AutismKB 2.0

Annotation Detail for ZFPM1


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Basic Information Top
Gene Symbol:ZFPM1 ( FOG,FOG1,ZNF408,ZNF89A )
Gene Full Name: zinc finger protein, multitype 1
Band: 16q24.2
Quick LinksEntrez ID:161882; OMIM: 601950; Uniprot ID:FOG1_HUMAN; ENSEMBL ID: ENSG00000179588; HGNC ID: 19762
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
200070Signaling events mediated by HDAC Class I
200130C-MYB transcription factor network
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of ZFPM1 mRNAdecreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of ZFPM1 mRNAaffects expression 17562736
D004317 Doxorubicin Doxorubicin results in decreased expression of ZFPM1 mRNAdecreases expression 16243910
D004958 Estradiol Estradiol affects the expression of ZFPM1 mRNAaffects expression 15598610
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of ZFPM1 mRNAaffects expression 17555576
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of ZFPM1 mRNAincreases expression 12057914
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of ZFPM1 mRNAaffects binding|decreases expression|increases activity 19710929
D018038 Sodium Selenite Sodium Selenite results in increased expression of ZFPM1 mRNAincreases expression 18175754
D013629 Tamoxifen Tamoxifen affects the expression of ZFPM1 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin binds to AHR protein] which results in decreased expression of ZFPM1 mRNAaffects binding|decreases expression 16214954
D014212 Tretinoin Tretinoin results in increased expression of ZFPM1 mRNAincreases expression 16604517
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.7614745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.0415322242 11752688 14514962
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.1617505938
MESH:D055371 Acute Lung Injury Lipopolysaccharides 9.5511850527 18653653
MESH:D055371 Acute Lung Injury pirinixic acid 9.5518653653
MESH:D000230 Adenocarcinoma Doxorubicin 7.2717418594
MESH:D000230 Adenocarcinoma Estradiol 7.2711473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 7.2714692618
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.833712494
MESH:D018248 Adenoma, Liver Cell pirinixic acid 10.5616434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 10.5616835633
MESH:D000419 Albuminuria Doxorubicin 4.7021441931
MESH:D000505 Alopecia Tretinoin 3.7315955085
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.0811748828
MESH:D000799 Angioedema Acetaminophen 4.0610982225
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.6411256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.4815885639
MESH:D001169 Arthritis, Experimental Tretinoin 7.4816412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2916292516
MESH:D001249 Asthma Tretinoin 2.3816456186
MESH:D001321 Autistic Disorder Acetaminophen 1.4118445737
MESH:D001471 Barrett Esophagus Tretinoin 4.5616935849
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.241440618 11289319
MESH:D001778 Blood Coagulation Disorders pirinixic acid 16.1119483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 16.1112125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 16.1116206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.0115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.8515746008
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.9214601052
MESH:D001932 Brain Neoplasms Doxorubicin 3.9417150277
MESH:D001943 Breast Neoplasms Doxorubicin 2.3716264153 15567936 16096432 16322301 17983394 16935488 16115903 15939500 15993339 15994142 16826403 17426702 11325840 15634643 17369602 15136595 18628466 15692762 18695136 18382427 18234424 16595493 15668708 19526202
MESH:D001943 Breast Neoplasms Estradiol 2.3716675129 12948864 17289903 18497071 19861407 17018787 17261762 14630087
MESH:D001943 Breast Neoplasms Tamoxifen 2.3718984771 16873071 16202921 19487384 20005174 17049068 18855134 19189210 19142967 16818667 18351453 19244106 18629630 18997820 11161223 19189212 18425577 17440819 19289846 17893378 20135344 20544844 17242785 19288272 19155303 16273361 18815881 19115204 20065188 17261762 19410462 21152245 19059307 18821012 15668708 21138602 19011961 20859285 19200415 15565566 20390343 19066611 19221464 19103187 19084267
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.3720435547
MESH:D001943 Breast Neoplasms Tretinoin 2.3716873071 16443354 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.7816813970
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.6616111702
MESH:D002276 Carcinoid Tumor Doxorubicin 5.0316051944
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.9116835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.6819066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.3816168501
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 11.663581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 11.663084413
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 11.6618059187 16234567 16023760 17876044
MESH:D006528 Carcinoma, Hepatocellular Estradiol 11.6616924424
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 11.6616924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 11.661917145
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 6.757296757
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 6.751485588 16201981
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 4.906189445
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 4.9016096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.7517572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.4418670907 16120746 18850075
MESH:D009202 Cardiomyopathies Doxorubicin 3.6215476868 17382496 17308081 16278810 17519947 15811867 16455267 17007740 16242529 16952015 17131338 16269455 17329180 17928571 17924179 16651473 16109756 15505089 16364871 18627295 16731534 17974986 15792986 16612575 17351982
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.9816243910 17334414
MESH:D002386 Cataract Acetaminophen 7.4810977129
MESH:D002386 Cataract Tretinoin 7.4817460283
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 6.977505956
MESH:D002471 Cell Transformation, Neoplastic Estradiol 6.9718566989
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.7816129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.2916835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 13.989022650 19486331
MESH:D002779 Cholestasis Ethinyl Estradiol 13.9816105132 15861022 17333356 17110522 17681005 16919318 11677210
MESH:D002779 Cholestasis pirinixic acid 13.9819176532
MESH:D002822 Choriocarcinoma Tretinoin 5.3816461808
MESH:D019457 Chromosome Breakage Sodium Selenite 4.9315894690
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.9415668235 12621046 8697196 15340226 16354765
MESH:D002972 Cleft Palate Tretinoin 5.949407595
MESH:D003092 Colitis Tretinoin 3.8817035595
MESH:D015179 Colorectal Neoplasms Doxorubicin 2.1418802399 18259882
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.1817141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4810048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Tretinoin 2.489211117 16925845 9224671 14991402 9142499 9125849 10589399 17551590 9664655 8800419
MESH:D003711 Demyelinating Diseases Tamoxifen 4.5419031437
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.978156756 2524372 12868966 18759878 11906362 14531868 11298694 8970840
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4818249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.643621924 2952479
MESH:D003920 Diabetes Mellitus Sodium Selenite 3.9016285004
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6917107852
MESH:D003928 Diabetic Nephropathies Estradiol 9.2619279558
MESH:D003928 Diabetic Nephropathies Tamoxifen 9.2619279558
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 12.439653073 18289764 11289319 9328219 6482804 6679447 9022650 7440962 18648102 16192314 18692083 1440618 8291058
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 12.4317522070 18713872 15968718 17562736 19085960 11529661 12392966 14986274 15619225 19416960 16109766 11739529 11421492 12594235 16177239 14725611 16081117 11743745 12958197 19370779 10774834 12153990 16227642 14550746 11834606 12540782 11287661 19164858 18071297 10663392 11461765 17906064 16485898 19923254 2444490 16781746 19739265 12705907 10915739 16393943 19420014
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 12.4317416283
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 12.4315131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 12.4320420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.3219426721
MESH:D004362 Drug Toxicity Doxorubicin 8.4618602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 8.4611462148
MESH:D004487 Edema pirinixic acid 7.0012083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 7.0011000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 12.6818230668 15322242 16714409
MESH:D004489 Edema, Cardiac Tretinoin 12.6818230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 9.4912538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 9.4919031437
MESH:D016889 Endometrial Neoplasms Doxorubicin 18.5217359293
MESH:D016889 Endometrial Neoplasms Estradiol 18.5211473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Tamoxifen 18.5219155303 16202921 20544844 17893378
MESH:D016889 Endometrial Neoplasms Tretinoin 18.5216569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.159294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 5.3718037988
MESH:D019446 Endotoxemia Lipopolysaccharides 4.5917637181 15328337 15821434
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.143581430
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 9.1811564622
MESH:D005124 Eye Abnormalities Tretinoin 9.1816938888 9664655
MESH:D005234 Fatty Liver Ethinyl Estradiol 13.8715345470
MESH:D005234 Fatty Liver pirinixic acid 13.8720131406 19236843
MESH:D005234 Fatty Liver Tamoxifen 13.8714986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.3116709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.6311858732
MESH:D005334 Fever Lipopolysaccharides 4.1411852909 9205823
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.246705139
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.7214745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 12.1019069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 12.1019069698
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 9.2120067830
MESH:D005355 Fibrosis Tretinoin 9.2117994277
MESH:D005756 Gastritis Acetaminophen 3.8916983495
MESH:D005909 Glioblastoma Doxorubicin 7.5417150277
MESH:D005909 Glioblastoma Tretinoin 7.5417312396
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.197505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.8110696789
MESH:D006258 Head and Neck Neoplasms Doxorubicin 8.1515692506
MESH:D006258 Head and Neck Neoplasms Tretinoin 8.1516096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.3816084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.7610048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 6.7614991402 9664655
MESH:D006331 Heart Diseases Doxorubicin 3.5812587719 16244371 16330681 18674790 16879835 16144979 16495754 17888722 17875725 18006777 16707910 16244372 14766674
MESH:D006333 Heart Failure Doxorubicin 7.3217481944
MESH:D006333 Heart Failure pirinixic acid 7.3220558911
MESH:D006394 Hemangiosarcoma Doxorubicin 4.0415692506
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 4.5216366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.4811000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.676705139
MESH:D006529 Hepatomegaly pirinixic acid 8.8518467677 19772884 16221962 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 8.8516120746 15340226 12621046
MESH:D006558 Herpes Genitalis Estradiol 5.2515709030
MESH:D006689 Hodgkin Disease Doxorubicin 3.5315147373 17606976 18501091
MESH:D019584 Hot Flashes Estradiol 3.9717088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.268697196 15340226 18606429 16959395 16354765
MESH:D006930 Hyperalgesia Acetaminophen 8.0016870215
MESH:D006930 Hyperalgesia Tretinoin 8.0016870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.7416778211
MESH:D006943 Hyperglycemia pirinixic acid 3.3120558911
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.1115034207
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9518670907 18850075
MESH:D007021 Hypospadias Ethinyl Estradiol 3.9816569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.6112013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.5717937319
MESH:D007249 Inflammation Lipopolysaccharides 8.7417255318 17237260 17963957 9205823 12878042
MESH:D007249 Inflammation Tamoxifen 8.7419457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 8.7412878042 12200463
MESH:D007333 Insulin Resistance Estradiol 12.8316627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 12.8316306350
MESH:D007333 Insulin Resistance Sodium Selenite 12.8314714311
MESH:D007410 Intestinal Diseases Tretinoin 3.9417994277
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.7817255318
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.249022650 8074119
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 10.4016580747
MESH:D007569 Jaw Abnormalities Tretinoin 10.4017551590 15992940
MESH:D007674 Kidney Diseases Acetaminophen 10.5215629191 12587719
MESH:D007674 Kidney Diseases Doxorubicin 10.5216775033 15699352 15369732
MESH:D007674 Kidney Diseases Estradiol 10.5215618244
MESH:D007676 Kidney Failure, Chronic Doxorubicin 4.2916707910
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 13.106582329
MESH:D007680 Kidney Neoplasms Estradiol 13.1015610895
MESH:D007680 Kidney Neoplasms Tamoxifen 13.1018625569
MESH:D007938 Leukemia Tretinoin 2.8317143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 5.3716085563
MESH:D007951 Leukemia, Myeloid Tretinoin 3.8416932348 16482212 19285840
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.1017596541 19850784 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.2417712046 16331271 19642359 16823087 19035177 16935935 16140955 16788101 17107899 16766008 17339181 17301526 9834237 19029980 17506722 12679006 19075265 17294898 17361223 19225113 17368321 17649720 17217047 16891316 15748426
MESH:D007970 Leukopenia Lipopolysaccharides 4.8915821434
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.419224671
MESH:D008064 Lipidoses Tamoxifen 3.2515342952 17567588
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.289327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 11.1916595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 11.1914659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 11.1912878042
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 11.1915474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 11.1918564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 11.1912878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 11.1916248980 18397230
MESH:D008107 Liver Diseases Acetaminophen 1.6612587719 19784758 16610002 19460945 19014921 16611625 11587558 12969438
MESH:D017114 Liver Failure, Acute Acetaminophen 3.3717185352 16871587
MESH:D008113 Liver Neoplasms pirinixic acid 7.6120007298 15890375 16377806
MESH:D008113 Liver Neoplasms Tamoxifen 7.6116684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 7.6116984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 10.336587162 1399818 598648 3712494
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 10.3317085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 10.3312151625
MESH:D055370 Lung Injury Lipopolysaccharides 4.1821114838
MESH:D008175 Lung Neoplasms Doxorubicin 3.506189445 17418594
MESH:D008175 Lung Neoplasms Tamoxifen 3.5018625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.5019555203 11884234
MESH:D008223 Lymphoma Doxorubicin 3.5616098063
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 4.2114737004
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.9117654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.7415621674
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.9519428831
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 10.5115458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 10.5111408345 16891317 17203775 11807958
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 10.5111731420 19196722 14580682 16827153 19196723
MESH:D020149 Manganese Poisoning Estradiol 13.3919453300
MESH:D020149 Manganese Poisoning Tamoxifen 13.3919453300
MESH:D008527 Medulloblastoma Tretinoin 2.8317453147
MESH:D008545 Melanoma Doxorubicin 5.2616827129
MESH:D008545 Melanoma Tamoxifen 5.2612393984 19393235
MESH:D008545 Melanoma Tretinoin 5.2616752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.3815990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.7419513568
MESH:D008591 Meningomyelocele Tretinoin 4.6016940565
MESH:D008654 Mesothelioma Doxorubicin 3.1117638057
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.6415792986
MESH:D052016 Mucositis Doxorubicin 4.9817415656
MESH:D009135 Muscular Diseases pirinixic acid 3.6816239165
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.1517596541
MESH:D009203 Myocardial Infarction Doxorubicin 5.8819429709 15857846
MESH:D009203 Myocardial Infarction pirinixic acid 5.8819151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.1312213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 8.6116810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 8.6116411023
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 9.813581430
MESH:D009362 Neoplasm Metastasis Doxorubicin 9.8118259882
MESH:D009362 Neoplasm Metastasis Tamoxifen 9.8119393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5519410462
MESH:D009369 Neoplasms pirinixic acid 5.1217405874
MESH:D009369 Neoplasms Tretinoin 5.1216594593 16946489
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.2219189210 19196722 19200415
MESH:D009389 Neovascularization, Pathologic Estradiol 3.9317289903
MESH:D009401 Nephrosis Doxorubicin 4.9416636307 16899518
MESH:D009404 Nephrotic Syndrome Doxorubicin 4.1215640375 16889571
MESH:D009421 Nervous System Malformations Estradiol 17.3116427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 17.3114600291
MESH:D009421 Nervous System Malformations Tretinoin 17.319125849
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 7.526679447
MESH:D009436 Neural Tube Defects Tretinoin 7.529142499
MESH:D009447 Neuroblastoma Doxorubicin 3.3315555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.9918514411
MESH:D009765 Obesity pirinixic acid 1.8420558911
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.554026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.243988306
MESH:D012516 Osteosarcoma Doxorubicin 4.2315930896
MESH:D010051 Ovarian Neoplasms Estradiol 4.9319401270
MESH:D010051 Ovarian Neoplasms Tretinoin 4.9316936753
MESH:D010146 Pain Acetaminophen 6.9816870215
MESH:D010146 Pain Tretinoin 6.9816870215
MESH:D010190 Pancreatic Neoplasms Tretinoin 2.5015976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.8411578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.667296757
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.4712520081
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.696228378
MESH:D003557 Phyllodes Tumor Doxorubicin 5.3717983394
MESH:D010997 Pleural Neoplasms Doxorubicin 5.3717638057
MESH:D011014 Pneumonia Lipopolysaccharides 4.7512224865 11605937
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.7218163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.3811118676 11222880 11896295 11399792
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 4.0220887781
MESH:D011471 Prostatic Neoplasms Doxorubicin 2.0715749863 15897917 16729912 16868541 18437689 16888761
MESH:D011471 Prostatic Neoplasms Estradiol 2.0716740699
MESH:D011471 Prostatic Neoplasms Sodium Selenite 2.0718760546
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.0715067354
MESH:D011507 Proteinuria Tretinoin 3.7516636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.5116919318 15861022
MESH:D011625 Pterygium Tretinoin 4.9916723453
MESH:D051437 Renal Insufficiency Doxorubicin 4.4017922066
MESH:D015427 Reperfusion Injury pirinixic acid 2.4519058328
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.8210835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.0018990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.483692021
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.2516283617 16116481
MESH:D012509 Sarcoma Doxorubicin 4.1217203757 15625365 16767912 18313854 15675481 17710206
MESH:D012512 Sarcoma, Ewing's Doxorubicin 4.4016326096 14601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.9817846226
MESH:D012878 Skin Neoplasms Doxorubicin 9.8215692506
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.8216192470
MESH:D012878 Skin Neoplasms Tretinoin 9.8216467112
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.7416767912 17203757 15625365
MESH:D013088 Spermatocele Ethinyl Estradiol 12.3016709447
MESH:D013088 Spermatocele Tamoxifen 12.3016709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.2319457130
MESH:D013274 Stomach Neoplasms Tretinoin 1.8017261132
MESH:D013921 Thrombocytopenia Lipopolysaccharides 4.3015821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.7711994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.2815669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.1212697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 12.643712494 1399818 7505956 6582329 6587162
MESH:D013964 Thyroid Neoplasms Doxorubicin 12.6416010429 17909728
MESH:D013964 Thyroid Neoplasms Tretinoin 12.6417045167 16026305
MESH:D013978 Tibial Fractures Estradiol 4.9019048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.9216051514
MESH:D014376 Tuberculosis Tretinoin 3.3116040207
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 8.648074119
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 8.6417653716
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 8.6417572228 8653321 16712894
MESH:D014581 Urticaria Acetaminophen 3.1210982225
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.8116129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.4614692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.8316752155
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.8112125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.6814671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 4.4017678736 17638931 17334414 16364871
MESH:D014820 Vitiligo Tretinoin 4.2216761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.4715886252
MESH:D009396 Wilms Tumor Tretinoin 4.0916287080
Pathway ID Pathway Name
REACT:604 Hemostasis
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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