Annotation Detail for CYP26A1
Basic Information Top
| Gene Symbol: | CYP26A1 ( CP26,CYP26,P450RAI,P450RAI1 ) |
|---|---|
| Gene Full Name: | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| Band: | 10q23.33 |
| Quick Links | Entrez ID:1592; OMIM: 602239; Uniprot ID:CP26A_HUMAN; ENSEMBL ID: ENSG00000095596; HGNC ID: 2603 |
| Relate to Another Database: | SFARIGene; denovo-db |
| No data |
| Pathway ID | Pathway Name |
|---|---|
| hsa00830 | Retinol metabolism |
| Pathway ID | Pathway Name |
|---|---|
| Biological oxidations |
| No data |
| No data |
| Pathway ID | Pathway Name |
|---|---|
| 500202 | Vitamins |
| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| C016403 | 2,4-dinitrotoluene | 2,4-dinitrotoluene affects the expression of CYP26A1 mRNA | affects expression | 21346803 |
| C023514 | 2,6-dinitrotoluene | 2,6-dinitrotoluene affects the expression of CYP26A1 mRNA | affects expression | 21346803 |
| C038864 | 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid | 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in increased expression of CYP26A1 mRNA | increases expression | 15589975 |
| C038864 | 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid | AGN 193109 inhibits the reaction [4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in increased expression of CYP26A1 mRNA] | decreases reaction|increases expression | 15589975 |
| C009505 | 4,4'-diaminodiphenylmethane | 4,4'-diaminodiphenylmethane results in increased expression of CYP26A1 mRNA | increases expression | 18648102 |
| C019429 | 4-hydroxyretinoic acid | 4-hydroxyretinoic acid affects the expression of CYP26A1 mRNA | affects expression | 16054125 |
| C019429 | 4-hydroxyretinoic acid | CYP26A1 protein results in increased chemical synthesis of 4-hydroxyretinoic acid | increases chemical synthesis | 17460545 |
| C002202 | 4-oxoretinoic acid | 4-oxoretinoic acid affects the expression of CYP26A1 mRNA | affects expression | 16054125 |
| C002202 | 4-oxoretinoic acid | CYP26A1 protein results in increased chemical synthesis of 4-oxoretinoic acid | increases chemical synthesis | 17460545 |
| C041819 | 4-oxoretinol | CYP26A1 protein affects the chemical synthesis of 4-oxoretinol | affects chemical synthesis | 10557354 |
| D000082 | Acetaminophen | Acetaminophen affects the expression of CYP26A1 mRNA | affects expression | 17562736 |
| C096920 | AGN 193109 | AGN 193109 inhibits the reaction [4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in increased expression of CYP26A1 mRNA] | decreases reaction|increases expression | 15589975 |
| C096920 | AGN 193109 | AGN 193109 inhibits the reaction [Aldrin results in increased expression of CYP26A1 mRNA] | decreases reaction|increases expression | 15589975 |
| C096920 | AGN 193109 | AGN 193109 inhibits the reaction [Chlordan results in increased expression of CYP26A1 mRNA] | decreases reaction|increases expression | 15589975 |
| C096920 | AGN 193109 | AGN 193109 inhibits the reaction [Dieldrin results in increased expression of CYP26A1 mRNA] | decreases reaction|increases expression | 15589975 |
| C096920 | AGN 193109 | AGN 193109 inhibits the reaction [Endosulfan results in increased expression of CYP26A1 mRNA] | decreases reaction|increases expression | 15589975 |
| C096920 | AGN 193109 | AGN 193109 inhibits the reaction [Endrin results in increased expression of CYP26A1 mRNA] | decreases reaction|increases expression | 15589975 |
| D000452 | Aldrin | AGN 193109 inhibits the reaction [Aldrin results in increased expression of CYP26A1 mRNA] | decreases reaction|increases expression | 15589975 |
| D000452 | Aldrin | Aldrin results in increased expression of CYP26A1 mRNA | increases expression | 15589975 |
| C103303 | alitretinoin | alitretinoin results in increased expression of CYP26A1 mRNA | increases expression | 16194896 |
| C103303 | alitretinoin | alitretinoin results in increased expression of CYP26A1 mRNA | increases expression | 16688765 |
| D013196 | Dihydrotestosterone | [Retinaldehyde co-treated with Dihydrotestosterone] results in increased expression of CYP26A1 mRNA | affects cotreatment|increases expression | 17526768 |
| D000638 | Amiodarone | Amiodarone results in increased expression of CYP26A1 mRNA | increases expression | 19774075 |
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of CYP26A1 mRNA | affects expression | 16483693 |
| D000841 | Anisomycin | Anisomycin inhibits the reaction [Tretinoin results in increased expression of CYP26A1 mRNA] | decreases reaction|increases expression | 16038797 |
| D001151 | Arsenic | Arsenic affects the reaction [Tretinoin results in increased expression of CYP26A1 mRNA] | affects reaction|increases expression | 18288313 |
| C006632 | arsenic trioxide | arsenic trioxide inhibits the reaction [Tretinoin results in increased expression of CYP26A1 mRNA] | decreases reaction|increases expression | 15688020 |
| D019324 | beta-Naphthoflavone | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP26A1 mRNA | affects cotreatment|increases expression | 18164116 |
| D019207 | beta Carotene | beta Carotene results in increased expression of CYP26A1 mRNA | increases expression | 16186334 |
| C095105 | bexarotene | bexarotene results in increased expression of CYP26A1 mRNA | increases expression | 17178900 |
| C402892 | BMS453 | BMS453 inhibits the reaction [retinol acetate results in increased expression of CYP26A1 mRNA] | decreases reaction|increases expression | 16322074 |
| D002706 | Chlordan | AGN 193109 inhibits the reaction [Chlordan results in increased expression of CYP26A1 mRNA] | decreases reaction|increases expression | 15589975 |
| D002706 | Chlordan | Chlordan results in increased expression of CYP26A1 mRNA | increases expression | 15589975 |
| C019304 | ciprofibrate | ciprofibrate results in decreased expression of CYP26A1 mRNA | decreases expression | 12771043 |
| C057862 | cyanoginosin LR | cyanoginosin LR results in decreased expression of CYP26A1 mRNA | decreases expression | 17383702 |
| D003633 | Dichlorodiphenyl Dichloroethylene | Dichlorodiphenyl Dichloroethylene results in decreased expression of CYP26A1 mRNA | decreases expression | 16707153 |
| D003633 | Dichlorodiphenyl Dichloroethylene | Dichlorodiphenyl Dichloroethylene results in decreased expression of CYP26A1 protein | decreases expression | 16707153 |
| D004026 | Dieldrin | AGN 193109 inhibits the reaction [Dieldrin results in increased expression of CYP26A1 mRNA] | decreases reaction|increases expression | 15589975 |
| D004026 | Dieldrin | Dieldrin results in increased expression of CYP26A1 mRNA | increases expression | 15589975 |
| D004052 | Diethylnitrosamine | Diethylnitrosamine results in decreased expression of CYP26A1 mRNA | decreases expression | 12771043 |
| D004052 | Diethylnitrosamine | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP26A1 mRNA | affects cotreatment|increases expression | 18164116 |
| D011397 | Promegestone | [Promegestone co-treated with Estradiol] results in increased expression of CYP26A1 mRNA | affects cotreatment|increases expression | 16955405 |
| D011397 | Promegestone | Promegestone results in increased expression of CYP26A1 mRNA | increases expression | 16955405 |
| D004726 | Endosulfan | AGN 193109 inhibits the reaction [Endosulfan results in increased expression of CYP26A1 mRNA] | decreases reaction|increases expression | 15589975 |
| D004726 | Endosulfan | Endosulfan results in increased expression of CYP26A1 mRNA | increases expression | 15589975 |
| D004732 | Endrin | AGN 193109 inhibits the reaction [Endrin results in increased expression of CYP26A1 mRNA] | decreases reaction|increases expression | 15589975 |
| D004732 | Endrin | Endrin results in increased expression of CYP26A1 mRNA | increases expression | 15589975 |
| D004958 | Estradiol | [Progesterone co-treated with Estradiol] results in increased expression of CYP26A1 mRNA | affects cotreatment|increases expression | 17404688 |
| D004958 | Estradiol | [Promegestone co-treated with Estradiol] results in increased expression of CYP26A1 mRNA | affects cotreatment|increases expression | 16955405 |
| D017313 | Fenretinide | Fenretinide results in increased expression of CYP26A1 mRNA | increases expression | 15291358 |
| C061121 | liarozole | liarozole results in decreased activity of CYP26A1 protein | decreases activity | 15597402 16279770 |
| D008070 | Lipopolysaccharides | Lipopolysaccharides inhibits the reaction [Tretinoin results in increased expression of CYP26A1 mRNA] | decreases reaction|increases expression | 17185629 |
| D010634 | Phenobarbital | Phenobarbital results in increased expression of CYP26A1 mRNA | increases expression | 19270015 19482888 |
| C006253 | pirinixic acid | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of CYP26A1 mRNA | affects binding|decreases expression|increases activity | 19710929 |
| D011374 | Progesterone | [Progesterone co-treated with Estradiol] results in increased expression of CYP26A1 mRNA | affects cotreatment|increases expression | 17404688 |
| D011374 | Progesterone | Progesterone results in increased expression of CYP26A1 mRNA | increases expression | 17404688 |
| D011374 | Progesterone | Progesterone affects the expression of CYP26A1 mRNA | affects expression | 17251523 |
| D011374 | Progesterone | [Progesterone results in increased activity of PGR protein] which results in increased expression of CYP26A1 mRNA | increases activity|increases expression | 15845616 |
| D011374 | Progesterone | Progesterone results in decreased expression of CYP26A1 | decreases expression | 17510236 |
| D011691 | Puromycin | [Tretinoin co-treated with Puromycin] results in increased expression of CYP26A1 mRNA | affects cotreatment|increases expression | 15977162 |
| C406527 | R 115866 | [R 115866 co-treated with Vitamin A] results in increased expression of CYP26A1 mRNA | affects cotreatment|increases expression | 17510468 |
| C406527 | R 115866 | [R 115866 results in decreased activity of CYP26A1 protein] which results in increased abundance of Tretinoin | decreases activity|increases abundance | 17510468 |
| D012172 | Retinaldehyde | [Retinaldehyde co-treated with Dihydrotestosterone] results in increased expression of CYP26A1 mRNA | affects cotreatment|increases expression | 17526768 |
| D012172 | Retinaldehyde | Retinaldehyde results in increased expression of CYP26A1 mRNA | increases expression | 17526768 |
| D015474 | Isotretinoin | Isotretinoin results in increased expression of CYP26A1 mRNA | increases expression | 16194896 17486130 |
| C009166 | retinol acetate | BMS453 inhibits the reaction [retinol acetate results in increased expression of CYP26A1 mRNA] | decreases reaction|increases expression | 16322074 |
| C009166 | retinol acetate | retinol acetate results in increased expression of CYP26A1 mRNA | increases expression | 16322074 |
| D013629 | Tamoxifen | Tamoxifen affects the expression of CYP26A1 mRNA | affects expression | 14699072 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in decreased expression of CYP26A1 mRNA | decreases expression | 16443690 |
| D013752 | Tetracycline | Tetracycline results in decreased expression of CYP26A1 mRNA | decreases expression | 16917069 |
| D014212 | Tretinoin | CYP26A1 protein inhibits the reaction [Tretinoin results in increased expression of CLDN1 mRNA] | decreases reaction|increases expression | 17035595 |
| D014212 | Tretinoin | CYP26A1 protein inhibits the reaction [Tretinoin results in increased expression of CLDN4 mRNA] | decreases reaction|increases expression | 17035595 |
| D014212 | Tretinoin | CYP26A1 protein inhibits the reaction [Tretinoin results in increased expression of OCLN mRNA] | decreases reaction|increases expression | 17035595 |
| D014212 | Tretinoin | CYP26A1 protein inhibits the reaction [Tretinoin results in increased expression of TJP1 mRNA] | decreases reaction|increases expression | 17035595 |
| D014212 | Tretinoin | CYP26A1 protein results in increased degradation of Tretinoin | increases degradation | 17035595 |
| D014212 | Tretinoin | [Tretinoin co-treated with Puromycin] results in increased expression of CYP26A1 mRNA | affects cotreatment|increases expression | 15977162 |
| D014212 | Tretinoin | Tretinoin results in increased expression of CYP26A1 mRNA | increases expression | 15977162 |
| D014212 | Tretinoin | Tretinoin affects the expression of CYP26A1 mRNA | affects expression | 16054125 |
| D014212 | Tretinoin | Tretinoin results in increased expression of CYP26A1 mRNA | increases expression | 17164423 18230668 16885356 |
| D014212 | Tretinoin | Arsenic affects the reaction [Tretinoin results in increased expression of CYP26A1 mRNA] | affects reaction|increases expression | 18288313 |
| D014212 | Tretinoin | CYP26A1 exon SNP results in decreased metabolism of Tretinoin | decreases metabolic processing | 17460545 |
| D014212 | Tretinoin | CYP26A1 protein polymorphism results in decreased metabolism of Tretinoin | decreases metabolic processing | 17460545 |
| D014212 | Tretinoin | CYP26A1 protein results in increased metabolism of Tretinoin | increases metabolic processing | 16194896 17460545 17486130 |
| D014212 | Tretinoin | RARA protein affects the reaction [Tretinoin results in increased expression of CYP26A1 mRNA] | affects reaction|increases expression | 16194896 |
| D014212 | Tretinoin | [Tretinoin co-treated with IL8 protein] results in increased expression of CYP26A1 mRNA | affects cotreatment|increases expression | 17218384 |
| D014212 | Tretinoin | [Tretinoin co-treated with RARA protein co-treated with RXRA protein] results in increased expression of CYP26A1 mRNA | affects cotreatment|increases expression | 17244623 |
| D014212 | Tretinoin | Tretinoin results in increased expression of CYP26A1 mRNA | increases expression | 15291358 12870655 17486130 17431108 16882163 16012519 18288313 17138961 16194896 17218384 |
| D014212 | Tretinoin | Anisomycin inhibits the reaction [Tretinoin results in increased expression of CYP26A1 mRNA] | decreases reaction|increases expression | 16038797 |
| D014212 | Tretinoin | arsenic trioxide inhibits the reaction [Tretinoin results in increased expression of CYP26A1 mRNA] | decreases reaction|increases expression | 15688020 |
| D014212 | Tretinoin | CYP26A1 protein affects the degradation of Tretinoin | affects degradation | 16688765 |
| D014212 | Tretinoin | CYP26A1 protein inhibits the reaction [Tretinoin results in decreased expression of FGF8 mRNA] | decreases expression|decreases reaction | 12588859 |
| D014212 | Tretinoin | CYP26A1 protein inhibits the reaction [Tretinoin results in decreased expression of WNT3A mRNA] | decreases expression|decreases reaction | 12588859 |
| D014212 | Tretinoin | CYP26A1 protein results in decreased susceptibility to Tretinoin | decreases response to substance | 12588859 |
| D014212 | Tretinoin | CYP26A1 protein results in increased degradation of Tretinoin | increases degradation | 12588859 |
| D014212 | Tretinoin | CYP26A1 protein results in increased metabolism of Tretinoin | increases metabolic processing | 19010342 |
| D014212 | Tretinoin | RARA protein affects the reaction [Tretinoin affects the expression of CYP26A1 mRNA] | affects expression|affects reaction | 16261163 |
| D014212 | Tretinoin | Tretinoin promotes the reaction [[RARG protein binds to RXRA protein] which binds to CYP26A1 promoter] | affects binding|increases reaction | 16053444 |
| D014212 | Tretinoin | Tretinoin results in increased expression of CYP26A1 | increases expression | 10862743 |
| D014212 | Tretinoin | Tretinoin results in increased expression of CYP26A1 mRNA | increases expression | 16038797 16053444 16688765 15688020 16788091 19897914 16604517 |
| D014212 | Tretinoin | Lipopolysaccharides inhibits the reaction [Tretinoin results in increased expression of CYP26A1 mRNA] | decreases reaction|increases expression | 17185629 |
| D014212 | Tretinoin | [R 115866 results in decreased activity of CYP26A1 protein] which results in increased abundance of Tretinoin | decreases activity|increases abundance | 17510468 |
| D014212 | Tretinoin | Tretinoin results in increased expression of CYP26A1 mRNA | increases expression | 17185629 17510468 |
| D014212 | Tretinoin | CYP26A1 protein results in increased metabolism of Tretinoin | increases metabolic processing | 16979153 |
| D014212 | Tretinoin | CYP26A1 protein results in increased degradation of Tretinoin | increases degradation | 17510468 |
| D014212 | Tretinoin | CYP26A1 protein results in increased metabolism of and results in decreased activity of Tretinoin | decreases activity|increases metabolic processing | 16933217 |
| D014212 | Tretinoin | CYP26A1 protein results in increased metabolism of and results in increased degradation of Tretinoin | increases degradation|increases metabolic processing | 10862743 |
| D014212 | Tretinoin | CYP26A1 protein results in increased metabolism of Tretinoin | increases metabolic processing | 16837774 16955405 |
| C032910 | triadimefon | triadimefon results in increased expression of CYP26A1 mRNA | increases expression | 19010342 |
| C032910 | triadimefon | triadimefon results in increased expression of CYP26A1 mRNA | increases expression | 16875885 |
| D014801 | Vitamin A | Vitamin A results in increased expression of CYP26A1 mRNA | increases expression | 16230703 |
| D014801 | Vitamin A | [Vitamin A co-treated with RARA protein co-treated with RXRA protein] results in increased expression of CYP26A1 mRNA | affects cotreatment|increases expression | 17244623 |
| D014801 | Vitamin A | Vitamin A results in increased expression of CYP26A1 mRNA | increases expression | 16194896 |
| D014801 | Vitamin A | CYP26A1 protein affects the metabolism of Vitamin A | affects metabolic processing | 10557354 |
| D014801 | Vitamin A | [R 115866 co-treated with Vitamin A] results in increased expression of CYP26A1 mRNA | affects cotreatment|increases expression | 17510468 |
| D002762 | Cholecalciferol | Cholecalciferol results in increased expression of CYP26A1 mRNA | increases expression | 17170073 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000008 | Abdominal Neoplasms | Tamoxifen | 4.02 | 14745880 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Isotretinoin | 11.36 | 18769834 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Phenobarbital | 11.36 | 6195326 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Tetrachlorodibenzodioxin | 11.36 | 15322242 11752688 14514962 | |
| MESH:D000015 | Abnormalities, Multiple | Isotretinoin | 9.22 | 18769834 | |
| MESH:D000015 | Abnormalities, Multiple | Vitamin A | 9.22 | 10992263 | |
| MESH:D000138 | Acidosis | Ammonium Chloride | 3.04 | 18287403 | |
| MESH:D017486 | Acneiform Eruptions | Isotretinoin | 5.75 | 16232082 | |
| MESH:D000152 | Acne Vulgaris | Isotretinoin | 4.95 | 18769834 16185265 | |
| MESH:D055371 | Acute Lung Injury | Lipopolysaccharides | 7.46 | 18653653 11850527 | |
| MESH:D055371 | Acute Lung Injury | pirinixic acid | 7.46 | 18653653 | |
| MESH:D000230 | Adenocarcinoma | arsenic trioxide | 6.28 | 11798837 19825857 | |
| MESH:D000230 | Adenocarcinoma | Estradiol | 6.28 | 11473722 | |
| MESH:D000230 | Adenocarcinoma | Fenretinide | 6.28 | 10697514 | |
| MESH:D000236 | Adenoma | 4,4'-diaminodiphenylmethane | 9.37 | 3712494 | |
| MESH:D000236 | Adenoma | beta-Naphthoflavone | 9.37 | 19389873 | |
| MESH:D000236 | Adenoma | Diethylnitrosamine | 9.37 | 6695378 10737359 | |
| MESH:D018248 | Adenoma, Liver Cell | Diethylnitrosamine | 20.61 | 19052882 19061943 16434500 17620307 18056438 17162532 | |
| MESH:D018248 | Adenoma, Liver Cell | Phenobarbital | 20.61 | 17620307 | |
| MESH:D018248 | Adenoma, Liver Cell | pirinixic acid | 20.61 | 16434500 | |
| MESH:D018248 | Adenoma, Liver Cell | Tetrachlorodibenzodioxin | 20.61 | 16835633 | |
| MESH:D011125 | Adenomatous Polyposis Coli | marker/mechanism | 16885356 | ||
| MESH:D018246 | Adrenocortical Adenoma | Arsenic | 4.68 | 17306315 | |
| MESH:D000382 | Agricultural Workers' Diseases | Dichlorodiphenyl Dichloroethylene | 4.29 | 16487989 | |
| MESH:D000505 | Alopecia | Tretinoin | 3.20 | 15955085 | |
| MESH:D000740 | Anemia | Tetrachlorodibenzodioxin | 7.48 | 11748828 | |
| MESH:D000740 | Anemia | Vitamin A | 7.48 | 16960172 | |
| MESH:D018798 | Anemia, Iron-Deficiency | Vitamin A | 4.35 | 16960172 | |
| MESH:D000799 | Angioedema | Acetaminophen | 3.32 | 10982225 | |
| MESH:D001145 | Arrhythmias, Cardiac | Amiodarone | 3.35 | 18218290 18057881 20041841 | |
| MESH:D020261 | Arsenic Poisoning | Arsenic | 2.70 | 18414634 16251483 12569548 16835338 | |
| MESH:D001169 | Arthritis, Experimental | Tretinoin | 2.75 | 16412693 | |
| MESH:D001172 | Arthritis, Rheumatoid | Tretinoin | 2.13 | 16292516 | |
| MESH:D001249 | Asthma | Tretinoin | 4.59 | 16456186 | |
| MESH:D001249 | Asthma | Vitamin A | 4.59 | 16732791 | |
| MESH:D050197 | Atherosclerosis | Arsenic | 2.93 | 12928151 19371607 | |
| MESH:D001281 | Atrial Fibrillation | Amiodarone | 3.51 | 19698954 18651412 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.48 | 18445737 | |
| MESH:D001327 | Autoimmune Diseases | Cholecalciferol | 4.53 | 16142846 | |
| MESH:D001471 | Barrett Esophagus | Tretinoin | 3.91 | 16935849 | |
| MESH:D001660 | Biliary Tract Diseases | 4,4'-diaminodiphenylmethane | 4.49 | 11289319 1440618 | |
| MESH:D001778 | Blood Coagulation Disorders | Amiodarone | 23.90 | 19483382 | |
| MESH:D001778 | Blood Coagulation Disorders | arsenic trioxide | 23.90 | 16206674 | |
| MESH:D001778 | Blood Coagulation Disorders | pirinixic acid | 23.90 | 19483382 | |
| MESH:D001778 | Blood Coagulation Disorders | Tetrachlorodibenzodioxin | 23.90 | 12125929 | |
| MESH:D001778 | Blood Coagulation Disorders | Tretinoin | 23.90 | 16206674 16197459 | |
| MESH:D001836 | Body Weight Changes | Tetrachlorodibenzodioxin | 3.26 | 15340226 | |
| MESH:D001848 | Bone Diseases, Developmental | Tetrachlorodibenzodioxin | 2.42 | 15746008 | |
| MESH:D020201 | Brain Hemorrhage, Traumatic | Progesterone | 4.81 | 17868700 | |
| MESH:D001930 | Brain Injuries | Progesterone | 3.75 | 15665606 15380490 15845082 | |
| MESH:D002545 | Brain Ischemia | beta Carotene | 4.58 | 16157235 | |
| MESH:D001932 | Brain Neoplasms | Fenretinide | 3.91 | 16187019 | |
| MESH:D001943 | Breast Neoplasms | alitretinoin | 7.45 | 16344269 | |
| MESH:D001943 | Breast Neoplasms | bexarotene | 7.45 | 16818667 16344269 | |
| MESH:D001943 | Breast Neoplasms | Dichlorodiphenyl Dichloroethylene | 7.45 | 15061365 | |
| MESH:D001943 | Breast Neoplasms | Dieldrin | 7.45 | 15770527 11859874 | |
| MESH:D001943 | Breast Neoplasms | Diethylnitrosamine | 7.45 | 17474063 | |
| MESH:D001943 | Breast Neoplasms | Estradiol | 7.45 | 17261762 16675129 14630087 19861407 12948864 18497071 17289903 17018787 | |
| MESH:D001943 | Breast Neoplasms | Fenretinide | 7.45 | 16601279 | |
| MESH:D001943 | Breast Neoplasms | Progesterone | 7.45 | 17614352 15562024 16175315 | |
| MESH:D001943 | Breast Neoplasms | Tamoxifen | 7.45 | 19084267 16273361 16202921 19155303 19189212 19244106 19142967 19066611 19189210 19288272 18351453 19410462 19011961 11161223 18855134 17261762 15668708 20859285 20544844 19103187 17440819 18821012 19487384 21138602 19221464 18984771 16873071 16818667 19115204 20390343 17049068 17242785 17893378 20005174 15565566 19200415 18815881 20135344 20065188 18425577 19059307 19289846 18997820 21152245 18629630 | |
| MESH:D001943 | Breast Neoplasms | Tetrachlorodibenzodioxin | 7.45 | 20435547 | |
| MESH:D001943 | Breast Neoplasms | Tretinoin | 7.45 | 16166294 16443354 16873071 | |
| MESH:D001997 | Bronchopulmonary Dysplasia | Tretinoin | 11.30 | 16813970 | |
| MESH:D001997 | Bronchopulmonary Dysplasia | Vitamin A | 11.30 | 17426644 17377406 | |
| MESH:D002051 | Burkitt Lymphoma | arsenic trioxide | 3.85 | 11589617 | |
| MESH:D002181 | Candidiasis, Vulvovaginal | Estradiol | 3.94 | 16111702 | |
| MESH:D002277 | Carcinoma | Tetrachlorodibenzodioxin | 2.39 | 16835633 | |
| MESH:D002280 | Carcinoma, Basal Cell | Arsenic | 3.28 | 15504454 17687452 | |
| MESH:D018270 | Carcinoma, Ductal, Breast | Tamoxifen | 4.00 | 19066611 | |
| MESH:D018236 | Carcinoma, Embryonal | Tretinoin | 4.63 | 16168501 | |
| MESH:D006528 | Carcinoma, Hepatocellular | 2,4-dinitrotoluene | 26.57 | 16705839 | |
| MESH:D006528 | Carcinoma, Hepatocellular | 2,6-dinitrotoluene | 26.57 | 16705839 | |
| MESH:D006528 | Carcinoma, Hepatocellular | 4,4'-diaminodiphenylmethane | 26.57 | 7296757 3581430 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 26.57 | 3084413 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Arsenic | 26.57 | 16507464 17306315 | |
| MESH:D006528 | Carcinoma, Hepatocellular | arsenic trioxide | 26.57 | 15073043 16217749 11135700 14691202 15553829 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Diethylnitrosamine | 26.57 | 16288022 18056438 16569478 18691550 18210153 16681979 19208518 19394651 20214788 19335982 17978847 3581430 20524982 18665156 17138121 20084675 17173139 16779866 19822196 20432363 20727157 11831363 18506893 19519916 16502159 10737359 19701751 16807293 17761372 18785209 19539802 21159647 16935385 18971187 18393292 19418558 3084413 20935162 19171122 17428255 20007298 18788625 16328049 16540662 19052882 19383236 16878318 16830150 17055752 17162532 10672840 19107877 19919837 20514400 18494052 20512989 16698587 18978308 20101231 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Estradiol | 26.57 | 16924424 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Fenretinide | 26.57 | 17159502 16270382 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Phenobarbital | 26.57 | 1701930 20007298 20935162 17173139 6705139 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Tamoxifen | 26.57 | 16924424 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Tretinoin | 26.57 | 1917145 | |
| MESH:D002289 | Carcinoma, Non-Small-Cell Lung | bexarotene | 3.03 | 16247446 | |
| MESH:D002291 | Carcinoma, Papillary | arsenic trioxide | 4.35 | 19014326 | |
| MESH:D002292 | Carcinoma, Renal Cell | 4,4'-diaminodiphenylmethane | 2.41 | 7296757 | |
| MESH:D018288 | Carcinoma, Small Cell | arsenic trioxide | 3.66 | 12490120 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Arsenic | 9.41 | 18922899 17687452 15504454 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Fenretinide | 9.41 | 16274795 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Isotretinoin | 9.41 | 11237771 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Tretinoin | 9.41 | 16096774 16051514 | |
| MESH:D002295 | Carcinoma, Transitional Cell | Arsenic | 8.00 | 18640142 | |
| MESH:D002295 | Carcinoma, Transitional Cell | Tamoxifen | 8.00 | 17572228 | |
| MESH:D006332 | Cardiomegaly | Tetrachlorodibenzodioxin | 2.07 | 18850075 18670907 16120746 | |
| MESH:D002311 | Cardiomyopathy, Dilated | Amiodarone | 2.69 | 15710769 19225199 | |
| MESH:D002318 | Cardiovascular Diseases | Arsenic | 3.09 | 15738583 19152805 17938729 | |
| MESH:D002340 | Carotid Artery Diseases | Arsenic | 3.87 | 16973168 18022660 | |
| MESH:D002341 | Carotid Artery Thrombosis | Amiodarone | 4.56 | 18974383 | |
| MESH:D002386 | Cataract | Acetaminophen | 6.15 | 10977129 | |
| MESH:D002386 | Cataract | Tretinoin | 6.15 | 17460283 | |
| MESH:D002471 | Cell Transformation, Neoplastic | 2,6-dinitrotoluene | 13.01 | 6135515 | |
| MESH:D002471 | Cell Transformation, Neoplastic | 4,4'-diaminodiphenylmethane | 13.01 | 7505956 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Diethylnitrosamine | 13.01 | 2727394 17174075 7505956 21159647 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Estradiol | 13.01 | 18566989 | |
| MESH:D002493 | Central Nervous System Diseases | Phenobarbital | 3.75 | 4080065 | |
| MESH:D018290 | Cervical Intraepithelial Neoplasia | Fenretinide | 11.25 | 16154183 | |
| MESH:D018290 | Cervical Intraepithelial Neoplasia | Tretinoin | 11.25 | 16129372 | |
| MESH:D015362 | Child Nutrition Disorders | Vitamin A | 4.95 | 16153327 | |
| MESH:D018281 | Cholangiocarcinoma | Diethylnitrosamine | 7.87 | 19052882 | |
| MESH:D018281 | Cholangiocarcinoma | Tetrachlorodibenzodioxin | 7.87 | 16835633 | |
| MESH:D002779 | Cholestasis | 4,4'-diaminodiphenylmethane | 11.31 | 19486331 9022650 | |
| MESH:D002779 | Cholestasis | pirinixic acid | 11.31 | 19176532 | |
| MESH:D002779 | Cholestasis | Vitamin A | 11.31 | 16175620 | |
| MESH:D002822 | Choriocarcinoma | Tretinoin | 4.63 | 16461808 | |
| MESH:D002972 | Cleft Palate | Tetrachlorodibenzodioxin | 12.16 | 15668235 8697196 12621046 15340226 16354765 | |
| MESH:D002972 | Cleft Palate | Tretinoin | 12.16 | 9407595 | |
| MESH:D002972 | Cleft Palate | triadimefon | 12.16 | 16781842 | |
| MESH:D002972 | Cleft Palate | Vitamin A | 12.16 | 16054864 | |
| MESH:D003092 | Colitis | Tretinoin | 3.20 | 17035595 | |
| MESH:D003110 | Colonic Neoplasms | marker/mechanism | 16885356 | ||
| MESH:D003110 | Colonic Neoplasms | Vitamin A | 2.95 | 16267017 17219422 | |
| MESH:D015179 | Colorectal Neoplasms | arsenic trioxide | 2.65 | 20501625 | |
| MESH:D015179 | Colorectal Neoplasms | Fenretinide | 2.65 | 17273769 | |
| MESH:D000013 | Congenital Abnormalities | Tetrachlorodibenzodioxin | 2.62 | 14669216 17141729 | |
| MESH:D023903 | Coronary Restenosis | arsenic trioxide | 3.69 | 12609071 | |
| MESH:D019465 | Craniofacial Abnormalities | arsenic trioxide | 8.48 | 10525206 | |
| MESH:D019465 | Craniofacial Abnormalities | Isotretinoin | 8.48 | 18769834 9879862 | |
| MESH:D019465 | Craniofacial Abnormalities | Tetrachlorodibenzodioxin | 8.48 | 10048152 15322242 20055451 | |
| MESH:D019465 | Craniofacial Abnormalities | Tretinoin | 8.48 | 9664655 17551590 14991402 16925845 9224671 10589399 8800419 9125849 9211117 9142499 | |
| MESH:D019465 | Craniofacial Abnormalities | triadimefon | 8.48 | 16875885 15834900 | |
| MESH:D019465 | Craniofacial Abnormalities | Vitamin A | 8.48 | 10992263 | |
| MESH:D003490 | Cyanosis | 2,4-dinitrotoluene | 15.97 | 18551238 | |
| MESH:D003490 | Cyanosis | 2,6-dinitrotoluene | 15.97 | 18551238 | |
| MESH:D003490 | Cyanosis | Endosulfan | 15.97 | 7900959 | |
| MESH:D016757 | Death, Sudden, Cardiac | arsenic trioxide | 3.62 | 15213294 | |
| MESH:D003711 | Demyelinating Diseases | Tamoxifen | 3.86 | 19031437 | |
| MESH:D017449 | Dermatitis, Allergic Contact | 4,4'-diaminodiphenylmethane | 2.33 | 11906362 18759878 14531868 11298694 2524372 8970840 12868966 8156756 | |
| MESH:D003876 | Dermatitis, Atopic | pirinixic acid | 2.17 | 18249437 | |
| MESH:D003877 | Dermatitis, Contact | 4,4'-diaminodiphenylmethane | 3.02 | 3621924 2952479 | |
| MESH:D003922 | Diabetes Mellitus, Type 1 | Vitamin A | 3.33 | 16506275 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Diethylnitrosamine | 3.71 | 20387270 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Tetrachlorodibenzodioxin | 3.71 | 17107852 | |
| MESH:D003928 | Diabetic Nephropathies | Estradiol | 7.39 | 19279558 | |
| MESH:D003928 | Diabetic Nephropathies | Tamoxifen | 7.39 | 19279558 | |
| MESH:D003929 | Diabetic Neuropathies | Progesterone | 3.99 | 17187935 | |
| MESH:D056486 | Drug-Induced Liver Injury | 2,4-dinitrotoluene | 22.24 | 21346803 18551238 | |
| MESH:D056486 | Drug-Induced Liver Injury | 2,6-dinitrotoluene | 22.24 | 21346803 18551238 | |
| MESH:D056486 | Drug-Induced Liver Injury | 4,4'-diaminodiphenylmethane | 22.24 | 1440618 9328219 18289764 9022650 18692083 11289319 18648102 16192314 6482804 8291058 6679447 9653073 7440962 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 22.24 | 10663392 16177239 19923254 10915739 19164858 16081117 12594235 11287661 16485898 19739265 16393943 16227642 12392966 16109766 2444490 11834606 14550746 16781746 19420014 19416960 17562736 14725611 15619225 11461765 12540782 15968718 12958197 19085960 19370779 14986274 12153990 11739529 11529661 12705907 11421492 17906064 17522070 18713872 10774834 18071297 11743745 | |
| MESH:D056486 | Drug-Induced Liver Injury | Amiodarone | 22.24 | 15265979 18218290 | |
| MESH:D056486 | Drug-Induced Liver Injury | cyanoginosin LR | 22.24 | 17654400 | |
| MESH:D056486 | Drug-Induced Liver Injury | Diethylnitrosamine | 22.24 | 19107877 | |
| MESH:D056486 | Drug-Induced Liver Injury | Tetrachlorodibenzodioxin | 22.24 | 20420201 | |
| MESH:D056486 | Drug-Induced Liver Injury | Tetracycline | 22.24 | 17522070 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 3.57 | 19426721 | |
| MESH:D004362 | Drug Toxicity | Tetrachlorodibenzodioxin | 2.37 | 11462148 | |
| MESH:D015352 | Dry Eye Syndromes | Vitamin A | 5.28 | 16146918 | |
| MESH:D004417 | Dyspnea | Dichlorodiphenyl Dichloroethylene | 9.33 | 16487989 | |
| MESH:D004417 | Dyspnea | Endosulfan | 9.33 | 3388749 7900959 | |
| MESH:D004421 | Dystonia | Phenobarbital | 3.53 | 1851702 | |
| MESH:C538011 | Eales disease | Vitamin A | 5.09 | 9068938 | |
| MESH:D004480 | Ectromelia | Vitamin A | 5.29 | 16054864 | |
| MESH:D004487 | Edema | pirinixic acid | 5.03 | 12083418 | |
| MESH:D004487 | Edema | Tetrachlorodibenzodioxin | 5.03 | 12711302 11000095 | |
| MESH:D004489 | Edema, Cardiac | Tetrachlorodibenzodioxin | 10.19 | 15322242 18230668 16714409 | |
| MESH:D004489 | Edema, Cardiac | Tretinoin | 10.19 | 18230668 | |
| MESH:D004646 | Emphysema | Endosulfan | 6.03 | 7900959 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Progesterone | 7.54 | 17692515 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Tamoxifen | 7.54 | 19031437 | |
| MESH:D016889 | Endometrial Neoplasms | Estradiol | 10.39 | 19148513 11473722 18566989 | |
| MESH:D016889 | Endometrial Neoplasms | Tamoxifen | 10.39 | 16202921 19155303 20544844 17893378 | |
| MESH:D016889 | Endometrial Neoplasms | Tretinoin | 10.39 | 16569247 | |
| MESH:D004715 | Endometriosis | Progesterone | 7.43 | 16134523 | |
| MESH:D004715 | Endometriosis | Tetrachlorodibenzodioxin | 7.43 | 10568697 9294722 | |
| MESH:D019446 | Endotoxemia | Lipopolysaccharides | 3.88 | 15328337 17637181 15821434 | |
| MESH:D004831 | Epilepsies, Myoclonic | Phenobarbital | 3.60 | 3659116 | |
| MESH:D004828 | Epilepsies, Partial | Phenobarbital | 3.35 | 3922381 11558140 | |
| MESH:D004827 | Epilepsy | Phenobarbital | 2.61 | 20417680 | |
| MESH:D004832 | Epilepsy, Absence | Phenobarbital | 3.11 | 6401628 | |
| MESH:D017029 | Epilepsy, Complex Partial | Phenobarbital | 3.75 | 7750514 | |
| MESH:D004830 | Epilepsy, Tonic-Clonic | Phenobarbital | 3.50 | 3659116 | |
| MESH:D004931 | Esophageal Achalasia | Diethylnitrosamine | 4.59 | 16302075 | |
| MESH:D004938 | Esophageal Neoplasms | 4,4'-diaminodiphenylmethane | 3.94 | 3581430 | |
| MESH:D004938 | Esophageal Neoplasms | arsenic trioxide | 3.94 | 12903497 | |
| MESH:D005124 | Eye Abnormalities | Tetrachlorodibenzodioxin | 7.53 | 11564622 | |
| MESH:D005124 | Eye Abnormalities | Tretinoin | 7.53 | 9664655 16938888 | |
| MESH:D005234 | Fatty Liver | Amiodarone | 24.73 | 14986274 | |
| MESH:D005234 | Fatty Liver | arsenic trioxide | 24.73 | 15073043 | |
| MESH:D005234 | Fatty Liver | Diethylnitrosamine | 24.73 | 20387270 21071580 | |
| MESH:D005234 | Fatty Liver | pirinixic acid | 24.73 | 19236843 20131406 | |
| MESH:D005234 | Fatty Liver | Tamoxifen | 24.73 | 19224547 14986274 | |
| MESH:D005234 | Fatty Liver | Tetracycline | 24.73 | 16917069 19224547 | |
| MESH:D052776 | Female Urogenital Diseases | Tamoxifen | 2.91 | 16709447 | |
| MESH:D005313 | Fetal Death | Tetrachlorodibenzodioxin | 2.95 | 11858732 | |
| MESH:D005327 | Fetal Resorption | Vitamin A | 4.84 | 16054864 | |
| MESH:D005334 | Fever | Lipopolysaccharides | 3.57 | 9205823 11852909 | |
| MESH:D005350 | Fibroma | 4,4'-diaminodiphenylmethane | 4.49 | 6705139 | |
| MESH:D018221 | Fibromatosis, Abdominal | Tamoxifen | 4.01 | 14745880 | |
| MESH:D018222 | Fibromatosis, Aggressive | Tamoxifen | 3.66 | 19069698 | |
| MESH:D005355 | Fibrosis | Tetrachlorodibenzodioxin | 6.95 | 20067830 | |
| MESH:D005355 | Fibrosis | Tretinoin | 6.95 | 17994277 | |
| MESH:D005534 | Foot Diseases | Arsenic | 5.03 | 6392382 | |
| MESH:D005706 | Gallbladder Neoplasms | arsenic trioxide | 3.77 | 16904648 | |
| MESH:D005756 | Gastritis | Acetaminophen | 3.15 | 16983495 | |
| MESH:D005909 | Glioblastoma | Fenretinide | 6.28 | 16187019 | |
| MESH:D005909 | Glioblastoma | Tretinoin | 6.28 | 17312396 | |
| MESH:D006042 | Goiter | 4,4'-diaminodiphenylmethane | 3.56 | 7505956 | |
| MESH:D006058 | Gonadal Disorders | Tetrachlorodibenzodioxin | 4.07 | 10696789 | |
| MESH:D006258 | Head and Neck Neoplasms | Tretinoin | 2.83 | 16096774 | |
| MESH:D006317 | Hearing Loss, Noise-Induced | Tretinoin | 4.63 | 16084493 | |
| MESH:D006330 | Heart Defects, Congenital | Tetrachlorodibenzodioxin | 9.55 | 10048152 11294989 | |
| MESH:D006330 | Heart Defects, Congenital | Tretinoin | 9.55 | 9664655 14991402 | |
| MESH:D006330 | Heart Defects, Congenital | Vitamin A | 9.55 | 16080930 10992263 | |
| MESH:D006333 | Heart Failure | pirinixic acid | 2.21 | 20558911 | |
| MESH:D006463 | Hemolytic-Uremic Syndrome | Lipopolysaccharides | 3.93 | 16366002 | |
| MESH:D006470 | Hemorrhage | Endosulfan | 8.90 | 7900959 | |
| MESH:D006470 | Hemorrhage | Tetrachlorodibenzodioxin | 8.90 | 11000095 | |
| MESH:D006505 | Hepatitis | 4,4'-diaminodiphenylmethane | 8.13 | 6705139 | |
| MESH:D006505 | Hepatitis | Dichlorodiphenyl Dichloroethylene | 8.13 | 16487989 | |
| MESH:D006529 | Hepatomegaly | Amiodarone | 21.80 | 15265979 | |
| MESH:D006529 | Hepatomegaly | Phenobarbital | 21.80 | 16109766 | |
| MESH:D006529 | Hepatomegaly | pirinixic acid | 21.80 | 19176532 16221962 19772884 18467677 | |
| MESH:D006529 | Hepatomegaly | Tetrachlorodibenzodioxin | 21.80 | 15340226 16120746 12621046 | |
| MESH:D006529 | Hepatomegaly | triadimefon | 21.80 | 17178688 17178689 | |
| MESH:D006548 | Hernia, Diaphragmatic | Vitamin A | 3.42 | 16292552 16863852 17436238 15707848 16877224 16490937 | |
| MESH:D006558 | Herpes Genitalis | Estradiol | 4.50 | 15709030 | |
| MESH:D015658 | HIV Infections | beta Carotene | 6.31 | 16960176 | |
| MESH:D015658 | HIV Infections | Vitamin A | 6.31 | 16960176 | |
| MESH:D006679 | HIV Seropositivity | Vitamin A | 5.08 | 17209195 | |
| MESH:D019584 | Hot Flashes | Estradiol | 3.23 | 17088409 | |
| MESH:D006869 | Hydronephrosis | Tetrachlorodibenzodioxin | 3.52 | 8697196 18606429 15340226 16354765 16959395 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 6.26 | 16870215 | |
| MESH:D006930 | Hyperalgesia | Tretinoin | 6.26 | 16870215 | |
| MESH:D006937 | Hypercholesterolemia | Amiodarone | 3.41 | 9751232 8137927 | |
| MESH:D017681 | Hypereosinophilic Syndrome | Tretinoin | 4.06 | 16778211 | |
| MESH:D006943 | Hyperglycemia | pirinixic acid | 2.73 | 20558911 | |
| MESH:D017488 | Hyperkeratosis, Epidermolytic | Arsenic | 4.00 | 17050553 | |
| MESH:D006965 | Hyperplasia | 4,4'-diaminodiphenylmethane | 3.43 | 15034207 | |
| MESH:D006973 | Hypertension | Arsenic | 4.49 | 16076760 11953799 9931084 | |
| MESH:D006973 | Hypertension | Tetrachlorodibenzodioxin | 4.49 | 18850075 18670907 | |
| MESH:D006986 | Hypervitaminosis A | Vitamin A | 5.64 | 16054864 | |
| MESH:D006987 | Hypesthesia | Arsenic | 5.03 | 16093927 | |
| MESH:D007037 | Hypothyroidism | Amiodarone | 4.01 | 17991464 18020914 | |
| MESH:D020244 | Infarction, Middle Cerebral Artery | Progesterone | 3.90 | 15869954 | |
| MESH:D007247 | Infertility, Female | Dieldrin | 4.46 | 10630421 | |
| MESH:D007248 | Infertility, Male | Chlordan | 9.80 | 9432128 | |
| MESH:D007248 | Infertility, Male | Dichlorodiphenyl Dichloroethylene | 9.80 | 17192596 12948891 | |
| MESH:D007248 | Infertility, Male | Endosulfan | 9.80 | 9432128 8588293 | |
| MESH:D007249 | Inflammation | Diethylnitrosamine | 12.77 | 18785209 | |
| MESH:D007249 | Inflammation | Lipopolysaccharides | 12.77 | 17237260 17963957 12878042 17255318 9205823 | |
| MESH:D007249 | Inflammation | Progesterone | 12.77 | 15869954 | |
| MESH:D007249 | Inflammation | Tamoxifen | 12.77 | 19457130 | |
| MESH:D007249 | Inflammation | Tetrachlorodibenzodioxin | 12.77 | 12200463 12878042 | |
| MESH:D007333 | Insulin Resistance | Estradiol | 6.03 | 16393666 16627594 | |
| MESH:D007333 | Insulin Resistance | pirinixic acid | 6.03 | 16306350 | |
| MESH:D007410 | Intestinal Diseases | Tretinoin | 3.26 | 17994277 | |
| MESH:D019586 | Intracranial Hypertension | Vitamin A | 5.29 | 15955940 | |
| MESH:D019189 | Iron Metabolism Disorders | Lipopolysaccharides | 4.15 | 17255318 | |
| MESH:D007565 | Jaundice | 4,4'-diaminodiphenylmethane | 4.49 | 8074119 9022650 | |
| MESH:D007569 | Jaw Abnormalities | Tetrachlorodibenzodioxin | 14.57 | 16580747 | |
| MESH:D007569 | Jaw Abnormalities | Tretinoin | 14.57 | 15992940 17551590 | |
| MESH:D007569 | Jaw Abnormalities | triadimefon | 14.57 | 15992940 15834900 | |
| MESH:D007642 | Keratosis | Arsenic | 4.47 | 16930632 12749816 | |
| MESH:D017492 | Keratosis, Seborrheic | alitretinoin | 5.12 | 16144296 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 4.84 | 12587719 15629191 | |
| MESH:D007674 | Kidney Diseases | Estradiol | 4.84 | 15618244 | |
| MESH:D007680 | Kidney Neoplasms | 2,4-dinitrotoluene | 18.86 | 16705839 | |
| MESH:D007680 | Kidney Neoplasms | 2,6-dinitrotoluene | 18.86 | 16705839 | |
| MESH:D007680 | Kidney Neoplasms | 4,4'-diaminodiphenylmethane | 18.86 | 6582329 | |
| MESH:D007680 | Kidney Neoplasms | Estradiol | 18.86 | 15610895 | |
| MESH:D007680 | Kidney Neoplasms | Tamoxifen | 18.86 | 18625569 | |
| MESH:D007859 | Learning Disorders | Endosulfan | 4.60 | 8157075 | |
| MESH:D007938 | Leukemia | arsenic trioxide | 5.41 | 15070760 | |
| MESH:D007938 | Leukemia | Tretinoin | 5.41 | 17143497 | |
| MESH:D015459 | Leukemia-Lymphoma, Adult T-Cell | arsenic trioxide | 3.33 | 17077332 12560223 | |
| MESH:D007948 | Leukemia, Monocytic, Acute | arsenic trioxide | 3.79 | 16972261 | |
| MESH:D015464 | Leukemia, Myelogenous, Chronic, BCR-ABL Positive | arsenic trioxide | 3.04 | 14633726 | |
| MESH:D007951 | Leukemia, Myeloid | arsenic trioxide | 7.93 | 19077051 | |
| MESH:D007951 | Leukemia, Myeloid | Tretinoin | 7.93 | 16482212 19285840 16932348 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | arsenic trioxide | 3.49 | 19850784 17050201 16467208 20471514 16968895 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | Tretinoin | 3.49 | 17596541 16294345 19850784 | |
| MESH:D015473 | Leukemia, Promyelocytic, Acute | Arsenic | 10.74 | 17339181 | |
| MESH:D015473 | Leukemia, Promyelocytic, Acute | arsenic trioxide | 10.74 | 16823087 16966277 12679006 12018890 15622746 16331271 17869043 11468182 19035177 17217047 9834237 16330433 17712046 19642359 12712474 15336539 17649720 19225113 15213294 17107899 19075265 16112521 16891316 15748426 11161223 | |
| MESH:D015473 | Leukemia, Promyelocytic, Acute | Tretinoin | 10.74 | 19035177 17217047 17339181 17506722 17107899 16331271 16788101 9834237 16891316 16140955 17361223 16766008 19075265 17368321 19642359 15748426 16823087 12679006 16935935 17712046 17301526 17294898 19225113 17649720 19029980 | |
| MESH:D015458 | Leukemia, T-Cell | arsenic trioxide | 3.86 | 16882451 | |
| MESH:D007970 | Leukopenia | Lipopolysaccharides | 4.18 | 15821434 | |
| MESH:D007972 | Leukoplakia, Oral | Fenretinide | 5.52 | 16707609 | |
| MESH:D017880 | Limb Deformities, Congenital | Dichlorodiphenyl Dichloroethylene | 11.75 | 12745335 | |
| MESH:D017880 | Limb Deformities, Congenital | Tretinoin | 11.75 | 9224671 | |
| MESH:D017880 | Limb Deformities, Congenital | Vitamin A | 11.75 | 16054864 | |
| MESH:D008064 | Lipidoses | Amiodarone | 6.65 | 17567588 15342952 | |
| MESH:D008064 | Lipidoses | Tamoxifen | 6.65 | 15342952 17567588 | |
| MESH:D008103 | Liver Cirrhosis | Diethylnitrosamine | 9.39 | 19638242 20032147 18665156 18522880 18407596 | |
| MESH:D008103 | Liver Cirrhosis | Phenobarbital | 9.39 | 21047994 | |
| MESH:D008103 | Liver Cirrhosis | Vitamin A | 9.39 | 16256175 | |
| MESH:D008105 | Liver Cirrhosis, Biliary | 4,4'-diaminodiphenylmethane | 2.86 | 9327722 15034207 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Estradiol | 11.73 | 14716833 14659978 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Lipopolysaccharides | 11.73 | 12878042 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | pirinixic acid | 11.73 | 15474484 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Retinaldehyde | 11.73 | 16248980 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Tamoxifen | 11.73 | 18564211 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Tetrachlorodibenzodioxin | 11.73 | 12878042 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Tretinoin | 11.73 | 18397230 16248980 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Vitamin A | 11.73 | 16248980 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 13.73 | 19014921 16611625 19460945 12587719 12969438 19784758 11587558 16610002 | |
| MESH:D008107 | Liver Diseases | Arsenic | 13.73 | 11134558 | |
| MESH:D008107 | Liver Diseases | Diethylnitrosamine | 13.73 | 17034775 | |
| MESH:D008107 | Liver Diseases | Phenobarbital | 13.73 | 19363144 | |
| MESH:D008107 | Liver Diseases | triadimefon | 13.73 | 19363144 | |
| MESH:D008107 | Liver Diseases | Vitamin A | 13.73 | 16175620 | |
| MESH:D008108 | Liver Diseases, Alcoholic | Vitamin A | 4.65 | 16762690 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 2.79 | 16871587 17185352 | |
| MESH:D008113 | Liver Neoplasms | 2,6-dinitrotoluene | 41.57 | 7678174 | |
| MESH:D008113 | Liver Neoplasms | Arsenic | 41.57 | 16368122 | |
| MESH:D008113 | Liver Neoplasms | arsenic trioxide | 41.57 | 14682389 | |
| MESH:D008113 | Liver Neoplasms | beta-Naphthoflavone | 41.57 | 21295105 19389873 | |
| MESH:D008113 | Liver Neoplasms | Chlordan | 41.57 | 2422723 | |
| MESH:D008113 | Liver Neoplasms | ciprofibrate | 41.57 | 12771043 | |
| MESH:D008113 | Liver Neoplasms | Dieldrin | 41.57 | 9539021 8742319 | |
| MESH:D008113 | Liver Neoplasms | Diethylnitrosamine | 41.57 | 19427195 19090486 21278145 10737359 12771043 20492335 16942905 20405173 15175105 2422723 19638242 21047994 18644402 18978307 12112319 20118626 19812893 21167192 18648771 21071580 20137499 19642983 18754104 19256749 19426721 19073162 20101389 19833225 18977376 20501860 19499222 9163691 19294768 19551842 20452335 2862719 19690152 20434301 19254457 20583210 19255062 15885732 19850985 19996281 | |
| MESH:D008113 | Liver Neoplasms | Phenobarbital | 41.57 | 19812893 15975961 21047994 19073162 19482888 8742319 | |
| MESH:D008113 | Liver Neoplasms | pirinixic acid | 41.57 | 20007298 16377806 15890375 | |
| MESH:D008113 | Liver Neoplasms | Tamoxifen | 41.57 | 16684651 | |
| MESH:D008113 | Liver Neoplasms | Tetrachlorodibenzodioxin | 41.57 | 16984957 | |
| MESH:D008113 | Liver Neoplasms | triadimefon | 41.57 | 19028983 | |
| MESH:D008114 | Liver Neoplasms, Experimental | 2,6-dinitrotoluene | 36.30 | 2876786 6135515 2876784 | |
| MESH:D008114 | Liver Neoplasms, Experimental | 4,4'-diaminodiphenylmethane | 36.30 | 1399818 598648 3712494 6587162 | |
| MESH:D008114 | Liver Neoplasms, Experimental | arsenic trioxide | 36.30 | 20377131 | |
| MESH:D008114 | Liver Neoplasms, Experimental | beta Carotene | 36.30 | 17113696 | |
| MESH:D008114 | Liver Neoplasms, Experimental | beta-Naphthoflavone | 36.30 | 18164116 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Diethylnitrosamine | 36.30 | 19004024 19009564 16842330 18164116 17942915 18079962 3124819 18253720 18308698 18544905 19519916 19126423 17174075 18775883 2563599 16267830 18093689 17854601 9362446 21159647 18282651 19539802 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Phenobarbital | 36.30 | 17172636 1399818 18308698 2563599 6150874 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Tetrachlorodibenzodioxin | 36.30 | 12151625 | |
| MESH:D008114 | Liver Neoplasms, Experimental | triadimefon | 36.30 | 17178689 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Vitamin A | 36.30 | 17113696 | |
| MESH:D008133 | Long QT Syndrome | Amiodarone | 6.87 | 15350150 11989578 17391786 | |
| MESH:D008133 | Long QT Syndrome | arsenic trioxide | 6.87 | 15213294 | |
| MESH:D008171 | Lung Diseases | Amiodarone | 6.66 | 12587719 | |
| MESH:D008171 | Lung Diseases | Vitamin A | 6.66 | 16863852 | |
| MESH:D017563 | Lung Diseases, Interstitial | Amiodarone | 3.95 | 18516814 | |
| MESH:D055370 | Lung Injury | Lipopolysaccharides | 3.51 | 21114838 | |
| MESH:D008175 | Lung Neoplasms | alitretinoin | 13.71 | 16413115 | |
| MESH:D008175 | Lung Neoplasms | Arsenic | 13.71 | 19168569 17306315 17976673 | |
| MESH:D008175 | Lung Neoplasms | arsenic trioxide | 13.71 | 11798837 19825857 | |
| MESH:D008175 | Lung Neoplasms | beta Carotene | 13.71 | 16401635 | |
| MESH:D008175 | Lung Neoplasms | bexarotene | 13.71 | 17849452 | |
| MESH:D008175 | Lung Neoplasms | Diethylnitrosamine | 13.71 | 20970405 20512841 6695378 21163286 | |
| MESH:D008175 | Lung Neoplasms | Isotretinoin | 13.71 | 15899809 | |
| MESH:D008175 | Lung Neoplasms | Tamoxifen | 13.71 | 18625569 | |
| MESH:D008175 | Lung Neoplasms | Tetrachlorodibenzodioxin | 13.71 | 11884234 19555203 | |
| MESH:D016410 | Lymphoma, T-Cell, Cutaneous | bexarotene | 4.64 | 11161223 | |
| MESH:D015674 | Mammary Neoplasms, Animal | Tamoxifen | 3.25 | 19428831 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | bexarotene | 15.17 | 19196723 15591091 19196722 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Estradiol | 15.17 | 17203775 11807958 11408345 16891317 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Fenretinide | 15.17 | 10697514 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Progesterone | 15.17 | 11408345 17203775 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Tamoxifen | 15.17 | 14580682 19196722 11731420 19196723 16827153 | |
| MESH:D020149 | Manganese Poisoning | Estradiol | 10.89 | 19453300 | |
| MESH:D020149 | Manganese Poisoning | Tamoxifen | 10.89 | 19453300 | |
| MESH:D008527 | Medulloblastoma | Tretinoin | 2.56 | 17453147 | |
| MESH:D008545 | Melanoma | Fenretinide | 6.41 | 16270382 | |
| MESH:D008545 | Melanoma | Isotretinoin | 6.41 | 17237267 | |
| MESH:D008545 | Melanoma | Tamoxifen | 6.41 | 19393235 12393984 | |
| MESH:D008545 | Melanoma | Tretinoin | 6.41 | 16752155 | |
| MESH:D018328 | Melanoma, Amelanotic | Tamoxifen | 3.66 | 15990972 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 3.06 | 19513568 | |
| MESH:D008591 | Meningomyelocele | Tretinoin | 3.92 | 16940565 | |
| MESH:D009062 | Mouth Neoplasms | Fenretinide | 3.92 | 16274795 | |
| MESH:D009101 | Multiple Myeloma | arsenic trioxide | 6.38 | 19549372 19417148 11468182 15949261 14977855 | |
| MESH:D009101 | Multiple Myeloma | Vitamin A | 6.38 | 16374440 | |
| MESH:D009135 | Muscular Diseases | pirinixic acid | 3.00 | 16239165 | |
| MESH:D009181 | Mycoses | Amiodarone | 4.37 | 17974566 12754197 | |
| MESH:D009182 | Mycosis Fungoides | arsenic trioxide | 4.14 | 18349030 | |
| MESH:D009190 | Myelodysplastic Syndromes | arsenic trioxide | 6.34 | 16105982 16882451 | |
| MESH:D009190 | Myelodysplastic Syndromes | Tretinoin | 6.34 | 17596541 | |
| MESH:D009203 | Myocardial Infarction | pirinixic acid | 1.91 | 19151258 | |
| MESH:D017202 | Myocardial Ischemia | Arsenic | 7.63 | 15371236 | |
| MESH:D017202 | Myocardial Ischemia | Tetrachlorodibenzodioxin | 7.63 | 12213967 | |
| MESH:D015428 | Myocardial Reperfusion Injury | Estradiol | 6.91 | 16810080 | |
| MESH:D015428 | Myocardial Reperfusion Injury | pirinixic acid | 6.91 | 16411023 | |
| MESH:D020191 | Myoclonic Epilepsies, Progressive | Phenobarbital | 3.96 | 17484760 | |
| MESH:D009336 | Necrosis | 2,4-dinitrotoluene | 8.63 | 18551238 | |
| MESH:D009336 | Necrosis | 2,6-dinitrotoluene | 8.63 | 7678174 18551238 | |
| MESH:D009361 | Neoplasm Invasiveness | arsenic trioxide | 3.47 | 16624393 | |
| MESH:D009362 | Neoplasm Metastasis | 4,4'-diaminodiphenylmethane | 8.09 | 3581430 | |
| MESH:D009362 | Neoplasm Metastasis | Diethylnitrosamine | 8.09 | 3581430 9029167 | |
| MESH:D009362 | Neoplasm Metastasis | Tamoxifen | 8.09 | 19393235 | |
| MESH:D009364 | Neoplasm Recurrence, Local | Tamoxifen | 2.33 | 19410462 | |
| MESH:D009369 | Neoplasms | alitretinoin | 16.18 | 16946489 | |
| MESH:D009369 | Neoplasms | beta Carotene | 16.18 | 17051425 | |
| MESH:D009369 | Neoplasms | Dieldrin | 16.18 | 8820588 | |
| MESH:D009369 | Neoplasms | Fenretinide | 16.18 | 15958647 17353921 | |
| MESH:D009369 | Neoplasms | pirinixic acid | 16.18 | 17405874 | |
| MESH:D009369 | Neoplasms | Tretinoin | 16.18 | 16946489 16594593 | |
| MESH:D009376 | Neoplasms, Hormone-Dependent | bexarotene | 9.18 | 19196722 | |
| MESH:D009376 | Neoplasms, Hormone-Dependent | Tamoxifen | 9.18 | 19196722 19189210 19200415 | |
| MESH:D009389 | Neovascularization, Pathologic | Estradiol | 3.22 | 17289903 | |
| MESH:D009395 | Nephritis, Interstitial | Tetracycline | 4.26 | 9884423 | |
| MESH:D009421 | Nervous System Malformations | Estradiol | 13.49 | 16427766 11399458 | |
| MESH:D009421 | Nervous System Malformations | Tetrachlorodibenzodioxin | 13.49 | 14600291 | |
| MESH:D009421 | Nervous System Malformations | Tretinoin | 13.49 | 9125849 | |
| MESH:D009436 | Neural Tube Defects | 4,4'-diaminodiphenylmethane | 19.06 | 6679447 | |
| MESH:D009436 | Neural Tube Defects | Arsenic | 19.06 | 16620997 | |
| MESH:D009436 | Neural Tube Defects | arsenic trioxide | 19.06 | 10525206 | |
| MESH:D009436 | Neural Tube Defects | Tretinoin | 19.06 | 9142499 | |
| MESH:D009436 | Neural Tube Defects | Vitamin A | 19.06 | 17400914 | |
| MESH:D009447 | Neuroblastoma | Isotretinoin | 3.76 | 17368321 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 6.77 | 18514411 | |
| MESH:D019636 | Neurodegenerative Diseases | Diethylnitrosamine | 6.77 | 20387270 | |
| MESH:D020078 | Neurogenic Inflammation | Arsenic | 3.90 | 17056641 | |
| MESH:D009461 | Neurologic Manifestations | Diethylnitrosamine | 4.59 | 20387270 | |
| MESH:D009472 | Neuronal Ceroid-Lipofuscinoses | Fenretinide | 5.16 | 16303764 | |
| MESH:D009765 | Obesity | pirinixic acid | 1.67 | 20558911 | |
| MESH:D009784 | Occupational Diseases | 2,4-dinitrotoluene | 12.46 | 16049721 12819281 | |
| MESH:D009784 | Occupational Diseases | 2,6-dinitrotoluene | 12.46 | 16049721 | |
| MESH:D009784 | Occupational Diseases | 4,4'-diaminodiphenylmethane | 12.46 | 4026338 6482804 | |
| MESH:D009902 | Optic Neuritis | 4,4'-diaminodiphenylmethane | 4.49 | 3988306 | |
| MESH:D010018 | Osteomalacia | Phenobarbital | 3.85 | 17016548 | |
| MESH:D010051 | Ovarian Neoplasms | Arsenic | 16.36 | 17306315 | |
| MESH:D010051 | Ovarian Neoplasms | arsenic trioxide | 16.36 | 12452020 19769630 16624393 | |
| MESH:D010051 | Ovarian Neoplasms | Estradiol | 16.36 | 19401270 | |
| MESH:D010051 | Ovarian Neoplasms | Fenretinide | 16.36 | 16133793 | |
| MESH:D010051 | Ovarian Neoplasms | Progesterone | 16.36 | 17393432 16525653 | |
| MESH:D010051 | Ovarian Neoplasms | Tretinoin | 16.36 | 16936753 | |
| MESH:D010146 | Pain | Acetaminophen | 5.21 | 16870215 | |
| MESH:D010146 | Pain | Tretinoin | 5.21 | 16870215 | |
| MESH:D010190 | Pancreatic Neoplasms | arsenic trioxide | 14.04 | 15580305 | |
| MESH:D010190 | Pancreatic Neoplasms | Diethylnitrosamine | 14.04 | 16540662 | |
| MESH:D010190 | Pancreatic Neoplasms | Fenretinide | 14.04 | 15580305 | |
| MESH:D010190 | Pancreatic Neoplasms | Phenobarbital | 14.04 | 16965848 | |
| MESH:D010190 | Pancreatic Neoplasms | Tretinoin | 14.04 | 15976015 | |
| MESH:D010212 | Papilloma | 4,4'-diaminodiphenylmethane | 2.98 | 7296757 | |
| MESH:D010235 | Paraganglioma | arsenic trioxide | 3.68 | 19927285 | |
| MESH:D010300 | Parkinson Disease | Dieldrin | 3.32 | 11445065 17291500 11181820 16809432 16112328 | |
| MESH:D010382 | Peliosis Hepatis | Tetrachlorodibenzodioxin | 3.72 | 12520081 | |
| MESH:D010391 | Pemphigoid, Bullous | Tetracycline | 4.90 | 11026799 | |
| MESH:D010523 | Peripheral Nervous System Diseases | Arsenic | 3.69 | 16093927 | |
| MESH:D016491 | Peripheral Vascular Diseases | Arsenic | 4.47 | 6392382 15371236 16905509 | |
| MESH:D010787 | Photosensitivity Disorders | 4,4'-diaminodiphenylmethane | 3.94 | 6228378 | |
| MESH:D011014 | Pneumonia | Lipopolysaccharides | 4.04 | 11605937 12224865 | |
| MESH:D017499 | Porokeratosis | alitretinoin | 5.47 | 16144296 | |
| MESH:D017119 | Porphyria Cutanea Tarda | Tetrachlorodibenzodioxin | 3.07 | 18163543 | |
| MESH:D011230 | Precancerous Conditions | Diethylnitrosamine | 7.64 | 2563599 | |
| MESH:D011230 | Precancerous Conditions | Phenobarbital | 7.64 | 2563599 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | Isotretinoin | 8.13 | 18769834 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | Tetrachlorodibenzodioxin | 8.13 | 11118676 11896295 11399792 11222880 | |
| MESH:D017096 | Prion Diseases | Tetracycline | 4.89 | 10903871 | |
| MESH:D019048 | Prostatic Intraepithelial Neoplasia | Estradiol | 3.42 | 20887781 | |
| MESH:D011471 | Prostatic Neoplasms | Arsenic | 1.88 | 16140617 | |
| MESH:D011471 | Prostatic Neoplasms | arsenic trioxide | 1.88 | 19131511 | |
| MESH:D011471 | Prostatic Neoplasms | Cholecalciferol | 1.88 | 17024972 | |
| MESH:D011471 | Prostatic Neoplasms | Estradiol | 1.88 | 16740699 | |
| MESH:D011471 | Prostatic Neoplasms | Fenretinide | 1.88 | 17024972 | |
| MESH:D011471 | Prostatic Neoplasms | Tamoxifen | 1.88 | 15067354 | |
| MESH:D011507 | Proteinuria | Arsenic | 7.69 | 21343184 | |
| MESH:D011507 | Proteinuria | Tretinoin | 7.69 | 16636307 | |
| MESH:D019310 | Pseudolymphoma | Phenobarbital | 3.97 | 12752131 | |
| MESH:D011596 | Psychomotor Disorders | Isotretinoin | 5.40 | 18769834 | |
| MESH:D011625 | Pterygium | Tretinoin | 4.27 | 16723453 | |
| MESH:D011658 | Pulmonary Fibrosis | Amiodarone | 2.64 | 12832656 12490602 11597910 | |
| MESH:D015427 | Reperfusion Injury | pirinixic acid | 2.11 | 19058328 | |
| MESH:D012127 | Respiratory Distress Syndrome, Newborn | Vitamin A | 5.28 | 16877224 | |
| MESH:D012130 | Respiratory Hypersensitivity | Lipopolysaccharides | 3.38 | 10835634 | |
| MESH:D015619 | Respiratory System Abnormalities | Tetrachlorodibenzodioxin | 3.34 | 18990726 | |
| MESH:D012162 | Retinal Degeneration | 4,4'-diaminodiphenylmethane | 7.80 | 3692021 | |
| MESH:D012162 | Retinal Degeneration | Fenretinide | 7.80 | 16303925 | |
| MESH:D012208 | Rhabdomyosarcoma | Tretinoin | 3.62 | 16116481 16283617 | |
| MESH:D012468 | Salivary Gland Neoplasms | Progesterone | 2.65 | 18045962 | |
| MESH:D012512 | Sarcoma, Ewing's | arsenic trioxide | 3.47 | 16646077 | |
| MESH:D012640 | Seizures | 2,4-dinitrotoluene | 11.16 | 18551238 | |
| MESH:D012640 | Seizures | 2,6-dinitrotoluene | 11.16 | 18551238 | |
| MESH:D012640 | Seizures | Endosulfan | 11.16 | 7539098 10698677 | |
| MESH:D012640 | Seizures | Phenobarbital | 11.16 | 3137016 4039156 11442880 16876388 | |
| MESH:D003294 | Seizures, Febrile | Phenobarbital | 4.30 | 6407741 | |
| OMIM:609620 | SHORT QT SYNDROME 1 | Amiodarone | 4.56 | 18724381 | |
| MESH:D012871 | Skin Diseases | Arsenic | 4.83 | 17050553 17548696 17938729 19834688 16353154 18709164 15952646 6392382 16702368 16759981 17453740 | |
| MESH:D012871 | Skin Diseases | Vitamin A | 4.83 | 18709164 | |
| MESH:D012878 | Skin Neoplasms | Arsenic | 11.40 | 15504454 17029826 19538983 17976673 16251483 17050553 | |
| MESH:D012878 | Skin Neoplasms | Fenretinide | 11.40 | 16467112 | |
| MESH:D012878 | Skin Neoplasms | Tetrachlorodibenzodioxin | 11.40 | 16192470 | |
| MESH:D012878 | Skin Neoplasms | Tretinoin | 11.40 | 16467112 | |
| MESH:D013088 | Spermatocele | Tamoxifen | 3.76 | 16709447 | |
| MESH:D013119 | Spinal Cord Injuries | Progesterone | 9.15 | 15862959 16503802 | |
| MESH:D013119 | Spinal Cord Injuries | Tamoxifen | 9.15 | 19457130 | |
| MESH:D013272 | Stomach Diseases | beta Carotene | 4.58 | 17638125 | |
| MESH:D013274 | Stomach Neoplasms | arsenic trioxide | 3.02 | 17007042 | |
| MESH:D013274 | Stomach Neoplasms | Diethylnitrosamine | 3.02 | 18456281 | |
| MESH:D013274 | Stomach Neoplasms | Tretinoin | 3.02 | 17261132 | |
| MESH:D013276 | Stomach Ulcer | Amiodarone | 6.24 | 18087811 | |
| MESH:D013276 | Stomach Ulcer | beta Carotene | 6.24 | 12500499 | |
| MESH:D013610 | Tachycardia | Amiodarone | 3.80 | 11238279 | |
| MESH:D017180 | Tachycardia, Ventricular | Amiodarone | 3.70 | 19225199 | |
| MESH:D013921 | Thrombocytopenia | Lipopolysaccharides | 3.71 | 15821434 | |
| MESH:D013959 | Thyroid Diseases | Amiodarone | 10.29 | 19731979 | |
| MESH:D013959 | Thyroid Diseases | Tetrachlorodibenzodioxin | 10.29 | 12697716 | |
| MESH:D013964 | Thyroid Neoplasms | 4,4'-diaminodiphenylmethane | 22.88 | 3712494 6582329 1399818 7505956 6587162 | |
| MESH:D013964 | Thyroid Neoplasms | arsenic trioxide | 22.88 | 19014326 | |
| MESH:D013964 | Thyroid Neoplasms | Diethylnitrosamine | 22.88 | 7505956 | |
| MESH:D013964 | Thyroid Neoplasms | Phenobarbital | 22.88 | 1399818 | |
| MESH:D013964 | Thyroid Neoplasms | Tretinoin | 22.88 | 16026305 17045167 | |
| MESH:D013964 | Thyroid Neoplasms | triadimefon | 22.88 | 17178689 | |
| MESH:D013971 | Thyrotoxicosis | Amiodarone | 4.35 | 19584973 18020914 | |
| MESH:D013978 | Tibial Fractures | Estradiol | 4.16 | 19048282 | |
| MESH:D014062 | Tongue Neoplasms | Tretinoin | 3.34 | 16051514 | |
| MESH:D016171 | Torsades de Pointes | Amiodarone | 8.54 | 17467628 11989578 | |
| MESH:D016171 | Torsades de Pointes | arsenic trioxide | 8.54 | 15213294 | |
| MESH:D014376 | Tuberculosis | Tretinoin | 2.89 | 16040207 | |
| MESH:D001749 | Urinary Bladder Neoplasms | 2,4-dinitrotoluene | 20.60 | 16049721 | |
| MESH:D001749 | Urinary Bladder Neoplasms | 2,6-dinitrotoluene | 20.60 | 16049721 | |
| MESH:D001749 | Urinary Bladder Neoplasms | 4,4'-diaminodiphenylmethane | 20.60 | 8074119 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Arsenic | 20.60 | 17976673 19429237 15987713 18640142 19322015 17306315 11144890 | |
| MESH:D001749 | Urinary Bladder Neoplasms | arsenic trioxide | 20.60 | 20435036 12845720 11780464 12973940 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Fenretinide | 20.60 | 16720286 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Tamoxifen | 20.60 | 16712894 8653321 17572228 | |
| MESH:D014570 | Urologic Diseases | Dichlorodiphenyl Dichloroethylene | 5.21 | 16487989 | |
| MESH:D014571 | Urologic Neoplasms | 2,4-dinitrotoluene | 10.26 | 10091137 | |
| MESH:D014571 | Urologic Neoplasms | 2,6-dinitrotoluene | 10.26 | 10091137 | |
| MESH:D014581 | Urticaria | Acetaminophen | 2.50 | 10982225 | |
| MESH:D002583 | Uterine Cervical Neoplasms | Fenretinide | 8.21 | 16154183 | |
| MESH:D002583 | Uterine Cervical Neoplasms | Tretinoin | 8.21 | 16129372 | |
| MESH:D014604 | Uveal Neoplasms | Tretinoin | 4.08 | 16752155 | |
| MESH:D014652 | Vascular Diseases | Arsenic | 4.22 | 17056641 | |
| MESH:D054079 | Vascular Malformations | Tetrachlorodibenzodioxin | 4.07 | 12125929 | |
| MESH:D014802 | Vitamin A Deficiency | Vitamin A | 4.80 | 16146918 16175781 16960172 | |
| MESH:D014820 | Vitiligo | Tretinoin | 3.56 | 16761959 | |
| MESH:D019282 | Wasting Syndrome | Tetrachlorodibenzodioxin | 3.72 | 15886252 | |
| MESH:D009396 | Wilms Tumor | Tretinoin | 3.53 | 16287080 |
| Pathway ID | Pathway Name |
|---|---|
| REACT:13433 | Biological oxidations |
| KEGG:00830 | Retinol metabolism |
| No data |
| Drugbank ID | Action | Drug Name | Description |
|---|---|---|---|
| DB00162 | inducer | Z-Mass Pm Vitamin and Mineral Supplement | Essential Vitamin;Anti-acne Agents;Vitamins (Vitamin A);Vitamins |
| DB00459 | substrate | Acitretin | Keratolytic Agents |
| DB00926 | substrate | Etretinate | Keratolytic Agents |
| DB01026 | inhibitor | Ketoconazole | Antifungals;Antifungal Agents |
| No data |
| No data |