AutismKB 2.0

Annotation Detail for VPS13B


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Basic Information Top
Gene Symbol:VPS13B ( CHS1,COH1,DKFZp313I0811,KIAA0532 )
Gene Full Name: vacuolar protein sorting 13 homolog B (yeast)
Band: 8q22.2
Quick LinksEntrez ID:157680; OMIM: 607817; Uniprot ID:VP13B_HUMAN; ENSEMBL ID: ENSG00000132549; HGNC ID: 2183
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of VPS13B mRNAaffects expression 21346803
D000638 Amiodarone Amiodarone results in increased expression of VPS13B mRNAincreases expression 19774075
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of VPS13B mRNAdecreases expression 20106945
20064835
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of VPS13B mRNAaffects expression 20382639
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of VPS13B mRNAdecreases expression 20018196
D014501 Uranium Uranium affects the expression of VPS13B mRNAaffects expression 15672453
C005460 uranyl acetate uranyl acetate affects the expression of VPS13B mRNAaffects expression 15672453
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0420127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 2.826695378
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.4919183758
MESH:D001145 Arrhythmias, Cardiac Amiodarone 4.1120041841 18218290 18057881
MESH:D001281 Atrial Fibrillation Amiodarone 4.1318651412 19698954
MESH:D001778 Blood Coagulation Disorders Amiodarone 4.2219483382
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.0020146248 17474063
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 1.7816705839
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1220419170
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.9815710769 19225199
MESH:D002341 Carotid Artery Thrombosis Amiodarone 5.5518974383
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 7.356135515
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.3520889678
MESH:C536438 Cohen syndrome marker/mechanism 15154116 12730828 17990063
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.4418551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 4.2618551238 21346803
MESH:D056486 Drug-Induced Liver Injury Amiodarone 4.2618218290 15265979
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.5720426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.5716530937
MESH:D005234 Fatty Liver Amiodarone 3.8414986274
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8020471113
MESH:D006529 Hepatomegaly Amiodarone 4.1615265979
MESH:D006937 Hypercholesterolemia Amiodarone 4.209751232 8137927
MESH:D007037 Hypothyroidism Amiodarone 4.9317991464 18020914
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 3.2416705839
MESH:D008064 Lipidoses Amiodarone 3.7315342952 17567588
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 4.827678174
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 4.8220195826 21137059
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.722876784 2876786 6135515
MESH:D008133 Long QT Syndrome Amiodarone 3.8211989578 15350150 17391786
MESH:D008171 Lung Diseases Amiodarone 3.5712587719
MESH:D017563 Lung Diseases, Interstitial Amiodarone 5.0018516814
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 1.5720464547 20064080 18569708 18816296 18520028 6695378 20135361 17053015 20869020
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.4316381670
MESH:D009181 Mycoses Amiodarone 5.4212754197 17974566
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.3218551238 7678174
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3011141357
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.7416049721
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9217292933
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.9512832656 12490602 11597910
MESH:D012640 Seizures 2,6-dinitrotoluene 2.7418551238
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 5.5518724381
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.4910029692 19755658
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.562093021 20155912
MESH:D013276 Stomach Ulcer Amiodarone 3.6418087811
MESH:D013610 Tachycardia Amiodarone 4.6711238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.5719225199
MESH:D013959 Thyroid Diseases Amiodarone 5.2819731979
MESH:D013971 Thyrotoxicosis Amiodarone 5.2818020914 19584973
MESH:D016171 Torsades de Pointes Amiodarone 4.6517467628 11989578
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 5.3216049721
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 5.3217053015
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.7810091137
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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