AutismKB 2.0

Annotation Detail for DCN


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Basic Information Top
Gene Symbol:DCN ( CSCD,DSPG2,PG40,PGII,PGS2,SLRR1B )
Gene Full Name: decorin
Band: 12q21.33
Quick LinksEntrez ID:1634; OMIM: 125255; Uniprot ID:PGS2_HUMAN; ENSEMBL ID: ENSG00000011465; HGNC ID: 2705
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04350TGF-beta signaling pathway
No data
Pathway IDPathway Name
200044Validated transcriptional targets of AP1 family members Fra1 and Fra2
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1724Vascular disease
1990Skin disease, Genetic
1739Oral cancer
1848Embryoma
1891Ptosis
1904Diabetes mellitus
2044Pre-Eclampsia
2129Thyroid cancer
2214Malignant glioma
2251Osteosarcoma
Desease Name
renal disease
diabetes, type 1
IMMUNE
No data
Desease Name
Corneal dystrophy, congenital stromal
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of DCN mRNAaffects expression 21346803
C019499 2-nitrofluorene 2-nitrofluorene results in increased expression of DCN mRNAincreases expression 14600272
C016583 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of DCN mRNAincreases expression 14600272
D000082 Acetaminophen Acetaminophen affects the expression of DCN mRNAaffects expression 17562736
C109238 acyline acyline results in decreased expression of DCN mRNAdecreases expression 17510436
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of DCN proteinaffects expression 20106945
D016604 Aflatoxin B1 Aflatoxin B1 results in increased expression of DCN mRNAincreases expression 14600272
D000643 Ammonium Chloride Ammonium Chloride affects the expression of DCN mRNAaffects expression 16483693
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of DCN mRNAincreases expression 20106945
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of DCN mRNAincreases expression 19150397
C002791 bismuth tripotassium dicitrate bismuth tripotassium dicitrate results in increased expression of DCN mRNAincreases expression 15912405
C006780 bisphenol A bisphenol A results in decreased expression of DCN mRNAdecreases expression 20739668
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of DCN mRNAaffects expression 15963342
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of DCN mRNAincreases expression 16239168
D003035 Cobalt [tungsten carbide binds to Cobalt] which results in decreased expression of DCN mRNAaffects binding|decreases expression 20105288
C018021 cobaltous chloride cobaltous chloride results in decreased expression of DCN mRNAdecreases expression 20105288
D003513 Cycloheximide Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of DCN mRNA]decreases expression|decreases reaction 11007951
D003520 Cyclophosphamide DCN protein inhibits the reaction [TGFB1 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Cisplatin co-treated with Melphalan co-treated with Thiotepa]]affects cotreatment|decreases reaction|decreases response to substance 9509296
D003907 Dexamethasone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of DCN mRNAaffects cotreatment|decreases expression 16054899
D002945 Cisplatin DCN protein inhibits the reaction [TGFB1 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Cisplatin co-treated with Melphalan co-treated with Thiotepa]]affects cotreatment|decreases reaction|decreases response to substance 9509296
D019259 Lamivudine [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of DCN mRNAaffects cotreatment|increases expression 16931933
D019259 Lamivudine [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of DCN mRNAaffects cotreatment|increases expression 16931933
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of DCN mRNAincreases expression 19638242
D004054 Diethylstilbestrol Diethylstilbestrol results in decreased expression of DCN mRNAdecreases expression 16804899
D002117 Calcitriol Calcitriol results in decreased expression of DCN mRNAdecreases expression 16002434
D004128 Dimethylnitrosamine Dimethylnitrosamine results in increased expression of DCN mRNAincreases expression 14600272
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of DCN mRNAdecreases expression 19400957
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of DCN mRNAdecreases expression 19400957
17557909
D019469 Indinavir [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of DCN mRNAaffects cotreatment|increases expression 16931933
D015056 1-Methyl-3-isobutylxanthine [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of DCN mRNAaffects cotreatment|decreases expression 16054899
D001556 Lindane Lindane results in decreased expression of DCN mRNAdecreases expression 17785943
D008558 Melphalan DCN protein inhibits the reaction [TGFB1 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Cisplatin co-treated with Melphalan co-treated with Thiotepa]]affects cotreatment|decreases reaction|decreases response to substance 9509296
D008769 Methylnitronitrosoguanidine Methylnitronitrosoguanidine results in decreased expression of DCN mRNAdecreases expression 15120970
C000873 methylprednisolone acetate methylprednisolone acetate results in decreased expression of DCN mRNAdecreases expression 15693093
D015735 Mifepristone Mifepristone results in increased expression of DCN mRNAincreases expression 17584828
D010126 Ozone Ozone results in decreased expression of DCN mRNAdecreases expression 12763052
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of DCN mRNA]affects reaction|decreases expression 19482888
D010634 Phenobarbital Phenobarbital results in decreased expression of DCN mRNAdecreases expression 19482888
C009166 retinol acetate retinol acetate results in increased expression of DCN mRNAincreases expression 16772331
C089730 rosiglitazone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of DCN mRNAaffects cotreatment|decreases expression 16054899
C010327 salinomycin salinomycin results in decreased expression of DCN mRNAdecreases expression 19682730
D019258 Saquinavir [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of DCN mRNAaffects cotreatment|increases expression 16931933
D013467 Sulindac Sulindac results in decreased expression of DCN mRNAdecreases expression 11507085
D013629 Tamoxifen Tamoxifen results in decreased expression of DCN mRNAdecreases expression 19400957
D013629 Tamoxifen Tamoxifen results in decreased expression of DCN mRNAdecreases expression 19400957
D013749 Tetrachlorodibenzodioxin Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of DCN mRNA]decreases expression|decreases reaction 11007951
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of DCN mRNAdecreases expression 11007951
D013749 Tetrachlorodibenzodioxin AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of DCN mRNA]decreases reaction|increases expression 14728982
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of DCN mRNAincreases expression 14728982
16922920
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of DCN mRNAincreases expression 15644576
D013852 Thiotepa DCN protein inhibits the reaction [TGFB1 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Cisplatin co-treated with Melphalan co-treated with Thiotepa]]affects cotreatment|decreases reaction|decreases response to substance 9509296
C002802 tungsten carbide [tungsten carbide binds to Cobalt] which results in decreased expression of DCN mRNAaffects binding|decreases expression 20105288
C025643 vinclozolin vinclozolin affects the expression of DCN mRNAaffects expression 19015723
D014810 Vitamin E Vitamin E results in increased expression of DCN mRNAincreases expression 19244175
D015215 Zidovudine [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of DCN mRNAaffects cotreatment|increases expression 16931933
D015215 Zidovudine [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of DCN mRNAaffects cotreatment|increases expression 16931933
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Sulindac 11.4014745880
MESH:D000008 Abdominal Neoplasms Tamoxifen 11.4014745880
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 6.726195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 6.7215322242 14514962 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.0818287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.4617505938
MESH:D000163 Acquired Immunodeficiency Syndrome Zidovudine 4.369612607
MESH:D058186 Acute Kidney Injury Cisplatin 7.6517670903 12690470 15814532
MESH:D058186 Acute Kidney Injury Sulindac 7.657897758
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 12.0220127859 20464547
MESH:D000230 Adenocarcinoma Cisplatin 12.0211798837 17638652
MESH:D000230 Adenocarcinoma Dimethylnitrosamine 12.0216033868
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 12.0214692618
MESH:D000230 Adenocarcinoma Sulindac 12.0211910360
MESH:D000236 Adenoma 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 17.9816176798
MESH:D000236 Adenoma Benzo(a)pyrene 17.986695378
MESH:D000236 Adenoma Diethylnitrosamine 17.986695378 10737359
MESH:D000236 Adenoma Dimethylnitrosamine 17.9819555203
MESH:D000236 Adenoma Sulindac 17.9810223192
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 14.5916434500 17162532 19061943 18056438 17620307 19052882
MESH:D018248 Adenoma, Liver Cell Phenobarbital 14.5917620307
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 14.5916835633
MESH:D011125 Adenomatous Polyposis Coli Sulindac 4.1911874996 15623613 11535846 12394442 19003578 17611924 16460482
MESH:D000382 Agricultural Workers' Diseases Lindane 3.9012661182
MESH:D000544 Alzheimer Disease Ozone 4.0515513908
MESH:D000544 Alzheimer Disease rosiglitazone 4.0519621015
MESH:D000686 Amyloidosis Diethylstilbestrol 4.0315469931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.5411748828
MESH:D000799 Angioedema Acetaminophen 3.3610982225
MESH:D001008 Anxiety Disorders vinclozolin 3.2619015723
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.6119183758
MESH:D001161 Arteriosclerosis Cyclophosphamide 8.6315014928
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 8.6311256880
MESH:D001169 Arthritis, Experimental Dexamethasone 6.3617659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.3615885639
MESH:D001172 Arthritis, Rheumatoid Ozone 2.4315570426
MESH:D001249 Asthma Ozone 2.4816373670 17854713
MESH:D001321 Autistic Disorder Acetaminophen 1.4818445737
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 2.6212125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.3115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.4515746008
MESH:D019046 Bone Marrow Neoplasms Cisplatin 4.4014601052
MESH:D001862 Bone Resorption bisphenol A 3.4411985600
MESH:D001913 Bowen's Disease Sulindac 4.8711207687
MESH:D001943 Breast Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 11.7120146248
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 11.7120146248 17474063
MESH:D001943 Breast Neoplasms bisphenol A 11.7117123778
MESH:D001943 Breast Neoplasms Calcitriol 11.7111237771
MESH:D001943 Breast Neoplasms Cisplatin 11.7119526202 18382427
MESH:D001943 Breast Neoplasms Cobalt 11.7115986119
MESH:D001943 Breast Neoplasms Cyclophosphamide 11.7118234424 16978400 17388661 15136595 17020986 15093573 11325840 12006526 18323546
MESH:D001943 Breast Neoplasms Diethylnitrosamine 11.7117474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 11.7115324884 17129689
MESH:D001943 Breast Neoplasms Lindane 11.7114688026
MESH:D001943 Breast Neoplasms salinomycin 11.7119682730
MESH:D001943 Breast Neoplasms Sulindac 11.7116642371
MESH:D001943 Breast Neoplasms Tamoxifen 11.7119189212 16202921 19189210 19289846 19221464 21138602 18815881 18855134 19200415 16273361 17893378 19410462 21152245 18821012 19115204 18997820 19288272 19244106 20390343 17440819 17261762 18351453 18629630 20859285 19155303 19066611 15668708 16873071 15565566 16818667 20544844 18425577 19011961 19059307 11161223 19487384 19142967 17049068 20135344 18984771 19084267 20005174 17242785 20065188 19103187
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 11.7120435547
MESH:D016535 Bronchial Hyperreactivity Ozone 3.3015516495 14754758 18417511 19059883 18315731 16777450 17626835
MESH:D002100 Cachexia Ozone 4.2616183385
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 8.3910355542 16050911 3786805 16011737 15673190 16097048 15700767 16124888 15721981 16192424 16227642 18705752
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 8.3916050911
MESH:D002277 Carcinoma Dimethylnitrosamine 7.1019555203
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.1016835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.0419066611
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 20.8416705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 20.843084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 20.8421507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 20.8418788625
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 20.8417982673
MESH:D006528 Carcinoma, Hepatocellular Cyclophosphamide 20.8419701751
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 20.8419107877 18506893 20727157 17055752 19383236 3084413 18494052 19394651 16328049 10672840 20101231 3581430 16540662 19052882 16830150 17761372 19208518 16288022 16698587 16935385 16502159 17428255 18978308 19919837 17162532 20935162 16569478 19171122 18665156 17173139 20524982 20514400 20512989 17138121 19822196 20214788 19418558 16878318 21159647 18210153 16807293 19701751 19519916 17978847 11831363 19539802 16779866 18788625 20432363 18393292 16681979 20084675 18691550 19335982 18971187 18056438 18785209 20007298 10737359
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 20.8415948411 16924424
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 20.846705139 1701930 17173139 20007298 20935162
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 20.8416924424
MESH:D002278 Carcinoma in Situ bisphenol A 4.5117123778
MESH:D018827 Carcinoma, Lewis Lung Cyclophosphamide 4.4116152834
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 2.8612023789 16685392
MESH:D002292 Carcinoma, Renal Cell Cyclophosphamide 3.3016201981
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 9.5020419170
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 9.5011237771
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 9.506189445 18337622 17066447
MESH:D002294 Carcinoma, Squamous Cell Dimethylnitrosamine 9.5016033868
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.2017572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.0916120746 18670907 18850075
MESH:D002386 Cataract Acetaminophen 2.2910977129
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 9.4120889678
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 9.417505956 2727394 17174075 21159647
MESH:D002471 Cell Transformation, Neoplastic Methylnitronitrosoguanidine 9.412727394
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.794080065
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 7.9919052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 7.9916835633
MESH:D002779 Cholestasis Ethinyl Estradiol 2.5216105132 15861022 17681005 17333356 16919318 17110522 11677210
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 1.8915668235 8697196 16354765 15340226 12621046
MESH:D003110 Colonic Neoplasms Dexamethasone 3.8215824018
MESH:D003110 Colonic Neoplasms Sulindac 3.8212902858 12458338
MESH:D015179 Colorectal Neoplasms Cisplatin 2.8415273666
MESH:D015179 Colorectal Neoplasms Sulindac 2.8410666051 11197048 18059344 11076880
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.6617141729 14669216
OMIM:610048 CORNEAL DYSTROPHY, CONGENITAL STROMAL marker/mechanism
MESH:D019465 Craniofacial Abnormalities Dexamethasone 3.4617728286
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.4610048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Vitamin E 3.4619769572
MESH:D003456 Cryptorchidism Diethylstilbestrol 9.8716002989 12952375
MESH:D003456 Cryptorchidism vinclozolin 9.8714966744
MESH:D003490 Cyanosis 2,4-dinitrotoluene 3.5518551238
MESH:D003556 Cystitis Cyclophosphamide 4.5018093676 16413132 18433785 12388444 17979934 10498854 11948286 16614059 16651033 18372110 18710439 15276878 12913760 15643279 17010015 18295254 10700343 12161096 18483878 16989017
MESH:D003711 Demyelinating Diseases Tamoxifen 3.9019031437
MESH:D017449 Dermatitis, Allergic Contact cobaltous chloride 5.9911298694 15059100 16823706
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 5.9912438553
MESH:D003920 Diabetes Mellitus rosiglitazone 3.9017446233
MESH:D003921 Diabetes Mellitus, Experimental Cyclophosphamide 3.6810990075 15331540 11751995
MESH:D003922 Diabetes Mellitus, Type 1 Cyclophosphamide 3.0618772604
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 6.3420387270
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 6.3412642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.3417107852
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.0819279558
MESH:D003930 Diabetic Retinopathy Sulindac 4.7217621415 12861449
MESH:D003967 Diarrhea Dexamethasone 3.267237001
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 13.0921346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 13.0915968718 11461765 19370779 18071297 11739529 19416960 12153990 11834606 19164858 16227642 18713872 14986274 11743745 16081117 16485898 19739265 10774834 16109766 16177239 14725611 2444490 16781746 15619225 12958197 19420014 17522070 12392966 11421492 17562736 11529661 16393943 10663392 12594235 11287661 12540782 17906064 19085960 14550746 19923254 12705907 10915739
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 13.097179309 19085960 3786805 3732212 15027814 16227642 15998439 7120509 11566570 6623471 10092053 16177239 6884620 4309450 19336974 10915739 7440962 21278145 2869522 17522070 9327722 15968718
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 13.0919107877
MESH:D056486 Drug-Induced Liver Injury Dimethylnitrosamine 13.098172417
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 13.0920420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.6119426721
MESH:D004362 Drug Toxicity Cisplatin 16.7512649298 15033597 12231392 19839026
MESH:D004362 Drug Toxicity Lamivudine 16.7515040536
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 16.7511462148
MESH:D004362 Drug Toxicity Zidovudine 16.7515040536
MESH:D004421 Dystonia Phenobarbital 3.561851702
MESH:C538011 Eales disease Vitamin E 4.229068938
MESH:D004485 Eczema Dexamethasone 4.0112438553
MESH:D004487 Edema Dexamethasone 9.1619703484
MESH:D004487 Edema rosiglitazone 9.1612083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 9.1612711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.4216714409 15322242 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 12.7315138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 12.7312538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 12.7319031437
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 4.2216402032
MESH:D016889 Endometrial Neoplasms marker/mechanism 16804899
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 6.5016804899 15700306
MESH:D016889 Endometrial Neoplasms Tamoxifen 6.5016202921 19155303 17893378 20544844
MESH:D004715 Endometriosis Mifepristone 13.0416134523
MESH:D004715 Endometriosis Sulindac 13.0415652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 13.049294722 10568697
MESH:D004802 Eosinophilia Cyclophosphamide 3.7611006010
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.643659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.393922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.6320417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.146401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.797750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.543659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.6316302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 12.2820426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 12.2816530937
MESH:D004938 Esophageal Neoplasms Cisplatin 12.2816481741 15173087 17638652 15464296 16785472
MESH:D004938 Esophageal Neoplasms Dimethylnitrosamine 12.2817016578
MESH:D004938 Esophageal Neoplasms Sulindac 12.2812235107
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.6511564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 25.2212795759 12631006 15959796 16045604 17595544 61145 16239168 19224547
MESH:D005234 Fatty Liver Diethylnitrosamine 25.2221071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 25.2215345470
MESH:D005234 Fatty Liver rosiglitazone 25.2219196556
MESH:D005234 Fatty Liver Tamoxifen 25.2214986274 19224547
MESH:D005234 Fatty Liver Zidovudine 25.2218299183
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 7.2116534752 16611131 16513791 16002989 15751030
MESH:D052776 Female Urogenital Diseases Tamoxifen 7.2116709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.9911858732
MESH:D018221 Fibromatosis, Abdominal Sulindac 11.3714745880
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 11.3714745880
MESH:D018222 Fibromatosis, Aggressive Sulindac 10.0619069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 10.0619069698
MESH:D005355 Fibrosis Carbon Tetrachloride 7.0618705752
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 7.0620067830
MESH:D005756 Gastritis Acetaminophen 3.1916983495
MESH:D005764 Gastroesophageal Reflux Sulindac 4.5611910360
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.4616973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.8116417039
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 4.4716452187
MESH:D018316 Gliosarcoma Cyclophosphamide 5.0411389073
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.1110696789
MESH:D006086 Graft vs Host Disease Cyclophosphamide 4.5716376943 15172196 11014644
MESH:D006258 Head and Neck Neoplasms Cisplatin 3.3915102660 15464296
MESH:D034381 Hearing Loss Cisplatin 3.9019898482
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 4.0315464296
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 9.5520471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 9.5510048152 11294989
MESH:D006330 Heart Defects, Congenital Vitamin E 9.5516080930
MESH:D006402 Hematologic Diseases Zidovudine 4.2712579204
MESH:D006467 Hemophilia A Cyclophosphamide 4.8211918545
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.9111000095
MESH:D006504 Hepatic Veno-Occlusive Disease Cyclophosphamide 5.0514986274
MESH:D006505 Hepatitis Carbon Tetrachloride 3.1519110552 19900420
MESH:D006509 Hepatitis B Lamivudine 4.6717703166
MESH:D019694 Hepatitis B, Chronic Lamivudine 4.6715274664 15631357 15309715 16476009 12044531
MESH:D006529 Hepatomegaly Phenobarbital 6.9116109766
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 6.9116120746 15340226 12621046
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 5.357520565
MESH:D006548 Hernia, Diaphragmatic Vitamin E 5.3516863852 16490937
MESH:D015658 HIV Infections Indinavir 13.3315388451 11363243 11141242
MESH:D015658 HIV Infections Lamivudine 13.339296927 11141242 17530837 20032539
MESH:D015658 HIV Infections Saquinavir 13.3315388451 11141242
MESH:D015658 HIV Infections Zidovudine 13.3311363243 11698656 17358032 11141242 20032539
MESH:D006689 Hodgkin Disease Cisplatin 6.4616200630 16170182
MESH:D006689 Hodgkin Disease Cyclophosphamide 6.4616135485 17606976
MESH:D019584 Hot Flashes Vitamin E 3.4914716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.5616959395 15340226 8697196 18606429 16354765
MESH:D006930 Hyperalgesia Acetaminophen 6.6416870215
MESH:D006930 Hyperalgesia rosiglitazone 6.6412083418
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.0516899240
MESH:D006965 Hyperplasia Diethylstilbestrol 3.9712960047 14722030
MESH:D006973 Hypertension Cobalt 7.6517039479
MESH:D006973 Hypertension Dexamethasone 7.6517042910
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 7.6518850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.6215338365
MESH:D007021 Hypospadias Diethylstilbestrol 9.7016002989
MESH:D007021 Hypospadias Ethinyl Estradiol 9.7016569931 16945680
MESH:D007077 Ileal Diseases 1-Methyl-3-isobutylxanthine 4.9618306037
MESH:D007154 Immune System Diseases Cyclophosphamide 4.8516076520
MESH:D007246 Infertility Diethylstilbestrol 3.9015036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.0212013081
MESH:D007248 Infertility, Male Cyclophosphamide 9.407193160 16517039
MESH:D007248 Infertility, Male Ethinyl Estradiol 9.4017937319
MESH:D007248 Infertility, Male vinclozolin 9.4016467254
MESH:D007249 Inflammation Dexamethasone 16.538960868 11099482
MESH:D007249 Inflammation Diethylnitrosamine 16.5318785209
MESH:D007249 Inflammation rosiglitazone 16.5312083418
MESH:D007249 Inflammation Sulindac 16.533291741
MESH:D007249 Inflammation Tamoxifen 16.5319457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 16.5312200463 12878042
MESH:D007251 Influenza, Human Vitamin E 3.7316624496
MESH:D007333 Insulin Resistance bisphenol A 6.6816393666
MESH:D007333 Insulin Resistance rosiglitazone 6.6816306350
MESH:D007414 Intestinal Neoplasms Sulindac 4.2212584176 12351151 12628509 10223192 12663524 10213222
MESH:D007417 Intestinal Polyps Sulindac 4.5512394442 11245490
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 2.9116580747
MESH:D007579 Jejunal Diseases 1-Methyl-3-isobutylxanthine 4.9618306037
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.6515464296
MESH:D007674 Kidney Diseases Acetaminophen 8.4612587719 15629191
MESH:D007674 Kidney Diseases Cisplatin 8.4612231392 15190930 19839026 12649298 18289764
MESH:D007674 Kidney Diseases Vitamin E 8.4612488133
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 14.6416705839
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 14.6415003126 16762066 14681315
MESH:D007680 Kidney Neoplasms Tamoxifen 14.6418625569
MESH:D007680 Kidney Neoplasms Zidovudine 14.6412579204
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 4.3111231351
MESH:D007859 Learning Disorders Diethylstilbestrol 3.6017184923
MESH:D007938 Leukemia Cyclophosphamide 3.2410602166
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Cyclophosphamide 3.2817008537 17296974 17802794 18172266 17658394 18587576
MESH:D007945 Leukemia, Lymphoid Thiotepa 5.8110069464
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Zidovudine 3.9920370541
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Cyclophosphamide 8.0810373061
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Thiotepa 8.0810373061
MESH:D007951 Leukemia, Myeloid Thiotepa 5.1110069464
MESH:D007970 Leukopenia Cyclophosphamide 4.4910052129 11830472
MESH:D007984 Leydig Cell Tumor vinclozolin 4.2516417039
MESH:D008064 Lipidoses Tamoxifen 2.8117567588 15342952
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 9.4111408273 17174718 16239168 21278145 16943688 17334410 17157831 11903743 16221502
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 9.4118665156 18522880 20032147 19638242 18407596
MESH:D008103 Liver Cirrhosis Phenobarbital 9.4121047994
MESH:D008105 Liver Cirrhosis, Biliary Sulindac 3.9212468960
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 9.7618418968 10355542 16033810 17721639 17976157 15123356 15876570 15362042 16011737 12741479 16027843 15818738 18420326 12586293 17640975 17761835 12445421 15996030 12609069 18339082 18395095 18279442 18317297 17708605 18705752 18205269 12958196 18210741 18263696 12546737 14716833 17565644 15959796 18472094 18187930 17922224 18429990 14512876 18156304 18472332 18166357 17805973 15057751 15673190 15052691 14716496 17766677 15931870 13678700 15338365 16116963 17823541 16097048 16248980 17525996 18251166 12632512 15893842 16192424 12632514 17900296 17557913 17631135 16136751 12667390 17869086 18481824 18412020 17944888 18277467 16638106 12898905 12649538 14748882 18006644 12445418 18054572 12389079 12666154 15370692 14724832 14620537 15925388 15730626 20821823 16015684 11481614 18376398 17714472 17481882 15650968 18395914 17698563
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 9.7616718785
MESH:D008106 Liver Cirrhosis, Experimental Dimethylnitrosamine 9.7615369754 18364076 18637143 15138612 15383259 15723089 15591649 15479170 14568256 15744066 16169303 15733078 17203207 12925901 18567088 18095165 16627068 15763062 14726149 15366600 17534399 14659978 17201889 17881167 16603200 17196135 15798949 18629640 15161499 15793283 17198567 16570917 14643895 16544323 17348192 17432682 14709902 17666798 18239293 17465448 18672772 17719030 15067225 15492853 17724770 17036385 16042886 15099470 16009107 15504291 15571005 18371158 15864749 15339415 15942678 17640959 15577212 12918455 18210741 15298665 15081153 18237412 15086199 16270385 15842777
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 9.7617347453 15980055
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 9.7618564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 9.7612878042
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 9.7616169303
MESH:D008107 Liver Diseases Acetaminophen 13.9512969438 12587719 19460945 16611625 19014921 16610002 19784758 11587558
MESH:D008107 Liver Diseases Carbon Tetrachloride 13.9516246199 16964402 17285989 15830285 15720792
MESH:D008107 Liver Diseases Diethylnitrosamine 13.9517034775
MESH:D008107 Liver Diseases Lindane 13.951715830
MESH:D008107 Liver Diseases Phenobarbital 13.9519363144
MESH:D008107 Liver Diseases Sulindac 13.9514986274 16867024
MESH:D017093 Liver Failure Carbon Tetrachloride 3.7015123358
MESH:D017114 Liver Failure, Acute Acetaminophen 13.8717185352 16871587
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 13.8716899240 14706259
MESH:D017114 Liver Failure, Acute Dimethylnitrosamine 13.8717457977
MESH:D008113 Liver Neoplasms 2-nitrofluorene 33.9515890375
MESH:D008113 Liver Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 33.9515890375
MESH:D008113 Liver Neoplasms Aflatoxin B1 33.952125692 18177683 9163691 15890375
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 33.9521137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 33.9519294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 33.9520434301 19255062 20492335 15175105 19551842 20101389 2422723 19996281 21071580 18977376 10737359 19254457 2862719 20583210 19073162 21167192 21047994 15885732 20405173 18648771 19090486 20137499 19427195 19499222 20501860 19812893 20118626 19638242 18978307 9163691 19642983 21278145 16942905 12112319 19850985 19426721 19256749 19833225 18644402 18754104 19294768 20452335 12771043 19690152
MESH:D008113 Liver Neoplasms Diethylstilbestrol 33.9515890375 16712894
MESH:D008113 Liver Neoplasms Dimethylnitrosamine 33.9515890375 3113478
MESH:D008113 Liver Neoplasms Phenobarbital 33.958742319 19812893 19482888 15975961 21047994 19073162
MESH:D008113 Liver Neoplasms Tamoxifen 33.9516684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 33.9516984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 19.378603461
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 19.3715583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 19.3716842330 19009564 21159647 18775883 18282651 18544905 18308698 18093689 19519916 17942915 19126423 16267830 17854601 19539802 2563599 18079962 3124819 9362446 19004024 18164116 18253720 17174075
MESH:D008114 Liver Neoplasms, Experimental Dimethylnitrosamine 19.371848544 15603536 6150874
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 19.371399818 18308698 17172636 6150874 2563599
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 19.3712151625
MESH:D008171 Lung Diseases Ozone 6.4319066396 8266340
MESH:D008171 Lung Diseases Vitamin E 6.4316863852
MESH:D008173 Lung Diseases, Obstructive Cobalt 5.406434250
MESH:D055370 Lung Injury Ozone 3.3920417186
MESH:D008175 Lung Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 23.9618508827 16061637 19931552 12438228 15893417 17139156 16401635 15172992 18813816 14755239 9255578
MESH:D008175 Lung Neoplasms Aflatoxin B1 23.9614755239
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 23.9618569708 20464547 18816296 17053015 20064080 20135361 6695378 20869020 18520028
MESH:D008175 Lung Neoplasms Cisplatin 23.966189445 11798837 17225452
MESH:D008175 Lung Neoplasms Dexamethasone 23.9611195469 15824018
MESH:D008175 Lung Neoplasms Diethylnitrosamine 23.9621163286 20512841 6695378 20970405
MESH:D008175 Lung Neoplasms Dimethylnitrosamine 23.9616061637 11884234 19555203
MESH:D008175 Lung Neoplasms Ozone 23.967614698 8597069
MESH:D008175 Lung Neoplasms Sulindac 23.9615713900 19359593
MESH:D008175 Lung Neoplasms Tamoxifen 23.9618625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 23.9611884234 19555203
MESH:D008175 Lung Neoplasms Vitamin E 23.9611062179
MESH:D008175 Lung Neoplasms Zidovudine 23.9618800350
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.6715166399
MESH:D008223 Lymphoma Cyclophosphamide 10.8912854902
MESH:D008223 Lymphoma Diethylstilbestrol 10.8915700306
MESH:D008223 Lymphoma Thiotepa 10.8910069464
MESH:D016393 Lymphoma, B-Cell Cyclophosphamide 4.1616675587
MESH:D008228 Lymphoma, Non-Hodgkin Cyclophosphamide 3.7811911406
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.0316002989
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.2919428831
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 8.3816827153
MESH:D008325 Mammary Neoplasms, Experimental salinomycin 8.3819682730
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 8.3814580682 19196723 11731420 19196722 16827153
MESH:D020149 Manganese Poisoning Tamoxifen 4.0619453300
MESH:D008545 Melanoma Cisplatin 6.5815577323 12374674 16809738 18176117 18505091 12883367 16248763 12393984 16432458 18332650 17761969 11135225 17023156
MESH:D008545 Melanoma Melphalan 6.5814993021 18388930
MESH:D008545 Melanoma Sulindac 6.5816642371
MESH:D008545 Melanoma Tamoxifen 6.5819393235 12393984
MESH:D018328 Melanoma, Amelanotic Cisplatin 9.9215990972
MESH:D018328 Melanoma, Amelanotic Tamoxifen 9.9215990972
MESH:D008546 Melanoma, Experimental Acetaminophen 9.2919513568
MESH:D008546 Melanoma, Experimental Cyclophosphamide 9.2916388313
MESH:D008654 Mesothelioma Cisplatin 3.0417638057
MESH:D024821 Metabolic Syndrome X rosiglitazone 3.9917261469
MESH:D008679 Metaplasia Ozone 4.6210496685
MESH:D048629 Micronuclei, Chromosome-Defective Zidovudine 5.3517358032
MESH:D053842 Microsatellite Instability Methylnitronitrosoguanidine 5.4117671175
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 2.8216381670
MESH:D009101 Multiple Myeloma Dexamethasone 3.1716118317 15867202 15744524
MESH:D020391 Muscular Dystrophy, Facioscapulohumeral marker/mechanism 12868502
MESH:D009164 Mycobacterium Infections Indinavir 4.9321442799
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 3.269809623
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.6412213967
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.0017484760
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.3818551238
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.039029167 3581430
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.0319393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.3519410462
MESH:D009369 Neoplasms Benzo(a)pyrene 16.5211141357
MESH:D009369 Neoplasms Cisplatin 16.5216773208
MESH:D009369 Neoplasms Cyclophosphamide 16.5218854779
MESH:D009369 Neoplasms Diethylstilbestrol 16.5215313581
MESH:D009369 Neoplasms Lindane 16.5216818664 12807735
MESH:D009369 Neoplasms Thiotepa 16.5218854779
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.5219200415 19189210 19196722
MESH:D009395 Nephritis, Interstitial Cisplatin 4.0115464296
MESH:D009421 Nervous System Malformations bisphenol A 13.8111399458 16427766
MESH:D009421 Nervous System Malformations Diethylstilbestrol 13.8111399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 13.8114600291
MESH:D009447 Neuroblastoma Cisplatin 10.238761367
MESH:D009447 Neuroblastoma Cyclophosphamide 10.2316115947 8761367 15176712
MESH:D009447 Neuroblastoma Thiotepa 10.238761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 11.8718514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 11.8720387270
MESH:D019636 Neurodegenerative Diseases Sulindac 11.8717266991 16850258
MESH:D017599 Neuroectodermal Tumors Cisplatin 16.528761367
MESH:D017599 Neuroectodermal Tumors Cyclophosphamide 16.5212837982 8761367
MESH:D017599 Neuroectodermal Tumors Thiotepa 16.528761367 12837982
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.6320387270
MESH:D009503 Neutropenia Cyclophosphamide 3.898291058
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.0212819281 16049721
MESH:D009845 Oligospermia Cyclophosphamide 4.2416517039
MESH:D010018 Osteomalacia Phenobarbital 3.8917016548
MESH:D010049 Ovarian Diseases bisphenol A 4.5111985600
MESH:D010051 Ovarian Neoplasms Cisplatin 4.7719769630 15464296 6897625 17225452
MESH:D010051 Ovarian Neoplasms Mifepristone 4.7716525653
MESH:D010146 Pain Acetaminophen 9.1916870215
MESH:D010146 Pain Cyclophosphamide 9.1912161096 18093676
MESH:D010146 Pain Sulindac 9.193291741
MESH:D010190 Pancreatic Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 18.0012384795
MESH:D010190 Pancreatic Neoplasms Cisplatin 18.0019003803
MESH:D010190 Pancreatic Neoplasms Cyclophosphamide 18.0011332152
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 18.0016540662
MESH:D010190 Pancreatic Neoplasms Phenobarbital 18.0016965848
MESH:D010190 Pancreatic Neoplasms Sulindac 18.0011504793 16820089
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.2511578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.7612520081
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 3.8615464296
MESH:D010538 Peritonitis Ozone 3.6716369182
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.6814722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.2116977796 15687265
MESH:D010997 Pleural Neoplasms Cisplatin 4.8617638057
MESH:D011014 Pneumonia Ozone 3.9218929643 18381685 18007984
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.1118163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 7.762563599
MESH:D011230 Precancerous Conditions Phenobarbital 7.762563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Cyclophosphamide 6.8821297632
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 6.8821297632
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 19.3510548101
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 19.3517184923
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 19.3511118676 11896295 11399792 11222880
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 19.3519015723 18220299 18042343
MESH:D011469 Prostatic Diseases vinclozolin 4.4618220299
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.3015572423
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 3.7820887781
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.7417292933
MESH:D011471 Prostatic Neoplasms bisphenol A 2.7416740699
MESH:D011471 Prostatic Neoplasms Calcitriol 2.7412479363 15754350 16644109 16289102 18247401
MESH:D011471 Prostatic Neoplasms Cyclophosphamide 2.7417136230
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 2.7415846301 15046698 17136230
MESH:D011471 Prostatic Neoplasms Lindane 2.7412661182 14688026
MESH:D011471 Prostatic Neoplasms Melphalan 2.7415749863
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.7415067354
MESH:D011471 Prostatic Neoplasms Vitamin E 2.7415084515
MESH:D011472 Prostatitis vinclozolin 4.4618629315
MESH:D011537 Pruritus Ethinyl Estradiol 2.8416919318 15861022
MESH:D019310 Pseudolymphoma Phenobarbital 4.0112752131
MESH:D011629 Puberty, Precocious bisphenol A 4.3110548101
MESH:D011658 Pulmonary Fibrosis Cobalt 5.726434250
MESH:D011658 Pulmonary Fibrosis Cyclophosphamide 5.7216636934
MESH:D051437 Renal Insufficiency Cisplatin 3.9415464296
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 3.5818379247 11700416
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.3818990726
MESH:D012206 Rhabdomyolysis Lamivudine 5.069296927
MESH:D012512 Sarcoma, Ewing's Cisplatin 3.9814601052
MESH:D012595 Scleroderma, Systemic Cyclophosphamide 4.3816636934
MESH:D012640 Seizures 2,4-dinitrotoluene 8.0418551238
MESH:D012640 Seizures Lindane 8.0412842176 15475178 7539098
MESH:D012640 Seizures Phenobarbital 8.043137016 11442880 16876388 4039156
MESH:D003294 Seizures, Febrile Phenobarbital 4.346407741
MESH:D012871 Skin Diseases Vitamin E 2.3118709164
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 8.2419755658 10029692
MESH:D012878 Skin Neoplasms Melphalan 8.2414993021
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 8.2416192470
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 4.8615464296
MESH:D013088 Spermatocele Diethylstilbestrol 17.3216709447 16002989
MESH:D013088 Spermatocele Ethinyl Estradiol 17.3216709447
MESH:D013088 Spermatocele Tamoxifen 17.3216709447
OMIM:102530 SPERMATOGENIC FAILURE 6 Cyclophosphamide 5.0416517039
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.5619457130
MESH:D013158 Splenic Diseases Dimethylnitrosamine 4.7812587719
MESH:D013272 Stomach Diseases Dexamethasone 3.8515472012
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 5.762093021 20155912
MESH:D013274 Stomach Neoplasms Cisplatin 5.7615958060 17522103 18396642
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 5.7618456281
MESH:D013274 Stomach Neoplasms Dimethylnitrosamine 5.7616033868
MESH:D013274 Stomach Neoplasms Zidovudine 5.7617696246
MESH:D013276 Stomach Ulcer Dexamethasone 3.0815138204
MESH:D020521 Stroke Vitamin E 3.1416517955
MESH:D019966 Substance-Related Disorders bisphenol A 3.5116045194 16684133
MESH:D015173 Supratentorial Neoplasms Cyclophosphamide 11.0212837982
MESH:D015173 Supratentorial Neoplasms Thiotepa 11.0212837982
MESH:D013736 Testicular Neoplasms Cisplatin 4.1915464296 17225452
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.1811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.7515669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.4212697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 5.987505956
MESH:D013964 Thyroid Neoplasms Phenobarbital 5.981399818
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 17.1816049721
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 17.1817053015
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 17.1815464296 12973940 17225452
MESH:D001749 Urinary Bladder Neoplasms Cyclophosphamide 17.1814692829
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 17.1816712894 16452187 17306315
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 17.188653321 16712894 17572228
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 3.8410091137
MESH:D014581 Urticaria Acetaminophen 2.5410982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 8.3316803524
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 8.3316175088
MESH:D014591 Uterine Diseases bisphenol A 12.2014652134
MESH:D014591 Uterine Diseases Diethylstilbestrol 12.2014652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 13.5215809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 13.5214692618
MESH:D014594 Uterine Neoplasms Sulindac 13.5218645019
MESH:D014605 Uveitis Dexamethasone 4.331336536
MESH:D014625 Vaginal Neoplasms Cisplatin 15.8215577323
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 15.8216513791 16002989
MESH:D014625 Vaginal Neoplasms Zidovudine 15.8212579204
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.1112125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.1115869587 14671159
MESH:D014839 Vomiting Cisplatin 4.2311897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.7615886252
Pathway ID Pathway Name
KEGG:04350 TGF-beta signaling pathway
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA27177
    • No data
    Releated disease ID Related disease Name
    PA443560Breast Neoplasms
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    Releated drug ID Related drug Name
    PA450196letrozole
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB03754 - Tris(Hydroxymethyl)Aminomethane Buffers;Excipients
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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