AutismKB 2.0

Annotation Detail for MOSPD2


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Basic Information Top
Gene Symbol:MOSPD2 ( DKFZp686C1553,MGC26706 )
Gene Full Name: motile sperm domain containing 2
Band: Xp22.2
Quick LinksEntrez ID:158747; OMIM: NA; Uniprot ID:MSPD2_HUMAN; ENSEMBL ID: ENSG00000130150; HGNC ID: 28381
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
D001151 Arsenic Arsenic results in decreased expression of MOSPD2 mRNAdecreases expression 19654921
D003010 Clorgyline Clorgyline results in increased expression of MOSPD2 mRNAincreases expression 19691856
C018021 cobaltous chloride cobaltous chloride results in decreased expression of MOSPD2 mRNAdecreases expression 20105288
C006253 pirinixic acid pirinixic acid results in decreased expression of MOSPD2 mRNAdecreases expression 18445702
C006253 pirinixic acid pirinixic acid results in increased expression of MOSPD2 mRNAincreases expression 18301758
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055371 Acute Lung Injury pirinixic acid 3.5818653653
MESH:D018248 Adenoma, Liver Cell pirinixic acid 4.1116434500
MESH:D018246 Adrenocortical Adenoma Arsenic 5.9417306315
MESH:D020261 Arsenic Poisoning Arsenic 2.9516835338 16251483 18414634 12569548
MESH:D050197 Atherosclerosis Arsenic 3.4612928151 19371607
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.5719483382
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.7817687452 15504454
MESH:D006528 Carcinoma, Hepatocellular Arsenic 2.3216507464 17306315
MESH:D002294 Carcinoma, Squamous Cell Arsenic 2.7715504454 18922899 17687452
MESH:D002295 Carcinoma, Transitional Cell Arsenic 4.4718640142
MESH:D002318 Cardiovascular Diseases Arsenic 3.7115738583 19152805 17938729
MESH:D002340 Carotid Artery Diseases Arsenic 4.6818022660 16973168
MESH:D002779 Cholestasis pirinixic acid 3.1219176532
MESH:D017449 Dermatitis, Allergic Contact cobaltous chloride 4.5816823706 15059100 11298694
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5718249437
MESH:D004487 Edema pirinixic acid 2.9012083418
MESH:D005234 Fatty Liver pirinixic acid 3.1920131406 19236843
MESH:D005534 Foot Diseases Arsenic 6.286392382
MESH:D006333 Heart Failure pirinixic acid 2.7620558911
MESH:D006529 Hepatomegaly pirinixic acid 3.5519772884 16221962 19176532 18467677
MESH:D006943 Hyperglycemia pirinixic acid 3.5820558911
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.8517050553
MESH:D006973 Hypertension Arsenic 2.9916076760 11953799 9931084
MESH:D006987 Hypesthesia Arsenic 6.2816093927
MESH:D007333 Insulin Resistance pirinixic acid 2.8716306350
MESH:D007642 Keratosis Arsenic 5.6216930632 12749816
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 3.7917339181
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008107 Liver Diseases Arsenic 2.6111134558
MESH:D008113 Liver Neoplasms Arsenic 5.0116368122
MESH:D008113 Liver Neoplasms pirinixic acid 5.0120007298 16377806 15890375
MESH:D008175 Lung Neoplasms Arsenic 2.2117976673 17306315 19168569
MESH:D009135 Muscular Diseases pirinixic acid 4.0716239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.2719151258
MESH:D017202 Myocardial Ischemia Arsenic 4.3115371236
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.2516411023
MESH:D009369 Neoplasms pirinixic acid 2.1117405874
MESH:D009436 Neural Tube Defects Arsenic 3.6916620997
MESH:D020078 Neurogenic Inflammation Arsenic 4.8417056641
MESH:D009765 Obesity pirinixic acid 1.8820558911
MESH:D010051 Ovarian Neoplasms Arsenic 2.8417306315
MESH:D010523 Peripheral Nervous System Diseases Arsenic 4.6816093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 5.6216905509 6392382 15371236
MESH:D011471 Prostatic Neoplasms Arsenic 3.7016140617
MESH:D011471 Prostatic Neoplasms Clorgyline 3.7019691856
MESH:D011507 Proteinuria Arsenic 4.4721343184
MESH:D015427 Reperfusion Injury pirinixic acid 2.5519058328
MESH:D012871 Skin Diseases Arsenic 2.8217453740 19834688 6392382 16702368 15952646 18709164 16353154 17050553 17548696 17938729 16759981
MESH:D012878 Skin Neoplasms Arsenic 3.1617976673 19538983 17029826 15504454 16251483 17050553
MESH:D001749 Urinary Bladder Neoplasms Arsenic 2.9417976673 15987713 19322015 19429237 11144890 18640142 17306315
MESH:D014652 Vascular Diseases Arsenic 5.3717056641
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018