma | sodium arsenite | 8.98 | 16712894 17306315 | |
| MESH:D000382 | Agricultural Workers' Diseases | Atrazine | 12.16 | 11874814 | |
| MESH:D000382 | Agricultural Workers' Diseases | Lindane | 12.16 | 12661182 | |
| MESH:D000382 | Agricultural Workers' Diseases | Maneb | 12.16 | 8807224 | |
| MESH:D000382 | Agricultural Workers' Diseases | Paraquat | 12.16 | 11874814 | |
| MESH:D000382 | Agricultural Workers' Diseases | Parathion | 12.16 | 11874814 17119214 | |
| MESH:D020268 | Alcohol-Induced Disorders, Nervous System | Ethanol | 3.86 | 15451039 15451040 | |
| MESH:D000437 | Alcoholism | Disulfiram | 3.77 | 10841824 18968458 17079463 | |
| MESH:D019973 | Alcohol-Related Disorders | Curcumin | 8.81 | 17887948 | |
| MESH:D019973 | Alcohol-Related Disorders | puerarin | 8.81 | 17887948 | |
| MESH:D000505 | Alopecia | Tretinoin | 2.39 | 15955085 | |
| MESH:D016301 | Alveolar Bone Loss | Indomethacin | 3.91 | 17225004 | |
| MESH:D000544 | Alzheimer Disease | Androgens | 11.35 | 17917157 17182789 | |
| MESH:D000544 | Alzheimer Disease | Curcumin | 11.35 | 15590663 | |
| MESH:D000544 | Alzheimer Disease | Indomethacin | 11.35 | 17627676 15579461 | |
| MESH:D000544 | Alzheimer Disease | Nicotine | 11.35 | 16627626 | |
| MESH:D000544 | Alzheimer Disease | Nitric Oxide | 11.35 | 17556102 | |
| MESH:D000544 | Alzheimer Disease | Ozone | 11.35 | 15513908 | |
| MESH:D000544 | Alzheimer Disease | Plant Extracts | 11.35 | 16962711 | |
| MESH:D000544 | Alzheimer Disease | resveratrol | 11.35 | 16183991 16162502 | |
| MESH:D000707 | Anaphylaxis | mangiferin | 4.07 | 16536907 14669257 | |
| MESH:D000740 | Anemia | Drugs, Chinese Herbal | 10.75 | 17963324 15504547 | |
| MESH:D000740 | Anemia | Phenacetin | 10.75 | 2444515 | |
| MESH:D000740 | Anemia | Tetrachlorodibenzodioxin | 10.75 | 11748828 | |
| MESH:D000740 | Anemia | Vitamin A | 10.75 | 16960172 | |
| MESH:D000741 | Anemia, Aplastic | Benzene | 3.15 | 17661222 11369114 14761424 | |
| MESH:D000743 | Anemia, Hemolytic | Phenacetin | 6.22 | 17698508 1949026 17082564 | |
| MESH:D000743 | Anemia, Hemolytic | Quercetin | 6.22 | 17084956 | |
| MESH:D018798 | Anemia, Iron-Deficiency | Vitamin A | 3.50 | 16960172 | |
| MESH:D000755 | Anemia, Sickle Cell | Aspartame | 4.67 | 11372003 | |
| MESH:D000787 | Angina Pectoris | Drugs, Chinese Herbal | 3.98 | 11477813 | |
| MESH:D000799 | Angioedema | Acetaminophen | 2.40 | 10982225 | |
| MESH:D000853 | Anophthalmos | Ethanol | 3.41 | 15513904 | |
| MESH:D000860 | Anoxia | Zinc Sulfate | 3.60 | 7265320 | |
| MESH:D000987 | Antisocial Personality Disorder | Testosterone | 4.40 | 7506515 | |
| MESH:D001004 | Anus Diseases | Drugs, Chinese Herbal | 4.51 | 15043669 | |
| MESH:D001008 | Anxiety Disorders | Ethanol | 4.91 | 11141031 | |
| MESH:D001008 | Anxiety Disorders | vinclozolin | 4.91 | 19015723 | |
| MESH:D001014 | Aortic Aneurysm | Indomethacin | 3.46 | 10231640 | |
| MESH:D017544 | Aortic Aneurysm, Abdominal | Benzo(a)pyrene | 7.05 | 19183758 | |
| MESH:D017544 | Aortic Aneurysm, Abdominal | Indomethacin | 7.05 | 10388637 | |
| MESH:D020261 | Arsenic Poisoning | Arsenic | 2.27 | 12569548 18414634 16251483 16835338 | |
| MESH:D001161 | Arteriosclerosis | Dietary Fats | 2.51 | 15238619 | |
| MESH:D018771 | Arthralgia | Indomethacin | 3.71 | 2160914 | |
| MESH:D001169 | Arthritis, Experimental | Dexamethasone | 8.67 | 17659584 | |
| MESH:D001169 | Arthritis, Experimental | Plant Extracts | 8.67 | 14686799 | |
| MESH:D001169 | Arthritis, Experimental | resveratrol | 8.67 | 17115116 | |
| MESH:D001169 | Arthritis, Experimental | Tretinoin | 8.67 | 16412693 | |
| MESH:D015210 | Arthritis, Gouty | Drugs, Chinese Herbal | 4.31 | 19655406 | |
| MESH:D001172 | Arthritis, Rheumatoid | Aspartame | 6.91 | 10777254 | |
| MESH:D001172 | Arthritis, Rheumatoid | Curcumin | 6.91 | 16807698 | |
| MESH:D001172 | Arthritis, Rheumatoid | Indomethacin | 6.91 | 11248219 | |
| MESH:D001172 | Arthritis, Rheumatoid | Ozone | 6.91 | 15570426 | |
| MESH:D001172 | Arthritis, Rheumatoid | Tretinoin | 6.91 | 16292516 | |
| MESH:D001249 | Asthma | Acetaldehyde | 8.92 | 9600491 | |
| MESH:D001249 | Asthma | epigallocatechin gallate | 8.92 | 16516891 | |
| MESH:D001249 | Asthma | Ozone | 8.92 | 17854713 16373670 | |
| MESH:D001249 | Asthma | Theophylline | 8.92 | 12113382 9701106 | |
| MESH:D001249 | Asthma | Tretinoin | 8.92 | 16456186 | |
| MESH:D001249 | Asthma | Vitamin A | 8.92 | 16732791 | |
| MESH:D055963 | Asthma, Aspirin-Induced | Aspirin | 3.44 | 20485159 12372130 | |
| MESH:D001260 | Ataxia Telangiectasia | Quercetin | 3.54 | 15336622 | |
| MESH:D050197 | Atherosclerosis | Arsenic | 12.03 | 19371607 12928151 | |
| MESH:D050197 | Atherosclerosis | Curcumin | 12.03 | 18704882 | |
| MESH:D050197 | Atherosclerosis | mangiferin | 12.03 | 18450471 | |
| MESH:D050197 | Atherosclerosis | Methylcholanthrene | 12.03 | 11922910 | |
| MESH:D050197 | Atherosclerosis | Phenytoin | 12.03 | 15136057 | |
| MESH:D050197 | Atherosclerosis | resveratrol | 12.03 | 16873680 17967414 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 2.67 | 18445737 | |
| MESH:D001321 | Autistic Disorder | Arachidonic Acid | 2.67 | 18582451 | |
| MESH:D001321 | Autistic Disorder | Choline | 2.67 | 16818868 | |
| MESH:D001321 | Autistic Disorder | Docosahexaenoic Acids | 2.67 | 18582451 | |
| MESH:D001321 | Autistic Disorder | Glutathione | 2.67 | 18929414 19267885 16917939 19056591 | |
| MESH:D001321 | Autistic Disorder | Linoleic Acid | 2.67 | 18582451 | |
| MESH:D001321 | Autistic Disorder | S-Adenosylmethionine | 2.67 | 16917939 19056591 | |
| MESH:D001327 | Autoimmune Diseases | Curcumin | 10.13 | 19761891 | |
| MESH:D001327 | Autoimmune Diseases | epigallocatechin gallate | 10.13 | 19761891 | |
| MESH:D001327 | Autoimmune Diseases | Quercetin | 10.13 | 19761891 | |
| MESH:D001471 | Barrett Esophagus | Tretinoin | 3.01 | 16935849 | |
| MESH:D001477 | Bartter Syndrome | Indomethacin | 3.57 | 10684365 | |
| MESH:D001649 | Bile Duct Diseases | bromodichloromethane | 5.77 | 8717228 | |
| MESH:D001661 | Biliary Tract Neoplasms | Vinyl Chloride | 5.40 | 11024202 | |
| MESH:D001778 | Blood Coagulation Disorders | arsenic trioxide | 15.02 | 16206674 | |
| MESH:D001778 | Blood Coagulation Disorders | Omeprazole | 15.02 | 19483382 | |
| MESH:D001778 | Blood Coagulation Disorders | Tetrachlorodibenzodioxin | 15.02 | 12125929 | |
| MESH:D001778 | Blood Coagulation Disorders | Thioacetamide | 15.02 | 19483382 | |
| MESH:D001778 | Blood Coagulation Disorders | Tretinoin | 15.02 | 16206674 16197459 | |
| MESH:D001836 | Body Weight Changes | 2-cresol | 12.30 | 12820538 | |
| MESH:D001836 | Body Weight Changes | 2-xylene | 12.30 | 7457028 | |
| MESH:D001836 | Body Weight Changes | Tetrachlorodibenzodioxin | 12.30 | 15340226 | |
| MESH:D001848 | Bone Diseases, Developmental | Tetrachlorodibenzodioxin | 1.67 | 15746008 | |
| MESH:D001851 | Bone Diseases, Metabolic | Ginkgo biloba extract 761 | 4.91 | 19356626 | |
| MESH:D001855 | Bone Marrow Diseases | Benzene | 3.78 | 16183116 | |
| MESH:D001859 | Bone Neoplasms | Phenol | 3.86 | 10556009 | |
| MESH:D001862 | Bone Resorption | Drugs, Chinese Herbal | 5.84 | 9881647 | |
| MESH:D001862 | Bone Resorption | mangiferin | 5.84 | 9881647 | |
| MESH:D001913 | Bowen's Disease | Phenol | 4.30 | 19293009 | |
| MESH:D001929 | Brain Edema | Indomethacin | 3.58 | 11481608 | |
| MESH:D020201 | Brain Hemorrhage, Traumatic | Progesterone | 3.88 | 17868700 | |
| MESH:D001930 | Brain Injuries | Progesterone | 2.86 | 15845082 15380490 15665606 | |
| MESH:D002545 | Brain Ischemia | Curcumin | 16.99 | 16770732 | |
| MESH:D002545 | Brain Ischemia | Indomethacin | 16.99 | 12524144 | |
| MESH:D002545 | Brain Ischemia | Plant Extracts | 16.99 | 16041641 | |
| MESH:D002545 | Brain Ischemia | puerarin | 16.99 | 16041641 | |
| MESH:D002545 | Brain Ischemia | resveratrol | 16.99 | 17600658 | |
| MESH:D001932 | Brain Neoplasms | 1,3-butadiene | 13.81 | 16860786 | |
| MESH:D001932 | Brain Neoplasms | Acrylonitrile | 13.81 | 12562636 | |
| MESH:D001932 | Brain Neoplasms | Aspirin | 13.81 | 15481559 | |
| MESH:D001932 | Brain Neoplasms | Curcumin | 13.81 | 17596214 | |
| MESH:D001932 | Brain Neoplasms | Vinyl Chloride | 13.81 | 12562636 | |
| MESH:D001943 | Breast Neoplasms | 1,3-butadiene | 32.95 | 12165863 11921183 | |
| MESH:D001943 | Breast Neoplasms | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 32.95 | 20146248 | |
| MESH:D001943 | Breast Neoplasms | Acrylamide | 32.95 | 18183576 16253758 | |
| MESH:D001943 | Breast Neoplasms | allyl sulfide | 32.95 | 17125941 | |
| MESH:D001943 | Breast Neoplasms | Androgens | 32.95 | 17018787 | |
| MESH:D001943 | Breast Neoplasms | Ascorbic Acid | 32.95 | 16443354 | |
| MESH:D001943 | Breast Neoplasms | Aspirin | 32.95 | 15161893 | |
| MESH:D001943 | Breast Neoplasms | Benzene | 32.95 | 11921183 17162533 | |
| MESH:D001943 | Breast Neoplasms | Benzo(a)pyrene | 32.95 | 20146248 17474063 | |
| MESH:D001943 | Breast Neoplasms | Curcumin | 32.95 | 18462866 18593918 16243823 19250217 | |
| MESH:D001943 | Breast Neoplasms | Deferoxamine | 32.95 | 15993339 | |
| MESH:D001943 | Breast Neoplasms | Dietary Fats | 32.95 | 20435547 | |
| MESH:D001943 | Breast Neoplasms | Diethylnitrosamine | 32.95 | 17474063 | |
| MESH:D001943 | Breast Neoplasms | Disulfiram | 32.95 | 17026967 | |
| MESH:D001943 | Breast Neoplasms | Estradiol | 32.95 | 16675129 12948864 17018787 14630087 18497071 17261762 19861407 17289903 | |
| MESH:D001943 | Breast Neoplasms | Ethylene Dibromide | 32.95 | 11921183 | |
| MESH:D001943 | Breast Neoplasms | Grape Seed Proanthocyanidins | 32.95 | 20146248 | |
| MESH:D001943 | Breast Neoplasms | Hexachlorobenzene | 32.95 | 15061365 12709520 | |
| MESH:D001943 | Breast Neoplasms | Indomethacin | 32.95 | 17401462 | |
| MESH:D001943 | Breast Neoplasms | Lindane | 32.95 | 14688026 | |
| MESH:D001943 | Breast Neoplasms | Methylcholanthrene | 32.95 | 17474063 | |
| MESH:D001943 | Breast Neoplasms | Methylene Chloride | 32.95 | 15986119 | |
| MESH:D001943 | Breast Neoplasms | Nitric Oxide | 32.95 | 15631943 | |
| MESH:D001943 | Breast Neoplasms | ochratoxin A | 32.95 | 11921183 | |
| MESH:D001943 | Breast Neoplasms | Parathion | 32.95 | 12762645 | |
| MESH:D001943 | Breast Neoplasms | Progesterone | 32.95 | 17614352 15562024 16175315 | |
| MESH:D001943 | Breast Neoplasms | Quercetin | 32.95 | 18628248 | |
| MESH:D001943 | Breast Neoplasms | resveratrol | 32.95 | 17651959 17534123 16393696 | |
| MESH:D001943 | Breast Neoplasms | Styrene | 32.95 | 15986119 | |
| MESH:D001943 | Breast Neoplasms | Testosterone | 32.95 | 17261762 | |
| MESH:D001943 | Breast Neoplasms | Tetrachlorodibenzodioxin | 32.95 | 20435547 | |
| MESH:D001943 | Breast Neoplasms | Tetrachloroethylene | 32.95 | 15986119 | |
| MESH:D001943 | Breast Neoplasms | Tretinoin | 32.95 | 16443354 16873071 16166294 | |
| MESH:D001943 | Breast Neoplasms | Trichloroethylene | 32.95 | 15986119 | |
| MESH:D016535 | Bronchial Hyperreactivity | Ozone | 2.49 | 16777450 15516495 17626835 18315731 18417511 19059883 14754758 | |
| MESH:D001997 | Bronchopulmonary Dysplasia | Tretinoin | 8.27 | 16813970 | |
| MESH:D001997 | Bronchopulmonary Dysplasia | Vitamin A | 8.27 | 17377406 17426644 | |
| MESH:D002051 | Burkitt Lymphoma | arsenic trioxide | 2.97 | 11589617 | |
| MESH:D002056 | Burns | Ethanol | 6.73 | 16374292 | |
| MESH:D002056 | Burns | Indomethacin | 6.73 | 10459503 | |
| MESH:D002057 | Burns, Chemical | Plant Extracts | 3.89 | 9625245 | |
| MESH:D002100 | Cachexia | Indomethacin | 7.66 | 11239499 16537180 15141370 15625704 | |
| MESH:D002100 | Cachexia | Ozone | 7.66 | 16183385 | |
| MESH:D002105 | Cadmium Poisoning | Quercetin | 4.08 | 16962696 | |
| MESH:D002177 | Candidiasis | Disulfiram | 4.42 | 15325261 | |
| MESH:D002181 | Candidiasis, Vulvovaginal | Estradiol | 3.03 | 16111702 | |
| MESH:D002252 | Carbon Tetrachloride Poisoning | Carbon Tetrachloride | 5.91 | 15721981 18705752 15700767 16124888 16227642 16097048 15673190 16011737 10355542 16050911 3786805 16192424 | |
| MESH:D002252 | Carbon Tetrachloride Poisoning | Oleanolic Acid | 5.91 | 10355542 | |
| MESH:D002276 | Carcinoid Tumor | Streptozocin | 4.15 | 16051944 | |
| MESH:D002277 | Carcinoma | 2,6-xylidine | 24.55 | 10463772 10945294 11442016 | |
| MESH:D002277 | Carcinoma | 4-dichlorobenzene | 24.55 | 12748734 | |
| MESH:D002277 | Carcinoma | Curcumin | 24.55 | 18593918 | |
| MESH:D002277 | Carcinoma | Dimethylnitrosamine | 24.55 | 19555203 | |
| MESH:D002277 | Carcinoma | Disulfiram | 24.55 | 17026967 | |
| MESH:D002277 | Carcinoma | Methylcholanthrene | 24.55 | 10545420 | |
| MESH:D002277 | Carcinoma | N-methyl-N-nitrosoaniline | 24.55 | 6402317 | |
| MESH:D002277 | Carcinoma | Tetrachlorodibenzodioxin | 24.55 | 16835633 | |
| MESH:D002280 | Carcinoma, Basal Cell | Arsenic | 2.58 | 17687452 15504454 | |
| MESH:D018236 | Carcinoma, Embryonal | Tretinoin | 3.70 | 16168501 | |
| MESH:D006528 | Carcinoma, Hepatocellular | 2-Acetylaminofluorene | 41.16 | 10737359 17761372 6705139 3084413 3581430 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 41.16 | 3084413 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Aflatoxin B1 | 41.16 | 21507988 12907637 12619106 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Arsenic | 41.16 | 17306315 16507464 | |
| MESH:D006528 | Carcinoma, Hepatocellular | arsenic trioxide | 41.16 | 15553829 11135700 14691202 15073043 16217749 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Carbon Tetrachloride | 41.16 | 18788625 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Diethylnitrosamine | 41.16 | 19394651 20935162 18971187 18788625 21159647 16569478 11831363 16878318 20084675 17761372 16779866 17173139 18665156 3084413 18785209 19171122 19822196 16288022 3581430 17978847 19519916 10672840 19418558 19539802 20512989 18210153 19335982 19052882 20007298 17138121 20432363 20514400 20524982 19701751 18056438 17055752 10737359 19919837 18691550 18506893 16681979 17428255 16540662 18393292 18494052 16807293 19107877 16328049 20214788 16502159 19208518 17162532 16698587 19383236 18978308 16830150 16935385 20101231 20727157 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Estradiol | 41.16 | 16924424 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Estrogens | 41.16 | 15341023 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Ethanol | 41.16 | 18788625 15763234 15289165 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Indomethacin | 41.16 | 16391822 | |
| MESH:D006528 | Carcinoma, Hepatocellular | N-nitrosomorpholine | 41.16 | 15010824 8364915 16935385 19335982 15543204 1967229 19383236 11509945 9466558 9311599 2885971 1917145 10629087 9029167 1701930 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Phenobarbital | 41.16 | 1701930 6705139 20007298 17173139 20935162 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Plant Extracts | 41.16 | 18834353 | |
| MESH:D006528 | Carcinoma, Hepatocellular | pyridine | 41.16 | 10696769 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Quercetin | 41.16 | 12508355 19519916 | |
| MESH:D006528 | Carcinoma, Hepatocellular | quinoline | 41.16 | 598648 | |
| MESH:D006528 | Carcinoma, Hepatocellular | resveratrol | 41.16 | 19321006 16227395 | |
| MESH:D006528 | Carcinoma, Hepatocellular | sodium arsenite | 41.16 | 15276417 17306315 16507464 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Thioacetamide | 41.16 | 17997003 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Tretinoin | 41.16 | 1917145 | |
| MESH:D006528 | Carcinoma, Hepatocellular | vinyl carbamate | 41.16 | 12371669 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Vinyl Chloride | 41.16 | 12828392 12958735 10699891 15289165 | |
| MESH:D018827 | Carcinoma, Lewis Lung | Indomethacin | 6.70 | 11053908 | |
| MESH:D018827 | Carcinoma, Lewis Lung | resveratrol | 6.70 | 16675471 | |
| MESH:D018276 | Carcinoma, Medullary | Indomethacin | 3.91 | 14736730 18791128 11352223 | |
| MESH:D002289 | Carcinoma, Non-Small-Cell Lung | marker/mechanism | 16142352 | ||
| MESH:D002289 | Carcinoma, Non-Small-Cell Lung | Curcumin | 4.68 | 18414057 | |
| MESH:D002289 | Carcinoma, Non-Small-Cell Lung | Disulfiram | 4.68 | 17026967 | |
| MESH:D002289 | Carcinoma, Non-Small-Cell Lung | vinyl carbamate | 4.68 | 16247446 | |
| MESH:D021441 | Carcinoma, Pancreatic Ductal | Quercetin | 3.54 | 17234771 | |
| MESH:D002291 | Carcinoma, Papillary | arsenic trioxide | 3.42 | 19014326 | |
| MESH:D002292 | Carcinoma, Renal Cell | ferric nitrilotriacetate | 5.77 | 8340253 | |
| MESH:D002292 | Carcinoma, Renal Cell | Indomethacin | 5.77 | 17341418 | |
| MESH:D002292 | Carcinoma, Renal Cell | N-nitrosomorpholine | 5.77 | 1429202 7921415 | |
| MESH:D018288 | Carcinoma, Small Cell | arsenic trioxide | 2.80 | 12490120 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Arsenic | 23.26 | 18922899 17687452 15504454 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Benzo(a)pyrene | 23.26 | 20419170 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Curcumin | 23.26 | 18462866 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Dimethylnitrosamine | 23.26 | 16033868 | |
| MESH:D002294 | Carcinoma, Squamous Cell | erythritol anhydride | 23.26 | 10925838 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Glutathione | 23.26 | 17015178 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Indomethacin | 23.26 | 12636206 15482327 | |
| MESH:D002294 | Carcinoma, Squamous Cell | N-methyl-N-benzylnitrosamine | 23.26 | 12222751 | |
| MESH:D002294 | Carcinoma, Squamous Cell | resveratrol | 23.26 | 16227395 | |
| MESH:D002294 | Carcinoma, Squamous Cell | sodium arsenite | 23.26 | 18572023 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Tetradecanoylphorbol Acetate | 23.26 | 18922899 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Tretinoin | 23.26 | 16096774 16051514 | |
| MESH:D002295 | Carcinoma, Transitional Cell | Arsenic | 2.79 | 18640142 | |
| MESH:D006332 | Cardiomegaly | Ethanol | 7.90 | 19332462 | |
| MESH:D006332 | Cardiomegaly | Plant Extracts | 7.90 | 17645561 | |
| MESH:D006332 | Cardiomegaly | Quercetin | 7.90 | 19794523 | |
| MESH:D006332 | Cardiomegaly | Tetrachlorodibenzodioxin | 7.90 | 18670907 18850075 16120746 | |
| MESH:D002310 | Cardiomyopathy, Alcoholic | Acetaldehyde | 5.02 | 10525098 | |
| MESH:D002318 | Cardiovascular Diseases | 4-cresol | 5.95 | 20430946 | |
| MESH:D002318 | Cardiovascular Diseases | Arsenic | 5.95 | 17938729 15738583 19152805 | |
| MESH:D002318 | Cardiovascular Diseases | resveratrol | 5.95 | 15458977 | |
| MESH:D002340 | Carotid Artery Diseases | Arsenic | 3.02 | 16973168 18022660 | |
| MESH:D002375 | Catalepsy | Fluphenazine | 5.10 | 1977408 | |
| MESH:D002386 | Cataract | Acetaminophen | 9.07 | 10977129 | |
| MESH:D002386 | Cataract | Disulfiram | 9.07 | 17936468 15003327 | |
| MESH:D002386 | Cataract | Mirex | 9.07 | 6723604 | |
| MESH:D002386 | Cataract | Tretinoin | 9.07 | 17460283 | |
| MESH:D002418 | Cattle Diseases | Acrylamide | 4.02 | 12510666 | |
| MESH:D002471 | Cell Transformation, Neoplastic | 2,6-xylidine | 14.58 | 8243401 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Azoxymethane | 14.58 | 15705887 18075178 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Cyclosporine | 14.58 | 12371664 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Diethylnitrosamine | 14.58 | 17174075 21159647 7505956 2727394 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Estradiol | 14.58 | 18566989 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Methylcholanthrene | 14.58 | 16192471 | |
| MESH:D002471 | Cell Transformation, Neoplastic | sodium arsenite | 14.58 | 19524636 20056578 | |
| MESH:D002493 | Central Nervous System Diseases | Phenobarbital | 7.01 | 4080065 | |
| MESH:D002493 | Central Nervous System Diseases | Phenytoin | 7.01 | 4080065 | |
| MESH:D002547 | Cerebral Palsy | Toluene | 4.41 | 9294310 | |
| MESH:D018290 | Cervical Intraepithelial Neoplasia | Tretinoin | 3.15 | 16129372 | |
| MESH:D002637 | Chest Pain | Omeprazole | 7.77 | 15447763 | |
| MESH:D002637 | Chest Pain | Theophylline | 7.77 | 15238202 | |
| MESH:D002659 | Child Development Disorders, Pervasive | Testosterone | 2.95 | 20678186 | |
| MESH:D015362 | Child Nutrition Disorders | Vitamin A | 4.03 | 16153327 | |
| MESH:D018281 | Cholangiocarcinoma | Diethylnitrosamine | 8.71 | 19052882 | |
| MESH:D018281 | Cholangiocarcinoma | Tetrachlorodibenzodioxin | 8.71 | 16835633 | |
| MESH:D018281 | Cholangiocarcinoma | Thioacetamide | 8.71 | 18291259 | |
| MESH:D002761 | Cholangitis | 1-Naphthylisothiocyanate | 4.74 | 12912871 | |
| MESH:D002764 | Cholecystitis | Indomethacin | 3.71 | 11181007 | |
| MESH:D002779 | Cholestasis | 1-Naphthylisothiocyanate | 9.68 | 12927374 19486331 18590720 15913567 7624871 15500046 16629650 18164287 | |
| MESH:D002779 | Cholestasis | Cyclosporine | 9.68 | 19486331 | |
| MESH:D002779 | Cholestasis | Nitric Oxide | 9.68 | 16919318 | |
| MESH:D002779 | Cholestasis | Vitamin A | 9.68 | 16175620 | |
| MESH:D002780 | Cholestasis, Intrahepatic | 1-Naphthylisothiocyanate | 4.40 | 19407337 10220858 | |
| OMIM:601042 | CHOREOATHETOSIS/SPASTICITY, EPISODIC | Phenytoin | 4.43 | 11748493 | |
| MESH:D002822 | Choriocarcinoma | Tretinoin | 3.70 | 16461808 | |
| MESH:D016770 | Ciliophora Infections | Quinacrine | 5.02 | 12113305 | |
| MESH:D002971 | Cleft Lip | Ethanol | 4.60 | 15513904 | |
| MESH:D002971 | Cleft Lip | Phenytoin | 4.60 | 2227380 | |
| MESH:D002972 | Cleft Palate | Ethanol | 14.44 | 15513904 | |
| MESH:D002972 | Cleft Palate | Phenytoin | 14.44 | 6856622 10789828 2227380 1687470 6862529 3877104 | |
| MESH:D002972 | Cleft Palate | Tetrachlorodibenzodioxin | 14.44 | 8697196 15668235 15340226 12621046 16354765 | |
| MESH:D002972 | Cleft Palate | Tretinoin | 14.44 | 9407595 | |
| MESH:D002972 | Cleft Palate | triadimefon | 14.44 | 16781842 | |
| MESH:D002972 | Cleft Palate | Urethane | 14.44 | 12810352 | |
| MESH:D002972 | Cleft Palate | Vitamin A | 14.44 | 16054864 | |
| MESH:D019970 | Cocaine-Related Disorders | Disulfiram | 4.32 | 19462300 | |
| MESH:D003092 | Colitis | Curcumin | 8.10 | 16782535 18200517 16804969 | |
| MESH:D003092 | Colitis | resveratrol | 8.10 | 16474422 | |
| MESH:D003092 | Colitis | Tretinoin | 8.10 | 17035595 | |
| MESH:D003093 | Colitis, Ulcerative | phenethyl isothiocyanate | 2.95 | 20423518 | |
| MESH:D003103 | Coloboma | Curcumin | 6.89 | 18809619 | |
| MESH:D003103 | Coloboma | Phenytoin | 6.89 | 9212184 | |
| MESH:D003110 | Colonic Neoplasms | Aspirin | 14.26 | 12411196 | |
| MESH:D003110 | Colonic Neoplasms | Azoxymethane | 14.26 | 16818512 12189186 16293270 15824018 19056647 14668109 15705887 | |
| MESH:D003110 | Colonic Neoplasms | bromodichloromethane | 14.26 | 14668109 | |
| MESH:D003110 | Colonic Neoplasms | Curcumin | 14.26 | 19359593 16340194 | |
| MESH:D003110 | Colonic Neoplasms | Dexamethasone | 14.26 | 15824018 | |
| MESH:D003110 | Colonic Neoplasms | Indomethacin | 14.26 | 15936596 15625704 11260862 15786552 15963497 15637740 | |
| MESH:D003110 | Colonic Neoplasms | polyphenols | 14.26 | 16293270 | |
| MESH:D003110 | Colonic Neoplasms | Quercetin | 14.26 | 15741050 11134977 19056647 19440933 17148506 16640504 17191121 | |
| MESH:D003110 | Colonic Neoplasms | resveratrol | 14.26 | 16338953 | |
| MESH:D003110 | Colonic Neoplasms | Vitamin A | 14.26 | 16267017 17219422 | |
| MESH:D015179 | Colorectal Neoplasms | arsenic trioxide | 3.81 | 20501625 | |
| MESH:D015179 | Colorectal Neoplasms | Aspirin | 3.81 | 17047198 | |
| MESH:D015179 | Colorectal Neoplasms | Azoxymethane | 3.81 | 10416599 11076880 | |
| MESH:D015179 | Colorectal Neoplasms | Indomethacin | 3.81 | 12606626 11197048 17054584 18059344 | |
| MESH:D015179 | Colorectal Neoplasms | Quercetin | 3.81 | 18095365 18852136 | |
| MESH:D015179 | Colorectal Neoplasms | resveratrol | 3.81 | 16550006 | |
| MESH:D003128 | Coma | Ginkgo biloba extract 761 | 4.77 | 10836866 | |
| MESH:D003139 | Common Cold | Ascorbic Acid | 4.02 | 17323712 | |
| MESH:D000013 | Congenital Abnormalities | Phenytoin | 5.14 | 10627286 | |
| MESH:D000013 | Congenital Abnormalities | Tetrachlorodibenzodioxin | 5.14 | 14669216 17141729 | |
| MESH:D016510 | Corneal Neovascularization | Curcumin | 3.49 | 18497527 | |
| MESH:D003327 | Coronary Disease | resveratrol | 2.66 | 16507316 | |
| MESH:D023903 | Coronary Restenosis | arsenic trioxide | 2.81 | 12609071 | |
| MESH:D018352 | Coronavirus Infections | Indomethacin | 4.26 | 17302372 | |
| MESH:D019465 | Craniofacial Abnormalities | arsenic trioxide | 15.46 | 10525206 | |
| MESH:D019465 | Craniofacial Abnormalities | Benzene | 15.46 | 15643154 | |
| MESH:D019465 | Craniofacial Abnormalities | decamethrin | 15.46 | 19861644 | |
| MESH:D019465 | Craniofacial Abnormalities | Dexamethasone | 15.46 | 17728286 | |
| MESH:D019465 | Craniofacial Abnormalities | Ethanol | 15.46 | 15451040 11198716 15513904 19302082 10194807 15451039 11873399 | |
| MESH:D019465 | Craniofacial Abnormalities | ochratoxin A | 15.46 | 20036863 | |
| MESH:D019465 | Craniofacial Abnormalities | Phenytoin | 15.46 | 19952982 8986270 9212184 | |
| MESH:D019465 | Craniofacial Abnormalities | Reactive Oxygen Species | 15.46 | 15736158 | |
| MESH:D019465 | Craniofacial Abnormalities | Tetrachlorodibenzodioxin | 15.46 | 20055451 15322242 10048152 | |
| MESH:D019465 | Craniofacial Abnormalities | Toluene | 15.46 | 9294310 | |
| MESH:D019465 | Craniofacial Abnormalities | Tretinoin | 15.46 | 16925845 17551590 9142499 10589399 9211117 14991402 9224671 8800419 9125849 9664655 | |
| MESH:D019465 | Craniofacial Abnormalities | triadimefon | 15.46 | 15834900 16875885 | |
| MESH:D019465 | Craniofacial Abnormalities | Vitamin A | 15.46 | 10992263 | |
| MESH:D016638 | Critical Illness | Androgens | 8.94 | 16670151 | |
| MESH:D016638 | Critical Illness | Estrogens | 8.94 | 16670151 | |
| MESH:D003456 | Cryptorchidism | vinclozolin | 2.96 | 14966744 | |
| MESH:D003457 | Cryptosporidiosis | mangiferin | 4.40 | 16547730 | |
| MESH:D003550 | Cystic Fibrosis | Docosahexaenoic Acids | 5.07 | 19747007 | |
| MESH:D003550 | Cystic Fibrosis | Glutathione | 5.07 | 19747007 | |
| MESH:D003643 | Death | Toluene | 4.21 | 6431079 | |
| MESH:D016757 | Death, Sudden, Cardiac | arsenic trioxide | 6.79 | 15213294 | |
| MESH:D016757 | Death, Sudden, Cardiac | Thioridazine | 6.79 | 20210726 | |
| MESH:D003704 | Dementia | Thioridazine | 4.26 | 11575062 | |
| MESH:D015140 | Dementia, Vascular | Nitric Oxide | 4.52 | 17556102 | |
| MESH:D003731 | Dental Caries | Aspartame | 5.46 | 8955999 | |
| MESH:D003866 | Depressive Disorder | Desipramine | 3.99 | 3690436 15014590 | |
| MESH:D003872 | Dermatitis | 3-xylene | 7.21 | 12717741 15902427 | |
| MESH:D003872 | Dermatitis | Benzene | 7.21 | 15902427 | |
| MESH:D017449 | Dermatitis, Allergic Contact | Aspartame | 6.00 | 14996049 | |
| MESH:D017449 | Dermatitis, Allergic Contact | Dexamethasone | 6.00 | 12438553 | |
| MESH:D017449 | Dermatitis, Allergic Contact | Maneb | 6.00 | 8807224 | |
| MESH:D017449 | Dermatitis, Allergic Contact | Propolis | 6.00 | 16191021 | |
| MESH:D009783 | Dermatitis, Occupational | Maneb | 7.06 | 8807224 | |
| MESH:D009783 | Dermatitis, Occupational | Vinyl Chloride | 7.06 | 10870345 | |
| MESH:D002658 | Developmental Disabilities | Choline | 3.57 | 16818868 | |
| MESH:D003920 | Diabetes Mellitus | Streptozocin | 3.47 | 16285004 | |
| MESH:D003921 | Diabetes Mellitus, Experimental | Alloxan | 12.92 | 17034923 | |
| MESH:D003921 | Diabetes Mellitus, Experimental | mangiferin | 12.92 | 12093613 19028559 | |
| MESH:D003921 | Diabetes Mellitus, Experimental | Quercetin | 12.92 | 19496084 | |
| MESH:D003921 | Diabetes Mellitus, Experimental | resveratrol | 12.92 | 16873680 | |
| MESH:D003921 | Diabetes Mellitus, Experimental | Streptozocin | 12.92 | 18603373 17874149 15862027 15831366 7637645 19960420 2177838 8740154 19496084 18715473 12446591 12083368 16286809 12644472 15298345 19298542 12093613 19586609 1374869 16684804 17442507 6379147 11260395 11055810 | |
| MESH:D003922 | Diabetes Mellitus, Type 1 | Streptozocin | 3.73 | 18603373 | |
| MESH:D003922 | Diabetes Mellitus, Type 1 | Vitamin A | 3.73 | 16506275 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Ascorbic Acid | 10.45 | 16506275 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Curcumin | 10.45 | 18403477 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Diethylnitrosamine | 10.45 | 20387270 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | epigallocatechin gallate | 10.45 | 16988119 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | mangiferin | 10.45 | 11315760 9881663 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Streptozocin | 10.45 | 19586609 19647726 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Tetrachlorodibenzodioxin | 10.45 | 17107852 | |
| MESH:D058065 | Diabetic Cardiomyopathies | Streptozocin | 4.29 | 16025228 | |
| MESH:D003928 | Diabetic Nephropathies | Curcumin | 18.66 | 18204486 | |
| MESH:D003928 | Diabetic Nephropathies | Estradiol | 18.66 | 19279558 | |
| MESH:D003928 | Diabetic Nephropathies | mangiferin | 18.66 | 19706694 19960420 | |
| MESH:D003928 | Diabetic Nephropathies | Plant Extracts | 18.66 | 19706694 | |
| MESH:D003928 | Diabetic Nephropathies | resveratrol | 18.66 | 16286809 | |
| MESH:D003928 | Diabetic Nephropathies | Streptozocin | 18.66 | 19682444 19960420 | |
| MESH:D003929 | Diabetic Neuropathies | Progesterone | 3.09 | 17187935 | |
| MESH:D003930 | Diabetic Retinopathy | Streptozocin | 4.04 | 17662242 | |
| MESH:D003967 | Diarrhea | Dexamethasone | 3.91 | 7237001 | |
| MESH:D003967 | Diarrhea | Indomethacin | 3.91 | 7237001 7907874 | |
| OMIM:607208 | DRAVET SYNDROME | Phenytoin | 3.98 | 11748493 | |
| MESH:D003875 | Drug Eruptions | Phenytoin | 4.09 | 15024534 | |
| MESH:D056486 | Drug-Induced Liver Injury | marker/mechanism | 12668988 16770646 | ||
| MESH:D056486 | Drug-Induced Liver Injury | 1,1-dichloroethane | 82.19 | 2862719 | |
| MESH:D056486 | Drug-Induced Liver Injury | 1,2,4-trichlorobenzene | 82.19 | 10092053 | |
| MESH:D056486 | Drug-Induced Liver Injury | 1,2-dichloroethylene | 82.19 | 7497910 | |
| MESH:D056486 | Drug-Induced Liver Injury | 1-Naphthylisothiocyanate | 82.19 | 7624871 18289764 17522070 20133375 | |
| MESH:D056486 | Drug-Induced Liver Injury | 2,2-dichloro-1,1,1-trifluoroethane | 82.19 | 12451447 7676453 12919722 12570398 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 82.19 | 12958197 12594235 19739265 12392966 14986274 16485898 14725611 19420014 11834606 15968718 16781746 18713872 16227642 16393943 16081117 11743745 19416960 15619225 18071297 10774834 11461765 17562736 17522070 11739529 11421492 19164858 16109766 2444490 12153990 19085960 14550746 19370779 10663392 19923254 17906064 16177239 10915739 12705907 11529661 12540782 11287661 | |
| MESH:D056486 | Drug-Induced Liver Injury | allyl alcohol | 82.19 | 7440962 | |
| MESH:D056486 | Drug-Induced Liver Injury | allyl sulfide | 82.19 | 15950962 | |
| MESH:D056486 | Drug-Induced Liver Injury | bicyclol | 82.19 | 15998439 | |
| MESH:D056486 | Drug-Induced Liver Injury | bromobenzene | 82.19 | 12628495 10092053 | |
| MESH:D056486 | Drug-Induced Liver Injury | Carbon Tetrachloride | 82.19 | 16177239 19336974 3786805 11566570 3732212 6623471 19085960 15027814 16227642 7179309 7120509 6884620 15998439 10092053 21278145 2869522 9327722 17522070 10915739 7440962 15968718 4309450 | |
| MESH:D056486 | Drug-Induced Liver Injury | Chlorodiphenyl (54% Chlorine) | 82.19 | 17851650 | |
| MESH:D056486 | Drug-Induced Liver Injury | Chloroform | 82.19 | 6623471 3104120 2862719 7440962 6884620 17522070 7120509 3732212 | |
| MESH:D056486 | Drug-Induced Liver Injury | Chlorpromazine | 82.19 | 11461765 | |
| MESH:D056486 | Drug-Induced Liver Injury | Diethylnitrosamine | 82.19 | 19107877 | |
| MESH:D056486 | Drug-Induced Liver Injury | Dimethylformamide | 82.19 | 3732212 | |
| MESH:D056486 | Drug-Induced Liver Injury | Dimethylnitrosamine | 82.19 | 8172417 | |
| MESH:D056486 | Drug-Induced Liver Injury | Drugs, Chinese Herbal | 82.19 | 15027814 | |
| MESH:D056486 | Drug-Induced Liver Injury | Ethanol | 82.19 | 11566570 | |
| MESH:D056486 | Drug-Induced Liver Injury | Ethylene Dibromide | 82.19 | 2862719 | |
| MESH:D056486 | Drug-Induced Liver Injury | fumonisin B1 | 82.19 | 16221962 | |
| MESH:D056486 | Drug-Induced Liver Injury | gadolinium chloride | 82.19 | 12963478 | |
| MESH:D056486 | Drug-Induced Liver Injury | Halothane | 82.19 | 12919722 | |
| MESH:D056486 | Drug-Induced Liver Injury | Isoniazid | 82.19 | 17950035 16770646 14986274 | |
| MESH:D056486 | Drug-Induced Liver Injury | Ketoconazole | 82.19 | 18289764 | |
| MESH:D056486 | Drug-Induced Liver Injury | polyphenols | 82.19 | 19370779 | |
| MESH:D056486 | Drug-Induced Liver Injury | pyrazole | 82.19 | 12499123 | |
| MESH:D056486 | Drug-Induced Liver Injury | Silymarin | 82.19 | 14998559 | |
| MESH:D056486 | Drug-Induced Liver Injury | Tea | 82.19 | 19370779 | |
| MESH:D056486 | Drug-Induced Liver Injury | Tetrachlorodibenzodioxin | 82.19 | 20420201 | |
| MESH:D056486 | Drug-Induced Liver Injury | Thioacetamide | 82.19 | 12963478 | |
| MESH:D056486 | Drug-Induced Liver Injury | Trichloroethylene | 82.19 | 7120509 | |
| MESH:D056486 | Drug-Induced Liver Injury | trichloromethyl free radical | 82.19 | 2869522 | |
| MESH:D056486 | Drug-Induced Liver Injury | vinylidene chloride | 82.19 | 3697828 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 2.64 | 19426721 | |
| MESH:D004362 | Drug Toxicity | Tetrachlorodibenzodioxin | 1.61 | 11462148 | |
| MESH:D015352 | Dry Eye Syndromes | Vitamin A | 4.36 | 16146918 | |
| MESH:D004374 | Ductus Arteriosus, Patent | Indomethacin | 3.71 | 16326151 17190690 18446180 12774134 16133044 18043480 | |
| MESH:D004381 | Duodenal Ulcer | Curcumin | 7.62 | 17351913 | |
| MESH:D004381 | Duodenal Ulcer | Indomethacin | 7.62 | 17202747 17329845 11595431 17351913 11535926 17151854 17045617 11595415 16699067 10671773 11991626 | |
| MESH:D004381 | Duodenal Ulcer | Omeprazole | 7.62 | 17151854 16613094 21218061 15991576 | |
| MESH:D004409 | Dyskinesia, Drug-Induced | Desipramine | 4.74 | 3690436 | |
| MESH:D050171 | Dyslipidemias | Dietary Fats | 2.29 | 18367378 | |
| MESH:D004421 | Dystonia | Phenobarbital | 2.65 | 1851702 | |
| MESH:D020821 | Dystonic Disorders | Nicotine | 4.49 | 17881519 | |
| MESH:C538011 | Eales disease | Ascorbic Acid | 8.60 | 9068938 | |
| MESH:C538011 | Eales disease | Vitamin A | 8.60 | 9068938 | |
| MESH:D004480 | Ectromelia | Vitamin A | 4.36 | 16054864 | |
| MESH:D004485 | Eczema | Dexamethasone | 6.82 | 12438553 | |
| MESH:D004485 | Eczema | Methoxsalen | 6.82 | 16259964 | |
| MESH:D004487 | Edema | Arachidonic Acid | 21.81 | 15177302 7990266 11698051 9599246 16716910 9831321 | |
| MESH:D004487 | Edema | Aspirin | 21.81 | 17259670 | |
| MESH:D004487 | Edema | Dexamethasone | 21.81 | 19703484 | |
| MESH:D004487 | Edema | Indomethacin | 21.81 | 7990266 19703484 8273558 16100529 10653021 7907874 8985016 | |
| MESH:D004487 | Edema | perfluorooctanoic acid | 21.81 | 12083418 17259670 | |
| MESH:D004487 | Edema | Plant Extracts | 21.81 | 12787963 | |
| MESH:D004487 | Edema | resveratrol | 21.81 | 8985016 | |
| MESH:D004487 | Edema | Staurosporine | 21.81 | 8273558 | |
| MESH:D004487 | Edema | Tetrachlorodibenzodioxin | 21.81 | 12711302 11000095 | |
| MESH:D004487 | Edema | Tetradecanoylphorbol Acetate | 21.81 | 16716910 9599246 8273558 11698051 7812673 15177302 8113982 | |
| MESH:D004489 | Edema, Cardiac | Tetrachlorodibenzodioxin | 7.14 | 15322242 18230668 16714409 | |
| MESH:D004489 | Edema, Cardiac | Tretinoin | 7.14 | 18230668 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Phenytoin | 7.74 | 17654737 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Progesterone | 7.74 | 17692515 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | resveratrol | 7.74 | 17872969 | |
| MESH:D018159 | Endolymphatic Hydrops | Dimethyl Sulfoxide | 5.10 | 20641076 | |
| MESH:D016889 | Endometrial Neoplasms | Estradiol | 3.73 | 11473722 19148513 18566989 | |
| MESH:D016889 | Endometrial Neoplasms | Tretinoin | 3.73 | 16569247 | |
| MESH:D004715 | Endometriosis | Indomethacin | 7.81 | 15652904 | |
| MESH:D004715 | Endometriosis | Progesterone | 7.81 | 16134523 | |
| MESH:D004715 | Endometriosis | Tetrachlorodibenzodioxin | 7.81 | 9294722 10568697 | |
| MESH:D004719 | Endomyocardial Fibrosis | Plant Extracts | 4.22 | 15268973 | |
| MESH:D019446 | Endotoxemia | Indomethacin | 5.95 | 18509659 | |
| MESH:D019446 | Endotoxemia | Lipopolysaccharides | 5.95 | 15328337 15821434 17637181 | |
| MESH:D004751 | Enteritis | Indomethacin | 3.31 | 16328016 10567023 17763956 | |
| MESH:D020345 | Enterocolitis, Necrotizing | Indomethacin | 7.70 | 17980183 | |
| MESH:D020345 | Enterocolitis, Necrotizing | resveratrol | 7.70 | 17923197 | |
| MESH:D004802 | Eosinophilia | Indomethacin | 2.73 | 11298111 | |
| MESH:D004816 | Epidermal Necrolysis, Toxic | Phenytoin | 3.82 | 20235791 | |
| MESH:D004820 | Epidermolysis Bullosa | Phenytoin | 4.77 | 6251365 1399206 | |
| MESH:D004831 | Epilepsies, Myoclonic | Phenobarbital | 2.71 | 3659116 | |
| MESH:D004828 | Epilepsies, Partial | Phenobarbital | 5.60 | 3922381 11558140 | |
| MESH:D004828 | Epilepsies, Partial | Phenytoin | 5.60 | 17116037 11558140 | |
| MESH:D004827 | Epilepsy | Phenobarbital | 5.52 | 20417680 | |
| MESH:D004827 | Epilepsy | Phenytoin | 5.52 | 20417680 11434505 821787 | |
| MESH:D004827 | Epilepsy | Plant Extracts | 5.52 | 19439326 19700373 | |
| MESH:D004832 | Epilepsy, Absence | Phenobarbital | 2.30 | 6401628 | |
| MESH:D017029 | Epilepsy, Complex Partial | Phenobarbital | 7.01 | 7750514 | |
| MESH:D017029 | Epilepsy, Complex Partial | Phenytoin | 7.01 | 7750514 | |
| MESH:D004830 | Epilepsy, Tonic-Clonic | Phenobarbital | 6.15 | 3659116 | |
| MESH:D004830 | Epilepsy, Tonic-Clonic | Phenytoin | 6.15 | 3659116 | |
| MESH:D004892 | Erythema Multiforme | Thiram | 5.19 | 16750123 | |
| MESH:D004893 | Erythema Nodosum | Aspartame | 5.46 | 9324739 | |
| MESH:D004931 | Esophageal Achalasia | Diethylnitrosamine | 3.66 | 16302075 | |
| MESH:D004938 | Esophageal Neoplasms | arsenic trioxide | 17.74 | 12903497 | |
| MESH:D004938 | Esophageal Neoplasms | Benzo(a)pyrene | 17.74 | 16530937 | |
| MESH:D004938 | Esophageal Neoplasms | dibutylnitrosamine | 17.74 | 12706858 | |
| MESH:D004938 | Esophageal Neoplasms | Dimethylnitrosamine | 17.74 | 17016578 | |
| MESH:D004938 | Esophageal Neoplasms | Ethanol | 17.74 | 16704527 | |
| MESH:D004938 | Esophageal Neoplasms | Indomethacin | 17.74 | 11005569 | |
| MESH:D004938 | Esophageal Neoplasms | Nitrosamines | 17.74 | 12397637 | |
| MESH:D004938 | Esophageal Neoplasms | nitrosobenzylmethylamine | 17.74 | 16704527 15878914 15623463 15547733 16805852 16510608 15150132 15547721 15264214 | |
| MESH:D004938 | Esophageal Neoplasms | N-methyl-N-benzylnitrosamine | 17.74 | 12222751 | |
| MESH:D004938 | Esophageal Neoplasms | N-methyl-N-nitrosoaniline | 17.74 | 6402317 | |
| MESH:D005124 | Eye Abnormalities | Tetrachlorodibenzodioxin | 4.83 | 11564622 | |
| MESH:D005124 | Eye Abnormalities | Tretinoin | 4.83 | 16938888 9664655 | |
| MESH:D005141 | Eyelid Diseases | Aspartame | 4.92 | 14996049 | |
| MESH:D005218 | Fat Necrosis | Thioacetamide | 4.26 | 16456712 | |
| MESH:D005234 | Fatty Liver | 2,2-dichloro-1,1,1-trifluoroethane | 35.81 | 11548120 | |
| MESH:D005234 | Fatty Liver | arsenic trioxide | 35.81 | 15073043 | |
| MESH:D005234 | Fatty Liver | bicyclol | 35.81 | 16409862 | |
| MESH:D005234 | Fatty Liver | Carbon Tetrachloride | 35.81 | 19224547 12795759 16045604 15959796 17595544 12631006 61145 16239168 | |
| MESH:D005234 | Fatty Liver | Curcumin | 35.81 | 19297423 | |
| MESH:D005234 | Fatty Liver | Cyclosporine | 35.81 | 19224547 | |
| MESH:D005234 | Fatty Liver | Dietary Fats | 35.81 | 18296743 17967931 19551842 19004024 | |
| MESH:D005234 | Fatty Liver | Diethylnitrosamine | 35.81 | 20387270 21071580 | |
| MESH:D005234 | Fatty Liver | Ethanol | 35.81 | 19236843 16409862 18620774 | |
| MESH:D005234 | Fatty Liver | mangiferin | 35.81 | 15975614 | |
| MESH:D005234 | Fatty Liver | Plant Extracts | 35.81 | 15975614 | |
| MESH:D005234 | Fatty Liver | Vinyl Chloride | 35.81 | 12197357 | |
| MESH:D005235 | Fatty Liver, Alcoholic | Ethanol | 4.20 | 17920746 | |
| MESH:D005310 | Fetal Alcohol Syndrome | Ethanol | 3.86 | 16946407 15451040 10194807 15513904 | |
| MESH:D005313 | Fetal Death | Phenytoin | 6.10 | 10627286 | |
| MESH:D005313 | Fetal Death | Tetrachlorodibenzodioxin | 6.10 | 11858732 | |
| MESH:D005317 | Fetal Growth Retardation | 1,2,4-trichlorobenzene | 4.88 | 6884296 | |
| MESH:D005327 | Fetal Resorption | Vitamin A | 3.92 | 16054864 | |
| MESH:D005334 | Fever | Arachidonic Acid | 11.20 | 11852909 | |
| MESH:D005334 | Fever | Aspartame | 11.20 | 9630831 | |
| MESH:D005334 | Fever | Indomethacin | 11.20 | 10431976 17627676 11852909 | |
| MESH:D005334 | Fever | Lipopolysaccharides | 11.20 | 11852909 9205823 | |
| MESH:D005354 | Fibrosarcoma | Indomethacin | 7.36 | 10962813 | |
| MESH:D005354 | Fibrosarcoma | Methylcholanthrene | 7.36 | 10962813 14633661 | |
| MESH:D005355 | Fibrosis | Carbon Tetrachloride | 24.72 | 18705752 | |
| MESH:D005355 | Fibrosis | Curcumin | 24.72 | 18705752 | |
| MESH:D005355 | Fibrosis | Cyclosporine | 24.72 | 12168785 12639820 | |
| MESH:D005355 | Fibrosis | Dietary Fats | 24.72 | 18296743 | |
| MESH:D005355 | Fibrosis | Indomethacin | 24.72 | 17994277 | |
| MESH:D005355 | Fibrosis | Quercetin | 24.72 | 19474275 | |
| MESH:D005355 | Fibrosis | Tetrachlorodibenzodioxin | 24.72 | 20067830 | |
| MESH:D005355 | Fibrosis | Tretinoin | 24.72 | 17994277 | |
| MESH:D005391 | Firesetting Behavior | Testosterone | 4.40 | 7506515 | |
| MESH:D005393 | Fish Diseases | Quinacrine | 4.98 | 12113305 | |
| MESH:D005499 | Folliculitis | Indomethacin | 3.71 | 11298111 | |
| MESH:D005534 | Foot Diseases | Arsenic | 4.10 | 6392382 | |
| MESH:D005706 | Gallbladder Neoplasms | arsenic trioxide | 2.88 | 16904648 | |
| MESH:D005756 | Gastritis | Acetaminophen | 10.76 | 16983495 | |
| MESH:D005756 | Gastritis | Ethanol | 10.76 | 15046732 | |
| MESH:D005756 | Gastritis | Indomethacin | 10.76 | 15046732 | |
| MESH:D005770 | Gastrointestinal Neoplasms | Curcumin | 3.29 | 18462866 | |
| MESH:D030342 | Genetic Diseases, Inborn | vinclozolin | 3.50 | 16973722 | |
| MESH:D005832 | Genital Diseases, Male | vinclozolin | 3.84 | 16417039 | |
| MESH:D005833 | Genital Neoplasms, Female | sodium arsenite | 3.24 | 16452187 | |
| MESH:D005885 | Gingival Hyperplasia | Cyclosporine | 8.16 | 8708960 | |
| MESH:D005885 | Gingival Hyperplasia | Phenytoin | 8.16 | 9029455 | |
| MESH:D019214 | Gingival Overgrowth | Phenytoin | 4.77 | 16390469 14659971 | |
| MESH:D005909 | Glioblastoma | Aspirin | 13.46 | 12870263 | |
| MESH:D005909 | Glioblastoma | Curcumin | 13.46 | 17596214 | |
| MESH:D005909 | Glioblastoma | Indomethacin | 13.46 | 12870263 | |
| MESH:D005909 | Glioblastoma | Quercetin | 13.46 | 19804834 | |
| MESH:D005909 | Glioblastoma | Testosterone | 13.46 | 17162496 | |
| MESH:D005909 | Glioblastoma | Tretinoin | 13.46 | 17312396 | |
| MESH:D005910 | Glioma | 1,3-butadiene | 5.20 | 15814359 | |
| MESH:D005910 | Glioma | Indomethacin | 5.20 | 18371953 16487511 | |
| MESH:D005910 | Glioma | Quercetin | 5.20 | 17643826 | |
| MESH:D005911 | Gliosis | Maneb | 9.61 | 11124998 | |
| MESH:D005911 | Gliosis | Paraquat | 9.61 | 11124998 | |
| MESH:D005923 | Glomerulosclerosis, Focal Segmental | Indomethacin | 3.05 | 11849393 | |
| MESH:D006058 | Gonadal Disorders | Tetrachlorodibenzodioxin | 3.13 | 10696789 | |
| MESH:D006073 | Gout | Indomethacin | 3.91 | 11248219 | |
| MESH:D006261 | Headache | Aspirin | 14.11 | 15240983 | |
| MESH:D006261 | Headache | Ketamine | 14.11 | 11554966 | |
| MESH:D006261 | Headache | Nitric Oxide | 14.11 | 11284996 11554966 | |
| MESH:D006261 | Headache | Nitroglycerin | 14.11 | 11554966 11284996 | |
| MESH:D006258 | Head and Neck Neoplasms | Curcumin | 6.46 | 18829502 18462866 | |
| MESH:D006258 | Head and Neck Neoplasms | Indomethacin | 6.46 | 15482327 | |
| MESH:D006258 | Head and Neck Neoplasms | Tretinoin | 6.46 | 16096774 | |
| MESH:D034381 | Hearing Loss | Dimethyl Sulfoxide | 6.53 | 20641076 | |
| MESH:D034381 | Hearing Loss | Styrene | 6.53 | 17420221 | |
| MESH:D006317 | Hearing Loss, Noise-Induced | Tretinoin | 3.70 | 16084493 | |
| MESH:D006330 | Heart Defects, Congenital | Ascorbic Acid | 10.41 | 16080930 | |
| MESH:D006330 | Heart Defects, Congenital | Benzo(a)pyrene | 10.41 | 20471113 | |
| MESH:D006330 | Heart Defects, Congenital | Tetrachlorodibenzodioxin | 10.41 | 11294989 10048152 | |
| MESH:D006330 | Heart Defects, Congenital | Tretinoin | 10.41 | 14991402 9664655 | |
| MESH:D006330 | Heart Defects, Congenital | Vitamin A | 10.41 | 10992263 16080930 | |
| MESH:D006331 | Heart Diseases | Grape Seed Proanthocyanidins | 8.90 | 12587719 | |
| MESH:D006331 | Heart Diseases | mangiferin | 8.90 | 12093613 | |
| MESH:D006331 | Heart Diseases | Streptozocin | 8.90 | 12093613 | |
| MESH:D006331 | Heart Diseases | Urethane | 8.90 | 16046796 | |
| MESH:D006333 | Heart Failure | Plant Extracts | 2.86 | 18097624 | |
| MESH:D006390 | Hemangioendothelioma | 2-Acetylaminofluorene | 13.23 | 6705139 | |
| MESH:D006390 | Hemangioendothelioma | quinoline | 13.23 | 598648 | |
| MESH:D006390 | Hemangioendothelioma | Vinyl Chloride | 13.23 | 15380572 | |
| MESH:D006393 | Hemangiopericytoma | Vinyl Chloride | 5.40 | 10964802 | |
| MESH:D006394 | Hemangiosarcoma | 1,3-butadiene | 14.57 | 2208121 10930038 | |
| MESH:D006394 | Hemangiosarcoma | 2-Acetylaminofluorene | 14.57 | 6705139 | |
| MESH:D006394 | Hemangiosarcoma | Pentachlorophenol | 14.57 | 15200160 | |
| MESH:D006394 | Hemangiosarcoma | quinoline | 14.57 | 598648 | |
| MESH:D006394 | Hemangiosarcoma | Vinyl Chloride | 14.57 | 12828392 11217710 15989139 12211074 12762079 15999577 12958735 | |
| MESH:D006402 | Hematologic Diseases | Benzene | 3.30 | 16183116 | |
| MESH:D006457 | Hemoglobinuria, Paroxysmal | Cyclosporine | 2.98 | 15720958 | |
| MESH:D006461 | Hemolysis | allyl alcohol | 4.80 | 2222504 | |
| MESH:D006463 | Hemolytic-Uremic Syndrome | Lipopolysaccharides | 3.08 | 16366002 | |
| MESH:D006470 | Hemorrhage | Tetrachlorodibenzodioxin | 2.01 | 11000095 | |
| MESH:D006501 | Hepatic Encephalopathy | Indomethacin | 6.51 | 15633222 | |
| MESH:D006501 | Hepatic Encephalopathy | Thioacetamide | 6.51 | 17276928 15929193 18665440 | |
| MESH:D006505 | Hepatitis | 1-Naphthylisothiocyanate | 19.12 | 18590720 | |
| MESH:D006505 | Hepatitis | allyl alcohol | 19.12 | 11394713 | |
| MESH:D006505 | Hepatitis | Caffeine | 19.12 | 11394713 | |
| MESH:D006505 | Hepatitis | Carbon Tetrachloride | 19.12 | 19110552 19900420 | |
| MESH:D006505 | Hepatitis | Drugs, Chinese Herbal | 19.12 | 18339527 | |
| MESH:D006505 | Hepatitis | Thioacetamide | 19.12 | 16456712 | |
| MESH:D019698 | Hepatitis C, Chronic | Indomethacin | 3.30 | 15135802 | |
| MESH:D006525 | Hepatitis, Viral, Human | allyl sulfide | 4.87 | 15950962 | |
| MESH:D006527 | Hepatolenticular Degeneration | Zinc Sulfate | 3.60 | 17063115 | |
| MESH:D006529 | Hepatomegaly | 2,6-xylidine | 27.71 | 224531 | |
| MESH:D006529 | Hepatomegaly | 2-xylene | 27.71 | 7457013 7457028 | |
| MESH:D006529 | Hepatomegaly | fenarimol | 27.71 | 2387028 | |
| MESH:D006529 | Hepatomegaly | fumonisin B1 | 27.71 | 16221962 | |
| MESH:D006529 | Hepatomegaly | perfluorooctanoic acid | 27.71 | 3609246 | |
| MESH:D006529 | Hepatomegaly | Phenobarbital | 27.71 | 16109766 | |
| MESH:D006529 | Hepatomegaly | propiconazole | 27.71 | 17178688 17178689 | |
| MESH:D006529 | Hepatomegaly | Tetrachlorodibenzodioxin | 27.71 | 16120746 15340226 12621046 | |
| MESH:D006529 | Hepatomegaly | triadimefon | 27.71 | 17178688 17178689 | |
| MESH:D015417 | Hereditary Sensory and Motor Neuropathy | Curcumin | 3.62 | 17701891 | |
| MESH:D006548 | Hernia, Diaphragmatic | Ascorbic Acid | 5.08 | 16863852 16490937 | |
| MESH:D006548 | Hernia, Diaphragmatic | Dexamethasone | 5.08 | 7520565 | |
| MESH:D006548 | Hernia, Diaphragmatic | Vitamin A | 5.08 | 16292552 17436238 16877224 16490937 15707848 16863852 | |
| MESH:D006558 | Herpes Genitalis | Estradiol | 3.57 | 15709030 | |
| MESH:D006561 | Herpes Simplex | Chlorpromazine | 11.98 | 1682908 | |
| MESH:D006561 | Herpes Simplex | mangiferin | 11.98 | 10715843 | |
| MESH:D006561 | Herpes Simplex | Plant Extracts | 11.98 | 10715843 | |
| MESH:D006561 | Herpes Simplex | resveratrol | 11.98 | 16876885 | |
| MESH:D006628 | Hirsutism | Androgens | 8.83 | 17019078 16914592 | |
| MESH:D006628 | Hirsutism | Testosterone | 8.83 | 17019078 | |
| MESH:D015658 | HIV Infections | enfuvirtide | 5.57 | 19539522 | |
| MESH:D015658 | HIV Infections | Plant Extracts | 5.57 | 12878215 | |
| MESH:D015658 | HIV Infections | Vitamin A | 5.57 | 16960176 | |
| MESH:D006679 | HIV Seropositivity | Vitamin A | 4.16 | 17209195 | |
| MESH:D006689 | Hodgkin Disease | sodium arsenite | 2.03 | 12676792 | |
| MESH:D019584 | Hot Flashes | Estradiol | 5.59 | 17088409 | |
| MESH:D019584 | Hot Flashes | Plant Extracts | 5.59 | 17454163 16566672 14716179 | |
| MESH:D006869 | Hydronephrosis | Tetrachlorodibenzodioxin | 2.59 | 16959395 18606429 16354765 15340226 8697196 | |
| MESH:D015160 | Hydrops Fetalis | Mirex | 5.86 | 7265304 | |
| MESH:D012001 | Hyperacusis | Aspirin | 4.30 | 15240983 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 11.65 | 16870215 | |
| MESH:D006930 | Hyperalgesia | Ethanol | 11.65 | 18783367 | |
| MESH:D006930 | Hyperalgesia | Indomethacin | 11.65 | 12727271 | |
| MESH:D006930 | Hyperalgesia | perfluorooctanoic acid | 11.65 | 12083418 | |
| MESH:D006930 | Hyperalgesia | Tretinoin | 11.65 | 16870215 | |
| MESH:D034321 | Hyperamylasemia | Indomethacin | 4.26 | 17883296 | |
| MESH:D017588 | Hyperandrogenism | Androgens | 7.54 | 17019078 | |
| MESH:D017588 | Hyperandrogenism | Testosterone | 7.54 | 17019078 | |
| MESH:D006932 | Hyperbilirubinemia | Carbon Tetrachloride | 3.10 | 16899240 | |
| MESH:D006937 | Hypercholesterolemia | Curcumin | 7.76 | 18704882 | |
| MESH:D006937 | Hypercholesterolemia | Dietary Fats | 7.76 | 21332399 | |
| MESH:D006937 | Hypercholesterolemia | resveratrol | 7.76 | 17188708 | |
| MESH:D006940 | Hyperemia | Indomethacin | 7.98 | 12524144 | |
| MESH:D006940 | Hyperemia | Nitric Oxide | 7.98 | 11156591 | |
| MESH:D017681 | Hypereosinophilic Syndrome | Tretinoin | 3.15 | 16778211 | |
| MESH:D006943 | Hyperglycemia | Quercetin | 2.75 | 18262572 11834736 | |
| MESH:D020138 | Hyperhomocysteinemia | Phenytoin | 5.57 | 10459572 | |
| MESH:D020138 | Hyperhomocysteinemia | Plant Extracts | 5.57 | 16484555 | |
| MESH:D006946 | Hyperinsulinism | mangiferin | 3.74 | 9881663 11315760 | |
| MESH:D017488 | Hyperkeratosis, Epidermolytic | Arsenic | 3.14 | 17050553 | |
| MESH:D006948 | Hyperkinesis | Methamphetamine | 4.09 | 17658665 | |
| MESH:D006949 | Hyperlipidemias | Dietary Fats | 22.89 | 21332399 | |
| MESH:D006949 | Hyperlipidemias | Indomethacin | 22.89 | 17546600 | |
| MESH:D006949 | Hyperlipidemias | mangiferin | 22.89 | 15975614 | |
| MESH:D006949 | Hyperlipidemias | Mirex | 22.89 | 3508472 | |
| MESH:D006949 | Hyperlipidemias | Oleanolic Acid | 22.89 | 8847885 | |
| MESH:D006949 | Hyperlipidemias | Plant Extracts | 22.89 | 15975614 15268973 | |
| MESH:D006949 | Hyperlipidemias | resveratrol | 22.89 | 16873680 | |
| MESH:D017495 | Hyperpigmentation | 1-phenylazo-2-naphthol | 5.80 | 1402006 | |
| MESH:D006965 | Hyperplasia | 1,1-dichloro-1-fluoroethane | 5.44 | 7797176 | |
| MESH:D006967 | Hypersensitivity | mangiferin | 3.44 | 16536907 | |
| MESH:D006973 | Hypertension | Arsenic | 14.49 | 9931084 11953799 16076760 | |
| MESH:D006973 | Hypertension | Aspartame | 14.49 | 18708962 | |
| MESH:D006973 | Hypertension | Benzene | 14.49 | 17940673 | |
| MESH:D006973 | Hypertension | Cyclosporine | 14.49 | 10903974 | |
| MESH:D006973 | Hypertension | Dexamethasone | 14.49 | 17042910 | |
| MESH:D006973 | Hypertension | Quercetin | 14.49 | 18356687 | |
| MESH:D006973 | Hypertension | Sodium, Dietary | 14.49 | 16870316 | |
| MESH:D006973 | Hypertension | Tetrachlorodibenzodioxin | 14.49 | 18670907 18850075 | |
| MESH:D006975 | Hypertension, Portal | Carbon Tetrachloride | 2.69 | 15338365 | |
| MESH:D006976 | Hypertension, Pulmonary | Nitric Oxide | 3.29 | 15838368 | |
| MESH:D017379 | Hypertrophy, Left Ventricular | resveratrol | 3.00 | 17488730 | |
| MESH:D006986 | Hypervitaminosis A | Vitamin A | 4.71 | 16054864 | |
| MESH:D006987 | Hypesthesia | Arsenic | 4.10 | 16093927 | |
| MESH:D007003 | Hypoglycemia | Mirex | 4.79 | 3508472 | |
| MESH:D007006 | Hypogonadism | Testosterone | 3.43 | 12002444 | |
| MESH:D007018 | Hypopituitarism | Testosterone | 4.74 | 17426086 | |
| MESH:D007019 | Hypoproteinemia | Mirex | 5.52 | 6723604 | |
| MESH:D007022 | Hypotension | Zinc Sulfate | 3.17 | 7265320 | |
| MESH:D007077 | Ileal Diseases | Indomethacin | 3.58 | 18306037 10574470 | |
| MESH:D007079 | Ileitis | Indomethacin | 3.91 | 10651667 10647630 16133968 | |
| MESH:D007154 | Immune System Diseases | mangiferin | 4.40 | 16076520 | |
| MESH:D007174 | Impulse Control Disorders | Testosterone | 4.40 | 7506515 | |
| MESH:D007235 | Infant, Premature, Diseases | Indomethacin | 3.91 | 16133044 | |
| MESH:D020244 | Infarction, Middle Cerebral Artery | Progesterone | 6.83 | 15869954 | |
| MESH:D020244 | Infarction, Middle Cerebral Artery | resveratrol | 6.83 | 17600658 | |
| MESH:D007246 | Infertility | Thiram | 4.46 | 6420938 | |
| MESH:D007247 | Infertility, Female | Acrylamide | 3.86 | 11020651 | |
| MESH:D007248 | Infertility, Male | Acrylamide | 17.81 | 15749267 12507653 15355880 11020651 | |
| MESH:D007248 | Infertility, Male | Atrazine | 17.81 | 12948887 | |
| MESH:D007248 | Infertility, Male | Methoxychlor | 17.81 | 11955947 16467254 | |
| MESH:D007248 | Infertility, Male | Paraquat | 17.81 | 4850670 | |
| MESH:D007248 | Infertility, Male | Parathion | 17.81 | 16029889 | |
| MESH:D007248 | Infertility, Male | sodium arsenite | 17.81 | 15346721 12646999 | |
| MESH:D007248 | Infertility, Male | Theophylline | 17.81 | 16988215 | |
| MESH:D007248 | Infertility, Male | vinclozolin | 17.81 | 16467254 | |
| MESH:D007249 | Inflammation | Arachidonic Acid | 35.11 | 9831321 15177302 17371808 | |
| MESH:D007249 | Inflammation | Curcumin | 35.11 | 17151092 18403477 16956363 | |
| MESH:D007249 | Inflammation | Dexamethasone | 35.11 | 8960868 11099482 | |
| MESH:D007249 | Inflammation | Dietary Fats | 35.11 | 20412841 | |
| MESH:D007249 | Inflammation | Diethylnitrosamine | 35.11 | 18785209 | |
| MESH:D007249 | Inflammation | Indomethacin | 35.11 | 12568917 3291741 7812673 | |
| MESH:D007249 | Inflammation | Lipopolysaccharides | 35.11 | 12878042 9205823 17237260 17255318 17963957 | |
| MESH:D007249 | Inflammation | mangiferin | 35.11 | 15222974 | |
| MESH:D007249 | Inflammation | Oleanolic Acid | 35.11 | 8847885 | |
| MESH:D007249 | Inflammation | perfluorooctanoic acid | 35.11 | 12083418 | |
| MESH:D007249 | Inflammation | Plant Extracts | 35.11 | 19332304 12787963 16366677 15997105 | |
| MESH:D007249 | Inflammation | polyphenols | 35.11 | 16366677 | |
| MESH:D007249 | Inflammation | Progesterone | 35.11 | 15869954 | |
| MESH:D007249 | Inflammation | resveratrol | 35.11 | 16366677 | |
| MESH:D007249 | Inflammation | Silymarin | 35.11 | 17213517 | |
| MESH:D007249 | Inflammation | Tetrachlorodibenzodioxin | 35.11 | 12200463 12878042 | |
| MESH:D007249 | Inflammation | Tetradecanoylphorbol Acetate | 35.11 | 11698051 7812673 15177302 8273558 7562506 | |
| MESH:D015212 | Inflammatory Bowel Diseases | Curcumin | 2.42 | 18596194 18200517 | |
| MESH:D007251 | Influenza, Human | Quercetin | 6.42 | 16624496 | |
| MESH:D007251 | Influenza, Human | resveratrol | 6.42 | 16624496 | |
| MESH:D007299 | Insect Bites and Stings | decamethrin | 4.35 | 15189238 | |
| MESH:D007333 | Insulin Resistance | Dietary Fats | 8.67 | 18457598 11836018 | |
| MESH:D007333 | Insulin Resistance | Estradiol | 8.67 | 16393666 16627594 | |
| MESH:D007333 | Insulin Resistance | mangiferin | 8.67 | 11315760 | |
| MESH:D007333 | Insulin Resistance | Propolis | 8.67 | 18057795 | |
| MESH:D007410 | Intestinal Diseases | Indomethacin | 8.58 | 17329856 18236018 15831440 10210152 11713966 15610444 17994277 11686837 11855677 | |
| MESH:D007410 | Intestinal Diseases | Nitric Oxide | 8.58 | 11713966 10210152 11574821 | |
| MESH:D007410 | Intestinal Diseases | Tretinoin | 8.58 | 17994277 | |
| MESH:D007414 | Intestinal Neoplasms | caffeic acid phenethyl ester | 9.02 | 10783313 | |
| MESH:D007414 | Intestinal Neoplasms | Curcumin | 9.02 | 10783313 | |
| MESH:D007414 | Intestinal Neoplasms | Plant Extracts | 9.02 | 12628509 12584176 12351151 | |
| MESH:D002532 | Intracranial Aneurysm | Reactive Oxygen Species | 3.71 | 19381132 | |
| MESH:D019586 | Intracranial Hypertension | Indomethacin | 9.37 | 15241188 | |
| MESH:D019586 | Intracranial Hypertension | Vitamin A | 9.37 | 15955940 | |
| MESH:D019189 | Iron Metabolism Disorders | Lipopolysaccharides | 3.27 | 17255318 | |
| MESH:D007511 | Ischemia | mangiferin | 3.88 | 16806951 | |
| MESH:D007569 | Jaw Abnormalities | Ethanol | 13.84 | 15513904 | |
| MESH:D007569 | Jaw Abnormalities | Tetrachlorodibenzodioxin | 13.84 | 16580747 | |
| MESH:D007569 | Jaw Abnormalities | Tretinoin | 13.84 | 15992940 17551590 | |
| MESH:D007569 | Jaw Abnormalities | triadimefon | 13.84 | 15834900 15992940 | |
| MESH:D007579 | Jejunal Diseases | Indomethacin | 3.58 | 16133968 10574470 18306037 | |
| MESH:D007627 | Keloid | Quercetin | 3.54 | 17086741 | |
| MESH:D007638 | Keratoconjunctivitis Sicca | Cyclosporine | 2.98 | 15604871 | |
| MESH:D007642 | Keratosis | Arsenic | 3.55 | 12749816 16930632 | |
| MESH:D055623 | Keratosis, Actinic | Phenol | 4.98 | 19293009 | |
| MESH:D007674 | Kidney Diseases | 2-dichlorobenzene | 45.21 | 8440869 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 45.21 | 12587719 15629191 | |
| MESH:D007674 | Kidney Diseases | Aspartame | 45.21 | 11409539 | |
| MESH:D007674 | Kidney Diseases | caffeic acid phenethyl ester | 45.21 | 15369732 | |
| MESH:D007674 | Kidney Diseases | Cyclosporine | 45.21 | 10903974 18776723 8314463 | |
| MESH:D007674 | Kidney Diseases | Estradiol | 45.21 | 15618244 | |
| MESH:D007674 | Kidney Diseases | Ethylene Dibromide | 45.21 | 12628311 | |
| MESH:D007674 | Kidney Diseases | ferric nitrilotriacetate | 45.21 | 18617210 15834431 | |
| MESH:D007674 | Kidney Diseases | Grape Seed Proanthocyanidins | 45.21 | 12587719 | |
| MESH:D007674 | Kidney Diseases | Indomethacin | 45.21 | 17190690 | |
| MESH:D007674 | Kidney Diseases | mangiferin | 45.21 | 12093613 | |
| MESH:D007674 | Kidney Diseases | ochratoxin A | 45.21 | 11409539 | |
| MESH:D007674 | Kidney Diseases | Quercetin | 45.21 | 16962696 | |
| MESH:D007674 | Kidney Diseases | sodium arsenite | 45.21 | 20008137 | |
| MESH:D007674 | Kidney Diseases | Streptozocin | 45.21 | 12093613 | |
| MESH:D007674 | Kidney Diseases | tempol | 45.21 | 17640563 | |
| MESH:D007674 | Kidney Diseases | vinylidene chloride | 45.21 | 7839370 | |
| MESH:D007680 | Kidney Neoplasms | 4-dichlorobenzene | 16.39 | 2471290 | |
| MESH:D007680 | Kidney Neoplasms | Cyclosporine | 16.39 | 12371664 | |
| MESH:D007680 | Kidney Neoplasms | Estradiol | 16.39 | 15610895 | |
| MESH:D007680 | Kidney Neoplasms | ferric nitrilotriacetate | 16.39 | 18055543 9667754 | |
| MESH:D007680 | Kidney Neoplasms | ochratoxin A | 16.39 | 16251485 | |
| MESH:D007680 | Kidney Neoplasms | pyridine | 16.39 | 10696769 | |
| MESH:D007680 | Kidney Neoplasms | Vinyl Chloride | 16.39 | 12562636 | |
| MESH:D007683 | Kidney Tubular Necrosis, Acute | Calcium | 3.60 | 16316344 | |
| MESH:D007859 | Learning Disorders | Ethanol | 5.52 | 15451040 | |
| MESH:D007859 | Learning Disorders | mangiferin | 5.52 | 19182383 | |
| MESH:D007889 | Leiomyoma | Curcumin | 3.21 | 18555241 | |
| MESH:D007896 | Leishmaniasis | fenarimol | 5.67 | 18372651 | |
| MESH:D007896 | Leishmaniasis | Nitric Oxide | 5.67 | 17218153 | |
| MESH:D016773 | Leishmaniasis, Cutaneous | Indomethacin | 9.75 | 10320625 12228301 11703811 | |
| MESH:D016773 | Leishmaniasis, Cutaneous | Ketoconazole | 9.75 | 2166429 1311351 8889330 19744259 | |
| MESH:D016773 | Leishmaniasis, Cutaneous | Omeprazole | 9.75 | 19248655 | |
| MESH:D016773 | Leishmaniasis, Cutaneous | Zinc Sulfate | 9.75 | 15237267 | |
| MESH:D007898 | Leishmaniasis, Visceral | Ketoconazole | 3.41 | 11332679 | |
| MESH:D007938 | Leukemia | 1,3-butadiene | 14.86 | 16155477 | |
| MESH:D007938 | Leukemia | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | 14.86 | 12970779 | |
| MESH:D007938 | Leukemia | arsenic trioxide | 14.86 | 15070760 | |
| MESH:D007938 | Leukemia | Benzene | 14.86 | 14694614 17119257 18335105 15935818 | |
| MESH:D007938 | Leukemia | Curcumin | 14.86 | 18462866 | |
| MESH:D007938 | Leukemia | Quercetin | 14.86 | 17468513 | |
| MESH:D007938 | Leukemia | Tretinoin | 14.86 | 17143497 | |
| MESH:D015451 | Leukemia, Lymphocytic, Chronic, B-Cell | Disulfiram | 4.33 | 17026967 | |
| MESH:D015451 | Leukemia, Lymphocytic, Chronic, B-Cell | Drugs, Chinese Herbal | 4.33 | 15802533 | |
| MESH:D015459 | Leukemia-Lymphoma, Adult T-Cell | arsenic trioxide | 8.76 | 12560223 17077332 | |
| MESH:D015459 | Leukemia-Lymphoma, Adult T-Cell | Curcumin | 8.76 | 16106398 | |
| MESH:D015459 | Leukemia-Lymphoma, Adult T-Cell | Docosahexaenoic Acids | 8.76 | 17077332 | |
| MESH:D007948 | Leukemia, Monocytic, Acute | arsenic trioxide | 2.88 | 16972261 | |
| MESH:D015464 | Leukemia, Myelogenous, Chronic, BCR-ABL Positive | arsenic trioxide | 7.31 | 14633726 | |
| MESH:D015464 | Leukemia, Myelogenous, Chronic, BCR-ABL Positive | Indomethacin | 7.31 | 10785260 15631656 16572323 | |
| MESH:D015464 | Leukemia, Myelogenous, Chronic, BCR-ABL Positive | mangiferin | 7.31 | 15498116 | |
| MESH:D007951 | Leukemia, Myeloid | arsenic trioxide | 8.41 | 19077051 | |
| MESH:D007951 | Leukemia, Myeloid | Benzene | 8.41 | 17506065 | |
| MESH:D007951 | Leukemia, Myeloid | Tretinoin | 8.41 | 16482212 16932348 19285840 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | arsenic trioxide | 5.59 | 20471514 16968895 16467208 19850784 17050201 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | Benzene | 5.59 | 19478238 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | Deferoxamine | 5.59 | 20368581 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | Indomethacin | 5.59 | 18360721 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | Tretinoin | 5.59 | 17596541 19850784 16294345 | |
| MESH:D015473 | Leukemia, Promyelocytic, Acute | Arsenic | 12.04 | 17339181 | |
| MESH:D015473 | Leukemia, Promyelocytic, Acute | arsenic trioxide | 12.04 | 17649720 16330433 19225113 12679006 11161223 15622746 16966277 12712474 16823087 17217047 15213294 15336539 9834237 16331271 19642359 15748426 19075265 17869043 19035177 12018890 16112521 17712046 11468182 16891316 17107899 | |
| MESH:D015473 | Leukemia, Promyelocytic, Acute | caffeic acid phenethyl ester | 12.04 | 16766008 | |
| MESH:D015473 | Leukemia, Promyelocytic, Acute | resveratrol | 12.04 | 16087638 | |
| MESH:D015473 | Leukemia, Promyelocytic, Acute | Tretinoin | 12.04 | 16331271 12679006 19225113 17649720 19029980 16788101 15748426 17506722 17217047 17294898 17107899 16823087 19642359 16891316 16935935 17361223 16766008 17339181 19035177 19075265 17301526 9834237 16140955 17712046 17368321 | |
| MESH:D015458 | Leukemia, T-Cell | arsenic trioxide | 7.12 | 16882451 | |
| MESH:D015458 | Leukemia, T-Cell | Curcumin | 7.12 | 16106398 | |
| MESH:D007964 | Leukocytosis | Indomethacin | 3.91 | 16537180 | |
| MESH:D007969 | Leukomalacia, Periventricular | Indomethacin | 4.26 | 17980183 | |
| MESH:D007970 | Leukopenia | Lipopolysaccharides | 3.27 | 15821434 | |
| MESH:D007984 | Leydig Cell Tumor | perfluorooctanoic acid | 8.19 | 8812269 | |
| MESH:D007984 | Leydig Cell Tumor | vinclozolin | 8.19 | 16417039 | |
| MESH:D017880 | Limb Deformities, Congenital | Disulfiram | 9.98 | 17676605 | |
| MESH:D017880 | Limb Deformities, Congenital | Ethanol | 9.98 | 17676605 | |
| MESH:D017880 | Limb Deformities, Congenital | Tretinoin | 9.98 | 9224671 | |
| MESH:D017880 | Limb Deformities, Congenital | Vitamin A | 9.98 | 16054864 | |
| MESH:D008064 | Lipidoses | Chlorpromazine | 6.97 | 17567588 15342952 | |
| MESH:D008064 | Lipidoses | Ketoconazole | 6.97 | 17567588 | |
| MESH:D008064 | Lipidoses | Thioridazine | 6.97 | 17567588 15342952 | |
| MESH:D008101 | Liver Abscess, Amebic | Indomethacin | 4.26 | 11479899 | |
| MESH:D008103 | Liver Cirrhosis | Carbon Tetrachloride | 29.03 | 11408273 16943688 16239168 17174718 16221502 17334410 17157831 21278145 11903743 | |
| MESH:D008103 | Liver Cirrhosis | Dietary Fats | 29.03 | 18296743 | |
| MESH:D008103 | Liver Cirrhosis | Diethylnitrosamine | 29.03 | 20032147 18522880 18665156 19638242 18407596 | |
| MESH:D008103 | Liver Cirrhosis | Drugs, Chinese Herbal | 29.03 | 17163593 | |
| MESH:D008103 | Liver Cirrhosis | Ethanol | 29.03 | 15289165 | |
| MESH:D008103 | Liver Cirrhosis | Phenobarbital | 29.03 | 21047994 | |
| MESH:D008103 | Liver Cirrhosis | Plant Extracts | 29.03 | 17157831 | |
| MESH:D008103 | Liver Cirrhosis | puerarin | 29.03 | 16426832 | |
| MESH:D008103 | Liver Cirrhosis | Silymarin | 29.03 | 17213517 | |
| MESH:D008103 | Liver Cirrhosis | Vinyl Chloride | 29.03 | 15354062 11679801 15289165 12958735 12499459 | |
| MESH:D008103 | Liver Cirrhosis | Vitamin A | 29.03 | 16256175 | |
| MESH:D008104 | Liver Cirrhosis, Alcoholic | Ethanol | 8.98 | 18295389 | |
| MESH:D008104 | Liver Cirrhosis, Alcoholic | Propolis | 8.98 | 18295389 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | 1,3-dimethylthiourea | 43.28 | 11682029 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | allyl alcohol | 43.28 | 11063159 18564211 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | bicyclol | 43.28 | 15730626 16603200 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Carbon Tetrachloride | 43.28 | 12958196 17805973 17565644 12632514 18429990 18210741 18187930 15673190 18156304 17698563 16116963 18395914 15959796 16015684 14716833 15931870 18263696 15925388 16011737 14748882 18418968 15893842 17976157 15338365 13678700 20821823 18395095 14724832 12609069 16638106 17525996 12649538 18420326 14716496 12667390 12389079 15057751 17823541 18705752 12666154 12445421 16136751 17640975 18472094 15876570 15650968 18317297 18472332 17900296 15370692 17944888 16248980 17766677 11481614 16097048 18277467 16033810 17869086 17631135 12445418 18481824 18166357 16192424 17557913 12632512 12898905 15052691 15730626 12586293 14512876 18376398 14620537 15996030 12546737 16027843 17922224 15818738 17481882 15123356 18006644 17721639 18412020 18205269 18054572 17761835 12741479 18279442 17708605 18251166 10355542 17714472 15362042 18339082 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Carnitine | 43.28 | 14748882 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Curcumin | 43.28 | 17355460 18006644 18705752 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Dexamethasone | 43.28 | 16718785 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Dimethylnitrosamine | 43.28 | 17724770 16570917 14709902 17881167 14643895 15942678 17465448 17719030 15571005 15138612 15479170 15298665 15577212 15492853 17348192 15733078 18672772 16270385 18239293 18210741 15864749 15842777 16009107 14659978 15369754 12925901 18567088 17666798 15591649 17036385 17201889 15081153 17198567 18371158 15383259 18237412 18637143 18364076 16603200 15099470 17203207 17196135 15798949 15763062 14568256 15793283 15161499 16042886 16627068 15067225 17534399 15504291 16169303 18629640 14726149 17640959 12918455 17432682 15339415 15744066 15366600 18095165 15723089 16544323 15086199 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Dimethyl Sulfoxide | 43.28 | 11682029 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Drugs, Chinese Herbal | 43.28 | 15641146 15383259 15818738 16610055 17036385 12632512 17666798 18567088 17629604 15864749 15339415 15754396 15849816 17348192 15763062 17881167 18371158 15744066 18237412 18606216 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | epigallocatechin gallate | 43.28 | 17481882 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Estradiol | 43.28 | 14716833 14659978 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Ethanol | 43.28 | 18166357 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | gadolinium chloride | 43.28 | 12666154 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Indomethacin | 43.28 | 18194892 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Lipopolysaccharides | 43.28 | 12878042 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Oleanolic Acid | 43.28 | 10355542 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Plant Extracts | 43.28 | 15479170 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Propolis | 43.28 | 18295389 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Quercetin | 43.28 | 12741479 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | S-Adenosylmethionine | 43.28 | 15983038 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Silymarin | 43.28 | 18277467 15864749 15754394 17198567 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Tetrachlorodibenzodioxin | 43.28 | 12878042 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Thioacetamide | 43.28 | 12175628 18295389 15362042 15075984 16489207 15334695 16343077 17629604 17292413 15158331 15288472 15316131 15465738 16098781 17355460 16248980 18615449 18380797 12557150 11172339 18263696 15288473 16511523 15078482 18606216 16126171 17127702 15474484 14739098 15716488 18395095 18031379 16097051 18458672 12891558 11682029 10677585 15095483 17050028 11481614 12085344 12679928 18416461 12531686 18032466 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Tretinoin | 43.28 | 18397230 16248980 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | trichloromethyl free radical | 43.28 | 20821823 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Vitamin A | 43.28 | 16248980 | |
| MESH:D008107 | Liver Diseases | 1,1,1,2-tetrafluoro-2-chloroethane | 82.90 | 9284778 | |
| MESH:D008107 | Liver Diseases | 1,2,4,5-tetrachlorobenzene | 82.90 | 1949037 | |
| MESH:D008107 | Liver Diseases | 1,2,4-trichlorobenzene | 82.90 | 1949037 | |
| MESH:D008107 | Liver Diseases | 1-Naphthylisothiocyanate | 82.90 | 17184895 | |
| MESH:D008107 | Liver Diseases | 2,2-dichloro-1,1,1-trifluoroethane | 82.90 | 9284778 | |
| MESH:D008107 | Liver Diseases | 2-dichlorobenzene | 82.90 | 1853346 8440869 1949037 8661352 | |
| MESH:D008107 | Liver Diseases | 4-dichlorobenzene | 82.90 | 1949037 7801330 8661352 1715830 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 82.90 | 19014921 16610002 12969438 12587719 19460945 11587558 19784758 16611625 | |
| MESH:D008107 | Liver Diseases | Arsenic | 82.90 | 11134558 | |
| MESH:D008107 | Liver Diseases | Carbon Tetrachloride | 82.90 | 16246199 17285989 15720792 16964402 15830285 | |
| MESH:D008107 | Liver Diseases | chlorobenzene | 82.90 | 1949037 | |
| MESH:D008107 | Liver Diseases | Chlorpromazine | 82.90 | 14986274 | |
| MESH:D008107 | Liver Diseases | Curcumin | 82.90 | 16956363 | |
| MESH:D008107 | Liver Diseases | Diethylnitrosamine | 82.90 | 17034775 | |
| MESH:D008107 | Liver Diseases | Docosahexaenoic Acids | 82.90 | 17056761 | |
| MESH:D008107 | Liver Diseases | Drugs, Chinese Herbal | 82.90 | 17207593 | |
| MESH:D008107 | Liver Diseases | Gasoline | 82.90 | 1715830 | |
| MESH:D008107 | Liver Diseases | Grape Seed Proanthocyanidins | 82.90 | 12587719 | |
| MESH:D008107 | Liver Diseases | Lindane | 82.90 | 1715830 | |
| MESH:D008107 | Liver Diseases | Oleanolic Acid | 82.90 | 8847885 15720792 | |
| MESH:D008107 | Liver Diseases | pentachlorobenzene | 82.90 | 1949037 | |
| MESH:D008107 | Liver Diseases | Phenobarbital | 82.90 | 19363144 | |
| MESH:D008107 | Liver Diseases | Phenytoin | 82.90 | 14986274 | |
| MESH:D008107 | Liver Diseases | Plant Extracts | 82.90 | 17034775 | |
| MESH:D008107 | Liver Diseases | polyphenols | 82.90 | 16698588 | |
| MESH:D008107 | Liver Diseases | propiconazole | 82.90 | 19363144 | |
| MESH:D008107 | Liver Diseases | Silymarin | 82.90 | 17213517 | |
| MESH:D008107 | Liver Diseases | Tetrachloroethylene | 82.90 | 17267091 | |
| MESH:D008107 | Liver Diseases | Thioacetamide | 82.90 | 18374380 16337175 15158337 | |
| MESH:D008107 | Liver Diseases | triadimefon | 82.90 | 19363144 | |
| MESH:D008107 | Liver Diseases | Vinyl Chloride | 82.90 | 15211785 16270392 | |
| MESH:D008107 | Liver Diseases | Vitamin A | 82.90 | 16175620 | |
| MESH:D008108 | Liver Diseases, Alcoholic | Chlormethiazole | 15.84 | 16054987 | |
| MESH:D008108 | Liver Diseases, Alcoholic | Ethanol | 15.84 | 17207112 17347304 | |
| MESH:D008108 | Liver Diseases, Alcoholic | Silymarin | 15.84 | 17213517 | |
| MESH:D008108 | Liver Diseases, Alcoholic | Vitamin A | 15.84 | 16762690 | |
| MESH:D017093 | Liver Failure | Carbon Tetrachloride | 2.76 | 15123358 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 12.64 | 17185352 16871587 | |
| MESH:D017114 | Liver Failure, Acute | Carbon Tetrachloride | 12.64 | 14706259 16899240 | |
| MESH:D017114 | Liver Failure, Acute | Dimethylnitrosamine | 12.64 | 17457977 | |
| MESH:D017114 | Liver Failure, Acute | Thioacetamide | 12.64 | 12479984 17276928 15313186 15633222 | |
| MESH:D008113 | Liver Neoplasms | marker/mechanism | 17093202 | ||
| MESH:D008113 | Liver Neoplasms | 1,2,4,5-tetrachlorobenzene | 85.09 | 9714333 | |
| MESH:D008113 | Liver Neoplasms | 1,3-butadiene | 85.09 | 2208121 | |
| MESH:D008113 | Liver Neoplasms | 2-Acetylaminofluorene | 85.09 | 10672840 18001218 10737359 16273603 11376686 14678523 | |
| MESH:D008113 | Liver Neoplasms | 4-dichlorobenzene | 85.09 | 12748734 17688981 | |
| MESH:D008113 | Liver Neoplasms | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 85.09 | 15890375 | |
| MESH:D008113 | Liver Neoplasms | 9-(4'-aminophenyl)-9H-pyrido(3,4-b)indole | 85.09 | 12970073 | |
| MESH:D008113 | Liver Neoplasms | Aflatoxin B1 | 85.09 | 2125692 15890375 9163691 18177683 | |
| MESH:D008113 | Liver Neoplasms | Arsenic | 85.09 | 16368122 | |
| MESH:D008113 | Liver Neoplasms | arsenic trioxide | 85.09 | 14682389 | |
| MESH:D008113 | Liver Neoplasms | Benzo(a)pyrene | 85.09 | 21137059 20195826 | |
| MESH:D008113 | Liver Neoplasms | beta-Naphthoflavone | 85.09 | 21295105 19389873 | |
| MESH:D008113 | Liver Neoplasms | Carbon Tetrachloride | 85.09 | 19294768 | |
| MESH:D008113 | Liver Neoplasms | Carnitine | 85.09 | 19294768 | |
| MESH:D008113 | Liver Neoplasms | ciprofibrate | 85.09 | 12771043 | |
| MESH:D008113 | Liver Neoplasms | dibutylnitrosamine | 85.09 | 15881669 | |
| MESH:D008113 | Liver Neoplasms | Diethylnitrosamine | 85.09 | 2862719 15175105 19090486 15885732 19073162 19294768 20501860 18648771 20405173 19255062 20434301 19254457 20492335 21167192 19850985 20583210 10737359 20101389 20118626 19996281 21071580 20137499 18978307 12771043 19551842 21278145 21047994 20452335 16942905 19690152 19642983 18644402 19427195 19812893 2422723 9163691 19833225 19638242 19499222 18977376 19256749 12112319 19426721 18754104 | |
| MESH:D008113 | Liver Neoplasms | diethylthiourea | 85.09 | 11940454 | |
| MESH:D008113 | Liver Neoplasms | Dimethylnitrosamine | 85.09 | 15890375 3113478 | |
| MESH:D008113 | Liver Neoplasms | Drugs, Chinese Herbal | 85.09 | 18339527 | |
| MESH:D008113 | Liver Neoplasms | Pentachlorophenol | 85.09 | 10696769 | |
| MESH:D008113 | Liver Neoplasms | perfluorooctanoic acid | 85.09 | 18709148 14757943 | |
| MESH:D008113 | Liver Neoplasms | Phenobarbital | 85.09 | 19073162 19482888 15975961 8742319 19812893 21047994 | |
| MESH:D008113 | Liver Neoplasms | Plant Extracts | 85.09 | 19168119 | |
| MESH:D008113 | Liver Neoplasms | propiconazole | 85.09 | 19028983 | |
| MESH:D008113 | Liver Neoplasms | Quercetin | 85.09 | 18980244 | |
| MESH:D008113 | Liver Neoplasms | resveratrol | 85.09 | 19812893 20405173 19073162 19321006 | |
| MESH:D008113 | Liver Neoplasms | Silymarin | 85.09 | 19168119 | |
| MESH:D008113 | Liver Neoplasms | sodium arsenite | 85.09 | 16712894 15276417 | |
| MESH:D008113 | Liver Neoplasms | Tetrachlorodibenzodioxin | 85.09 | 16984957 | |
| MESH:D008113 | Liver Neoplasms | triadimefon | 85.09 | 19028983 | |
| MESH:D008113 | Liver Neoplasms | Urethane | 85.09 | 16391232 17559639 17093202 | |
| MESH:D008113 | Liver Neoplasms | Vinyl Chloride | 85.09 | 12211074 12762079 15999577 11024202 10629081 11679801 10964802 | |
| MESH:D008114 | Liver Neoplasms, Experimental | marker/mechanism | 18056438 | ||
| MESH:D008114 | Liver Neoplasms, Experimental | 1-phenylazo-2-naphthol | 64.29 | 2563599 | |
| MESH:D008114 | Liver Neoplasms, Experimental | 2,2-dichloro-1,1,1-trifluoroethane | 64.29 | 7601319 | |
| MESH:D008114 | Liver Neoplasms, Experimental | 2-Acetylaminofluorene | 64.29 | 6150874 534488 1399818 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Aflatoxin B1 | 64.29 | 8603461 | |
| MESH:D008114 | Liver Neoplasms, Experimental | arsenic trioxide | 64.29 | 20377131 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Ascorbic Acid | 64.29 | 18544905 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Benzene | 64.29 | 12562636 | |
| MESH:D008114 | Liver Neoplasms, Experimental | beta-Naphthoflavone | 64.29 | 18164116 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Carbon Tetrachloride | 64.29 | 15583823 12014681 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Diethylnitrosamine | 64.29 | 17854601 18079962 2563599 19009564 17174075 18544905 19519916 3124819 9362446 18093689 19126423 18775883 19004024 19539802 18164116 16267830 18253720 16842330 17942915 18308698 21159647 18282651 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Dimethylnitrosamine | 64.29 | 6150874 15603536 1848544 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Hexachlorobenzene | 64.29 | 1423854 | |
| MESH:D008114 | Liver Neoplasms, Experimental | kojic acid | 64.29 | 18544905 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Methylcholanthrene | 64.29 | 1399818 598648 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Phenobarbital | 64.29 | 18308698 1399818 6150874 17172636 2563599 | |
| MESH:D008114 | Liver Neoplasms, Experimental | propiconazole | 64.29 | 17178689 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Quercetin | 64.29 | 19519916 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Tetrachlorodibenzodioxin | 64.29 | 12151625 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Tetrachloroethylene | 64.29 | 7955063 | |
| MESH:D008114 | Liver Neoplasms, Experimental | triadimefon | 64.29 | 17178689 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Trichloroethylene | 64.29 | 7955063 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Vinyl Chloride | 64.29 | 12562636 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Vitamin A | 64.29 | 17113696 | |
| MESH:D008133 | Long QT Syndrome | arsenic trioxide | 4.77 | 15213294 | |
| MESH:D008133 | Long QT Syndrome | Thioridazine | 4.77 | 20210726 | |
| MESH:D008171 | Lung Diseases | Ascorbic Acid | 11.22 | 16863852 | |
| MESH:D008171 | Lung Diseases | Grape Seed Proanthocyanidins | 11.22 | 12587719 | |
| MESH:D008171 | Lung Diseases | Ozone | 11.22 | 19066396 8266340 | |
| MESH:D008171 | Lung Diseases | sodium arsenite | 11.22 | 19095001 | |
| MESH:D008171 | Lung Diseases | Vitamin A | 11.22 | 16863852 | |
| MESH:D017563 | Lung Diseases, Interstitial | Benzene | 3.37 | 14698565 | |
| MESH:D055370 | Lung Injury | Lipopolysaccharides | 10.47 | 21114838 | |
| MESH:D055370 | Lung Injury | Nitric Oxide | 10.47 | 11395602 | |
| MESH:D055370 | Lung Injury | Ozone | 10.47 | 20417186 | |
| MESH:D055370 | Lung Injury | vinylidene chloride | 10.47 | 3697828 | |
| MESH:D008175 | Lung Neoplasms | marker/mechanism | 1673675 17093202 | ||
| MESH:D008175 | Lung Neoplasms | 1,3-butadiene | 58.32 | 2208121 16860786 17372256 | |
| MESH:D008175 | Lung Neoplasms | 2-Acetylaminofluorene | 58.32 | 11376686 | |
| MESH:D008175 | Lung Neoplasms | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 58.32 | 15893417 17139156 19931552 14755239 18508827 15172992 16401635 9255578 12438228 18813816 16061637 | |
| MESH:D008175 | Lung Neoplasms | Acetaldehyde | 58.32 | 17372256 | |
| MESH:D008175 | Lung Neoplasms | Acrylonitrile | 58.32 | 17372256 | |
| MESH:D008175 | Lung Neoplasms | Aflatoxin B1 | 58.32 | 14755239 | |
| MESH:D008175 | Lung Neoplasms | Arsenic | 58.32 | 17306315 17976673 19168569 | |
| MESH:D008175 | Lung Neoplasms | arsenic trioxide | 58.32 | 11798837 19825857 | |
| MESH:D008175 | Lung Neoplasms | Ascorbic Acid | 58.32 | 16401635 | |
| MESH:D008175 | Lung Neoplasms | Azoxymethane | 58.32 | 15824018 | |
| MESH:D008175 | Lung Neoplasms | Benzene | 58.32 | 12562636 | |
| MESH:D008175 | Lung Neoplasms | Benzo(a)pyrene | 58.32 | 20464547 18569708 17053015 18816296 20064080 20869020 18520028 20135361 6695378 | |
| MESH:D008175 | Lung Neoplasms | Curcumin | 58.32 | 16243823 19359593 18462866 | |
| MESH:D008175 | Lung Neoplasms | Dexamethasone | 58.32 | 11195469 15824018 | |
| MESH:D008175 | Lung Neoplasms | Diethylnitrosamine | 58.32 | 21163286 20970405 6695378 20512841 | |
| MESH:D008175 | Lung Neoplasms | Dimethylnitrosamine | 58.32 | 11884234 19555203 16061637 | |
| MESH:D008175 | Lung Neoplasms | Drugs, Chinese Herbal | 58.32 | 18339527 | |
| MESH:D008175 | Lung Neoplasms | Indomethacin | 58.32 | 11053908 16537180 11497255 | |
| MESH:D008175 | Lung Neoplasms | mangiferin | 58.32 | 18816296 18520028 18569708 | |
| MESH:D008175 | Lung Neoplasms | Methoxsalen | 58.32 | 15893417 | |
| MESH:D008175 | Lung Neoplasms | Methylcholanthrene | 58.32 | 1399818 20512841 16271038 21163286 15390079 20970405 7750092 10545420 16337739 17909032 9230183 6695378 11893704 | |
| MESH:D008175 | Lung Neoplasms | Methylene Chloride | 58.32 | 15172992 | |
| MESH:D008175 | Lung Neoplasms | Ozone | 58.32 | 7614698 8597069 | |
| MESH:D008175 | Lung Neoplasms | Plant Extracts | 58.32 | 20869020 | |
| MESH:D008175 | Lung Neoplasms | Quercetin | 58.32 | 16280456 | |
| MESH:D008175 | Lung Neoplasms | Smoke | 58.32 | 11091918 | |
| MESH:D008175 | Lung Neoplasms | sodium arsenite | 58.32 | 19931552 17306315 17077188 15276417 16712894 | |
| MESH:D008175 | Lung Neoplasms | Styrene | 58.32 | 12562636 | |
| MESH:D008175 | Lung Neoplasms | Tetrachlorodibenzodioxin | 58.32 | 19555203 11884234 | |
| MESH:D008175 | Lung Neoplasms | Tetradecanoylphorbol Acetate | 58.32 | 11807781 | |
| MESH:D008175 | Lung Neoplasms | Urethane | 58.32 | 14587096 15166089 11062179 12466968 16337739 17255336 11074608 12117781 11497255 10530776 16391232 17195641 11552296 17093202 11307925 15902970 6695378 10997738 11246140 16926031 12957351 16007126 10822126 15136453 11893704 11807781 7750092 16204055 16289808 12765245 10779650 16788158 11544531 11323394 11992545 | |
| MESH:D008175 | Lung Neoplasms | vinyl carbamate | 58.32 | 14755239 15824018 11195469 16247444 17163412 17361011 17363558 15172992 12117777 12438228 12765245 11134547 16885199 | |
| MESH:D008175 | Lung Neoplasms | Vinyl Chloride | 58.32 | 12958735 12562636 | |
| MESH:D008178 | Lupus Erythematosus, Cutaneous | Rifampin | 4.69 | 11422169 | |
| MESH:D008180 | Lupus Erythematosus, Systemic | Rifampin | 3.39 | 11422169 | |
| MESH:D008223 | Lymphoma | 1,3-butadiene | 11.27 | 17941976 2208121 18798262 8764131 11980663 9205081 9488045 | |
| MESH:D008223 | Lymphoma | Benzene | 11.27 | 17119257 17584886 | |
| MESH:D008223 | Lymphoma | Curcumin | 11.27 | 18462866 | |
| MESH:D008223 | Lymphoma | Nitric Oxide | 11.27 | 16166326 | |
| MESH:D008223 | Lymphoma | Pentachlorophenol | 11.27 | 12669308 | |
| MESH:D016393 | Lymphoma, B-Cell | resveratrol | 2.96 | 17088997 | |
| MESH:D008228 | Lymphoma, Non-Hodgkin | Carnitine | 5.39 | 16283381 | |
| MESH:D008228 | Lymphoma, Non-Hodgkin | resveratrol | 5.39 | 14749477 | |
| MESH:D016399 | Lymphoma, T-Cell | Curcumin | 3.29 | 16173963 | |
| MESH:D016778 | Malaria, Falciparum | Thioridazine | 4.39 | 16882315 | |
| MESH:D015674 | Mammary Neoplasms, Animal | 1,3-butadiene | 20.95 | 2208121 | |
| MESH:D015674 | Mammary Neoplasms, Animal | Acrylonitrile | 20.95 | 12562636 | |
| MESH:D015674 | Mammary Neoplasms, Animal | Benzene | 20.95 | 12562636 | |
| MESH:D015674 | Mammary Neoplasms, Animal | resveratrol | 20.95 | 15688416 | |
| MESH:D015674 | Mammary Neoplasms, Animal | Styrene | 20.95 | 12562636 | |
| MESH:D015674 | Mammary Neoplasms, Animal | Vinyl Chloride | 20.95 | 12562636 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | 1,3-butadiene | 17.15 | 11921183 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Benzene | 17.15 | 11921183 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Drugs, Chinese Herbal | 17.15 | 14758024 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Estradiol | 17.15 | 11408345 11807958 17203775 16891317 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Ethylene Dibromide | 17.15 | 11921183 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | ochratoxin A | 17.15 | 11921183 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Progesterone | 17.15 | 17203775 11408345 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | resveratrol | 17.15 | 11606380 8985016 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Tetradecanoylphorbol Acetate | 17.15 | 8985016 | |
| MESH:D020149 | Manganese Poisoning | Estradiol | 3.03 | 19453300 | |
| MESH:D008527 | Medulloblastoma | Tretinoin | 1.98 | 17453147 | |
| MESH:D008545 | Melanoma | 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid | 8.48 | 17992120 | |
| MESH:D008545 | Melanoma | Curcumin | 8.48 | 17885582 18462866 | |
| MESH:D008545 | Melanoma | Disulfiram | 8.48 | 15367699 | |
| MESH:D008545 | Melanoma | epigallocatechin gallate | 8.48 | 17992120 11746506 | |
| MESH:D008545 | Melanoma | Reactive Oxygen Species | 8.48 | 17992120 | |
| MESH:D008545 | Melanoma | resveratrol | 8.48 | 17992120 | |
| MESH:D008545 | Melanoma | sodium arsenite | 8.48 | 19082730 16487513 | |
| MESH:D008545 | Melanoma | Tretinoin | 8.48 | 16752155 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 2.17 | 19513568 | |
| MESH:D008569 | Memory Disorders | Curcumin | 8.28 | 17263510 | |
| MESH:D008569 | Memory Disorders | Ethanol | 8.28 | 18411066 15451040 | |
| MESH:D008569 | Memory Disorders | mangiferin | 8.28 | 19182383 | |
| MESH:D008591 | Meningomyelocele | Tretinoin | 3.01 | 16940565 | |
| MESH:D001523 | Mental Disorders | Chlorpromazine | 7.79 | 16856516 | |
| MESH:D001523 | Mental Disorders | Desipramine | 7.79 | 16856516 | |
| MESH:D001523 | Mental Disorders | Fluphenazine | 7.79 | 16856516 | |
| MESH:D001523 | Mental Disorders | Thioridazine | 7.79 | 16856516 | |
| MESH:D008607 | Mental Retardation | Phenytoin | 3.90 | 9212184 | |
| MESH:D008607 | Mental Retardation | Toluene | 3.90 | 9294310 | |
| MESH:D008654 | Mesothelioma | Atrazine | 2.75 | 1916698 | |
| MESH:D008659 | Metabolic Diseases | resveratrol | 3.05 | 17112576 | |
| MESH:D008664 | Metal Metabolism, Inborn Errors | Cyclosporine | 3.33 | 16801185 | |
| MESH:D008679 | Metaplasia | Ozone | 3.65 | 10496685 | |
| MESH:D008708 | Methemoglobinemia | Nitroglycerin | 5.49 | 3537620 | |
| MESH:D008708 | Methemoglobinemia | Phenacetin | 5.49 | 1949026 16296465 4834387 3537620 | |
| MESH:D008850 | Microphthalmos | ochratoxin A | 4.40 | 20036863 | |
| MESH:D008881 | Migraine Disorders | Aspartame | 8.54 | 10792367 18627677 | |
| MESH:D008881 | Migraine Disorders | Aspirin | 8.54 | 15240983 | |
| MESH:D008881 | Migraine Disorders | Indomethacin | 8.54 | 11903285 | |
| MESH:D008881 | Migraine Disorders | Nitric Oxide | 8.54 | 11701602 | |
| MESH:D020326 | Migraine without Aura | Nitric Oxide | 6.59 | 14659530 11304026 | |
| MESH:D020326 | Migraine without Aura | Nitroglycerin | 6.59 | 14659530 | |
| MESH:D019957 | Motor Skills Disorders | Toluene | 3.87 | 9294310 | |
| MESH:D009062 | Mouth Neoplasms | Benzo(a)pyrene | 4.63 | 16381670 | |
| MESH:D009062 | Mouth Neoplasms | Indomethacin | 4.63 | 12636206 | |
| MESH:D009101 | Multiple Myeloma | arsenic trioxide | 13.37 | 14977855 19549372 19417148 15949261 11468182 | |
| MESH:D009101 | Multiple Myeloma | Benzene | 13.37 | 17119195 | |
| MESH:D009101 | Multiple Myeloma | Curcumin | 13.37 | 19372569 | |
| MESH:D009101 | Multiple Myeloma | Dexamethasone | 13.37 | 16118317 15867202 15744524 | |
| MESH:D009101 | Multiple Myeloma | resveratrol | 13.37 | 14749477 17935668 17164350 17049120 16267019 16490592 | |
| MESH:D009101 | Multiple Myeloma | Vitamin A | 13.37 | 16374440 | |
| MESH:D009134 | Muscular Atrophy, Spinal | Curcumin | 12.94 | 17962980 | |
| MESH:D009134 | Muscular Atrophy, Spinal | epigallocatechin gallate | 12.94 | 17962980 | |
| MESH:D009134 | Muscular Atrophy, Spinal | resveratrol | 12.94 | 17962980 | |
| MESH:D009145 | Mushroom Poisoning | Silymarin | 5.48 | 17213517 | |
| MESH:D009164 | Mycobacterium Infections | Isoniazid | 7.03 | 18474467 | |
| MESH:D009164 | Mycobacterium Infections | Rifampin | 7.03 | 18474467 | |
| MESH:D009175 | Mycoplasma Infections | Chlorpromazine | 4.55 | 10773494 | |
| MESH:D009182 | Mycosis Fungoides | arsenic trioxide | 8.68 | 18349030 | |
| MESH:D009182 | Mycosis Fungoides | Methoxsalen | 8.68 | 16259964 | |
| MESH:D009190 | Myelodysplastic Syndromes | arsenic trioxide | 6.26 | 16882451 16105982 | |
| MESH:D009190 | Myelodysplastic Syndromes | Dexamethasone | 6.26 | 9809623 | |
| MESH:D009190 | Myelodysplastic Syndromes | Tretinoin | 6.26 | 17596541 | |
| MESH:D009203 | Myocardial Infarction | Aspirin | 8.50 | 12692751 | |
| MESH:D009203 | Myocardial Infarction | mangiferin | 8.50 | 17052832 16584858 16697266 16538859 19172585 | |
| MESH:D009203 | Myocardial Infarction | Nitroglycerin | 8.50 | 14729435 | |
| MESH:D009203 | Myocardial Infarction | Quercetin | 8.50 | 19595682 | |
| MESH:D009203 | Myocardial Infarction | resveratrol | 8.50 | 17015251 17188708 16317513 16525036 17125593 16456233 | |
| MESH:D017202 | Myocardial Ischemia | Arsenic | 8.13 | 15371236 | |
| MESH:D017202 | Myocardial Ischemia | resveratrol | 8.13 | 17015251 17125593 | |
| MESH:D017202 | Myocardial Ischemia | Tetrachlorodibenzodioxin | 8.13 | 12213967 | |
| MESH:D015428 | Myocardial Reperfusion Injury | Estradiol | 4.54 | 16810080 | |
| MESH:D015428 | Myocardial Reperfusion Injury | Quercetin | 4.54 | 19207477 | |
| MESH:D009205 | Myocarditis | resveratrol | 3.33 | 17322642 | |
| MESH:D020191 | Myoclonic Epilepsies, Progressive | Phenobarbital | 7.75 | 17484760 | |
| MESH:D020191 | Myoclonic Epilepsies, Progressive | Phenytoin | 7.75 | 17484760 | |
| MESH:D009224 | Myotonia Congenita | Phenytoin | 3.98 | 1896199 | |
| MESH:D009325 | Nausea | Aspirin | 3.77 | 15240983 | |
| MESH:D009361 | Neoplasm Invasiveness | arsenic trioxide | 9.51 | 16624393 | |
| MESH:D009361 | Neoplasm Invasiveness | Curcumin | 9.51 | 18495463 | |
| MESH:D009361 | Neoplasm Invasiveness | Disulfiram | 9.51 | 18047805 | |
| MESH:D009362 | Neoplasm Metastasis | Diethylnitrosamine | 6.55 | 9029167 3581430 | |
| MESH:D009362 | Neoplasm Metastasis | Disulfiram | 6.55 | 15367699 | |
| MESH:D009362 | Neoplasm Metastasis | Indomethacin | 6.55 | 11053908 11239499 16537180 | |
| MESH:D009362 | Neoplasm Metastasis | quinoline | 6.55 | 598648 | |
| MESH:D009369 | Neoplasms | Aspartame | 26.72 | 16507461 | |
| MESH:D009369 | Neoplasms | Benzo(a)pyrene | 26.72 | 11141357 | |
| MESH:D009369 | Neoplasms | Disulfiram | 26.72 | 17079463 | |
| MESH:D009369 | Neoplasms | Lindane | 26.72 | 12807735 16818664 | |
| MESH:D009369 | Neoplasms | Mirex | 26.72 | 8722114 | |
| MESH:D009369 | Neoplasms | Nicotine | 26.72 | 16365874 | |
| MESH:D009369 | Neoplasms | Oleanolic Acid | 26.72 | 8847885 | |
| MESH:D009369 | Neoplasms | Quercetin | 26.72 | 15185748 | |
| MESH:D009369 | Neoplasms | sodium arsenite | 26.72 | 11559025 | |
| MESH:D009369 | Neoplasms | Tetrachloroethylene | 26.72 | 11911487 | |
| MESH:D009369 | Neoplasms | Tretinoin | 26.72 | 16594593 16946489 | |
| MESH:D009369 | Neoplasms | Trichloroethylene | 26.72 | 11911487 | |
| MESH:D009369 | Neoplasms | Urethane | 26.72 | 15625555 | |
| MESH:D009369 | Neoplasms | Vinyl Chloride | 26.72 | 11911487 | |
| MESH:D009374 | Neoplasms, Experimental | 1,3-butadiene | 17.78 | 9488045 9205081 8764131 | |
| MESH:D009374 | Neoplasms, Experimental | erythritol anhydride | 17.78 | 10925838 | |
| MESH:D009374 | Neoplasms, Experimental | Indomethacin | 17.78 | 10663608 15625704 | |
| MESH:D009374 | Neoplasms, Experimental | resveratrol | 17.78 | 8985016 | |
| MESH:D009374 | Neoplasms, Experimental | sodium arsenite | 17.78 | 20056578 | |
| MESH:D009374 | Neoplasms, Experimental | Urethane | 17.78 | 15582191 | |
| MESH:D009376 | Neoplasms, Hormone-Dependent | Curcumin | 3.10 | 12497104 | |
| MESH:D018301 | Neoplasms, Mesothelial | Pentachlorophenol | 5.19 | 10696769 | |
| MESH:D009389 | Neovascularization, Pathologic | Disulfiram | 9.09 | 15367699 | |
| MESH:D009389 | Neovascularization, Pathologic | Estradiol | 9.09 | 17289903 | |
| MESH:D009389 | Neovascularization, Pathologic | Nicotine | 9.09 | 16365874 | |
| MESH:D009402 | Nephrosis, Lipoid | Cyclosporine | 2.98 | 17954296 | |
| MESH:D009404 | Nephrotic Syndrome | Cyclosporine | 2.02 | 19348381 18481113 | |
| MESH:D009410 | Nerve Degeneration | Acrylamide | 10.26 | 11264303 12387366 12387367 | |
| MESH:D009410 | Nerve Degeneration | Maneb | 10.26 | 16893418 15350641 | |
| MESH:D009410 | Nerve Degeneration | mangiferin | 10.26 | 17433543 | |
| MESH:D009410 | Nerve Degeneration | Paraquat | 10.26 | 16893418 | |
| MESH:D009422 | Nervous System Diseases | Acrylamide | 3.72 | 12164553 12507653 | |
| MESH:D009421 | Nervous System Malformations | Estradiol | 8.44 | 16427766 11399458 | |
| MESH:D009421 | Nervous System Malformations | Tetrachlorodibenzodioxin | 8.44 | 14600291 | |
| MESH:D009421 | Nervous System Malformations | Tretinoin | 8.44 | 9125849 | |
| MESH:D009423 | Nervous System Neoplasms | Curcumin | 4.17 | 18462866 | |
| MESH:D009436 | Neural Tube Defects | Arsenic | 20.70 | 16620997 | |
| MESH:D009436 | Neural Tube Defects | arsenic trioxide | 20.70 | 10525206 | |
| MESH:D009436 | Neural Tube Defects | Benzene | 20.70 | 15643154 | |
| MESH:D009436 | Neural Tube Defects | ochratoxin A | 20.70 | 20036863 | |
| MESH:D009436 | Neural Tube Defects | Phenytoin | 20.70 | 9118846 | |
| MESH:D009436 | Neural Tube Defects | sodium arsenite | 20.70 | 12854658 | |
| MESH:D009436 | Neural Tube Defects | Tretinoin | 20.70 | 9142499 | |
| MESH:D009436 | Neural Tube Defects | Vitamin A | 20.70 | 17400914 | |
| MESH:D019954 | Neurobehavioral Manifestations | Plant Extracts | 3.78 | 17168769 | |
| MESH:D009447 | Neuroblastoma | 1,3-butadiene | 3.96 | 15814359 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 9.90 | 18514411 | |
| MESH:D019636 | Neurodegenerative Diseases | Diethylnitrosamine | 9.90 | 20387270 | |
| MESH:D019636 | Neurodegenerative Diseases | Indomethacin | 9.90 | 12349958 | |
| MESH:D019636 | Neurodegenerative Diseases | resveratrol | 9.90 | 17652729 | |
| MESH:D020078 | Neurogenic Inflammation | Arsenic | 10.02 | 17056641 | |
| MESH:D020078 | Neurogenic Inflammation | Quercetin | 10.02 | 17929310 | |
| MESH:D020078 | Neurogenic Inflammation | resveratrol | 10.02 | 17929310 | |
| MESH:D009461 | Neurologic Manifestations | Diethylnitrosamine | 3.66 | 20387270 | |
| MESH:D020258 | Neurotoxicity Syndromes | 3-xylene | 5.28 | 7820390 8907413 | |
| MESH:D020258 | Neurotoxicity Syndromes | Disulfiram | 5.28 | 11005259 | |
| MESH:D052556 | Niemann-Pick Disease, Type C | perfluorooctanoic acid | 3.55 | 9802331 | |
| MESH:D009669 | Nose Neoplasms | 1,4-dioxane | 8.07 | 9385384 | |
| MESH:D009669 | Nose Neoplasms | 2,6-xylidine | 8.07 | 10463772 9385384 11442016 10945294 | |
| MESH:D009669 | Nose Neoplasms | Ethylene Dibromide | 8.07 | 9385384 | |
| MESH:D009765 | Obesity | Ascorbic Acid | 5.15 | 17217161 | |
| MESH:D009765 | Obesity | Curcumin | 5.15 | 19297423 | |
| MESH:D009765 | Obesity | Dietary Fats | 5.15 | 20518802 11836018 20132043 16723640 17217161 18457598 19632207 18674790 21332399 | |
| MESH:D009765 | Obesity | Plant Extracts | 5.15 | 20132043 19056576 | |
| MESH:D007752 | Obstetric Labor, Premature | Indomethacin | 3.71 | 6374098 | |
| MESH:D009784 | Occupational Diseases | Benzene | 5.54 | 15727169 16737584 17119257 15913788 17178637 15935809 15576619 15612468 17479406 | |
| MESH:D009784 | Occupational Diseases | Vinyl Chloride | 5.54 | 12061072 | |
| MESH:D010003 | Osteoarthritis | Aspartame | 6.64 | 9630831 | |
| MESH:D010003 | Osteoarthritis | Aspirin | 6.64 | 7009135 | |
| MESH:D010003 | Osteoarthritis | Indomethacin | 6.64 | 7009135 | |
| MESH:D010009 | Osteochondrodysplasias | Thiram | 4.32 | 15899490 17954590 15518828 | |
| MESH:D010018 | Osteomalacia | Phenobarbital | 7.34 | 17016548 | |
| MESH:D010018 | Osteomalacia | Phenytoin | 7.34 | 17016548 | |
| MESH:D010024 | Osteoporosis | Calcium | 4.01 | 17882678 | |
| MESH:D010024 | Osteoporosis | Curcumin | 4.01 | 18719352 | |
| MESH:D015663 | Osteoporosis, Postmenopausal | Drugs, Chinese Herbal | 9.24 | 16548355 | |
| MESH:D015663 | Osteoporosis, Postmenopausal | Quercetin | 9.24 | 19495926 | |
| MESH:D015663 | Osteoporosis, Postmenopausal | resveratrol | 9.24 | 17513867 | |
| MESH:D012516 | Osteosarcoma | Disulfiram | 3.93 | 18047805 | |
| MESH:D010051 | Ovarian Neoplasms | 1,3-butadiene | 27.14 | 2208121 | |
| MESH:D010051 | Ovarian Neoplasms | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | 27.14 | 16211241 | |
| MESH:D010051 | Ovarian Neoplasms | Arsenic | 27.14 | 17306315 | |
| MESH:D010051 | Ovarian Neoplasms | arsenic trioxide | 27.14 | 16624393 19769630 12452020 | |
| MESH:D010051 | Ovarian Neoplasms | Benzene | 27.14 | 12562636 | |
| MESH:D010051 | Ovarian Neoplasms | Curcumin | 27.14 | 18462866 19020741 | |
| MESH:D010051 | Ovarian Neoplasms | Disulfiram | 27.14 | 17026967 | |
| MESH:D010051 | Ovarian Neoplasms | Estradiol | 27.14 | 19401270 | |
| MESH:D010051 | Ovarian Neoplasms | Progesterone | 27.14 | 16525653 17393432 | |
| MESH:D010051 | Ovarian Neoplasms | Quercetin | 27.14 | 19005980 | |
| MESH:D010051 | Ovarian Neoplasms | sodium arsenite | 27.14 | 15276417 17306315 | |
| MESH:D010051 | Ovarian Neoplasms | Tretinoin | 27.14 | 16936753 | |
| MESH:D010051 | Ovarian Neoplasms | Urethane | 27.14 | 16391232 | |
| MESH:D010146 | Pain | Acetaminophen | 13.45 | 16870215 | |
| MESH:D010146 | Pain | Aspartame | 13.45 | 9630831 | |
| MESH:D010146 | Pain | Aspirin | 13.45 | 6995502 6363464 | |
| MESH:D010146 | Pain | Indomethacin | 13.45 | 17440234 13679232 17627676 3291741 | |
| MESH:D010146 | Pain | Phenol | 13.45 | 17610455 | |
| MESH:D010146 | Pain | Phenytoin | 13.45 | 15215642 | |
| MESH:D010146 | Pain | Tretinoin | 13.45 | 16870215 | |
| MESH:D010149 | Pain, Postoperative | Indomethacin | 7.06 | 18702446 12538197 | |
| MESH:D010149 | Pain, Postoperative | Ketamine | 7.06 | 11554966 | |
| MESH:D010190 | Pancreatic Neoplasms | 2,2-dichloro-1,1,1-trifluoroethane | 23.20 | 7601319 | |
| MESH:D010190 | Pancreatic Neoplasms | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 23.20 | 12384795 | |
| MESH:D010190 | Pancreatic Neoplasms | arsenic trioxide | 23.20 | 15580305 | |
| MESH:D010190 | Pancreatic Neoplasms | Curcumin | 23.20 | 19401701 17440100 19196508 | |
| MESH:D010190 | Pancreatic Neoplasms | Diethylnitrosamine | 23.20 | 16540662 | |
| MESH:D010190 | Pancreatic Neoplasms | Ethanol | 23.20 | 12384795 | |
| MESH:D010190 | Pancreatic Neoplasms | Phenobarbital | 23.20 | 16965848 | |
| MESH:D010190 | Pancreatic Neoplasms | Quercetin | 23.20 | 16965848 | |
| MESH:D010190 | Pancreatic Neoplasms | Reactive Oxygen Species | 23.20 | 15580305 | |
| MESH:D010190 | Pancreatic Neoplasms | Tetradecanoylphorbol Acetate | 23.20 | 15976015 | |
| MESH:D010190 | Pancreatic Neoplasms | Tretinoin | 23.20 | 15976015 | |
| MESH:D010195 | Pancreatitis | Indomethacin | 2.66 | 17883296 15028970 | |
| MESH:D010212 | Papilloma | cumene hydroperoxide | 7.96 | 12065085 17234724 | |
| MESH:D010212 | Papilloma | Plant Extracts | 7.96 | 16517061 15173996 | |
| MESH:D010212 | Papilloma | Tetradecanoylphorbol Acetate | 7.96 | 12065085 18922899 18404319 8330346 | |
| MESH:D010235 | Paraganglioma | arsenic trioxide | 2.81 | 19927285 | |
| MESH:D010243 | Paralysis | Zoxazolamine | 5.49 | 16109766 | |
| MESH:D010257 | Paraneoplastic Syndromes | Indomethacin | 4.26 | 16537180 | |
| MESH:D010300 | Parkinson Disease | marker/mechanism | 16510128 | ||
| MESH:D010300 | Parkinson Disease | Atrazine | 9.62 | 17218051 | |
| MESH:D010300 | Parkinson Disease | Desipramine | 9.62 | 10965161 | |
| MESH:D010300 | Parkinson Disease | Ditiocarb | 9.62 | 11445065 | |
| MESH:D010300 | Parkinson Disease | Maneb | 9.62 | 12911755 15824117 11124998 16140633 16510128 | |
| MESH:D010300 | Parkinson Disease | mangiferin | 9.62 | 17433543 | |
| MESH:D010300 | Parkinson Disease | Paraquat | 9.62 | 11124998 12911755 16140633 11445065 11181820 16510128 15824117 15451049 | |
| MESH:D010302 | Parkinson Disease, Secondary | Paraquat | 3.04 | 16190885 | |
| MESH:D020734 | Parkinsonian Disorders | Indomethacin | 2.85 | 12349958 | |
| MESH:D051302 | Paroxysmal Hemicrania | Indomethacin | 4.26 | 11903285 | |
| MESH:D010382 | Peliosis Hepatis | 1-Naphthylisothiocyanate | 8.97 | 20133375 | |
| MESH:D010382 | Peliosis Hepatis | Tetrachlorodibenzodioxin | 8.97 | 12520081 | |
| MESH:D010392 | Pemphigus | Phenol | 4.98 | 17163923 16522979 | |
| MESH:D010437 | Peptic Ulcer | Indomethacin | 9.08 | 11148446 | |
| MESH:D010437 | Peptic Ulcer | Sulfhydryl Compounds | 9.08 | 1488453 | |
| MESH:D010438 | Peptic Ulcer Hemorrhage | Aspirin | 4.10 | 11156591 | |
| MESH:D010518 | Periodontitis | Indomethacin | 7.60 | 17225004 | |
| MESH:D010518 | Periodontitis | mangiferin | 7.60 | 19026997 | |
| MESH:D010523 | Peripheral Nervous System Diseases | Acrylamide | 9.09 | 11510240 | |
| MESH:D010523 | Peripheral Nervous System Diseases | Arsenic | 9.09 | 16093927 | |
| MESH:D010523 | Peripheral Nervous System Diseases | n-hexane | 9.09 | 16484137 | |
| MESH:D016491 | Peripheral Vascular Diseases | Arsenic | 3.55 | 16905509 6392382 15371236 | |
| MESH:D010538 | Peritonitis | Ozone | 2.76 | 16369182 | |
| MESH:D020795 | Photophobia | Aspirin | 4.30 | 15240983 | |
| MESH:D010864 | Pilonidal Sinus | Phenol | 4.98 | 19655223 15622588 | |
| MESH:D010911 | Pituitary Neoplasms | Urethane | 4.01 | 16391232 | |
| MESH:D011014 | Pneumonia | Lipopolysaccharides | 10.40 | 12224865 11605937 | |
| MESH:D011014 | Pneumonia | Ozone | 10.40 | 18381685 18929643 18007984 | |
| MESH:D011014 | Pneumonia | Paraquat | 10.40 | 12504350 | |
| MESH:D011015 | Pneumonia, Aspiration | Nitric Oxide | 3.91 | 18573544 | |
| MESH:D011041 | Poisoning | Phenol | 3.44 | 8825745 | |
| MESH:D017689 | Polydactyly | Phenytoin | 3.75 | 9212184 | |
| MESH:D017285 | Polymyositis | Vinyl Chloride | 5.40 | 11642524 | |
| MESH:D017119 | Porphyria Cutanea Tarda | Hexachlorobenzene | 6.52 | 9918132 | |
| MESH:D017119 | Porphyria Cutanea Tarda | Tetrachlorodibenzodioxin | 6.52 | 18163543 | |
| MESH:D011164 | Porphyrias | 1,2,4-trichlorobenzene | 5.35 | 6636202 | |
| MESH:D011230 | Precancerous Conditions | 1-phenylazo-2-naphthol | 23.76 | 2563599 | |
| MESH:D011230 | Precancerous Conditions | Azoxymethane | 23.76 | 12458338 19056647 14668109 | |
| MESH:D011230 | Precancerous Conditions | bromodichloromethane | 23.76 | 14668109 | |
| MESH:D011230 | Precancerous Conditions | Cyclosporine | 23.76 | 12371664 | |
| MESH:D011230 | Precancerous Conditions | Diethylnitrosamine | 23.76 | 2563599 | |
| MESH:D011230 | Precancerous Conditions | Phenobarbital | 23.76 | 2563599 | |
| MESH:D011230 | Precancerous Conditions | Quercetin | 23.76 | 19056647 | |
| MESH:D054198 | Precursor Cell Lymphoblastic Leukemia-Lymphoma | Dexamethasone | 2.55 | 21297632 | |
| MESH:D011248 | Pregnancy Complications | bromodichloromethane | 4.70 | 17344021 14657523 12970577 | |
| MESH:D047928 | Premature Birth | Indomethacin | 3.71 | 17000239 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | perfluorooctanoic acid | 11.81 | 17132714 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | resveratrol | 11.81 | 16679765 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | Tetrachlorodibenzodioxin | 11.81 | 11118676 11896295 11399792 11222880 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | vinclozolin | 11.81 | 18042343 18220299 19015723 | |
| MESH:D011469 | Prostatic Diseases | vinclozolin | 3.50 | 18220299 | |
| MESH:D019048 | Prostatic Intraepithelial Neoplasia | Estradiol | 6.43 | 20887781 | |
| MESH:D019048 | Prostatic Intraepithelial Neoplasia | Testosterone | 6.43 | 20887781 | |
| MESH:D011471 | Prostatic Neoplasms | marker/mechanism | 12771559 | ||
| MESH:D011471 | Prostatic Neoplasms | Androgens | 3.66 | 15389811 16998812 17909013 | |
| MESH:D011471 | Prostatic Neoplasms | Arsenic | 3.66 | 16140617 | |
| MESH:D011471 | Prostatic Neoplasms | arsenic trioxide | 3.66 | 19131511 | |
| MESH:D011471 | Prostatic Neoplasms | Benzo(a)pyrene | 3.66 | 17292933 | |
| MESH:D011471 | Prostatic Neoplasms | Curcumin | 3.66 | 18226269 12497104 11398177 18156803 15129424 18769126 10851300 | |
| MESH:D011471 | Prostatic Neoplasms | diallyl disulfide | 3.66 | 16691315 | |
| MESH:D011471 | Prostatic Neoplasms | Disulfiram | 3.66 | 19789329 | |
| MESH:D011471 | Prostatic Neoplasms | Estradiol | 3.66 | 16740699 | |
| MESH:D011471 | Prostatic Neoplasms | Ketoconazole | 3.66 | 17404083 | |
| MESH:D011471 | Prostatic Neoplasms | Lindane | 3.66 | 12661182 14688026 | |
| MESH:D011471 | Prostatic Neoplasms | Plant Extracts | 3.66 | 17804756 14666653 | |
| MESH:D011471 | Prostatic Neoplasms | Quercetin | 3.66 | 17292933 14715546 | |
| MESH:D011471 | Prostatic Neoplasms | resveratrol | 3.66 | 17718901 17804756 15767336 17636462 16731767 17675339 | |
| MESH:D011471 | Prostatic Neoplasms | sodium arsenite | 3.66 | 16039940 | |
| MESH:D011471 | Prostatic Neoplasms | Thiram | 3.66 | 19789329 | |
| MESH:D011472 | Prostatitis | vinclozolin | 3.50 | 18629315 | |
| MESH:D011507 | Proteinuria | Arsenic | 7.78 | 21343184 | |
| MESH:D011507 | Proteinuria | Indomethacin | 7.78 | 11849393 | |
| MESH:D011507 | Proteinuria | Tretinoin | 7.78 | 16636307 | |
| MESH:D019310 | Pseudolymphoma | Phenobarbital | 7.75 | 12752131 | |
| MESH:D019310 | Pseudolymphoma | Phenytoin | 7.75 | 8603615 1419762 12752131 | |
| MESH:D011565 | Psoriasis | Cyclosporine | 3.71 | 16882103 | |
| MESH:D011565 | Psoriasis | Methoxsalen | 3.71 | 16259964 | |
| MESH:D011618 | Psychotic Disorders | Thioridazine | 4.09 | 16882315 | |
| MESH:D011625 | Pterygium | Tretinoin | 3.35 | 16723453 | |
| MESH:D029424 | Pulmonary Disease, Chronic Obstructive | Theophylline | 3.93 | 18983928 | |
| MESH:D011656 | Pulmonary Emphysema | Curcumin | 3.21 | 19168576 | |
| MESH:D011657 | Pulmonary Eosinophilia | Ascorbic Acid | 3.88 | 14606601 | |
| MESH:D011658 | Pulmonary Fibrosis | Drugs, Chinese Herbal | 3.44 | 16987627 | |
| MESH:D011658 | Pulmonary Fibrosis | Paraquat | 3.44 | 17997886 16324872 | |
| MESH:D011833 | Radiation Injuries, Experimental | mangiferin | 4.95 | 15830843 | |
| MESH:D011928 | Raynaud Disease | Vinyl Chloride | 4.72 | 16977343 | |
| MESH:D012003 | Rectal Fistula | Drugs, Chinese Herbal | 4.51 | 15043669 | |
| MESH:D012004 | Rectal Neoplasms | bromodichloromethane | 4.60 | 17535441 | |
| MESH:D051436 | Renal Insufficiency, Chronic | resveratrol | 4.12 | 16325855 | |
| MESH:D015427 | Reperfusion Injury | resveratrol | 2.39 | 16314181 16317513 15827377 17058453 17520802 | |
| MESH:D012128 | Respiratory Distress Syndrome, Adult | Curcumin | 7.54 | 10666014 18379247 | |
| MESH:D012128 | Respiratory Distress Syndrome, Adult | Dexamethasone | 7.54 | 11700416 18379247 | |
| MESH:D012128 | Respiratory Distress Syndrome, Adult | Paraquat | 7.54 | 11700416 | |
| MESH:D012127 | Respiratory Distress Syndrome, Newborn | Vitamin A | 4.36 | 16877224 | |
| MESH:D012130 | Respiratory Hypersensitivity | Lipopolysaccharides | 2.64 | 10835634 | |
| MESH:D012135 | Respiratory Sounds | Atrazine | 8.35 | 11874814 | |
| MESH:D012135 | Respiratory Sounds | Paraquat | 8.35 | 11874814 | |
| MESH:D012135 | Respiratory Sounds | Parathion | 8.35 | 17119214 11874814 | |
| MESH:D015619 | Respiratory System Abnormalities | Tetrachlorodibenzodioxin | 2.45 | 18990726 | |
| MESH:D012140 | Respiratory Tract Diseases | Parathion | 4.13 | 17119214 | |
| MESH:D012162 | Retinal Degeneration | Paraquat | 2.68 | 16458197 | |
| MESH:D012174 | Retinitis Pigmentosa | Ascorbic Acid | 2.72 | 16849425 | |
| MESH:D012208 | Rhabdomyosarcoma | Tretinoin | 2.74 | 16283617 16116481 | |
| MESH:D012220 | Rhinitis | Acetaldehyde | 5.10 | 17050345 | |
| MESH:D012220 | Rhinitis | Aspirin | 5.10 | 12372130 | |
| MESH:D012221 | Rhinitis, Allergic, Perennial | Drugs, Chinese Herbal | 3.84 | 15015336 | |
| MESH:D012468 | Salivary Gland Neoplasms | Progesterone | 2.12 | 18045962 | |
| MESH:D012509 | Sarcoma | Curcumin | 8.68 | 18462866 | |
| MESH:D012509 | Sarcoma | Polysaccharides | 8.68 | 18753065 | |
| MESH:D012509 | Sarcoma | Vinyl Chloride | 8.68 | 12828392 | |
| MESH:D012512 | Sarcoma, Ewing's | arsenic trioxide | 2.60 | 16646077 | |
| MESH:D012554 | Schistosomiasis japonica | Quercetin | 4.08 | 16862918 | |
| MESH:D012555 | Schistosomiasis mansoni | Nitric Oxide | 4.07 | 9673227 | |
| MESH:D012559 | Schizophrenia | Ketamine | 3.81 | 20000043 | |
| MESH:D012595 | Scleroderma, Systemic | Vinyl Chloride | 4.45 | 14979077 | |
| MESH:D012640 | Seizures | 3-xylene | 21.63 | 8907413 6431079 | |
| MESH:D012640 | Seizures | Acrylonitrile | 21.63 | 20127315 | |
| MESH:D012640 | Seizures | Ethanol | 21.63 | 9754883 | |
| MESH:D012640 | Seizures | Isoniazid | 21.63 | 16107249 | |
| MESH:D012640 | Seizures | Lindane | 21.63 | 15475178 12842176 7539098 | |
| MESH:D012640 | Seizures | Midazolam | 21.63 | 10087439 | |
| MESH:D012640 | Seizures | Nicotine | 21.63 | 17873105 | |
| MESH:D012640 | Seizures | Phenobarbital | 21.63 | 11442880 3137016 4039156 16876388 | |
| MESH:D012640 | Seizures | Phenytoin | 21.63 | 10029267 3691417 11044598 9844417 3137016 15946322 19919933 16876388 | |
| MESH:D012640 | Seizures | Thiadiazoles | 21.63 | 19919933 | |
| MESH:D012640 | Seizures | Toluene | 21.63 | 6431079 9294310 | |
| MESH:D003294 | Seizures, Febrile | Phenobarbital | 3.38 | 6407741 | |
| MESH:D018805 | Sepsis | Curcumin | 2.83 | 18389075 | |
| MESH:D012735 | Sexual Dysfunction, Physiological | Testosterone | 4.74 | 16631401 | |
| MESH:D012772 | Shock, Septic | mangiferin | 3.83 | 15177305 | |
| MESH:D012851 | Sinus Thrombosis, Intracranial | Aspirin | 3.86 | 12269725 | |
| MESH:D012859 | Sjogren's Syndrome | Aspartame | 5.12 | 16800424 | |
| MESH:D012871 | Skin Diseases | Arsenic | 4.20 | 17050553 16353154 15952646 19834688 17938729 17453740 16702368 16759981 17548696 6392382 18709164 | |
| MESH:D012871 | Skin Diseases | Ascorbic Acid | 4.20 | 18709164 | |
| MESH:D012871 | Skin Diseases | Vitamin A | 4.20 | 18709164 | |
| MESH:D012878 | Skin Neoplasms | Arsenic | 30.62 | 17050553 15504454 16251483 17976673 17029826 19538983 | |
| MESH:D012878 | Skin Neoplasms | Benzo(a)pyrene | 30.62 | 10029692 19755658 | |
| MESH:D012878 | Skin Neoplasms | cumene hydroperoxide | 30.62 | 8532709 17234724 12065085 | |
| MESH:D012878 | Skin Neoplasms | Mirex | 30.62 | 1732051 8508502 | |
| MESH:D012878 | Skin Neoplasms | Plant Extracts | 30.62 | 16517061 15173996 | |
| MESH:D012878 | Skin Neoplasms | resveratrol | 30.62 | 8985016 15837718 | |
| MESH:D012878 | Skin Neoplasms | sodium arsenite | 30.62 | 18572023 19524636 | |
| MESH:D012878 | Skin Neoplasms | tert-Butylhydroperoxide | 30.62 | 8532709 | |
| MESH:D012878 | Skin Neoplasms | Tetrachlorodibenzodioxin | 30.62 | 16192470 | |
| MESH:D012878 | Skin Neoplasms | Tetradecanoylphorbol Acetate | 30.62 | 8985016 11807781 18404319 12065085 8330346 | |
| MESH:D012878 | Skin Neoplasms | Tretinoin | 30.62 | 16467112 | |
| MESH:D012878 | Skin Neoplasms | Urethane | 30.62 | 11807781 | |
| MESH:D012878 | Skin Neoplasms | YH 439 | 30.62 | 10029692 | |
| MESH:D012893 | Sleep Disorders | Caffeine | 6.97 | 19395429 | |
| MESH:D012893 | Sleep Disorders | Midazolam | 6.97 | 6138072 | |
| MESH:D007319 | Sleep Initiation and Maintenance Disorders | Caffeine | 6.22 | 17225163 | |
| MESH:D007319 | Sleep Initiation and Maintenance Disorders | Midazolam | 6.22 | 6138071 | |
| MESH:D013088 | Spermatocele | Phenol | 4.19 | 18646496 | |
| MESH:D013119 | Spinal Cord Injuries | Progesterone | 2.86 | 15862959 16503802 | |
| MESH:D016135 | Spinal Dysraphism | sodium arsenite | 2.58 | 12854658 | |
| MESH:D013158 | Splenic Diseases | aniline | 14.56 | 15694462 | |
| MESH:D013158 | Splenic Diseases | Dimethylnitrosamine | 14.56 | 12587719 | |
| MESH:D013158 | Splenic Diseases | Grape Seed Proanthocyanidins | 14.56 | 12587719 | |
| MESH:D013160 | Splenic Neoplasms | Pentachlorophenol | 4.85 | 10696769 | |
| MESH:D013262 | Stevens-Johnson Syndrome | Phenytoin | 3.76 | 20235791 | |
| MESH:D013272 | Stomach Diseases | Dexamethasone | 9.01 | 15472012 | |
| MESH:D013272 | Stomach Diseases | Indomethacin | 9.01 | 10192188 17160473 10486359 17207306 10215738 15472012 16113693 17638125 16184426 18545984 15038085 16280098 18209964 | |
| MESH:D013272 | Stomach Diseases | Omeprazole | 9.01 | 18545984 | |
| MESH:D013274 | Stomach Neoplasms | 1,3-butadiene | 17.06 | 11397402 2208121 | |
| MESH:D013274 | Stomach Neoplasms | Acrylonitrile | 17.06 | 12562636 | |
| MESH:D013274 | Stomach Neoplasms | arsenic trioxide | 17.06 | 17007042 | |
| MESH:D013274 | Stomach Neoplasms | Benzene | 17.06 | 12562636 | |
| MESH:D013274 | Stomach Neoplasms | Benzo(a)pyrene | 17.06 | 2093021 20155912 | |
| MESH:D013274 | Stomach Neoplasms | Diethylnitrosamine | 17.06 | 18456281 | |
| MESH:D013274 | Stomach Neoplasms | Dimethylnitrosamine | 17.06 | 16033868 | |
| MESH:D013274 | Stomach Neoplasms | Docosahexaenoic Acids | 17.06 | 19015929 | |
| MESH:D013274 | Stomach Neoplasms | Drugs, Chinese Herbal | 17.06 | 18339527 | |
| MESH:D013274 | Stomach Neoplasms | Ethanol | 17.06 | 18456281 | |
| MESH:D013274 | Stomach Neoplasms | Ethylene Dibromide | 17.06 | 3768853 | |
| MESH:D013274 | Stomach Neoplasms | Indomethacin | 17.06 | 15609394 | |
| MESH:D013274 | Stomach Neoplasms | nitrosobenzylmethylamine | 17.06 | 12958204 17575124 | |
| MESH:D013274 | Stomach Neoplasms | Tretinoin | 17.06 | 17261132 | |
| MESH:D013274 | Stomach Neoplasms | Vinyl Chloride | 17.06 | 12562636 | |
| MESH:D013276 | Stomach Ulcer | Ascorbic Acid | 20.37 | 18726076 | |
| MESH:D013276 | Stomach Ulcer | Curcumin | 20.37 | 16631530 19188055 | |
| MESH:D013276 | Stomach Ulcer | Dexamethasone | 20.37 | 15138204 | |
| MESH:D013276 | Stomach Ulcer | Ethanol | 20.37 | 17189318 16755016 9211565 17918041 9562338 11906479 | |
| MESH:D013276 | Stomach Ulcer | Indomethacin | 20.37 | 15104355 11906479 12500499 18193104 16150113 17918041 10423059 17657623 15255614 16169175 16252198 11595431 10878458 17977527 18431645 16631530 1323529 16934674 17135157 14567935 12077510 18237397 17627676 12467913 10750652 12787963 16397915 12498302 11145282 18209962 15138204 17654042 16755016 18726076 18543354 18087811 11523592 11595415 17895592 18299717 11729361 18181030 | |
| MESH:D013276 | Stomach Ulcer | mangiferin | 20.37 | 17918041 | |
| MESH:D013276 | Stomach Ulcer | Nitric Oxide | 20.37 | 15138204 | |
| MESH:D013276 | Stomach Ulcer | Omeprazole | 20.37 | 11906479 10750652 17977527 18237397 16755016 15991576 | |
| MESH:D013276 | Stomach Ulcer | Plant Extracts | 20.37 | 18193104 17135157 15255614 12787963 18237397 | |
| MESH:D020521 | Stroke | Ascorbic Acid | 5.12 | 16517955 16403987 | |
| MESH:D020521 | Stroke | Aspirin | 5.12 | 16403987 | |
| OMIM:601367 | STROKE, ISCHEMIC | resveratrol | 3.16 | 16321402 | |
| MESH:D013345 | Subarachnoid Hemorrhage | Drugs, Chinese Herbal | 4.31 | 17634840 | |
| MESH:D013375 | Substance Withdrawal Syndrome | Ethanol | 2.96 | 9754883 | |
| MESH:D013436 | Sulfhemoglobinemia | Phenacetin | 5.09 | 978859 | |
| MESH:D017180 | Tachycardia, Ventricular | Thioridazine | 4.34 | 20210726 | |
| MESH:D013705 | Temporomandibular Joint Disorders | Plant Extracts | 8.46 | 17997062 | |
| MESH:D013705 | Temporomandibular Joint Disorders | polyphenols | 8.46 | 17997062 | |
| MESH:D013733 | Testicular Diseases | Acrylamide | 13.23 | 15864552 | |
| MESH:D013733 | Testicular Diseases | phenethyl isothiocyanate | 13.23 | 15864552 | |
| MESH:D013733 | Testicular Diseases | pyrazole | 13.23 | 6499806 | |
| MESH:D013733 | Testicular Diseases | Toluene | 13.23 | 10514026 10048760 | |
| MESH:D013736 | Testicular Neoplasms | 2,2-dichloro-1,1,1-trifluoroethane | 4.97 | 7601319 | |
| MESH:D013742 | Tetanus | Midazolam | 5.18 | 2903605 | |
| MESH:D013921 | Thrombocytopenia | 1-Naphthylisothiocyanate | 8.95 | 20133375 | |
| MESH:D013921 | Thrombocytopenia | Aspartame | 8.95 | 17534100 | |
| MESH:D013921 | Thrombocytopenia | Lipopolysaccharides | 8.95 | 15821434 | |
| MESH:D013927 | Thrombosis | Aspirin | 3.26 | 17672075 | |
| MESH:D013953 | Thymus Neoplasms | Benzene | 3.53 | 10850423 | |
| MESH:D013959 | Thyroid Diseases | Tetrachlorodibenzodioxin | 2.45 | 12697716 | |
| MESH:D013964 | Thyroid Neoplasms | arsenic trioxide | 15.72 | 19014326 | |
| MESH:D013964 | Thyroid Neoplasms | Diethylnitrosamine | 15.72 | 7505956 | |
| MESH:D013964 | Thyroid Neoplasms | diethylthiourea | 15.72 | 1907225 11940454 | |
| MESH:D013964 | Thyroid Neoplasms | Indomethacin | 15.72 | 14736730 18791128 11352223 | |
| MESH:D013964 | Thyroid Neoplasms | Phenobarbital | 15.72 | 1399818 | |
| MESH:D013964 | Thyroid Neoplasms | Tretinoin | 15.72 | 17045167 16026305 | |
| MESH:D013964 | Thyroid Neoplasms | triadimefon | 15.72 | 17178689 | |
| MESH:D013978 | Tibial Fractures | Estradiol | 3.23 | 19048282 | |
| OMIM:188890 | TOBACCO ADDICTION, SUSCEPTIBILITY TO | Nicotine | 3.55 | 11259349 16720336 16785264 | |
| MESH:D014029 | Tobacco Use Disorder | Nicotine | 4.04 | 17979512 18305452 15735609 18041664 | |
| MESH:D014062 | Tongue Neoplasms | resveratrol | 5.57 | 16227395 | |
| MESH:D014062 | Tongue Neoplasms | Tretinoin | 5.57 | 16051514 | |
| MESH:D016171 | Torsades de Pointes | arsenic trioxide | 2.56 | 15213294 | |
| MESH:D014202 | Tremor | 2-cresol | 4.95 | 12820538 | |
| MESH:D014235 | Trichinellosis | mangiferin | 4.60 | 14669257 | |
| MESH:D014277 | Trigeminal Neuralgia | Phenol | 4.98 | 16527771 10223447 | |
| MESH:D014376 | Tuberculosis | Isoniazid | 7.26 | 16770646 15236969 17720495 17950035 15673755 18397238 | |
| MESH:D014376 | Tuberculosis | Rifampin | 7.26 | 15236969 18397238 | |
| MESH:D014376 | Tuberculosis | Tretinoin | 7.26 | 16040207 | |
| MESH:D014456 | Ulcer | Indomethacin | 3.47 | 17380554 10574470 | |
| MESH:D001749 | Urinary Bladder Neoplasms | 2,6-xylidine | 21.20 | 15467031 | |
| MESH:D001749 | Urinary Bladder Neoplasms | 2-Acetylaminofluorene | 21.20 | 15289314 1399818 15867355 | |
| MESH:D001749 | Urinary Bladder Neoplasms | 2-nitroanisole | 21.20 | 14729594 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Arsenic | 21.20 | 17976673 19429237 19322015 17306315 11144890 18640142 15987713 | |
| MESH:D001749 | Urinary Bladder Neoplasms | arsenic trioxide | 21.20 | 12845720 20435036 12973940 11780464 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Benzo(a)pyrene | 21.20 | 17053015 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Curcumin | 21.20 | 18593936 | |
| MESH:D001749 | Urinary Bladder Neoplasms | dibutylnitrosamine | 21.20 | 12706858 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Phenacetin | 21.20 | 11144890 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Quercetin | 21.20 | 16720314 | |
| MESH:D001749 | Urinary Bladder Neoplasms | sodium arsenite | 21.20 | 11723127 16452187 16712894 17306315 | |
| MESH:D014565 | Urogenital Neoplasms | Curcumin | 3.82 | 18462866 | |
| MESH:D014581 | Urticaria | Acetaminophen | 4.50 | 10982225 | |
| MESH:D014581 | Urticaria | Aspirin | 4.50 | 20485159 10982225 | |
| MESH:D002583 | Uterine Cervical Neoplasms | resveratrol | 8.38 | 17473185 | |
| MESH:D002583 | Uterine Cervical Neoplasms | sodium arsenite | 8.38 | 11813266 | |
| MESH:D002583 | Uterine Cervical Neoplasms | Tretinoin | 8.38 | 16129372 | |
| MESH:D014594 | Uterine Neoplasms | Benzene | 5.35 | 12562636 | |
| MESH:D014594 | Uterine Neoplasms | resveratrol | 5.35 | 17044934 | |
| MESH:D014604 | Uveal Neoplasms | Tretinoin | 3.16 | 16752155 | |
| MESH:D014605 | Uveitis | Cyclosporine | 6.97 | 1336536 | |
| MESH:D014605 | Uveitis | Dexamethasone | 6.97 | 1336536 | |
| MESH:D014652 | Vascular Diseases | Arsenic | 7.11 | 17056641 | |
| MESH:D014652 | Vascular Diseases | sodium arsenite | 7.11 | 17056641 | |
| MESH:D054079 | Vascular Malformations | Tetrachlorodibenzodioxin | 3.13 | 12125929 | |
| MESH:D019043 | Vascular Neoplasms | Urethane | 4.45 | 10620525 | |
| MESH:D018487 | Ventricular Dysfunction, Left | Plant Extracts | 5.91 | 18097624 | |
| MESH:D018487 | Ventricular Dysfunction, Left | resveratrol | 5.91 | 17488730 | |
| MESH:D020257 | Ventricular Remodeling | Plant Extracts | 3.88 | 18097624 | |
| MESH:D014802 | Vitamin A Deficiency | Vitamin A | 3.91 | 16146918 16960172 16175781 | |
| MESH:D014820 | Vitiligo | Methoxsalen | 6.85 | 16259964 | |
| MESH:D014820 | Vitiligo | Tretinoin | 6.85 | 16761959 | |
| MESH:D014839 | Vomiting | Indomethacin | 3.31 | 11897121 | |
| MESH:D014860 | Warts | Phenol | 4.64 | 19122958 | |
| MESH:D019282 | Wasting Syndrome | Tetrachlorodibenzodioxin | 2.79 | 15886252 | |
| MESH:D015430 | Weight Gain | Dietary Fats | 2.47 | 16723640 | |
| MESH:D009396 | Wilms Tumor | Tretinoin | 2.68 | 16287080 | |
| MESH:D014947 | Wounds and Injuries | Drugs, Chinese Herbal | 7.32 | 16313111 | |
| MESH:D014947 | Wounds and Injuries | Estrogens | 7.32 | 11172683 | |
| MESH:D014947 | Wounds and Injuries | Plant Extracts | 7.32 | 19894650 20213670 | |
| MESH:D014985 | Xerophthalmia | Cyclosporine | 2.98 | 17120751 |
| Pathway ID | Pathway Name |
|---|---|
| KEGG:00590 | Arachidonic acid metabolism |
| REACT:13433 | Biological oxidations |
| KEGG:00982 | Drug metabolism - cytochrome P450 |
| KEGG:00591 | Linoleic acid metabolism |
| KEGG:01100 | Metabolic pathways |
| KEGG:00980 | Metabolism of xenobiotics by cytochrome P450 |
| Releated gene ID | Related gene Name |
|---|---|
| PA129 | CYP2E1 |
| PA378 | NR1I2 |
| Releated disease ID | Related disease Name |
|---|---|
| PA443622 | Carcinoma, Non-Small-Cell Lung |
| PA445876 | Tobacco Use Disorder |
| PA444818 | Lung Neoplasms |
| PA444802 | Liver Diseases, Alcoholic |
| PA443937 | Drug Toxicity |
| PA444801 | Liver Diseases |
| PA445941 | Tuberculosis |
| PA443224 | Abnormalities, Drug-Induced |
| PA164925725 | Toxic liver disease |
| Releated drug ID | Related drug Name |
|---|---|
| PA164749136 | desflurane |
| PA449461 | enflurane |
| PA450106 | isoflurane |
| PA451341 | sevoflurane |
| PA449383 | docetaxel |
| PA448385 | amitriptyline |
| PA164746464 | bifonazole |
| PA10035 | bromazepam |
| PA448785 | carbamazepine |
| PA448964 | chlorpromazine |
| PA449050 | clonazepam |
| PA449057 | clotrimazole |
| PA449233 | desipramine |
| PA449283 | diazepam |
| PA449293 | diclofenac |
| PA164746010 | econazole |
| PA449533 | ethosuximide |
| PA449653 | fluconazole |
| PA164781320 | flunitrazepam |
| PA449676 | fluphenazine |
| PA449681 | flurazepam |
| PA449841 | haloperidol |
| PA449969 | imipramine |
| PA450132 | itraconazole |
| PA450146 | ketoconazole |
| PA164743145 | methsuximide |
| PA450494 | miconazole |
| PA10242 | nitrazepam |
| PA450657 | nortriptyline |
| PA164771230 | phensuximide |
| PA450947 | phenytoin |
| PA451666 | thioridazine |
| PA162630444 | eszopiclone |
| PA452609 | aflatoxin b1 |
| PA448015 | acetaminophen |
| PA165820585 | 1,7-dimethylxanthine |
| PA448710 | caffeine |
| PA451647 | theophylline |
| PA452614 | furafylline |
| PA451646 | theobromine |
| PA451954 | zidovudine |
| PA450112 | isoniazid |
| PA449165 | cyclophosphamide |
| PA449247 | dexamethasone |
| PA449552 | etoposide |
| PA450496 | midazolam |
| PA451611 | teniposide |
| PA450626 | nicotine |
| PA449014 | cisplatin |
| PA152031327 | geldanamycin |
| PA448971 | chlorzoxazone |
| PA448015 | acetaminophen |
| PA452604 | xenobiotics |
| PA448073 | ethanol |
| PA451668 | thiotepa |
| PA451089 | pravastatin |
| PA451250 | rifampin |
| PA450911 | phenobarbital |
| PA449845 | halothane |
| PA448073 | ethanol |
| PA451103 | primaquine |
| PA164712708 | Drugs For Treatment Of Tuberculosis |
| PA450913 | phenol |
| No data |
| Drugbank ID | Action | Drug Name | Description |
|---|---|---|---|
| DB00118 | - | S-Adenosylmethionine | Dietary supplement;Micronutrient |
| DB00143 | - | BSS Plus | Dietary supplement;Micronutrient |
| DB00158 | substrate | Folic Acid | Dietary supplement;Micronutrient;Vitamin B Complex;Hematinics |
| DB00170 | substrate | Menadione | Dietary supplement;Micronutrient;Antifibrinolytic Agents;Vitamins/minerals;Vitamins |
| DB00176 | substrate | Fluvoxamine | Anti-anxiety Agents;Selective Serotonin Reuptake Inhibitors (SSRIs);Antidepressive Agents;Serotonin Uptake Inhibitors;Antidepressive Agents, Second-Generation |
| DB00184 | inhibitor | Nicotine | Anti-craving Agents;Central Nervous System Agents;Autonomic drugs;Nicotinic Agonists;Ganglionic Stimulants |
| DB00201 | substrate | Wigraine Tab | Central Nervous System Stimulants;Anorexigenic Agents;Phosphodiesterase Inhibitors |
| DB00203 | inhibitor | Sildenafil | Vasodilator Agents;Phosphodiesterase Inhibitors |
| DB00208 | inhibitor | Ticlopidine | Platelet Aggregation Inhibitors;Fibrinolytic Agents |
| DB00215 | substrate | Citalopram | Antidepressants;Selective Serotonin Reuptake Inhibitors (SSRIs);Serotonin Uptake Inhibitors;Antidepressive Agents, Second-Generation |
| DB00228 | substrate | Enflurane | Anesthetics, Inhalation;General Anesthetics |
| DB00250 | substrate | Dapsone | Anti-Infective Agents;Anti-Infectives;Anti-inflammatory Agents;Antimalarials;Folic Acid Antagonists;Leprostatic Agents;Antimycobacterials |
| DB00257 | inhibitor | Lotrisone | Antifungal Agents;Anti-Infective Agents, Local;Growth Inhibitors |
| DB00259 | inhibitor | Triple Sulfa Bolus 240gr | Anti-Bacterial Agents;Homeopathic Agents;Sulfonamides |
| DB00277 | substrate | Theophylline rougier elixir | Vasodilator Agents;Phosphodiesterase Inhibitors;Bronchodilator Agents;Respiratory Smooth Muscle Relaxants |
| DB00316 | substrate | Zydone | Analgesics, Non-Narcotic;Antipyretics |
| DB00321 | inhibitor | Triavil Tab | Adrenergic Uptake Inhibitors;Analgesics, Non-Narcotic;Antidepressive Agents, Tricyclic |
| DB00347 | substrate | Trimethadione | Anticonvulsants |
| DB00356 | inhibitor | Parafon Forte Tablets | Muscle Relaxants, Central |
| DB00359 | substrate | Sulfadiazine | Anti-Infective Agents;Anti-Infectives;Antiprotozoals;Antiprotozoal Agents;Coccidiostats |
| DB00363 | inhibitor | Clozapine | Antipsychotics;Serotonin Antagonists;Antipsychotic Agents;GABA Antagonists |
| DB00371 | substrate | Equagesic Tablets | Anti-anxiety Agents;Hypnotics and Sedatives;Anticonvulsants;Muscle Relaxants, Central |
| DB00379 | substrate | Mexiletine | Anti-Arrhythmia Agents |
| DB00458 | inhibitor | Imipramine | Adrenergic Uptake Inhibitors;Antidepressive Agents, Tricyclic;Norepinephrine-Reuptake Inhibitors |
| DB00468 | substrate | Triogene for | Antimalarials;Analgesics, Non-Narcotic;Muscle Relaxants, Central |
| DB00472 | substrate | Fluoxetine | Selective Serotonin Reuptake Inhibitors (SSRIs);Antidepressants, Second-Generation;Serotonin Uptake Inhibitors;Antidepressive Agents, Second-Generation |
| DB00477 | inhibitor | Chlorpromazine | Antiemetics;Antipsychotics;Dopamine Antagonists;Phenothiazines;Antipsychotic Agents |
| DB00501 | inhibitor | Cimetidine | Anti-Ulcer Agents;Analgesics;Enzyme Inhibitors;Adjuvants;Histamine Antagonists;Histamine H2 Antagonists |
| DB00503 | inhibitor | Kaletra | Anti-HIV Agents;HIV Protease Inhibitors |
| DB00514 | substrate | Tussin Cough Medicine Dm Antitussive Expectorant Decongestant | Analgesics, Opioid;Antitussive Agents;Excitatory Amino Acid Antagonists |
| DB00526 | substrate | Oxaliplatin | Antineoplastic Agents |
| DB00532 | - | Mephenytoin | Anticonvulsants |
| DB00540 | inhibitor | Nortriptyline | Antidepressants;Adrenergic Uptake Inhibitors;Antidepressive Agents, Tricyclic;Norepinephrine-Reuptake Inhibitors |
| DB00549 | inhibitor | Zafirlukast | Anti-Asthmatic Agents;Leukotriene Antagonists |
| DB00586 | inhibitor | Diclofenac | Cyclooxygenase Inhibitors;Nonsteroidal Anti-inflammatory Agents (NSAIAs) |
| DB00593 | substrate | Ethosuximide | Anticonvulsants;Succinimides |
| DB00599 | inhibitor | Thiotal 5g | Hypnotics and Sedatives;Anticonvulsants;GABA Modulators;Anesthetics, Intravenous |
| DB00617 | substrate | Paramethadione | Anticonvulsants |
| DB00622 | substrate | Nicardipine | Antihypertensive Agents;Vasodilator Agents;Antiarrhythmic Agents;Calcium Channel Blockers;Dihydropyridines |
| DB00623 | inhibitor | Fluphenazine | Antipsychotics;Dopamine Antagonists;Phenothiazines;Antipsychotic Agents |
| DB00636 | inducer | Clofibrate | Anticholesteremic Agents;Antilipemic Agents |
| DB00655 | substrate | Holis 98 | Antineoplastic Agents;Estrogens;Osteoporosis Prophylactic;Anti-menopausal Agents |
| DB00675 | substrate | Tamoxifen | Antineoplastic Agents, Hormonal;Selective Estrogen Receptor Modulators;Estrogen Antagonists;Bone Density Conservation Agents |
| DB00679 | inhibitor | Thioridazine | Antipsychotics;Dopamine Antagonists;Phenothiazines;Antipsychotic Agents |
| DB00690 | inhibitor | Flurazepam | Anti-anxiety Agents;Hypnotics and Sedatives;GABA Modulators |
| DB00698 | - | Nitrofurantoin | Anti-Infectives;Anti-Infective Agents, Urinary |
| DB00703 | inhibitor | Methazolamide | Diuretics;Carbonic Anhydrase Inhibitors |
| DB00748 | substrate | Carbinoxamine | Antihistamines |
| DB00752 | inhibitor | Tranylcypromine | Antidepressants;Anti-anxiety Agents;Antidepressive Agents;Monoamine Oxidase Inhibitors |
| DB00753 | substrate | Isoflurane | Anesthetics, Inhalation;General Anesthetics;Anesthetics |
| DB00763 | inhibitor | Methimazole | Antithyroid Agents |
| DB00773 | substrate | Etoposide | Nucleic Acid Synthesis Inhibitors;Antineoplastic Agents, Phytogenic |
| DB00780 | - | Phenelzine | Antidepressants;Antidepressive Agents;Monoamine Oxidase Inhibitors |
| DB00818 | inhibitor | Propofol | Free Radical Scavengers;Hypnotics and Sedatives;Antiemetics;Anticonvulsants;Anesthetics, Intravenous |
| DB00822 | inhibitor | Disulfiram | Enzyme Inhibitors;Alcohol Deterrents |
| DB00835 | substrate | Tantapp Elixir | Anti-Allergic Agents;Histamine H1 Antagonists |
| DB00851 | substrate | Dacarbazine | Antineoplastic Agents;Antineoplastic Agents, Alkylating |
| DB00882 | inhibitor | Clomifene | Selective Estrogen Receptor Modulators;Estrogen Antagonists;Fertility Agents, Female |
| DB00883 | inhibitor | BiDil | Vasodilator Agents;Nitrates and Nitrites;Nitric Oxide Donors |
| DB00898 | inducer | Ethanol | Anti-Infective Agents, Local;Solvents;Central Nervous System Depressants;Disinfectants |
| DB00904 | substrate | Ondansetron | Anti-anxiety Agents;Antiemetics;Antipsychotics;Serotonin Antagonists;Antipruritics;Antipsychotic Agents |
| DB00908 | substrate | Quinidine | Enzyme Inhibitors;Antiarrhythmic Agents;Antimalarials;Muscarinic Antagonists;Adrenergic alpha-Antagonists;Anti-Arrhythmia Agents |
| DB00949 | substrate | Felbamate | Anticonvulsants;Neuroprotective Agents;Antiepileptic Agents |
| DB00951 | inducer | Rifater | Antitubercular Agents;Fatty Acid Synthesis Inhibitors |
| DB00969 | inhibitor | Alosetron | Serotonin Antagonists;Gastrointestinal Agents |
| DB00972 | inhibitor | Azelastine | Lipoxygenase Inhibitors;Platelet Aggregation Inhibitors;Bronchodilator Agents;Anti-Allergic Agents;Histamine H1 Antagonists;Histamine H1 Antagonists, Non-Sedating |
| DB01007 | inhibitor | GyneCure Vaginal Ovules Tandempak | Antifungal Agents |
| DB01011 | inhibitor | Metyrapone | Antimetabolites;Enzyme Inhibitors |
| DB01028 | substrate | Methoxyflurane | Anesthetics, Inhalation |
| DB01037 | inhibitor | Selegiline | Central Nervous System Agents;Antiparkinson Agents;Antidyskinetics;Neuroprotective Agents;Monoamine Oxidase Inhibitors;Dopaminergics |
| DB01041 | substrate | Thalidomide | Immunosuppressive Agents;Leprostatic Agents;Teratogens;Angiogenesis Inhibitors |
| DB01045 | inducer | Rifater | Enzyme Inhibitors;Antituberculosis Agents;Nucleic Acid Synthesis Inhibitors;Leprostatic Agents;Antibiotics;Antibiotics, Antitubercular |
| DB01079 | inhibitor | Tegaserod | Gastrointestinal Agents;Serotonin Agonists |
| DB01085 | substrate | Timpilo 4 | Muscarinic Agonists;Miotics;Cholinergic Agents |
| DB01100 | inhibitor | Pimozide | Dopamine Antagonists;Antipsychotic Agents;Anti-Dyskinesia Agents |
| DB01110 | inhibitor | Miconazole | Antifungal Agents |
| DB01115 | inhibitor | Nifedipine | Vasodilator Agents;Calcium Channel Blockers;Tocolytic Agents;Dihydropyridines |
| DB01124 | - | Tolbutamide | Hypoglycemic Agents;Sulfonylureas |
| DB01127 | inhibitor | Econazole | Antifungal Agents |
| DB01131 | substrate | Proguanil | Antimetabolites;Antimalarials |
| DB01136 | substrate | Carvedilol | Antihypertensive Agents;Adrenergic Agents;Adrenergic beta-Antagonists;Vasodilator Agents;Adrenergic alpha-Antagonists |
| DB01151 | inhibitor | Desipramine | Antidepressants;Adrenergic Uptake Inhibitors;Enzyme Inhibitors;Antidepressive Agents, Tricyclic;Norepinephrine-Reuptake Inhibitors |
| DB01156 | substrate | Bupropion | Dopamine Uptake Inhibitors;Antidepressive Agents;Antidepressive Agents, Second-Generation |
| DB01159 | substrate | Halothane | Anesthetics, Inhalation;General Anesthetics;Anesthetics |
| DB01167 | inhibitor | Itraconazole | Antifungals;Antiprotozoals;Antifungal Agents;Antiprotozoal Agents |
| DB01173 | - | Orphenadrine | Skeletal Muscle Relaxants;Antiparkinson Agents;Antidyskinetics;Muscarinic Antagonists;Muscle Relaxants, Central;Parasympatholytics |
| DB01174 | inducer | Phenobarbital | Hypnotics and Sedatives;Anticonvulsants;GABA Modulators;Excitatory Amino Acid Antagonists |
| DB01191 | inhibitor | Dexfenfluramine | Appetite Depressants;Serotonin Agonists;Serotonin reuptake inhibitor;Antiobesity Agents |
| DB01198 | substrate | Zopiclone | Hypnotics and Sedatives |
| DB01204 | substrate | Mitoxantrone | Antineoplastic Agents;Analgesics |
| DB01213 | inhibitor | Fomepizole | Antidotes |
| DB01223 | substrate | Quiex-Pred Sus | Phosphodiesterase Inhibitors;Bronchodilator Agents;Cardiotonic Agents;Respiratory Smooth Muscle Relaxants |
| DB01234 | inducer | Tresaderm Dermatologic Solution | Anti-inflammatory Agents;Adrenergic Agents;Antiemetics;Antineoplastic Agents, Hormonal;Glucocorticoids |
| DB01236 | substrate | Sevoflurane | Platelet Aggregation Inhibitors;Anesthetics, Inhalation |
| DB01296 | substrate | Glucosamine | |
| DB01355 | - | Hexobarbital | Hypnotics and Sedatives;GABA Modulators;Barbiturates;Adjuvants |
| DB01394 | inducer | Sucurnix HP | Gout Suppressants;Tubulin Modulators |
| DB01403 | inhibitor | Methotrimeprazine | Dopamine Antagonists;Analgesics, Non-Narcotic;Antipsychotic Agents |
| DB01412 | substrate | Theobromine | Vasodilator Agents;Bronchodilator Agents |
| DB01435 | substrate | Formule L2 | |
| DB01558 | inhibitor | Bromazepam | Anti-anxiety Agents;Hypnotics and Sedatives;Benzodiazepines;GABA Modulators |
| DB01586 | inducer | Ursodeoxycholic acid | Cholagogues and Choleretics |
| DB01628 | inhibitor | Etoricoxib | Cyclooxygenase Inhibitors |
| DB02701 | inhibitor | Nicotinamide | Vitamin B Complex |
| DB03783 | substrate | Phenacetin | Analgesics;Analgesics, Non-Narcotic |
| DB04077 | inducer | Glycerol | Solvents;Cryoprotective Agents |
| DB04794 | inhibitor | Bifonazole | Antifungal Agents |
| DB05109 | substrate | Trabectedin | Antineoplastic Agents, Alkylating |
| DB06689 | substrate | Ethanolamine Oleate | Sclerosing Solutions |
| DB06712 | substrate | Nilvadipine | Antihypertensive Agents;Calcium Channel Blockers |
| DB06716 | inhibitor | Fospropofol | Hypnotics and Sedatives;Anesthetics, Intravenous |
| DB06728 | substrate | Aniline |
| No data |
| No data |