AutismKB 2.0

Annotation Detail for CYP24A1


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Basic Information Top
Gene Symbol:CYP24A1 ( CP24,CYP24,MGC126273,MGC126274,P450-CC24 )
Gene Full Name: cytochrome P450, family 24, subfamily A, polypeptide 1
Band: 20q13.2
Quick LinksEntrez ID:1591; OMIM: 126065; Uniprot ID:CP24A_HUMAN; ENSEMBL ID: ENSG00000019186; HGNC ID: 2602
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Hormone biosynthesis
Metabolism of vitamins and cofactors
Metabolism of lipids and lipoproteins
Biological oxidations
No data
Pathway IDPathway Name
P04396Vitamin D metabolism and pathway
Pathway IDPathway Name
500600Vitamin D (calciferol) metabolism
500202Vitamins
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1904Diabetes mellitus
1934Cancer
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C097949 1,25-dihydroxyvitamin D U 0126 inhibits the reaction [1,25-dihydroxyvitamin D results in increased expression of CYP24A1 mRNA]decreases reaction|increases expression 15331595
C097949 1,25-dihydroxyvitamin D U 0126 promotes the reaction [1,25-dihydroxyvitamin D results in increased expression of CYP24A1 mRNA]increases expression|increases reaction 15331595
C097949 1,25-dihydroxyvitamin D CYP24A1 protein results in increased degradation of 1,25-dihydroxyvitamin Dincreases degradation 15781002
C482452 1-(4-(4-(4-((4-(2,4-difluorophenyl)-4-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-2-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-3-(1-methylethyl)-2-imidazolidinone 1-(4-(4-(4-((4-(2,4-difluorophenyl)-4-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-2-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-3-(1-methylethyl)-2-imidazolidinone results in decreased activity of CYP24A1 proteindecreases activity 15328084
C482452 1-(4-(4-(4-((4-(2,4-difluorophenyl)-4-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-2-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-3-(1-methylethyl)-2-imidazolidinone 1-(4-(4-(4-((4-(2,4-difluorophenyl)-4-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-2-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-3-(1-methylethyl)-2-imidazolidinone results in decreased activity of CYP24A1 proteindecreases activity 15328084
C065250 4-hydroxy-equilenin 4-hydroxy-equilenin results in decreased expression of CYP24A1 mRNAdecreases expression 15135645
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of CYP24A1 proteinaffects expression 20106945
D013196 Dihydrotestosterone Dihydrotestosterone inhibits the reaction [Calcifediol results in increased expression of CYP24A1 mRNA]decreases reaction|increases expression 16524720
D013196 Dihydrotestosterone Dihydrotestosterone inhibits the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]decreases reaction|increases expression 15538745
C011512 alpha-naphthoflavone alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [Calcitriol promotes the reaction [VDR protein binds to CYP24A1 promoter]]]affects binding|decreases reaction|increases reaction 19244278
C011512 alpha-naphthoflavone alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]]decreases reaction|increases expression|increases reaction 19244278
C011512 alpha-naphthoflavone alpha-naphthoflavone inhibits the reaction [Cycloheximide promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]]decreases reaction|increases expression|increases reaction 19244278
C061133 Am 80 Am 80 inhibits the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]decreases reaction|increases expression 16289102
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CYP24A1 mRNAaffects expression 16483693
C526219 apple polyphenol extract apple polyphenol extract results in increased expression of CYP24A1 mRNAincreases expression 18351577
D016718 Arachidonic Acid Arachidonic Acid results in decreased expression of CYP24A1 mRNAdecreases expression 16623957
C015001 arsenite arsenite results in increased methylation of CYP24A1 promoterincreases methylation 19716837
D001564 Benzo(a)pyrene alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [Calcitriol promotes the reaction [VDR protein binds to CYP24A1 promoter]]]affects binding|decreases reaction|increases reaction 19244278
D001564 Benzo(a)pyrene alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]]decreases reaction|increases expression|increases reaction 19244278
D001564 Benzo(a)pyrene Benzo(a)pyrene inhibits the reaction [Calcitriol promotes the reaction [RXRA protein binds to CYP24A1 promoter]]affects binding|decreases reaction|increases reaction 19244278
D001564 Benzo(a)pyrene Benzo(a)pyrene inhibits the reaction [Calcitriol promotes the reaction [VDR protein binds to CYP24A1 promoter]]affects binding|decreases reaction|increases reaction 19244278
D001564 Benzo(a)pyrene Benzo(a)pyrene promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]increases expression|increases reaction 19244278
D001564 Benzo(a)pyrene Benzo(a)pyrene promotes the reaction [CYP24A1 protein results in increased degradation of Calcitriol]increases degradation|increases reaction 19244278
D001564 Benzo(a)pyrene Benzo(a)pyrene promotes the reaction [Lithocholic Acid results in increased expression of CYP24A1 mRNA]increases expression|increases reaction 19244278
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of CYP24A1 mRNAincreases expression 20106945
C402892 BMS453 BMS453 inhibits the reaction [Tretinoin inhibits the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]]decreases reaction|increases expression 16289102
D002118 Calcium Calcium affects the expression of CYP24A1 mRNAaffects expression 15913539
D002118 Calcium [Calcium co-treated with Calcitriol] affects the expression of CYP24A1 mRNAaffects cotreatment|affects expression 15913539
D002136 Calcium, Dietary Calcium, Dietary affects the expression of CYP24A1 mRNAaffects expression 15905206
C505748 CD4528 CD4528 results in increased expression of CYP24A1 mRNAincreases expression 15860548
D003513 Cycloheximide alpha-naphthoflavone inhibits the reaction [Cycloheximide promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]]decreases reaction|increases expression|increases reaction 19244278
D003513 Cycloheximide Cycloheximide inhibits the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]decreases reaction|increases expression 19244278
D016572 Cyclosporine Cyclosporine results in increased expression of CYP24A1 mRNAincreases expression 20106945
D003907 Dexamethasone Dexamethasone affects the activity of CYP24A1 proteinaffects activity 10694374
D003907 Dexamethasone Dexamethasone affects the expression of CYP24A1 mRNAaffects expression 10694374
D003907 Dexamethasone Dexamethasone results in increased expression of CYP24A1 mRNAincreases expression 15630458
D002117 Calcitriol Calcitriol results in increased expression of CYP24A1 mRNAincreases expression 15992766
D002117 Calcitriol alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene inhibits the reaction [Calcitriol promotes the reaction [VDR protein binds to CYP24A1 promoter]]]affects binding|decreases reaction|increases reaction 19244278
D002117 Calcitriol alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]]decreases reaction|increases expression|increases reaction 19244278
D002117 Calcitriol alpha-naphthoflavone inhibits the reaction [Cycloheximide promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]]decreases reaction|increases expression|increases reaction 19244278
D002117 Calcitriol Am 80 inhibits the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]decreases reaction|increases expression 16289102
D002117 Calcitriol Benzo(a)pyrene inhibits the reaction [Calcitriol promotes the reaction [RXRA protein binds to CYP24A1 promoter]]affects binding|decreases reaction|increases reaction 19244278
D002117 Calcitriol Benzo(a)pyrene inhibits the reaction [Calcitriol promotes the reaction [VDR protein binds to CYP24A1 promoter]]affects binding|decreases reaction|increases reaction 19244278
D002117 Calcitriol Benzo(a)pyrene promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]increases expression|increases reaction 19244278
D002117 Calcitriol Benzo(a)pyrene promotes the reaction [CYP24A1 protein results in increased degradation of Calcitriol]increases degradation|increases reaction 19244278
D002117 Calcitriol BMS453 inhibits the reaction [Tretinoin inhibits the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]]decreases reaction|increases expression 16289102
D002117 Calcitriol Calcitriol promotes the reaction [RXRA protein binds to CYP24A1 promoter]affects binding|increases reaction 19244278
D002117 Calcitriol Calcitriol promotes the reaction [VDR protein binds to CYP24A1 promoter]affects binding|increases reaction 15919092
19244278
D002117 Calcitriol Calcitriol promotes the reaction [[VDR protein binds to MED1 protein] which binds to CYP24A1 promoter]affects binding|increases reaction 15919092
D002117 Calcitriol Calcitriol promotes the reaction [[VDR protein binds to NCOA3 protein] which binds to CYP24A1 promoter]affects binding|increases reaction 15919092
D002117 Calcitriol Calcitriol promotes the reaction [[VDR protein binds to RXRA protein] which binds to CYP24A1 promoter]affects binding|increases reaction 15919092
D002117 Calcitriol Calcitriol results in increased activity of CYP24A1 proteinincreases activity 15955619
D002117 Calcitriol Calcitriol results in increased expression of CYP24A1increases expression 16039846
D002117 Calcitriol Calcitriol results in increased expression of CYP24A1 mRNAincreases expression 15538745
16061850
16289102
15992766
16002434
14996990
15890193
15919092
15955619
19244278
D002117 Calcitriol Cycloheximide inhibits the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]decreases reaction|increases expression 19244278
D002117 Calcitriol CYP24A1 protein results in increased degradation of Calcitriolincreases degradation 15955619
D002117 Calcitriol CYP24A1 protein results in increased metabolism of and results in decreased susceptibility to Calcitrioldecreases response to substance|increases metabolic processing 15867263
D002117 Calcitriol Dihydrotestosterone inhibits the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]decreases reaction|increases expression 15538745
D002117 Calcitriol Genistein inhibits the reaction [Calcitriol results in increased activity of CYP24A1 protein]decreases reaction|increases activity 15955619
D002117 Calcitriol Genistein inhibits the reaction [CYP24A1 protein results in increased degradation of Calcitriol]decreases reaction|increases degradation 15955619
D002117 Calcitriol Genistein promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]increases expression|increases reaction 15955619
D002117 Calcitriol Methylcholanthrene promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]increases expression|increases reaction 19244278
D002117 Calcitriol Tetrachlorodibenzodioxin promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]increases expression|increases reaction 19244278
D002117 Calcitriol Tretinoin inhibits the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]decreases reaction|increases expression 16289102
D002117 Calcitriol Calcitriol affects the expression of and affects the activity of CYP24A1 proteinaffects activity|affects expression 17244627
D002117 Calcitriol Calcitriol affects the expression of CYP24A1 mRNAaffects expression 17244627
D002117 Calcitriol Calcitriol affects the expression of CYP24A1 proteinaffects expression 11796525
D002117 Calcitriol Calcitriol promotes the reaction [CBP protein binds to CYP24A1 promoter]affects binding|increases reaction 15647825
D002117 Calcitriol Calcitriol promotes the reaction [EP300 protein binds to CYP24A1 promoter]affects binding|increases reaction 15647825
D002117 Calcitriol Calcitriol promotes the reaction [MED1 protein binds to CYP24A1 promoter]affects binding|increases reaction 15647825
D002117 Calcitriol Calcitriol promotes the reaction [NCOA1 protein binds to CYP24A1 promoter]affects binding|increases reaction 15647825
D002117 Calcitriol Calcitriol promotes the reaction [NCOA2 protein binds to CYP24A1 promoter]affects binding|increases reaction 15647825
D002117 Calcitriol Calcitriol promotes the reaction [NCOA3 protein binds to CYP24A1 promoter]affects binding|increases reaction 15647825
D002117 Calcitriol Calcitriol promotes the reaction [RXRA protein binds to CYP24A1 promoter]affects binding|increases reaction 15647825
D002117 Calcitriol Calcitriol promotes the reaction [VDR protein binds to CYP24A1 promoter]affects binding|increases reaction 15647825
D002117 Calcitriol Calcitriol results in increased activity of CYP24A1 proteinincreases activity 10694374
D002117 Calcitriol Calcitriol results in increased expression of CYP24A1 mRNAincreases expression 10694374
D002117 Calcitriol CYP24A1 protein results in increased susceptibility to Calcitriolincreases response to substance 17244627
D002117 Calcitriol Calcitriol results in increased activity of CYP24A1 proteinincreases activity 16483768
D002117 Calcitriol [Calcium co-treated with Calcitriol] affects the expression of CYP24A1 mRNAaffects cotreatment|affects expression 15913539
D002117 Calcitriol CYP24A1 protein affects the abundance of Calcitriolaffects abundance 12846736
D002117 Calcitriol [Ketoconazole co-treated with Calcitriol] results in increased expression of CYP24A1 mRNAaffects cotreatment|increases expression 16483768
D002117 Calcitriol Ketoconazole inhibits the reaction [Calcitriol results in increased activity of CYP24A1 protein]decreases reaction|increases activity 16483768
D002117 Calcitriol Calcitriol promotes the reaction [[VDR protein binds to RXRA protein] which binds to CYP24A1 promoter]affects binding|increases reaction 15992766
D004958 Estradiol Estradiol results in increased expression of CYP24A1 mRNAincreases expression 20106945
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CYP24A1 mRNAaffects cotreatment|increases expression 17942748
D005480 Flurbiprofen Flurbiprofen results in decreased expression of CYP24A1 mRNAdecreases expression 16949054
C056507 gemcitabine gemcitabine results in decreased expression of CYP24A1 mRNAdecreases expression 17039268
D019833 Genistein Genistein inhibits the reaction [Calcitriol results in increased activity of CYP24A1 protein]decreases reaction|increases activity 15955619
D019833 Genistein Genistein inhibits the reaction [CYP24A1 protein results in increased degradation of Calcitriol]decreases reaction|increases degradation 15955619
D019833 Genistein Genistein promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]increases expression|increases reaction 15955619
D019833 Genistein Genistein results in decreased activity of CYP24A1 proteindecreases activity 15955619
D002112 Calcifediol Calcifediol results in increased expression of CYP24A1 mRNAincreases expression 16289102
16524720
D002112 Calcifediol Dihydrotestosterone inhibits the reaction [Calcifediol results in increased expression of CYP24A1 mRNA]decreases reaction|increases expression 16524720
D002112 Calcifediol Tretinoin inhibits the reaction [Calcifediol results in increased expression of CYP24A1 mRNA]decreases reaction|increases expression 16289102
C001654 hyperforin hyperforin results in increased expression of CYP24A1 mRNAincreases expression 15630458
D017964 Itraconazole Itraconazole results in decreased activity of CYP24A1 proteindecreases activity 15328084
D017964 Itraconazole Itraconazole results in decreased activity of CYP24A1 proteindecreases activity 15328084
D007654 Ketoconazole [Ketoconazole co-treated with Calcitriol] results in increased expression of CYP24A1 mRNAaffects cotreatment|increases expression 16483768
D007654 Ketoconazole Ketoconazole inhibits the reaction [Calcitriol results in increased activity of CYP24A1 protein]decreases reaction|increases activity 16483768
D007654 Ketoconazole Ketoconazole results in decreased activity of CYP24A1 proteindecreases activity 16483768
D008095 Lithocholic Acid Benzo(a)pyrene promotes the reaction [Lithocholic Acid results in increased expression of CYP24A1 mRNA]increases expression|increases reaction 19244278
D008095 Lithocholic Acid Lithocholic Acid results in increased expression of CYP24A1 mRNAincreases expression 19244278
D008095 Lithocholic Acid Lithocholic Acid promotes the reaction [[VDR protein binds to RXRA protein] which binds to CYP24A1 promoter]affects binding|increases reaction 15992766
D008748 Methylcholanthrene Methylcholanthrene promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]increases expression|increases reaction 19244278
D008767 Methylmercury Compounds Methylmercury Compounds results in decreased expression of CYP24A1 mRNAdecreases expression 16966085
C406082 monomethylarsonous acid monomethylarsonous acid results in increased methylation of CYP24A1 promoterincreases methylation 19716837
C084656 paricalcitol [Phosphorus co-treated with paricalcitol] results in increased expression of CYP24A1 mRNAaffects cotreatment|increases expression 17715259
C084656 paricalcitol [Phosphorus co-treated with paricalcitol] results in increased expression of CYP24A1 mRNAaffects cotreatment|increases expression 17715259
D010758 Phosphorus [Phosphorus co-treated with paricalcitol] results in increased expression of CYP24A1 mRNAaffects cotreatment|increases expression 17715259
D010758 Phosphorus Phosphorus affects the reaction [FGF23 protein results in increased expression of CYP24A1 mRNA]affects reaction|increases expression 17699549
D010758 Phosphorus [Phosphorus co-treated with paricalcitol] results in increased expression of CYP24A1 mRNAaffects cotreatment|increases expression 17715259
D016226 Phosphorus, Dietary Phosphorus, Dietary results in increased expression of CYP24A1 mRNAincreases expression 16123154
D016226 Phosphorus, Dietary Phosphorus, Dietary affects the expression of CYP24A1 mRNAaffects expression 15166007
D016226 Phosphorus, Dietary Phosphorus, Dietary affects the expression of CYP24A1 mRNAaffects expression 15877868
D010936 Plant Extracts Plant Extracts results in increased expression of CYP24A1 mRNAincreases expression 18351577
D011285 Pregnenolone Carbonitrile Pregnenolone Carbonitrile results in increased expression of CYP24A1 mRNAincreases expression 15630458
C045950 propiconazole propiconazole results in increased expression of CYP24A1 mRNAincreases expression 16730040
D020849 Raloxifene [Raloxifene co-treated with ESR2 protein] results in decreased expression of CYP24A1 mRNAaffects cotreatment|decreases expression 19059307
D012293 Rifampin Rifampin promotes the reaction [NR1I2 protein binds to CYP24A1 promoter]affects binding|increases reaction 15630458
D012293 Rifampin Rifampin results in increased activity of CYP24A1 proteinincreases activity 15630458
D012293 Rifampin Rifampin results in increased expression of CYP24A1 mRNAincreases expression 15630458
D013629 Tamoxifen [Tamoxifen co-treated with ESR2 protein] results in decreased expression of CYP24A1 mRNAaffects cotreatment|decreases expression 19059307
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]increases expression|increases reaction 19244278
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of CYP24A1 mRNAincreases expression 20106945
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CYP24A1 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of CYP24A1 mRNAincreases expression 16267337
D014212 Tretinoin BMS453 inhibits the reaction [Tretinoin inhibits the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]]decreases reaction|increases expression 16289102
D014212 Tretinoin Tretinoin inhibits the reaction [Calcifediol results in increased expression of CYP24A1 mRNA]decreases reaction|increases expression 16289102
D014212 Tretinoin Tretinoin inhibits the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]decreases reaction|increases expression 16289102
D014212 Tretinoin Tretinoin results in increased expression of CYP24A1 mRNAincreases expression 16249480
C032910 triadimefon triadimefon results in increased expression of CYP24A1 mRNAincreases expression 16730040
C113580 U 0126 U 0126 inhibits the reaction [1,25-dihydroxyvitamin D results in increased expression of CYP24A1 mRNA]decreases reaction|increases expression 15331595
C113580 U 0126 U 0126 promotes the reaction [1,25-dihydroxyvitamin D results in increased expression of CYP24A1 mRNA]increases expression|increases reaction 15331595
D014501 Uranium Uranium results in decreased expression of CYP24A1 mRNAdecreases expression 17118558
D014807 Vitamin D CYP24A1 protein affects the metabolism of and results in decreased activity of Vitamin D metaboliteaffects metabolic processing|decreases activity 15630458
D002762 Cholecalciferol Cholecalciferol results in increased expression of CYP24A1 mRNAincreases expression 16207822
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.0214745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.3414514962 15322242 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.0418287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.4117505938
MESH:D000168 Acrocephalosyndactylia U 0126 4.9717694057
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 8.8220127859 20464547
MESH:D000230 Adenocarcinoma Estradiol 8.8211473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 8.8214692618
MESH:D000230 Adenocarcinoma Genistein 8.8211473722
MESH:D000236 Adenoma Benzo(a)pyrene 5.816695378
MESH:D000236 Adenoma Methylcholanthrene 5.816695378 10545420
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 2.8616835633
MESH:D011125 Adenomatous Polyposis Coli Flurbiprofen 4.6210680582
MESH:D000419 Albuminuria Raloxifene 4.1017451421 17308373
MESH:D000505 Alopecia Tretinoin 3.2015955085
MESH:D000544 Alzheimer Disease Plant Extracts 4.1016962711
MESH:D000544 Alzheimer Disease Raloxifene 4.1015800139
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.5011748828
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.5719183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 2.9611256880
MESH:D001169 Arthritis, Experimental Dexamethasone 14.8117659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 14.8115885639
MESH:D001169 Arthritis, Experimental Plant Extracts 14.8114686799
MESH:D001169 Arthritis, Experimental Tretinoin 14.8116412693
MESH:D001172 Arthritis, Rheumatoid Am 80 4.6016819260
MESH:D001172 Arthritis, Rheumatoid Tretinoin 4.6016292516
MESH:D001249 Asthma Tretinoin 2.1716456186
MESH:D050197 Atherosclerosis Am 80 6.2816484594
MESH:D050197 Atherosclerosis Methylcholanthrene 6.2811922910
MESH:D001321 Autistic Disorder Arachidonic Acid 3.0918582451
MESH:D001327 Autoimmune Diseases Cholecalciferol 4.5316142846
MESH:D001471 Barrett Esophagus Tretinoin 3.9116935849
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 7.4012125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 7.4016206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.2615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.4215746008
MESH:D001930 Brain Injuries Raloxifene 3.9716580743
MESH:D002545 Brain Ischemia Plant Extracts 4.2116041641
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 6.2620146248 17474063
MESH:D001943 Breast Neoplasms Calcitriol 6.2611237771
MESH:D001943 Breast Neoplasms Estradiol 6.2619861407 14630087 16675129 17018787 17289903 18497071 12948864 17261762
MESH:D001943 Breast Neoplasms gemcitabine 6.2617039268 18382427
MESH:D001943 Breast Neoplasms Genistein 6.2616873071 16541309 17200150
MESH:D001943 Breast Neoplasms Methylcholanthrene 6.2617474063
MESH:D001943 Breast Neoplasms Raloxifene 6.2615775269 17242785 17440819 17261762 16912660 17595753 15758505 17952589 17893378 16837676 15572757 17049068
MESH:D001943 Breast Neoplasms Tamoxifen 6.2619103187 11161223 20859285 16202921 19288272 20544844 19059307 18855134 18629630 19221464 20065188 19115204 16818667 20135344 16273361 18351453 18425577 19189210 18997820 18815881 18984771 17893378 19244106 19189212 17261762 19142967 17242785 15565566 19289846 19011961 20390343 17049068 19155303 16873071 21152245 19410462 18821012 19487384 20005174 15668708 19066611 21138602 19200415 19084267 17440819
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 6.2620435547
MESH:D001943 Breast Neoplasms Tretinoin 6.2616873071 16443354 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.0716813970
MESH:D002057 Burns, Chemical Plant Extracts 4.819625245
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.9416111702
MESH:D002277 Carcinoma Methylcholanthrene 6.9610545420
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 6.9616835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.0019066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.6316168501
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 9.9812619106 12907637 21507988
MESH:D006528 Carcinoma, Hepatocellular Estradiol 9.9816924424
MESH:D006528 Carcinoma, Hepatocellular Genistein 9.9816924424
MESH:D006528 Carcinoma, Hepatocellular Plant Extracts 9.9818834353
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 9.9816924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 9.981917145
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 6.4920419170
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 6.4911237771
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 6.4916096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 8.0017572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 8.0017572228
MESH:D006332 Cardiomegaly Plant Extracts 5.9617645561
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 5.9618670907 18850075 16120746
MESH:D002318 Cardiovascular Diseases Genistein 6.2816332659
MESH:D002318 Cardiovascular Diseases Raloxifene 6.2815775269
MESH:D002386 Cataract Tretinoin 2.7717460283
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 13.0912371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 13.0918566989
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 13.0916192471
MESH:D002471 Cell Transformation, Neoplastic monomethylarsonous acid 13.0919716837
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.0716129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.7216835633
MESH:D002779 Cholestasis Cyclosporine 11.4019486331
MESH:D002779 Cholestasis Ethinyl Estradiol 11.4016105132 17110522 16919318 17333356 17681005 11677210 15861022
MESH:D002779 Cholestasis Lithocholic Acid 11.4019965603
MESH:D002822 Choriocarcinoma Tretinoin 4.6316461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 8.5015668235 15340226 12621046 16354765 8697196
MESH:D002972 Cleft Palate Tretinoin 8.509407595
MESH:D002972 Cleft Palate triadimefon 8.5016781842
MESH:D003072 Cognition Disorders Raloxifene 4.1115800139
MESH:D003092 Colitis Tretinoin 3.2017035595
MESH:D003110 Colonic Neoplasms arsenite 7.4115037631
MESH:D003110 Colonic Neoplasms Calcium, Dietary 7.4117182828
MESH:D003110 Colonic Neoplasms Dexamethasone 7.4115824018
MESH:D003110 Colonic Neoplasms Genistein 7.4117182828
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.6217141729 14669216
MESH:D019465 Craniofacial Abnormalities Dexamethasone 4.8517728286
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 4.8510048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 4.859664655 16925845 9224671 10589399 14991402 17551590 9142499 8800419 9211117 9125849
MESH:D019465 Craniofacial Abnormalities triadimefon 4.8515834900 16875885
MESH:D003704 Dementia Methylmercury Compounds 4.5316140633
MESH:D003711 Demyelinating Diseases Tamoxifen 3.8619031437
MESH:D003865 Depressive Disorder, Major Raloxifene 3.7217474826
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 2.9312438553
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 3.8116647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 3.8117107852
MESH:D003928 Diabetic Nephropathies Estradiol 17.8719279558
MESH:D003928 Diabetic Nephropathies Plant Extracts 17.8719706694
MESH:D003928 Diabetic Nephropathies Raloxifene 17.8717451421 15920148 17308373
MESH:D003928 Diabetic Nephropathies Tamoxifen 17.8719279558
MESH:D003967 Diarrhea Dexamethasone 3.227237001
MESH:D056486 Drug-Induced Liver Injury Ketoconazole 3.6718289764
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.6720420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.3711462148
MESH:D004485 Eczema Dexamethasone 3.9712438553
MESH:D004487 Edema Arachidonic Acid 16.839831321 15177302 7990266 16716910 9599246 11698051
MESH:D004487 Edema Dexamethasone 16.8319703484
MESH:D004487 Edema Plant Extracts 16.8312787963
MESH:D004487 Edema Raloxifene 16.8315860553
MESH:D004487 Edema Tetrachlorodibenzodioxin 16.8312711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.1915322242 18230668 16714409
MESH:D004489 Edema, Cardiac Tretinoin 10.1918230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Am 80 23.5516819260
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 23.5515138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 23.5512538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 23.5515845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 23.5519031437
MESH:D004714 Endometrial Hyperplasia Genistein 4.0716402032
MESH:D016889 Endometrial Neoplasms Estradiol 14.8911473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Genistein 14.8911473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 14.8917893378 19155303 20544844 16202921
MESH:D016889 Endometrial Neoplasms Tretinoin 14.8916569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.5710568697 9294722
MESH:D004719 Endomyocardial Fibrosis Plant Extracts 5.1515268973
MESH:D004827 Epilepsy Plant Extracts 3.4519700373 19439326
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 1.8616530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.5311564622
MESH:D005124 Eye Abnormalities Tretinoin 7.539664655 16938888
MESH:D005234 Fatty Liver arsenite 24.7418296743
MESH:D005234 Fatty Liver Cyclosporine 24.7419224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 24.7415345470
MESH:D005234 Fatty Liver Plant Extracts 24.7415975614
MESH:D005234 Fatty Liver Raloxifene 24.7417473493
MESH:D005234 Fatty Liver Tamoxifen 24.7419224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 2.9116709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.9511858732
MESH:D005334 Fever Arachidonic Acid 4.2111852909
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.0114745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.6619069698
MESH:D005354 Fibrosarcoma Methylcholanthrene 4.4214633661 10962813
MESH:D005355 Fibrosis arsenite 17.0318296743
MESH:D005355 Fibrosis Cyclosporine 17.0312639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 17.0320067830
MESH:D005355 Fibrosis Tretinoin 17.0317994277
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.708708960
MESH:D005909 Glioblastoma Genistein 6.0516598420
MESH:D005909 Glioblastoma Tretinoin 6.0517312396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.0710696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 2.8316096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.6316084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 9.3820471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 9.3810048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 9.389664655 14991402
MESH:D006331 Heart Diseases Raloxifene 3.1711110106
MESH:D006333 Heart Failure Plant Extracts 3.5418097624
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.9015720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.8711000095
MESH:D006529 Hepatomegaly propiconazole 11.8217178689 17178688
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 11.8215340226 16120746 12621046
MESH:D006529 Hepatomegaly triadimefon 11.8217178688 17178689
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 2.877520565
MESH:D006558 Herpes Genitalis Estradiol 4.5015709030
MESH:D006561 Herpes Simplex Plant Extracts 4.1110715843
MESH:D015658 HIV Infections Plant Extracts 3.4012878215
MESH:D019584 Hot Flashes Estradiol 8.5817088409
MESH:D019584 Hot Flashes Plant Extracts 8.5817454163 16566672 14716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.5218606429 8697196 16354765 15340226 16959395
MESH:D006930 Hyperalgesia Tretinoin 2.8116870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.0616778211
MESH:D020138 Hyperhomocysteinemia Plant Extracts 4.0316484555
MESH:D006949 Hyperlipidemias Plant Extracts 4.0015975614 15268973
MESH:D006973 Hypertension Cyclosporine 10.5210903974
MESH:D006973 Hypertension Dexamethasone 10.5217042910
MESH:D006973 Hypertension Raloxifene 10.5217577099 15787275
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 10.5218850075 18670907
MESH:D007021 Hypospadias Ethinyl Estradiol 3.3016569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.9812013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.1417937319
MESH:D007249 Inflammation Arachidonic Acid 16.2015177302 17371808 9831321
MESH:D007249 Inflammation Dexamethasone 16.2011099482 8960868
MESH:D007249 Inflammation Flurbiprofen 16.2011099482
MESH:D007249 Inflammation Plant Extracts 16.2015997105 16366677 19332304 12787963
MESH:D007249 Inflammation Tamoxifen 16.2019457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 16.2012200463 12878042
MESH:D007333 Insulin Resistance Estradiol 2.6216393666 16627594
MESH:D007410 Intestinal Diseases Tretinoin 3.2617994277
MESH:D007414 Intestinal Neoplasms Plant Extracts 4.1712351151 12584176 12628509
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 14.5716580747
MESH:D007569 Jaw Abnormalities Tretinoin 14.5717551590 15992940
MESH:D007569 Jaw Abnormalities triadimefon 14.5715834900 15992940
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.9115604871
MESH:D007674 Kidney Diseases Cyclosporine 4.898314463 18776723 10903974
MESH:D007674 Kidney Diseases Estradiol 4.8915618244
MESH:D007680 Kidney Neoplasms Cyclosporine 9.9312371664
MESH:D007680 Kidney Neoplasms Estradiol 9.9315610895
MESH:D007680 Kidney Neoplasms Tamoxifen 9.9318625569
MESH:D007683 Kidney Tubular Necrosis, Acute Calcium 4.5216316344
MESH:D007889 Leiomyoma Raloxifene 4.0216973256
MESH:D016773 Leishmaniasis, Cutaneous Itraconazole 8.2014988693 11528583
MESH:D016773 Leishmaniasis, Cutaneous Ketoconazole 8.2019744259 1311351 2166429 8889330
MESH:D007898 Leishmaniasis, Visceral Ketoconazole 4.1511332679
MESH:D007938 Leukemia Genistein 5.4818980019 17468513
MESH:D007938 Leukemia Tretinoin 5.4817143497
MESH:D007948 Leukemia, Monocytic, Acute U 0126 4.7916972261
MESH:D007951 Leukemia, Myeloid Tretinoin 3.2419285840 16932348 16482212
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 4.1016294345 19850784 17596541
MESH:D015470 Leukemia, Myeloid, Acute Vitamin D 4.1020368581
MESH:D015473 Leukemia, Promyelocytic, Acute Am 80 6.9916531727 16819260
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 6.9917339181 17217047 19035177 19225113 19642359 17506722 16823087 16331271 17294898 16766008 16788101 12679006 17649720 17712046 17107899 16140955 9834237 15748426 17301526 17368321 16891316 19029980 19075265 17361223 16935935
MESH:D017880 Limb Deformities, Congenital Tretinoin 2.939224671
MESH:D008064 Lipidoses Ketoconazole 7.0417567588
MESH:D008064 Lipidoses Tamoxifen 7.0415342952 17567588
MESH:D008103 Liver Cirrhosis arsenite 6.1518296743
MESH:D008103 Liver Cirrhosis Plant Extracts 6.1517157831
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 9.6116718785
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 9.6114716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Genistein 9.6117823541
MESH:D008106 Liver Cirrhosis, Experimental Plant Extracts 9.6115479170
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 9.6118564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 9.6112878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 9.6116248980 18397230
MESH:D008107 Liver Diseases Plant Extracts 6.0117034775
MESH:D008107 Liver Diseases propiconazole 6.0119363144
MESH:D008107 Liver Diseases triadimefon 6.0119363144
MESH:D008113 Liver Neoplasms Aflatoxin B1 18.459163691 15890375 18177683 2125692
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 18.4521137059 20195826
MESH:D008113 Liver Neoplasms Plant Extracts 18.4519168119
MESH:D008113 Liver Neoplasms propiconazole 18.4519028983
MESH:D008113 Liver Neoplasms Tamoxifen 18.4516684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 18.4516984957
MESH:D008113 Liver Neoplasms triadimefon 18.4519028983
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 15.118603461
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 15.111399818 598648
MESH:D008114 Liver Neoplasms, Experimental propiconazole 15.1117178689
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 15.1112151625
MESH:D008114 Liver Neoplasms, Experimental triadimefon 15.1117178689
MESH:D008175 Lung Neoplasms Aflatoxin B1 11.4914755239
MESH:D008175 Lung Neoplasms arsenite 11.4916809336
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 11.4918569708 20869020 20464547 18520028 18816296 20135361 20064080 17053015 6695378
MESH:D008175 Lung Neoplasms Dexamethasone 11.4911195469 15824018
MESH:D008175 Lung Neoplasms Methylcholanthrene 11.4920970405 21163286 7750092 10545420 16337739 16271038 9230183 20512841 15390079 17909032 11893704 1399818 6695378
MESH:D008175 Lung Neoplasms Plant Extracts 11.4920869020
MESH:D008175 Lung Neoplasms Tamoxifen 11.4918625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 11.4911884234 19555203
MESH:D008178 Lupus Erythematosus, Cutaneous Rifampin 5.6111422169
MESH:D008180 Lupus Erythematosus, Systemic Rifampin 3.8111422169
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.2519428831
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 7.9816891317 11807958 11408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Genistein 7.9812929590 14578162
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 7.9811731420 19196722 14580682 19196723 16827153
MESH:D020149 Manganese Poisoning Estradiol 10.8919453300
MESH:D020149 Manganese Poisoning Tamoxifen 10.8919453300
MESH:D008527 Medulloblastoma Tretinoin 2.5617453147
MESH:D008545 Melanoma Tamoxifen 2.9319393235 12393984
MESH:D008545 Melanoma Tretinoin 2.9316752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.6615990972
MESH:D008569 Memory Disorders Methylmercury Compounds 4.4218436314
MESH:D008591 Meningomyelocele Tretinoin 3.9216940565
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.2616801185
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.0315863610
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 2.7916381670
MESH:D009069 Movement Disorders Methylmercury Compounds 4.8518436314
MESH:D009101 Multiple Myeloma Am 80 10.2017229644
MESH:D009101 Multiple Myeloma Dexamethasone 10.2015867202 16118317 15744524
MESH:D009101 Multiple Myeloma Raloxifene 10.2016497877
MESH:D009164 Mycobacterium Infections Rifampin 5.0218474467
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 6.499809623
MESH:D009190 Myelodysplastic Syndromes Tretinoin 6.4917596541
MESH:D009203 Myocardial Infarction Genistein 2.6317141266
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.6112213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 7.1816810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 7.1817141266
MESH:D009232 Myxoma Raloxifene 5.0316343187
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.3219393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.3319410462
MESH:D009369 Neoplasms Benzo(a)pyrene 4.0811141357
MESH:D009369 Neoplasms Tretinoin 4.0816946489 16594593
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.4719189210 19196722 19200415
MESH:D009389 Neovascularization, Pathologic arsenite 8.4315738583
MESH:D009389 Neovascularization, Pathologic Estradiol 8.4317289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.9117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 2.8519348381 18481113
MESH:D009421 Nervous System Malformations Estradiol 19.4111399458 16427766
MESH:D009421 Nervous System Malformations Genistein 19.4116427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 19.4114600291
MESH:D009421 Nervous System Malformations Tretinoin 19.419125849
MESH:D009436 Neural Tube Defects Tretinoin 2.719142499
MESH:D019954 Neurobehavioral Manifestations Plant Extracts 4.6817168769
MESH:D009765 Obesity Plant Extracts 3.0020132043 19056576
MESH:D014009 Onychomycosis Itraconazole 6.4019954708
MESH:D010024 Osteoporosis Calcium 14.2717882678
MESH:D010024 Osteoporosis Genistein 14.2719401787
MESH:D010024 Osteoporosis Raloxifene 14.2717882678 15775268 19059307
MESH:D010024 Osteoporosis Vitamin D 14.2717882678
MESH:D015663 Osteoporosis, Postmenopausal Genistein 8.5616169203
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 8.5615579764 17823083 15758505 17893378
MESH:D010051 Ovarian Neoplasms Estradiol 9.7519401270
MESH:D010051 Ovarian Neoplasms Genistein 9.7519005980
MESH:D010051 Ovarian Neoplasms Tretinoin 9.7516936753
MESH:D010051 Ovarian Neoplasms U 0126 9.7516211241
MESH:D010146 Pain Tretinoin 2.5016870215
MESH:D010190 Pancreatic Neoplasms gemcitabine 4.9517440100 11504793 18992248 16929163 18383843
MESH:D010190 Pancreatic Neoplasms Tretinoin 4.9515976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.2111578682
MESH:D010212 Papilloma Plant Extracts 3.9916517061 15173996
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.7212520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.0718163543
MESH:D011230 Precancerous Conditions Cyclosporine 2.7912371664
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.2421297632
MESH:D011297 Prenatal Exposure Delayed Effects Methylmercury Compounds 8.1718436314
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 8.1711118676 11896295 11222880 11399792
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.2615572423
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.4220887781
MESH:D011471 Prostatic Neoplasms Am 80 4.6016289102
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 4.6017292933
MESH:D011471 Prostatic Neoplasms Calcifediol 4.6016289102
MESH:D011471 Prostatic Neoplasms Calcitriol 4.6015754350 16289102 12479363 18247401 16644109
MESH:D011471 Prostatic Neoplasms Cholecalciferol 4.6017024972
MESH:D011471 Prostatic Neoplasms Estradiol 4.6016740699
MESH:D011471 Prostatic Neoplasms Flurbiprofen 4.6017409433
MESH:D011471 Prostatic Neoplasms Genistein 4.6016925846 15256057 15378649
MESH:D011471 Prostatic Neoplasms Ketoconazole 4.6017404083
MESH:D011471 Prostatic Neoplasms Plant Extracts 4.6014666653 17804756
MESH:D011471 Prostatic Neoplasms Raloxifene 4.6016220300 15731164 16536755
MESH:D011471 Prostatic Neoplasms Tamoxifen 4.6015067354
MESH:D011507 Proteinuria Tretinoin 3.1316636307
MESH:D011537 Pruritus Ethinyl Estradiol 2.8015861022 16919318
MESH:D011565 Psoriasis Am 80 5.4616819260
MESH:D011565 Psoriasis Cyclosporine 5.4616882103
MESH:D011625 Pterygium Tretinoin 4.2716723453
MESH:D011693 Purpura Raloxifene 5.0315770314
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 3.5411700416 18379247
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.3418990726
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.6216116481 16283617
MESH:D012871 Skin Diseases monomethylarsonous acid 3.2317431481
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 11.3710029692 19755658
MESH:D012878 Skin Neoplasms Plant Extracts 11.3715173996 16517061
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 11.3716192470
MESH:D012878 Skin Neoplasms Tretinoin 11.3716467112
MESH:D013088 Spermatocele Ethinyl Estradiol 9.8016709447
MESH:D013088 Spermatocele Tamoxifen 9.8016709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.5219457130
MESH:D013272 Stomach Diseases Dexamethasone 3.8115472012
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.192093021 20155912
MESH:D013274 Stomach Neoplasms Tretinoin 2.1917261132
MESH:D013276 Stomach Ulcer Dexamethasone 6.1715138204
MESH:D013276 Stomach Ulcer Plant Extracts 6.1718237397 17135157 15255614 18193104 12787963
MESH:D020521 Stroke Raloxifene 3.4116837676
MESH:D013705 Temporomandibular Joint Disorders Plant Extracts 4.9517997062
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.1411994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.7215669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.3712697716
MESH:D013964 Thyroid Neoplasms Tretinoin 6.2616026305 17045167
MESH:D013964 Thyroid Neoplasms triadimefon 6.2617178689
MESH:D013978 Tibial Fractures Estradiol 11.9519048282
MESH:D013978 Tibial Fractures Raloxifene 11.9519048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.3416051514
MESH:D014376 Tuberculosis Rifampin 7.3115236969 18397238
MESH:D014376 Tuberculosis Tretinoin 7.3116040207
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 10.0817053015
MESH:D001749 Urinary Bladder Neoplasms monomethylarsonous acid 10.0820375083
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 10.0817572228
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 10.0816712894 17572228 8653321
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.2316129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 2.8114692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.0816752155
MESH:D014605 Uveitis Cyclosporine 10.011336536
MESH:D014605 Uveitis Dexamethasone 10.011336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.0712125929
MESH:D054556 Venous Thromboembolism Raloxifene 4.6816837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.0714671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Plant Extracts 4.2418097624
MESH:D020257 Ventricular Remodeling Plant Extracts 4.8018097624
MESH:D014820 Vitiligo Tretinoin 3.5616761959
MESH:D014846 Vulvar Neoplasms Raloxifene 5.0316343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.7215886252
MESH:D009396 Wilms Tumor Tretinoin 3.5316287080
MESH:D014947 Wounds and Injuries Plant Extracts 3.8319894650 20213670
MESH:D014985 Xerophthalmia Cyclosporine 3.9117120751
Pathway ID Pathway Name
REACT:13433 Biological oxidations
REACT:15314 Hormone biosynthesis
REACT:22258 Metabolism of lipids and lipoproteins
REACT:11193 Metabolism of vitamins and cofactors
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA27097
    • No data
    Releated disease ID Related disease Name
    PA443450Asthma
    PA443879Dermatitis, Atopic
    PA445185Osteomalacia
    Releated drug ID Related drug Name
    PA451250rifampin
    PA448717calcitriol
    Drug Bank Top
    No data
    Drugbank ID Action Drug Name Description
    DB00136 inducer Calcitriol Essential Vitamin;Antihypocalcemic Agents;Antihypoparathyroid Agents;Vitamins (Vitamin D);Bone Density Conservation Agents;Calcium Channel Agonists;Vitamins
    DB00146 substrate Calcidiol Antihypocalcemic Agents;Antihypoparathyroid Agents;Vitamins (Vitamin D);Bone Density Conservation Agents;Vitamins
    DB00153 substrate Timed Release Multi Vitamin with Chelated Minerals Essential Vitamin;Antihypocalcemic Agents;Antihypoparathyroid Agents;Vitamins (Vitamin D);Bone Density Conservation Agents;Vitamins
    DB00910 substrate Paricalcitol
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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