AutismKB 2.0

Annotation Detail for SLC5A12


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Basic Information Top
Gene Symbol:SLC5A12 ( DKFZp564G223,MGC52019,SMCT2 )
Gene Full Name: solute carrier family 5 (sodium/glucose cotransporter), member 12
Band: 11p14.2
Quick LinksEntrez ID:159963; OMIM: 612455; Uniprot ID:SC5AC_HUMAN; ENSEMBL ID: ENSG00000148942; HGNC ID: 28750
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
C006632 arsenic trioxide arsenic trioxide results in increased expression of SLC5A12 mRNAincreases expression 15761015
D004281 Docosahexaenoic Acids PPARA protein promotes the reaction [Docosahexaenoic Acids results in decreased expression of SLC5A12 mRNA]decreases expression|increases reaction 18489776
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma arsenic trioxide 2.3719825857 11798837
MESH:D001321 Autistic Disorder Docosahexaenoic Acids 3.1718582451
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 4.2216206674
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.9411589617
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 1.9915073043 16217749 11135700 15553829 14691202
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.9419014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.6312490120
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8720501625
MESH:D023903 Coronary Restenosis arsenic trioxide 4.8612609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 1.9010525206
MESH:D003550 Cystic Fibrosis Docosahexaenoic Acids 5.1819747007
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.7015213294
MESH:D004938 Esophageal Neoplasms arsenic trioxide 2.4012903497
MESH:D005234 Fatty Liver arsenic trioxide 3.8415073043
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.9416904648
MESH:D007938 Leukemia arsenic trioxide 3.0315070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 11.9517077332 12560223
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Docosahexaenoic Acids 11.9517077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 5.1916972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.7914633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 4.3119077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1917050201 19850784 20471514 16467208 16968895
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.5119075265 16966277 15336539 15622746 19642359 17217047 16112521 17649720 15748426 17869043 11468182 16823087 12712474 12679006 9834237 11161223 16331271 19225113 17712046 12018890 15213294 16891316 16330433 17107899 19035177
MESH:D015458 Leukemia, T-Cell arsenic trioxide 5.0316882451
MESH:D008107 Liver Diseases Docosahexaenoic Acids 3.4917056761
MESH:D008113 Liver Neoplasms arsenic trioxide 2.4814682389
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 3.0120377131
MESH:D008133 Long QT Syndrome arsenic trioxide 3.7315213294
MESH:D008175 Lung Neoplasms arsenic trioxide 1.8719825857 11798837
MESH:D009101 Multiple Myeloma arsenic trioxide 3.4415949261 19549372 14977855 19417148 11468182
MESH:D009182 Mycosis Fungoides arsenic trioxide 5.7418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.3816105982 16882451
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.6316624393
MESH:D009436 Neural Tube Defects arsenic trioxide 3.4110525206
MESH:D010051 Ovarian Neoplasms arsenic trioxide 2.5212452020 19769630 16624393
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.6615580305
MESH:D010235 Paraganglioma arsenic trioxide 4.7719927285
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.2019131511
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.6316646077
MESH:D013274 Stomach Neoplasms arsenic trioxide 3.0117007042
MESH:D013274 Stomach Neoplasms Docosahexaenoic Acids 3.0119015929
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.4719014326
MESH:D016171 Torsades de Pointes arsenic trioxide 4.8515213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 2.6211780464 20435036 12845720 12973940
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018