AutismKB 2.0

Annotation Detail for REM2


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Basic Information Top
Gene Symbol:REM2 ( FLJ38964 )
Gene Full Name: RAS (RAD and GEM)-like GTP binding 2
Band: 14q11.2
Quick LinksEntrez ID:161253; OMIM: NA; Uniprot ID:REM2_HUMAN; ENSEMBL ID: ENSG00000139890; HGNC ID: 20248
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of REM2 mRNAaffects expression 16483693
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of REM2 mRNAincreases expression 20382639
C055494 caffeic acid phenethyl ester [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of REM2 mRNAaffects cotreatment|decreases expression 20360939
D002995 Clofibric Acid Clofibric Acid affects the expression of REM2 mRNAaffects expression 17602206
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of REM2 mRNAaffects cotreatment|decreases expression 20360939
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.1018287403
MESH:D000236 Adenoma Diethylnitrosamine 3.0310737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 4.4417620307 19052882 18056438 19061943 17162532 16434500
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.1917474063
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 1.8718788625 19822196 17138121 16288022 20514400 3084413 16328049 18971187 19701751 16807293 16540662 21159647 16569478 18665156 16698587 11831363 19171122 16779866 18494052 17761372 19383236 18393292 19107877 20084675 20727157 20935162 17162532 18785209 10672840 19418558 20214788 20512989 17055752 18210153 19208518 10737359 16878318 19519916 16502159 17428255 18506893 20007298 19539802 19394651 18978308 3581430 20101231 20432363 16830150 18056438 17978847 20524982 16935385 19052882 19919837 18691550 16681979 19335982 17173139
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.4720889678
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 7.472727394 7505956 17174075 21159647
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 4.0119052882
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 2.2520387270
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 2.1319107877
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.7316302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1420426865
MESH:D005234 Fatty Liver Diethylnitrosamine 3.5620387270 21071580
MESH:D007249 Inflammation Diethylnitrosamine 2.5318785209
MESH:D007414 Intestinal Neoplasms caffeic acid phenethyl ester 4.9310783313
MESH:D007674 Kidney Diseases caffeic acid phenethyl ester 3.7315369732
MESH:D015473 Leukemia, Promyelocytic, Acute caffeic acid phenethyl ester 4.2116766008
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.9918407596 19638242 20032147 18665156 18522880
MESH:D008107 Liver Diseases Diethylnitrosamine 2.1617034775
MESH:D008113 Liver Neoplasms Clofibric Acid 5.1317602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 5.1312112319 2422723 19996281 18754104 15175105 20137499 21167192 2862719 19294768 19090486 18648771 12771043 19499222 9163691 19690152 19073162 19254457 20434301 21278145 21047994 19426721 18644402 20101389 20501860 19255062 20452335 18977376 20118626 20583210 18978307 19638242 19551842 15885732 19833225 21071580 19812893 19850985 16942905 10737359 20405173 19256749 19427195 20492335 19642983
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 2.8321159647 3124819 18282651 18093689 16842330 2563599 18308698 17174075 19009564 18775883 19539802 17942915 16267830 19519916 18544905 9362446 17854601 19126423 19004024 18164116 18079962 18253720
MESH:D008175 Lung Neoplasms Diethylnitrosamine 1.766695378 20970405 21163286 20512841
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.683581430 9029167
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.6520387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.7320387270
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.5216540662
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.882563599
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 1.7618456281
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 3.257505956
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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